{"ref": "bc5cdr-train-04250", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 9 mEq / l developed within 3 to 8 days of sulindac administration.", "completion": "{\"entities\": [{\"text\": \"sulindac\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-02702", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: Methamphetamine is a very addictive, powerful stimulant that increases wakefulness and physical activity and can produce other effects such as cardiac dysrhythmias, hypertension, hallucinations, and violent behavior.", "completion": "{\"entities\": [{\"text\": \"Methamphetamine\", \"type\": \"Chemical\"}, {\"text\": \"cardiac dysrhythmias\", \"type\": \"Disease\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}, {\"text\": \"hallucinations\", \"type\": \"Disease\"}, {\"text\": \"violent behavior\", \"type\": \"Disease\"}]}", "n_entities": 5} {"ref": "bc5cdr-train-04922", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Animal and clinical studies have suggested that N-methyl-D-aspartate (NMDA) antagonists, such as ketamine, may be effective in improving opioid analgesia in difficult pain syndromes, such as neuropathic pain.", "completion": "{\"entities\": [{\"text\": \"N-methyl-D-aspartate\", \"type\": \"Chemical\"}, {\"text\": \"NMDA\", \"type\": \"Chemical\"}, {\"text\": \"ketamine\", \"type\": \"Chemical\"}, {\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"neuropathic pain\", \"type\": \"Disease\"}]}", "n_entities": 5} {"ref": "bc5cdr-train-03114", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSION: In patients with risk factors, e.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-01208", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The block was successful and surgery was conducted as scheduled despite persisting atrial fibrillation.", "completion": "{\"entities\": [{\"text\": \"atrial fibrillation\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-03280", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 001 ). In the Ato + Dex group, SBP was increased from 113 +/- 2 to 119 +/- 2 mmHg on Days 4 to 14, respectively (P < 0.", "completion": "{\"entities\": [{\"text\": \"Ato\", \"type\": \"Chemical\"}, {\"text\": \"Dex\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-03501", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Comparison of the respiratory effects of i.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-02649", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We recommend caution in the use of lopinavir/ritonavir", "completion": "{\"entities\": [{\"text\": \"lopinavir/ritonavir\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-00629", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We report a case of severe citrate toxicity during volunteer donor apheresis platelet collection.", "completion": "{\"entities\": [{\"text\": \"citrate\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-01148", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Effect of some anticancer drugs and combined chemotherapy on renal toxicity.", "completion": "{\"entities\": [{\"text\": \"renal toxicity\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-02374", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A significant proportion of warfarin - related cerebral haemorrhages might have been prevented if greater caution had been taken when prescribing drugs known to interact with warfarin", "completion": "{\"entities\": [{\"text\": \"warfarin\", \"type\": \"Chemical\"}, {\"text\": \"cerebral haemorrhages\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-02941", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It is concluded that WR242511 should not be pursued as a pretreatment for CN poisoning unless the anti - CN characteristics of this compound can be successfully dissociated from those producing undesirable toxicity", "completion": "{\"entities\": [{\"text\": \"WR242511\", \"type\": \"Chemical\"}, {\"text\": \"poisoning\", \"type\": \"Disease\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-03684", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Illness occurred within 1 -- 9 weeks of commencement of therapy in 9 patients, the remaining 3 patients having received the drug for 13 months, 15 months and 7 years before experiencing symptoms.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-03710", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Clinical pharmacology and pharmacokinetics.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-04050", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Measurements included arterial ketone body ratio (AKBR, aceto-acetate / 3-hydroxybutyrate) and clinical hepatic function parameters.", "completion": "{\"entities\": [{\"text\": \"aceto-acetate\", \"type\": \"Chemical\"}, {\"text\": \"3-hydroxybutyrate\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-03197", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: There were more deaths in the mexiletine group (7.", "completion": "{\"entities\": [{\"text\": \"deaths\", \"type\": \"Disease\"}, {\"text\": \"mexiletine\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-03522", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cerebellar volume for the patient group ranged between 67.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-03312", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Individual differences in renal ACE activity in healthy rats predict susceptibility to adriamycin - induced renal damage.", "completion": "{\"entities\": [{\"text\": \"adriamycin\", \"type\": \"Chemical\"}, {\"text\": \"renal damage\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-03966", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The patient was admitted to the hospital, anticoagulated with unfractionated heparin, and given intravenous diltiazem for rate control and intravenous amiodarone for rate and rhythm control.", "completion": "{\"entities\": [{\"text\": \"heparin\", \"type\": \"Chemical\"}, {\"text\": \"diltiazem\", \"type\": \"Chemical\"}, {\"text\": \"amiodarone\", \"type\": \"Chemical\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-02484", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A series of N-pyrimidinyl-2-phenoxyacetamide adenosine A (2A) antagonists is described.", "completion": "{\"entities\": [{\"text\": \"N-pyrimidinyl-2-phenoxyacetamide\", \"type\": \"Chemical\"}, {\"text\": \"adenosine\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-00617", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The aim of this study was to assess the effects of gabapentin, a drug effective in neuropathic pain patients, on brain processing of nociceptive information in normal and central sensitization states.", "completion": "{\"entities\": [{\"text\": \"gabapentin\", \"type\": \"Chemical\"}, {\"text\": \"neuropathic pain\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-01884", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Before treatment all patients had a cardiac evaluation and during treatment serial ECG recordings were performed.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-03622", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The aorta / serum - ratio and the radioactive build - up 24 and 48 hours after injection of 131I - HSA was reduced in animals treated with D-pen for 42 days, indicating an impeded transmural transport of tracer which may be caused by a steric exclusion effect of abundant hyaluronate.", "completion": "{\"entities\": [{\"text\": \"D-pen\", \"type\": \"Chemical\"}, {\"text\": \"hyaluronate\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-00766", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: 3-methyladenine (3MA ), a specific inhibitor on autophagy was used in a heart failure model of rats induced by adriamycin.", "completion": "{\"entities\": [{\"text\": \"3-methyladenine\", \"type\": \"Chemical\"}, {\"text\": \"3MA\", \"type\": \"Chemical\"}, {\"text\": \"heart failure\", \"type\": \"Disease\"}, {\"text\": \"adriamycin\", \"type\": \"Chemical\"}]}", "n_entities": 4} {"ref": "bc5cdr-train-05129", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Ginsenoside Rg1 restores the impairment of learning induced by chronic morphine administration in rats.", "completion": "{\"entities\": [{\"text\": \"Ginsenoside Rg1\", \"type\": \"Chemical\"}, {\"text\": \"impairment of learning\", \"type\": \"Disease\"}, {\"text\": \"morphine\", \"type\": \"Chemical\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-02037", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: once daily to rats for 1, 3, 6, 9 and 12 months revealed neurological disorders indicating cerebellum damage (\" valproate encephalopathy \"). The first ultrastructural changes in structural elements of the blood - brain - barrier (BBB) in the cerebellar cortex were detectable after 3 months of the experiment.", "completion": "{\"entities\": [{\"text\": \"neurological disorders\", \"type\": \"Disease\"}, {\"text\": \"cerebellum damage\", \"type\": \"Disease\"}, {\"text\": \"valproate\", \"type\": \"Chemical\"}, {\"text\": \"encephalopathy\", \"type\": \"Disease\"}]}", "n_entities": 4} {"ref": "bc5cdr-train-01049", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The role of the renin -- angiotensin system in the maintenance of blood pressure during halothane anesthesia and sodium nitroprusside (SNP )- induced hypotension was evaluated.", "completion": "{\"entities\": [{\"text\": \"angiotensin\", \"type\": \"Chemical\"}, {\"text\": \"halothane\", \"type\": \"Chemical\"}, {\"text\": \"sodium nitroprusside\", \"type\": \"Chemical\"}, {\"text\": \"SNP\", \"type\": \"Chemical\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}]}", "n_entities": 5} {"ref": "bc5cdr-train-01392", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: All patients received CAB [leuprolide acetate (LHRH-A) 3.", "completion": "{\"entities\": [{\"text\": \"leuprolide acetate\", \"type\": \"Chemical\"}, {\"text\": \"LHRH-A\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-02157", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: They suggest that, in normal conscious rats, the central tachycardia of bromocriptine appears to predominate and to mask the bradycardia of this agonist at peripheral dopamine", "completion": "{\"entities\": [{\"text\": \"tachycardia\", \"type\": \"Disease\"}, {\"text\": \"bromocriptine\", \"type\": \"Chemical\"}, {\"text\": \"bradycardia\", \"type\": \"Disease\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}]}", "n_entities": 4} {"ref": "bc5cdr-train-04895", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Development of levodopa - induced dyskinesias in parkinsonian monkeys may depend upon rate of symptom onset and / or duration of symptoms.", "completion": "{\"entities\": [{\"text\": \"levodopa\", \"type\": \"Chemical\"}, {\"text\": \"dyskinesias\", \"type\": \"Disease\"}, {\"text\": \"parkinsonian\", \"type\": \"Disease\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-03073", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Verapamil is an effective and relatively - safe antihypertensive drug.", "completion": "{\"entities\": [{\"text\": \"Verapamil\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-04008", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the' conscious catheterized rat' model, the glomerular filtration rate (GFR) was measured as the clearance of Cr (EDTA ). The morphological analysis of the kidneys included a semi - quantitative scoring system analysing the degree of striped fibrosis, subcapsular fibrosis and the number of basophilic tubules, plus an additional stereological analysis of the total grade of fibrosis in the cortex stained with Sirius Red.", "completion": "{\"entities\": [{\"text\": \"fibrosis\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-00887", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In individuals with preexisting, high - grade coronary arterial narrowing, acute myocardial infarction may result from an increase in myocardial oxygen demand associated with cocaine - induced increase in rate - pressure product.", "completion": "{\"entities\": [{\"text\": \"acute myocardial infarction\", \"type\": \"Disease\"}, {\"text\": \"oxygen\", \"type\": \"Chemical\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-00420", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The hypotensive episodes were severe enough to require vasopressor administration.", "completion": "{\"entities\": [{\"text\": \"hypotensive\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-00284", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Accumulation of drugs was not reflected in prolonged behavioral impairment", "completion": "{\"entities\": [{\"text\": \"behavioral impairment\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-04489", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A deficient L-arginine - nitric oxide system is implicated in cortisol - induced hypertension.", "completion": "{\"entities\": [{\"text\": \"L-arginine\", \"type\": \"Chemical\"}, {\"text\": \"nitric oxide\", \"type\": \"Chemical\"}, {\"text\": \"cortisol\", \"type\": \"Chemical\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}]}", "n_entities": 4} {"ref": "bc5cdr-train-04729", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 1 mg / kg ip ), on antihyperalgesic action of selective antagonists of B2 and B1 receptors: D - Arg -[Hyp3, Thi5, D - Tic7, Oic8] bradykinin (HOE 140; 70 nmol / kg ip) or des Arg10 HOE 140 (70 nmol / kg ip) respectively, in model of diabetic (streptozotocin-induced) and toxic (vincristine-induced) neuropathy was investigated.", "completion": "{\"entities\": [{\"text\": \"bradykinin\", \"type\": \"Chemical\"}, {\"text\": \"HOE 140\", \"type\": \"Chemical\"}, {\"text\": \"des Arg10 HOE 140\", \"type\": \"Chemical\"}, {\"text\": \"diabetic (streptozotocin-induced) and toxic (vincristine-induced) neuropathy\", \"type\": \"Disease\"}]}", "n_entities": 4} {"ref": "bc5cdr-train-02323", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In Mg (2 +)- free bathing medium containing bicuculline, conditions designed to increase excitability in the slices, electrical stimulation of the hilus resulted in a single population spike in granule cells from control mice and pilocarpine - treated mice that did not experience SE.", "completion": "{\"entities\": [{\"text\": \"Mg\", \"type\": \"Chemical\"}, {\"text\": \"bicuculline\", \"type\": \"Chemical\"}, {\"text\": \"pilocarpine\", \"type\": \"Chemical\"}, {\"text\": \"SE\", \"type\": \"Disease\"}]}", "n_entities": 4} {"ref": "bc5cdr-train-03567", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The reduction of cyclosporine - or tacrolimus trough levels and the administration of calcium channel blockers led to relief of pain.", "completion": "{\"entities\": [{\"text\": \"cyclosporine\", \"type\": \"Chemical\"}, {\"text\": \"tacrolimus\", \"type\": \"Chemical\"}, {\"text\": \"calcium\", \"type\": \"Chemical\"}, {\"text\": \"pain\", \"type\": \"Disease\"}]}", "n_entities": 4} {"ref": "bc5cdr-train-03642", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 4; 95% confidence interval [CI ], 1.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-02536", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Transient cranial nerve dysfunction has been described in a few cases with topical papaverine.", "completion": "{\"entities\": [{\"text\": \"cranial nerve dysfunction\", \"type\": \"Disease\"}, {\"text\": \"papaverine\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-04651", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This randomized double - blind crossover outpatient study assessed the preference for 1 rizatriptan 10 mg tablet to 2 ergotamine 1 mg / caffeine 100 mg tablets in 439 patients treating a single migraine attack with each therapy.", "completion": "{\"entities\": [{\"text\": \"rizatriptan\", \"type\": \"Chemical\"}, {\"text\": \"ergotamine\", \"type\": \"Chemical\"}, {\"text\": \"caffeine\", \"type\": \"Chemical\"}, {\"text\": \"migraine\", \"type\": \"Disease\"}]}", "n_entities": 4} {"ref": "bc5cdr-train-01778", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Severe toxicity was correlated with the higher cumulative dose of 60 g / m2 of ifosfamide, a younger age (less than 2 1 / 2 years old ), and a predominance of vesicoprostatic tumor involvement.", "completion": "{\"entities\": [{\"text\": \"toxicity\", \"type\": \"Disease\"}, {\"text\": \"ifosfamide\", \"type\": \"Chemical\"}, {\"text\": \"tumor\", \"type\": \"Disease\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-03075", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We report a case in which myocardial infarction coincided with the introduction of captopril and the withdrawal of verapamil in a previously asymptomatic woman with severe hypertension.", "completion": "{\"entities\": [{\"text\": \"myocardial infarction\", \"type\": \"Disease\"}, {\"text\": \"captopril\", \"type\": \"Chemical\"}, {\"text\": \"verapamil\", \"type\": \"Chemical\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}]}", "n_entities": 4} {"ref": "bc5cdr-train-01385", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Significant disfiguring changes occur as a result of bone, cartilage, and soft tissue hypertrophy, including the thickening of the skin, coarsening of facial features, and cutis verticis gyrata.", "completion": "{\"entities\": [{\"text\": \"hypertrophy\", \"type\": \"Disease\"}, {\"text\": \"cutis verticis gyrata\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-00373", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: All concentrations of nicotine sulfate caused some lethality but a no effect level for coniine lethality was 0.", "completion": "{\"entities\": [{\"text\": \"nicotine\", \"type\": \"Chemical\"}, {\"text\": \"coniine\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-02537", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This study supports previous reports and provides neurophysiological evidence of an adverse effect on the auditory nerve.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-03564", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Bone scans showed an increased tracer uptake of the foot bones.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-01525", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Diazepam -, scopolamine - and ageing - induced amnesia served as the interoceptive behavioral models.", "completion": "{\"entities\": [{\"text\": \"Diazepam\", \"type\": \"Chemical\"}, {\"text\": \"scopolamine\", \"type\": \"Chemical\"}, {\"text\": \"amnesia\", \"type\": \"Disease\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-01678", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A 45 - year - old man, an admitted frequent cocaine user, presented to the Emergency Department (ED) on two separate occasions with a history of priapism after cocaine use.", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"priapism\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-04091", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: He had been prescribed telithromycin 400 mg / d PO to treat an upper respiratory tract infection 7 days prior.", "completion": "{\"entities\": [{\"text\": \"telithromycin\", \"type\": \"Chemical\"}, {\"text\": \"upper respiratory tract infection\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-02332", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: beta4 -/- mice were less sensitive to the effects of nicotine both at low doses, measured as decreased exploration in an open field, and at high doses, measured as sensitivity to nicotine - induced seizures.", "completion": "{\"entities\": [{\"text\": \"nicotine\", \"type\": \"Chemical\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-05151", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It was determined that the size of the bruising was smaller in the 30 - second injection.", "completion": "{\"entities\": [{\"text\": \"bruising\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-reassigned-04547", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, one trial analysed subgroups of 2839 relatively healthy 50 to 59 year - old women taking combined continuous HT and 1637 taking oestrogen - only HT, versus similar - sized placebo groups.", "completion": "{\"entities\": [{\"text\": \"oestrogen\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-02788", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Baseline, liver function tests were elevated in two patients (fourth patient: ALT: 122 IU / l, AST: 111 IU / l, tenth patient: ALT: 294 IU / l, AST: 274 IU / l, with minimal changes in the liver biopsy in both ). Shortly after treatment their tests normalized and during follow - up period none of the patients had abnormal liver function tests.", "completion": "{\"entities\": [{\"text\": \"abnormal liver function\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-02338", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A 14 - year - old girl is reported with recurrent, azithromycin - induced, acute interstitial nephritis.", "completion": "{\"entities\": [{\"text\": \"azithromycin\", \"type\": \"Chemical\"}, {\"text\": \"interstitial nephritis\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-04234", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A multicenter study was performed in 110 patients with superficial transitional cell carcinoma of the bladder.", "completion": "{\"entities\": [{\"text\": \"carcinoma of the bladder\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-00683", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: OBJECTIVE: To describe associations between the use of benzodiazepines or related drugs (BZDs / RDs) and health, functional abilities and cognitive function in the elderly.", "completion": "{\"entities\": [{\"text\": \"benzodiazepines\", \"type\": \"Chemical\"}, {\"text\": \"BZDs\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-04830", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Nineteen patients finished the trial, and in 18 cases the therapeutic result was considered very good to good.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-00738", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: MAIN OUTCOME MEASURE (S ): Central retinal vein occlusion after ovulation induction with CC.", "completion": "{\"entities\": [{\"text\": \"retinal vein occlusion\", \"type\": \"Disease\"}, {\"text\": \"CC\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-05226", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Dopamine turnover ratios (DOPAC: DA and HVA: DA) were found to be lower in those animals exposed to the exploratory box when compared to their home cage counterparts.", "completion": "{\"entities\": [{\"text\": \"Dopamine\", \"type\": \"Chemical\"}, {\"text\": \"DOPAC\", \"type\": \"Chemical\"}, {\"text\": \"DA\", \"type\": \"Chemical\"}, {\"text\": \"HVA\", \"type\": \"Chemical\"}]}", "n_entities": 4} {"ref": "bc5cdr-train-02473", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Patients without proteinuria had increased renal function (median 42.", "completion": "{\"entities\": [{\"text\": \"proteinuria\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-03048", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These patients had Q-T prolongation and recurrent syncope due to polymorphous ventricular tachycardia.", "completion": "{\"entities\": [{\"text\": \"Q-T prolongation\", \"type\": \"Disease\"}, {\"text\": \"syncope\", \"type\": \"Disease\"}, {\"text\": \"ventricular tachycardia\", \"type\": \"Disease\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-05190", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This receptor plays a role in regulating the structure and function of podocyte foot process.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-03171", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After a median follow - up of 22 months, the median progression free survival rate was 7 months, and the median survival time was 16 months.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-01744", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A reproducible model for producing diffuse myocardial injury (epinephrine infusion) has been developed to study the cardioprotective effects of agents or maneuvers which might alter the evolution of acute myocardial infarction.", "completion": "{\"entities\": [{\"text\": \"myocardial injury\", \"type\": \"Disease\"}, {\"text\": \"epinephrine\", \"type\": \"Chemical\"}, {\"text\": \"myocardial infarction\", \"type\": \"Disease\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-00996", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cerebral blood flow and metabolism during isoflurane - induced hypotension in patients subjected to surgery for cerebral aneurysms.", "completion": "{\"entities\": [{\"text\": \"isoflurane\", \"type\": \"Chemical\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}, {\"text\": \"cerebral aneurysms\", \"type\": \"Disease\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-04329", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Subsequent addition of phenylephrine infusion, sufficient to re - elevate mean arterial pressure to 106 +/- 4 mm Hg (P less than 0.", "completion": "{\"entities\": [{\"text\": \"phenylephrine\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-02399", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 7 %(14 of 210 patients) after iodixanol (P = 0.", "completion": "{\"entities\": [{\"text\": \"iodixanol\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-04820", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Further studies on effects of irrigation solutions on rat bladders.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-05079", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Here, we present a similar incident in a severely depressed patient who received electroconvulsive therapy (ECT ). Prolonged apnea in our case ensued because the information about suicidal attempt by OP compound", "completion": "{\"entities\": [{\"text\": \"depressed\", \"type\": \"Disease\"}, {\"text\": \"apnea\", \"type\": \"Disease\"}, {\"text\": \"OP compound\", \"type\": \"Chemical\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-01197", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Five days after the onset of the symptoms of meningitis, the patient aspirated stomach contents and needed endotracheal intubation.", "completion": "{\"entities\": [{\"text\": \"meningitis\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-02482", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Srl should be used with ACEi / ARB therapy and patients monitored for proteinuria and increased renal dysfunction", "completion": "{\"entities\": [{\"text\": \"Srl\", \"type\": \"Chemical\"}, {\"text\": \"ACEi\", \"type\": \"Chemical\"}, {\"text\": \"ARB\", \"type\": \"Chemical\"}, {\"text\": \"proteinuria\", \"type\": \"Disease\"}, {\"text\": \"renal dysfunction\", \"type\": \"Disease\"}]}", "n_entities": 5} {"ref": "bc5cdr-train-01035", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Abnormal involuntary movements appeared in the mouth, tongue, neck and abdomen of a 64 - year - old male patient after he took metoclopramide for gastrointestinal disorder in a regimen of 30 mg per day for a total of about 260 days.", "completion": "{\"entities\": [{\"text\": \"Abnormal involuntary movements\", \"type\": \"Disease\"}, {\"text\": \"metoclopramide\", \"type\": \"Chemical\"}, {\"text\": \"gastrointestinal disorder\", \"type\": \"Disease\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-04207", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Composition of gall bladder stones associated with octreotide: response to oral ursodeoxycholic acid.", "completion": "{\"entities\": [{\"text\": \"gall bladder stones\", \"type\": \"Disease\"}, {\"text\": \"octreotide\", \"type\": \"Chemical\"}, {\"text\": \"ursodeoxycholic acid\", \"type\": \"Chemical\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-reassigned-02013", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Busulfan was given p.", "completion": "{\"entities\": [{\"text\": \"Busulfan\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-00728", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: of these groups showed significant difference in percent inhibition.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-00548", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 1 - 10 microg / side) enhanced the locomotor response to cocaine; the maximum effect being observed after 10 microg / side of the agonist.", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-04028", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A case of metabolic acidosis, acute renal failure and hepatic failure following paracetamol", "completion": "{\"entities\": [{\"text\": \"metabolic acidosis\", \"type\": \"Disease\"}, {\"text\": \"acute renal failure and hepatic failure\", \"type\": \"Disease\"}, {\"text\": \"paracetamol\", \"type\": \"Chemical\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-03650", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 6 ), choanal atresia (AOR = 8.", "completion": "{\"entities\": [{\"text\": \"choanal atresia\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-04792", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Therefore NFkappaB activity, oxidative stress, neuronal nitric oxide synthase (nNOS) activity, spatial learning and memory as well as the effect of topiramate, a previously proposed therapy for cocaine addiction, were evaluated in an experimental model of cocaine administration in rats.", "completion": "{\"entities\": [{\"text\": \"nitric oxide\", \"type\": \"Chemical\"}, {\"text\": \"topiramate\", \"type\": \"Chemical\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"cocaine addiction\", \"type\": \"Disease\"}]}", "n_entities": 4} {"ref": "bc5cdr-train-02758", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The duration of apnea was compared with published data on normal subjects.", "completion": "{\"entities\": [{\"text\": \"apnea\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-03771", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pooled data from trials comparing antithrombotic treatment with placebo have shown that warfarin reduces the risk of stroke by 62 %, and that aspirin alone reduces the risk by 22 %. Overall, in high - risk patients, warfarin is superior to aspirin in preventing strokes, with a relative risk reduction of 36 %. Ximelagatran, an oral direct thrombin inhibitor, was found to be as efficient as vitamin K antagonist drugs in the prevention of embolic events, but has been recently withdrawn because of abnormal liver function tests.", "completion": "{\"entities\": [{\"text\": \"warfarin\", \"type\": \"Chemical\"}, {\"text\": \"stroke\", \"type\": \"Disease\"}, {\"text\": \"aspirin\", \"type\": \"Chemical\"}, {\"text\": \"strokes\", \"type\": \"Disease\"}, {\"text\": \"Ximelagatran\", \"type\": \"Chemical\"}, {\"text\": \"vitamin K\", \"type\": \"Chemical\"}, {\"text\": \"embolic events\", \"type\": \"Disease\"}, {\"text\": \"abnormal liver function\", \"type\": \"Disease\"}]}", "n_entities": 8} {"ref": "bc5cdr-train-04271", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: On two paradoxical side - effects of prednisolone in rats, ribosomal RNA biosyntheses, and a mechanism of action.", "completion": "{\"entities\": [{\"text\": \"prednisolone\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-01048", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Rebound hypertensive after sodium nitroprusside prevented by saralasin in rats.", "completion": "{\"entities\": [{\"text\": \"hypertensive\", \"type\": \"Disease\"}, {\"text\": \"sodium nitroprusside\", \"type\": \"Chemical\"}, {\"text\": \"saralasin\", \"type\": \"Chemical\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-00205", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Compression neuropathy of the radial nerve due to pentazocine - induced fibrous myopathy.", "completion": "{\"entities\": [{\"text\": \"Compression neuropathy of the radial nerve\", \"type\": \"Disease\"}, {\"text\": \"pentazocine\", \"type\": \"Chemical\"}, {\"text\": \"fibrous myopathy\", \"type\": \"Disease\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-00920", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The dosing schedule, duration of lithium treatment, and daily dose of lithium did not affect maximum osmolality or creatinine clearance.", "completion": "{\"entities\": [{\"text\": \"lithium\", \"type\": \"Chemical\"}, {\"text\": \"creatinine\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-02582", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In each patient, the close temporal association between the commencement of sirolimus therapy and proteinuria implicated sirolimus as the most likely etiology of the proteinuria.", "completion": "{\"entities\": [{\"text\": \"sirolimus\", \"type\": \"Chemical\"}, {\"text\": \"proteinuria\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-01312", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Histological and immunohistochemical investigations (HE - LFB, CD - 68, Neurofilament) revealed degeneration of myelin and axons as well as pseudocystic transformation in areas exposed to vincristine, accompanied by secondary changes with numerous prominent macrophages.", "completion": "{\"entities\": [{\"text\": \"degeneration of myelin and axons\", \"type\": \"Disease\"}, {\"text\": \"pseudocystic transformation\", \"type\": \"Disease\"}, {\"text\": \"vincristine\", \"type\": \"Chemical\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-02242", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The combination inhibited intestinal transit similar to that produced by morphine regardless of the time of treatment, suggesting that metamizol did not potentiate morphine - induced constipation.", "completion": "{\"entities\": [{\"text\": \"morphine\", \"type\": \"Chemical\"}, {\"text\": \"metamizol\", \"type\": \"Chemical\"}, {\"text\": \"constipation\", \"type\": \"Disease\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-03487", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In salt - depleted rats, amphotericin B decreased creatinine clearance linearly with time, with an 85% reduction by week 3.", "completion": "{\"entities\": [{\"text\": \"amphotericin B\", \"type\": \"Chemical\"}, {\"text\": \"creatinine\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-04715", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: We sent a questionnaire concerning complications of indocyanine green to 32 institutions in Japan, which were selected on the basis of the client list from the Topcon Company, which manufactures the indocyanine green fundus camera.", "completion": "{\"entities\": [{\"text\": \"indocyanine green\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-01781", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Previous studies have suggested that repeated exposure of rats to the drug or to the experimental environment is necessary to observe nicotine - induced locomotor stimulation.", "completion": "{\"entities\": [{\"text\": \"nicotine\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-00466", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The first series of experiments examined the influence of age and growth status on artery calcification in Warfarin - treated rats.", "completion": "{\"entities\": [{\"text\": \"artery calcification\", \"type\": \"Disease\"}, {\"text\": \"Warfarin\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-00473", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The second set of experiments examined the possible synergy between vitamin D and Warfarin in artery calcification.", "completion": "{\"entities\": [{\"text\": \"vitamin D\", \"type\": \"Chemical\"}, {\"text\": \"Warfarin\", \"type\": \"Chemical\"}, {\"text\": \"artery calcification\", \"type\": \"Disease\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-03366", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The t (1 / 2, z) of desipramine was longer when desipramine was coadministered with cinacalcet (21.", "completion": "{\"entities\": [{\"text\": \"desipramine\", \"type\": \"Chemical\"}, {\"text\": \"cinacalcet\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-00321", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The addition of 1 mM adenosine to the myocardial cell cultures markedly increases the ATP concentration through a pathway reportedly leading to a compartmentalized ATP pool.", "completion": "{\"entities\": [{\"text\": \"adenosine\", \"type\": \"Chemical\"}, {\"text\": \"ATP\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-04708", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: All patients recovered without sequelae.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-03051", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the seventh patient, a permanent ventricular pacemaker was inserted and, despite continuation of procainamide therapy, polymorphous ventricular tachycardia did not reoccur.", "completion": "{\"entities\": [{\"text\": \"procainamide\", \"type\": \"Chemical\"}, {\"text\": \"ventricular tachycardia\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-04869", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 7 %). Patients' mean age was 53.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-03453", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Design and analysis of the HYPREN - trial: safety of enalapril and prazosin in the initial treatment phase of patients with congestive heart failure.", "completion": "{\"entities\": [{\"text\": \"enalapril\", \"type\": \"Chemical\"}, {\"text\": \"prazosin\", \"type\": \"Chemical\"}, {\"text\": \"congestive heart failure\", \"type\": \"Disease\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-03997", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: All of these positive GABA (A) modulators suppressed the expression of kindled seizures, whereas only allopregnanolone and ganaxolone inhibited the development of kindling.", "completion": "{\"entities\": [{\"text\": \"GABA\", \"type\": \"Chemical\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}, {\"text\": \"allopregnanolone\", \"type\": \"Chemical\"}, {\"text\": \"ganaxolone\", \"type\": \"Chemical\"}]}", "n_entities": 4} {"ref": "bc5cdr-train-02859", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Liver disease caused by propylthiouracil.", "completion": "{\"entities\": [{\"text\": \"Liver disease\", \"type\": \"Disease\"}, {\"text\": \"propylthiouracil\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-00993", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Following major intracranial surgery in a 35 - year - old man, sodium pentothal was intravenously infused to minimize cerebral ischaemia.", "completion": "{\"entities\": [{\"text\": \"sodium pentothal\", \"type\": \"Chemical\"}, {\"text\": \"cerebral ischaemia\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-02398", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 4 %(9 of 204 patients) after iopamidol and 6.", "completion": "{\"entities\": [{\"text\": \"iopamidol\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-04691", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Haematological toxicity was greater for the combination than AraG alone, although median time to neutrophil and platelet recovery was consistent with other salvage therapies.", "completion": "{\"entities\": [{\"text\": \"Haematological toxicity\", \"type\": \"Disease\"}, {\"text\": \"AraG\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-00376", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: There was a statistically significant (P < or = 0.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-04693", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Our experience supports the safety of giving AraG as salvage therapy in synchrony with etoposide and cyclophosphamide, although neurological toxicity", "completion": "{\"entities\": [{\"text\": \"AraG\", \"type\": \"Chemical\"}, {\"text\": \"etoposide\", \"type\": \"Chemical\"}, {\"text\": \"cyclophosphamide\", \"type\": \"Chemical\"}, {\"text\": \"neurological toxicity\", \"type\": \"Disease\"}]}", "n_entities": 4} {"ref": "bc5cdr-train-02238", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 2 mg / kg naloxone s.", "completion": "{\"entities\": [{\"text\": \"naloxone\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-01240", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Data from a Transnational case - control study were used to assess the risk of VTE for the latter patterns of use, while accounting for duration of use.", "completion": "{\"entities\": [{\"text\": \"VTE\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-03359", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: OBJECTIVE: In vitro work has demonstrated that cinacalcet is a strong inhibitor of cytochrome P450 isoenzyme (CYP) 2D6.", "completion": "{\"entities\": [{\"text\": \"cinacalcet\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-00609", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These data suggest that U-II may be involved in some aspects of psychiatric disorders", "completion": "{\"entities\": [{\"text\": \"U-II\", \"type\": \"Chemical\"}, {\"text\": \"psychiatric disorders\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-00971", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: There was no serologic evidence of viral infection, and a liver biopsy sample showed a histologic pattern consistent with drug-induced hepatitis.", "completion": "{\"entities\": [{\"text\": \"viral infection\", \"type\": \"Disease\"}, {\"text\": \"drug-induced hepatitis\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-04572", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Amantadine treatment produced a biphasic effect on mouse motility.", "completion": "{\"entities\": [{\"text\": \"Amantadine\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-01167", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSION: In this preliminary report, divalproex sodium was a superior alternative to lithium in bipolar patients experiencing cognitive deficits, loss of creativity, and functional impairments", "completion": "{\"entities\": [{\"text\": \"divalproex sodium\", \"type\": \"Chemical\"}, {\"text\": \"lithium\", \"type\": \"Chemical\"}, {\"text\": \"bipolar\", \"type\": \"Disease\"}, {\"text\": \"cognitive deficits\", \"type\": \"Disease\"}, {\"text\": \"loss of creativity\", \"type\": \"Disease\"}, {\"text\": \"functional impairments\", \"type\": \"Disease\"}]}", "n_entities": 6} {"ref": "bc5cdr-train-reassigned-02917", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After the addition of clonidine 0.", "completion": "{\"entities\": [{\"text\": \"clonidine\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-02890", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Trimipramine (TRI ), which shows a clinical antidepressant activity, is chemically related to imipramine but does not inhibit the reuptake of noradrenaline and 5-hydroxytryptamine, nor does it induce beta - adrenergic down - regulation.", "completion": "{\"entities\": [{\"text\": \"Trimipramine\", \"type\": \"Chemical\"}, {\"text\": \"imipramine\", \"type\": \"Chemical\"}, {\"text\": \"TRI\", \"type\": \"Chemical\"}, {\"text\": \"antidepressant\", \"type\": \"Chemical\"}, {\"text\": \"noradrenaline\", \"type\": \"Chemical\"}, {\"text\": \"5-hydroxytryptamine\", \"type\": \"Chemical\"}]}", "n_entities": 6} {"ref": "bc5cdr-train-03831", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Myopathy, associated in some cases with myoglobinuria, and in 2 cases with transient renal failure, has been rarely reported with lovastatin, especially in patients concomitantly treated with cyclosporin, gemfibrozil or niacin.", "completion": "{\"entities\": [{\"text\": \"Myopathy\", \"type\": \"Disease\"}, {\"text\": \"myoglobinuria\", \"type\": \"Disease\"}, {\"text\": \"renal failure\", \"type\": \"Disease\"}, {\"text\": \"lovastatin\", \"type\": \"Chemical\"}, {\"text\": \"cyclosporin\", \"type\": \"Chemical\"}, {\"text\": \"gemfibrozil\", \"type\": \"Chemical\"}, {\"text\": \"niacin\", \"type\": \"Chemical\"}]}", "n_entities": 7} {"ref": "bc5cdr-train-01029", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Veno-occlusive liver disease after dacarbazine therapy (DTIC) for melanoma.", "completion": "{\"entities\": [{\"text\": \"Veno-occlusive liver disease\", \"type\": \"Disease\"}, {\"text\": \"dacarbazine\", \"type\": \"Chemical\"}, {\"text\": \"DTIC\", \"type\": \"Chemical\"}, {\"text\": \"melanoma\", \"type\": \"Disease\"}]}", "n_entities": 4} {"ref": "bc5cdr-train-01253", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The development of apomorphine - induced (1.", "completion": "{\"entities\": [{\"text\": \"apomorphine\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-00870", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These data indicate that nitroprusside infusion rates that decrease mean arterial blood pressure by 40 - 50 per cent do not change cardiac output or QS / QT.", "completion": "{\"entities\": [{\"text\": \"nitroprusside\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-03360", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The purpose of this study was to evaluate the effect of cinacalcet on CYP2D6 activity, using desipramine as a probe substrate, in healthy subjects.", "completion": "{\"entities\": [{\"text\": \"cinacalcet\", \"type\": \"Chemical\"}, {\"text\": \"desipramine\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-04644", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The corresponding urine concentrations amounted to 374 and 554 mg / l.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-03946", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Analysis of neurotransmitter concentration in some brain regions on the test day showed that dopamine concentration of the vehicle / scopolamine group was significantly lower than that of the vehicle / vehicle group, but this phenomenon was reversed when s-limonene or s-perillyl alcohol were administered before the injection of scopolamine", "completion": "{\"entities\": [{\"text\": \"dopamine\", \"type\": \"Chemical\"}, {\"text\": \"scopolamine\", \"type\": \"Chemical\"}, {\"text\": \"s-limonene\", \"type\": \"Chemical\"}, {\"text\": \"s-perillyl alcohol\", \"type\": \"Chemical\"}]}", "n_entities": 4} {"ref": "bc5cdr-train-05144", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHOD: The sample for the study consisted of 50 patients to whom subcutaneous heparin was administered.", "completion": "{\"entities\": [{\"text\": \"heparin\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-03012", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We report a case of bile duct hamartoma which developed in a patient who had been on long - term danazol treatment.", "completion": "{\"entities\": [{\"text\": \"bile duct hamartoma\", \"type\": \"Disease\"}, {\"text\": \"danazol\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-03491", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, at the end of 3 weeks, amphotericin B levels in the kidneys and liver were significantly higher in salt - depleted and normal - salt rats than those in salt - loaded rats, with plasma / kidney ratios of 21, 14, and 8 in salt - depleted, normal - salt, and salt - loaded rats, respectively.", "completion": "{\"entities\": [{\"text\": \"amphotericin B\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-03463", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It was concluded that treatment with enalapril was well tolerated and it is, therefore, unreasonable to restrict the initiation of treatment with enalapril", "completion": "{\"entities\": [{\"text\": \"enalapril\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-00157", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Depressed mood was more common among patients and was associated with certain sexual difficulties, but not with impotence.", "completion": "{\"entities\": [{\"text\": \"Depressed mood\", \"type\": \"Disease\"}, {\"text\": \"impotence\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-01546", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After the injection, there was a reduction in radicular symptoms.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-04558", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In our experience and according to the literature, FK506 does not seem to cross - react with cyclosporin A (CyA ), an immuno - suppressive drug already known to induce MAHA", "completion": "{\"entities\": [{\"text\": \"FK506\", \"type\": \"Chemical\"}, {\"text\": \"cyclosporin A\", \"type\": \"Chemical\"}, {\"text\": \"CyA\", \"type\": \"Chemical\"}, {\"text\": \"MAHA\", \"type\": \"Disease\"}]}", "n_entities": 4} {"ref": "bc5cdr-train-00332", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Other possible causes of rapidly progressive glomerulonephritis were investigated and ruled out.", "completion": "{\"entities\": [{\"text\": \"glomerulonephritis\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-00081", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Patients who are unusually sensitive to the neuromuscular effects of magnesium should be suspected of having an underlying disorder of neuromuscular transmission", "completion": "{\"entities\": [{\"text\": \"magnesium\", \"type\": \"Chemical\"}, {\"text\": \"disorder of neuromuscular transmission\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-00635", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Empirical treatment with intravenous calcium gluconate was initiated, and muscle contractions slowly subsided over approximately 10 to 15 minutes.", "completion": "{\"entities\": [{\"text\": \"calcium gluconate\", \"type\": \"Chemical\"}, {\"text\": \"muscle contractions\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-04471", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Catecholamine - induced cardiomyopathy due to chronic excess of endogenous catecholamines has been recognized for decades as a clinical phenomenon.", "completion": "{\"entities\": [{\"text\": \"Catecholamine\", \"type\": \"Chemical\"}, {\"text\": \"cardiomyopathy\", \"type\": \"Disease\"}, {\"text\": \"catecholamines\", \"type\": \"Chemical\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-01314", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A review of all reported cases in the literature is given.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-03090", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This is the first report of such an unusual reaction to carbamazepine", "completion": "{\"entities\": [{\"text\": \"carbamazepine\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-04615", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The possible additive role of pharmacologic agents in precipitating cardiac disturbances in patients with respiratory failure has only recently been emphasized.", "completion": "{\"entities\": [{\"text\": \"cardiac disturbances\", \"type\": \"Disease\"}, {\"text\": \"respiratory failure\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-00179", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Two days before admission diltiazem (60 mg b.", "completion": "{\"entities\": [{\"text\": \"diltiazem\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-01127", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thus, acetaminophen has been used both as a single agent and in combination with other analgesics, whereas phenacetin was available only in combinations.", "completion": "{\"entities\": [{\"text\": \"acetaminophen\", \"type\": \"Chemical\"}, {\"text\": \"phenacetin\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-02959", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A new method using a commercially available, pen - shaped laser pointer was developed.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-00025", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It is longer acting than physostigmine and is used in anaesthesia to reverse the non - depolarizing neuromuscular block.", "completion": "{\"entities\": [{\"text\": \"physostigmine\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-02704", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Oral rehabilitation of patients using methamphetamine can be challenging.", "completion": "{\"entities\": [{\"text\": \"methamphetamine\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-04946", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: in 107 patients but normal in 40% at repeat determination.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-02655", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It was shown that memory dissociation occurred in both groups.", "completion": "{\"entities\": [{\"text\": \"memory dissociation\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-01786", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 mg / kg) caused a significant increase in locomotor activity in rats that were habituated to the test environment, but had only a weak and delayed stimulant action in rats that were unfamiliar with the test environment.", "completion": "{\"entities\": [{\"text\": \"increase in locomotor activity\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-00883", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It is concluded that L-dopa enhances reflex bradycardia through central alpha - receptor stimulation.", "completion": "{\"entities\": [{\"text\": \"L-dopa\", \"type\": \"Chemical\"}, {\"text\": \"bradycardia\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-04377", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Epidemiological evidence indicates that prenatal nutritional deprivation may increase the risk of schizophrenia.", "completion": "{\"entities\": [{\"text\": \"schizophrenia\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-reassigned-04079", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5% with epinephrine 2.", "completion": "{\"entities\": [{\"text\": \"epinephrine\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-02854", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These results indicate a reliable memory for magnitude and duration of experimentally induced pain", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-03014", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: If the patient develops a liver mass", "completion": "{\"entities\": [{\"text\": \"liver mass\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-02003", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Dup 753 prevents the development of puromycin aminonucleoside - induced nephrosis.", "completion": "{\"entities\": [{\"text\": \"Dup 753\", \"type\": \"Chemical\"}, {\"text\": \"puromycin aminonucleoside\", \"type\": \"Chemical\"}, {\"text\": \"nephrosis\", \"type\": \"Disease\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-02051", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: We present a case of presumed amikacin retinal toxicity following treatment with amikacin and vancomycin for alpha - haemolytic streptococcal endophthalmitis.", "completion": "{\"entities\": [{\"text\": \"amikacin\", \"type\": \"Chemical\"}, {\"text\": \"retinal toxicity\", \"type\": \"Disease\"}, {\"text\": \"vancomycin\", \"type\": \"Chemical\"}, {\"text\": \"streptococcal endophthalmitis\", \"type\": \"Disease\"}]}", "n_entities": 4} {"ref": "bc5cdr-train-03257", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 8% sevoflurane to investigate the mechanism of the anticonvulsive effects.", "completion": "{\"entities\": [{\"text\": \"sevoflurane\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-00646", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Proteinuria increased from 0.", "completion": "{\"entities\": [{\"text\": \"Proteinuria\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-04047", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Combined effects of prolonged prostaglandin E1 (PGE1 )- induced hypotension and haemodilution on hepatic function were studied in 30 patients undergoing hip surgery.", "completion": "{\"entities\": [{\"text\": \"prostaglandin E1\", \"type\": \"Chemical\"}, {\"text\": \"PGE1\", \"type\": \"Chemical\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}, {\"text\": \"haemodilution\", \"type\": \"Disease\"}]}", "n_entities": 4} {"ref": "bc5cdr-train-02057", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In a patient with WPW syndrome and idiopathic dilated cardiomyopathy, intractable atrioventricular reentrant tachycardia (AVRT) was iatrogenically induced.", "completion": "{\"entities\": [{\"text\": \"WPW syndrome\", \"type\": \"Disease\"}, {\"text\": \"idiopathic dilated cardiomyopathy\", \"type\": \"Disease\"}, {\"text\": \"atrioventricular reentrant tachycardia\", \"type\": \"Disease\"}, {\"text\": \"AVRT\", \"type\": \"Disease\"}]}", "n_entities": 4} {"ref": "bc5cdr-train-04557", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: FK506 - associated MAHA is probably rare but physicians must be aware of this severe complication.", "completion": "{\"entities\": [{\"text\": \"FK506\", \"type\": \"Chemical\"}, {\"text\": \"MAHA\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-04257", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Preoperative assessment should focus on cardiovascular status and serum potassium level.", "completion": "{\"entities\": [{\"text\": \"potassium\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-01669", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Of 24 evaluable patients, two achieved a complete remission and one achieved a partial remission for an overall response rate of 12.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-04952", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These data are lower than those we found during the last 2 decades (overall prolactin greater than 20 ng ./ ml.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-02950", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Postmortem cytoarchitectural features identifying A1 were correlated with the electrophysiologic data.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-01024", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the singleton pregnancy, the mother had ulcerative colitis, and the infant, a male, had coarctation of the aorta and a ventricular septal defect.", "completion": "{\"entities\": [{\"text\": \"ulcerative colitis\", \"type\": \"Disease\"}, {\"text\": \"coarctation of the aorta\", \"type\": \"Disease\"}, {\"text\": \"ventricular septal defect\", \"type\": \"Disease\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-01063", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: One of the latter two patients further experienced a cytolytic hepatitis which appeared after Benzylthiouracil (Basd ne) had replaced carbimazole.", "completion": "{\"entities\": [{\"text\": \"hepatitis\", \"type\": \"Disease\"}, {\"text\": \"Benzylthiouracil\", \"type\": \"Chemical\"}, {\"text\": \"Basd ne\", \"type\": \"Chemical\"}, {\"text\": \"carbimazole\", \"type\": \"Chemical\"}]}", "n_entities": 4} {"ref": "bc5cdr-train-03203", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Calcitonin receptors are found in the brain, and intracerebral infusions of calcitonin can produce behavioral effects.", "completion": "{\"entities\": [{\"text\": \"Calcitonin\", \"type\": \"Chemical\"}, {\"text\": \"calcitonin\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-05112", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Lamivudine for the prevention of hepatitis B virus reactivation in hepatitis-B surface antigen (HBSAG) seropositive cancer patients undergoing cytotoxic chemotherapy.", "completion": "{\"entities\": [{\"text\": \"Lamivudine\", \"type\": \"Chemical\"}, {\"text\": \"hepatitis B\", \"type\": \"Disease\"}, {\"text\": \"hepatitis-B surface antigen\", \"type\": \"Chemical\"}, {\"text\": \"HBSAG\", \"type\": \"Chemical\"}, {\"text\": \"cancer\", \"type\": \"Disease\"}]}", "n_entities": 5} {"ref": "bc5cdr-train-00753", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Male Wistar rats were challenged intragastrically once daily for 9 days with 1.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-reassigned-04142", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The cognitive functions remained unchanged.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-01221", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the same experimental conditions, PG-9 (5 - 20 microg per mouse, i.", "completion": "{\"entities\": [{\"text\": \"PG-9\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-01964", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The ratio of cimetidine clearance to creatinine clearance (Rc) averaged 4.", "completion": "{\"entities\": [{\"text\": \"cimetidine\", \"type\": \"Chemical\"}, {\"text\": \"creatinine\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-02535", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: Papaverine hydrochloride is a direct - acting vasodilator used to manage vasospasm during various neurosurgical operations.", "completion": "{\"entities\": [{\"text\": \"Papaverine hydrochloride\", \"type\": \"Chemical\"}, {\"text\": \"vasospasm\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-02348", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The nitric oxide (NO) inhibitor nitro-L-arginine methyl ester (L-NAME) may act as an otoprotectant against high-frequency hearing loss caused by gentamicin, but further studies are needed to confirm this.", "completion": "{\"entities\": [{\"text\": \"nitric oxide\", \"type\": \"Chemical\"}, {\"text\": \"NO\", \"type\": \"Chemical\"}, {\"text\": \"nitro-L-arginine methyl ester\", \"type\": \"Chemical\"}, {\"text\": \"L-NAME\", \"type\": \"Chemical\"}, {\"text\": \"high-frequency hearing loss\", \"type\": \"Disease\"}, {\"text\": \"gentamicin\", \"type\": \"Chemical\"}]}", "n_entities": 6} {"ref": "bc5cdr-train-02986", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: PATIENTS: Seventy men, aged 50 - 80 years, with advanced androgen - independent prostate cancer.", "completion": "{\"entities\": [{\"text\": \"prostate cancer\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-04362", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Furthermore, it was found that the magnitude of attentional modulation in secondary hyperalgesia is very similar to that of capsaicin - untreated, control condition.", "completion": "{\"entities\": [{\"text\": \"hyperalgesia\", \"type\": \"Disease\"}, {\"text\": \"capsaicin\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-02088", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This method allowed frequent self - dosing of pethidine at short time intervals and rapid accumulation of pethidine and norpethidine.", "completion": "{\"entities\": [{\"text\": \"pethidine\", \"type\": \"Chemical\"}, {\"text\": \"norpethidine\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-05162", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: c .) for 4 weeks caused an increase in vacuous chewing, tongue protrusion and duration of facial twitching observed in four weekly evaluations.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-04709", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We report a case of a 31 year old female who required admission to the Intensive Care Unit for ventilation and full supportive therapy, following ingestion of 13.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-01960", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Age and renal clearance of cimetidine.", "completion": "{\"entities\": [{\"text\": \"cimetidine\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-03209", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We present a case of paramedic misjudgment in the execution of a protocol for the treatment of allergic reaction in a case of pulmonary edema with wheezing.", "completion": "{\"entities\": [{\"text\": \"allergic reaction\", \"type\": \"Disease\"}, {\"text\": \"pulmonary edema\", \"type\": \"Disease\"}, {\"text\": \"wheezing\", \"type\": \"Disease\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-01161", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Lithium - associated cognitive and functional deficits reduced by a switch to divalproex sodium: a case series.", "completion": "{\"entities\": [{\"text\": \"Lithium\", \"type\": \"Chemical\"}, {\"text\": \"cognitive and functional deficits\", \"type\": \"Disease\"}, {\"text\": \"divalproex sodium\", \"type\": \"Chemical\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-03755", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It was administered by 15 min infusion to 16 evaluable patients with non-small cell lung cancer (NSCLC )(7 with no prior treatment, 9 patients in relapse following surgery / radiotherapy) at a dose (648 mg / m2 divided over 3 days, repeated every 3 weeks) determined by phase I trial.", "completion": "{\"entities\": [{\"text\": \"non-small cell lung cancer\", \"type\": \"Disease\"}, {\"text\": \"NSCLC\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-04542", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: From observations of the vasculature, altered distribution patterns of vessels were identified in the exencephalic head.", "completion": "{\"entities\": [{\"text\": \"exencephalic\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-01058", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: OBJECTIVE: This study was conducted to assess the occurrence of hepatic adverse effects encountered with antithyroid drugs.", "completion": "{\"entities\": [{\"text\": \"hepatic adverse effects\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-04677", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The most common adverse events (incidence > or = 5% in one group) after rizatriptan and ergotamine / caffeine, respectively, were dizziness (6.", "completion": "{\"entities\": [{\"text\": \"rizatriptan\", \"type\": \"Chemical\"}, {\"text\": \"ergotamine\", \"type\": \"Chemical\"}, {\"text\": \"caffeine\", \"type\": \"Chemical\"}, {\"text\": \"dizziness\", \"type\": \"Disease\"}]}", "n_entities": 4} {"ref": "bc5cdr-train-01125", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This apparent difference in risk may not be due to differences in nephrotoxic potential of the drugs themselves.", "completion": "{\"entities\": [{\"text\": \"nephrotoxic\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-00415", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Through 30 years of widespread use, acetaminophen has been shown to be a remarkably safe medication in therapeutic dosages.", "completion": "{\"entities\": [{\"text\": \"acetaminophen\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-02547", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The average recovery time of BAEP waveforms to pre - papaverine baseline values was 39 min.", "completion": "{\"entities\": [{\"text\": \"papaverine\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-01456", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The results show that pretreatment with TCR may be useful in preventing the damage induced by isoproterenol", "completion": "{\"entities\": [{\"text\": \"TCR\", \"type\": \"Chemical\"}, {\"text\": \"isoproterenol\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-03581", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The most common manifestation, observed in 15 further cases, was isolated optic atrophy.", "completion": "{\"entities\": [{\"text\": \"optic atrophy\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-03475", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 675 mM (LNa + LCa) and 31 +/- 5% by lowering [Na] o to 78 mM plus increasing [Ca] o to 3.", "completion": "{\"entities\": [{\"text\": \"Na\", \"type\": \"Chemical\"}, {\"text\": \"Ca\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-00924", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thermal enhancement of Adriamycin - mediated antitumor activity and normal tissue toxicities by whole body hyperthermia were compared using a F344 rat model.", "completion": "{\"entities\": [{\"text\": \"Adriamycin\", \"type\": \"Chemical\"}, {\"text\": \"toxicities\", \"type\": \"Disease\"}, {\"text\": \"hyperthermia\", \"type\": \"Disease\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-02208", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Histopathological examination of kidney, heart and lung sections revealed moderate to massive tissue damage with a variety of morphological aberrations by all the three drugs in the absence of GSPE preexposure than in its presence.", "completion": "{\"entities\": [{\"text\": \"tissue damage\", \"type\": \"Disease\"}, {\"text\": \"GSPE\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-03056", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Permeability of the blood - brain barrier was quantitated by clearance of fluorescent - labeled dextran before and during phenylephrine - induced acute hypertension in rats treated with vehicle and Hoe-140 (0.", "completion": "{\"entities\": [{\"text\": \"dextran\", \"type\": \"Chemical\"}, {\"text\": \"phenylephrine\", \"type\": \"Chemical\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}, {\"text\": \"Hoe-140\", \"type\": \"Chemical\"}]}", "n_entities": 4} {"ref": "bc5cdr-train-02791", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In three additional patients, HBV DNA levels were increased during follow - up.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-02542", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: FINDINGS: A temporal relationship was found between topical papaverine and BAEP changes leading to complete waveform loss.", "completion": "{\"entities\": [{\"text\": \"papaverine\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-02160", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Previous investigations have determined that, in response to clonidine, ultrasound production increases through the 2nd - week postpartum and decreases thereafter.", "completion": "{\"entities\": [{\"text\": \"clonidine\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-04020", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Rats were treated with seven day intravenous infusion of fucoidan (30 micrograms h - 1) or vehicle.", "completion": "{\"entities\": [{\"text\": \"fucoidan\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-02654", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In Group 2 the rats were trained to approach different shelves in different drug states.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-00787", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In addition, working memory processing in ecstasy users has been shown to be associated with neural alterations in hippocampal and / or cortical regions as measured by functional magnetic resonance imaging (fMRI ). Using functional imaging and a face - learning task, we investigated neural correlates of encoding and recalling face - name associations in 20 recreational drug users whose predominant drug use was ecstasy and 20 controls.", "completion": "{\"entities\": [{\"text\": \"ecstasy\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-03493", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Reversible inferior colliculus lesion in metronidazole - induced encephalopathy: magnetic resonance findings on diffusion - weighted and fluid attenuated inversion recovery imaging.", "completion": "{\"entities\": [{\"text\": \"inferior colliculus lesion\", \"type\": \"Disease\"}, {\"text\": \"metronidazole\", \"type\": \"Chemical\"}, {\"text\": \"encephalopathy\", \"type\": \"Disease\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-00009", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The patient had no apparent associated conditions which might have predisposed him to the development of bradyarrhythmias; and, thus, this probably represented a true idiosyncrasy to lidocaine", "completion": "{\"entities\": [{\"text\": \"bradyarrhythmias\", \"type\": \"Disease\"}, {\"text\": \"lidocaine\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-04366", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In Dahl salt - sensitive rats (DS ), high - salt (HS) diet increases BP more in males than females.", "completion": "{\"entities\": [{\"text\": \"salt\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-03234", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The effects of sevoflurane on lidocaine - induced convulsions.", "completion": "{\"entities\": [{\"text\": \"sevoflurane\", \"type\": \"Chemical\"}, {\"text\": \"lidocaine\", \"type\": \"Chemical\"}, {\"text\": \"convulsions\", \"type\": \"Disease\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-04233", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Early adjuvant adriamycin in superficial bladder carcinoma.", "completion": "{\"entities\": [{\"text\": \"adriamycin\", \"type\": \"Chemical\"}, {\"text\": \"bladder carcinoma\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-03041", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The underlying epileptogenecity of the patients or the synergistic effects of the accompanying drugs is required to trigger the de novo absence seizure.", "completion": "{\"entities\": [{\"text\": \"absence seizure\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-02222", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Metamizol potentiates morphine antinociception but not constipation after chronic treatment.", "completion": "{\"entities\": [{\"text\": \"Metamizol\", \"type\": \"Chemical\"}, {\"text\": \"morphine\", \"type\": \"Chemical\"}, {\"text\": \"constipation\", \"type\": \"Disease\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-05153", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: It was determined that injection duration had an effect on bruising and pain following the subcutaneous administration of heparin.", "completion": "{\"entities\": [{\"text\": \"bruising\", \"type\": \"Disease\"}, {\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"heparin\", \"type\": \"Chemical\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-04795", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In contrast, learning of new tasks was enhanced and correlated with the increase of nNOS activity and the decrease of glutathione peroxidase.", "completion": "{\"entities\": [{\"text\": \"glutathione\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-00310", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The data extend the findings of other investigators, further establishing the DES - induced tumor", "completion": "{\"entities\": [{\"text\": \"DES\", \"type\": \"Chemical\"}, {\"text\": \"tumor\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-01946", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Because of the rapid systemic clearance of BCNU (1,3-bis-(2-chloroethyl)-1-nitrosourea ), intra - arterial administration should provide a substantial advantage over intravenous administration for the treatment of malignant gliomas.", "completion": "{\"entities\": [{\"text\": \"BCNU\", \"type\": \"Chemical\"}, {\"text\": \"1,3-bis-(2-chloroethyl)-1-nitrosourea\", \"type\": \"Chemical\"}, {\"text\": \"malignant gliomas\", \"type\": \"Disease\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-03396", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We report 19 patients with VPA - associated encephalopathy", "completion": "{\"entities\": [{\"text\": \"VPA\", \"type\": \"Chemical\"}, {\"text\": \"encephalopathy\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-01774", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Renal function was investigated by measuring plasma and urinary electrolytes, glucosuria, proteinuria, aminoaciduria, urinary pH, osmolarity, creatinine clearance, phosphate tubular reabsorption, beta 2 microglobulinuria, and lysozymuria.", "completion": "{\"entities\": [{\"text\": \"glucosuria\", \"type\": \"Disease\"}, {\"text\": \"proteinuria\", \"type\": \"Disease\"}, {\"text\": \"aminoaciduria\", \"type\": \"Disease\"}, {\"text\": \"creatinine\", \"type\": \"Chemical\"}, {\"text\": \"phosphate\", \"type\": \"Chemical\"}]}", "n_entities": 5} {"ref": "bc5cdr-train-01272", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The possible interaction of tizanidine and other antihypertensive agents should be kept in mind when prescribing therapy to treat either hypertension or spasticity", "completion": "{\"entities\": [{\"text\": \"tizanidine\", \"type\": \"Chemical\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}, {\"text\": \"spasticity\", \"type\": \"Disease\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-02166", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Differential effects of systemically administered ketamine and lidocaine on dynamic and static hyperalgesia induced by intradermal capsaicin in humans.", "completion": "{\"entities\": [{\"text\": \"ketamine\", \"type\": \"Chemical\"}, {\"text\": \"lidocaine\", \"type\": \"Chemical\"}, {\"text\": \"hyperalgesia\", \"type\": \"Disease\"}, {\"text\": \"capsaicin\", \"type\": \"Chemical\"}]}", "n_entities": 4} {"ref": "bc5cdr-train-04632", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Initial cardiopulmonary resuscitation and immediate treatment with adrenaline (epinephrine ), atropine and furosemide was successful.", "completion": "{\"entities\": [{\"text\": \"adrenaline\", \"type\": \"Chemical\"}, {\"text\": \"epinephrine\", \"type\": \"Chemical\"}, {\"text\": \"atropine\", \"type\": \"Chemical\"}, {\"text\": \"furosemide\", \"type\": \"Chemical\"}]}", "n_entities": 4} {"ref": "bc5cdr-train-05013", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In long - term infusion studies, flestolol was well tolerated at the effective beta - blocking dose (5 micrograms / kg / min) for up to seven days.", "completion": "{\"entities\": [{\"text\": \"flestolol\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-04552", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Additional studies of these murine strains may be useful for investigating genetic influences on cocaine - induced seizures", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-05201", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: By day 11, GLEPP1 protein and mRNA had begun to return towards baseline.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-01764", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Eight glaucomatous patients chronically treated with timolol 0.", "completion": "{\"entities\": [{\"text\": \"glaucomatous\", \"type\": \"Disease\"}, {\"text\": \"timolol\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-04051", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: AKBR and biological hepatic function tests showed no change throughout the time course in groups A and B.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-03321", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: n = 9 ]. Proteinuria was measured every 2 weeks.", "completion": "{\"entities\": [{\"text\": \"Proteinuria\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-00853", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Bilateral infusions of neurotensin into the globus pallidus reversed haloperidol - induced parkinsonian catalepsy in rats.", "completion": "{\"entities\": [{\"text\": \"neurotensin\", \"type\": \"Chemical\"}, {\"text\": \"haloperidol\", \"type\": \"Chemical\"}, {\"text\": \"parkinsonian catalepsy\", \"type\": \"Disease\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-04165", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Accordingly, the present, prospective double - blind study compares prilocaine with lidocaine and bupivacaine with respect to duration of action and relative risk of TNSs.", "completion": "{\"entities\": [{\"text\": \"prilocaine\", \"type\": \"Chemical\"}, {\"text\": \"lidocaine\", \"type\": \"Chemical\"}, {\"text\": \"bupivacaine\", \"type\": \"Chemical\"}, {\"text\": \"TNSs\", \"type\": \"Disease\"}]}", "n_entities": 4} {"ref": "bc5cdr-train-04085", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Based on the finding that VPU and VPA could protect the animals against pilocarpine - induced seizure it is suggested that the reduction of inhibitory amino acid neurotransmitters was comparatively minor and offset by a pronounced reduction of glutamate and aspartate.", "completion": "{\"entities\": [{\"text\": \"VPU\", \"type\": \"Chemical\"}, {\"text\": \"VPA\", \"type\": \"Chemical\"}, {\"text\": \"pilocarpine\", \"type\": \"Chemical\"}, {\"text\": \"seizure\", \"type\": \"Disease\"}, {\"text\": \"amino acid\", \"type\": \"Chemical\"}, {\"text\": \"glutamate\", \"type\": \"Chemical\"}, {\"text\": \"aspartate\", \"type\": \"Chemical\"}]}", "n_entities": 7} {"ref": "bc5cdr-train-02492", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 9 (2006 ), 917] recently identified the microglial - specific fractalkine receptor (CX3CR1) as an important mediator of MPTP - induced neurodegeneration of DA neurons.", "completion": "{\"entities\": [{\"text\": \"MPTP\", \"type\": \"Chemical\"}, {\"text\": \"neurodegeneration\", \"type\": \"Disease\"}, {\"text\": \"DA\", \"type\": \"Chemical\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-03043", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: By understanding the underlying mechanism of absence epilepsy, we can avoid the inappropriate use of anticonvulsants in children with epilepsy and prevent drug - induced absence seizures", "completion": "{\"entities\": [{\"text\": \"absence epilepsy\", \"type\": \"Disease\"}, {\"text\": \"epilepsy\", \"type\": \"Disease\"}, {\"text\": \"absence seizures\", \"type\": \"Disease\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-03015", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Granulomatous hepatitis due to combination of amoxicillin and clavulanic acid.", "completion": "{\"entities\": [{\"text\": \"Granulomatous hepatitis\", \"type\": \"Disease\"}, {\"text\": \"combination of amoxicillin and clavulanic acid\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-00667", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 21 mg / dL and thereafter, 4.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-03725", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The area under the curve was 537 +/- 149 ng / ml x hours, volume of distribution (Vd) 3504 +/- 644 l / m2, and total clearance (ClT) was 204 + 39.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-02070", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The cause of hearing loss after spinal anaesthesia is unknown.", "completion": "{\"entities\": [{\"text\": \"hearing loss\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-01975", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In both instances, suspicion of the presence of carcinoma", "completion": "{\"entities\": [{\"text\": \"carcinoma\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-00467", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Treatment for 2 weeks with Warfarin caused massive focal calcification of the artery media in 20 - day - old rats and less extensive focal calcification in 42 - day - old rats.", "completion": "{\"entities\": [{\"text\": \"Warfarin\", \"type\": \"Chemical\"}, {\"text\": \"calcification\", \"type\": \"Disease\"}, {\"text\": \"calcification of the artery\", \"type\": \"Disease\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-02913", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Extracorporeal lithotripsy successfully removed a renal calculus in one patient and surgery removed a staghorn calculus in another, permitting continued treatment.", "completion": "{\"entities\": [{\"text\": \"renal calculus\", \"type\": \"Disease\"}, {\"text\": \"calculus\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-02390", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Serum creatinine (SCr) levels and estimated glomerular filtration rate were assessed at baseline and 2 to 5 days after receiving medications.", "completion": "{\"entities\": [{\"text\": \"creatinine\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-03223", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A low incidence of cardiovascular malformations was observed after exposure to each of the four calcium channel blockers, but this incidence was statistically significant only for verapamil and nifedipine.", "completion": "{\"entities\": [{\"text\": \"cardiovascular malformations\", \"type\": \"Disease\"}, {\"text\": \"calcium\", \"type\": \"Chemical\"}, {\"text\": \"verapamil\", \"type\": \"Chemical\"}, {\"text\": \"nifedipine\", \"type\": \"Chemical\"}]}", "n_entities": 4} {"ref": "bc5cdr-train-00953", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Akathisia appeared to be a common side effect of fluoxetine and generally responded well to treatment with the beta - adrenergic antagonist propranolol, dose reduction, or both.", "completion": "{\"entities\": [{\"text\": \"Akathisia\", \"type\": \"Disease\"}, {\"text\": \"fluoxetine\", \"type\": \"Chemical\"}, {\"text\": \"propranolol\", \"type\": \"Chemical\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-reassigned-00992", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The patient' s renal function remained unaffected.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-04804", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: v .) was examined in mice, rats and guinea pigs by use of the hot - plate, abdominal - constriction, tail - flick and paw - pressure tests .(+/-)- PG-9 antinociception peaked 15 min after injection and then slowly diminished.", "completion": "{\"entities\": [{\"text\": \"PG-9\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-00029", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Newborn female Wistar rats were fed a lithium - containing diet (50 mmol / kg) for 8 weeks and then randomized to normal diet, HP diet (40 vs.", "completion": "{\"entities\": [{\"text\": \"lithium\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-01622", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Our findings indicate that beta2 - adrenoceptor overstimulation during an early critical period results in microglial activation associated with innate neuroinflammatory pathways and behavioral abnormalities, similar to those described in autism.", "completion": "{\"entities\": [{\"text\": \"behavioral abnormalities\", \"type\": \"Disease\"}, {\"text\": \"autism\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-00264", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Diabetes mellitus was the major cause of autonomic neuropathy.", "completion": "{\"entities\": [{\"text\": \"Diabetes mellitus\", \"type\": \"Disease\"}, {\"text\": \"autonomic neuropathy\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-04313", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: p .). A 10 mg / kg dose of LY274614 was effective in antagonizing the depletion of dopamine in the striatum, when given as long as 8 hr prior to amphetamine but not when given 24 hr prior to amphetamine.", "completion": "{\"entities\": [{\"text\": \"LY274614\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}, {\"text\": \"amphetamine\", \"type\": \"Chemical\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-00837", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: During a 9 - year period, we retrospectively collected 27 neurological events (11 %) in as many patients, from 253 children enrolled in the ALL front - line protocol.", "completion": "{\"entities\": [{\"text\": \"ALL\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-00403", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Immunohistochemical studies with antibodies to neurofilament proteins on axonal damage in experimental focal lesions in rat.", "completion": "{\"entities\": [{\"text\": \"axonal damage\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-04389", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Whether proteinuria was due to sirolimus or only a consequence of calcineurin inhibitors withdrawal remained unsolved until high range proteinuria has been observed during sirolimus therapy in islet transplantation and in patients who received sirolimus de novo.", "completion": "{\"entities\": [{\"text\": \"proteinuria\", \"type\": \"Disease\"}, {\"text\": \"sirolimus\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-02302", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Ketoconazole - induced neurologic sequelae.", "completion": "{\"entities\": [{\"text\": \"Ketoconazole\", \"type\": \"Chemical\"}, {\"text\": \"neurologic sequelae\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-03577", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: An analysis is presented of 220 cases of possible neurotoxic reactions to halogenated hydroxyquinolines reported from outside Japan.", "completion": "{\"entities\": [{\"text\": \"neurotoxic\", \"type\": \"Disease\"}, {\"text\": \"halogenated hydroxyquinolines\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-00335", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Reactive oxygen species have been implicated in the pathogenesis of acute puromycin aminonucleoside (PAN )- induced nephropathy, with antioxidants significantly reducing the proteinuria.", "completion": "{\"entities\": [{\"text\": \"oxygen\", \"type\": \"Chemical\"}, {\"text\": \"puromycin aminonucleoside\", \"type\": \"Chemical\"}, {\"text\": \"PAN\", \"type\": \"Chemical\"}, {\"text\": \"nephropathy\", \"type\": \"Disease\"}, {\"text\": \"proteinuria\", \"type\": \"Disease\"}]}", "n_entities": 5} {"ref": "bc5cdr-train-03509", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Monitoring consisted of airflow detection by a carbon dioxide analyser, chest wall movement detected by pneumatic capsules, and continuous electrocardiograph recorded with a Holter ambulatory monitor.", "completion": "{\"entities\": [{\"text\": \"carbon dioxide\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-01233", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Recurarization in the recovery room.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-01382", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: We have demonstrated an increased risk of VTE associated with the use of CPA / EE in women with acne, hirsutism or PCOS", "completion": "{\"entities\": [{\"text\": \"VTE\", \"type\": \"Disease\"}, {\"text\": \"CPA\", \"type\": \"Chemical\"}, {\"text\": \"EE\", \"type\": \"Chemical\"}, {\"text\": \"acne\", \"type\": \"Disease\"}, {\"text\": \"hirsutism\", \"type\": \"Disease\"}, {\"text\": \"PCOS\", \"type\": \"Disease\"}]}", "n_entities": 6} {"ref": "bc5cdr-train-02579", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: Sirolimus is the latest immunosuppressive agent used to prevent rejection, and may have less nephrotoxicity than calcineurin inhibitor (CNI )- based regimens.", "completion": "{\"entities\": [{\"text\": \"Sirolimus\", \"type\": \"Chemical\"}, {\"text\": \"nephrotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-02585", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Laboratory results were compared between prior, during and following sirolimus use.", "completion": "{\"entities\": [{\"text\": \"sirolimus\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-04158", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: DBP, but not SBP, reduction was associated with neurological worsening after the intravenous administration of high - dose nimodipine after acute stroke.", "completion": "{\"entities\": [{\"text\": \"nimodipine\", \"type\": \"Chemical\"}, {\"text\": \"acute stroke\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-00201", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, the level in the AS / KS group remained considerably lower than in the A group.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-04241", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Of the 82 evaluable patients, 50 did not show any recurrence after 1 year (61 %), while 32 presented with one or more recurrences (39 %). Of these recurrences, 27 were T1 tumors while five progressed to more highly invasive lesions.", "completion": "{\"entities\": [{\"text\": \"tumors\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-03847", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Three patients received high doses of chlormethiazole for alcohol withdrawal symptoms, and one took a suicidal overdose of nitrazepam.", "completion": "{\"entities\": [{\"text\": \"chlormethiazole\", \"type\": \"Chemical\"}, {\"text\": \"alcohol\", \"type\": \"Chemical\"}, {\"text\": \"withdrawal symptoms\", \"type\": \"Disease\"}, {\"text\": \"overdose\", \"type\": \"Disease\"}, {\"text\": \"nitrazepam\", \"type\": \"Chemical\"}]}", "n_entities": 5} {"ref": "bc5cdr-train-reassigned-04188", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 01) and thrombophlebitis (93.", "completion": "{\"entities\": [{\"text\": \"thrombophlebitis\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-01974", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: One patient, aged 23, had been followed for 2 years before carcinoma was diagnosed; the second patient, aged 22, had been seen on a regular basis for 5 years, 8 months.", "completion": "{\"entities\": [{\"text\": \"carcinoma\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-03992", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Protective efficacy of neuroactive steroids against cocaine kindled - seizures in mice.", "completion": "{\"entities\": [{\"text\": \"steroids\", \"type\": \"Chemical\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-02962", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: To determine sensitivity we assessed tremor in 44 patients with obstructive lung disease after administration of cumulative doses of salbutamol.", "completion": "{\"entities\": [{\"text\": \"tremor\", \"type\": \"Disease\"}, {\"text\": \"obstructive lung disease\", \"type\": \"Disease\"}, {\"text\": \"salbutamol\", \"type\": \"Chemical\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-03405", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Our observations demonstrated an association of hearing loss with a higher incidence of perinatal complications.", "completion": "{\"entities\": [{\"text\": \"hearing loss\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-00428", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Collaborative Working Group on Clinical Trial Evaluations.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-03287", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 99mTc-glucarate for detection of isoproterenol - induced myocardial infarction in rats.", "completion": "{\"entities\": [{\"text\": \"99mTc-glucarate\", \"type\": \"Chemical\"}, {\"text\": \"isoproterenol\", \"type\": \"Chemical\"}, {\"text\": \"myocardial infarction\", \"type\": \"Disease\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-03362", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Fourteen subjects completed both treatment arms.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-01697", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The glycine transporter - 1 inhibitor SSR103800 displays a selective and specific antipsychotic - like profile in normal and transgenic mice.", "completion": "{\"entities\": [{\"text\": \"glycine\", \"type\": \"Chemical\"}, {\"text\": \"SSR103800\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-04627", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The mode of action was said to be comparable to that of the synthetic compound' carbamylcholin '; that is, carbachol.", "completion": "{\"entities\": [{\"text\": \"carbamylcholin\", \"type\": \"Chemical\"}, {\"text\": \"carbachol\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-04556", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In one patient, reintroduction of FK506 led to rapid recurrence of MAHA.", "completion": "{\"entities\": [{\"text\": \"FK506\", \"type\": \"Chemical\"}, {\"text\": \"MAHA\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-00876", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In addition, reflex bradycardia caused by injected norepinephrine was significantly enhanced by L-dopa, DL-Threo-dihydroxyphenylserine had no effect on blood pressure, heart rate or reflex responses to norepinephrine.", "completion": "{\"entities\": [{\"text\": \"bradycardia\", \"type\": \"Disease\"}, {\"text\": \"norepinephrine\", \"type\": \"Chemical\"}, {\"text\": \"L-dopa\", \"type\": \"Chemical\"}, {\"text\": \"DL-Threo-dihydroxyphenylserine\", \"type\": \"Chemical\"}]}", "n_entities": 4} {"ref": "bc5cdr-train-00027", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Effects of uninephrectomy and high protein feeding on lithium - induced chronic renal failure in rats.", "completion": "{\"entities\": [{\"text\": \"lithium\", \"type\": \"Chemical\"}, {\"text\": \"chronic renal failure\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-04076", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In addition, mitochondrial respiratory dysfunction characterized by decreased respiratory control ratio and ADP / O was observed in isoproterenol - treated rats.", "completion": "{\"entities\": [{\"text\": \"respiratory dysfunction\", \"type\": \"Disease\"}, {\"text\": \"ADP\", \"type\": \"Chemical\"}, {\"text\": \"isoproterenol\", \"type\": \"Chemical\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-04829", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 47 mg) was always administered in one single dose.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-00113", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It is suggested that the effects of Captopril on the lungs may be attributable to a vasodilatory effect due to a reduction in the circulating level of Angiotension II and an increase in prostacyclin (secondary to an increase in bradykinin ). Captopril may, by the same mechanism, reduce the increase in glomerular filtration that is known to occur after an injection of thrombin, thereby diminishing the aggregation of fibrin monomers in the glomeruli, with the result that less fibrin will be deposited and thus less kidney damage", "completion": "{\"entities\": [{\"text\": \"Captopril\", \"type\": \"Chemical\"}, {\"text\": \"Angiotension II\", \"type\": \"Chemical\"}, {\"text\": \"prostacyclin\", \"type\": \"Chemical\"}, {\"text\": \"bradykinin\", \"type\": \"Chemical\"}, {\"text\": \"kidney damage\", \"type\": \"Disease\"}]}", "n_entities": 5} {"ref": "bc5cdr-train-00297", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Characterization of estrogen - induced adenohypophyseal tumors in the Fischer 344 rat.", "completion": "{\"entities\": [{\"text\": \"estrogen\", \"type\": \"Chemical\"}, {\"text\": \"adenohypophyseal tumors\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-00189", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Manic excitement was coincident with the duration of action of triazolam.", "completion": "{\"entities\": [{\"text\": \"Manic\", \"type\": \"Disease\"}, {\"text\": \"triazolam\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-02038", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: They became more severe in the later months of the experiment, and were most severe after 12 months, located mainly in the molecular layer of the cerebellar cortex.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-03413", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: change on cimetidine and 6 had moderate to severe changes.", "completion": "{\"entities\": [{\"text\": \"cimetidine\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-01348", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We also used microdialysis to measure basal and potassium - stimulated acetylcholine (ACh) release in the CA1 region of the hippocampus.", "completion": "{\"entities\": [{\"text\": \"potassium\", \"type\": \"Chemical\"}, {\"text\": \"acetylcholine\", \"type\": \"Chemical\"}, {\"text\": \"ACh\", \"type\": \"Chemical\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-01722", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 9 l min (- 1 )). The administration of ephedrine led to a similar increase in MAP (53 +/- 9 to 79 +/- 8 mmHg; P < 0.", "completion": "{\"entities\": [{\"text\": \"ephedrine\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-01043", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Busulfan - induced hemorrhagic cystitis.", "completion": "{\"entities\": [{\"text\": \"Busulfan\", \"type\": \"Chemical\"}, {\"text\": \"hemorrhagic cystitis\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-03053", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Role of activation of bradykinin B2 receptors in disruption of the blood - brain barrier during acute hypertension.", "completion": "{\"entities\": [{\"text\": \"bradykinin\", \"type\": \"Chemical\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-02983", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: STUDY OBJECTIVE: To evaluate the frequency of venous thromboembolism (VTE) in patients with advanced androgen - independent prostate cancer who were treated with docetaxel alone or in combination with thalidomide.", "completion": "{\"entities\": [{\"text\": \"venous thromboembolism\", \"type\": \"Disease\"}, {\"text\": \"VTE\", \"type\": \"Disease\"}, {\"text\": \"prostate cancer\", \"type\": \"Disease\"}, {\"text\": \"docetaxel\", \"type\": \"Chemical\"}, {\"text\": \"thalidomide\", \"type\": \"Chemical\"}]}", "n_entities": 5} {"ref": "bc5cdr-train-05188", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A marker of acute podocyte injury.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-03833", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: As wider use confirms their safety profile, they will gain increasing importance in the therapeutic approach to hypercholesterolaemia", "completion": "{\"entities\": [{\"text\": \"hypercholesterolaemia\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-04551", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Additionally, levels of cocaine determined in hippocampus and cortex were not different between sensitive and resistant strains.", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-00000", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Naloxone reverses the antihypertensive effect of clonidine.", "completion": "{\"entities\": [{\"text\": \"Naloxone\", \"type\": \"Chemical\"}, {\"text\": \"clonidine\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-03681", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Data on the possible increased risk of malignancy in rheumatoid arthritis are still being collected, and until further information is available, the use of immunosuppressive drugs, particularly alkylating agents, in the treatment of rheumatoid arthritis", "completion": "{\"entities\": [{\"text\": \"malignancy\", \"type\": \"Disease\"}, {\"text\": \"rheumatoid arthritis\", \"type\": \"Disease\"}, {\"text\": \"alkylating agents\", \"type\": \"Chemical\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-00192", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The development of tolerance to the muscular rigidity produced by morphine was studied in rats.", "completion": "{\"entities\": [{\"text\": \"muscular rigidity\", \"type\": \"Disease\"}, {\"text\": \"morphine\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-00061", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We studied a 37 - year - old man who developed persistent segmental dystonia within 2 months after starting sulpiride therapy.", "completion": "{\"entities\": [{\"text\": \"dystonia\", \"type\": \"Disease\"}, {\"text\": \"sulpiride\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-04951", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Only 1 prolactinoma was discovered.", "completion": "{\"entities\": [{\"text\": \"prolactinoma\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-01882", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the present study, cis-platin (80 - 120 mg / m2BSA) and 5-FU (1000 mg / m2BSA daily as a continuous infusion during 5 days) were given to 76 patients before radiotherapy and surgery.", "completion": "{\"entities\": [{\"text\": \"cis-platin\", \"type\": \"Chemical\"}, {\"text\": \"5-FU\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-00586", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Platelet serotonin content decreased significantly (P < 0.", "completion": "{\"entities\": [{\"text\": \"serotonin\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-00704", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: For the first few days after ingestion, she was in a confused state and had mild to moderate ataxia and giddiness.", "completion": "{\"entities\": [{\"text\": \"ataxia\", \"type\": \"Disease\"}, {\"text\": \"giddiness\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-03857", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: This double - blind study examined the incidence and severity of postoperative nausea and vomiting and pain in the first 24 h after sevoflurane anaesthesia in 216 adult day surgery patients.", "completion": "{\"entities\": [{\"text\": \"postoperative nausea and vomiting\", \"type\": \"Disease\"}, {\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"sevoflurane\", \"type\": \"Chemical\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-03388", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Corticosteroids different from paramethasone also produced hypersensitivity reactions in these patients; however, a few of them were tolerated.", "completion": "{\"entities\": [{\"text\": \"paramethasone\", \"type\": \"Chemical\"}, {\"text\": \"hypersensitivity\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-04784", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Hemoglobin levels also decreased but insignificantly by treatment.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-02559", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Urinary volume and serum creatinine levels recovered to the normal range, with urinary protein disappearing completely within 40 days.", "completion": "{\"entities\": [{\"text\": \"creatinine\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-01973", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Two cases of clear cell adenocarcinoma of the vagina detected at follow - up in young women exposed in utero to diethylstilbestrol are reported.", "completion": "{\"entities\": [{\"text\": \"clear cell adenocarcinoma of the vagina\", \"type\": \"Disease\"}, {\"text\": \"diethylstilbestrol\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-03400", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: While the involvement of metronidazole in the aetiology of the haemolytic-uraemic syndrome is not established firmly, the action of this drug in sensitizing tissues to oxidation injury and the reported evidence of oxidation changes in the haemolytic-uraemic syndrome suggest a possible link between metronidazole treatment and some cases of the haemolytic-uraemic syndrome", "completion": "{\"entities\": [{\"text\": \"metronidazole\", \"type\": \"Chemical\"}, {\"text\": \"haemolytic-uraemic syndrome\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-00030", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 19 %), NX or HP + NX for another 8 weeks.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-01576", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It has also been suggested that sirolimus directly causes increased glomerular permeability / injury, but evidence for this mechanism is currently inconclusive.", "completion": "{\"entities\": [{\"text\": \"sirolimus\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-04456", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Causes of acute thrombotic microangiopathy in patients receiving kidney transplantation.", "completion": "{\"entities\": [{\"text\": \"thrombotic microangiopathy\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-04947", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The prevalence of repeatedly low testosterone increased with age (4% before age 50 years and 9% 50 years or older ). Two pituitary tumors were discovered after testosterone determination.", "completion": "{\"entities\": [{\"text\": \"testosterone\", \"type\": \"Chemical\"}, {\"text\": \"pituitary tumors\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-00411", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Depression is a major clinical feature of Parkinson's disease.", "completion": "{\"entities\": [{\"text\": \"Depression\", \"type\": \"Disease\"}, {\"text\": \"Parkinson's disease\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-02720", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: As the most potent dose (1 mg / kg) of lipopolysaccharide was administered two weeks, one day before or after the methamphetamine dosing regimen, methamphetamine - induced striatal dopamine and 3,4-dihydroxyphenylacetic acid depletions remained unaltered.", "completion": "{\"entities\": [{\"text\": \"lipopolysaccharide\", \"type\": \"Chemical\"}, {\"text\": \"methamphetamine\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}, {\"text\": \"3,4-dihydroxyphenylacetic acid\", \"type\": \"Chemical\"}]}", "n_entities": 4} {"ref": "bc5cdr-train-04357", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 4 %; P: 6 / 20 = 30 %). This pilot study leads to the conclusion that glutamate supplementation at the chosen regimen fails to protect against peripheral neurotoxicity of PAC", "completion": "{\"entities\": [{\"text\": \"glutamate\", \"type\": \"Chemical\"}, {\"text\": \"peripheral neurotoxicity\", \"type\": \"Disease\"}, {\"text\": \"PAC\", \"type\": \"Chemical\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-02972", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Tremor was measured simultaneously by two independent observers.", "completion": "{\"entities\": [{\"text\": \"Tremor\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-02563", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The aldosterone - sensitive serum - and glucocorticoid - inducible kinase SGK1 has been shown to participate in the stimulation of ENaC and to mediate renal fibrosis following mineralocorticoid and salt excess.", "completion": "{\"entities\": [{\"text\": \"aldosterone\", \"type\": \"Chemical\"}, {\"text\": \"fibrosis\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-reassigned-02412", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In patients with downbeat nystagmus", "completion": "{\"entities\": [{\"text\": \"downbeat nystagmus\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-03576", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Neurotoxicity of halogenated hydroxyquinolines: clinical analysis of cases reported outside Japan.", "completion": "{\"entities\": [{\"text\": \"Neurotoxicity\", \"type\": \"Disease\"}, {\"text\": \"halogenated hydroxyquinolines\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-04960", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thiopentone pretreatment for propofol injection pain in ambulatory patients.", "completion": "{\"entities\": [{\"text\": \"Thiopentone\", \"type\": \"Chemical\"}, {\"text\": \"propofol\", \"type\": \"Chemical\"}, {\"text\": \"pain\", \"type\": \"Disease\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-02000", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Side - effects tended to diminish during treatment but remained significant at week 8.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-03178", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Decreases in systolic blood pressure were statistically, but not clinically, significant.", "completion": "{\"entities\": [{\"text\": \"Decreases in systolic blood pressure\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-03611", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Beginning on day 22, all rats were maintained on ad libitum chow.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-03821", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Lovastatin and simvastatin are the 2 best - known members of the class of hypolipidaemic agents known as HMG CoA reductase inhibitors.", "completion": "{\"entities\": [{\"text\": \"Lovastatin\", \"type\": \"Chemical\"}, {\"text\": \"simvastatin\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-01997", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Mean alprazolam dose was 5 mg daily.", "completion": "{\"entities\": [{\"text\": \"alprazolam\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-02754", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The duration of action may be prolonged in patients with genetic variants of the butyrylcholinesterase enzyme (BChE ), the most common being the K - and the A - variants.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-02410", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 37 ). Mean post - SCr increases were significantly less with iopamidol (all patients: 0.", "completion": "{\"entities\": [{\"text\": \"iopamidol\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-02764", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSION: eleven of 13 patients with a prolonged duration of action of succinylcholine had mutations in BCHE, indicating that this is the possible reason for a prolonged period of apnea", "completion": "{\"entities\": [{\"text\": \"succinylcholine\", \"type\": \"Chemical\"}, {\"text\": \"apnea\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-01449", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Tincture of Crataegus (TCR ), an alcoholic extract of the berries of hawthorn (Crataegus oxycantha ), is used in herbal and homeopathic medicine.", "completion": "{\"entities\": [{\"text\": \"Tincture of Crataegus\", \"type\": \"Chemical\"}, {\"text\": \"TCR\", \"type\": \"Chemical\"}, {\"text\": \"alcoholic extract of the berries of hawthorn\", \"type\": \"Chemical\"}, {\"text\": \"Crataegus oxycantha\", \"type\": \"Chemical\"}]}", "n_entities": 4} {"ref": "bc5cdr-train-03184", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Organic mental disorder was observed in a 29 - year - old female in the prognostic period after the onset of carmofur - induced leukoencephalopathy.", "completion": "{\"entities\": [{\"text\": \"Organic mental disorder\", \"type\": \"Disease\"}, {\"text\": \"carmofur\", \"type\": \"Chemical\"}, {\"text\": \"leukoencephalopathy\", \"type\": \"Disease\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-01632", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It can be fatal if not recognized and treated early.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-00347", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Plasma PRL concentrations were analysed at 10 min intervals and underlying secretory rates calculated by a deconvolution procedure.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-04525", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We observed the exencephaly induced by 5-azacytidine at embryonic day 13.", "completion": "{\"entities\": [{\"text\": \"exencephaly\", \"type\": \"Disease\"}, {\"text\": \"5-azacytidine\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-02846", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 001) without any difference within or across sessions.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-reassigned-01746", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Blood pressure effects of i.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-01095", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: DISCUSSION: After most infections causing erythema multiforme and myocarditis were ruled out, a drug-induced allergic reaction was suspected.", "completion": "{\"entities\": [{\"text\": \"infections\", \"type\": \"Disease\"}, {\"text\": \"erythema multiforme\", \"type\": \"Disease\"}, {\"text\": \"myocarditis\", \"type\": \"Disease\"}, {\"text\": \"drug-induced allergic reaction\", \"type\": \"Disease\"}]}", "n_entities": 4} {"ref": "bc5cdr-train-04322", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Nitroglycerin has been shown to reduce ST - segment elevation during acute myocardial infarction, an effect potentiated in the dog by agents that reverse nitroglycerin - induced hypotension.", "completion": "{\"entities\": [{\"text\": \"Nitroglycerin\", \"type\": \"Chemical\"}, {\"text\": \"acute myocardial infarction\", \"type\": \"Disease\"}, {\"text\": \"nitroglycerin\", \"type\": \"Chemical\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}]}", "n_entities": 4} {"ref": "bc5cdr-train-02378", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Luke' s Hospital, Gwardamangia, Malta.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-02833", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A lesser degree of orthostatic hypotension occurred with standing.", "completion": "{\"entities\": [{\"text\": \"orthostatic hypotension\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-03025", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Age at presentation, time of ictus after intoxication, Hunt and Hess grade of subarachnoid hemorrhage, size of the aneurysm, location of the aneurysm, and the Glasgow Outcome Scale score were assessed and compared.", "completion": "{\"entities\": [{\"text\": \"subarachnoid hemorrhage\", \"type\": \"Disease\"}, {\"text\": \"aneurysm\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-02409", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 2 %, respectively (P = 0.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-04852", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Both, production of reactive oxygen species as well as activation of NF - kappaB have been implicated in severe neuronal damage in different sub - regions of the hippocampus as well as in the surrounding cortices.", "completion": "{\"entities\": [{\"text\": \"oxygen\", \"type\": \"Chemical\"}, {\"text\": \"neuronal damage\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-03169", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: There was one treatment - related death.", "completion": "{\"entities\": [{\"text\": \"death\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-00465", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The present studies demonstrate that growth and vitamin D treatment enhance the extent of artery calcification in rats given sufficient doses of Warfarin to inhibit gamma - carboxylation of matrix Gla protein, a calcification inhibitor known to be expressed by smooth muscle cells and macrophages in the artery wall.", "completion": "{\"entities\": [{\"text\": \"vitamin D\", \"type\": \"Chemical\"}, {\"text\": \"artery calcification\", \"type\": \"Disease\"}, {\"text\": \"calcification\", \"type\": \"Disease\"}, {\"text\": \"Warfarin\", \"type\": \"Chemical\"}]}", "n_entities": 4} {"ref": "bc5cdr-train-02050", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: Although intravitreal aminoglycosides have substantially improved visual prognosis in endophthalmitis, macular infarction may impair full visual recovery.", "completion": "{\"entities\": [{\"text\": \"aminoglycosides\", \"type\": \"Chemical\"}, {\"text\": \"endophthalmitis\", \"type\": \"Disease\"}, {\"text\": \"infarction\", \"type\": \"Disease\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-03991", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Prenatal exposure to selective COX - 2 inhibitors does not increase the risk of ventricular septal and midline defects", "completion": "{\"entities\": [{\"text\": \"ventricular septal and midline defects\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-00872", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Mediation of enhanced reflex vagal bradycardia by L-dopa via central dopamine formation in dogs.", "completion": "{\"entities\": [{\"text\": \"bradycardia\", \"type\": \"Disease\"}, {\"text\": \"L-dopa\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-01600", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Influence of smoking on developing cochlea.", "completion": "{\"entities\": [{\"text\": \"smoking\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-01620", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: of these effects occurred in animals given terbutaline on PN 11 to 14.", "completion": "{\"entities\": [{\"text\": \"terbutaline\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-03937", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We have described a unique patient who had reversible and dose - related myasthenia gravis after penicillamine and chloroquine therapy for rheumatoid arthritis.", "completion": "{\"entities\": [{\"text\": \"myasthenia gravis\", \"type\": \"Disease\"}, {\"text\": \"penicillamine\", \"type\": \"Chemical\"}, {\"text\": \"chloroquine\", \"type\": \"Chemical\"}, {\"text\": \"rheumatoid arthritis\", \"type\": \"Disease\"}]}", "n_entities": 4} {"ref": "bc5cdr-train-01617", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We studied the effects of terbutaline on microglial activation in different brain regions and behavioral outcomes in developing rats.", "completion": "{\"entities\": [{\"text\": \"terbutaline\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-03449", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Subjects with SNHL were submitted to DFO reduction or temporary withdrawal.", "completion": "{\"entities\": [{\"text\": \"SNHL\", \"type\": \"Disease\"}, {\"text\": \"DFO\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-00528", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5) among those who used third - generation oral contraceptives.", "completion": "{\"entities\": [{\"text\": \"oral contraceptives\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-00022", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Fasciculations in the six areas and the total fasciculation score were related directly to the rate of infusion.", "completion": "{\"entities\": [{\"text\": \"Fasciculations\", \"type\": \"Disease\"}, {\"text\": \"fasciculation\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-00455", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Eastern Cooperative Oncology Group performance status improved in 35% of those patients with an initial value > 0, whereas relief of at least 1 symptom without worsening of other symptoms was noted in 27 patients (55 %). The median time to progression was 16 weeks and the 1 - year survival rate was 33 %. Toxicity was mild.", "completion": "{\"entities\": [{\"text\": \"Toxicity\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-00184", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Therefore, patients belonging to the poor - metabolizer phenotype of sparteine / debrisoquine polymorphism in drug metabolism, which constitutes 6.", "completion": "{\"entities\": [{\"text\": \"sparteine\", \"type\": \"Chemical\"}, {\"text\": \"debrisoquine\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-04798", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Antinociceptive and antiamnesic properties of the presynaptic cholinergic amplifier PG-9.", "completion": "{\"entities\": [{\"text\": \"PG-9\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-02448", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Sex differences in NMDA antagonist enhancement of morphine antihyperalgesia in a capsaicin model of persistent pain: comparisons to two models of acute pain.", "completion": "{\"entities\": [{\"text\": \"NMDA\", \"type\": \"Chemical\"}, {\"text\": \"morphine\", \"type\": \"Chemical\"}, {\"text\": \"capsaicin\", \"type\": \"Chemical\"}, {\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"acute pain\", \"type\": \"Disease\"}]}", "n_entities": 5} {"ref": "bc5cdr-train-01506", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Plasma TAFI, tPA, and PAI - 1 antigen levels were measured at baseline and after 3 months of treatment by commercially available ELISA kits.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-02389", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS AND RESULTS: The present study is a multicenter, randomized, double - blind comparison of iopamidol and iodixanol in patients with chronic kidney disease (estimated glomerular filtration rate, 20 to 59 mL / min) who underwent cardiac angiography or percutaneous coronary interventions.", "completion": "{\"entities\": [{\"text\": \"iopamidol\", \"type\": \"Chemical\"}, {\"text\": \"iodixanol\", \"type\": \"Chemical\"}, {\"text\": \"chronic kidney disease\", \"type\": \"Disease\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-00673", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Whether or not the neuronal transmission may be affected by cystitis was presently investigated.", "completion": "{\"entities\": [{\"text\": \"cystitis\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-00955", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Chronic active hepatitis associated with diclofenac sodium therapy.", "completion": "{\"entities\": [{\"text\": \"Chronic active hepatitis\", \"type\": \"Disease\"}, {\"text\": \"diclofenac sodium\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-00893", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The finding of cocaine - induced vasoconstriction in segments of (noninnervated) human umbilical artery suggests that the presence or absence of intact innervation is not sufficient to explain the discrepant data involving the possibility of alpha - mediated effects.", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-00340", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Tissue lipid peroxidation was measured in whole homogenates as well as in lipid extracts from homogenates as thiobarbituric acid reactive substances.", "completion": "{\"entities\": [{\"text\": \"thiobarbituric acid\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-00431", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The side effect profiles of the atypical antipsychotics are more advantageous than those of the conventional neuroleptics.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-03194", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The primary response variable was based on central reading of 24 hour ambulatory electrocardiographic recordings and was defined as the occurrence of 30 or more single premature ventricular complexes in any two consecutive 30 minute blocks or one or more runs of two or more premature ventricular complexes in the entire 24 hour electrocardiographic recording.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-05049", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Peripheral neuropathy has been noted as a complication of therapy with perhexiline maleate, a drug widely used in France (and in clinical trials in the United States) for the prophylactic treatment of angina pectoris.", "completion": "{\"entities\": [{\"text\": \"Peripheral neuropathy\", \"type\": \"Disease\"}, {\"text\": \"perhexiline maleate\", \"type\": \"Chemical\"}, {\"text\": \"angina pectoris\", \"type\": \"Disease\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-02643", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Nephrin decreased further, while dendrin and plekhh2 also decreased but a - actinin remained unchanged.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-01164", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This report summarizes our experience in switching bipolar patients from lithium to divalproex sodium to alleviate such cognitive and functional impairments.", "completion": "{\"entities\": [{\"text\": \"bipolar\", \"type\": \"Disease\"}, {\"text\": \"lithium\", \"type\": \"Chemical\"}, {\"text\": \"divalproex sodium\", \"type\": \"Chemical\"}, {\"text\": \"cognitive and functional impairments\", \"type\": \"Disease\"}]}", "n_entities": 4} {"ref": "bc5cdr-train-02794", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Prophylactic administration of lamivudine", "completion": "{\"entities\": [{\"text\": \"lamivudine\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-00525", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 1) among women who used second - generation oral contraceptives and 1.", "completion": "{\"entities\": [{\"text\": \"oral contraceptives\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-04323", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Our study was designed to determine the effects of combined nitroglycerin and phenylephrine therapy.", "completion": "{\"entities\": [{\"text\": \"nitroglycerin\", \"type\": \"Chemical\"}, {\"text\": \"phenylephrine\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-02087", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: No other risk factors for CNS toxicity were identified.", "completion": "{\"entities\": [{\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-03566", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pain was not explained by other diseases causing foot pain, like reflex sympathetic dystrophy, polyneuropathy, Morton's neuralgia, gout, osteoporosis, avascular necrosis, intermittent claudication, orthopaedic foot deformities, stress fractures, and hyperparathyroidism.", "completion": "{\"entities\": [{\"text\": \"Pain\", \"type\": \"Disease\"}, {\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"reflex sympathetic dystrophy\", \"type\": \"Disease\"}, {\"text\": \"polyneuropathy\", \"type\": \"Disease\"}, {\"text\": \"Morton's neuralgia\", \"type\": \"Disease\"}, {\"text\": \"gout\", \"type\": \"Disease\"}, {\"text\": \"osteoporosis\", \"type\": \"Disease\"}, {\"text\": \"avascular necrosis\", \"type\": \"Disease\"}, {\"text\": \"intermittent claudication\", \"type\": \"Disease\"}, {\"text\": \"foot deformities\", \"type\": \"Disease\"}, {\"text\": \"stress fractures\", \"type\": \"Disease\"}, {\"text\": \"hyperparathyroidism\", \"type\": \"Disease\"}]}", "n_entities": 12} {"ref": "bc5cdr-train-00116", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Each patient was subjected to an identical anesthetic protocol and similar drug - induced reductions in mean arterial blood pressure (BP )(50 to 55 mmHg ). Nitroprusside infusion was associated with a significant (p less than 0.", "completion": "{\"entities\": [{\"text\": \"reductions in mean arterial blood pressure\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-03968", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Exogenous creatine is used by athletes to theoretically improve exercise performance.", "completion": "{\"entities\": [{\"text\": \"creatine\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-04686", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Because each patient was tumor - free or had only a small tumor at the onset of this syndrome, the thrombotic microangiopathy may have been induced by chemotherapy.", "completion": "{\"entities\": [{\"text\": \"tumor\", \"type\": \"Disease\"}, {\"text\": \"thrombotic microangiopathy\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-02785", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Eleven patients (six male) with median age 47 years (range 27 - 73 ), median disease duration 50 months (range 9 - 178) and median follow - up period of patients 13.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-00698", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Acute vocal fold palsy after acute disulfiram intoxication.", "completion": "{\"entities\": [{\"text\": \"vocal fold palsy\", \"type\": \"Disease\"}, {\"text\": \"disulfiram\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-04054", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Levodopa - induced dyskinesias in patients with Parkinson's disease: filling the bench - to - bedside gap.", "completion": "{\"entities\": [{\"text\": \"Levodopa\", \"type\": \"Chemical\"}, {\"text\": \"dyskinesias\", \"type\": \"Disease\"}, {\"text\": \"Parkinson's disease\", \"type\": \"Disease\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-00885", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cocaine - induced myocardial infarction: clinical observations and pathogenetic considerations.", "completion": "{\"entities\": [{\"text\": \"Cocaine\", \"type\": \"Chemical\"}, {\"text\": \"myocardial infarction\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-02661", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The possibility that the intraarterial lesions might represent independent primary tumors", "completion": "{\"entities\": [{\"text\": \"intraarterial lesions\", \"type\": \"Disease\"}, {\"text\": \"tumors\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-02379", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: A double - blind double - armed prospective study comprised 40 patients who had uneventful sutureless phacoemulsification under sub - Tenon' s local infiltration of 3 mL of plain lignocaine.", "completion": "{\"entities\": [{\"text\": \"lignocaine\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-04225", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The purpose of this study was to evaluate the neurologic consequences of deliberate subarachnoid injection of large volumes of 2-chloroprocaine-CE in experimental animals.", "completion": "{\"entities\": [{\"text\": \"2-chloroprocaine-CE\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-02695", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Her aminotransferase levels returned to normal by postoperative day 23, and her 2 - year follow - up showed no adverse events.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-04455", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Although evidences of mitochondrial abnormalities", "completion": "{\"entities\": [{\"text\": \"mitochondrial abnormalities\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-00504", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Myocardial histologic features were analyzed semiquantitatively and results were confirmed by transmission electron microscopy.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-03027", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 002 ). In patients in the study group, all aneurysms were located in the anterior circulation.", "completion": "{\"entities\": [{\"text\": \"aneurysms\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-02381", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 mL of methylprednisolone and 10 mg / 0.", "completion": "{\"entities\": [{\"text\": \"methylprednisolone\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-03374", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: To this day, transcriptome analysis has been performed in a rat model of LID [Neurobiol.", "completion": "{\"entities\": [{\"text\": \"LID\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-04649", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Crossover comparison of efficacy and preference for rizatriptan 10 mg versus ergotamine / caffeine in migraine.", "completion": "{\"entities\": [{\"text\": \"rizatriptan\", \"type\": \"Chemical\"}, {\"text\": \"ergotamine\", \"type\": \"Chemical\"}, {\"text\": \"caffeine\", \"type\": \"Chemical\"}, {\"text\": \"migraine\", \"type\": \"Disease\"}]}", "n_entities": 4} {"ref": "bc5cdr-train-01544", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Spread of the contrast medium within the epidural space was determined by radiographic imaging.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-02370", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Of the 59 cases, 26 (44 %) had a fatal outcome, compared to 136 (25 %) among the non - warfarin patients (p < 0.", "completion": "{\"entities\": [{\"text\": \"warfarin\", \"type\": \"Chemical\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-00302", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 3 times control yields at 8 days of treatment to 58.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-00358", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: During the first day of hospitalization (while intubated ), intravenous metoprolol was given, resulting in severe angioedema.", "completion": "{\"entities\": [{\"text\": \"metoprolol\", \"type\": \"Chemical\"}, {\"text\": \"angioedema\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-00862", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pulmonary shunt and cardiovascular responses to CPAP during nitroprusside - induced hypotension.", "completion": "{\"entities\": [{\"text\": \"nitroprusside\", \"type\": \"Chemical\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-00406", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Infarcts in substantia nigra pars reticulata were evoked by prolonged pilocarpine - induced status epilepticus.", "completion": "{\"entities\": [{\"text\": \"Infarcts in substantia nigra pars reticulata\", \"type\": \"Disease\"}, {\"text\": \"pilocarpine\", \"type\": \"Chemical\"}, {\"text\": \"status epilepticus\", \"type\": \"Disease\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-00702", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Co ., Ansan, Korea) in a suicide attempt.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-03914", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A Phase II trial of cisplatin plus WR-2721 (amifostine) for metastatic breast carcinoma: an Eastern Cooperative Oncology Group Study (E8188 ). BACKGROUND: Cisplatin has minimal antitumor activity when used as second - or third - line treatment of metastatic breast carcinoma.", "completion": "{\"entities\": [{\"text\": \"cisplatin\", \"type\": \"Chemical\"}, {\"text\": \"WR-2721\", \"type\": \"Chemical\"}, {\"text\": \"amifostine\", \"type\": \"Chemical\"}, {\"text\": \"breast carcinoma\", \"type\": \"Disease\"}, {\"text\": \"Cisplatin\", \"type\": \"Chemical\"}]}", "n_entities": 5} {"ref": "bc5cdr-train-03427", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Hepatocyte tight junctions (TJs ), the only intercellular barrier between the sinusoidal and the canalicular spaces, play a key role in bile formation.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-01353", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, the increase in release of ACh produced by the first application of KCl was 2 - fold higher in WSP versus WSR mice.", "completion": "{\"entities\": [{\"text\": \"ACh\", \"type\": \"Chemical\"}, {\"text\": \"KCl\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-03368", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 3 hs ). The t (max) was similar between the regimens.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-00884", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Furthermore, the effects are mediated through dopamine rather than norepinephrine", "completion": "{\"entities\": [{\"text\": \"dopamine\", \"type\": \"Chemical\"}, {\"text\": \"norepinephrine\", \"type\": \"Chemical\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-03778", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The concomitant administration of etoposide and cyclosporin A resulted in eradication of hitherto refractory leukemic infiltration of bone marrow.", "completion": "{\"entities\": [{\"text\": \"etoposide\", \"type\": \"Chemical\"}, {\"text\": \"cyclosporin A\", \"type\": \"Chemical\"}, {\"text\": \"leukemic infiltration\", \"type\": \"Disease\"}]}", "n_entities": 3} {"ref": "bc5cdr-train-03416", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 25 microgram / ml (P less than 0.", "completion": "{\"entities\": []}", "n_entities": 0} {"ref": "bc5cdr-train-03872", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Lamivudine was added because of de nova hepatitis B infection during her follow - up.", "completion": "{\"entities\": [{\"text\": \"Lamivudine\", \"type\": \"Chemical\"}, {\"text\": \"hepatitis B infection\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-02961", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: Tremor was measured using a laser pointer technique.", "completion": "{\"entities\": [{\"text\": \"Tremor\", \"type\": \"Disease\"}]}", "n_entities": 1} {"ref": "bc5cdr-train-04682", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thrombotic microangiopathy and renal failure associated with antineoplastic chemotherapy.", "completion": "{\"entities\": [{\"text\": \"Thrombotic microangiopathy\", \"type\": \"Disease\"}, {\"text\": \"renal failure\", \"type\": \"Disease\"}]}", "n_entities": 2} {"ref": "bc5cdr-train-02380", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: At the end of the procedure, Group A (n = 20) had 20 mg / 0.", "completion": "{\"entities\": []}", "n_entities": 0}