{"ref": "bc5cdr-train-01834", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 002 ). Neither dose of pentoxifylline significantly decreased the dipyridamole - induced hyperemia, while peak coronary blood flow was significantly lower after theophylline (p less than 0.", "completion": "{\"entities\": [{\"text\": \"pentoxifylline\", \"type\": \"Chemical\"}, {\"text\": \"dipyridamole\", \"type\": \"Chemical\"}, {\"text\": \"hyperemia\", \"type\": \"Disease\"}, {\"text\": \"theophylline\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00389", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: min - 1 of TMP (15 patients) was administered intravenously after the dural opening and the dose was adjusted to maintain the mean arterial blood pressure (MAP) at about 60 mmHg.", "completion": "{\"entities\": [{\"text\": \"TMP\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01179", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The overall objective response rate was 7.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00583", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In addition, both change and peak, showed significant positive correlations with migraine headache intensity (P < 0.", "completion": "{\"entities\": [{\"text\": \"migraine\", \"type\": \"Disease\"}, {\"text\": \"headache\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03019", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: As penicillin derivatives and amoxicillin alone are known to induce such types of lesions, the amoxicillin component, with or without a potentiating effect of clavulanic acid", "completion": "{\"entities\": [{\"text\": \"penicillin\", \"type\": \"Chemical\"}, {\"text\": \"amoxicillin\", \"type\": \"Chemical\"}, {\"text\": \"clavulanic acid\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04458", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In postrenal transplantation, thrombotic microangiopathy is often a reflection of hemolytic uremic syndrome.", "completion": "{\"entities\": [{\"text\": \"thrombotic microangiopathy\", \"type\": \"Disease\"}, {\"text\": \"hemolytic uremic syndrome\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05022", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Adverse effect of the calcium channel blocker nitrendipine on nephrosclerosis in rats with renovascular hypertension.", "completion": "{\"entities\": [{\"text\": \"calcium\", \"type\": \"Chemical\"}, {\"text\": \"nitrendipine\", \"type\": \"Chemical\"}, {\"text\": \"nephrosclerosis\", \"type\": \"Disease\"}, {\"text\": \"renovascular hypertension\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03659", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 4 ). Nitrofurantoins were associated with anophthalmia or microphthalmos (AOR = 3.", "completion": "{\"entities\": [{\"text\": \"Nitrofurantoins\", \"type\": \"Chemical\"}, {\"text\": \"anophthalmia\", \"type\": \"Disease\"}, {\"text\": \"microphthalmos\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-05001", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A patient who allegedly consumed 100 tablets of an over - the - counter analgesic containing sodium acetylsalicylate, caffeine, and acetaminophen displayed no significant CNS stimulation despite the presence of 175 micrograms of caffeine per mL of serum.", "completion": "{\"entities\": [{\"text\": \"sodium acetylsalicylate\", \"type\": \"Chemical\"}, {\"text\": \"caffeine\", \"type\": \"Chemical\"}, {\"text\": \"acetaminophen\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03128", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Simvastatin, amiodarone, and the patient' s human immunodeficiency virus medications were all temporarily discontinued and the patient was given forced alkaline diuresis and started on dialysis.", "completion": "{\"entities\": [{\"text\": \"Simvastatin\", \"type\": \"Chemical\"}, {\"text\": \"amiodarone\", \"type\": \"Chemical\"}, {\"text\": \"human immunodeficiency virus\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01507", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Variations of individuals were assessed by Wilcoxon' s test.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00202", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The results suggest that rigidity, which is assumed to be due to an action of morphine in the striatum, can be antagonized by another process leading to dopaminergic activation in the striatum.", "completion": "{\"entities\": [{\"text\": \"rigidity\", \"type\": \"Disease\"}, {\"text\": \"morphine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02030", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: There was a significant 40% improvement in the dyskinesia score without increase of parkinsonian motor disability.", "completion": "{\"entities\": [{\"text\": \"dyskinesia\", \"type\": \"Disease\"}, {\"text\": \"parkinsonian\", \"type\": \"Disease\"}, {\"text\": \"motor disability\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02807", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The duration of the examination and the mean ejection fraction (EF) were 16.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00799", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: STUDY DESIGN AND METHODS: Plasma samples from before and after CPB were analyzed postoperatively for argatroban concentration using a modified ecarin clotting time (ECT) assay.", "completion": "{\"entities\": [{\"text\": \"argatroban\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02707", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: She reported her use of methamphetamine for five years and had not experienced any major carious episodes before she started using the drug.", "completion": "{\"entities\": [{\"text\": \"methamphetamine\", \"type\": \"Chemical\"}, {\"text\": \"carious episodes\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04530", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We confirmed several cases of transformation from exencephaly to anencephaly.", "completion": "{\"entities\": [{\"text\": \"exencephaly\", \"type\": \"Disease\"}, {\"text\": \"anencephaly\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00241", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Changes in heart size during long - term timolol treatment after myocardial infarction.", "completion": "{\"entities\": [{\"text\": \"timolol\", \"type\": \"Chemical\"}, {\"text\": \"myocardial infarction\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04695", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A 34 - year - old lady developed a constellation of dermatitis, fever, lymphadenopathy and hepatitis, beginning on the 17th day of a course of oral sulphasalazine for sero - negative rheumatoid arthritis.", "completion": "{\"entities\": [{\"text\": \"dermatitis\", \"type\": \"Disease\"}, {\"text\": \"fever\", \"type\": \"Disease\"}, {\"text\": \"lymphadenopathy\", \"type\": \"Disease\"}, {\"text\": \"hepatitis\", \"type\": \"Disease\"}, {\"text\": \"sulphasalazine\", \"type\": \"Chemical\"}, {\"text\": \"rheumatoid arthritis\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-04181", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The role of nicotine in smoking - related cardiovascular disease.", "completion": "{\"entities\": [{\"text\": \"nicotine\", \"type\": \"Chemical\"}, {\"text\": \"cardiovascular disease\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01681", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The present study was aimed to investigate the combined effects of green tea and vitamin E on heart weight, body weight, serum marker enzymes, lipid peroxidation, endogenous antioxidants and membrane bound ATPases in isoproterenol (ISO )- induced myocardial infarction in rats.", "completion": "{\"entities\": [{\"text\": \"green tea\", \"type\": \"Chemical\"}, {\"text\": \"vitamin E\", \"type\": \"Chemical\"}, {\"text\": \"isoproterenol\", \"type\": \"Chemical\"}, {\"text\": \"ISO\", \"type\": \"Chemical\"}, {\"text\": \"myocardial infarction\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-01423", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 mg / kg BW) intoxication was studied in 9 - 10 - weeks - old Han - Wistar male rats.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04126", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Groups were compared for preoperative laboratory variables, diagnosis, postoperative variables, survival, type of ESRD therapy, and survival from onset of ESRD.", "completion": "{\"entities\": [{\"text\": \"ESRD\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00450", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Treatment was comprised of VNB, 25 mg / m (2 ), plus GEM, 1000 mg / m (2 ), both on Days 1, 8, and 15 every 28 days.", "completion": "{\"entities\": [{\"text\": \"VNB\", \"type\": \"Chemical\"}, {\"text\": \"GEM\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03467", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Bovine liver erythroid cells were cultured on monolayers of human bone marrow endothelial cells previously treated with EPO and IGF - IL - 3.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03423", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: changes are due to blockade of histamine H2 - receptors in the central nervous system.", "completion": "{\"entities\": [{\"text\": \"histamine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02954", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Atypical sensations following the use of subcutaneous sumatriptan are common, but of uncertain origin.", "completion": "{\"entities\": [{\"text\": \"Atypical sensations\", \"type\": \"Disease\"}, {\"text\": \"sumatriptan\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02642", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: By day 4, foot process effacement was complete and proteinuria appeared in parallel with signs of size barrier damage.", "completion": "{\"entities\": [{\"text\": \"proteinuria\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01580", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Progressive myopathy with up - regulation of MHC - I associated with statin therapy.", "completion": "{\"entities\": [{\"text\": \"myopathy\", \"type\": \"Disease\"}, {\"text\": \"statin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04747", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Routine EKG monitoring during infusional cyclophosphamide did not predict CHF", "completion": "{\"entities\": [{\"text\": \"cyclophosphamide\", \"type\": \"Chemical\"}, {\"text\": \"CHF\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04837", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The antiepileptic drugs, phenobarbitone and carbamazepine are well known to cause cognitive impairment on chronic use.", "completion": "{\"entities\": [{\"text\": \"phenobarbitone\", \"type\": \"Chemical\"}, {\"text\": \"carbamazepine\", \"type\": \"Chemical\"}, {\"text\": \"cognitive impairment\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00557", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: An objective causality assessment revealed that the adverse drug event was probably related to the use of ticlopidine.", "completion": "{\"entities\": [{\"text\": \"ticlopidine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00896", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The rabbit syndrome is an extrapyramidal side effect associated with chronic neuroleptic therapy.", "completion": "{\"entities\": [{\"text\": \"rabbit syndrome\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-reassigned-04245", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 3% below control; p < 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02174", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The following were measured: spontaneous pain, pain evoked by punctate and brush stimuli (VAS ), and areas of brush - evoked and punctate - evoked hyperalgesia.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"hyperalgesia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03625", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Brain natriuretic peptide is a predictor of anthracycline - induced cardiotoxicity.", "completion": "{\"entities\": [{\"text\": \"anthracycline\", \"type\": \"Chemical\"}, {\"text\": \"cardiotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00488", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Switches to hypomania or mania occurred in 27% of all patients (N = 12 )(and in 24% of the subgroup of patients treated with SSRIs [8 / 33 ]); 16 %(N = 7) experienced manic episodes, and 11 %(N = 5) experienced hypomanic episodes.", "completion": "{\"entities\": [{\"text\": \"hypomania\", \"type\": \"Disease\"}, {\"text\": \"mania\", \"type\": \"Disease\"}, {\"text\": \"SSRIs\", \"type\": \"Chemical\"}, {\"text\": \"manic\", \"type\": \"Disease\"}, {\"text\": \"hypomanic\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-04674", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 4% with rizatriptan and 15.", "completion": "{\"entities\": [{\"text\": \"rizatriptan\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05156", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Acute reserpine and subchronic haloperidol treatments change synaptosomal brain glutamate uptake and elicit orofacial dyskinesia in rats.", "completion": "{\"entities\": [{\"text\": \"reserpine\", \"type\": \"Chemical\"}, {\"text\": \"haloperidol\", \"type\": \"Chemical\"}, {\"text\": \"glutamate\", \"type\": \"Chemical\"}, {\"text\": \"orofacial dyskinesia\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04907", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: A 25 - year - old woman with Graves' disease had a febrile illness and evidence of pericarditis, which was confirmed by biopsy.", "completion": "{\"entities\": [{\"text\": \"Graves' disease\", \"type\": \"Disease\"}, {\"text\": \"febrile illness\", \"type\": \"Disease\"}, {\"text\": \"pericarditis\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01345", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thus, the relationship between cholinergic activity and responsiveness and alcohol withdrawal was investigated in a genetic animal model of ethanol withdrawal severity.", "completion": "{\"entities\": [{\"text\": \"alcohol\", \"type\": \"Chemical\"}, {\"text\": \"ethanol\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03148", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Other side effects were rare, and peripheral neurotoxicity has been minor (26% grade 1 ). CONCLUSION: These data indicate that VNB is an active agent in metastatic esophageal squamous cell carcinoma.", "completion": "{\"entities\": [{\"text\": \"peripheral neurotoxicity\", \"type\": \"Disease\"}, {\"text\": \"VNB\", \"type\": \"Chemical\"}, {\"text\": \"esophageal squamous cell carcinoma\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02219", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 3% of children and adolescents are affected by major depression.", "completion": "{\"entities\": [{\"text\": \"major depression\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04750", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Of 18 consecutive referrals of children with resistant typical absences only, eight were erroneously treated with carbamazepine either as monotherapy or as an add - on.", "completion": "{\"entities\": [{\"text\": \"carbamazepine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-reassigned-02807", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The abolition of muscle fasciculations (by 0.", "completion": "{\"entities\": [{\"text\": \"fasciculations\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02666", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We studied the role of xanthine oxidase (XO ), which is implicated in the production of reactive oxygen species, in dexamethasone - induced hypertension (dex - HT ). 3.", "completion": "{\"entities\": [{\"text\": \"xanthine\", \"type\": \"Chemical\"}, {\"text\": \"dex\", \"type\": \"Chemical\"}, {\"text\": \"dexamethasone\", \"type\": \"Chemical\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}, {\"text\": \"HT\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-01563", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In almost half of these women severe atherosclerosis of the aorta was present (n = 11 ), while in women without hormone use severe atherosclerosis of the aorta was present in less than 20 %(OR 3.", "completion": "{\"entities\": [{\"text\": \"atherosclerosis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00285", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Effect of aspirin on N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide - induced epithelial proliferation in the urinary bladder and forestomach of the rat.", "completion": "{\"entities\": [{\"text\": \"aspirin\", \"type\": \"Chemical\"}, {\"text\": \"N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05132", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The aim of this study was to investigate the effect of Rg1 on learning impairment by chronic morphine administration and the mechanism responsible for this effect.", "completion": "{\"entities\": [{\"text\": \"Rg1\", \"type\": \"Chemical\"}, {\"text\": \"learning impairment\", \"type\": \"Disease\"}, {\"text\": \"morphine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01613", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Neuroinflammation and behavioral abnormalities after neonatal terbutaline treatment in rats: implications for autism.", "completion": "{\"entities\": [{\"text\": \"Neuroinflammation\", \"type\": \"Disease\"}, {\"text\": \"behavioral abnormalities\", \"type\": \"Disease\"}, {\"text\": \"terbutaline\", \"type\": \"Chemical\"}, {\"text\": \"autism\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00517", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: e ., levonorgestrel) oral contraceptives, the dose of estrogen, and the presence or absence of prothrombotic mutations METHODS: In a nationwide, population - based, case - control study, we identified and enrolled 248 women 18 through 49 years of age who had had a first myocardial infarction between 1990 and 1995 and 925 control women who had not had a myocardial infarction and who were matched for age, calendar year of the index event, and area of residence.", "completion": "{\"entities\": [{\"text\": \"levonorgestrel\", \"type\": \"Chemical\"}, {\"text\": \"oral contraceptives\", \"type\": \"Chemical\"}, {\"text\": \"estrogen\", \"type\": \"Chemical\"}, {\"text\": \"myocardial infarction\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00697", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A higher residual serum concentration of temazepam", "completion": "{\"entities\": [{\"text\": \"temazepam\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01648", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In experiments using specific adrenergic antagonists, we found that pretreatment with the beta - adrenergic receptor antagonist propranolol blocked cocaine - induced anxiety - like behavior in Dbh +/- and wild - type C57BL6 / J mice, while the alpha (1) antagonist prazosin and the alpha (2) antagonist yohimbine had no effect.", "completion": "{\"entities\": [{\"text\": \"propranolol\", \"type\": \"Chemical\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"anxiety\", \"type\": \"Disease\"}, {\"text\": \"prazosin\", \"type\": \"Chemical\"}, {\"text\": \"yohimbine\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-00056", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The electrocardiograms (ECG) of 99 cocaine - abusing patients were compared with the ECGs of 50 schizophrenic controls.", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"schizophrenic\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04491", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Eight healthy men were recruited.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01829", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: v .). Baseline circumflex coronary blood flows did not differ significantly among treatment groups.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02699", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Clinicians should be aware of potential hepatotoxicity with simvastatin-ezetimibe", "completion": "{\"entities\": [{\"text\": \"hepatotoxicity\", \"type\": \"Disease\"}, {\"text\": \"simvastatin-ezetimibe\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04818", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: No side effect was noted during the course of therapy.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00869", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, 10 cm H2O CPAP decreased arterial blood pressure, cardiac output, and QS / QT.", "completion": "{\"entities\": [{\"text\": \"H2O\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04018", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Intracerebral hemorrhage is associated with more inflammation than ischemic stroke.", "completion": "{\"entities\": [{\"text\": \"Intracerebral hemorrhage\", \"type\": \"Disease\"}, {\"text\": \"inflammation\", \"type\": \"Disease\"}, {\"text\": \"ischemic stroke\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-reassigned-00219", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Linezolid - induced optic neuropathy.", "completion": "{\"entities\": [{\"text\": \"Linezolid\", \"type\": \"Chemical\"}, {\"text\": \"optic neuropathy\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01370", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: Cyproterone acetate combined with ethinyl estradiol (CPA / EE) is licensed in the UK for the treatment of women with acne and hirsutism and is also a treatment option for polycystic ovary syndrome (PCOS ). Previous studies have demonstrated an increased risk of venous thromboembolism (VTE) associated with CPA / EE compared with conventional combined oral contraceptives (COCs ). We believe the results of those studies may have been affected by residual confounding.", "completion": "{\"entities\": [{\"text\": \"Cyproterone acetate\", \"type\": \"Chemical\"}, {\"text\": \"ethinyl estradiol\", \"type\": \"Chemical\"}, {\"text\": \"CPA\", \"type\": \"Chemical\"}, {\"text\": \"EE\", \"type\": \"Chemical\"}, {\"text\": \"acne\", \"type\": \"Disease\"}, {\"text\": \"hirsutism\", \"type\": \"Disease\"}, {\"text\": \"polycystic ovary syndrome\", \"type\": \"Disease\"}, {\"text\": \"PCOS\", \"type\": \"Disease\"}, {\"text\": \"venous thromboembolism\", \"type\": \"Disease\"}, {\"text\": \"VTE\", \"type\": \"Disease\"}, {\"text\": \"oral contraceptives\", \"type\": \"Chemical\"}]}", "n_entities": 11}
{"ref": "bc5cdr-train-03589", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: Fibrin sealants (FS) derived from human plasma are frequently used in neurosurgery.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02598", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: PERSPECTIVE: Study findings indicate that the metabolism, neurocognitive effects, and physical side effects of oral oxycodone", "completion": "{\"entities\": [{\"text\": \"oxycodone\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00604", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: injections of U-II on behavioral, metabolic, and endocrine responses in mice.", "completion": "{\"entities\": [{\"text\": \"U-II\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02590", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In most patients, discontinuation of sirolimus resulted in a decrease, but not resolution, of proteinuria.", "completion": "{\"entities\": [{\"text\": \"sirolimus\", \"type\": \"Chemical\"}, {\"text\": \"proteinuria\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04658", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 3% of patients preferring rizatriptan and 54.", "completion": "{\"entities\": [{\"text\": \"rizatriptan\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04335", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: Thoracic aorta of male Sprague - Dawley rats was exposed to 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00840", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: IMPORTANCE OF THE FIELD: Fluoropyrimidines, in particular 5-fluorouracil (5-FU ), have been the mainstay of treatment for several solid tumors, including colorectal, breast and head and neck cancers, for > 40 years.", "completion": "{\"entities\": [{\"text\": \"Fluoropyrimidines\", \"type\": \"Chemical\"}, {\"text\": \"5-fluorouracil\", \"type\": \"Chemical\"}, {\"text\": \"5-FU\", \"type\": \"Chemical\"}, {\"text\": \"tumors\", \"type\": \"Disease\"}, {\"text\": \"colorectal, breast and head and neck cancers\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-02300", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: Delirium was found in 10% of clozapine - treated inpatients, particularly in older patients exposed to other central anticholinergics.", "completion": "{\"entities\": [{\"text\": \"Delirium\", \"type\": \"Disease\"}, {\"text\": \"clozapine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04412", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We have utilized the human monocyte cell line, THP - 1 as a model to address this question.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00868", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Five cm H2O CPAP during nitroprusside did not further alter any of the above - mentioned variables.", "completion": "{\"entities\": [{\"text\": \"H2O\", \"type\": \"Chemical\"}, {\"text\": \"nitroprusside\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03473", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: in control Krebs - Ringer containing 137 mM Na and 1.", "completion": "{\"entities\": [{\"text\": \"Na\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00295", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The magnitude and time course of the increase in heart rate and the decrease in systolic blood pressure after nitroglycerin were similar in the normal and diabetic subjects without autonomic neuropathy, whereas a lesser increase in heart rate and a greater decrease in systolic blood pressure occurred in the diabetic subjects with autonomic neuropathy.", "completion": "{\"entities\": [{\"text\": \"nitroglycerin\", \"type\": \"Chemical\"}, {\"text\": \"diabetic\", \"type\": \"Disease\"}, {\"text\": \"autonomic neuropathy\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02031", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Ballistic and choreic dyskinesia were markedly ameliorated, whereas dystonia was not.", "completion": "{\"entities\": [{\"text\": \"dyskinesia\", \"type\": \"Disease\"}, {\"text\": \"dystonia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01891", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A report of two cases.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02739", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 11 ml / min ). Groups 3 and 4 were studied at four and at six months to assess the effect of enalapril on progression of renal injury in adriamycin nephrosis.", "completion": "{\"entities\": [{\"text\": \"enalapril\", \"type\": \"Chemical\"}, {\"text\": \"renal injury\", \"type\": \"Disease\"}, {\"text\": \"adriamycin\", \"type\": \"Chemical\"}, {\"text\": \"nephrosis\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03918", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: WR-2721 or amifostine initially was developed to protect military personnel in the event of nuclear war.", "completion": "{\"entities\": [{\"text\": \"WR-2721\", \"type\": \"Chemical\"}, {\"text\": \"amifostine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01231", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Angioedema due to ACE inhibitors: common and inadequately diagnosed.", "completion": "{\"entities\": [{\"text\": \"Angioedema\", \"type\": \"Disease\"}, {\"text\": \"ACE inhibitors\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03099", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We conclude that the interpeduncular nucleus mediates nicotinic depression", "completion": "{\"entities\": [{\"text\": \"depression\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01668", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Patients had received a median of 2 (range, 1 - 4) prior regimens.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-reassigned-02331", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Hypertension in neuroblastoma induced by imipramine.", "completion": "{\"entities\": [{\"text\": \"Hypertension\", \"type\": \"Disease\"}, {\"text\": \"neuroblastoma\", \"type\": \"Disease\"}, {\"text\": \"imipramine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00841", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: AREAS COVERED IN THIS REVIEW: This article reviews the pharmacology and efficacy of capecitabine with a special emphasis on its safety.", "completion": "{\"entities\": [{\"text\": \"capecitabine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00079", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Her acetylcholine receptor antibody level was markedly elevated.", "completion": "{\"entities\": [{\"text\": \"acetylcholine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01364", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Six - to 9 - month old rats receiving prenatal dexamethasone on days 17 and 18 of gestation had a 17% reduction in glomeruli (23 380 +/- 587) compared with control rats (P < 0.", "completion": "{\"entities\": [{\"text\": \"dexamethasone\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02752", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Butyrylcholinesterase gene mutations in patients with prolonged apnea after succinylcholine for electroconvulsive therapy.", "completion": "{\"entities\": [{\"text\": \"apnea\", \"type\": \"Disease\"}, {\"text\": \"succinylcholine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02188", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Introduction of tacrolimus as an alternative immunosuppressive agent resulted in the recurrence of TMA and the subsequent loss of the renal allograft.", "completion": "{\"entities\": [{\"text\": \"tacrolimus\", \"type\": \"Chemical\"}, {\"text\": \"TMA\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00026", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, studies into the dose necessary to combating scopolamine", "completion": "{\"entities\": [{\"text\": \"scopolamine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03838", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Physicians who use sulfasalazine to treat patients with inflammatory bowel disease should be aware of the signs of sulfasalazine - induced lupus syndrome", "completion": "{\"entities\": [{\"text\": \"sulfasalazine\", \"type\": \"Chemical\"}, {\"text\": \"inflammatory bowel disease\", \"type\": \"Disease\"}, {\"text\": \"lupus syndrome\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01925", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Minimal cholestasis was seen in two cases and portal fibrosis of a reversible degree in eight.", "completion": "{\"entities\": [{\"text\": \"cholestasis\", \"type\": \"Disease\"}, {\"text\": \"fibrosis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04602", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Graded dobutamine infusions of 0.", "completion": "{\"entities\": [{\"text\": \"dobutamine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04608", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: End - systolic left ventricular posterior wall dimension at baseline for the doxorubicin - treated group was 11 +/- 1.", "completion": "{\"entities\": [{\"text\": \"doxorubicin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05055", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The effect of humoral modulators on the morphine - induced increase in locomotor activity of mice was studied.", "completion": "{\"entities\": [{\"text\": \"morphine\", \"type\": \"Chemical\"}, {\"text\": \"increase in locomotor activity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04192", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: She was admitted to the medical intensive care unit, venlafaxine was discontinued, and no further sequelae were seen.", "completion": "{\"entities\": [{\"text\": \"venlafaxine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01637", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: FINDINGS: A 28 - year - old man suffering from idiopathic epilepsy with generalized seizures was treated with LEV (3000 mg) added to valproate (VPA )(2000 mg ). Frequency of generalized tonic-clonic seizures increased from one per 6 months to two per month.", "completion": "{\"entities\": [{\"text\": \"idiopathic epilepsy\", \"type\": \"Disease\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}, {\"text\": \"LEV\", \"type\": \"Chemical\"}, {\"text\": \"valproate\", \"type\": \"Chemical\"}, {\"text\": \"VPA\", \"type\": \"Chemical\"}, {\"text\": \"tonic-clonic seizures\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-00781", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Confusion mostly occurred during the two first weeks following valproic acid exposure (39.", "completion": "{\"entities\": [{\"text\": \"Confusion\", \"type\": \"Disease\"}, {\"text\": \"valproic acid\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04040", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The characteristics of the 48 patients in the possible cases were similar.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01598", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: As a consequence of blocking I (f ), clonidine reduced the slope of the diastolic depolarization and the frequency of pacemaker potentials in sinoatrial node cells from wild - type and alpha2ABC - knockout mice.", "completion": "{\"entities\": [{\"text\": \"clonidine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01290", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: At doses where alone, they produced no significant effects on locomotion, BD1018, BD1063 and LR132 significantly attenuated the locomotor stimulatory effects of cocaine.", "completion": "{\"entities\": [{\"text\": \"BD1018\", \"type\": \"Chemical\"}, {\"text\": \"BD1063\", \"type\": \"Chemical\"}, {\"text\": \"LR132\", \"type\": \"Chemical\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04617", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The ventricular fibrillation threshold was measured by passing a gated train of 12 constant current pulses through the ventricular myocardium during the vulnerable period of the cardiac cycle.", "completion": "{\"entities\": [{\"text\": \"ventricular fibrillation\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03896", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: p .) per se had no effect on these parameters.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-05064", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: And the results are consistent with the hypothesis that morphine acts by retarding the release of acetylcholine at some central cholinergic synapses.", "completion": "{\"entities\": [{\"text\": \"morphine\", \"type\": \"Chemical\"}, {\"text\": \"acetylcholine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-04477", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 76) for pyrazolones, 0.", "completion": "{\"entities\": [{\"text\": \"pyrazolones\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02578", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Clinically significant proteinuria following the administration of sirolimus to renal transplant recipients.", "completion": "{\"entities\": [{\"text\": \"proteinuria\", \"type\": \"Disease\"}, {\"text\": \"sirolimus\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01028", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Despite reports to the contrary, it is suggested that sulphasalazine", "completion": "{\"entities\": [{\"text\": \"sulphasalazine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01928", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cross - sectional echocardiography was used to evaluate two neonates whose mothers ingested lithium during pregnancy.", "completion": "{\"entities\": [{\"text\": \"lithium\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-reassigned-02837", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Etomidate: a foreshortened clinical trial.", "completion": "{\"entities\": [{\"text\": \"Etomidate\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01347", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Animals were administered nicotine, carbachol, or neostigmine via timed tail vein infusion, and the latencies to onset of tremor and clonus were recorded and converted to threshold dose.", "completion": "{\"entities\": [{\"text\": \"nicotine\", \"type\": \"Chemical\"}, {\"text\": \"carbachol\", \"type\": \"Chemical\"}, {\"text\": \"neostigmine\", \"type\": \"Chemical\"}, {\"text\": \"tremor\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04279", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This report describes the first published case of cardiorespiratory arrest and death associated with intramuscular administration of midazolam.", "completion": "{\"entities\": [{\"text\": \"cardiorespiratory arrest\", \"type\": \"Disease\"}, {\"text\": \"death\", \"type\": \"Disease\"}, {\"text\": \"midazolam\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02593", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Comparative cognitive and subjective side effects of immediate - release oxycodone in healthy middle - aged and older adults.", "completion": "{\"entities\": [{\"text\": \"oxycodone\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00835", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This study analyzed the incidence of neurological complications during ALL treatment in a single pediatric institution, focusing on clinical, radiological, and electrophysiological findings.", "completion": "{\"entities\": [{\"text\": \"neurological complications\", \"type\": \"Disease\"}, {\"text\": \"ALL\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01602", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The influence of smoking during pregnancy on the developing cochlea has not been estimated, although smoking has been positively associated with hearing loss in adults.", "completion": "{\"entities\": [{\"text\": \"smoking\", \"type\": \"Chemical\"}, {\"text\": \"hearing loss\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01322", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The intensity of headache and nausea was measured with a 100 - mm visual analog scale.", "completion": "{\"entities\": [{\"text\": \"headache\", \"type\": \"Disease\"}, {\"text\": \"nausea\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01865", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The cataleptogenic effect of THC was significantly reduced in rats treated with 6-OHDA and in rats with lesions of the locus coeruleus but not in rats treated with desipramine and 6-OHDA, as compared with control rats.", "completion": "{\"entities\": [{\"text\": \"THC\", \"type\": \"Chemical\"}, {\"text\": \"6-OHDA\", \"type\": \"Chemical\"}, {\"text\": \"desipramine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01306", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: For compounds that have shown TDP in the clinic (terfenadine, terodiline, cisapride) there is little differentiation between the dog ED50 and the efficacious free plasma concentrations in man (< 10 - fold) reflecting their limited safety margins.", "completion": "{\"entities\": [{\"text\": \"TDP\", \"type\": \"Disease\"}, {\"text\": \"terfenadine\", \"type\": \"Chemical\"}, {\"text\": \"terodiline\", \"type\": \"Chemical\"}, {\"text\": \"cisapride\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04555", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In both cases, discontinuation of FK506 and treatment with plasma exchange, fresh frozen plasma replacement, corticosteroids, aspirin, and dipyridamole led to resolution of MAHA.", "completion": "{\"entities\": [{\"text\": \"FK506\", \"type\": \"Chemical\"}, {\"text\": \"corticosteroids\", \"type\": \"Chemical\"}, {\"text\": \"aspirin\", \"type\": \"Chemical\"}, {\"text\": \"dipyridamole\", \"type\": \"Chemical\"}, {\"text\": \"MAHA\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-03579", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Of the remainder, a relationship to clioquinol was considered probable in 42 and possible in 69 cases.", "completion": "{\"entities\": [{\"text\": \"clioquinol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02028", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Improvement of levodopa - induced dyskinesia by propranolol in Parkinson's disease.", "completion": "{\"entities\": [{\"text\": \"levodopa\", \"type\": \"Chemical\"}, {\"text\": \"dyskinesia\", \"type\": \"Disease\"}, {\"text\": \"propranolol\", \"type\": \"Chemical\"}, {\"text\": \"Parkinson's disease\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00590", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Coronary aneurysm after implantation of a paclitaxel - eluting stent.", "completion": "{\"entities\": [{\"text\": \"Coronary aneurysm\", \"type\": \"Disease\"}, {\"text\": \"paclitaxel\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04223", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Severe cardiovascular complications occurred in eight of 160 patients treated with terbutaline for preterm labor", "completion": "{\"entities\": [{\"text\": \"cardiovascular complications\", \"type\": \"Disease\"}, {\"text\": \"terbutaline\", \"type\": \"Chemical\"}, {\"text\": \"preterm labor\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01567", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: No association was found for hormone use less than 1 year.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03420", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The cerebrospinal fluid: serum ratio of cimetidine concentrations was 0.", "completion": "{\"entities\": [{\"text\": \"cimetidine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02876", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Following rTMS, no side effects and no adverse effects on motor function and PD symptoms were noted.", "completion": "{\"entities\": [{\"text\": \"PD\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04741", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: STUDY DESIGN: We combined paclitaxel, melphalan and high - dose cyclophosphamide, thiotepa, and carboplatin in a triple sequential high - dose regimen for patients with metastatic breast cancer.", "completion": "{\"entities\": [{\"text\": \"paclitaxel\", \"type\": \"Chemical\"}, {\"text\": \"melphalan\", \"type\": \"Chemical\"}, {\"text\": \"cyclophosphamide\", \"type\": \"Chemical\"}, {\"text\": \"thiotepa\", \"type\": \"Chemical\"}, {\"text\": \"carboplatin\", \"type\": \"Chemical\"}, {\"text\": \"breast cancer\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-02297", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 4% of cases were moderate or severe.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04719", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The dosage of indocyanine green used for angiography varied from 25 to 75 mg, depending upon the institution.", "completion": "{\"entities\": [{\"text\": \"indocyanine green\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02117", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These findings suggest some validity for the new DSM - IV diagnosis of CIMD", "completion": "{\"entities\": [{\"text\": \"CIMD\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04089", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: With widespread use of antimicrobial agents, however, hepatic injury occurs frequently, and among adverse drug reactions, idiosyncratic reactions are the most serious.", "completion": "{\"entities\": [{\"text\": \"hepatic injury\", \"type\": \"Disease\"}, {\"text\": \"adverse drug reactions\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01186", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The MFL regimen achieves little palliative benefit and induces severe toxicity at a fairly high rate.", "completion": "{\"entities\": [{\"text\": \"MFL regimen\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03421", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 24: 1 and indicates that cimetidine passes the blood - brain barrier; it also raises the possibility that M.", "completion": "{\"entities\": [{\"text\": \"cimetidine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03046", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In four patients, polymorphous ventricular tachycardia appeared after intravenous administration of 200 to 400 mg of procainamide for the treatment of sustained ventricular tachycardia.", "completion": "{\"entities\": [{\"text\": \"ventricular tachycardia\", \"type\": \"Disease\"}, {\"text\": \"procainamide\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00948", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After detailing the course of events, we discuss the role of paradoxical coronary spasm and hypotension - mediated myocardial ischemia occurring downstream to significant coronary arterial stenosis in the pathophysiology of acute coronary insufficiency", "completion": "{\"entities\": [{\"text\": \"spasm\", \"type\": \"Disease\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}, {\"text\": \"myocardial ischemia\", \"type\": \"Disease\"}, {\"text\": \"coronary arterial stenosis\", \"type\": \"Disease\"}, {\"text\": \"acute coronary insufficiency\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-02259", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Amount of bleeding and hematoma size in the collagenase - induced intracerebral hemorrhage rat model.", "completion": "{\"entities\": [{\"text\": \"bleeding\", \"type\": \"Disease\"}, {\"text\": \"hematoma\", \"type\": \"Disease\"}, {\"text\": \"intracerebral hemorrhage\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03822", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Clinical experience with lovastatin includes over 5000 patients, 700 of whom have been treated for 2 years or more, and experience with simvastatin includes over 3500 patients, of whom 350 have been treated for 18 months or more.", "completion": "{\"entities\": [{\"text\": \"lovastatin\", \"type\": \"Chemical\"}, {\"text\": \"simvastatin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03612", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Nine days later locomotor activity was measured in response to a single low dose of amphetamine (0.", "completion": "{\"entities\": [{\"text\": \"amphetamine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02678", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Allopurinol did not prevent dex - HT.", "completion": "{\"entities\": [{\"text\": \"Allopurinol\", \"type\": \"Chemical\"}, {\"text\": \"dex\", \"type\": \"Chemical\"}, {\"text\": \"HT\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04935", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, the occurrence of central adverse effects should be taken into account, especially when using higher doses.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02994", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Both anti - arrhythmic efficacy and bioavailability were compared to oral drug.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03894", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05 ). However, pretreatment with RAMH significantly reversed such an effect of THP (15 mg / kg i.", "completion": "{\"entities\": [{\"text\": \"RAMH\", \"type\": \"Chemical\"}, {\"text\": \"THP\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04299", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 4 mumol) of either cocaine or BE were injected ventricularly in unanesthetized juvenile rats.", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"BE\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00861", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This was accounted for by a significant number of depressions occurring in methyl dopa treated patients with psychiatric", "completion": "{\"entities\": [{\"text\": \"depressions\", \"type\": \"Disease\"}, {\"text\": \"methyl dopa\", \"type\": \"Chemical\"}, {\"text\": \"psychiatric\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03231", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Although the sP120T substitution also impaired HBsAg secretion, it did not enhance the replication of LAM - resistant clones.", "completion": "{\"entities\": [{\"text\": \"HBsAg\", \"type\": \"Chemical\"}, {\"text\": \"LAM\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01920", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Its prolonged use or overuse has been associated with seizures, intracerebral hemorrhage, neuropsychiatric symptoms, and nonhemorrhagic cerebral infarction.", "completion": "{\"entities\": [{\"text\": \"seizures\", \"type\": \"Disease\"}, {\"text\": \"intracerebral hemorrhage\", \"type\": \"Disease\"}, {\"text\": \"neuropsychiatric symptoms\", \"type\": \"Disease\"}, {\"text\": \"cerebral infarction\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04553", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Microangiopathic hemolytic anemia complicating FK506 (tacrolimus) therapy.", "completion": "{\"entities\": [{\"text\": \"Microangiopathic hemolytic anemia\", \"type\": \"Disease\"}, {\"text\": \"FK506\", \"type\": \"Chemical\"}, {\"text\": \"tacrolimus\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01929", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In one infant, Ebstein's anomaly of the tricuspid valve was identified.", "completion": "{\"entities\": [{\"text\": \"Ebstein's anomaly\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04222", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cardiovascular complications associated with terbutaline treatment for preterm labor.", "completion": "{\"entities\": [{\"text\": \"Cardiovascular complications\", \"type\": \"Disease\"}, {\"text\": \"terbutaline\", \"type\": \"Chemical\"}, {\"text\": \"preterm labor\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02504", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It is characterized by encephalopathy, headaches, seizures, or neurological deficits.", "completion": "{\"entities\": [{\"text\": \"encephalopathy\", \"type\": \"Disease\"}, {\"text\": \"headaches\", \"type\": \"Disease\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}, {\"text\": \"neurological deficits\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03692", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A phase I / II study of paclitaxel plus cisplatin as first - line therapy for head and neck cancers: preliminary results.", "completion": "{\"entities\": [{\"text\": \"paclitaxel\", \"type\": \"Chemical\"}, {\"text\": \"cisplatin\", \"type\": \"Chemical\"}, {\"text\": \"head and neck cancers\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02562", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Doxorubicin - induced nephropathy leads to epithelial sodium channel (ENaC )- dependent volume retention and renal fibrosis.", "completion": "{\"entities\": [{\"text\": \"Doxorubicin\", \"type\": \"Chemical\"}, {\"text\": \"nephropathy\", \"type\": \"Disease\"}, {\"text\": \"sodium\", \"type\": \"Chemical\"}, {\"text\": \"volume retention\", \"type\": \"Disease\"}, {\"text\": \"fibrosis\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-04687", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Diagnosis of this potentially fatal complication may be delayed or missed if renal tissue or the peripheral blood smear is not examined, because renal failure may be ascribed to cisplatin nephrotoxicity and the anemia and thrombocytopenia to drug - induced bone marrow suppression", "completion": "{\"entities\": [{\"text\": \"renal failure\", \"type\": \"Disease\"}, {\"text\": \"cisplatin\", \"type\": \"Chemical\"}, {\"text\": \"nephrotoxicity\", \"type\": \"Disease\"}, {\"text\": \"anemia\", \"type\": \"Disease\"}, {\"text\": \"thrombocytopenia\", \"type\": \"Disease\"}, {\"text\": \"bone marrow suppression\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-02566", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Plasma aldosterone levels increased in nephrotic mice of both genotypes and was followed by increased SGK1 protein expression in sgk1 (+/+) mice.", "completion": "{\"entities\": [{\"text\": \"aldosterone\", \"type\": \"Chemical\"}, {\"text\": \"nephrotic\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01866", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: On the contrary, the cataleptogenic effect of haloperidol was significantly reduced in rats treated with desipramine and 6-OHDA but not in rats treated with 6-OHDA or in rats with lesions of the locus coeruleus.", "completion": "{\"entities\": [{\"text\": \"haloperidol\", \"type\": \"Chemical\"}, {\"text\": \"desipramine\", \"type\": \"Chemical\"}, {\"text\": \"6-OHDA\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04016", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Effect of fucoidan treatment on collagenase - induced intracerebral hemorrhage in rats.", "completion": "{\"entities\": [{\"text\": \"fucoidan\", \"type\": \"Chemical\"}, {\"text\": \"intracerebral hemorrhage\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03591", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Recently, synthetic fibrinolysis inhibitors such as tranexamic acid (tAMCA) have been considered as substitutes for aprotinin.", "completion": "{\"entities\": [{\"text\": \"tranexamic acid\", \"type\": \"Chemical\"}, {\"text\": \"tAMCA\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02539", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Topical papaverine was used as a direct therapeutic action to manage vasospasm in a total of 11 patients.", "completion": "{\"entities\": [{\"text\": \"papaverine\", \"type\": \"Chemical\"}, {\"text\": \"vasospasm\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03679", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cyclophosphamide therapy increases the risk of carcinoma of the bladder.", "completion": "{\"entities\": [{\"text\": \"Cyclophosphamide\", \"type\": \"Chemical\"}, {\"text\": \"carcinoma of the bladder\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00090", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Early onset migraine attacks were induced by nitroglycerin in seven out of 10 patients versus no patient in the placebo group.", "completion": "{\"entities\": [{\"text\": \"migraine\", \"type\": \"Disease\"}, {\"text\": \"nitroglycerin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04990", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: glycopyrrolate and atropine in the prevention of bradycardia and arrhythmias following repeated doses of suxamethonium in children.", "completion": "{\"entities\": [{\"text\": \"glycopyrrolate\", \"type\": \"Chemical\"}, {\"text\": \"atropine\", \"type\": \"Chemical\"}, {\"text\": \"bradycardia\", \"type\": \"Disease\"}, {\"text\": \"arrhythmias\", \"type\": \"Disease\"}, {\"text\": \"suxamethonium\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-00460", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 047 ). CONCLUSIONS: The combination of GEM and VNB is moderately active and well tolerated except in patients age >/= 75 years.", "completion": "{\"entities\": [{\"text\": \"GEM\", \"type\": \"Chemical\"}, {\"text\": \"VNB\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04592", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The basal tone of the right coronary artery was significantly lower than that of the left coronary artery.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00129", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Inhibition of sympathoadrenal activity by atrial natriuretic factor in dogs.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00091", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Subsequently 20 migraine patients, who developed an early onset attack with frontotemporal nitroglycerin, received the drug in a second induction test at other body areas.", "completion": "{\"entities\": [{\"text\": \"migraine\", \"type\": \"Disease\"}, {\"text\": \"nitroglycerin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05078", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Suxamethonium causes prolonged apnea in patients in whom pseudocholinesterase enzyme gets deactivated by organophosphorus (OP) poisons.", "completion": "{\"entities\": [{\"text\": \"Suxamethonium\", \"type\": \"Chemical\"}, {\"text\": \"apnea\", \"type\": \"Disease\"}, {\"text\": \"organophosphorus (OP) poisons\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01455", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: TCR protected against pathological changes induced by isoproterenol in rat heart.", "completion": "{\"entities\": [{\"text\": \"TCR\", \"type\": \"Chemical\"}, {\"text\": \"isoproterenol\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01059", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: Retrospective review of medical records of 236 patients with hyperthyroidism admitted in our department (in - or out - patients) from 1986 to 1992.", "completion": "{\"entities\": [{\"text\": \"hyperthyroidism\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02004", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The appearance of nephrotic syndromes such as proteinuria, hypoalbuminemia, hypercholesterolemia and increase in blood nitrogen urea, induced in rats by injection of puromycin aminonucleoside was markedly inhibited by oral administration of Dup 753 (losartan ), a novel angiotensin II receptor antagonist, at a dose of 1 or 2 mg / kg per day.", "completion": "{\"entities\": [{\"text\": \"nephrotic syndromes\", \"type\": \"Disease\"}, {\"text\": \"proteinuria\", \"type\": \"Disease\"}, {\"text\": \"hypoalbuminemia\", \"type\": \"Disease\"}, {\"text\": \"hypercholesterolemia\", \"type\": \"Disease\"}, {\"text\": \"blood nitrogen urea\", \"type\": \"Chemical\"}, {\"text\": \"puromycin aminonucleoside\", \"type\": \"Chemical\"}, {\"text\": \"Dup 753\", \"type\": \"Chemical\"}, {\"text\": \"losartan\", \"type\": \"Chemical\"}, {\"text\": \"angiotensin II\", \"type\": \"Chemical\"}]}", "n_entities": 9}
{"ref": "bc5cdr-train-03816", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Jaundice disappeared within 3 months but was followed by prolonged anicteric cholestasis marked by pruritus and high levels of alkaline phosphatase and gammaglutamyltransferase activities.", "completion": "{\"entities\": [{\"text\": \"Jaundice\", \"type\": \"Disease\"}, {\"text\": \"cholestasis\", \"type\": \"Disease\"}, {\"text\": \"pruritus\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-reassigned-04430", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: DESIGN: A retrospective observational cohort study.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00481", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Antidepressant - induced mania in bipolar patients: identification of risk factors.", "completion": "{\"entities\": [{\"text\": \"Antidepressant\", \"type\": \"Chemical\"}, {\"text\": \"mania\", \"type\": \"Disease\"}, {\"text\": \"bipolar\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02909", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Acetazolamide - induced nephrolithiasis: implications for treatment of neuromuscular disorders.", "completion": "{\"entities\": [{\"text\": \"Acetazolamide\", \"type\": \"Chemical\"}, {\"text\": \"nephrolithiasis\", \"type\": \"Disease\"}, {\"text\": \"neuromuscular disorders\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03737", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: MPA, BCC, DMCM, and STR showed no inhibition of 3H-TBOB (t-butyl bicyclo-orthobenzoate) binding at concentrations of 100 micron.", "completion": "{\"entities\": [{\"text\": \"MPA\", \"type\": \"Chemical\"}, {\"text\": \"BCC\", \"type\": \"Chemical\"}, {\"text\": \"DMCM\", \"type\": \"Chemical\"}, {\"text\": \"STR\", \"type\": \"Chemical\"}, {\"text\": \"3H-TBOB\", \"type\": \"Chemical\"}, {\"text\": \"t-butyl bicyclo-orthobenzoate\", \"type\": \"Chemical\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-00900", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The bronchodilator effects of a single dose of ipratropium bromide aerosol (36 micrograms) and short - acting theophylline tablets (dose titrated to produce serum levels of 10 - 20 micrograms / mL) were compared in a double - blind, placebo - controlled crossover study in 21 patients with stable, chronic obstructive pulmonary disease.", "completion": "{\"entities\": [{\"text\": \"ipratropium bromide\", \"type\": \"Chemical\"}, {\"text\": \"theophylline\", \"type\": \"Chemical\"}, {\"text\": \"chronic obstructive pulmonary disease\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04203", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The administration of intermittent intravenous infusions of cimetidine is infrequently associated with the development of bradyarrhythmias.", "completion": "{\"entities\": [{\"text\": \"cimetidine\", \"type\": \"Chemical\"}, {\"text\": \"bradyarrhythmias\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02722", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We concluded a critical time window for systemic lipopolysaccharide pretreatment in exerting effective protection against methamphetamine - induced nigrostriatal dopamine neurotoxicity", "completion": "{\"entities\": [{\"text\": \"lipopolysaccharide\", \"type\": \"Chemical\"}, {\"text\": \"methamphetamine\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}, {\"text\": \"neurotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00762", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Atherosclerosis could produce gastric hemorrhagic ulcer via aggravation of gastric acid back - diffusion, LPO generation, histamine release and microvascular permeability that could be ameliorated by verapamil", "completion": "{\"entities\": [{\"text\": \"Atherosclerosis\", \"type\": \"Disease\"}, {\"text\": \"gastric hemorrhagic\", \"type\": \"Disease\"}, {\"text\": \"ulcer\", \"type\": \"Disease\"}, {\"text\": \"histamine\", \"type\": \"Chemical\"}, {\"text\": \"verapamil\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-03998", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Allopregnanolone and pregnanolone, but not ganaxolone, also reduced cumulative lethality associated with kindling.", "completion": "{\"entities\": [{\"text\": \"Allopregnanolone\", \"type\": \"Chemical\"}, {\"text\": \"pregnanolone\", \"type\": \"Chemical\"}, {\"text\": \"ganaxolone\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01324", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: One study participant was excluded after protocol violation.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01076", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Acute confusion induced by a high - dose infusion of 5-fluorouracil and folinic acid.", "completion": "{\"entities\": [{\"text\": \"confusion\", \"type\": \"Disease\"}, {\"text\": \"5-fluorouracil\", \"type\": \"Chemical\"}, {\"text\": \"folinic acid\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00954", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The authors suggest that fluoxetine - induced akathisia may be caused by serotonergically mediated inhibition of dopaminergic neurotransmission and that the pathophysiology of fluoxetine - induced akathisia and tricyclic antidepressant", "completion": "{\"entities\": [{\"text\": \"fluoxetine\", \"type\": \"Chemical\"}, {\"text\": \"akathisia\", \"type\": \"Disease\"}, {\"text\": \"antidepressant\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03230", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The sG145R mutation strongly reduced HBsAg levels and was able to fully restore the impaired replication of LAM - resistant HBV mutants to the levels of wild - type HBV, and PC or BCP mutations further enhanced viral replication.", "completion": "{\"entities\": [{\"text\": \"HBsAg\", \"type\": \"Chemical\"}, {\"text\": \"LAM\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01968", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: There was only one case of dementia possibly due to cimetidine (with a drug level of 1.", "completion": "{\"entities\": [{\"text\": \"dementia\", \"type\": \"Disease\"}, {\"text\": \"cimetidine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-02726", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Each course was repeated monthly.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02434", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Physicians should be aware of this potential interaction and use caution when prescribing levofloxacin to patients taking warfarin", "completion": "{\"entities\": [{\"text\": \"levofloxacin\", \"type\": \"Chemical\"}, {\"text\": \"warfarin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05178", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Zonisamide is a broad - spectrum antiepileptic drug used to treat various types of seizures.", "completion": "{\"entities\": [{\"text\": \"Zonisamide\", \"type\": \"Chemical\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03959", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Atrial fibrillation in young patients without structural heart disease is rare.", "completion": "{\"entities\": [{\"text\": \"Atrial fibrillation\", \"type\": \"Disease\"}, {\"text\": \"heart disease\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01562", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Intramuscular hormone therapy use for 1 year or longer was reported by 25 women.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03608", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The present study examined whether female rats on various regimens of sugar access would show behavioral cross-sensitization to a low dose of amphetamine.", "completion": "{\"entities\": [{\"text\": \"behavioral cross-sensitization\", \"type\": \"Disease\"}, {\"text\": \"amphetamine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02878", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Disulfiram - like syndrome after hydrogen cyanamide professional skin exposure: two case reports in France.", "completion": "{\"entities\": [{\"text\": \"Disulfiram\", \"type\": \"Chemical\"}, {\"text\": \"hydrogen cyanamide\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01436", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Differential modulation by estrogen of alpha2 - adrenergic and I1 - imidazoline receptor - mediated hypotension in female rats.", "completion": "{\"entities\": [{\"text\": \"estrogen\", \"type\": \"Chemical\"}, {\"text\": \"imidazoline\", \"type\": \"Chemical\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04015", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05 ). CONCLUSION: This rat study demonstrated a synergistic nephrotoxic effect of CsA plus SRL, whereas FK506 plus SRL", "completion": "{\"entities\": [{\"text\": \"nephrotoxic\", \"type\": \"Disease\"}, {\"text\": \"CsA\", \"type\": \"Chemical\"}, {\"text\": \"SRL\", \"type\": \"Chemical\"}, {\"text\": \"FK506\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03751", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Finally, 6 weeks later, diffuse chorioretinal atrophy with optic atrophy occurred and the vision in his left eye was lost.", "completion": "{\"entities\": [{\"text\": \"chorioretinal atrophy\", \"type\": \"Disease\"}, {\"text\": \"optic atrophy\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-01578", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 4 microgram / kg / min.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02796", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: TEE is a semi - invasive tool broadly used and its utilization associated to sedatives drugs might to affect the procedure safety.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04876", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 7% gum ), as well as during the entire study (safety population: 63.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04746", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: As a result of these findings, oncologists should carefully monitor fluid balance in older patients.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04777", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thirteen patients developed a raised serum amylase without abdominal pain.", "completion": "{\"entities\": [{\"text\": \"abdominal pain\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02956", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Two patients are presented with tingling or burning sensations limited to areas of heat exposure or sunburn", "completion": "{\"entities\": [{\"text\": \"tingling or burning sensations\", \"type\": \"Disease\"}, {\"text\": \"sunburn\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04265", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These findings suggest that lowered serum prolactin levels in the early phase of bromocriptine treatment may result from an impaired secretion of prolactin due to decreasing numbers of cytoplasmic microtubules.", "completion": "{\"entities\": [{\"text\": \"bromocriptine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01096", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Positive MIF test for ampicillin showed sensitization of the patient' s lymphocytes to ampicillin.", "completion": "{\"entities\": [{\"text\": \"ampicillin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02384", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A chi - square test was used to assess the statistical significance of results.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02965", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In another series of measurements, reproducibility and reference values of the tremor was assessed in 65 healthy subjects in three sessions, at 9 a.", "completion": "{\"entities\": [{\"text\": \"tremor\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02778", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Minor side effects included nausea (thirteen patients ), emesis (eight of the thirteen patients with nausea ), clumsiness (evident as ataxic movements in ten patients ), and dysphoric reaction (one patient ). No long - term sequelae were noted, and no patients had hallucinations or nightmares.", "completion": "{\"entities\": [{\"text\": \"nausea\", \"type\": \"Disease\"}, {\"text\": \"emesis\", \"type\": \"Disease\"}, {\"text\": \"clumsiness\", \"type\": \"Disease\"}, {\"text\": \"ataxic movements\", \"type\": \"Disease\"}, {\"text\": \"dysphoric reaction\", \"type\": \"Disease\"}, {\"text\": \"hallucinations\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-03529", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Quantitative morphometric studies of the cerebellum provide valuable insights into the pathogenesis of cerebellar disorders", "completion": "{\"entities\": [{\"text\": \"cerebellar disorders\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02331", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We examined the role of the beta4 subunits in nicotine - induced seizures and hypolocomotion in beta4 homozygous null (beta4 -/-) and alpha3 heterozygous (+/-) mice.", "completion": "{\"entities\": [{\"text\": \"nicotine\", \"type\": \"Chemical\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}, {\"text\": \"hypolocomotion\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02149", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This study was conducted to examine whether prolonged pretreatment with isoproterenol could abolish bromocriptine - induced tachycardia in conscious rats.", "completion": "{\"entities\": [{\"text\": \"isoproterenol\", \"type\": \"Chemical\"}, {\"text\": \"bromocriptine\", \"type\": \"Chemical\"}, {\"text\": \"tachycardia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04209", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Because knowledge of stone composition is essential for studies of their pathogenesis, treatment, and prevention, this was investigated by direct and indirect methods in 14 octreotide treated acromegalic patients with gall stones.", "completion": "{\"entities\": [{\"text\": \"octreotide\", \"type\": \"Chemical\"}, {\"text\": \"acromegalic\", \"type\": \"Disease\"}, {\"text\": \"gall stones\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02828", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Recently, we found that therapy with selegiline and L-dopa was associated with selective systolic orthostatic hypotension which was abolished by withdrawal of selegiline.", "completion": "{\"entities\": [{\"text\": \"selegiline\", \"type\": \"Chemical\"}, {\"text\": \"L-dopa\", \"type\": \"Chemical\"}, {\"text\": \"systolic orthostatic hypotension\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04138", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Patients developing ESRD had a 6 - year survival after onset of ESRD of 27% for the patients receiving hemodialysis versus 71.", "completion": "{\"entities\": [{\"text\": \"ESRD\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04448", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Investigation of mitochondrial involvement in the experimental model of epilepsy induced by pilocarpine.", "completion": "{\"entities\": [{\"text\": \"epilepsy\", \"type\": \"Disease\"}, {\"text\": \"pilocarpine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01226", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The maximal NGF contents obtained by PG-9 were 17.", "completion": "{\"entities\": [{\"text\": \"PG-9\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05089", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 2 ), than in the placebo group, at 3.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00711", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Higher optical density of an antigen assay predicts thrombosis in patients with heparin - induced thrombocytopenia.", "completion": "{\"entities\": [{\"text\": \"thrombosis\", \"type\": \"Disease\"}, {\"text\": \"heparin\", \"type\": \"Chemical\"}, {\"text\": \"thrombocytopenia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02211", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Interestingly, all the drugs, such as, AAP, AMI and DOX induced apoptotic death in addition to necrosis in the respective organs which was very effectively blocked by GSPE.", "completion": "{\"entities\": [{\"text\": \"AAP\", \"type\": \"Chemical\"}, {\"text\": \"AMI\", \"type\": \"Chemical\"}, {\"text\": \"DOX\", \"type\": \"Chemical\"}, {\"text\": \"necrosis\", \"type\": \"Disease\"}, {\"text\": \"GSPE\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-04070", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The present study was designed to evaluate the cardioprotective potential of salvianolic acid A on isoproterenol - induced myocardial infarction in rats.", "completion": "{\"entities\": [{\"text\": \"salvianolic acid A\", \"type\": \"Chemical\"}, {\"text\": \"isoproterenol\", \"type\": \"Chemical\"}, {\"text\": \"myocardial infarction\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04294", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The half - life (t1 / 2) of cocaine is relatively short, but some of the consequences of its use, such as seizures and strokes, can occur hours after exposure.", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}, {\"text\": \"strokes\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03404", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Perinatal risk factors of infants with hearing loss were compared with those of two control groups matched for gestation and birth weight and for perinatal complications.", "completion": "{\"entities\": [{\"text\": \"hearing loss\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03869", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, combinations of different therapeutic regimens require consideration of potential adverse reactions.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00032", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: When comparing all lithium treated versus non - lithium - treated groups, lithium caused a reduction in glomerular filtration rate (GFR) without significant changes in effective renal plasma flow (as determined by a marker secreted into the proximal tubules) or lithium clearance.", "completion": "{\"entities\": [{\"text\": \"lithium\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01488", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In this study, we prospectively evaluated the incidence and clinical importance of pseudolithiasis in paediatric surgical patients receiving ceftriaxone treatment, who often had to fast in the post - operative period.", "completion": "{\"entities\": [{\"text\": \"pseudolithiasis\", \"type\": \"Disease\"}, {\"text\": \"ceftriaxone\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02026", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In 8 of the remaining 10 patients who developed gallstones during treatment, gallbladder contractility normalized in 5 patients (3 of whom has disappearance of their stones within 3 weeks ), and remained depressed in 3 (2 of whom had stones present at 6 months ). Our results suggest that the suppression of gallbladder contractility is the cause of the successive formation of bile sludge, gallstones, and cholecystitis during octreotide therapy in Chinese acromegalic patients.", "completion": "{\"entities\": [{\"text\": \"gallstones\", \"type\": \"Disease\"}, {\"text\": \"depressed\", \"type\": \"Disease\"}, {\"text\": \"cholecystitis\", \"type\": \"Disease\"}, {\"text\": \"octreotide\", \"type\": \"Chemical\"}, {\"text\": \"acromegalic\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-05006", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the absence of caffeine, acetaminophen (up to 300 mg / kg) did not modify the seizures induced by maximal electroshock and did not alter the convulsant dose of pentylenetetrezol in mice (tests performed by the Anticonvulsant Screening Project of NINCDS ). Acetaminophen (up to 150 micrograms / mL) did not retard the incorporation of radioactive adenosine into ATP in slices of rat cerebral cortex.", "completion": "{\"entities\": [{\"text\": \"caffeine\", \"type\": \"Chemical\"}, {\"text\": \"acetaminophen\", \"type\": \"Chemical\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}, {\"text\": \"pentylenetetrezol\", \"type\": \"Chemical\"}, {\"text\": \"Acetaminophen\", \"type\": \"Chemical\"}, {\"text\": \"adenosine\", \"type\": \"Chemical\"}, {\"text\": \"ATP\", \"type\": \"Chemical\"}]}", "n_entities": 7}
{"ref": "bc5cdr-train-03363", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Relative to desipramine alone, mean AUC and C (max) of desipramine increased 3.", "completion": "{\"entities\": [{\"text\": \"desipramine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02347", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Nitro-L-arginine methyl ester: a potential protector against gentamicin ototoxicity.", "completion": "{\"entities\": [{\"text\": \"Nitro-L-arginine methyl ester\", \"type\": \"Chemical\"}, {\"text\": \"gentamicin\", \"type\": \"Chemical\"}, {\"text\": \"ototoxicity\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01595", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 6 %(100 microg / kg) of the effect in wild - type mice.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02797", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: OBJECTIVE: to analyze aspects of TEE safety associated to the use of Midazolan (MZ) and Flumazenil (FL) and the influence of the clinical variables on the event rate.", "completion": "{\"entities\": [{\"text\": \"Midazolan\", \"type\": \"Chemical\"}, {\"text\": \"MZ\", \"type\": \"Chemical\"}, {\"text\": \"Flumazenil\", \"type\": \"Chemical\"}, {\"text\": \"FL\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04374", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Testosterone replacement in castrated DS rats increased BP, renal injury, and upregulation of renal angiotensinogen associated with HS diet.", "completion": "{\"entities\": [{\"text\": \"Testosterone\", \"type\": \"Chemical\"}, {\"text\": \"renal injury\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03698", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Of 20 patients evaluable for toxicity, four had stage III and 16 had stage IV disease.", "completion": "{\"entities\": [{\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01174", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Seven patients had been treated with anthracycline.", "completion": "{\"entities\": [{\"text\": \"anthracycline\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02439", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: HBsAg, anti - HBs, anti - HBc, and anti - HIV 1 / 2 were determined as part of routine diagnosis using Axsym assays (Abbott Laboratories, North Chicago, IL ). Serum samples were PCR amplified with HBV reverse transcriptase (RT) primers, followed by direct sequencing across the tyrosine - methionine - aspartate - aspartate (YMDD) motif of the major catalytic region in the C domain of the HBV RT enzyme.", "completion": "{\"entities\": [{\"text\": \"HBsAg\", \"type\": \"Chemical\"}, {\"text\": \"tyrosine\", \"type\": \"Chemical\"}, {\"text\": \"methionine\", \"type\": \"Chemical\"}, {\"text\": \"aspartate\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-05169", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The case of a nonepileptic patient who developed psychosis following phenytoin treatment for trigeminal neuralgia is described.", "completion": "{\"entities\": [{\"text\": \"psychosis\", \"type\": \"Disease\"}, {\"text\": \"phenytoin\", \"type\": \"Chemical\"}, {\"text\": \"trigeminal neuralgia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-reassigned-03623", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The Olanzipine HGGW Study Group.", "completion": "{\"entities\": [{\"text\": \"Olanzipine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02458", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Calcineurin - inhibitor therapy can lead to renal dysfunction in heart transplantation patients.", "completion": "{\"entities\": [{\"text\": \"renal dysfunction\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02296", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 48 cases / person - years of exposure ); 71.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03064", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 019 mol% of cytosine residues in DNA were substituted by the analogue, indicating that incorporation of 5-AzC occurs during repair synthesis.", "completion": "{\"entities\": [{\"text\": \"cytosine\", \"type\": \"Chemical\"}, {\"text\": \"5-AzC\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02257", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Sub - chronic GVG exposure inhibited the effect of cocaine for 3 days, which exceeded in magnitude and duration the identical acute dose.", "completion": "{\"entities\": [{\"text\": \"GVG\", \"type\": \"Chemical\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04072", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cardiac marker enzymes and antioxidative parameters in serum and heart tissues were measured.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-05208", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Therefore, old age may be a risk factor for developing this complication.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02685", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Drug-induced parkinsonism was observed in subjects treated with risperidone (42 %) and haloperidol (29 %) and was observed at occupancy levels above 60 %. Based on these observations, it is concluded that 5 - HT2 blockade obtained with risperidone", "completion": "{\"entities\": [{\"text\": \"Drug-induced parkinsonism\", \"type\": \"Disease\"}, {\"text\": \"risperidone\", \"type\": \"Chemical\"}, {\"text\": \"haloperidol\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01386", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pseudoacromegaly, on the other hand, is the presence of similar acromegaloid features in the absence of elevated growth hormone or insulin - like growth factor levels.", "completion": "{\"entities\": [{\"text\": \"Pseudoacromegaly\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03435", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Immunostaining for 7H6, not ZO - 1, decreased and predominantly appeared as discrete signals in the submembranous cytoplasm of periportal hepatocytes after BDL.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01552", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The patient' s symptoms improved slightly over the next few hours.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00703", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: She was not an alcoholic.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04927", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This effect was more relevant in patients treated with higher doses.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00236", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: administration were apparent earlier and sometimes lasted longer than those following oral administration.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02203", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Experimental design consisted of four groups: control (vehicle alone ), GSPE alone, drug alone and GSPE + drug.", "completion": "{\"entities\": [{\"text\": \"GSPE\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01845", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The low incidence of cerebral haemorrhage as a cause of death in patients with Parkinson's disease may reflect the hypotensive effect of levodopa and a hypotensive mechanism due to reduced noradrenaline levels in the parkinsonian", "completion": "{\"entities\": [{\"text\": \"cerebral haemorrhage\", \"type\": \"Disease\"}, {\"text\": \"death\", \"type\": \"Disease\"}, {\"text\": \"Parkinson's disease\", \"type\": \"Disease\"}, {\"text\": \"hypotensive\", \"type\": \"Disease\"}, {\"text\": \"levodopa\", \"type\": \"Chemical\"}, {\"text\": \"noradrenaline\", \"type\": \"Chemical\"}, {\"text\": \"parkinsonian\", \"type\": \"Disease\"}]}", "n_entities": 7}
{"ref": "bc5cdr-train-01466", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 8 ). The excess event rate was 1.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01082", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: High - dose 5-fluorouracil / folinic acid infusion therapy has recently become a popular regimen for various cancers", "completion": "{\"entities\": [{\"text\": \"5-fluorouracil\", \"type\": \"Chemical\"}, {\"text\": \"folinic acid\", \"type\": \"Chemical\"}, {\"text\": \"cancers\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02501", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Recovery of tacrolimus - associated brachial neuritis after conversion to everolimus in a pediatric renal transplant recipient -- case report and review of the literature.", "completion": "{\"entities\": [{\"text\": \"tacrolimus\", \"type\": \"Chemical\"}, {\"text\": \"brachial neuritis\", \"type\": \"Disease\"}, {\"text\": \"everolimus\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02450", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The purpose of this investigation was to extend these findings to a persistent pain model which could be distinguished from acute pain models on the basis of the nociceptive fibers activated, neurochemical substrates, and duration of the nociceptive stimulus.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"acute pain\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05189", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Glomerular epithelial protein 1 (GLEPP1) is a podocyte receptor membrane protein tyrosine phosphatase located on the apical cell membrane of visceral glomerular epithelial cell and foot processes.", "completion": "{\"entities\": [{\"text\": \"tyrosine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03596", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 mg / ml) were applied to the pial surface of the cortex of anaesthetized rats.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00357", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: She had no previous beta - blocking drug exposure.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04765", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The mechanism by which omeprazole caused the patient' s hemolytic anemia", "completion": "{\"entities\": [{\"text\": \"omeprazole\", \"type\": \"Chemical\"}, {\"text\": \"hemolytic anemia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02334", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: alpha3 +/- mice were partially resistant to nicotine - induced seizures when compared to wild - type littermates.", "completion": "{\"entities\": [{\"text\": \"nicotine\", \"type\": \"Chemical\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02513", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: OBJECTIVES: To estimate the frequency and severity of valvular heart abnormality and its possible reversibility after drug withdrawal in a case - control study.", "completion": "{\"entities\": [{\"text\": \"valvular heart abnormality\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02362", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cerebral haemorrhage induced by warfarin - the influence of drug - drug interactions.", "completion": "{\"entities\": [{\"text\": \"Cerebral haemorrhage\", \"type\": \"Disease\"}, {\"text\": \"warfarin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04199", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The time from transplant to baseline was similar in all patients.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04559", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Variant ventricular tachycardia in desipramine toxicity.", "completion": "{\"entities\": [{\"text\": \"ventricular tachycardia\", \"type\": \"Disease\"}, {\"text\": \"desipramine\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00269", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Some of the factors related to the clinical presentation and pathogenesis of the neuropathies", "completion": "{\"entities\": [{\"text\": \"neuropathies\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03716", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Granulocyte nadir was on day 14 (range, 4 - 22 ). Less frequent toxic effects included thrombocytopenia, anemia, nausea, mild alopecia, phlebitis, and mucositis.", "completion": "{\"entities\": [{\"text\": \"thrombocytopenia\", \"type\": \"Disease\"}, {\"text\": \"anemia\", \"type\": \"Disease\"}, {\"text\": \"nausea\", \"type\": \"Disease\"}, {\"text\": \"alopecia\", \"type\": \"Disease\"}, {\"text\": \"phlebitis\", \"type\": \"Disease\"}, {\"text\": \"mucositis\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-04713", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Survey of complications of indocyanine green angiography in Japan.", "completion": "{\"entities\": [{\"text\": \"indocyanine green\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00033", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Consequently, lithium pretreatment caused a fall in filtration fraction and an increase in fractional Li excretion.", "completion": "{\"entities\": [{\"text\": \"lithium\", \"type\": \"Chemical\"}, {\"text\": \"Li\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04252", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: As no other medications known to effect serum potassium had been given concomitantly, this course of events is suggestive of a cause - and - effect relationship between sulindac and hyperkalemia.", "completion": "{\"entities\": [{\"text\": \"potassium\", \"type\": \"Chemical\"}, {\"text\": \"sulindac\", \"type\": \"Chemical\"}, {\"text\": \"hyperkalemia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03877", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We suggest that our patient' s tubular dysfunction and myopathy may have resulted from mitochondrial dysfunction which is triggered by tacrolimus and augmented by lamivudine", "completion": "{\"entities\": [{\"text\": \"tubular dysfunction\", \"type\": \"Disease\"}, {\"text\": \"myopathy\", \"type\": \"Disease\"}, {\"text\": \"mitochondrial dysfunction\", \"type\": \"Disease\"}, {\"text\": \"tacrolimus\", \"type\": \"Chemical\"}, {\"text\": \"lamivudine\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-01675", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Our results failed to demonstrate an important response rate to single agent thalidomide in indolent lymphomas and contrast with the higher activity level reported with the second generation immunomodulatory agent, lenalidomide", "completion": "{\"entities\": [{\"text\": \"thalidomide\", \"type\": \"Chemical\"}, {\"text\": \"lymphomas\", \"type\": \"Disease\"}, {\"text\": \"lenalidomide\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03126", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The patient was taking 80 mg simvastatin at bedtime (initiated 27 days earlier ); amiodarone at a dose of 400 mg daily for 7 days, then 200 mg daily (initiated 19 days earlier ); and 400 mg atazanavir daily (initiated at least 2 years previously ). Laboratory evaluation revealed 66, 680 U / L creatine kinase, 93 mg / dL blood urea nitrogen, 4.", "completion": "{\"entities\": [{\"text\": \"simvastatin\", \"type\": \"Chemical\"}, {\"text\": \"amiodarone\", \"type\": \"Chemical\"}, {\"text\": \"atazanavir\", \"type\": \"Chemical\"}, {\"text\": \"creatine\", \"type\": \"Chemical\"}, {\"text\": \"blood urea nitrogen\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-00733", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Central retinal vein occlusion associated with clomiphene - induced ovulation.", "completion": "{\"entities\": [{\"text\": \"retinal vein occlusion\", \"type\": \"Disease\"}, {\"text\": \"clomiphene\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00374", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 75 %. The deformations caused by both coniine and nicotine sulfate were excessive flexion or extension of one or more toes.", "completion": "{\"entities\": [{\"text\": \"deformations\", \"type\": \"Disease\"}, {\"text\": \"coniine\", \"type\": \"Chemical\"}, {\"text\": \"nicotine\", \"type\": \"Chemical\"}, {\"text\": \"excessive flexion or extension of one or more toes\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02852", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05 ). Correlation with rating recall after one week was best when first - time ratings were requested as late as one day after injection (R (2 )= 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03808", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: NRA0160 and clozapine antagonized MAP - induced stereotyped behavior in mice, although their effects did not exceed 50% inhibition, even at the highest dose given.", "completion": "{\"entities\": [{\"text\": \"NRA0160\", \"type\": \"Chemical\"}, {\"text\": \"clozapine\", \"type\": \"Chemical\"}, {\"text\": \"MAP\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04591", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In all patients with variant angina, coronary spasm was provoked at a mean dose of 28 +/- 13 micrograms (mean +/- SD ). In the control group neither ischemic ST change nor localized spasm occurred.", "completion": "{\"entities\": [{\"text\": \"variant angina\", \"type\": \"Disease\"}, {\"text\": \"coronary spasm\", \"type\": \"Disease\"}, {\"text\": \"spasm\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01020", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We observed sinoatrial block due to chronic amiodarone administration in a 5 - year - old boy with primary cardiomyopathy, Wolff-Parkinson-White syndrome and supraventricular tachycardia.", "completion": "{\"entities\": [{\"text\": \"sinoatrial block\", \"type\": \"Disease\"}, {\"text\": \"amiodarone\", \"type\": \"Chemical\"}, {\"text\": \"primary cardiomyopathy\", \"type\": \"Disease\"}, {\"text\": \"Wolff-Parkinson-White syndrome\", \"type\": \"Disease\"}, {\"text\": \"supraventricular tachycardia\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-02024", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In 8 patients followed for 24 weeks, gallbladder contractility remained depressed throughout therapy.", "completion": "{\"entities\": [{\"text\": \"depressed\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02914", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Renal function remained normal in all patients.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01765", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 %/ 12h, suffering from depression diagnosed through DMS - III - R criteria, were included in the study.", "completion": "{\"entities\": [{\"text\": \"depression\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04817", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The bleeding ceased completely by the end of treatment and the patient remained free of hematuria thereafter.", "completion": "{\"entities\": [{\"text\": \"bleeding\", \"type\": \"Disease\"}, {\"text\": \"hematuria\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02249", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: An electroencephalogram showed continuous, generalized irregular slowing with admixed periodic triphasic waves indicating symptomatic encephalopathy.", "completion": "{\"entities\": [{\"text\": \"encephalopathy\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02463", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Proteinuria increased significantly from a median of 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-reassigned-01866", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Of the responders 72.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03742", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: With current treatment regimens including combined surgery, radiation and chemotherapy, the average life expectancy of the patients is limited to approximately 1 year.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04414", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 01% ethanol ). Cells were then treated with 30 ng / ml ritonavir or vehicle in the presence of aggregated LDL for 24 h.", "completion": "{\"entities\": [{\"text\": \"ethanol\", \"type\": \"Chemical\"}, {\"text\": \"ritonavir\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02102", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Twenty - three of the patients had previously taken appetite suppressants, mainly fenfluramines, as compared with only 5 of the controls (66 versus 6 %, p < 0.", "completion": "{\"entities\": [{\"text\": \"appetite suppressants\", \"type\": \"Chemical\"}, {\"text\": \"fenfluramines\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02798", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHOD: prospective study with 137 patients that underwent TEE with MZ associated to moderate sedation.", "completion": "{\"entities\": [{\"text\": \"MZ\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03922", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Patients received amifostine, 910 mg / m2 intravenously over 15 minutes.", "completion": "{\"entities\": [{\"text\": \"amifostine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00213", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pneumonitis with pleural and pericardial effusion and neuropathy during amiodarone therapy.", "completion": "{\"entities\": [{\"text\": \"pleural and pericardial effusion\", \"type\": \"Disease\"}, {\"text\": \"neuropathy\", \"type\": \"Disease\"}, {\"text\": \"amiodarone\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03603", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In contrast, FS containing aprotinin did not evoke any paroxysmal activity.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03343", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 2 million people in this country receive aminoglycoside antibiotics annually.", "completion": "{\"entities\": [{\"text\": \"aminoglycoside\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02581", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We have encountered several patients who developed substantial proteinuria associated with sirolimus use.", "completion": "{\"entities\": [{\"text\": \"proteinuria\", \"type\": \"Disease\"}, {\"text\": \"sirolimus\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02452", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: For comparison, tests were conducted in two acute pain models, the hotplate and warm water tail - withdrawal procedures.", "completion": "{\"entities\": [{\"text\": \"acute pain\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03317", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After 1 week of recovery, proteinuria was induced by adriamycin [1.", "completion": "{\"entities\": [{\"text\": \"proteinuria\", \"type\": \"Disease\"}, {\"text\": \"adriamycin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02387", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cardiac Angiography in Renally Impaired Patients (CARE) study: a randomized double - blind trial of contrast - induced nephropathy in patients with chronic kidney disease.", "completion": "{\"entities\": [{\"text\": \"nephropathy\", \"type\": \"Disease\"}, {\"text\": \"chronic kidney disease\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04460", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: MATERIALS AND METHODS: We investigated the causes of thrombotic microangiopathy during a 1 - year period, from June 2003 to June 2004, at the King Fahad National Guard Hospital in Riyadh, Saudi Arabia, by reviewing the slides of all transplant biopsies (n = 25) performed during this interval.", "completion": "{\"entities\": [{\"text\": \"thrombotic microangiopathy\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01633", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Considering that clozapine remains the gold standard in treatment of resistant psychosis, there is an urgent need to raise awareness among medical and paramedical staff involved in the care of these patients.", "completion": "{\"entities\": [{\"text\": \"clozapine\", \"type\": \"Chemical\"}, {\"text\": \"psychosis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00362", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The major teratogenic outcome is arthrogryposis, presumably due to nicotinic receptor blockade.", "completion": "{\"entities\": [{\"text\": \"arthrogryposis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02883", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In less than 1 hour after the ingestion of alcohol, he developed malaise with flushing of the face, tachycardia, and dyspnea.", "completion": "{\"entities\": [{\"text\": \"alcohol\", \"type\": \"Chemical\"}, {\"text\": \"flushing of the face\", \"type\": \"Disease\"}, {\"text\": \"tachycardia\", \"type\": \"Disease\"}, {\"text\": \"dyspnea\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03265", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Anti - oxidant effects of atorvastatin in dexamethasone - induced hypertension in the rat.", "completion": "{\"entities\": [{\"text\": \"atorvastatin\", \"type\": \"Chemical\"}, {\"text\": \"dexamethasone\", \"type\": \"Chemical\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01317", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: STUDY OBJECTIVE: We sought to compare the rate of akathisia after administration of intravenous prochlorperazine as a 2 - minute bolus or 15 - minute infusion.", "completion": "{\"entities\": [{\"text\": \"akathisia\", \"type\": \"Disease\"}, {\"text\": \"prochlorperazine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03571", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We investigated the safety and efficacy of adding different doses of ephedrine to propofol in order to obtund the hypotensive response.", "completion": "{\"entities\": [{\"text\": \"ephedrine\", \"type\": \"Chemical\"}, {\"text\": \"propofol\", \"type\": \"Chemical\"}, {\"text\": \"hypotensive\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00495", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Bladder retention of urine as a result of continuous intravenous infusion of fentanyl: 2 case reports.", "completion": "{\"entities\": [{\"text\": \"retention of urine\", \"type\": \"Disease\"}, {\"text\": \"fentanyl\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04065", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The density of hippocampal neurons in the brains of animals treated with BMCs was markedly preserved.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02980", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A good agreement was found between two independent observers (interclass correlation coefficient 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04866", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Patients were randomized in a 1: 1 ratio to receive the 4 - mg nicotine lozenge or 4 - mg nicotine gum.", "completion": "{\"entities\": [{\"text\": \"nicotine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05148", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The visual analog scale (VAS) was used to measure pain intensity and a stop - watch was used to time the pain period.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01810", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Randomized, double - blind trial of mazindol in Duchenne dystrophy.", "completion": "{\"entities\": [{\"text\": \"mazindol\", \"type\": \"Chemical\"}, {\"text\": \"Duchenne dystrophy\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03993", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Neuroactive steroids demonstrate pharmacological actions that have relevance for a host of neurological and psychiatric disorders.", "completion": "{\"entities\": [{\"text\": \"steroids\", \"type\": \"Chemical\"}, {\"text\": \"neurological and psychiatric disorders\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05200", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 001 ). In contrast, podocalyxin did not change significantly at this time.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01103", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: When both skin test and RAST for BPO were negative, single - blind, placebo - controlled challenge tests were done to ensure tolerance of PG or sensitivity to AX.", "completion": "{\"entities\": [{\"text\": \"BPO\", \"type\": \"Chemical\"}, {\"text\": \"PG\", \"type\": \"Chemical\"}, {\"text\": \"AX\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03224", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: All four agents were associated with aortic arch branching variants, although significantly increased only for Ro 40-5967 and verapamil", "completion": "{\"entities\": [{\"text\": \"Ro 40-5967\", \"type\": \"Chemical\"}, {\"text\": \"verapamil\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03098", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 025 ), but not for tyrosine hydroxylase in the surrounding catecholaminergic A10 region.", "completion": "{\"entities\": [{\"text\": \"tyrosine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02061", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We investigated an epidemic of liver disease in nine industrial workers who had had repeated accidental exposure to a mixture of 1,1-dichloro-2,2,2-trifluoroethane (HCFC 123) and 1-chloro-1,2,2,2-tetrafluoroethane (HCFC 124 ). All nine exposed workers were affected to various degrees.", "completion": "{\"entities\": [{\"text\": \"liver disease\", \"type\": \"Disease\"}, {\"text\": \"1,1-dichloro-2,2,2-trifluoroethane\", \"type\": \"Chemical\"}, {\"text\": \"HCFC 123\", \"type\": \"Chemical\"}, {\"text\": \"1-chloro-1,2,2,2-tetrafluoroethane\", \"type\": \"Chemical\"}, {\"text\": \"HCFC 124\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-reassigned-00717", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 001) after glutamate injection.", "completion": "{\"entities\": [{\"text\": \"glutamate\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01604", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: This study was undertaken as part of neonatal screening for hearing impairment and involved both ears of 200 newborns.", "completion": "{\"entities\": [{\"text\": \"hearing impairment\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05036", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 04 ). In addition, glomerular size was higher in the nitrendipine - treated group (14.", "completion": "{\"entities\": [{\"text\": \"nitrendipine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00316", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The cardiotoxic effects of adriamycin were studied in mammalian myocardial cells in culture as a model system.", "completion": "{\"entities\": [{\"text\": \"cardiotoxic\", \"type\": \"Disease\"}, {\"text\": \"adriamycin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00998", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Flow and metabolism were measured 5 - 13 days after the subarachnoid haemorrhage by a modification of the classical Kety - Schmidt technique using xenon - 133 i.", "completion": "{\"entities\": [{\"text\": \"subarachnoid haemorrhage\", \"type\": \"Disease\"}, {\"text\": \"xenon\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03934", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Surgical exploration revealed an iliopsoas hematoma and femoral nerve entrapment, resulting in a femoral nerve palsy and partial loss of quadriceps functions.", "completion": "{\"entities\": [{\"text\": \"hematoma\", \"type\": \"Disease\"}, {\"text\": \"nerve entrapment\", \"type\": \"Disease\"}, {\"text\": \"femoral nerve palsy\", \"type\": \"Disease\"}, {\"text\": \"partial loss of quadriceps functions\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-05126", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 006 ). Comparison of the mean ALT values revealed significantly higher mean alanine aminotransferase (ALT) values in the control group than the prophylactic lamivudine group; 154: 64 (p < 0.", "completion": "{\"entities\": [{\"text\": \"alanine\", \"type\": \"Chemical\"}, {\"text\": \"lamivudine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02617", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Efficacy and safety of asenapine in a placebo - and haloperidol - controlled trial in patients with acute exacerbation of schizophrenia.", "completion": "{\"entities\": [{\"text\": \"asenapine\", \"type\": \"Chemical\"}, {\"text\": \"haloperidol\", \"type\": \"Chemical\"}, {\"text\": \"schizophrenia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00674", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Responses of urinary strip preparations from control and cyclophosphamide - pretreated rats to electrical field stimulation and to agonists were assessed in the absence and presence of muscarinic, adrenergic and purinergic receptor antagonists.", "completion": "{\"entities\": [{\"text\": \"cyclophosphamide\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02317", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We conclude that noxious stimulation of facial mucosa increases intracranial blood flow and lacrimation via a trigemino - parasympathetic reflex.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03824", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Both agents show substantial clinical efficacy, with reductions in total cholesterol of over 30% and in LDL - cholesterol of 40% in clinical studies.", "completion": "{\"entities\": [{\"text\": \"cholesterol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02939", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Histopathology analyses in the 2 animals that died revealed liver and kidney toxicity, with greater severity in the orally - treated animal.", "completion": "{\"entities\": [{\"text\": \"liver and kidney toxicity\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02621", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 4) than placebo (- 10.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04118", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: Spironolactone - induced hyperkalemia and renal insufficiency", "completion": "{\"entities\": [{\"text\": \"Spironolactone\", \"type\": \"Chemical\"}, {\"text\": \"hyperkalemia\", \"type\": \"Disease\"}, {\"text\": \"renal insufficiency\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03188", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Consequently, carmofur - induced leukoencephalopathy may uncommonly result in organic personality syndrome in the residual state.", "completion": "{\"entities\": [{\"text\": \"carmofur\", \"type\": \"Chemical\"}, {\"text\": \"leukoencephalopathy\", \"type\": \"Disease\"}, {\"text\": \"organic personality syndrome\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01596", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A similar bradycardic effect of clonidine was observed in isolated spontaneously beating right atria from alpha2ABC - knockout and wild - type mice.", "completion": "{\"entities\": [{\"text\": \"clonidine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00390", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The hypotensive drug was discontinued at the completion of the operative procedure.", "completion": "{\"entities\": [{\"text\": \"hypotensive\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01356", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Specifically, WSP mice may have lower sensitivity to cholinergic convulsants", "completion": "{\"entities\": [{\"text\": \"convulsants\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04087", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Acute hepatitis attack after exposure to telithromycin.", "completion": "{\"entities\": [{\"text\": \"hepatitis\", \"type\": \"Disease\"}, {\"text\": \"telithromycin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00976", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Mean arterial pressure was decreased to 50 mm Hg for 30 minutes either by hemorrhage (HEM, n = 7) or by continuous infusion of sodium nitroprusside (SNP, n = 7 ). During HEM - induced hypotension the cardiac output was significantly lower and systemic vascular resistance higher compared with that in the SNP group.", "completion": "{\"entities\": [{\"text\": \"hemorrhage\", \"type\": \"Disease\"}, {\"text\": \"HEM\", \"type\": \"Disease\"}, {\"text\": \"sodium nitroprusside\", \"type\": \"Chemical\"}, {\"text\": \"SNP\", \"type\": \"Chemical\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-05124", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the prophylactic lamivudine group severe hepatitis were observed only in 1 patient (2.", "completion": "{\"entities\": [{\"text\": \"lamivudine\", \"type\": \"Chemical\"}, {\"text\": \"hepatitis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00794", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These results elucidated ecstasy - related deficits, only some of which might be attributed to cannabis use.", "completion": "{\"entities\": [{\"text\": \"ecstasy\", \"type\": \"Chemical\"}, {\"text\": \"cannabis\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05174", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The results indicated that concomitant treatment with gum Arabic and GM significantly increased creatinine and urea by about 183 and 239 %, respectively (compared to 432 and 346 %, respectively, in rats treated with cellulose and GM ), and decreased that of cortical GSH by 21 %(compared to 27% in the cellulose plus GM group) The GM - induced proximal tubular necrosis appeared to be slightly less severe in rats given GM together with gum Arabic than in those given GM and cellulose.", "completion": "{\"entities\": [{\"text\": \"gum Arabic\", \"type\": \"Chemical\"}, {\"text\": \"GM\", \"type\": \"Chemical\"}, {\"text\": \"creatinine\", \"type\": \"Chemical\"}, {\"text\": \"urea\", \"type\": \"Chemical\"}, {\"text\": \"GSH\", \"type\": \"Chemical\"}, {\"text\": \"tubular necrosis\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-03531", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: Cardiac troponins I (cTnI) and T (cTnT) have been shown to be highly sensitive and specific markers of myocardial cell injury.", "completion": "{\"entities\": [{\"text\": \"myocardial cell injury\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02129", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, TAM induces release of peripheral proteins of membrane - cytoskeleton and cytosol proteins essentially bound to band 3.", "completion": "{\"entities\": [{\"text\": \"TAM\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02432", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: While small prospective studies have not revealed any significant drug - drug interaction between warfarin and levofloxacin, several case reports have indicated that levofloxacin may significantly potentiate the anticoagulation effect of warfarin.", "completion": "{\"entities\": [{\"text\": \"warfarin\", \"type\": \"Chemical\"}, {\"text\": \"levofloxacin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04912", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Two mouse lines were selectively bred according to their sensitivity (BS line) or resistance (BR line) to seizures induced by a single i.", "completion": "{\"entities\": [{\"text\": \"seizures\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00301", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Total cell yields from DES - treated pituitaries increased from 1.", "completion": "{\"entities\": [{\"text\": \"DES\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05118", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The prophylactic lamivudin group consisted of 37 patients who received prophylactic lamivudine treatment.", "completion": "{\"entities\": [{\"text\": \"lamivudin\", \"type\": \"Chemical\"}, {\"text\": \"lamivudine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02459", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The novel immunosuppressive (IS) drug sirolmus (Srl) lacks nephrotoxic effects; however, proteinuria associated with Srl has been reported following renal transplantation.", "completion": "{\"entities\": [{\"text\": \"sirolmus\", \"type\": \"Chemical\"}, {\"text\": \"Srl\", \"type\": \"Chemical\"}, {\"text\": \"nephrotoxic\", \"type\": \"Disease\"}, {\"text\": \"proteinuria\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01540", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cauda equina syndrome is a rare complication of epidural anesthesia.", "completion": "{\"entities\": [{\"text\": \"Cauda equina syndrome\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01215", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Chronic FK506 nephropathy consisted of rough and foamy tubular vacuolization (5 biopsies ), arteriolopathy (angiodegeneration of the arteriolar wall; 20 biopsies ), focal segmental glomerulosclerosis (4 biopsies) and the striped form of interstitial fibrosis (11 biopsies ). The serum creatinine levels of patients in the mild - type chronic FK506 nephropathy group, which included 7 episode biopsies, were statistically higher than those in the minimum - type chronic FK506 - nephropathy group (P < 0.", "completion": "{\"entities\": [{\"text\": \"FK506\", \"type\": \"Chemical\"}, {\"text\": \"nephropathy\", \"type\": \"Disease\"}, {\"text\": \"focal segmental glomerulosclerosis\", \"type\": \"Disease\"}, {\"text\": \"interstitial fibrosis\", \"type\": \"Disease\"}, {\"text\": \"creatinine\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-05082", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: PATIENTS AND METHODS: The randomized sample consisted of 234 euthymic men who were receiving some type of SSRI.", "completion": "{\"entities\": [{\"text\": \"SSRI\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02097", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: High incidence of primary pulmonary hypertension associated with appetite suppressants in Belgium.", "completion": "{\"entities\": [{\"text\": \"primary pulmonary hypertension\", \"type\": \"Disease\"}, {\"text\": \"appetite suppressants\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04360", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, it is not known that how pain intensity ratings are affected by attention in capsaicin - induced secondary hyperalgesia.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"capsaicin\", \"type\": \"Chemical\"}, {\"text\": \"hyperalgesia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00185", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 4% of the German population, may experience adverse drug reactions", "completion": "{\"entities\": [{\"text\": \"adverse drug reactions\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03928", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Six partial responses were observed for an overall response rate of 16 %. Most patients (57 %) stopped treatment because of disease progression.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02457", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Development of proteinuria after switch to sirolimus - based immunosuppression in long - term cardiac transplant patients.", "completion": "{\"entities\": [{\"text\": \"proteinuria\", \"type\": \"Disease\"}, {\"text\": \"sirolimus\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03249", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 8% sevoflurane, indicating a celling effect.", "completion": "{\"entities\": [{\"text\": \"sevoflurane\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03439", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: OBJECTIVE: The objective of this study was to identify the incidence and to monitor the progression of hearing loss in children and young adults with beta-thalassemia major.", "completion": "{\"entities\": [{\"text\": \"hearing loss\", \"type\": \"Disease\"}, {\"text\": \"beta-thalassemia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00972", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Both patients recovered quickly after stopping glyburide therapy and have remained well for a follow - up period of 1 year.", "completion": "{\"entities\": [{\"text\": \"glyburide\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00451", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Patients received a minimum of three courses unless progressive disease was detected.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03032", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Hunt and Hess grade (P < 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03425", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: They should be closely observed and should be given reduced doses of cimetidine", "completion": "{\"entities\": [{\"text\": \"cimetidine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00010", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Suxamethonium infusion rate and observed fasciculations.", "completion": "{\"entities\": [{\"text\": \"Suxamethonium\", \"type\": \"Chemical\"}, {\"text\": \"fasciculations\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04287", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: They were given a ten day pretreatment with either L-alpha-GFC or placebo, p.", "completion": "{\"entities\": [{\"text\": \"L-alpha-GFC\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02761", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 3 min from the literature.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02032", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This study suggests that administration of low doses of beta - blockers may improve levodopa - induced ballistic and choreic dyskinesia in PD", "completion": "{\"entities\": [{\"text\": \"levodopa\", \"type\": \"Chemical\"}, {\"text\": \"dyskinesia\", \"type\": \"Disease\"}, {\"text\": \"PD\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02700", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Oral manifestations of\" meth mouth \": a case report.", "completion": "{\"entities\": [{\"text\": \"meth mouth\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01980", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The optimal rat size to begin phenobarbitone was determined as 100 g, and this size as a group had a mean maximum relative liver weight increase 47% greater than normal rats of the same body weight.", "completion": "{\"entities\": [{\"text\": \"phenobarbitone\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00346", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Two groups of supine subjects were studied under placebo - controlled conditions, one during the night, when sleeping (n = 7) and the other at daytime, when awake (n = 6 ). Each subject received a single 50 mg dose of clomipramine given orally 2 hours before blood collection.", "completion": "{\"entities\": [{\"text\": \"clomipramine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01885", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the pre - treatment evaluation, signs of cardiovascular disease were found in 33 patients (43 %). During treatment, adverse cardiac effects were observed in 14 patients (18 %). The mean age of these patients was the same as for the entire group, 64 years.", "completion": "{\"entities\": [{\"text\": \"cardiovascular disease\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03597", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The response of the animals was evaluated using electroencephalography and by monitoring the clinical behaviour during and after recovery from anaesthesia.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04787", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSION: This is the first study in the literature investigating a link between angiogenesis soluble markers and ribavirin induced anemia in patients with hepatitis C and we could not find any relation.", "completion": "{\"entities\": [{\"text\": \"ribavirin\", \"type\": \"Chemical\"}, {\"text\": \"anemia\", \"type\": \"Disease\"}, {\"text\": \"hepatitis C\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01313", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The clinical course and histopathological results of the two cases are presented.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04901", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: g ., dyskinesia developed no sooner than 146 days of chronic levodopa administration ). All animals were similarly symptomatic at the start of levodopa treatment and had similar therapeutic responses to the drug.", "completion": "{\"entities\": [{\"text\": \"dyskinesia\", \"type\": \"Disease\"}, {\"text\": \"levodopa\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00851", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The present study aimed to investigate the effects of pallidal neurotensin on haloperidol - induced parkinsonian symptoms.", "completion": "{\"entities\": [{\"text\": \"neurotensin\", \"type\": \"Chemical\"}, {\"text\": \"haloperidol\", \"type\": \"Chemical\"}, {\"text\": \"parkinsonian symptoms\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02326", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These data support the hypothesis that SE - induced mossy fiber sprouting and synaptic reorganization are relevant characteristics of seizure development in these murine strains, resembling rat models of human temporal lobe epilepsy", "completion": "{\"entities\": [{\"text\": \"SE\", \"type\": \"Disease\"}, {\"text\": \"seizure\", \"type\": \"Disease\"}, {\"text\": \"temporal lobe epilepsy\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04506", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Our objective was to investigate brain MR imaging findings and the utility of diffusion - weighted (DW) imaging in organ transplant patients who developed neurologic symptoms during tacrolimus therapy.", "completion": "{\"entities\": [{\"text\": \"tacrolimus\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04571", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These were the albino Sprague - Dawley ICR and BALB / C, the black C57BL / 6 and the brown CDF - I mouse strains.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04060", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Prevention of seizures and reorganization of hippocampal functions by transplantation of bone marrow cells in the acute phase of experimental epilepsy.", "completion": "{\"entities\": [{\"text\": \"seizures\", \"type\": \"Disease\"}, {\"text\": \"epilepsy\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04749", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Carbamazepine and vigabatrin are contraindicated in typical absence seizures.", "completion": "{\"entities\": [{\"text\": \"Carbamazepine\", \"type\": \"Chemical\"}, {\"text\": \"vigabatrin\", \"type\": \"Chemical\"}, {\"text\": \"absence seizures\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01417", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Although the United States Food and Drug Administration banned its use for nocturnal leg cramps due to lack of safety and efficacy, quinine is widely available in beverages including tonic water and bitter lemon.", "completion": "{\"entities\": [{\"text\": \"nocturnal leg cramps\", \"type\": \"Disease\"}, {\"text\": \"quinine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02520", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 8) and mitral regurgitation (OR: 10.", "completion": "{\"entities\": [{\"text\": \"mitral regurgitation\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04143", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, an increase of serum creatinine at various times postoperatively is more predictive of the development of CRF or ESRD", "completion": "{\"entities\": [{\"text\": \"creatinine\", \"type\": \"Chemical\"}, {\"text\": \"CRF\", \"type\": \"Disease\"}, {\"text\": \"ESRD\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03521", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The images were subsequently processed to obtain volumetric data for the cerebellum.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-reassigned-04914", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 88) and acetaminophen 1.", "completion": "{\"entities\": [{\"text\": \"acetaminophen\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00732", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSION: Higher OD is associated with significant risk of subsequent thrombosis in patients with isolated - HIT", "completion": "{\"entities\": [{\"text\": \"thrombosis\", \"type\": \"Disease\"}, {\"text\": \"HIT\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04053", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The results suggest that a prolonged combination of more than 120 min of PGE1 - induced hypotension and moderate haemodilution would cause impairment of hepatic function", "completion": "{\"entities\": [{\"text\": \"PGE1\", \"type\": \"Chemical\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}, {\"text\": \"haemodilution\", \"type\": \"Disease\"}, {\"text\": \"impairment of hepatic function\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00232", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Plasma concentrations of the drug were estimated by gas - liquid chromatography, in a smaller number of the subjects.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01258", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In female rats, only a weak tendency toward aggressiveness was found.", "completion": "{\"entities\": [{\"text\": \"aggressiveness\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02870", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Repetitive transcranial magnetic stimulation for levodopa - induced dyskinesias in Parkinson's disease.", "completion": "{\"entities\": [{\"text\": \"levodopa\", \"type\": \"Chemical\"}, {\"text\": \"dyskinesias\", \"type\": \"Disease\"}, {\"text\": \"Parkinson's disease\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03123", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Severe rhabdomyolysis and acute renal failure secondary to concomitant use of simvastatin, amiodarone, and atazanavir.", "completion": "{\"entities\": [{\"text\": \"rhabdomyolysis\", \"type\": \"Disease\"}, {\"text\": \"acute renal failure\", \"type\": \"Disease\"}, {\"text\": \"simvastatin\", \"type\": \"Chemical\"}, {\"text\": \"amiodarone\", \"type\": \"Chemical\"}, {\"text\": \"atazanavir\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-01547", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Three hours later, she complained of perineal numbness and lower extremity weakness.", "completion": "{\"entities\": [{\"text\": \"numbness\", \"type\": \"Disease\"}, {\"text\": \"lower extremity weakness\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-00558", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: kg - 1 + fentanyl 0.", "completion": "{\"entities\": [{\"text\": \"fentanyl\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03739", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The in vitro data suggest that the site responsible for the decrease in seizure activity 24 h after gamma-HCH may be the GABA", "completion": "{\"entities\": [{\"text\": \"seizure\", \"type\": \"Disease\"}, {\"text\": \"gamma-HCH\", \"type\": \"Chemical\"}, {\"text\": \"GABA\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03017", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This type of lesion broadens the spectrum of liver injury due to this drug combination, mainly represented by a benign cholestatic syndrome.", "completion": "{\"entities\": [{\"text\": \"liver injury\", \"type\": \"Disease\"}, {\"text\": \"cholestatic syndrome\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01116", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Neuromuscular blocking agents (NMBAs) are often used for patients requiring prolonged mechanical ventilation.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00934", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 3, whereas those estimated for\" late\" damage (based on morphological cardiac and renal lesions) varied between 2.", "completion": "{\"entities\": [{\"text\": \"cardiac and renal lesions\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01158", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CY caused hemorrhagic cystitis in 40% of rats, but it did not cause this complication when combined with 5-FU and MTX.", "completion": "{\"entities\": [{\"text\": \"CY\", \"type\": \"Chemical\"}, {\"text\": \"hemorrhagic cystitis\", \"type\": \"Disease\"}, {\"text\": \"5-FU\", \"type\": \"Chemical\"}, {\"text\": \"MTX\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03110", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: The possible role of alcohol in the development of hepatotoxicity associated with therapeutic doses of paracetamol (acetaminophen) is currently debated.", "completion": "{\"entities\": [{\"text\": \"alcohol\", \"type\": \"Chemical\"}, {\"text\": \"hepatotoxicity\", \"type\": \"Disease\"}, {\"text\": \"paracetamol\", \"type\": \"Chemical\"}, {\"text\": \"acetaminophen\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04643", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 9 mg / l carbachol, respectively.", "completion": "{\"entities\": [{\"text\": \"carbachol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00158", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Marital unhappiness, as indicated by AMHS scores, was not associated with arthritis but was associated with sexual dysfunction", "completion": "{\"entities\": [{\"text\": \"arthritis\", \"type\": \"Disease\"}, {\"text\": \"sexual dysfunction\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03511", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05) occurred more frequently in patients who had a morphine infusion.", "completion": "{\"entities\": [{\"text\": \"morphine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03202", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Regional localization of the antagonism of amphetamine - induced hyperactivity by intracerebral calcitonin injections.", "completion": "{\"entities\": [{\"text\": \"amphetamine\", \"type\": \"Chemical\"}, {\"text\": \"hyperactivity\", \"type\": \"Disease\"}, {\"text\": \"calcitonin\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04739", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: INTRODUCTION: Cyclophosphamide is an alkylating agent given frequently as a component of many conditioning regimens.", "completion": "{\"entities\": [{\"text\": \"Cyclophosphamide\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01879", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Adverse cardiac effects during induction chemotherapy treatment with cis-platin and 5-fluorouracil.", "completion": "{\"entities\": [{\"text\": \"cis-platin\", \"type\": \"Chemical\"}, {\"text\": \"5-fluorouracil\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03444", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Patients were followed for 8 - 14 years.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00739", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULT (S ): A 36 - year - old Chinese woman developed central retinal vein occlusion after eight courses of CC.", "completion": "{\"entities\": [{\"text\": \"retinal vein occlusion\", \"type\": \"Disease\"}, {\"text\": \"CC\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05138", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We conclude that Rg1 may significantly improve the spatial learning capacity impaired by chonic morphine administration and restore the morphine - inhibited LTP.", "completion": "{\"entities\": [{\"text\": \"Rg1\", \"type\": \"Chemical\"}, {\"text\": \"morphine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02998", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A 30 - year old Caucasian man reported with abdominal pain and jaundice after 3 - day administration of oral ciprofloxacin for a suspect of urinary tract infection.", "completion": "{\"entities\": [{\"text\": \"abdominal pain\", \"type\": \"Disease\"}, {\"text\": \"jaundice\", \"type\": \"Disease\"}, {\"text\": \"ciprofloxacin\", \"type\": \"Chemical\"}, {\"text\": \"urinary tract infection\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04925", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 50 mg / kg) was given to 10 cancer patients whose pain was unrelieved by morphine in a randomized, double - blind, crossover, double - dose study.", "completion": "{\"entities\": [{\"text\": \"cancer\", \"type\": \"Disease\"}, {\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"morphine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02844", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Subjects also recalled their pains one week later.", "completion": "{\"entities\": [{\"text\": \"pains\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03489", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: All rats in the sodium - depleted group had histopathological evidence of patchy tubular cytoplasmic degeneration in tubules that was not observed in any normal - salt or salt - loaded rat.", "completion": "{\"entities\": [{\"text\": \"sodium\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-reassigned-04418", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 003) and control (1.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03772", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The ACTIVE - W (Atrial Fibrillation Clopidogrel Trial with Irbesartan for Prevention of Vascular Events) study has demonstrated that warfarin is superior to platelet therapy (clopidogrel plus aspirin) in the prevention af embolic events.", "completion": "{\"entities\": [{\"text\": \"Atrial Fibrillation\", \"type\": \"Disease\"}, {\"text\": \"Clopidogrel\", \"type\": \"Chemical\"}, {\"text\": \"Irbesartan\", \"type\": \"Chemical\"}, {\"text\": \"warfarin\", \"type\": \"Chemical\"}, {\"text\": \"clopidogrel\", \"type\": \"Chemical\"}, {\"text\": \"aspirin\", \"type\": \"Chemical\"}, {\"text\": \"embolic events\", \"type\": \"Disease\"}]}", "n_entities": 7}
{"ref": "bc5cdr-train-00076", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The magnesium was stopped and she recovered over a few days.", "completion": "{\"entities\": [{\"text\": \"magnesium\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02320", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Recurrent excitation in the dentate gyrus of a murine model of temporal lobe epilepsy.", "completion": "{\"entities\": [{\"text\": \"temporal lobe epilepsy\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01274", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: An association has been found between transplant glomerulopathy (TG) and reduplication of peritubular capillary basement membranes (PTCR ). Although such an association is of practical and theoretical importance, only one prospective study has tried to confirm it.", "completion": "{\"entities\": [{\"text\": \"transplant glomerulopathy\", \"type\": \"Disease\"}, {\"text\": \"TG\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03704", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Two pathologic complete responses were observed in patients who had achieved clinical complete responses.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01500", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Significant blockade of cocaine toxicity was observed with the higher dose of GNC92H2 (190 mg / kg ), where premorbid behaviors were reduced up to 40 %, seizures up to 77% and death by 72 %. Importantly, GNC92H2 prevented death even post - cocaine injection.", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}, {\"text\": \"GNC92H2\", \"type\": \"Chemical\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}, {\"text\": \"death\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-02899", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A question arises whether the reuptake inhibition is of any importance to the adaptive changes induced by repeated antidepressants, suggested to be responsible for the antidepressant", "completion": "{\"entities\": [{\"text\": \"antidepressant\", \"type\": \"Chemical\"}, {\"text\": \"antidepressants\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01032", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: At autopsy the liver was enlarged and firm with signs of venous congestion.", "completion": "{\"entities\": [{\"text\": \"venous congestion\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03668", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 4 ), and cleft lip with cleft palate (AOR = 2.", "completion": "{\"entities\": [{\"text\": \"cleft lip\", \"type\": \"Disease\"}, {\"text\": \"cleft palate\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05075", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: d - 1) prevented FK 506 - induced hypertension in rats.", "completion": "{\"entities\": [{\"text\": \"FK 506\", \"type\": \"Chemical\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04336", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5M CaCl(2) or normal saline (NaCl ). After 12weeks, animals were euthanized, and CaCl(2) - treated, CaCl(2) - untreated (n = 12) and NaCl - treated aortic segments (n = 12) were collected for histological and molecular assessments.", "completion": "{\"entities\": [{\"text\": \"CaCl(2)\", \"type\": \"Chemical\"}, {\"text\": \"NaCl\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01942", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: PEG 400 impressively decreased both acute high - dose and chronic low - dose - ADR - associated lethality.", "completion": "{\"entities\": [{\"text\": \"PEG 400\", \"type\": \"Chemical\"}, {\"text\": \"ADR\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00261", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 6 %), accounting for half of the cases with motor neuropathy.", "completion": "{\"entities\": [{\"text\": \"motor neuropathy\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05159", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Reserpine injection (one dose of 1 mg / kg s.", "completion": "{\"entities\": [{\"text\": \"Reserpine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00959", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Stroke associated with cocaine use.", "completion": "{\"entities\": [{\"text\": \"Stroke\", \"type\": \"Disease\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04397", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Sulpiride did not affect the magnitude of a steroid - induced LH surge or the percentage of GnRH neurons activated during the surge.", "completion": "{\"entities\": [{\"text\": \"Sulpiride\", \"type\": \"Chemical\"}, {\"text\": \"steroid\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04276", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Possible intramuscular midazolam - associated cardiorespiratory arrest and death.", "completion": "{\"entities\": [{\"text\": \"midazolam\", \"type\": \"Chemical\"}, {\"text\": \"cardiorespiratory arrest\", \"type\": \"Disease\"}, {\"text\": \"death\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03052", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These seven cases demonstrate that procainamide can produce an acquired prolonged Q-T syndrome with polymorphous ventricular tachycardia", "completion": "{\"entities\": [{\"text\": \"procainamide\", \"type\": \"Chemical\"}, {\"text\": \"prolonged Q-T syndrome\", \"type\": \"Disease\"}, {\"text\": \"ventricular tachycardia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03990", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Unlike DFU, piroxicam was also highly toxic to the dams.", "completion": "{\"entities\": [{\"text\": \"DFU\", \"type\": \"Chemical\"}, {\"text\": \"piroxicam\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01833", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: pentoxifylline (p less than 0.", "completion": "{\"entities\": [{\"text\": \"pentoxifylline\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02522", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 1 - 53) were more frequent in PD patients (tricuspid: NS ). The number of affected valves (n = 2.", "completion": "{\"entities\": [{\"text\": \"PD\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04030", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Ketoconazole was introduced in the United Kingdom in 1981.", "completion": "{\"entities\": [{\"text\": \"Ketoconazole\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00555", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Our patients developed jaundice following treatment with ticlopidine and showed the clinical and laboratory characteristics of cholestatic hepatitis, which resolved after discontinuation of the drug.", "completion": "{\"entities\": [{\"text\": \"jaundice\", \"type\": \"Disease\"}, {\"text\": \"ticlopidine\", \"type\": \"Chemical\"}, {\"text\": \"cholestatic hepatitis\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00216", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Immediate but gradual improvement followed withdrawal of amiodarone and treatment with prednisolone.", "completion": "{\"entities\": [{\"text\": \"amiodarone\", \"type\": \"Chemical\"}, {\"text\": \"prednisolone\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03614", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: D-penicillamine - induced angiopathy in rats.", "completion": "{\"entities\": [{\"text\": \"D-penicillamine\", \"type\": \"Chemical\"}, {\"text\": \"angiopathy\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-05826", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Blood cultures revealed S.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02514", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: All PD patients in the Amiens area treated with pergolide were invited to attend a cardiologic assessment including transthoracic echocardiography.", "completion": "{\"entities\": [{\"text\": \"PD\", \"type\": \"Disease\"}, {\"text\": \"pergolide\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03789", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A 3 - year - old girl had behavioral deterioration, with hyperkinesis, irritability, and sleeping difficulties after the therapeutic administration of isoniazid.", "completion": "{\"entities\": [{\"text\": \"behavioral deterioration\", \"type\": \"Disease\"}, {\"text\": \"hyperkinesis\", \"type\": \"Disease\"}, {\"text\": \"irritability\", \"type\": \"Disease\"}, {\"text\": \"sleeping difficulties\", \"type\": \"Disease\"}, {\"text\": \"isoniazid\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-05052", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In a few cases the presence of active denervation signified a poor prognosis, with only slight improvement.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01441", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In sham - operated rats, rilmenidine or alpha-methyldopa elicited similar hypotension that lasted at least 5 h and was associated with reductions in standard deviation of mean arterial pressure.", "completion": "{\"entities\": [{\"text\": \"rilmenidine\", \"type\": \"Chemical\"}, {\"text\": \"alpha-methyldopa\", \"type\": \"Chemical\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03680", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: There have been several long - term studies of patients with rheumatoid arthritis treated with azathioprine and cyclophosphamide and the incidence of most of the common cancers is not increased.", "completion": "{\"entities\": [{\"text\": \"rheumatoid arthritis\", \"type\": \"Disease\"}, {\"text\": \"azathioprine\", \"type\": \"Chemical\"}, {\"text\": \"cyclophosphamide\", \"type\": \"Chemical\"}, {\"text\": \"cancers\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01087", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: of the patients showed any clinical deteriotation during the following 3 - 6 months.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00012", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Suxamethonium chloride (Sch) was administered i.", "completion": "{\"entities\": [{\"text\": \"Suxamethonium chloride\", \"type\": \"Chemical\"}, {\"text\": \"Sch\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03088", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Hypersensitivity to carbamazepine presenting with a leukemoid reaction, eosinophilia, erythroderma, and renal failure.", "completion": "{\"entities\": [{\"text\": \"Hypersensitivity\", \"type\": \"Disease\"}, {\"text\": \"carbamazepine\", \"type\": \"Chemical\"}, {\"text\": \"leukemoid reaction\", \"type\": \"Disease\"}, {\"text\": \"eosinophilia\", \"type\": \"Disease\"}, {\"text\": \"erythroderma\", \"type\": \"Disease\"}, {\"text\": \"renal failure\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-01211", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Clinical and histopathologic examination of renal allografts treated with tacrolimus (FK506) for at least one year.", "completion": "{\"entities\": [{\"text\": \"tacrolimus\", \"type\": \"Chemical\"}, {\"text\": \"FK506\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05215", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Similarly, pre - test scopolamine partially reversed the scopolamine - induced amnesia, but not significantly; and pre - test cycloheximide failed to reverse the cycloheximide - induced amnesia.", "completion": "{\"entities\": [{\"text\": \"scopolamine\", \"type\": \"Chemical\"}, {\"text\": \"amnesia\", \"type\": \"Disease\"}, {\"text\": \"cycloheximide\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01793", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This study describes neuropsychiatric side effects in patients after treatment with mefloquine.", "completion": "{\"entities\": [{\"text\": \"mefloquine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01260", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Serotonergic antidepressants and urinary incontinence.", "completion": "{\"entities\": [{\"text\": \"Serotonergic antidepressants\", \"type\": \"Chemical\"}, {\"text\": \"urinary incontinence\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05141", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: AIM: This study was carried out to determine the effect of injection duration on bruising and pain following the administration of the subcutaneous injection of heparin.", "completion": "{\"entities\": [{\"text\": \"bruising\", \"type\": \"Disease\"}, {\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"heparin\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01267", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Hypotension following the initiation of tizanidine in a patient treated with an angiotensin converting enzyme inhibitor for chronic hypertension.", "completion": "{\"entities\": [{\"text\": \"Hypotension\", \"type\": \"Disease\"}, {\"text\": \"tizanidine\", \"type\": \"Chemical\"}, {\"text\": \"angiotensin\", \"type\": \"Chemical\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01623", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This study provides a useful animal model for understanding the neuropathological processes underlying autism spectrum disorders", "completion": "{\"entities\": [{\"text\": \"autism spectrum disorders\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04245", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Hyperkalemia associated with sulindac therapy.", "completion": "{\"entities\": [{\"text\": \"Hyperkalemia\", \"type\": \"Disease\"}, {\"text\": \"sulindac\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00634", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: She then very rapidly developed acute onset of severe facial and extremity tetany.", "completion": "{\"entities\": [{\"text\": \"tetany\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04244", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The beneficial effect of Adriamycin", "completion": "{\"entities\": [{\"text\": \"Adriamycin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03105", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In 19 of the 40 patients perfusion defects compatible with ischemia were detected on SPECT.", "completion": "{\"entities\": [{\"text\": \"ischemia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03306", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Response rates according to three sets of criteria were greater with the standard dose (55 %- 60 %) than the low dose (25 %- 35 %) and placebo (25 %- 30 %). The advantage of standard dose over low dose was replicated in phase B.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01913", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The correlation between neuropathic damage and inhibition of neurotoxic esterase or neuropathy target enzyme (NTE) was examined in rats acutely exposed to Mipafox (N, N'-diisopropylphosphorodiamidofluoridate ), a neurotoxic organophosphate.", "completion": "{\"entities\": [{\"text\": \"neuropathic damage\", \"type\": \"Disease\"}, {\"text\": \"neurotoxic\", \"type\": \"Disease\"}, {\"text\": \"neuropathy\", \"type\": \"Disease\"}, {\"text\": \"Mipafox\", \"type\": \"Chemical\"}, {\"text\": \"N, N'-diisopropylphosphorodiamidofluoridate\", \"type\": \"Chemical\"}, {\"text\": \"organophosphate\", \"type\": \"Chemical\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-02327", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The alpha3 and beta4 nicotinic acetylcholine receptor subunits are necessary for nicotine - induced seizures and hypolocomotion in mice.", "completion": "{\"entities\": [{\"text\": \"acetylcholine\", \"type\": \"Chemical\"}, {\"text\": \"nicotine\", \"type\": \"Chemical\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}, {\"text\": \"hypolocomotion\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-05076", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These results indicate that FK 506 may increase blood pressure not only by increasing ET - 1 production but also by decreasing NO", "completion": "{\"entities\": [{\"text\": \"FK 506\", \"type\": \"Chemical\"}, {\"text\": \"NO\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03127", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 6 mg / dL creatinine, 1579 U / L aspartate aminotransferase, and 738 U / L alanine aminotransferase.", "completion": "{\"entities\": [{\"text\": \"creatinine\", \"type\": \"Chemical\"}, {\"text\": \"aspartate\", \"type\": \"Chemical\"}, {\"text\": \"alanine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01166", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: We report seven cases where substitution of lithium, either fully or partially, with divalproex sodium was extremely helpful in reducing the cognitive, motivational, or creative deficits attributed to lithium in our bipolar patients.", "completion": "{\"entities\": [{\"text\": \"lithium\", \"type\": \"Chemical\"}, {\"text\": \"divalproex sodium\", \"type\": \"Chemical\"}, {\"text\": \"cognitive, motivational, or creative deficits\", \"type\": \"Disease\"}, {\"text\": \"bipolar\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01487", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Clinical and experimental studies also suggest that situations causing gallbladder dysfunction, such as fasting, may have a role for the development of pseudolithiasis.", "completion": "{\"entities\": [{\"text\": \"gallbladder dysfunction\", \"type\": \"Disease\"}, {\"text\": \"pseudolithiasis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00442", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These results suggest that antithrombosis of TET and FAN", "completion": "{\"entities\": [{\"text\": \"TET\", \"type\": \"Chemical\"}, {\"text\": \"FAN\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01835", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 01 ). We conclude that pentoxyifylline does not inhibit dipyridamole - induced coronary hyperemia", "completion": "{\"entities\": [{\"text\": \"pentoxyifylline\", \"type\": \"Chemical\"}, {\"text\": \"dipyridamole\", \"type\": \"Chemical\"}, {\"text\": \"hyperemia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00562", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This complication will be observed even less often in the future as ticlopidine is being replaced by the newer antiplatelet agent clopidogrel", "completion": "{\"entities\": [{\"text\": \"ticlopidine\", \"type\": \"Chemical\"}, {\"text\": \"clopidogrel\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03340", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Clinical nephrotoxicity of tobramycin and gentamicin.", "completion": "{\"entities\": [{\"text\": \"nephrotoxicity\", \"type\": \"Disease\"}, {\"text\": \"tobramycin\", \"type\": \"Chemical\"}, {\"text\": \"gentamicin\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-reassigned-01570", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Total intravenous anesthesia with etomidate.", "completion": "{\"entities\": [{\"text\": \"etomidate\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01194", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These results suggest that dehydration and / or the activation of visceral afferent inputs may contribute to the elevation of plasma AVP and the upregulation of AVP gene expression in the PVN and the SON of the Li - induced diabetes insipidus", "completion": "{\"entities\": [{\"text\": \"dehydration\", \"type\": \"Disease\"}, {\"text\": \"AVP\", \"type\": \"Chemical\"}, {\"text\": \"Li\", \"type\": \"Chemical\"}, {\"text\": \"diabetes insipidus\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01640", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: OUTCOME: Following discontinuation of LEV, EEG and neuropsychological findings improved and seizure", "completion": "{\"entities\": [{\"text\": \"LEV\", \"type\": \"Chemical\"}, {\"text\": \"seizure\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01645", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: We found that cocaine dose - dependently increased anxiety - like behavior in control (Dbh +/-) mice, as measured by a decrease in open arm exploration.", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"anxiety\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04009", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: CsA, FK506 and SRL all significantly decreased the GFR.", "completion": "{\"entities\": [{\"text\": \"CsA\", \"type\": \"Chemical\"}, {\"text\": \"FK506\", \"type\": \"Chemical\"}, {\"text\": \"SRL\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01012", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After the clipping of the aneurysm the isoflurane concentration was reduced to 0.", "completion": "{\"entities\": [{\"text\": \"aneurysm\", \"type\": \"Disease\"}, {\"text\": \"isoflurane\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04789", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cocaine causes memory and learning impairments in rats: involvement of nuclear factor kappa B and oxidative stress, and prevention by topiramate.", "completion": "{\"entities\": [{\"text\": \"Cocaine\", \"type\": \"Chemical\"}, {\"text\": \"memory and learning impairments\", \"type\": \"Disease\"}, {\"text\": \"topiramate\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02141", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: When activating the (Na, K )- ATPase with its substrate ATP, no changes in Km and Vmax values were observed in NO - deficient rats.", "completion": "{\"entities\": [{\"text\": \"Na\", \"type\": \"Chemical\"}, {\"text\": \"K\", \"type\": \"Chemical\"}, {\"text\": \"ATP\", \"type\": \"Chemical\"}, {\"text\": \"NO\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00743", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Nicotine - induced nystagmus correlates with midpontine activation.", "completion": "{\"entities\": [{\"text\": \"Nicotine\", \"type\": \"Chemical\"}, {\"text\": \"nystagmus\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00763", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Adriamycin - induced autophagic cardiomyocyte death plays a pathogenic role in a rat model of heart failure.", "completion": "{\"entities\": [{\"text\": \"Adriamycin\", \"type\": \"Chemical\"}, {\"text\": \"death\", \"type\": \"Disease\"}, {\"text\": \"heart failure\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04032", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: An analysis of the 75 cases that had been adequately followed up suggested that 16, including three deaths, were probably related to treatment with the drug.", "completion": "{\"entities\": [{\"text\": \"deaths\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01354", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: When hippocampal ACh was measured during testing for handling - induced convulsions, extracellular ACh was significantly elevated (192 %) in WSP mice, but was nonsignificantly elevated (59 %) in WSR mice.", "completion": "{\"entities\": [{\"text\": \"ACh\", \"type\": \"Chemical\"}, {\"text\": \"convulsions\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04987", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We conclude that lidocaine reduces the incidence and severity of propofol injection pain in ambulatory patients whereas thiopentone", "completion": "{\"entities\": [{\"text\": \"lidocaine\", \"type\": \"Chemical\"}, {\"text\": \"propofol\", \"type\": \"Chemical\"}, {\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"thiopentone\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02303", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A 77 - y - old patient developed weakness of extremities, legs paralysis, dysarthria and tremor 1 h after ingestion of 200 mg ketoconazole for the first time in his life.", "completion": "{\"entities\": [{\"text\": \"weakness of extremities\", \"type\": \"Disease\"}, {\"text\": \"legs paralysis\", \"type\": \"Disease\"}, {\"text\": \"dysarthria\", \"type\": \"Disease\"}, {\"text\": \"tremor\", \"type\": \"Disease\"}, {\"text\": \"ketoconazole\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-03345", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In this study, 62 patients with confirmed initial normal renal function and treated with 2 to 5 mg / kg / day of gentamicin sulfate or tobramycin sulfate for a minimum of seven days were followed up prospectively for the development of aminoglycoside - related renal failure, defined as at least a one - third reduction in renal function.", "completion": "{\"entities\": [{\"text\": \"gentamicin sulfate\", \"type\": \"Chemical\"}, {\"text\": \"tobramycin sulfate\", \"type\": \"Chemical\"}, {\"text\": \"aminoglycoside\", \"type\": \"Chemical\"}, {\"text\": \"renal failure\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02545", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Eight of these 10 patients had complete loss of BAEP waveforms within 10 min.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03155", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: All the patients were examined for toxicity; 34 were examinable for response.", "completion": "{\"entities\": [{\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04378", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The goal of these studies was to use an animal model to examine the effects of prenatal protein deprivation on behaviors and receptor binding with relevance to schizophrenia.", "completion": "{\"entities\": [{\"text\": \"schizophrenia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01870", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Ten rats had arterial, central venous (CVP ), and subdural cannulae inserted under halothane anesthesia.", "completion": "{\"entities\": [{\"text\": \"halothane\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04894", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSION: The 4 - mg nicotine lozenge and 4 - mg nicotine", "completion": "{\"entities\": [{\"text\": \"nicotine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02952", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The region of cortex that represents the low frequencies was not obviously affected by the cochlear hearing loss", "completion": "{\"entities\": [{\"text\": \"hearing loss\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04961", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This study investigated propofol injection pain in patients undergoing ambulatory anaesthesia.", "completion": "{\"entities\": [{\"text\": \"propofol\", \"type\": \"Chemical\"}, {\"text\": \"pain\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04390", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Podocyte injury and focal segmental glomerulosclerosis have been related to mToR inhibition in some patients, but the pathways underlying these lesions remain hypothetic.", "completion": "{\"entities\": [{\"text\": \"glomerulosclerosis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03382", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A few minutes after administration of the drugs, they presented urticaria (patients 1 and 2) and conjunctivitis (patient 1 ). The purpose of our study was to determine the cause of the patients' reactions, the immunological mechanisms involved and whether these patients would be able to tolerate any kind of corticoid.", "completion": "{\"entities\": [{\"text\": \"urticaria\", \"type\": \"Disease\"}, {\"text\": \"conjunctivitis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-04324", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The progressive nature of mitochondrial injury", "completion": "{\"entities\": [{\"text\": \"mitochondrial injury\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02078", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We describe a case of transient neurological deficit that occurred after unilateral spinal anaesthesia with 8 mg of 1% hyperbaric bupivacaine slowly injected through a 25 - gauge pencil - point spinal needle.", "completion": "{\"entities\": [{\"text\": \"neurological deficit\", \"type\": \"Disease\"}, {\"text\": \"bupivacaine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-05827", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: aureus susceptible to oxacillin.", "completion": "{\"entities\": [{\"text\": \"oxacillin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03483", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The results indicate that rat atrial spontaneous beating is more dependent on [Na] o than on [Ca] o in a range of +/- 50% of their normal concentration.", "completion": "{\"entities\": [{\"text\": \"Na\", \"type\": \"Chemical\"}, {\"text\": \"Ca\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05127", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 32 ). Our study suggests that prophylactic lamivudine significantly decreases the incidence of HBV reactivation and overall morbidity in cancer patients during and after immunosuppressive therapy.", "completion": "{\"entities\": [{\"text\": \"lamivudine\", \"type\": \"Chemical\"}, {\"text\": \"cancer\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02441", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 (Roche Diagnostics, Penzberg, Germany ). HBV lamivudine - resistant strains were detected in 3 of 15 mono - infected chronic hepatitis B patients and 10 of 20 HBV-HIV co-infected patients.", "completion": "{\"entities\": [{\"text\": \"lamivudine\", \"type\": \"Chemical\"}, {\"text\": \"hepatitis B\", \"type\": \"Disease\"}, {\"text\": \"HBV-HIV co-infected\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03504", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The incidence of postoperative respiratory apnoea was compared between five patients receiving a continuous i.", "completion": "{\"entities\": [{\"text\": \"apnoea\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02682", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Previous clinical studies have proposed that risperidone' s pharmacologic profile may produce improved efficacy for negative psychotic symptoms and decreased propensity for extrapyramidal side effects; features shared by so - called' atypical' neuroleptics.", "completion": "{\"entities\": [{\"text\": \"risperidone\", \"type\": \"Chemical\"}, {\"text\": \"psychotic symptoms\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03157", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5% of the patients (95% confidence interval [CI ], 55.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04161", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Transient neurologic symptoms after spinal anesthesia: a lower incidence with prilocaine and bupivacaine than with lidocaine.", "completion": "{\"entities\": [{\"text\": \"Transient neurologic symptoms\", \"type\": \"Disease\"}, {\"text\": \"prilocaine\", \"type\": \"Chemical\"}, {\"text\": \"bupivacaine\", \"type\": \"Chemical\"}, {\"text\": \"lidocaine\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02256", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Finally, we examined the low dose of 150 mg / kg (50 mg / kg per day) using a similar washout period.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03792", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A placebo had no effect, but niacinamide was as effective as pyridoxine.", "completion": "{\"entities\": [{\"text\": \"niacinamide\", \"type\": \"Chemical\"}, {\"text\": \"pyridoxine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03856", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Fentanyl is a commonly used supplement that may contribute to this, although it may also improve analgesia.", "completion": "{\"entities\": [{\"text\": \"Fentanyl\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00289", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5% to evaluate the effect of aspirin on the increased cell proliferation induced by FANFT in the forestomach and bladder.", "completion": "{\"entities\": [{\"text\": \"aspirin\", \"type\": \"Chemical\"}, {\"text\": \"FANFT\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01165", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHOD: Open, case series design.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02897", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It increases the behaviour stimulation evoked by phenylephrine (given intraventricularly) in rats, evaluated in the open field test as well as the aggressiveness evoked by clonidine in mice, both these effects being mediated by an alpha1 - adrenergic receptor.", "completion": "{\"entities\": [{\"text\": \"phenylephrine\", \"type\": \"Chemical\"}, {\"text\": \"aggressiveness\", \"type\": \"Disease\"}, {\"text\": \"clonidine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-reassigned-03470", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 nmol mouse - 1, i.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04993", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: immediately before the induction of anaesthesia, to prevent arrhythmia and bradycardia following repeated doses of suxamethonium in children, was studied.", "completion": "{\"entities\": [{\"text\": \"arrhythmia\", \"type\": \"Disease\"}, {\"text\": \"bradycardia\", \"type\": \"Disease\"}, {\"text\": \"suxamethonium\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02195", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: One week later, by mistake, losartan was prescribed again and after the second dose of 50 mg, the patient developed a second episode of transient anuria lasting 10 hours.", "completion": "{\"entities\": [{\"text\": \"losartan\", \"type\": \"Chemical\"}, {\"text\": \"anuria\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01251", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These analyses suggest that the higher risk observed for the newer OC", "completion": "{\"entities\": [{\"text\": \"OC\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01516", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We report a woman with coronary artery disease who developed a markedly prolonged QT interval and torsades de pointes (TdP) after taking ketoconazole for treatment of fungal infection.", "completion": "{\"entities\": [{\"text\": \"coronary artery disease\", \"type\": \"Disease\"}, {\"text\": \"prolonged QT interval\", \"type\": \"Disease\"}, {\"text\": \"torsades de pointes\", \"type\": \"Disease\"}, {\"text\": \"TdP\", \"type\": \"Disease\"}, {\"text\": \"ketoconazole\", \"type\": \"Chemical\"}, {\"text\": \"fungal infection\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-03807", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: NRA0160 has negligible affinity for the human cloned dopamine D3 receptor (Ki = 39 nM ), rat serotonin (5-HT) 2A receptors (Ki = 180 nM) and rat alpha1 adrenoceptor (Ki = 237 nM ). NRA0160 and clozapine antagonized locomotor hyperactivity induced by methamphetamine (MAP) in mice.", "completion": "{\"entities\": [{\"text\": \"NRA0160\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}, {\"text\": \"serotonin\", \"type\": \"Chemical\"}, {\"text\": \"5-HT\", \"type\": \"Chemical\"}, {\"text\": \"clozapine\", \"type\": \"Chemical\"}, {\"text\": \"hyperactivity\", \"type\": \"Disease\"}, {\"text\": \"methamphetamine\", \"type\": \"Chemical\"}, {\"text\": \"MAP\", \"type\": \"Chemical\"}]}", "n_entities": 8}
{"ref": "bc5cdr-train-04865", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: This was a multicenter, randomized, open - label study in adult smokers with heart disease, hypertension not controlled by medication, and / or diabetes mellitus.", "completion": "{\"entities\": [{\"text\": \"heart disease\", \"type\": \"Disease\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}, {\"text\": \"diabetes mellitus\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01716", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Induction of anesthesia was followed by a decrease in MAP, HR, SV, and CO concomitant with an elevation in S (c) O (2 ). After administration of phenylephrine, MAP increased (51 +/- 12 to 81 +/- 13 mmHg; P < 0.", "completion": "{\"entities\": [{\"text\": \"a decrease in MAP, HR, SV, and CO\", \"type\": \"Disease\"}, {\"text\": \"phenylephrine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-03117", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 9 mg for untreated rats.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02495", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METH depleted DA, caused microglial activation, and increased body temperature in CX3CR1 knockout mice to the same extent and over the same time course seen in wild - type controls.", "completion": "{\"entities\": [{\"text\": \"METH\", \"type\": \"Chemical\"}, {\"text\": \"DA\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00727", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 27 in the isolated - HIT group had a significantly higher chance of developing thrombosis by day 30.", "completion": "{\"entities\": [{\"text\": \"HIT\", \"type\": \"Disease\"}, {\"text\": \"thrombosis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03313", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: In man, differences in angiotensin - converting enzyme (ACE) levels, related to ACE (I / D) genotype, are associated with renal prognosis.", "completion": "{\"entities\": [{\"text\": \"angiotensin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05073", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: FK 506 decreased eNOS activity and the levels of eNOS mRNA in the aorta (48% and 55 %, respectively ). The administration of FR 139317 (10 mg.", "completion": "{\"entities\": [{\"text\": \"FK 506\", \"type\": \"Chemical\"}, {\"text\": \"FR 139317\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01937", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These changes in the serum transaminases were associated with corresponding depletions in the cardiac GOT and GPT.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00939", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A case of genuine stress incontinence due to prazosin, a common antihypertensive drug, is presented.", "completion": "{\"entities\": [{\"text\": \"stress incontinence\", \"type\": \"Disease\"}, {\"text\": \"prazosin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02787", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Lamivudine therapy was started 3 - 7 days prior to immunosuppressive therapy in all patients.", "completion": "{\"entities\": [{\"text\": \"Lamivudine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02717", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In this study, we examined the roles of lipopolysaccharide, a pro - inflammatory and inflammatory factor, treatment in modulating the methamphetamine - induced nigrostriatal dopamine neurotoxicity.", "completion": "{\"entities\": [{\"text\": \"lipopolysaccharide\", \"type\": \"Chemical\"}, {\"text\": \"methamphetamine\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}, {\"text\": \"neurotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01587", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These observations suggest that statins may initiate an immune - mediated myopathy that persists after withdrawal of the drug and responds to immunosuppressive therapy.", "completion": "{\"entities\": [{\"text\": \"statins\", \"type\": \"Chemical\"}, {\"text\": \"myopathy\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03982", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Fetuses were delivered on GD 21 and routinely examined.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04903", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Propylthiouracil - induced perinuclear - staining antineutrophil cytoplasmic autoantibody - positive vasculitis in conjunction with pericarditis.", "completion": "{\"entities\": [{\"text\": \"Propylthiouracil\", \"type\": \"Chemical\"}, {\"text\": \"vasculitis\", \"type\": \"Disease\"}, {\"text\": \"pericarditis\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03590", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In order to increase clot stability, FS typically contain aprotinin, a natural fibrinolysis inhibitor.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03380", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pseudo - allergic reactions to corticosteroids: diagnosis and alternatives.", "completion": "{\"entities\": [{\"text\": \"allergic reactions\", \"type\": \"Disease\"}, {\"text\": \"corticosteroids\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01999", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 %) of depression, enuresis, disinhibition and aggression; and more side - effects, particularly sedation, irritability, impaired memory, weight loss and ataxia.", "completion": "{\"entities\": [{\"text\": \"depression\", \"type\": \"Disease\"}, {\"text\": \"enuresis\", \"type\": \"Disease\"}, {\"text\": \"aggression\", \"type\": \"Disease\"}, {\"text\": \"irritability\", \"type\": \"Disease\"}, {\"text\": \"impaired memory\", \"type\": \"Disease\"}, {\"text\": \"weight loss\", \"type\": \"Disease\"}, {\"text\": \"ataxia\", \"type\": \"Disease\"}]}", "n_entities": 7}
{"ref": "bc5cdr-train-02499", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We conclude from these studies that CX3CR1 signaling does not modulate METH neurotoxicity or microglial activation.", "completion": "{\"entities\": [{\"text\": \"METH\", \"type\": \"Chemical\"}, {\"text\": \"neurotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01771", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Total cumulative doses were 36 or 60 g / m2 of ifosfamide (six or 10 cycles of ifosfamide, vincristine, and dactinomycin [IVA ]). of them had received cisplatin chemotherapy.", "completion": "{\"entities\": [{\"text\": \"ifosfamide\", \"type\": \"Chemical\"}, {\"text\": \"ifosfamide, vincristine, and dactinomycin\", \"type\": \"Chemical\"}, {\"text\": \"IVA\", \"type\": \"Chemical\"}, {\"text\": \"cisplatin\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00233", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The most striking effect was sedation which increased with the dose, 2 mg producing deep sleep although the subjects could still be aroused.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04046", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Combined effects of prolonged prostaglandin E1 - induced hypotension and haemodilution on human hepatic function.", "completion": "{\"entities\": [{\"text\": \"prostaglandin E1\", \"type\": \"Chemical\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}, {\"text\": \"haemodilution\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01619", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Immunohistochemical studies showed that administration of terbutaline on PN 2 to 5 produced a robust increase in microglial activation on PN 30 in the cerebral cortex, as well as in cerebellar and cerebrocortical white matter.", "completion": "{\"entities\": [{\"text\": \"terbutaline\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01318", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: We conducted a prospective, randomized, double - blind study in the emergency department of a central - city teaching hospital.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04450", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Increased production of FRs may cause mtDNA damage leading to decreased activities of oxidative phosphorylation complexes containing mtDNA - encoded subunits.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04177", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Times to ambulate and to void were similar after lidocaine and prilocaine (150 vs.", "completion": "{\"entities\": [{\"text\": \"lidocaine\", \"type\": \"Chemical\"}, {\"text\": \"prilocaine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00041", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Fusidic acid is an antibiotic with T - cell specific immunosuppressive effects similar to those of cyclosporin.", "completion": "{\"entities\": [{\"text\": \"cyclosporin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03480", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Dose - dependent bradycardia induced by verapamil was potentiated by LNa, LCa, and HCa.", "completion": "{\"entities\": [{\"text\": \"bradycardia\", \"type\": \"Disease\"}, {\"text\": \"verapamil\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02776", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Patency of the airway and independent respiration were maintained in all of the patients.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02708", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: SUMMARY: The patient' s medical and dental histories along with radiographic and clinical findings lead to a diagnosis of\" meth mouth .\" Although three different dental treatment modalities (either conventional or implant - supported) have been offered to the patient since August 2007, the patient has yet to initiate any treatment.", "completion": "{\"entities\": [{\"text\": \"meth mouth\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01705", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: o .). Importantly, both classical (haloperidol) and atypical (olanzapine, clozapine and aripiprazole) antipsychotics were effective in all these models of hyperactivity.", "completion": "{\"entities\": [{\"text\": \"haloperidol\", \"type\": \"Chemical\"}, {\"text\": \"olanzapine\", \"type\": \"Chemical\"}, {\"text\": \"clozapine\", \"type\": \"Chemical\"}, {\"text\": \"aripiprazole\", \"type\": \"Chemical\"}, {\"text\": \"hyperactivity\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-02641", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The other proteins showed few changes, which were limited to diseased areas.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02365", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Medical records were studied retrospectively to evaluate whether warfarin and warfarin - drug interactions could have caused the cerebral haemorrhage.", "completion": "{\"entities\": [{\"text\": \"warfarin\", \"type\": \"Chemical\"}, {\"text\": \"cerebral haemorrhage\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01358", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Dexamethasone is frequently administered to the developing fetus to accelerate pulmonary development.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01522", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The present study was aimed at investigating the effects of Daucus carota seeds on cognitive functions, total serum cholesterol levels and brain cholinesterase activity in mice.", "completion": "{\"entities\": [{\"text\": \"cholesterol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04698", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: She subsequently died some 5 weeks after the commencement of her drug therapy.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02187", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We report a case of a living donor renal transplant recipient who developed cyclosporine - induced TMA that responded to the withdrawal of cyclosporine in conjunction with plasmapheresis and fresh frozen plasma replacement therapy.", "completion": "{\"entities\": [{\"text\": \"cyclosporine\", \"type\": \"Chemical\"}, {\"text\": \"TMA\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03289", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The animal model used to produce infarction implies artery ligation but chemical induction can be easily obtained with isoproterenol.", "completion": "{\"entities\": [{\"text\": \"infarction\", \"type\": \"Disease\"}, {\"text\": \"isoproterenol\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01762", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Depression and sexual dysfunction have been related to side effects of topical beta - blockers.", "completion": "{\"entities\": [{\"text\": \"Depression\", \"type\": \"Disease\"}, {\"text\": \"sexual dysfunction\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04059", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Recent preclinical and clinical data from promising lines of research focus on the differential role of presynaptic versus postsynaptic mechanisms, dopamine receptor subtypes, ionotropic and metabotropic glutamate receptors, and non - dopaminergic neurotransmitter systems in the pathophysiology of levodopa - induced dyskinesias", "completion": "{\"entities\": [{\"text\": \"dopamine\", \"type\": \"Chemical\"}, {\"text\": \"glutamate\", \"type\": \"Chemical\"}, {\"text\": \"levodopa\", \"type\": \"Chemical\"}, {\"text\": \"dyskinesias\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02306", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Laboratory evaluations, including head CT scan, were normal.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04809", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: p .) in the mouse passive - avoidance test.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02813", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 7 %). The multivariate analysis showed that severe MR, MP (EF < 45 %) and high doses of MZ (> 5mg) were associated with events (p < 0.", "completion": "{\"entities\": [{\"text\": \"MR\", \"type\": \"Disease\"}, {\"text\": \"MP\", \"type\": \"Disease\"}, {\"text\": \"MZ\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00203", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Nevertheless, there occurs some real tolerance to this effect.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02373", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Almost half of the cases was related to a warfarin - drug interaction.", "completion": "{\"entities\": [{\"text\": \"warfarin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00350", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: As the relative increase in PRL secretion expressed as a percentage of the mean did not significantly differ between the night and day time studies (46 +/- 19% vs 34 +/- 10 %), it can be concluded that the observed sleep disturbance did not interfere with the drug action per se.", "completion": "{\"entities\": [{\"text\": \"sleep disturbance\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01100", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A detailed clinical history, together with skin tests, RAST (radioallergosorbent test ), and controlled challenge tests, was used to establish whether patients allergic to beta-lactam antibiotics had selective immediate allergic responses to amoxicillin (AX) or were cross - reacting with other penicillin derivatives.", "completion": "{\"entities\": [{\"text\": \"allergic\", \"type\": \"Disease\"}, {\"text\": \"beta-lactam\", \"type\": \"Chemical\"}, {\"text\": \"amoxicillin\", \"type\": \"Chemical\"}, {\"text\": \"AX\", \"type\": \"Chemical\"}, {\"text\": \"penicillin\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-02771", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A board - certified emergency physician skilled in airway management supervised administration of the anesthetic, and the patients were monitored by a registered nurse.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00082", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Chloroacetaldehyde and its contribution to urotoxicity during treatment with cyclophosphamide or ifosfamide.", "completion": "{\"entities\": [{\"text\": \"Chloroacetaldehyde\", \"type\": \"Chemical\"}, {\"text\": \"cyclophosphamide\", \"type\": \"Chemical\"}, {\"text\": \"ifosfamide\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00690", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Data on use of BZDs / RDs before admission, current medications and discharge diagnoses were collected from medical records.", "completion": "{\"entities\": [{\"text\": \"BZDs\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03913", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This drug caused biventricular dysfunction, due to its negative inotropic effect, and hypotension", "completion": "{\"entities\": [{\"text\": \"biventricular dysfunction\", \"type\": \"Disease\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03983", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Comprehensive clinical and developmental measurements were done.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03221", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We studied three calcium channel blockers of different structure, nifedipine, diltiazem, and verapamil, along with the new agent.", "completion": "{\"entities\": [{\"text\": \"calcium\", \"type\": \"Chemical\"}, {\"text\": \"nifedipine\", \"type\": \"Chemical\"}, {\"text\": \"diltiazem\", \"type\": \"Chemical\"}, {\"text\": \"verapamil\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-reassigned-01920", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Acute renal failure due to rifampicin.", "completion": "{\"entities\": [{\"text\": \"Acute renal failure\", \"type\": \"Disease\"}, {\"text\": \"rifampicin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02140", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After 4 - week administration of L-NAME, the systolic blood pressure (SBP) increased by 36 %. Two weeks after terminating the treatment, the SBP recovered to control value.", "completion": "{\"entities\": [{\"text\": \"L-NAME\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00014", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: to 36 adult males at six rates: 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01458", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: OBJECTIVE: To examine the effect of raloxifene on major adverse events that occur with postmenopausal estrogen therapy or tamoxifen.", "completion": "{\"entities\": [{\"text\": \"raloxifene\", \"type\": \"Chemical\"}, {\"text\": \"estrogen\", \"type\": \"Chemical\"}, {\"text\": \"tamoxifen\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02517", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Compared to controls, aortic regurgitation (OR: 3.", "completion": "{\"entities\": [{\"text\": \"aortic regurgitation\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04598", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Echocardiographic data from the experimental group of 21 patients (mean age 16 +/- 5 years) treated from 1.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02447", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It remains to be seen whether such pre - existing antiviral mutations could result in widespread emergence of HBV resistant strains when lamivudine - containing highly active antiretroviral (ARV) treatment (HAART) regimens become widely applied in South Africa, as this is likely to have potential implications in the management of HBV-HIV co-infected", "completion": "{\"entities\": [{\"text\": \"lamivudine\", \"type\": \"Chemical\"}, {\"text\": \"HBV-HIV co-infected\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02119", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Tamoxifen (TAM ), the antiestrogenic drug most widely prescribed in the chemotherapy of breast cancer, induces changes in normal discoid shape of erythrocytes and hemolytic anemia.", "completion": "{\"entities\": [{\"text\": \"Tamoxifen\", \"type\": \"Chemical\"}, {\"text\": \"TAM\", \"type\": \"Chemical\"}, {\"text\": \"breast cancer\", \"type\": \"Disease\"}, {\"text\": \"hemolytic anemia\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02824", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The local anesthetic - induced mortality was significantly increased by the three different calcium channel blockers.", "completion": "{\"entities\": [{\"text\": \"calcium\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00919", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Multiple daily doses of lithium were associated with higher urine volumes.", "completion": "{\"entities\": [{\"text\": \"lithium\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04523", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Anencephaly has been suggested to develop from exencephaly; however, there is little direct experimental evidence to support this, and the mechanism of transformation remains unclear.", "completion": "{\"entities\": [{\"text\": \"Anencephaly\", \"type\": \"Disease\"}, {\"text\": \"exencephaly\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00744", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The pathomechanism of nicotine - induced nystagmus (NIN) is unknown.", "completion": "{\"entities\": [{\"text\": \"nicotine\", \"type\": \"Chemical\"}, {\"text\": \"nystagmus\", \"type\": \"Disease\"}, {\"text\": \"NIN\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04463", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Three of these cases were from the 25 transplantations performed at King Fahad National Guard Hospital, while the other 2 transplantations had been performed abroad and were referred to us for follow - up.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-reassigned-05362", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Carbimazole induced ANCA positive vasculitis.", "completion": "{\"entities\": [{\"text\": \"Carbimazole\", \"type\": \"Chemical\"}, {\"text\": \"ANCA positive vasculitis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03562", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Treatment strategies depend on the correct diagnosis of the pain.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01196", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The present report describes a case of cardiac arrest and subsequent death as a result of hyperkalaemia following the use of suxamethonium in a 23 - year - old Malawian woman.", "completion": "{\"entities\": [{\"text\": \"cardiac arrest\", \"type\": \"Disease\"}, {\"text\": \"death\", \"type\": \"Disease\"}, {\"text\": \"hyperkalaemia\", \"type\": \"Disease\"}, {\"text\": \"suxamethonium\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02815", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Effects of calcium channel blockers on bupivacaine - induced toxicity.", "completion": "{\"entities\": [{\"text\": \"calcium\", \"type\": \"Chemical\"}, {\"text\": \"bupivacaine\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00279", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Both drugs impaired immediate free recall but the decrease was greater for diazepam than propranolol.", "completion": "{\"entities\": [{\"text\": \"impaired immediate free recall\", \"type\": \"Disease\"}, {\"text\": \"diazepam\", \"type\": \"Chemical\"}, {\"text\": \"propranolol\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01030", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A case of veno-occlusive disease of the liver with fatal outcome after dacarbazine (DTIC) therapy for melanoma is reported.", "completion": "{\"entities\": [{\"text\": \"veno-occlusive disease of the liver\", \"type\": \"Disease\"}, {\"text\": \"dacarbazine\", \"type\": \"Chemical\"}, {\"text\": \"DTIC\", \"type\": \"Chemical\"}, {\"text\": \"melanoma\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-reassigned-01915", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 4 mmHg (P less than 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01962", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cimetidine clearance decreased with age.", "completion": "{\"entities\": [{\"text\": \"Cimetidine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05146", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Injections areas were assessed for the presence of bruising at 48 and 72 hours after each injection.", "completion": "{\"entities\": [{\"text\": \"bruising\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00199", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: p .) was used in order to block the dopaminergic activation and to estimate the real degree of the tolerance to the rigidity without any dopaminergic interference.", "completion": "{\"entities\": [{\"text\": \"rigidity\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02896", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: TRI given repeatedly to rats increases the locomotor hyperactivity induced by d-amphetamine, quinpirole and (+)- 7 - hydroxy - dipropyloaminotetralin (dopamine D2 and D3 effects ). The stereotypies induced by d-amphetamine or apomorphine are not potentiated by TRI.", "completion": "{\"entities\": [{\"text\": \"TRI\", \"type\": \"Chemical\"}, {\"text\": \"hyperactivity\", \"type\": \"Disease\"}, {\"text\": \"d-amphetamine\", \"type\": \"Chemical\"}, {\"text\": \"quinpirole\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}, {\"text\": \"apomorphine\", \"type\": \"Chemical\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-01264", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the present paper the authors describe 2 female patients who developed incontinence secondary to the selective serotonin reuptake inhibitors paroxetine and sertraline, as well as a third who developed this side effect on venlafaxine.", "completion": "{\"entities\": [{\"text\": \"incontinence\", \"type\": \"Disease\"}, {\"text\": \"serotonin\", \"type\": \"Chemical\"}, {\"text\": \"paroxetine\", \"type\": \"Chemical\"}, {\"text\": \"sertraline\", \"type\": \"Chemical\"}, {\"text\": \"venlafaxine\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-02973", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Salbutamol significantly increased tremor severity in patients in a dose - dependent way.", "completion": "{\"entities\": [{\"text\": \"Salbutamol\", \"type\": \"Chemical\"}, {\"text\": \"tremor\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04929", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These episodes reversed after the administration of diazepam 1 mg intravenously.", "completion": "{\"entities\": [{\"text\": \"diazepam\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02694", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: She underwent liver transplantation with an uneventful postoperative course.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04977", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05) than in Group C (100 %) but not different from Group T (90 %). The VAS scores for recall of pain in the recovery room were correlated with the VAS scores during induction (r = 0.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04039", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In contrast, the results of histological examination of the liver often showed evidence of cholestasis.", "completion": "{\"entities\": [{\"text\": \"cholestasis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03888", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: v .) and thioperamide (THP )(15 mg / kg i.", "completion": "{\"entities\": [{\"text\": \"thioperamide\", \"type\": \"Chemical\"}, {\"text\": \"THP\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05059", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pretreatment of mice with alpha-methyltyrosine (20 mg / kg i.", "completion": "{\"entities\": [{\"text\": \"alpha-methyltyrosine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01072", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: During the study, vitamin B12 and folate levels were significantly higher in group II patients; however, no differences in hemoglobin, hematocrit, mean corpuscular volume, and white - cell, neutrophil and platelet counts were observed between groups at 3, 6, 9 and 12 months.", "completion": "{\"entities\": [{\"text\": \"vitamin B12\", \"type\": \"Chemical\"}, {\"text\": \"folate\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04191", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After the ingestion of 26 venlafaxine 50 - mg tablets, the patient experienced a witnessed generalized seizure.", "completion": "{\"entities\": [{\"text\": \"venlafaxine\", \"type\": \"Chemical\"}, {\"text\": \"seizure\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05130", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Rg1, as a ginsenoside extracted from Panax ginseng, could ameliorate spatial learning impairment.", "completion": "{\"entities\": [{\"text\": \"Rg1\", \"type\": \"Chemical\"}, {\"text\": \"ginsenoside\", \"type\": \"Chemical\"}, {\"text\": \"learning impairment\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00122", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Folate depletion has often been a problem in chronic antiepileptic drug (AED) therapy.", "completion": "{\"entities\": [{\"text\": \"Folate\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03379", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In conclusion, this study provides new insights into the protein changes occurring in LID", "completion": "{\"entities\": [{\"text\": \"LID\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01695", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The patient' s ophthalmological symptoms improved rapidly 3 weeks after discontinuation of pegylated IFN alpha-2b and ribavirin.", "completion": "{\"entities\": [{\"text\": \"pegylated IFN alpha-2b\", \"type\": \"Chemical\"}, {\"text\": \"ribavirin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00813", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: ATT - ALF patients were younger (32.", "completion": "{\"entities\": [{\"text\": \"ALF\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04229", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: of the animals that received bupivacaine, normal saline, or normal saline titrated to a pH 3.", "completion": "{\"entities\": [{\"text\": \"bupivacaine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04328", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 02) with intravenous nitroglycerin.", "completion": "{\"entities\": [{\"text\": \"nitroglycerin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00167", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The pentose phosphate shunt activity of the non - dapsone - exposed AE RBCs was decreased compared to normal RBCs.", "completion": "{\"entities\": [{\"text\": \"pentose phosphate\", \"type\": \"Chemical\"}, {\"text\": \"dapsone\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03036", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Anti - epileptic drugs - induced de novo absence seizures.", "completion": "{\"entities\": [{\"text\": \"epileptic\", \"type\": \"Disease\"}, {\"text\": \"absence seizures\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03507", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 6 mg) and five patients receiving a continuous extradural infusion of 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01917", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These data indicate that a critical percentage of NTE inhibition in brain and spinal cord sampled shortly after Mipafox exposure can predict neuropathic damage", "completion": "{\"entities\": [{\"text\": \"Mipafox\", \"type\": \"Chemical\"}, {\"text\": \"neuropathic damage\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00608", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Taken together, the present study demonstrates that the central injection of U-II at doses of 1 - 10, 000 ng / mouse induces anxiogenic - and depressant - like effects in mouse.", "completion": "{\"entities\": [{\"text\": \"U-II\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04937", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Endocrine screening in 1, 022 men with erectile dysfunction: clinical significance and cost - effective strategy.", "completion": "{\"entities\": [{\"text\": \"erectile dysfunction\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01090", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: OBJECTIVE: To report a case of erythema multiforme and hypersensitivity myocarditis caused by ampicillin.", "completion": "{\"entities\": [{\"text\": \"erythema multiforme\", \"type\": \"Disease\"}, {\"text\": \"hypersensitivity myocarditis\", \"type\": \"Disease\"}, {\"text\": \"ampicillin\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04411", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the present study, we have investigated the molecular mechanisms by which female hormones influence cholesterol metabolism in macrophages in response to the HIV protease inhibitor ritonavir.", "completion": "{\"entities\": [{\"text\": \"cholesterol\", \"type\": \"Chemical\"}, {\"text\": \"ritonavir\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03097", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Lesions reduced the extent of immunohistological staining for choline acetyltransferase in the interpeduncular nucleus (p < 0.", "completion": "{\"entities\": [{\"text\": \"choline\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03236", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The convulsive threshold (mean +/- SD) was 41.", "completion": "{\"entities\": [{\"text\": \"convulsive\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03454", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Since the introduction of angiotensin converting enzyme (ACE) inhibitors into the adjunctive treatment of patients with congestive heart failure, cases of severe hypotension, especially on the first day of treatment, have occasionally been reported.", "completion": "{\"entities\": [{\"text\": \"angiotensin converting enzyme (ACE) inhibitors\", \"type\": \"Chemical\"}, {\"text\": \"congestive heart failure\", \"type\": \"Disease\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00047", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: and the treatment was planned to last 8 weeks.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-reassigned-00888", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The diagnosis of metronidazole toxicity", "completion": "{\"entities\": [{\"text\": \"metronidazole\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04077", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Administration of salvianolic acid A for a period of 8 days significantly attenuated isoproterenol - induced cardiac dysfunction and myocardial injury and improved mitochondrial respiratory function.", "completion": "{\"entities\": [{\"text\": \"salvianolic acid A\", \"type\": \"Chemical\"}, {\"text\": \"isoproterenol\", \"type\": \"Chemical\"}, {\"text\": \"cardiac dysfunction\", \"type\": \"Disease\"}, {\"text\": \"myocardial injury\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02383", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Postoperatively, all patients were assessed for symptoms of nausea, vomiting, and headache.", "completion": "{\"entities\": [{\"text\": \"nausea, vomiting\", \"type\": \"Disease\"}, {\"text\": \"headache\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00487", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: anticonvulsants ), and temperament of the patient, assessed during a normothymic period using the hyperthymia component of the Semi - structured Affective Temperament Interview.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-05015", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Flestolol produced a dose - dependent attenuation of isoproterenol - induced tachycardia.", "completion": "{\"entities\": [{\"text\": \"Flestolol\", \"type\": \"Chemical\"}, {\"text\": \"isoproterenol\", \"type\": \"Chemical\"}, {\"text\": \"tachycardia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02385", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Sixty percent in Group A developed postoperative emetic symptoms, headache, or both; 1 patient in Group B developed symptoms.", "completion": "{\"entities\": [{\"text\": \"postoperative emetic symptoms\", \"type\": \"Disease\"}, {\"text\": \"headache\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01106", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 %) cases of immediate AX allergy with good tolerance of PG.", "completion": "{\"entities\": [{\"text\": \"AX\", \"type\": \"Chemical\"}, {\"text\": \"allergy\", \"type\": \"Disease\"}, {\"text\": \"PG\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02684", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: There was no significant difference between occupancy levels obtained with haloperidol or risperidone.", "completion": "{\"entities\": [{\"text\": \"haloperidol\", \"type\": \"Chemical\"}, {\"text\": \"risperidone\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02529", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Severity of regurgitation was not correlated with pergolide cumulative dose.", "completion": "{\"entities\": [{\"text\": \"pergolide\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01772", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Ages ranged from 4 months to 17 years; 58 patients were males and 42 females.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04212", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: All six patients had supersaturated bile (mean (SEM) cholesterol saturation index of 1.", "completion": "{\"entities\": [{\"text\": \"cholesterol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04304", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BE - Injected rats that did not have seizures had significantly more locomotor activity than cocaine - injected animals without seizures.", "completion": "{\"entities\": [{\"text\": \"BE\", \"type\": \"Chemical\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04228", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 )(N = 20 ), or normal saline (N = 10 ). Of the 20 animals that received subarachnoid injection of 2-chloroprocaine-CE seven (35 %) developed hind - limb paralysis.", "completion": "{\"entities\": [{\"text\": \"2-chloroprocaine-CE\", \"type\": \"Chemical\"}, {\"text\": \"paralysis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02783", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: From June 2004 to October 2006, 11 HBs Ag positive patients with rheumatologic diseases, who were on both immunosuppressive and prophylactic lamivudine therapies, were retrospectively assessed.", "completion": "{\"entities\": [{\"text\": \"HBs Ag\", \"type\": \"Chemical\"}, {\"text\": \"rheumatologic diseases\", \"type\": \"Disease\"}, {\"text\": \"lamivudine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02657", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These findings show that the brain - dissociated state induced by pentobarbital", "completion": "{\"entities\": [{\"text\": \"pentobarbital\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03690", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The remaining patient in the series developed fulminant hepatitis when the drug was accidentally recommenced 1 year after a prior episode of methyldopa - induced hepatitis.", "completion": "{\"entities\": [{\"text\": \"fulminant hepatitis\", \"type\": \"Disease\"}, {\"text\": \"hepatitis\", \"type\": \"Disease\"}, {\"text\": \"methyldopa\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02214", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Additionally, this may have been the first report on AMI - induced apoptotic death in the lung tissue.", "completion": "{\"entities\": [{\"text\": \"AMI\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03535", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: v ., weekly for up to 8 weeks for a total cumulative dose of 12 mg / kg BW.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02139", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: To assess the molecular basis of disturbances in transmembraneous transport of Na +, we studied the response of cardiac (Na, K )- ATPase to NO - deficient hypertension induced in rats by NO - synthase inhibition with 40 mg / kg / day N(G)-nitro-L-arginine methyl ester (L-NAME) for 4 four weeks.", "completion": "{\"entities\": [{\"text\": \"Na\", \"type\": \"Chemical\"}, {\"text\": \"K\", \"type\": \"Chemical\"}, {\"text\": \"NO\", \"type\": \"Chemical\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}, {\"text\": \"N(G)-nitro-L-arginine methyl ester\", \"type\": \"Chemical\"}, {\"text\": \"L-NAME\", \"type\": \"Chemical\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-01881", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Obviously, there is a need for effective chemotherapy.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03683", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Twelve patients with liver disease related to methyldopa were seen between 1967 and 1977.", "completion": "{\"entities\": [{\"text\": \"liver disease\", \"type\": \"Disease\"}, {\"text\": \"methyldopa\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00650", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 2 to 12) after conversion (P = 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01044", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A case of a busulfan - induced hemorrhage cystitis is reported.", "completion": "{\"entities\": [{\"text\": \"busulfan\", \"type\": \"Chemical\"}, {\"text\": \"hemorrhage cystitis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03163", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 4 %). After 154 courses of therapy, the median dose intensity was 131 mg / m (2) for paclitaxel (97.", "completion": "{\"entities\": [{\"text\": \"paclitaxel\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02039", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Lesions of the capillary included necrosis of endothelial cells.", "completion": "{\"entities\": [{\"text\": \"necrosis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02007", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In an attempt to determine whether penile pain associated with intracorporeal injections could be due to the acidity of the medication, we performed a randomized study comparing the incidence of penile pain following intracorporeal injections with or without the addition of sodium bicarbonate to the intracorporeal medications.", "completion": "{\"entities\": [{\"text\": \"penile pain\", \"type\": \"Disease\"}, {\"text\": \"sodium bicarbonate\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02042", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pressure on the vessel wall was produced by enlarged perivascular astrocytic processes.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01388", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This is the first case report of pseudoacromegaly as a side effect of minoxidil", "completion": "{\"entities\": [{\"text\": \"pseudoacromegaly\", \"type\": \"Disease\"}, {\"text\": \"minoxidil\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02683", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: To determine if routine risperidone treatment is associated with a unique degree of D2 receptor occupancy and pattern of clinical effects, we used [123I] IBZM SPECT to determine D2 occupancy in subjects treated with routine clinical doses of risperidone (n = 12) or haloperidol (n = 7 ). Both risperidone and haloperidol produced D2 occupancy levels between approximately 60 and 90% at standard clinical doses.", "completion": "{\"entities\": [{\"text\": \"risperidone\", \"type\": \"Chemical\"}, {\"text\": \"haloperidol\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05024", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Six weeks after clipping of one renal artery, hypertensive rats (178 +/- 4 mm Hg) were randomly assigned to three groups: untreated hypertensive controls (n = 8 ), enalapril - treated (n = 8 ), or nitrendipine - treated (n = 10 ). Sham - operated rats served as normotensive controls (128 +/- 3 mm Hg, n = 8 ). After 6 weeks of treatment, renal hemodynamics (glomerular filtration rate and renal plasma flow) were measured in the anesthetized rats.", "completion": "{\"entities\": [{\"text\": \"hypertensive\", \"type\": \"Disease\"}, {\"text\": \"enalapril\", \"type\": \"Chemical\"}, {\"text\": \"nitrendipine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00510", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: No changes were found in other cohorts.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03310", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A starting dose of 1 mg / day with gradual, upward dose titration is recommended.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01438", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The present study investigated whether this effect of estrogen involves interaction with alpha2 - and / or I1 - receptors.", "completion": "{\"entities\": [{\"text\": \"estrogen\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00607", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Whatever was the dose, the central administration of U-II had no effect on body temperature, nociception, apomorphine - induced penile erection and climbing behavior, and stress - induced plasma corticosterone level.", "completion": "{\"entities\": [{\"text\": \"U-II\", \"type\": \"Chemical\"}, {\"text\": \"apomorphine\", \"type\": \"Chemical\"}, {\"text\": \"penile erection\", \"type\": \"Disease\"}, {\"text\": \"corticosterone\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01667", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Between July 2001 and April 2004, 24 patients with relapsed / refractory indolent lymphomas received thalidomide 200 mg daily with escalation by 100 mg daily every 1 - 2 weeks as tolerated, up to a maximum of 800 mg daily.", "completion": "{\"entities\": [{\"text\": \"lymphomas\", \"type\": \"Disease\"}, {\"text\": \"thalidomide\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03727", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Adriamycinol, doxorubicin, adriamycinone, and tetrahydropyranyladriamycinol were the metabolites detected in plasma and the amount of doxorubicin was less than or equal to 10% of the total metabolites.", "completion": "{\"entities\": [{\"text\": \"Adriamycinol\", \"type\": \"Chemical\"}, {\"text\": \"doxorubicin\", \"type\": \"Chemical\"}, {\"text\": \"adriamycinone\", \"type\": \"Chemical\"}, {\"text\": \"tetrahydropyranyladriamycinol\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04364", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Testosterone - dependent hypertension and upregulation of intrarenal angiotensinogen in Dahl salt - sensitive rats.", "completion": "{\"entities\": [{\"text\": \"Testosterone\", \"type\": \"Chemical\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}, {\"text\": \"salt\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02115", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Introduction of the DSM - IV diagnosis of CIMD did not substantially affect rates of the other depressive disorders.", "completion": "{\"entities\": [{\"text\": \"CIMD\", \"type\": \"Disease\"}, {\"text\": \"depressive disorders\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03647", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 6 ), coarctation of the aorta (AOR = 2.", "completion": "{\"entities\": [{\"text\": \"coarctation of the aorta\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03840", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: While there is no single correct starting dose for levodopa therapy, many individuals can be started on either the 25 / 100 or controlled - release formula, following the general rule not to attempt to titrate carbidopa - levodopa to the point of\" normality ,\" which can lead to toxicity.", "completion": "{\"entities\": [{\"text\": \"levodopa\", \"type\": \"Chemical\"}, {\"text\": \"carbidopa\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01018", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Oral diphenhydramine and prednisone were ineffective in preventing the recurrence of the allergic reaction", "completion": "{\"entities\": [{\"text\": \"diphenhydramine\", \"type\": \"Chemical\"}, {\"text\": \"prednisone\", \"type\": \"Chemical\"}, {\"text\": \"allergic reaction\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02393", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 2 micromol / L) over baseline.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03013", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Such patients should be under close follow - up, preferably with periodic ultrasound examination of the liver.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01629", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The symptoms occurred around 2 weeks after starting clozapine in an inpatient setting.", "completion": "{\"entities\": [{\"text\": \"clozapine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03835", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pneumonitis, bilateral pleural effusions, echocardiographic evidence of cardiac tamponade, and positive autoantibodies developed in a 43 - year - old man, who was receiving long - term sulfasalazine therapy for chronic ulcerative colitis.", "completion": "{\"entities\": [{\"text\": \"Pneumonitis\", \"type\": \"Disease\"}, {\"text\": \"pleural effusions\", \"type\": \"Disease\"}, {\"text\": \"cardiac tamponade\", \"type\": \"Disease\"}, {\"text\": \"sulfasalazine\", \"type\": \"Chemical\"}, {\"text\": \"ulcerative colitis\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-04079", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The results of our study suggest that salvianolic acid A possessing antioxidant activity has a significant protective effect against isoproterenol - induced myocardial infarction", "completion": "{\"entities\": [{\"text\": \"salvianolic acid A\", \"type\": \"Chemical\"}, {\"text\": \"isoproterenol\", \"type\": \"Chemical\"}, {\"text\": \"myocardial infarction\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-05120", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: They were followed up during and for 8 weeks after CT.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00262", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Peripheral neuropathy due to nutritional deficiency of thiamine and riboflavin was common (10.", "completion": "{\"entities\": [{\"text\": \"Peripheral neuropathy\", \"type\": \"Disease\"}, {\"text\": \"nutritional deficiency\", \"type\": \"Disease\"}, {\"text\": \"thiamine\", \"type\": \"Chemical\"}, {\"text\": \"riboflavin\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01802", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Twenty patients were asked to quantify the severity of pain after receiving standard lidocaine in one femoral area and buffered lidocaine in the opposite femoral area.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"lidocaine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04308", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Here its ability to antagonize the prolonged depletion of dopamine in the striatum by amphetamine in iprindole - treated rats is reported.", "completion": "{\"entities\": [{\"text\": \"dopamine\", \"type\": \"Chemical\"}, {\"text\": \"amphetamine\", \"type\": \"Chemical\"}, {\"text\": \"iprindole\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-reassigned-02147", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Phenytoin induced fatal hepatic injury.", "completion": "{\"entities\": [{\"text\": \"Phenytoin\", \"type\": \"Chemical\"}, {\"text\": \"hepatic injury\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03801", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 7 receptors, with Ki values of 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03210", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The sudden onset of respiratory distress, rash, and a history of a new medicine led the two paramedics on the scene to administer subcutaneous epinephrine.", "completion": "{\"entities\": [{\"text\": \"respiratory distress\", \"type\": \"Disease\"}, {\"text\": \"rash\", \"type\": \"Disease\"}, {\"text\": \"epinephrine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04473", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A 35 - year - old woman whose cervix uteri was inadvertently injected with 8 mg of epinephrine developed myocardial stunning that was characterized by severe hemodynamic compromise, profound, albeit transient, left ventricular systolic and diastolic dysfunction, and only modestly elevated biochemical markers of myocardial necrosis", "completion": "{\"entities\": [{\"text\": \"epinephrine\", \"type\": \"Chemical\"}, {\"text\": \"myocardial stunning\", \"type\": \"Disease\"}, {\"text\": \"left ventricular systolic and diastolic dysfunction\", \"type\": \"Disease\"}, {\"text\": \"myocardial necrosis\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01847", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Tolerance and antiviral effect of ribavirin was studied in 6 patients with Argentine hemorrhagic fever (AHF) of more than 8 days of evolution.", "completion": "{\"entities\": [{\"text\": \"ribavirin\", \"type\": \"Chemical\"}, {\"text\": \"Argentine hemorrhagic fever\", \"type\": \"Disease\"}, {\"text\": \"AHF\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-05128", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Further studies are needed to determine the most appropriate nucleoside or nucleotide", "completion": "{\"entities\": [{\"text\": \"nucleoside\", \"type\": \"Chemical\"}, {\"text\": \"nucleotide\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00594", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Angiography and intracoronary ultrasound demonstrated lack of contact between stent and vessel wall in a 15 - mm long segment with maximal aneurysm", "completion": "{\"entities\": [{\"text\": \"aneurysm\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04092", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Admission laboratory tests were as follows: alanine aminotransferase, 67 U / L (reference range, 10 - 37 U / L ); aspartate aminotransferase, 98 U / L (10 - 40 U / L ); alkaline phosphatase, 513 U / L (0 - 270 U / L ); gamma - glutamyltransferase, 32 U / L (7 - 49 U / L ); amylase, 46 U / L (0 - 220 U / L ); total bilirubin, 20.", "completion": "{\"entities\": [{\"text\": \"alanine\", \"type\": \"Chemical\"}, {\"text\": \"aspartate\", \"type\": \"Chemical\"}, {\"text\": \"bilirubin\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04528", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5, and re - observed the same embryos at E18.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04014", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 02 ). The FK506 plus SRL combination showed only a marginally higher degree of fibrosis as compared with controls (P = 0.", "completion": "{\"entities\": [{\"text\": \"FK506\", \"type\": \"Chemical\"}, {\"text\": \"SRL\", \"type\": \"Chemical\"}, {\"text\": \"fibrosis\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00008", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Intravenous administration of a single 50 - mg bolus of lidocaine in a 67 - year - old man resulted in profound depression of the activity of the sinoatrial and atrioventricular nodal pacemakers.", "completion": "{\"entities\": [{\"text\": \"lidocaine\", \"type\": \"Chemical\"}, {\"text\": \"depression\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05107", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 7) for the placebo group (P = 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01277", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: We found PTCR in 14 of 15 cases of TG, in 7 transplant biopsy specimens without TG, and in 13 of 143 native kidney biopsy specimens.", "completion": "{\"entities\": [{\"text\": \"TG\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03085", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The most common toxicities encountered were transient serum transaminase and bilirubin elevations, neutropenia, and mucositis.", "completion": "{\"entities\": [{\"text\": \"toxicities\", \"type\": \"Disease\"}, {\"text\": \"bilirubin\", \"type\": \"Chemical\"}, {\"text\": \"neutropenia\", \"type\": \"Disease\"}, {\"text\": \"mucositis\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01209", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Postoperatively, the patient refused DC cardioversion and was treated medically.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01972", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Development of clear cell adenocarcinoma in DES - exposed offspring under observation.", "completion": "{\"entities\": [{\"text\": \"clear cell adenocarcinoma\", \"type\": \"Disease\"}, {\"text\": \"DES\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05080", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The effects of the adjunctive bupropion on male sexual dysfunction induced by a selective serotonin reuptake inhibitor: a double - blind placebo - controlled and randomized study.", "completion": "{\"entities\": [{\"text\": \"bupropion\", \"type\": \"Chemical\"}, {\"text\": \"sexual dysfunction\", \"type\": \"Disease\"}, {\"text\": \"selective serotonin reuptake inhibitor\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01068", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Study of the role of vitamin B12 and folinic acid supplementation in preventing hematologic toxicity of zidovudine.", "completion": "{\"entities\": [{\"text\": \"vitamin B12\", \"type\": \"Chemical\"}, {\"text\": \"folinic acid\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}, {\"text\": \"zidovudine\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00119", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Arterial PO2 decreased in both groups.", "completion": "{\"entities\": [{\"text\": \"PO2\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00737", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: INTERVENTION (S ): Ophthalmic examination after CC therapy.", "completion": "{\"entities\": [{\"text\": \"CC\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04307", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: LY274614, 3SR,4aRS,6SR,8aRS-6-[phosphonomethyl]decahydr oisoquinoline-3- carboxylic acid, has been described as a potent antagonist of the N-methyl-D-aspartate (NMDA) subtype of glutamate receptor.", "completion": "{\"entities\": [{\"text\": \"LY274614\", \"type\": \"Chemical\"}, {\"text\": \"3SR,4aRS,6SR,8aRS-6-[phosphonomethyl]decahydr oisoquinoline-3- carboxylic acid\", \"type\": \"Chemical\"}, {\"text\": \"N-methyl-D-aspartate\", \"type\": \"Chemical\"}, {\"text\": \"NMDA\", \"type\": \"Chemical\"}, {\"text\": \"glutamate\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-reassigned-03185", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 9% NaCl was given i.", "completion": "{\"entities\": [{\"text\": \"NaCl\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04437", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Seizure susceptibility varies among inbred mouse strains.", "completion": "{\"entities\": [{\"text\": \"Seizure\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04628", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: He bought 25 g of carbachol as pure substance in a pharmacy, and the father was administered 400 to 500 mg.", "completion": "{\"entities\": [{\"text\": \"carbachol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01268", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Centrally acting alpha - 2 adrenergic agonists are one of several pharmacologic agents used in the treatment of spasticity related to disorders of the central nervous system.", "completion": "{\"entities\": [{\"text\": \"spasticity\", \"type\": \"Disease\"}, {\"text\": \"disorders of the central nervous system\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00947", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A 78 - year - old with healed septal necrosis suffered a recurrent myocardial infarction of the anterior wall following the administration of isosorbide dinitrate 5 mg sublingually.", "completion": "{\"entities\": [{\"text\": \"necrosis\", \"type\": \"Disease\"}, {\"text\": \"myocardial infarction\", \"type\": \"Disease\"}, {\"text\": \"isosorbide dinitrate\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02091", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Acute vanishing bile duct syndrome is a rare but established cause of progressive cholestasis in adults, is most often drug or toxin related, and is of unknown pathogenesis.", "completion": "{\"entities\": [{\"text\": \"vanishing bile duct\", \"type\": \"Disease\"}, {\"text\": \"cholestasis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01220", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: p .), administered 20 min before the training session, prevented amnesia induced by both the non selective antimuscarinic drug scopolamine and the M1 - selective antagonist S-(-)-ET-126.", "completion": "{\"entities\": [{\"text\": \"amnesia\", \"type\": \"Disease\"}, {\"text\": \"scopolamine\", \"type\": \"Chemical\"}, {\"text\": \"S-(-)-ET-126\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04293", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Seizures induced by the cocaine metabolite benzoylecgonine in rats.", "completion": "{\"entities\": [{\"text\": \"Seizures\", \"type\": \"Disease\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"benzoylecgonine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02895", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: p .) does not antagonize the reserpine hypothermia in mice and does not potentiate the 5-hydroxytryptophan head twitches in rats.", "completion": "{\"entities\": [{\"text\": \"reserpine\", \"type\": \"Chemical\"}, {\"text\": \"hypothermia\", \"type\": \"Disease\"}, {\"text\": \"5-hydroxytryptophan\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02085", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Twenty - three h postoperatively he developed a brief self - limited seizure.", "completion": "{\"entities\": [{\"text\": \"seizure\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03058", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These findings suggest that disruption of the blood - brain barrier during acute hypertension is not related to the synthesis / release of bradykinin", "completion": "{\"entities\": [{\"text\": \"hypertension\", \"type\": \"Disease\"}, {\"text\": \"bradykinin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00740", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A search of the literature on the thromboembolic complications of CC does not include this severe ophthalmic complication, although mild visual disturbance after CC intake is not uncommon.", "completion": "{\"entities\": [{\"text\": \"thromboembolic\", \"type\": \"Disease\"}, {\"text\": \"CC\", \"type\": \"Chemical\"}, {\"text\": \"visual disturbance\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03214", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Rhabdomyolysis is a potentially lethal syndrome that psychiatric patients seem predisposed to develop.", "completion": "{\"entities\": [{\"text\": \"Rhabdomyolysis\", \"type\": \"Disease\"}, {\"text\": \"psychiatric\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01789", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pretreatment with the D2 agonist PHNO enhanced nicotine - induced hyperactivity, whereas the D1 agonist SKF 38393 had no effect.", "completion": "{\"entities\": [{\"text\": \"PHNO\", \"type\": \"Chemical\"}, {\"text\": \"nicotine\", \"type\": \"Chemical\"}, {\"text\": \"hyperactivity\", \"type\": \"Disease\"}, {\"text\": \"SKF 38393\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03093", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Compared with sham - operated controls, lesions significantly (p < 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02926", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: In this study, WR242511 was administered intravenously (IV) in 2 female and 4 male rhesus monkeys in doses of 3.", "completion": "{\"entities\": [{\"text\": \"WR242511\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01901", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Based on these data, a plan of management was developed that allows effective yet safe administration of deferoxamine.", "completion": "{\"entities\": [{\"text\": \"deferoxamine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01387", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We present a patient with pseudoacromegaly that resulted from the long - term use of minoxidil at an unusually high dose.", "completion": "{\"entities\": [{\"text\": \"pseudoacromegaly\", \"type\": \"Disease\"}, {\"text\": \"minoxidil\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00130", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In six conscious, trained dogs, maintained on a normal sodium intake of 2 to 4 mEq / kg / day, sympathetic activity was assessed as the release rate of norepinephrine and epinephrine during 15 - minute i.", "completion": "{\"entities\": [{\"text\": \"sodium\", \"type\": \"Chemical\"}, {\"text\": \"norepinephrine\", \"type\": \"Chemical\"}, {\"text\": \"epinephrine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03273", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Dexamethasone (10 microg / kg per day, s.", "completion": "{\"entities\": [{\"text\": \"Dexamethasone\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02834", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Orthostatic hypotension was ameliorated 4 days after withdrawal of selegiline and totally abolished 7 days after discontinuation of the drug.", "completion": "{\"entities\": [{\"text\": \"Orthostatic hypotension\", \"type\": \"Disease\"}, {\"text\": \"selegiline\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02544", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In 10 of 11 patients, BAEP waves II / III - V completely disappeared within 2 to 25 min after papaverine.", "completion": "{\"entities\": [{\"text\": \"papaverine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02534", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Adverse effects of topical papaverine on auditory nerve function.", "completion": "{\"entities\": [{\"text\": \"papaverine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02971", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Inter - observer variability was measured in a series of 10 healthy subjects.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-reassigned-03472", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: v .)- treated normal mice.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04403", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Interestingly, estradiol also induced PRL - R, SOCS - 3, and CIS mRNA levels independently.", "completion": "{\"entities\": [{\"text\": \"estradiol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03536", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Ten rats received saline as a control group.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00392", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 01 ), and the degree of hypotension due to PGE1 remained constant until 60 min after its discontinuation.", "completion": "{\"entities\": [{\"text\": \"hypotension\", \"type\": \"Disease\"}, {\"text\": \"PGE1\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04056", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, the long - term use of this dopamine precursor is complicated by highly disabling fluctuations and dyskinesias.", "completion": "{\"entities\": [{\"text\": \"dopamine\", \"type\": \"Chemical\"}, {\"text\": \"dyskinesias\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01988", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In all the experiments, the attenuation of the lithium - induced diabetes-insipidus-like syndrome by amiloride was accompanied by a reduction of the ratio between the lithium concentration in the renal medulla and its levels in the blood and an elevation in the plasma potassium level.", "completion": "{\"entities\": [{\"text\": \"lithium\", \"type\": \"Chemical\"}, {\"text\": \"diabetes-insipidus-like syndrome\", \"type\": \"Disease\"}, {\"text\": \"amiloride\", \"type\": \"Chemical\"}, {\"text\": \"potassium\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03066", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Withdrawal-emergent rabbit syndrome during dose reduction of risperidone.", "completion": "{\"entities\": [{\"text\": \"Withdrawal-emergent rabbit syndrome\", \"type\": \"Disease\"}, {\"text\": \"risperidone\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04635", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: High doses of atropine (up to 50 mg per 24 hours ), adrenaline and dopamine were necessary.", "completion": "{\"entities\": [{\"text\": \"atropine\", \"type\": \"Chemical\"}, {\"text\": \"adrenaline\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03988", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Prenatal exposure to non - selective COX inhibitors increases the risk of VSD and MD when compared to historic control but not with selective COX - 2 inhibitors.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01706", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, unlike these latter, SSR103800 did not produce catalepsy (retention on the bar test) up to 30 mg / kg p.", "completion": "{\"entities\": [{\"text\": \"SSR103800\", \"type\": \"Chemical\"}, {\"text\": \"catalepsy\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01691", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Development of ocular myasthenia during pegylated interferon and ribavirin treatment for chronic hepatitis C.", "completion": "{\"entities\": [{\"text\": \"ocular myasthenia\", \"type\": \"Disease\"}, {\"text\": \"pegylated interferon\", \"type\": \"Chemical\"}, {\"text\": \"ribavirin\", \"type\": \"Chemical\"}, {\"text\": \"chronic hepatitis C\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03905", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: p .). Climbing behavior induced by apomorphine was reduced in animals treated with THP.", "completion": "{\"entities\": [{\"text\": \"apomorphine\", \"type\": \"Chemical\"}, {\"text\": \"THP\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05054", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Effect of humoral modulators of morphine - induced increase in locomotor activity of mice.", "completion": "{\"entities\": [{\"text\": \"morphine\", \"type\": \"Chemical\"}, {\"text\": \"increase in locomotor activity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00818", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The median duration of ATT before ALF was 30 (7 - 350) days.", "completion": "{\"entities\": [{\"text\": \"ALF\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01154", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0001) decrease in creatinine clearance was noted compared to controls.", "completion": "{\"entities\": [{\"text\": \"creatinine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02923", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Toxicity in rhesus monkeys following administration of the 8-aminoquinoline 8-[(4-amino-l-methylbutyl)amino]- 5-(l-hexyloxy)-6-methoxy-4-methylquinoline (WR242511 ). INTRODUCTION: Many substances that form methemoglobin (MHb) effectively counter cyanide (CN) toxicity.", "completion": "{\"entities\": [{\"text\": \"Toxicity\", \"type\": \"Disease\"}, {\"text\": \"8-aminoquinoline\", \"type\": \"Chemical\"}, {\"text\": \"8-[(4-amino-l-methylbutyl)amino]- 5-(l-hexyloxy)-6-methoxy-4-methylquinoline\", \"type\": \"Chemical\"}, {\"text\": \"WR242511\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-03495", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: MATERIALS AND METHODS: From November 2005 to September 2007, 8 patients (5 men and 3 women) were diagnosed as having metronidazole - induced encephalopathy (age range; 43 - 78 years ). They had been taking metronidazole (total dosage, 45 - 120 g; duration, 30 days to 2 months) to treat the infection in various organs.", "completion": "{\"entities\": [{\"text\": \"metronidazole\", \"type\": \"Chemical\"}, {\"text\": \"encephalopathy\", \"type\": \"Disease\"}, {\"text\": \"infection\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04997", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It is recommended that either glycopyrrolate 10 micrograms kg - 1 or atropine 20 micrograms kg - 1 i.", "completion": "{\"entities\": [{\"text\": \"glycopyrrolate\", \"type\": \"Chemical\"}, {\"text\": \"atropine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04833", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The results of detailed laboratory tests and evaluations of various quantitative and qualitative tolerability parameters were not indicative of toxic effects.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01444", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The enhanced alpha-methyldopa hypotension in Ovx rats was paralleled with further reduction in SDRR and a reduced locomotor activity.", "completion": "{\"entities\": [{\"text\": \"alpha-methyldopa\", \"type\": \"Chemical\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}, {\"text\": \"a reduced locomotor activity\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02763", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Neuromuscular monitoring was used in two patients.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04587", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The incidence of preneoplastic nodules and of hepatocellular carcinomas was 10% and 37 %, respectively, in rats fed the plain choline - devoid diet, and 17% and 30 %, in rats fed the phenobarbital - containing choline - devoid diet.", "completion": "{\"entities\": [{\"text\": \"hepatocellular carcinomas\", \"type\": \"Disease\"}, {\"text\": \"choline\", \"type\": \"Chemical\"}, {\"text\": \"phenobarbital\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04433", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: The data on TR (-) rats indicate that Pgp plays an important role in the compensation of MRP2 deficiency in the BBB.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02165", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This experiment is discussed with regard to the hypothesis that ultrasound production is the acoustic by - product of a physiological maneuver that compensates for clonidine", "completion": "{\"entities\": [{\"text\": \"clonidine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04048", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The patients were randomly allocated to one of three groups; those in group A (n = 10) were subjected to controlled hypotension alone, those in group B (n = 10) to haemodilution alone and those in group C (n = 10) to both controlled hypotension and haemodilution.", "completion": "{\"entities\": [{\"text\": \"hypotension\", \"type\": \"Disease\"}, {\"text\": \"haemodilution\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03962", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We report the case of a 30 - year - old Caucasian man who came to the emergency department in atrial fibrillation with rapid ventricular response.", "completion": "{\"entities\": [{\"text\": \"atrial fibrillation\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05051", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Improvement was noted with cessation of therapy.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00065", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 6 patients presented clinical symptoms of visual or auditory toxicity.", "completion": "{\"entities\": [{\"text\": \"visual or auditory toxicity\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00126", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Seizures induced by hexafluorodiethyl ether (HFDE) were also found to be a more sensitive measure of protection by CBZ than seizures induced by maximal electroshock (MES ). Oral administration of CBZ as an aqueous suspension every 8 h at a dose of 250 mg / kg was continuously protective against HFDE - induced seizures and was minimally toxic as measured by weight gain over 8 weeks of treatment.", "completion": "{\"entities\": [{\"text\": \"Seizures\", \"type\": \"Disease\"}, {\"text\": \"hexafluorodiethyl ether\", \"type\": \"Chemical\"}, {\"text\": \"HFDE\", \"type\": \"Chemical\"}, {\"text\": \"CBZ\", \"type\": \"Chemical\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}, {\"text\": \"weight gain\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-04896", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Levodopa - induced dyskinesias (LIDs) present a major problem for the long - term management of Parkinson's disease (PD) patients.", "completion": "{\"entities\": [{\"text\": \"Levodopa\", \"type\": \"Chemical\"}, {\"text\": \"dyskinesias\", \"type\": \"Disease\"}, {\"text\": \"LIDs\", \"type\": \"Disease\"}, {\"text\": \"Parkinson's disease\", \"type\": \"Disease\"}, {\"text\": \"PD\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-05018", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Flestolol effectively reduced heart rate in patients with supraventricular tachyarrhythmia.", "completion": "{\"entities\": [{\"text\": \"Flestolol\", \"type\": \"Chemical\"}, {\"text\": \"supraventricular tachyarrhythmia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01597", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Clonidine inhibited the native pacemaker current (I (f )) in isolated sinoatrial node pacemaker cells and the I (f )- generating hyperpolarization - activated cyclic nucleotide - gated (HCN) 2 and HCN4 channels in transfected HEK293 cells.", "completion": "{\"entities\": [{\"text\": \"Clonidine\", \"type\": \"Chemical\"}, {\"text\": \"cyclic nucleotide\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00440", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the vitro human platelet aggregations induced by the agonists used in tests, TET and FAN showed the inhibitions dose dependently.", "completion": "{\"entities\": [{\"text\": \"platelet aggregations\", \"type\": \"Disease\"}, {\"text\": \"TET\", \"type\": \"Chemical\"}, {\"text\": \"FAN\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01566", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5, adjusted for age, years since menopause, smoking, and body mass index ). The association remained after additional adjustment for diabetes, cholesterol level, systolic blood pressure, or alcohol use.", "completion": "{\"entities\": [{\"text\": \"diabetes\", \"type\": \"Disease\"}, {\"text\": \"cholesterol\", \"type\": \"Chemical\"}, {\"text\": \"alcohol\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00196", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The rigidity was considerably decreased in both groups after 20 days' treatment.", "completion": "{\"entities\": [{\"text\": \"rigidity\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04596", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Doxorubicin is an effective anticancer chemotherapeutic agent known to cause acute and chronic cardiomyopathy.", "completion": "{\"entities\": [{\"text\": \"Doxorubicin\", \"type\": \"Chemical\"}, {\"text\": \"cardiomyopathy\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00060", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Although initially thought to be free of extrapyramidal side effects, sulpiride - induced tardive dyskinesia and parkinsonism have been reported occasionally.", "completion": "{\"entities\": [{\"text\": \"sulpiride\", \"type\": \"Chemical\"}, {\"text\": \"tardive dyskinesia\", \"type\": \"Disease\"}, {\"text\": \"parkinsonism\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-05187", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: GLEPP1 receptor tyrosine phosphatase (Ptpro) in rat PAN nephrosis.", "completion": "{\"entities\": [{\"text\": \"tyrosine\", \"type\": \"Chemical\"}, {\"text\": \"PAN\", \"type\": \"Chemical\"}, {\"text\": \"nephrosis\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02496", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The effects of METH in CX3CR1 knockout mice were not gender - dependent and did not extend beyond the striatum.", "completion": "{\"entities\": [{\"text\": \"METH\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01543", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: INTERVENTION AND OUTCOME: An 18 - gauge Touhy needle was inserted until loss of resistance occurred at the L4 - 5 level.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02618", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Asenapine is approved by the Food and Drugs Administration in adults for acute treatment of schizophrenia or of manic or mixed episodes associated with bipolar I disorder with or without psychotic features.", "completion": "{\"entities\": [{\"text\": \"Asenapine\", \"type\": \"Chemical\"}, {\"text\": \"schizophrenia\", \"type\": \"Disease\"}, {\"text\": \"manic\", \"type\": \"Disease\"}, {\"text\": \"bipolar I disorder\", \"type\": \"Disease\"}, {\"text\": \"psychotic\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-04193", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: DISCUSSION: To our knowledge, this is the first reported case of venlafaxine overdose that resulted in a generalized seizure.", "completion": "{\"entities\": [{\"text\": \"venlafaxine\", \"type\": \"Chemical\"}, {\"text\": \"overdose\", \"type\": \"Disease\"}, {\"text\": \"seizure\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03045", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Seven cases of procainamide - induced polymorphous ventricular tachycardia are presented.", "completion": "{\"entities\": [{\"text\": \"procainamide\", \"type\": \"Chemical\"}, {\"text\": \"ventricular tachycardia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00902", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The average FEV1 increases during the 6 - hour observation period were 18% for ipratropium and 8% for theophylline.", "completion": "{\"entities\": [{\"text\": \"ipratropium\", \"type\": \"Chemical\"}, {\"text\": \"theophylline\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00854", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Electrophysiological recordings showed that microinjection of neurotensin induced excitation of pallidal neurons in the presence of systemic haloperidol administration.", "completion": "{\"entities\": [{\"text\": \"neurotensin\", \"type\": \"Chemical\"}, {\"text\": \"haloperidol\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04319", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: No underlying infective or biochemical cause could be found.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04815", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Conservative treatment, including bladder irrigation with physiological saline and instillation of prostaglandin F2 alpha, failed to totally control hemorrhage.", "completion": "{\"entities\": [{\"text\": \"prostaglandin F2 alpha\", \"type\": \"Chemical\"}, {\"text\": \"hemorrhage\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01171", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: From October 1993 to November 1995, we treated 13 patients with previously chemotherapy - treated metastatic breast cancer by mitoxantrone, 12 mg / m2, on day 1 and continuous infusion of 5-FU, 3000 mg / m2, together with leucovorin, 300 mg / m2, for 48 h from day 1 to 2.", "completion": "{\"entities\": [{\"text\": \"breast cancer\", \"type\": \"Disease\"}, {\"text\": \"mitoxantrone\", \"type\": \"Chemical\"}, {\"text\": \"5-FU\", \"type\": \"Chemical\"}, {\"text\": \"leucovorin\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02215", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Taken together, these events undoubtedly establish GSPE", "completion": "{\"entities\": [{\"text\": \"GSPE\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03675", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The drugs commonly used are cyclophosphamide and chlorambucil (alkylating agents ), azathioprine (purine analogue ), and methotrexate (folic acid analogue ). There is evidence that all four immunosuppressive drugs can reduce synovitis, but disease activity almost always recurs after therapy is stopped.", "completion": "{\"entities\": [{\"text\": \"cyclophosphamide\", \"type\": \"Chemical\"}, {\"text\": \"chlorambucil\", \"type\": \"Chemical\"}, {\"text\": \"alkylating agents\", \"type\": \"Chemical\"}, {\"text\": \"azathioprine\", \"type\": \"Chemical\"}, {\"text\": \"purine\", \"type\": \"Chemical\"}, {\"text\": \"methotrexate\", \"type\": \"Chemical\"}, {\"text\": \"folic acid\", \"type\": \"Chemical\"}, {\"text\": \"synovitis\", \"type\": \"Disease\"}]}", "n_entities": 8}
{"ref": "bc5cdr-train-03040", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Because drug - induced de novo absence seizure is rare, pro - absence drugs can only be considered a promoting factor.", "completion": "{\"entities\": [{\"text\": \"absence seizure\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02322", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Population responses in granule cells of the dentate gyrus were examined in transverse slices of the ventral hippocampus from pilocarpine - treated and untreated mice.", "completion": "{\"entities\": [{\"text\": \"pilocarpine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00865", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05, decreased arterial blood pressure, but did not significantly alter heart rate, cardiac output, systemic vascular resistance, or QS / QT.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02018", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Prospective study of the long - term effects of somatostatin analog (octreotide) on gallbladder function and gallstone formation in Chinese acromegalic patients.", "completion": "{\"entities\": [{\"text\": \"octreotide\", \"type\": \"Chemical\"}, {\"text\": \"gallstone\", \"type\": \"Disease\"}, {\"text\": \"acromegalic\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02741", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Untreated group 3 rats exhibited a progressive reduction in GFR (0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04964", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 %(50 mg ). Venous discomfort was assessed with a visual analogue scale (VAS) 5 - 15 sec after commencing propofol administration using an infusion pump (rate 1000 micrograms.", "completion": "{\"entities\": [{\"text\": \"propofol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01242", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Totals of 128 cases and 650 controls were analysed for repeat use and 135 cases and 622 controls for switching patterns.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03718", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pharmacokinetic analyses in 21 patients revealed Pirarubicin plasma T 1 / 2 alpha (+/- SE) of 2.", "completion": "{\"entities\": [{\"text\": \"Pirarubicin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00024", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Galanthamine hydrobromide, a longer acting anticholinesterase drug, in the treatment of the central effects of scopolamine (Hyoscine ). Galanthamine hydrobromide, an anticholinesterase drug capable of penetrating the blood - brain barrier, was used in a patient demonstrating central effects of scopolamine (hyoscine) overdosage.", "completion": "{\"entities\": [{\"text\": \"Galanthamine hydrobromide\", \"type\": \"Chemical\"}, {\"text\": \"scopolamine\", \"type\": \"Chemical\"}, {\"text\": \"Hyoscine\", \"type\": \"Chemical\"}, {\"text\": \"hyoscine\", \"type\": \"Chemical\"}, {\"text\": \"overdosage\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-02142", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: During activation with Na +, the Vmax remained unchanged, however the K (Na) increased by 50 %, indicating a profound decrease in the affinity of the Na +- binding site in NO - deficient rats.", "completion": "{\"entities\": [{\"text\": \"Na\", \"type\": \"Chemical\"}, {\"text\": \"K\", \"type\": \"Chemical\"}, {\"text\": \"NO\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04346", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Twenty - three hours after heart transplantation, life - threatening acute right heart failure was diagnosed in a patient requiring continuous venovenous hemodiafiltration (CVVHDF ). Increasing doses of catecholamines, sedatives, and muscle relaxants administered through a central venous catheter were ineffective.", "completion": "{\"entities\": [{\"text\": \"right heart failure\", \"type\": \"Disease\"}, {\"text\": \"catecholamines\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03811", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: NRA0160 and clozapine significantly shortened the phencyclidine (PCP )- induced prolonged swimming latency in rats in a water maze task.", "completion": "{\"entities\": [{\"text\": \"NRA0160\", \"type\": \"Chemical\"}, {\"text\": \"clozapine\", \"type\": \"Chemical\"}, {\"text\": \"phencyclidine\", \"type\": \"Chemical\"}, {\"text\": \"PCP\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04860", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, future investigations are necessary to exactly analyze the biochemical mechanisms by which PDTC", "completion": "{\"entities\": [{\"text\": \"PDTC\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00662", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Mean urinary protein of patients who returned to dialysis was 1.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04256", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Such interactions may result in serious cardiovascular complications even after cessation of an infusion of ritodrine.", "completion": "{\"entities\": [{\"text\": \"cardiovascular complications\", \"type\": \"Disease\"}, {\"text\": \"ritodrine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02667", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thirty male Sprague - Dawley rats were divided randomly into four treatment groups: saline, dexamethasone (dex ), allopurinol plus saline, and allopurinol plus dex.", "completion": "{\"entities\": [{\"text\": \"dex\", \"type\": \"Chemical\"}, {\"text\": \"dexamethasone\", \"type\": \"Chemical\"}, {\"text\": \"allopurinol\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01007", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 1 kPa (mean +/- SEM ). Controlled hypotension to an average MAP of 50 - 55 mm Hg was induced by increasing the dose of isoflurane, and maintained at an inspired concentration of 2.", "completion": "{\"entities\": [{\"text\": \"hypotension\", \"type\": \"Disease\"}, {\"text\": \"Hg\", \"type\": \"Chemical\"}, {\"text\": \"isoflurane\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02082", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, we suggest that a low solution concentration should be preferred for unilateral spinal anaesthesia with a hyperbaric anaesthetic solution (if pencil - point needle and slow injection rate are employed ), in order to minimize the risk of a localized high peak anaesthetic concentration, which might lead to a transient neurological deficit", "completion": "{\"entities\": [{\"text\": \"neurological deficit\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02943", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Tonotopic organization is an essential feature of the primary auditory area (A1) of primate cortex.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02884", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Manifestations regressed spontaneously under surveillance in the hospital.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01760", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Acetylsalicylic acid, dipyridamole, and hydrocortisone", "completion": "{\"entities\": [{\"text\": \"Acetylsalicylic acid\", \"type\": \"Chemical\"}, {\"text\": \"dipyridamole\", \"type\": \"Chemical\"}, {\"text\": \"hydrocortisone\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03225", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Differential impact of immune escape mutations G145R and P120T on the replication of lamivudine - resistant hepatitis B virus e antigen - positive and - negative strains.", "completion": "{\"entities\": [{\"text\": \"lamivudine\", \"type\": \"Chemical\"}, {\"text\": \"hepatitis B virus e antigen\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04359", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Perceived pain intensity is modulated by attention.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02616", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These effects may be relevant in the treatment of cocaine", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02948", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The actual frequencies deafened were determined by the loss of tone - burst elicited auditory brainstem responses.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04567", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Mouse strain - dependent effect of amantadine on motility and brain biogenic amines.", "completion": "{\"entities\": [{\"text\": \"amantadine\", \"type\": \"Chemical\"}, {\"text\": \"amines\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04942", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Prolactin results were compared with those of a previous personal cohort of 1, 340 patients with erectile dysfunction and systematic prolactin determination.", "completion": "{\"entities\": [{\"text\": \"erectile dysfunction\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01124", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These studies suggest that both phenacetin and acetaminophen may contribute to the burden of ESRD, with the risk of the latter being somewhat less than that of the former.", "completion": "{\"entities\": [{\"text\": \"phenacetin\", \"type\": \"Chemical\"}, {\"text\": \"acetaminophen\", \"type\": \"Chemical\"}, {\"text\": \"ESRD\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04122", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Recently, however, we have had an increase of patients who are presenting after OLTX with end-stage renal disease (ESRD ). This retrospective study examines the incidence and treatment of ESRD and chronic renal failure (CRF) in OLTX patients.", "completion": "{\"entities\": [{\"text\": \"end-stage renal disease\", \"type\": \"Disease\"}, {\"text\": \"ESRD\", \"type\": \"Disease\"}, {\"text\": \"chronic renal failure\", \"type\": \"Disease\"}, {\"text\": \"CRF\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00746", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Eight healthy volunteers inhaled nicotine in darkness during a functional magnetic resonance imaging (fMRI) experiment; eye movements were registered using video - oculography.", "completion": "{\"entities\": [{\"text\": \"nicotine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01126", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A lower relative risk would be expected for acetaminophen if the risk of both drugs in combination with other analgesics was higher than the risk of either agent alone.", "completion": "{\"entities\": [{\"text\": \"acetaminophen\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03166", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 2 %). World Health Organization Grade 3 - 4 neutropenia and thrombocytopenia occurred in 39.", "completion": "{\"entities\": [{\"text\": \"neutropenia\", \"type\": \"Disease\"}, {\"text\": \"thrombocytopenia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04568", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The effect of amantadine hydrochloride, injected i.", "completion": "{\"entities\": [{\"text\": \"amantadine hydrochloride\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-reassigned-05250", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 385) with glimepiride, 0.", "completion": "{\"entities\": [{\"text\": \"glimepiride\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00626", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The latter two deficits remained significant after controlling for other drug use.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04292", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The findings of this study indicate that the drug is able to antagonize impairment of attention and memory induced by scopolamine", "completion": "{\"entities\": [{\"text\": \"impairment of attention and memory\", \"type\": \"Disease\"}, {\"text\": \"scopolamine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03901", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05 ). Pretreatment with RAMH (5 microg i.", "completion": "{\"entities\": [{\"text\": \"RAMH\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03117", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We propose that the paracetamol dose should not exceed 2 g / day in such patients and that their liver function should be monitored closely while being treated with paracetamol", "completion": "{\"entities\": [{\"text\": \"paracetamol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02565", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: To this end, doxorubicin (15 mug / g body wt) was injected intravenously into gene - targeted mice lacking SGK1 (sgk1 (-/-)) and their wild - type littermates (sgk1 (+/+)). Doxorubicin treatment resulted in heavy proteinuria (> 100 mg protein / mg crea) in 15 / 44 of sgk1 (+/+) and 15 / 44 of sgk1 (-/-) mice leading to severe nephrotic syndrome with ascites, lipidemia, and hypoalbuminemia in both genotypes.", "completion": "{\"entities\": [{\"text\": \"doxorubicin\", \"type\": \"Chemical\"}, {\"text\": \"Doxorubicin\", \"type\": \"Chemical\"}, {\"text\": \"proteinuria\", \"type\": \"Disease\"}, {\"text\": \"nephrotic syndrome\", \"type\": \"Disease\"}, {\"text\": \"ascites\", \"type\": \"Disease\"}, {\"text\": \"lipidemia\", \"type\": \"Disease\"}, {\"text\": \"hypoalbuminemia\", \"type\": \"Disease\"}]}", "n_entities": 7}
{"ref": "bc5cdr-train-03269", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the present study, we investigated whether 50 mg / kg per day, p.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02048", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The possible influence of the hepatic damage, mainly hyperammonemia, upon the development of valproate encephalopathy", "completion": "{\"entities\": [{\"text\": \"hepatic damage\", \"type\": \"Disease\"}, {\"text\": \"hyperammonemia\", \"type\": \"Disease\"}, {\"text\": \"valproate\", \"type\": \"Chemical\"}, {\"text\": \"encephalopathy\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03498", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Initial MRIs showed abnormal high signal intensities on DWI and FLAIR (or T2 - weighted image) at the dentate nucleus (8 / 8 ), inferior colliculus (6 / 8 ), corpus callosum (2 / 8 ), pons (2 / 8 ), medulla (1 / 8 ), and bilateral cerebral white matter (1 / 8 ). High - signal intensity lesions on DWI tended to show low signal intensity on ADC map (3 / 4 ), but in one patient, high signal intensity was shown at bilateral dentate nuclei on not only DWI but also ADC map.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04653", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 1 %), more than twice as many preferred rizatriptan to ergotamine / caffeine (69.", "completion": "{\"entities\": [{\"text\": \"rizatriptan\", \"type\": \"Chemical\"}, {\"text\": \"ergotamine\", \"type\": \"Chemical\"}, {\"text\": \"caffeine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04646", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: For the first time, an analytical method for the determination of carbachol in plasma and urine has been developed.", "completion": "{\"entities\": [{\"text\": \"carbachol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02075", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05 ). The average hearing loss for speech frequencies was about 10 dB after prilocaine and 15 dB after bupivacaine.", "completion": "{\"entities\": [{\"text\": \"hearing loss\", \"type\": \"Disease\"}, {\"text\": \"prilocaine\", \"type\": \"Chemical\"}, {\"text\": \"bupivacaine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00574", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In conclusion, ENaC mRNA expression, especially alphaENaC, is increased in the very early phase of the experimental model of PAN - induced nephrotic syndrome in rats, but appears to escape from the regulation by aldosterone", "completion": "{\"entities\": [{\"text\": \"PAN\", \"type\": \"Chemical\"}, {\"text\": \"nephrotic syndrome\", \"type\": \"Disease\"}, {\"text\": \"aldosterone\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03839", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Optimization of levodopa therapy.", "completion": "{\"entities\": [{\"text\": \"levodopa\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01319", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Patients aged 18 years or older treated with prochlorperazine for headache, nausea, or vomiting were eligible for inclusion.", "completion": "{\"entities\": [{\"text\": \"prochlorperazine\", \"type\": \"Chemical\"}, {\"text\": \"headache\", \"type\": \"Disease\"}, {\"text\": \"nausea\", \"type\": \"Disease\"}, {\"text\": \"vomiting\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03215", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The clinical signs and symptoms, typical laboratory features, and complications of rhabdomyolysis are presented.", "completion": "{\"entities\": [{\"text\": \"rhabdomyolysis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02650", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Learning of rats under amnesia caused by pentobarbital.", "completion": "{\"entities\": [{\"text\": \"amnesia\", \"type\": \"Disease\"}, {\"text\": \"pentobarbital\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00152", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Patients with large pelvic tumor", "completion": "{\"entities\": [{\"text\": \"pelvic tumor\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01368", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Hypertension was observed in animals that had a reduction in glomeruli as well as in a group that did not have a reduction in glomerular number, suggesting that a reduction in glomerular number is not the sole cause for the development of hypertension", "completion": "{\"entities\": [{\"text\": \"Hypertension\", \"type\": \"Disease\"}, {\"text\": \"reduction in glomerular number\", \"type\": \"Disease\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01702", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This study aimed at investigating the potential antipsychotic - like properties of SSR103800, with a particular focus on models of hyperactivity, involving either drug challenge (ie, amphetamine and MK-801) or transgenic mice (ie, NMDA Nr1 (neo -/-) and DAT (-/-)). Results showed that SSR103800 (10 - 30 mg / kg p.", "completion": "{\"entities\": [{\"text\": \"SSR103800\", \"type\": \"Chemical\"}, {\"text\": \"hyperactivity\", \"type\": \"Disease\"}, {\"text\": \"amphetamine\", \"type\": \"Chemical\"}, {\"text\": \"MK-801\", \"type\": \"Chemical\"}, {\"text\": \"NMDA\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-00114", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A randomized comparison of labetalol and nitroprusside for induced hypotension.", "completion": "{\"entities\": [{\"text\": \"labetalol\", \"type\": \"Chemical\"}, {\"text\": \"nitroprusside\", \"type\": \"Chemical\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04226", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The possible role of low pH as well as total volume as potential factors in causing neurotoxicity was evaluated.", "completion": "{\"entities\": [{\"text\": \"neurotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01459", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: The Multiple Outcomes of Raloxifene Evaluation, a multicenter, randomized, double - blind trial, enrolled 7, 705 postmenopausal women with osteoporosis.", "completion": "{\"entities\": [{\"text\": \"Raloxifene\", \"type\": \"Chemical\"}, {\"text\": \"osteoporosis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-04948", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The patient did not self medicate.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01537", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Therefore, DCE may prove to be a useful remedy for the management of cognitive dysfunctions on account of its multifarious beneficial effects such as, memory improving property, cholesterol", "completion": "{\"entities\": [{\"text\": \"DCE\", \"type\": \"Chemical\"}, {\"text\": \"cognitive dysfunctions\", \"type\": \"Disease\"}, {\"text\": \"cholesterol\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01649", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: These results indicate that noradrenergic signaling via beta - adrenergic receptors is required for cocaine - induced anxiety", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"anxiety\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03464", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Antagonism between interleukin 3 and erythropoietin in mice with azidothymidine - induced anemia and in bone marrow endothelial cells.", "completion": "{\"entities\": [{\"text\": \"azidothymidine\", \"type\": \"Chemical\"}, {\"text\": \"anemia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-04578", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Erdosteine was administered orally.", "completion": "{\"entities\": [{\"text\": \"Erdosteine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02960", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Aim of the study was to determine sensitivity, reproducibility, reference values and the agreement with a questionnaire.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02651", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Dissociated learning of rats in the normal state and the state of amnesia produced by pentobarbital (15 mg / kg, ip) was carried out.", "completion": "{\"entities\": [{\"text\": \"amnesia\", \"type\": \"Disease\"}, {\"text\": \"pentobarbital\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03338", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSION: Individual differences in renal ACE activity predict the severity of adriamycin - induced renal damage in this outbred rat strain.", "completion": "{\"entities\": [{\"text\": \"adriamycin\", \"type\": \"Chemical\"}, {\"text\": \"renal damage\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01616", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Terbutaline, a beta2 - adrenoceptor agonist used to arrest preterm labor, has been associated with increased concordance for autism in dizygotic twins.", "completion": "{\"entities\": [{\"text\": \"Terbutaline\", \"type\": \"Chemical\"}, {\"text\": \"preterm labor\", \"type\": \"Disease\"}, {\"text\": \"autism\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02978", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 53 ). Postural tremor showed no significant difference between the first and third session (P = 0.", "completion": "{\"entities\": [{\"text\": \"tremor\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00783", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 %) and its outcome favourable in most of the cases (82 %). The occurrence of this ADR was more frequent in patients aged between 61 and 80 years.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00944", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The restoration of continence was accompanied by a substantial rise in maximum urethral pressure, maximum urethral closure pressure, and functional urethral length.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02937", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Myoglobinuria was also observed following the 7.", "completion": "{\"entities\": [{\"text\": \"Myoglobinuria\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00889", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: With regard to spasm, the clinical findings are largely circumstantial, and the locus of cocaine - induced vasoconstriction remains speculative.", "completion": "{\"entities\": [{\"text\": \"spasm\", \"type\": \"Disease\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03885", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: c .) were used for studying climbing behavior and locomotor activities, respectively.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00777", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Some case reports are published in the literature but no systematic study from a sample of patients has been published.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03430", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Immunolocalization of 7H6 appears to closely correlate with paracellular permeability.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01227", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 6 - fold of the control value.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04062", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BMCs obtained from green fluorescent protein (GFP) transgenic mice or rats were transplanted intravenously after induction of status epilepticus (SE ). Spontaneous recurrent seizures (SRS) were monitored using Racine' s seizure severity scale.", "completion": "{\"entities\": [{\"text\": \"status epilepticus\", \"type\": \"Disease\"}, {\"text\": \"SE\", \"type\": \"Disease\"}, {\"text\": \"Spontaneous recurrent seizures\", \"type\": \"Disease\"}, {\"text\": \"seizure\", \"type\": \"Disease\"}, {\"text\": \"SRS\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-01371", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: Using the General Practice Research Database we conducted a cohort analysis and case - control study nested within a population of women aged between 15 and 39 years with acne, hirsutism or PCOS to estimate the risk of VTE associated with CPA / EE.", "completion": "{\"entities\": [{\"text\": \"acne\", \"type\": \"Disease\"}, {\"text\": \"hirsutism\", \"type\": \"Disease\"}, {\"text\": \"PCOS\", \"type\": \"Disease\"}, {\"text\": \"VTE\", \"type\": \"Disease\"}, {\"text\": \"CPA\", \"type\": \"Chemical\"}, {\"text\": \"EE\", \"type\": \"Chemical\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-00514", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: An association between the use of oral contraceptives and the risk of myocardial infarction has been found in some, but not all, studies.", "completion": "{\"entities\": [{\"text\": \"oral contraceptives\", \"type\": \"Chemical\"}, {\"text\": \"myocardial infarction\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-02049", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 4 min after lindane administration.", "completion": "{\"entities\": [{\"text\": \"lindane\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04045", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Clinical and biochemical monitoring at regular intervals for evidence of hepatitis is advised during long term treatment with ketoconazole to prevent possible serious hepatic injury", "completion": "{\"entities\": [{\"text\": \"hepatitis\", \"type\": \"Disease\"}, {\"text\": \"ketoconazole\", \"type\": \"Chemical\"}, {\"text\": \"hepatic injury\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02701", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: AIM: The aim of the documentation of this clinical case is to make clinicians aware of\" meth mouth\" and the medical risks associated with this serious condition.", "completion": "{\"entities\": [{\"text\": \"meth mouth\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04361", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Here we show that perceived pain intensity in secondary hyperalgesia is decreased when attention is distracted away from the painful pinprick stimulus with a visual task.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"hyperalgesia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02112", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This paper attempts to examine and compare prevalence rates and symptom patterns of DSM substance - induced and other mood disorders.", "completion": "{\"entities\": [{\"text\": \"mood disorders\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03385", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A single - blind parenteral challenge with Triniol was positive in both patients after the administration of 1 ml of the drug, and negative with its excipients.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01585", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In all cases there was diffuse or multifocal up - regulation of MHC - I expression even in non - necrotic fibres.", "completion": "{\"entities\": [{\"text\": \"necrotic\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02855", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Reversibility of captopril - induced renal insufficiency after prolonged use in an unusual case of renovascular hypertension.", "completion": "{\"entities\": [{\"text\": \"captopril\", \"type\": \"Chemical\"}, {\"text\": \"renal insufficiency\", \"type\": \"Disease\"}, {\"text\": \"renovascular hypertension\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-05105", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 2) for the bupropion and 36.", "completion": "{\"entities\": [{\"text\": \"bupropion\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00169", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Given the influx of Southeast Asians into the United States, oxidant medications should be used with caution, especially if an infection", "completion": "{\"entities\": [{\"text\": \"infection\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03087", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: High - dose intravenous methotrexate is an effective treatment for the induction of remission after meningeal relapse in acute lymphoblastic leukemia", "completion": "{\"entities\": [{\"text\": \"methotrexate\", \"type\": \"Chemical\"}, {\"text\": \"acute lymphoblastic leukemia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02974", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Within healthy adults no age - dependency could be found (b = 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00857", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Antihypertensive drugs and depression: a reappraisal.", "completion": "{\"entities\": [{\"text\": \"depression\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01992", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: The widespread use of benzodiazepines has led to increasing recognition of their unwanted effects.", "completion": "{\"entities\": [{\"text\": \"benzodiazepines\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01472", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Raloxifene did not increase risk for cataracts (RR 0.", "completion": "{\"entities\": [{\"text\": \"Raloxifene\", \"type\": \"Chemical\"}, {\"text\": \"cataracts\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01080", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Because folinic acid was unlikely to be associated with this condition, neurotoxicity due to high - dose 5-fluorouracil was highly suspected.", "completion": "{\"entities\": [{\"text\": \"folinic acid\", \"type\": \"Chemical\"}, {\"text\": \"neurotoxicity\", \"type\": \"Disease\"}, {\"text\": \"5-fluorouracil\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03009", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Urgent fasciotomies were performed and the patient made an uneventful recovery with the withdrawal of simvastatin.", "completion": "{\"entities\": [{\"text\": \"simvastatin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02298", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Associated factors were co - treatment with other centrally antimuscarinic agents, poor clinical outcome, older age, and longer hospitalization (by 17.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04334", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: PURPOSE: This study was designed to establish a rat model of thoracic aortic aneurysm (TAA) by calcium chloride (CaCl(2) )- induced arterial injury and to explore the potential role of a disintegrin and metalloproteinase (ADAM ), matrix metalloproteinases (MMPs) and their endogenous inhibitors (TIMPs) in TAA formation.", "completion": "{\"entities\": [{\"text\": \"thoracic aortic aneurysm\", \"type\": \"Disease\"}, {\"text\": \"TAA\", \"type\": \"Disease\"}, {\"text\": \"calcium chloride\", \"type\": \"Chemical\"}, {\"text\": \"CaCl(2)\", \"type\": \"Chemical\"}, {\"text\": \"arterial injury\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-00931", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The thermal enhancement ratio calculated for antitumor activity was 1.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00055", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Electrocardiographic evidence of myocardial injury in psychiatrically hospitalized cocaine abusers.", "completion": "{\"entities\": [{\"text\": \"myocardial injury\", \"type\": \"Disease\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04699", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Post - mortem examination showed evidence of massive hepatocellular necrosis, acute hypersensitivity myocarditis, focal acute tubulo - interstitial nephritis and extensive bone marrow necrosis, with no evidence of malignancy.", "completion": "{\"entities\": [{\"text\": \"massive hepatocellular necrosis\", \"type\": \"Disease\"}, {\"text\": \"myocarditis\", \"type\": \"Disease\"}, {\"text\": \"nephritis\", \"type\": \"Disease\"}, {\"text\": \"bone marrow necrosis\", \"type\": \"Disease\"}, {\"text\": \"malignancy\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-04130", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 %). Compared with control patients, CRF and ESRD patients had higher preoperative serum creatinine levels, a greater percentage of patients with hepatorenal syndrome, higher percentage requirement for dialysis in the first 3 months postoperatively, and a higher 1 - year serum creatinine.", "completion": "{\"entities\": [{\"text\": \"CRF\", \"type\": \"Disease\"}, {\"text\": \"ESRD\", \"type\": \"Disease\"}, {\"text\": \"creatinine\", \"type\": \"Chemical\"}, {\"text\": \"hepatorenal syndrome\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02541", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Brainstem auditory evoked potentials (BAEPs) were routinely used to monitor cochlear nerve function during these operations.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-05077", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Suxamethonium induced prolonged apnea in a patient receiving electroconvulsive therapy.", "completion": "{\"entities\": [{\"text\": \"Suxamethonium\", \"type\": \"Chemical\"}, {\"text\": \"apnea\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02285", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Subjects (n = 139) were 72 women and 67 men, aged 40.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04186", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Clinical studies of pipe smokers and people using transdermal nicotine support the idea that toxins other than nicotine are the most important causes of acute cardiovascular events.", "completion": "{\"entities\": [{\"text\": \"nicotine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00836", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Exclusion criteria included CNS leukemic infiltration at diagnosis, therapy - related peripheral neuropathy, late - onset encephalopathy, or long - term neurocognitive defects.", "completion": "{\"entities\": [{\"text\": \"leukemic infiltration\", \"type\": \"Disease\"}, {\"text\": \"peripheral neuropathy\", \"type\": \"Disease\"}, {\"text\": \"encephalopathy\", \"type\": \"Disease\"}, {\"text\": \"neurocognitive defects\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00475", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: High doses of the vitamin K antagonist Warfarin are also known to cause calcification of the artery media, but at treatment times of 2 weeks or longer yet not at 1 week.", "completion": "{\"entities\": [{\"text\": \"vitamin K\", \"type\": \"Chemical\"}, {\"text\": \"Warfarin\", \"type\": \"Chemical\"}, {\"text\": \"calcification of the artery\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01027", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The second twin, a male, had some features of Potter's facies, hypoplastic lungs, absent kidneys and ureters, and talipes equinovarus.", "completion": "{\"entities\": [{\"text\": \"Potter's facies\", \"type\": \"Disease\"}, {\"text\": \"hypoplastic lungs\", \"type\": \"Disease\"}, {\"text\": \"absent kidneys and ureters\", \"type\": \"Disease\"}, {\"text\": \"talipes equinovarus\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00612", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Her symptoms totally regressed after drug withdrawal and reappeared when acitretin was reintroduced.", "completion": "{\"entities\": [{\"text\": \"acitretin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01949", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After two to seven cycles of chemotherapy, nine patients showed a decrease in tumor size and surrounding edema on contrast - enhanced computerized tomography scans.", "completion": "{\"entities\": [{\"text\": \"tumor\", \"type\": \"Disease\"}, {\"text\": \"edema\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00077", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: While she was weak, 2 - Hz repetitive stimulation revealed a decrement without significant facilitation at rapid rates or after exercise, suggesting postsynaptic neuromuscular blockade.", "completion": "{\"entities\": [{\"text\": \"postsynaptic neuromuscular blockade\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00587", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 01) after nitroglycerin in subjects with no migraine attack but no consistent change was observed in patients with migraine attack.", "completion": "{\"entities\": [{\"text\": \"nitroglycerin\", \"type\": \"Chemical\"}, {\"text\": \"migraine\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02584", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In these patients, the magnitude of proteinuria was assessed on morning urine samples by turbidometric measurement or random urine protein: creatinine ratios, an estimate of grams of proteinuria / day.", "completion": "{\"entities\": [{\"text\": \"proteinuria\", \"type\": \"Disease\"}, {\"text\": \"creatinine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02572", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 40 days in sgk1 (+/+) mice ). In conclusion, gene - targeted mice lacking SGK1 showed blunted volume retention, yet were not protected against renal fibrosis during experimental nephrotic syndrome", "completion": "{\"entities\": [{\"text\": \"volume retention\", \"type\": \"Disease\"}, {\"text\": \"fibrosis\", \"type\": \"Disease\"}, {\"text\": \"nephrotic syndrome\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00929", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Whole body hyperthermia (120 min at 41.", "completion": "{\"entities\": [{\"text\": \"hyperthermia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02751", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: group 3 ). Reduction in GFR was associated with the development of glomerular sclerosis", "completion": "{\"entities\": [{\"text\": \"glomerular sclerosis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04063", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: All of the rats in the saline - treated epileptic control group developed SRS, whereas none of the BMC - treated epileptic animals had seizures in the short term (15 days after transplantation ), regardless of the BMC source.", "completion": "{\"entities\": [{\"text\": \"epileptic\", \"type\": \"Disease\"}, {\"text\": \"SRS\", \"type\": \"Disease\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02577", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Whereas patient 1 showed lesions of up to 1 cm readily detectable on magnetic resonance imaging under prolonged co-trimoxazole", "completion": "{\"entities\": [{\"text\": \"co-trimoxazole\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02933", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Furthermore, transient hemoglobinuria was noted approximately 60 minutes postinjection of WR242511 (3.", "completion": "{\"entities\": [{\"text\": \"hemoglobinuria\", \"type\": \"Disease\"}, {\"text\": \"WR242511\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02814", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 001 ). The EF was 40 %, in the group with MP and 44% in the group with severe MR", "completion": "{\"entities\": [{\"text\": \"MP\", \"type\": \"Disease\"}, {\"text\": \"MR\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02012", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: phentolamine and 10 micrograms.", "completion": "{\"entities\": [{\"text\": \"phentolamine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03441", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: All patients were on a regular transfusion - chelation program maintaining a mean hemoglobin level of 9.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00718", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, OD was significantly higher in all patients with thrombosis (n = 48, 1.", "completion": "{\"entities\": [{\"text\": \"thrombosis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01343", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The relationship between hippocampal acetylcholine release and cholinergic convulsant sensitivity in withdrawal seizure - prone and withdrawal seizure - resistant selected mouse lines.", "completion": "{\"entities\": [{\"text\": \"acetylcholine\", \"type\": \"Chemical\"}, {\"text\": \"seizure\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02305", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Few days later, the patient used another 200 mg ketoconazole tablet, and within an hour experienced a similar clinical picture, which resolved again spontaneously within hours.", "completion": "{\"entities\": [{\"text\": \"ketoconazole\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04034", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The mean age of patients in the 16 probable cases was 57.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03160", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 7 %). According to intention - to - treat, the overall response rate was 71.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04259", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Careful fluid administration and cautious use of titrated doses of ephedrine are advised.", "completion": "{\"entities\": [{\"text\": \"ephedrine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01779", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This low percentage (5 %) of TDFS must be evaluated with respect to the efficacy of ifosfamide in the treatment of mesenchymal tumors", "completion": "{\"entities\": [{\"text\": \"ifosfamide\", \"type\": \"Chemical\"}, {\"text\": \"mesenchymal tumors\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-04640", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 2) of abnormal cardiomyocytes.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04331", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05) and also significantly increased sigmaST (P less than 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04449", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Mitochondrial abnormalities have been associated with several aspects of epileptogenesis, such as energy generation, control of cell death, neurotransmitter synthesis, and free radical (FR) production.", "completion": "{\"entities\": [{\"text\": \"Mitochondrial abnormalities\", \"type\": \"Disease\"}, {\"text\": \"death\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03754", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CI-921 (NSC 343499; 9-[[2-methoxy-4-[(methylsulphonyl)amino]phenyl]amino] -N,5-dimethyl- 4-acridinecarboxamide) is a topoisomerase II poison with high experimental antitumour activity.", "completion": "{\"entities\": [{\"text\": \"CI-921\", \"type\": \"Chemical\"}, {\"text\": \"NSC 343499\", \"type\": \"Chemical\"}, {\"text\": \"9-[[2-methoxy-4-[(methylsulphonyl)amino]phenyl]amino] -N,5-dimethyl- 4-acridinecarboxamide\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00040", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Treatment of Crohn's disease with fusidic acid: an antibiotic with immunosuppressive properties similar to cyclosporin.", "completion": "{\"entities\": [{\"text\": \"Crohn's disease\", \"type\": \"Disease\"}, {\"text\": \"fusidic acid\", \"type\": \"Chemical\"}, {\"text\": \"cyclosporin\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00912", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The recovery of urinary concentrating ability was related to the length of analgesic treatment and the extent of the resulting inner medullary structural damage.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01520", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This calls for attention when ketoconazole is administered to patients with risk factors for acquired long QT syndrome", "completion": "{\"entities\": [{\"text\": \"ketoconazole\", \"type\": \"Chemical\"}, {\"text\": \"long QT syndrome\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01300", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: On the basis that only free drug in the systemic circulation will elicit a pharmacological response target, free concentrations in plasma were selected to mimic the free drug exposures in man.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00121", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Chronic carbamazepine treatment in the rat: efficacy, toxicity, and effect on plasma and tissue folate concentrations.", "completion": "{\"entities\": [{\"text\": \"carbamazepine\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}, {\"text\": \"folate\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03818", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This observation demonstrates that prolonged cholestasis can follow troleandomycin - induced acute hepatitis", "completion": "{\"entities\": [{\"text\": \"cholestasis\", \"type\": \"Disease\"}, {\"text\": \"troleandomycin\", \"type\": \"Chemical\"}, {\"text\": \"hepatitis\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02999", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Clinical evaluations suggested an initial diagnosis of severe thrombocytopenia and haemolysis.", "completion": "{\"entities\": [{\"text\": \"thrombocytopenia\", \"type\": \"Disease\"}, {\"text\": \"haemolysis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01285", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Therefore, three novel sigma receptor ligands with antagonist activity were evaluated in Swiss Webster mice: BD1018 (3S-1-[2-(3,4-dichlorophenyl)ethyl]-1,4-diazabicyclo[4.3.0]nonane ), BD1063 (1-[2-(3,4-dichlorophenyl)ethyl]-4-methylpiperazine ), and LR132 (1R, 2S -(+)- cis - N -[2 -(3, 4 - dichlorophenyl) ethyl ]- 2 -(1 - pyrrolidinyl) cyclohexylamine ). Competition binding assays demonstrated that all three compounds have high affinities for sigma1 receptors.", "completion": "{\"entities\": [{\"text\": \"BD1018\", \"type\": \"Chemical\"}, {\"text\": \"3S-1-[2-(3,4-dichlorophenyl)ethyl]-1,4-diazabicyclo[4.3.0]nonane\", \"type\": \"Chemical\"}, {\"text\": \"BD1063\", \"type\": \"Chemical\"}, {\"text\": \"1-[2-(3,4-dichlorophenyl)ethyl]-4-methylpiperazine\", \"type\": \"Chemical\"}, {\"text\": \"LR132\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-01502", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The effects of short - term raloxifene therapy on fibrinolysis markers: TAFI, tPA, and PAI - 1.", "completion": "{\"entities\": [{\"text\": \"raloxifene\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02619", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In a double - blind 6 - week trial, 458 patients with acute schizophrenia were randomly assigned to fixed - dose treatment with asenapine at 5 mg twice daily (BID ), asenapine at 10 mg BID, placebo, or haloperidol at 4 mg BID (to verify assay sensitivity ). With last observations carried forward (LOCF ), mean Positive and Negative Syndrome Scale total score reductions from baseline to endpoint were significantly greater with asenapine at 5 mg BID (- 16.", "completion": "{\"entities\": [{\"text\": \"schizophrenia\", \"type\": \"Disease\"}, {\"text\": \"asenapine\", \"type\": \"Chemical\"}, {\"text\": \"haloperidol\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03432", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Alterations in hepatocyte TJs were assessed by double - immunolabeling for 7H6 and ZO - 1 using a confocal laser scanning microscope.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03779", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Severe side effects in terms of mental confusion and progressive hyperbilirubinemia, however, point to an enhancement not only of antineoplastic effects but also of toxicity in normal tissues.", "completion": "{\"entities\": [{\"text\": \"confusion\", \"type\": \"Disease\"}, {\"text\": \"hyperbilirubinemia\", \"type\": \"Disease\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00550", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Ticlopidine - induced cholestatic hepatitis.", "completion": "{\"entities\": [{\"text\": \"Ticlopidine\", \"type\": \"Chemical\"}, {\"text\": \"cholestatic hepatitis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00913", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: During the early stages of analgesic treatment, the changes in urinary concentrating ability were reversible, but after prolonged analgesic treatment, maximum urinary concentrating ability failed to recover.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00560", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: Cholestatic hepatitis is a rare adverse effect of ticlopidine that may be immune mediated.", "completion": "{\"entities\": [{\"text\": \"Cholestatic hepatitis\", \"type\": \"Disease\"}, {\"text\": \"ticlopidine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03708", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Results thus far suggest no dose - response effect for paclitaxel", "completion": "{\"entities\": [{\"text\": \"paclitaxel\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01132", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The heparan sulphate specificity of the cuprolinic blue staining was demonstrated by glycosaminoglycan - degrading enzymes, showing that pretreatment of the sections with heparitinase abolished all staining, whereas chondroitinase ABC had no effect.", "completion": "{\"entities\": [{\"text\": \"heparan sulphate\", \"type\": \"Chemical\"}, {\"text\": \"cuprolinic blue\", \"type\": \"Chemical\"}, {\"text\": \"glycosaminoglycan\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00965", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Intracranial aneurysms or arteriovenous malformations were present in 17 of 32 patients studied angiographically or at autopsy; cerebral vasculitis was present in two patients.", "completion": "{\"entities\": [{\"text\": \"Intracranial aneurysms\", \"type\": \"Disease\"}, {\"text\": \"arteriovenous malformations\", \"type\": \"Disease\"}, {\"text\": \"cerebral vasculitis\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00292", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The present results are consistent with the carcinogenicity experiment suggesting that different mechanisms are involved in FANFT carcinogenesis in the bladder and forestomach, and that aspirin' s effect on FANFT in the forestomach is not due to an irritant effect associated with increased cell proliferation.", "completion": "{\"entities\": [{\"text\": \"FANFT\", \"type\": \"Chemical\"}, {\"text\": \"carcinogenesis\", \"type\": \"Disease\"}, {\"text\": \"aspirin\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04561", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Unusual features of the arrhythmia are repetitive group beating, progressive shortening of the R - R interval, progressive widening of the QRS complex with eventual failure of intraventricular conduction, and changes in direction of the QRS axis.", "completion": "{\"entities\": [{\"text\": \"arrhythmia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03240", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: kg (- 1 ). min (- 1 )), increasing significantly to 66.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01061", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 7 %) were identified with toxic hepatitis which could reasonably be attributed to the use of antithyroid agent.", "completion": "{\"entities\": [{\"text\": \"toxic hepatitis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01699", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, the observation that antagonists of the glutamate N-methyl-D-aspartate (NMDA) receptor produce schizophrenic - like symptoms in humans has led to the idea of a dysfunctioning of the glutamatergic system via its NMDA receptor.", "completion": "{\"entities\": [{\"text\": \"glutamate\", \"type\": \"Chemical\"}, {\"text\": \"N-methyl-D-aspartate\", \"type\": \"Chemical\"}, {\"text\": \"NMDA\", \"type\": \"Chemical\"}, {\"text\": \"schizophrenic\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-reassigned-03764", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Six patients developed neuropathy.", "completion": "{\"entities\": [{\"text\": \"neuropathy\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04851", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pyrrolidine dithiocarbamate (PDTC) has a dual mechanism of action as an antioxidant and an inhibitor of the transcription factor kappa - beta.", "completion": "{\"entities\": [{\"text\": \"Pyrrolidine dithiocarbamate\", \"type\": \"Chemical\"}, {\"text\": \"PDTC\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01257", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In male animals, repeated apomorphine treatment induced a gradual development of aggressive behavior as evidenced by the increased intensity of aggressiveness and shortened latency before the first attack toward the opponent.", "completion": "{\"entities\": [{\"text\": \"apomorphine\", \"type\": \"Chemical\"}, {\"text\": \"aggressive behavior\", \"type\": \"Disease\"}, {\"text\": \"aggressiveness\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-reassigned-04212", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Although cortical laminar necrosis", "completion": "{\"entities\": [{\"text\": \"necrosis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02209", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: GSPE + drug exposed tissues exhibited minor residual damage or near total recovery.", "completion": "{\"entities\": [{\"text\": \"GSPE\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00446", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Recent reports indicate that single agent therapy with vinorelbine (VNB) or gemcitabine (GEM) may obtain a response rate of 20 - 30% in elderly patients, with acceptable toxicity and improvement in symptoms and quality of life.", "completion": "{\"entities\": [{\"text\": \"vinorelbine\", \"type\": \"Chemical\"}, {\"text\": \"VNB\", \"type\": \"Chemical\"}, {\"text\": \"gemcitabine\", \"type\": \"Chemical\"}, {\"text\": \"GEM\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-04172", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: All solutions were provided in blinded vials by the hospital pharmacy.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03112", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A paracetamol serum level obtained in one of these patients was not in the toxic range.", "completion": "{\"entities\": [{\"text\": \"paracetamol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03316", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: Renal ACE activity (Hip-His-Leu cleavage by cortical homogenates) was determined by renal biopsy in 27 adult male Wistar rats.", "completion": "{\"entities\": [{\"text\": \"Hip-His-Leu\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-reassigned-03384", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Neuroleptic malignant syndrome and methylphenidate.", "completion": "{\"entities\": [{\"text\": \"Neuroleptic malignant syndrome\", \"type\": \"Disease\"}, {\"text\": \"methylphenidate\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04236", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Instillation was repeated twice during the first week, then weekly during the first month and afterwards monthly for 1 year.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-reassigned-05544", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 03, 95% confidence interval [CI] 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00093", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thus the migraine - inducing effect of nitroglycerin seems to depend on direct stimulation of the habitual site of pain, suggesting that the frontotemporal region is of crucial importance in the development of a migraine crisis.", "completion": "{\"entities\": [{\"text\": \"migraine\", \"type\": \"Disease\"}, {\"text\": \"nitroglycerin\", \"type\": \"Chemical\"}, {\"text\": \"pain\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00613", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: To our knowledge, this is the first case of acitretin - induced dysphonia", "completion": "{\"entities\": [{\"text\": \"acitretin\", \"type\": \"Chemical\"}, {\"text\": \"dysphonia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02836", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSION: This study confirms our previous finding that selegiline in combination with L-dopa is associated with selective orthostatic hypotension.", "completion": "{\"entities\": [{\"text\": \"selegiline\", \"type\": \"Chemical\"}, {\"text\": \"L-dopa\", \"type\": \"Chemical\"}, {\"text\": \"orthostatic hypotension\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01337", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 8 %). CONCLUSION: A 50% reduction in the incidence of akathisia when prochlorperazine was administered by means of 15 - minute intravenous infusion versus a 2 - minute intravenous push was not detected.", "completion": "{\"entities\": [{\"text\": \"akathisia\", \"type\": \"Disease\"}, {\"text\": \"prochlorperazine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02158", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A developmental analysis of clonidine' s effects on cardiac rate and ultrasound production in infant rats.", "completion": "{\"entities\": [{\"text\": \"clonidine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01259", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In conclusion, the present study demonstrates gender differences in the development of the apomorphine - induced aggressive behavior", "completion": "{\"entities\": [{\"text\": \"apomorphine\", \"type\": \"Chemical\"}, {\"text\": \"aggressive behavior\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00425", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These responded to systemic steroids and immunoglobulins.", "completion": "{\"entities\": [{\"text\": \"steroids\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04024", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: They showed significantly more rapid improvement of motor function in the first week following hemorrhage and better memory retention in the passive avoidance test.", "completion": "{\"entities\": [{\"text\": \"hemorrhage\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01411", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 3% of prostate cancer", "completion": "{\"entities\": [{\"text\": \"prostate cancer\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04897", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Due to the interdependence of risk factors in clinical populations, it is difficult to independently examine factors that may influence the development of LIDs.", "completion": "{\"entities\": [{\"text\": \"LIDs\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04221", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 9 %). In conclusion, octreotide induced gall stones are generally small, multiple, and cholesterol rich although, in common with spontaneous gall stone disease, at presentation some patients will have a blocked cystic duct and some gall stones containing calcium", "completion": "{\"entities\": [{\"text\": \"octreotide\", \"type\": \"Chemical\"}, {\"text\": \"gall stones\", \"type\": \"Disease\"}, {\"text\": \"cholesterol\", \"type\": \"Chemical\"}, {\"text\": \"gall stone disease\", \"type\": \"Disease\"}, {\"text\": \"calcium\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-00436", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The present study was undertaken to investigate the effects of TET and FAN on the experimental thrombosis induced by collagen plus epinephrine (EP) in mice, and platelet aggregation and blood coagulation in vitro.", "completion": "{\"entities\": [{\"text\": \"TET\", \"type\": \"Chemical\"}, {\"text\": \"FAN\", \"type\": \"Chemical\"}, {\"text\": \"thrombosis\", \"type\": \"Disease\"}, {\"text\": \"epinephrine\", \"type\": \"Chemical\"}, {\"text\": \"EP\", \"type\": \"Chemical\"}, {\"text\": \"platelet aggregation\", \"type\": \"Disease\"}, {\"text\": \"blood coagulation\", \"type\": \"Disease\"}]}", "n_entities": 7}
{"ref": "bc5cdr-train-00200", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Haloperidol enhanced the rigidity in the A group.", "completion": "{\"entities\": [{\"text\": \"Haloperidol\", \"type\": \"Chemical\"}, {\"text\": \"rigidity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01202", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Apart from the reduction in the patient' s level of consciousness, there were no signs of motor neurone damage or of any of the other known predisposing conditions for hyperkalaemia following the administration of suxamethonium.", "completion": "{\"entities\": [{\"text\": \"hyperkalaemia\", \"type\": \"Disease\"}, {\"text\": \"suxamethonium\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00031", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Corresponding non - lithium pretreated groups were generated.", "completion": "{\"entities\": [{\"text\": \"lithium\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02431", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Levofloxacin, a fluoroquinolone, is one of the most commonly prescribed antibiotics in clinical practice and is effective against Gram - positive, Gram - negative, and atypical bacteria.", "completion": "{\"entities\": [{\"text\": \"Levofloxacin\", \"type\": \"Chemical\"}, {\"text\": \"fluoroquinolone\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02630", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Extrapyramidal symptoms reported as AEs occurred in 15% and 18 %, 34 %, and 10% of the asenapine at 5 and 10 mg BID, haloperidol, and placebo groups, respectively.", "completion": "{\"entities\": [{\"text\": \"Extrapyramidal symptoms\", \"type\": \"Disease\"}, {\"text\": \"asenapine\", \"type\": \"Chemical\"}, {\"text\": \"haloperidol\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04834", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the double blind study with haloperidol, both substances were found to be highly effective in the treatment of psychotic syndromes belonging predominantly to the schizophrenia group.", "completion": "{\"entities\": [{\"text\": \"haloperidol\", \"type\": \"Chemical\"}, {\"text\": \"psychotic syndromes belonging predominantly to the schizophrenia group\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03092", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Partial lesions were made with kainic acid in the interpeduncular nucleus of the ventral midbrain of the rat.", "completion": "{\"entities\": [{\"text\": \"kainic acid\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01139", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0) mg / 24 h after 8 months in contrast to the control animals (0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04832", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Nine patients exhibited mild to moderate extrapyramidal concomitant symptoms; no other side effects were observed.", "completion": "{\"entities\": [{\"text\": \"extrapyramidal concomitant symptoms\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03478", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 6 mM) of [Ca] o did not modify BF; a reduction of ten times (0.", "completion": "{\"entities\": [{\"text\": \"Ca\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01440", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Three time domain indexes of hemodynamic variability were employed: the standard deviation of mean arterial pressure as a measure of blood pressure variability and the standard deviation of beat - to - beat intervals (SDRR) and the root mean square of successive differences in R - wave - to - R - wave intervals as measures of heart rate variability.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03156", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: An objective response was observed in 73.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04067", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The donor - derived GFP (+) cells were rarely found in the brains of transplanted epileptic rats.", "completion": "{\"entities\": [{\"text\": \"epileptic\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03217", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Physicians who prescribe molindone", "completion": "{\"entities\": [{\"text\": \"molindone\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02029", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Seven patients suffering from Parkinson's disease (PD) with severely disabling dyskinesia received low - dose propranolol as an adjunct to the currently used medical treatment.", "completion": "{\"entities\": [{\"text\": \"Parkinson's disease\", \"type\": \"Disease\"}, {\"text\": \"PD\", \"type\": \"Disease\"}, {\"text\": \"dyskinesia\", \"type\": \"Disease\"}, {\"text\": \"propranolol\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03915", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Older reports suggest an objective response rate of 8% when 60 - 120 mg / m2 of cisplatin is administered every 3 - 4 weeks.", "completion": "{\"entities\": [{\"text\": \"cisplatin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02086", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Both plasma pethidine and norpethidine were elevated in the range associated with clinical manifestations of central nervous system excitation.", "completion": "{\"entities\": [{\"text\": \"pethidine\", \"type\": \"Chemical\"}, {\"text\": \"norpethidine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05185", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Further observations and reports will help clarify this adverse effect.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02426", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cells were pretreated with maltolyl p-coumarate, before exposed to amyloid beta peptide(1-42), glutamate or H2O2.", "completion": "{\"entities\": [{\"text\": \"maltolyl p-coumarate\", \"type\": \"Chemical\"}, {\"text\": \"amyloid beta peptide(1-42)\", \"type\": \"Chemical\"}, {\"text\": \"glutamate\", \"type\": \"Chemical\"}, {\"text\": \"H2O2\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00921", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: Urine volume can be reduced by giving lithium once daily and / or by lowering the total daily dose.", "completion": "{\"entities\": [{\"text\": \"lithium\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00492", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In contrast, mood switches were less frequent in patients receiving lithium (15 %, 4 / 26) than in patients not treated with lithium (44 %, 8 / 18; p =. 04 ). The number of previous manic episodes did not affect the probability of switching, whereas a high score on the hyperthymia component of the Semistructured Affective Temperament Interview was associated with a greater risk of switching (p =. 008 ). CONCLUSION: The frequency of mood switching associated with acute antidepressant therapy may be reduced by lithium", "completion": "{\"entities\": [{\"text\": \"lithium\", \"type\": \"Chemical\"}, {\"text\": \"manic\", \"type\": \"Disease\"}, {\"text\": \"antidepressant\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01940", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Effect of polyethylene glycol 400 on adriamycin toxicity in mice.", "completion": "{\"entities\": [{\"text\": \"polyethylene glycol 400\", \"type\": \"Chemical\"}, {\"text\": \"adriamycin\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02690", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The patient' s lipid panel had been maintained with simvastatin for 18 months before the conversion without evidence of hepatotoxicity.", "completion": "{\"entities\": [{\"text\": \"simvastatin\", \"type\": \"Chemical\"}, {\"text\": \"hepatotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01957", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Intrarenal infusion of noradrenaline caused hypertension at doses which did not do so when infused intravenously.", "completion": "{\"entities\": [{\"text\": \"noradrenaline\", \"type\": \"Chemical\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03717", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Myelosuppression was more in patients with hepatic dysfunction.", "completion": "{\"entities\": [{\"text\": \"Myelosuppression\", \"type\": \"Disease\"}, {\"text\": \"hepatic dysfunction\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04345", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: When drugs disappear from the patient: elimination of intravenous medication by hemodiafiltration.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00805", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Prospective studies on ATT - ALF are lacking.", "completion": "{\"entities\": [{\"text\": \"ALF\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03843", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Other possible adverse effects -- such as gastrointestinal disorders, orthostatic hypotension, levodopa - induced psychosis, sleep disturbances or parasomnias, or drug interactions -- also require carefully monitored individual treatment.", "completion": "{\"entities\": [{\"text\": \"gastrointestinal disorders\", \"type\": \"Disease\"}, {\"text\": \"orthostatic hypotension\", \"type\": \"Disease\"}, {\"text\": \"levodopa\", \"type\": \"Chemical\"}, {\"text\": \"psychosis\", \"type\": \"Disease\"}, {\"text\": \"sleep disturbances\", \"type\": \"Disease\"}, {\"text\": \"parasomnias\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-01730", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: of these current models demonstrate multiple OCD - like behaviors.", "completion": "{\"entities\": [{\"text\": \"OCD\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03275", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Systolic blood pressure (SBP) was measured on alternate days using the tail - cuff method.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00903", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The mean duration of action was 3.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00747", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: NIN correlated with blood oxygen level - dependent (BOLD) activity levels in a midpontine site in the posterior basis pontis.", "completion": "{\"entities\": [{\"text\": \"NIN\", \"type\": \"Disease\"}, {\"text\": \"oxygen\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00988", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 8 mm Hg in the HEM and SNP groups, respectively, during hypotension (P less than 0.", "completion": "{\"entities\": [{\"text\": \"HEM\", \"type\": \"Disease\"}, {\"text\": \"SNP\", \"type\": \"Chemical\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04791", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Nuclear factor kappa B (NFkappaB) is a sensor of oxidative stress and participates in memory formation that could be involved in drug toxicity and addiction mechanisms.", "completion": "{\"entities\": [{\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02241", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In independent groups, morphine inhibited the intestinal transit in 48 +/- 4% and 38 +/- 4% after acute and chronic treatment, respectively, suggesting that tolerance did not develop to the constipating effects.", "completion": "{\"entities\": [{\"text\": \"morphine\", \"type\": \"Chemical\"}, {\"text\": \"constipating\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01561", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Hormone therapy users were compared with never users.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03580", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In six of the probable cases the neurological disturbance consisted of an acute reversible encephalopathy usually related to the ingestion of a high dose of clioquinol over a short period.", "completion": "{\"entities\": [{\"text\": \"neurological disturbance\", \"type\": \"Disease\"}, {\"text\": \"encephalopathy\", \"type\": \"Disease\"}, {\"text\": \"clioquinol\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00656", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Serum creatinine values did not change significantly: 1.", "completion": "{\"entities\": [{\"text\": \"creatinine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00570", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Sodium retention occurred on days 2, 3 and 6 after PAN injection.", "completion": "{\"entities\": [{\"text\": \"Sodium\", \"type\": \"Chemical\"}, {\"text\": \"PAN\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01998", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Compared with placebo subjects, alprazolam patients developed more adverse reactions (21% v.", "completion": "{\"entities\": [{\"text\": \"alprazolam\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03925", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Treatment was administered every 3 weeks until disease progression.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01679", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The management options in the ED, as exemplified by four individual case reports, in particular the use of a minimally invasive method of intracorporal epinephrine", "completion": "{\"entities\": [{\"text\": \"epinephrine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04002", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These are nephrotoxic, but SRL seems to act differently displaying only minor nephrotoxic effects, although this question is still open.", "completion": "{\"entities\": [{\"text\": \"nephrotoxic\", \"type\": \"Disease\"}, {\"text\": \"SRL\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00219", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We have reported a case of acute oliguric renal failure with hyperkalemia in a patient with cirrhosis, ascites, and cor pulmonale after indomethacin therapy.", "completion": "{\"entities\": [{\"text\": \"renal failure\", \"type\": \"Disease\"}, {\"text\": \"hyperkalemia\", \"type\": \"Disease\"}, {\"text\": \"cirrhosis\", \"type\": \"Disease\"}, {\"text\": \"ascites\", \"type\": \"Disease\"}, {\"text\": \"cor pulmonale\", \"type\": \"Disease\"}, {\"text\": \"indomethacin\", \"type\": \"Chemical\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-04802", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: v .; 10 - 30 micrograms / mouse i.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04291", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5, 1, 2, 3, and 6 h after injection the subjects were given attention and mnemonic tests.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03806", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 2 receptor compared with the human cloned dopamine D2L receptor.", "completion": "{\"entities\": [{\"text\": \"dopamine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04095", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 mg / dL ); direct bilirubin, 14.", "completion": "{\"entities\": [{\"text\": \"bilirubin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04356", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 011 ). Also the frequency of abnormal electro - diagnostic findings showed similarity between the two groups (G: 7 / 23 = 30.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03469", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Endothelial cell culture supernatants separated by ultrafiltration and ultracentrifugation from cells treated with EPO and IL - 3 significantly reduced thymidine", "completion": "{\"entities\": [{\"text\": \"thymidine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04668", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Almost 36% of patients taking rizatriptan were pain free at 2 h and had no recurrence or need for additional medication within 24 h, compared to 20% of patients on ergotamine / caffeine (p < or = 0.", "completion": "{\"entities\": [{\"text\": \"rizatriptan\", \"type\": \"Chemical\"}, {\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"ergotamine\", \"type\": \"Chemical\"}, {\"text\": \"caffeine\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03492", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In conclusion, reductions in creatinine clearance and renal amphotericin B accumulation after chronic amphotericin B administration were enhanced by salt depletion and attenuated by sodium", "completion": "{\"entities\": [{\"text\": \"creatinine\", \"type\": \"Chemical\"}, {\"text\": \"amphotericin B\", \"type\": \"Chemical\"}, {\"text\": \"sodium\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-05008", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Flestolol: an ultra - short - acting beta - adrenergic blocking agent.", "completion": "{\"entities\": [{\"text\": \"Flestolol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01060", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Four patients (1.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00692", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The residual serum concentrations of oxazepam, temazepam and zopiclone were analysed.", "completion": "{\"entities\": [{\"text\": \"oxazepam\", \"type\": \"Chemical\"}, {\"text\": \"temazepam\", \"type\": \"Chemical\"}, {\"text\": \"zopiclone\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04124", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Patients were divided into three groups: Controls, no CRF or ESRD, n = 748; CRF, sustained serum creatinine > 2.", "completion": "{\"entities\": [{\"text\": \"CRF\", \"type\": \"Disease\"}, {\"text\": \"ESRD\", \"type\": \"Disease\"}, {\"text\": \"creatinine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01766", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: During the six - month follow up, depression was quantified through the Beck and Zung - Conde scales every two months.", "completion": "{\"entities\": [{\"text\": \"depression\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04262", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: To clarify the effects of bromocriptine on prolactinoma cells in vivo, immunohistochemical, ultrastructural and morphometrical analyses were applied to estrogen - induced rat prolactinoma cells 1 h and 6 h after injection of bromocriptine (3 mg / kg of body weight ). One h after treatment, serum prolactin levels decreased markedly.", "completion": "{\"entities\": [{\"text\": \"bromocriptine\", \"type\": \"Chemical\"}, {\"text\": \"prolactinoma\", \"type\": \"Disease\"}, {\"text\": \"estrogen\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04808", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: p .) and dicyclomine (2 mg kg - 1 i.", "completion": "{\"entities\": [{\"text\": \"dicyclomine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00062", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We could not find any previous reports of sulpiride - induced tardive dystonia", "completion": "{\"entities\": [{\"text\": \"sulpiride\", \"type\": \"Chemical\"}, {\"text\": \"tardive dystonia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02169", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Capsaicin 100 micrograms was injected intradermally on the volar forearm followed by an i.", "completion": "{\"entities\": [{\"text\": \"Capsaicin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04270", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: An increase in the volume density of secretory granules and a decrease in the volume densities of rough endoplasmic reticulum and microtubules was determined by morphometric analysis, suggesting that bromocriptine", "completion": "{\"entities\": [{\"text\": \"bromocriptine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00755", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Control rats received corn oil only.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00242", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The effect of long - term timolol treatment on heart size after myocardial infarction was evaluated by X - ray in a double - blind study including 241 patients (placebo 126, timolol 115 ). The follow - up period was 12 months.", "completion": "{\"entities\": [{\"text\": \"timolol\", \"type\": \"Chemical\"}, {\"text\": \"myocardial infarction\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00610", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Recurrent dysphonia and acitretin.", "completion": "{\"entities\": [{\"text\": \"dysphonia\", \"type\": \"Disease\"}, {\"text\": \"acitretin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01491", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Comparison of the patients with or without pseudolithiasis revealed no significant difference with respect to age, sex, duration of the treatment and starvation variables.", "completion": "{\"entities\": [{\"text\": \"pseudolithiasis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01683", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: c .) for 2 days at an interval of 24 h caused a significant (P < 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00432", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Conventional agents are associated with unwanted central nervous system effects, including extrapyramidal symptoms (EPS ), tardive dyskinesia, sedation, and possible impairment of some cognitive measures, as well as cardiac effects, orthostatic hypotension, hepatic changes, anticholinergic side effects, sexual dysfunction, and weight gain.", "completion": "{\"entities\": [{\"text\": \"extrapyramidal symptoms\", \"type\": \"Disease\"}, {\"text\": \"EPS\", \"type\": \"Disease\"}, {\"text\": \"tardive dyskinesia\", \"type\": \"Disease\"}, {\"text\": \"orthostatic hypotension\", \"type\": \"Disease\"}, {\"text\": \"sexual dysfunction\", \"type\": \"Disease\"}, {\"text\": \"weight gain\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-02071", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Up until now, the only factor studied has been the effect of the diameter of the spinal needle on post - operative sensorineural hearing loss.", "completion": "{\"entities\": [{\"text\": \"sensorineural hearing loss\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01065", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Only 2 patients of our retrospective study experienced a mild or severe neutropenia.", "completion": "{\"entities\": [{\"text\": \"neutropenia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03133", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Simvastatin is metabolized by CYP3A4.", "completion": "{\"entities\": [{\"text\": \"Simvastatin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03334", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 01) and glomerular desmin (r = 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01176", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Median number of courses of MFL regimen given was six and the median cumulative dose of mitoxantrone was 68.", "completion": "{\"entities\": [{\"text\": \"MFL regimen\", \"type\": \"Chemical\"}, {\"text\": \"mitoxantrone\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03494", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: OBJECTIVE: This is to present reversible inferior colliculus lesions in metronidazole - induced encephalopathy, to focus on the diffusion - weighted imaging (DWI) and fluid attenuated inversion recovery (FLAIR) imaging.", "completion": "{\"entities\": [{\"text\": \"inferior colliculus lesions\", \"type\": \"Disease\"}, {\"text\": \"metronidazole\", \"type\": \"Chemical\"}, {\"text\": \"encephalopathy\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03768", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These findings suggest that alpha-lipoic acid might reduce the risk of developing peripheral nerve toxicity", "completion": "{\"entities\": [{\"text\": \"alpha-lipoic acid\", \"type\": \"Chemical\"}, {\"text\": \"peripheral nerve toxicity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03047", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the remaining three patients, procainamide was administered orally for treatment of chronic premature ventricular contractions or atrial flutter.", "completion": "{\"entities\": [{\"text\": \"procainamide\", \"type\": \"Chemical\"}, {\"text\": \"premature ventricular contractions\", \"type\": \"Disease\"}, {\"text\": \"atrial flutter\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04494", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: L-arginine uptake was assessed in mononuclear cells incubated with L-arginine (1 to 300 micromol / L ), incorporating 100 nmol / L [3H]-l-arginine for a period of 5 minutes at 37 degrees C.", "completion": "{\"entities\": [{\"text\": \"L-arginine\", \"type\": \"Chemical\"}, {\"text\": \"[3H]-l-arginine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00526", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 3 (95 percent confidence interval, 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03774", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Angiotensin - converting enzyme inhibitors and angiotensin II receptor - blocking drugs hold promise in atrial fibrillation through cardiac remodelling.", "completion": "{\"entities\": [{\"text\": \"Angiotensin\", \"type\": \"Chemical\"}, {\"text\": \"angiotensin II\", \"type\": \"Chemical\"}, {\"text\": \"atrial fibrillation\", \"type\": \"Disease\"}, {\"text\": \"cardiac remodelling\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01136", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 01 for diabetic and control rats, respectively ). Diabetic rats progressively developed albuminuria reaching 40.", "completion": "{\"entities\": [{\"text\": \"diabetic\", \"type\": \"Disease\"}, {\"text\": \"Diabetic\", \"type\": \"Disease\"}, {\"text\": \"albuminuria\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00361", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Coniine, an alkaloid from Conium maculatum (poison hemlock ), has been shown to be teratogenic in livestock.", "completion": "{\"entities\": [{\"text\": \"Coniine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01630", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Possible contributing factors may have been concomitant antidepressant use and unaccustomed physical activity.", "completion": "{\"entities\": [{\"text\": \"antidepressant\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00089", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Source of pain and primitive dysfunction in migraine: an identical site ? Twenty common migraine patients received a one sided frontotemporal application of nitroglycerin (10 patients) or placebo ointment (10 patients) in a double blind study.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"migraine\", \"type\": \"Disease\"}, {\"text\": \"nitroglycerin\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01664", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thalidomide has limited single - agent activity in relapsed or refractory indolent non-Hodgkin lymphomas: a phase II trial of the Cancer and Leukemia Group B.", "completion": "{\"entities\": [{\"text\": \"Thalidomide\", \"type\": \"Chemical\"}, {\"text\": \"non-Hodgkin lymphomas\", \"type\": \"Disease\"}, {\"text\": \"Cancer\", \"type\": \"Disease\"}, {\"text\": \"Leukemia\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04844", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: At the end of study period, serum phenobarbitone and carbamazepine, whole brain malondialdehyde and reduced glutathione levels were estimated.", "completion": "{\"entities\": [{\"text\": \"phenobarbitone\", \"type\": \"Chemical\"}, {\"text\": \"carbamazepine\", \"type\": \"Chemical\"}, {\"text\": \"malondialdehyde\", \"type\": \"Chemical\"}, {\"text\": \"glutathione\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00512", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Results show that cumulative HAART caused mitochondrial CM with elevated LA in AIDS", "completion": "{\"entities\": [{\"text\": \"CM\", \"type\": \"Disease\"}, {\"text\": \"LA\", \"type\": \"Chemical\"}, {\"text\": \"AIDS\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02768", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: One hundred and fourteen children (average age, 5.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03086", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: One patient had focal seizures and transient hemiparesis but recovered completely.", "completion": "{\"entities\": [{\"text\": \"seizures\", \"type\": \"Disease\"}, {\"text\": \"transient hemiparesis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05026", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Enalapril but not nitrendipine reduced blood pressure significantly.", "completion": "{\"entities\": [{\"text\": \"Enalapril\", \"type\": \"Chemical\"}, {\"text\": \"nitrendipine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02640", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The amount of nephrin was reduced in both diseased and normal areas.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03295", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 7 in infarcted rat heart which is six times more than in normal rats.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02576", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Here, we report two cases of severely immunocompromised HIV-infected patients who developed severe intrahepatic cholestasis, and in one patient lesions mimicking liver abscess formation on radiologic exams, during co-trimoxazole treatment for PCP.", "completion": "{\"entities\": [{\"text\": \"HIV-infected\", \"type\": \"Disease\"}, {\"text\": \"intrahepatic cholestasis\", \"type\": \"Disease\"}, {\"text\": \"liver abscess\", \"type\": \"Disease\"}, {\"text\": \"co-trimoxazole\", \"type\": \"Chemical\"}, {\"text\": \"PCP\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-02723", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Effect of converting enzyme inhibition on the course of adriamycin - induced nephropathy.", "completion": "{\"entities\": [{\"text\": \"adriamycin\", \"type\": \"Chemical\"}, {\"text\": \"nephropathy\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04779", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Can angiogenesis be a target of treatment for ribavirin associated hemolytic anemia ? BACKGROUND / AIMS: Recently ribavirin has been found to inhibit angiogenesis and a number of angiogenesis inhibitors such as sunitinib and sorafenib have been found to cause acute hemolysis.", "completion": "{\"entities\": [{\"text\": \"ribavirin\", \"type\": \"Chemical\"}, {\"text\": \"hemolytic anemia\", \"type\": \"Disease\"}, {\"text\": \"sunitinib\", \"type\": \"Chemical\"}, {\"text\": \"sorafenib\", \"type\": \"Chemical\"}, {\"text\": \"hemolysis\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-02592", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Proteinuria may improve, but does not resolve, when sirolimus", "completion": "{\"entities\": [{\"text\": \"Proteinuria\", \"type\": \"Disease\"}, {\"text\": \"sirolimus\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02626", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0) than placebo (- 14.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03973", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Unlike general toxicity data, their prenatal toxic effects were not extensively studied before.", "completion": "{\"entities\": [{\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03795", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Metabolic studies suggested a block in the kynurenine pathway of tryptophan metabolism.", "completion": "{\"entities\": [{\"text\": \"kynurenine\", \"type\": \"Chemical\"}, {\"text\": \"tryptophan\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01494", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Evaluation of the anticocaine monoclonal antibody GNC92H2 as an immunotherapy for cocaine overdose.", "completion": "{\"entities\": [{\"text\": \"GNC92H2\", \"type\": \"Chemical\"}, {\"text\": \"cocaine overdose\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04544", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Acute cocaine - induced seizures: differential sensitivity of six inbred mouse strains.", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04868", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Nine hundred one patients were randomized to treatment, 447 who received the lozenge and 454 who received the gum (safety population ). The majority were women (52.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03233", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In all clones with combined immune escape and LAM resistance mutations, the nucleotide analogues adefovir and tenofovir", "completion": "{\"entities\": [{\"text\": \"LAM\", \"type\": \"Chemical\"}, {\"text\": \"nucleotide\", \"type\": \"Chemical\"}, {\"text\": \"adefovir\", \"type\": \"Chemical\"}, {\"text\": \"tenofovir\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01624", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Acute myocarditis associated with clozapine.", "completion": "{\"entities\": [{\"text\": \"myocarditis\", \"type\": \"Disease\"}, {\"text\": \"clozapine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02183", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The last decade has seen the emergence of tacrolimus as a potent immunosuppressive agent with mechanisms of action virtually identical to those of cyclosporine.", "completion": "{\"entities\": [{\"text\": \"tacrolimus\", \"type\": \"Chemical\"}, {\"text\": \"cyclosporine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00580", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Blood was collected from the antecubital vein four times: 60 min before and after the nitroglycerin application, and 60 and 120 min after the beginning of the migraine attack (mean 344 and 404 min; 12 subjects ). In those subjects who had no migraine attack (11 subjects) a similar time schedule was used.", "completion": "{\"entities\": [{\"text\": \"nitroglycerin\", \"type\": \"Chemical\"}, {\"text\": \"migraine\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02066", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Autoantibodies against P450 2E1 or P58, previously associated with halothane hepatitis, were detected in the serum of five affected workers.", "completion": "{\"entities\": [{\"text\": \"halothane hepatitis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03324", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Baseline renal ACE positively correlated with the relative rise in proteinuria after adriamycin (r = 0.", "completion": "{\"entities\": [{\"text\": \"proteinuria\", \"type\": \"Disease\"}, {\"text\": \"adriamycin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04756", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Omeprazole is the first drug designed to block the final step in the acid secretory process within the parietal cell.", "completion": "{\"entities\": [{\"text\": \"Omeprazole\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02553", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The amount of daily urinary protein decreased from 15.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03386", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We also carried out oral and parenteral challenges with other corticosteroids and found intolerance to some of them.", "completion": "{\"entities\": [{\"text\": \"corticosteroids\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01902", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A dose of 50 mg / kg is recommended in those without audiogram abnormalities.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03314", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This raises the hypothesis that individual differences in renal ACE activity are involved in renal susceptibility to inflicted damage.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02777", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Blood pressure and heart rate remained stable.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01625", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: OBJECTIVE: A case of acute myocarditis associated with the commencement of clozapine is described, highlighting the onset, course and possible contributing factors.", "completion": "{\"entities\": [{\"text\": \"myocarditis\", \"type\": \"Disease\"}, {\"text\": \"clozapine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04135", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Overall survival from the time of OLTX was not significantly different among groups, but by year 13, the survival of the patients who had ESRD was only 28.", "completion": "{\"entities\": [{\"text\": \"ESRD\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04436", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Use of chromosome substitution strains to identify seizure susceptibility loci in mice.", "completion": "{\"entities\": [{\"text\": \"seizure\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01396", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: The mean hemoglobin (Hb) levels were significantly declined in all patients from baseline of 14.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02860", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This report presents the clinical, laboratory, and light and electron microscopic observations on a patient with chronic active (aggressive) hepatitis caused by the administration of propylthiouracil.", "completion": "{\"entities\": [{\"text\": \"chronic active (aggressive) hepatitis\", \"type\": \"Disease\"}, {\"text\": \"propylthiouracil\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04435", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Furthermore, our data suggest that TR (-) rats are an interesting tool to study consequences of overexpression of Pgp in the BBB on access of drugs in the brain, without the need of inducing seizures", "completion": "{\"entities\": [{\"text\": \"seizures\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02711", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Eating disorders and the associated behavioural problems and drug abuse are uncommon in pregnancy.", "completion": "{\"entities\": [{\"text\": \"Eating disorders\", \"type\": \"Disease\"}, {\"text\": \"drug abuse\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01745", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Infusions of epinephrine (4 mug per kilogram per minute for 6 hours) increased radiocalcium uptakes into intact myocardium and each of its subcellular components with the mitochondrial fraction showing the most consistent changes when compared to saline - infused control animals (4, 957 vs.", "completion": "{\"entities\": [{\"text\": \"epinephrine\", \"type\": \"Chemical\"}, {\"text\": \"radiocalcium\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02810", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Mild hypoxia (SO2 < 90 %) was the most common event (11 patients ); 3 patients (2 %) presented transient hypoxia due to upper airway obstruction by probe introduction and 8 (5.", "completion": "{\"entities\": [{\"text\": \"hypoxia\", \"type\": \"Disease\"}, {\"text\": \"airway obstruction\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03911", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In this report we describe the case of a 37 - year - old white woman with Ebstein's anomaly, who developed a rare syndrome called platypnea-orthodeoxia, characterized by massive right - to - left interatrial shunting with transient profound hypoxia and cyanosis.", "completion": "{\"entities\": [{\"text\": \"Ebstein's anomaly\", \"type\": \"Disease\"}, {\"text\": \"platypnea-orthodeoxia\", \"type\": \"Disease\"}, {\"text\": \"hypoxia\", \"type\": \"Disease\"}, {\"text\": \"cyanosis\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02915", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Nephrolithiasis is a complication of acetazolamide", "completion": "{\"entities\": [{\"text\": \"Nephrolithiasis\", \"type\": \"Disease\"}, {\"text\": \"acetazolamide\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04443", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: B6 mice were resistant to seizures and slower to reach stages compared to A / J mice.", "completion": "{\"entities\": [{\"text\": \"seizures\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02759", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: in 11 patients, mutations were found in the BCHE gene, the K - variant being the most frequent.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01932", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Effects of training on the extent of experimental myocardial infarction in aging rats.", "completion": "{\"entities\": [{\"text\": \"myocardial infarction\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04919", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Results presented here show that the differential sensitivities of BS and BR lines to beta-CCM can be extended to diazepam, picrotoxin, and pentylenetetrazol, suggesting a genetic selection of a general sensitivity and resistance to several ligands of the GABA", "completion": "{\"entities\": [{\"text\": \"beta-CCM\", \"type\": \"Chemical\"}, {\"text\": \"diazepam\", \"type\": \"Chemical\"}, {\"text\": \"picrotoxin\", \"type\": \"Chemical\"}, {\"text\": \"pentylenetetrazol\", \"type\": \"Chemical\"}, {\"text\": \"GABA\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-04945", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Testosterone was less than 3 ng ./ ml.", "completion": "{\"entities\": [{\"text\": \"Testosterone\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04613", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Effects of aminophylline on the threshold for initiating ventricular fibrillation during respiratory failure.", "completion": "{\"entities\": [{\"text\": \"aminophylline\", \"type\": \"Chemical\"}, {\"text\": \"ventricular fibrillation\", \"type\": \"Disease\"}, {\"text\": \"respiratory failure\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04692", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: All patients had some response to the combined therapy and five of the seven went into complete remission after one or two courses of AraG / VP / CPM.", "completion": "{\"entities\": [{\"text\": \"AraG\", \"type\": \"Chemical\"}, {\"text\": \"VP\", \"type\": \"Chemical\"}, {\"text\": \"CPM\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02361", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This potential side - effect, though very rare, represents one more reason to be very restrictive in the use of methylphenidate", "completion": "{\"entities\": [{\"text\": \"methylphenidate\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02589", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Proteinuria correlated most strongly with sirolimus therapy when compared to other demographic and clinical variables.", "completion": "{\"entities\": [{\"text\": \"Proteinuria\", \"type\": \"Disease\"}, {\"text\": \"sirolimus\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03882", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: o .), while apomorphine (1.", "completion": "{\"entities\": [{\"text\": \"apomorphine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03016", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We report the case of a patient with amoxicillin-clavulanic acid - induced hepatitis with histologic multiple granulomas.", "completion": "{\"entities\": [{\"text\": \"amoxicillin-clavulanic acid\", \"type\": \"Chemical\"}, {\"text\": \"hepatitis\", \"type\": \"Disease\"}, {\"text\": \"granulomas\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03433", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In control rats, immunostaining for 7H6 and ZO - 1 colocalized to outline bile canaliculi in a continuous fashion.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03503", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: infusions of morphine and regional analgesia by extradural block.", "completion": "{\"entities\": [{\"text\": \"morphine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01022", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Possible teratogenicity of sulphasalazine.", "completion": "{\"entities\": [{\"text\": \"sulphasalazine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04120", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: The calcineurin inhibitors cyclosporine and tacrolimus are both known to be nephrotoxic.", "completion": "{\"entities\": [{\"text\": \"cyclosporine\", \"type\": \"Chemical\"}, {\"text\": \"tacrolimus\", \"type\": \"Chemical\"}, {\"text\": \"nephrotoxic\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00491", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The incidence of mood switches seemed not to differ between patients receiving an anticonvulsant and those receiving no mood stabilizer.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01489", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Fifty children who were given ceftriaxone were evaluated by serial abdominal sonograms.", "completion": "{\"entities\": [{\"text\": \"ceftriaxone\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00452", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: One hundred sixty - five courses were administered, with a median of 3.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03050", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In two patients, the arrhythmia degenerated into irreversible ventricular fibrillation and both patients died.", "completion": "{\"entities\": [{\"text\": \"arrhythmia\", \"type\": \"Disease\"}, {\"text\": \"ventricular fibrillation\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01738", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Late recovery of renal function in a woman with the hemolytic uremic syndrome.", "completion": "{\"entities\": [{\"text\": \"hemolytic uremic syndrome\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02639", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: By day 2, some patchy foot process effacement, but no proteinuria, appeared.", "completion": "{\"entities\": [{\"text\": \"proteinuria\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04478", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Nested within the cohort, a matched case - control study was performed to estimate the association between cyclophosphamide and bladder cancer using odds ratios (ORs) as relative risk.", "completion": "{\"entities\": [{\"text\": \"cyclophosphamide\", \"type\": \"Chemical\"}, {\"text\": \"bladder cancer\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02081", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Prospective multicentre studies with a large population and a long follow - up should be performed in order to evaluate the incidence of this unusual side effect.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03147", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A grade 2 or 3 infection occurred in 16% of patients, but no toxic deaths occurred.", "completion": "{\"entities\": [{\"text\": \"infection\", \"type\": \"Disease\"}, {\"text\": \"deaths\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02275", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Rats received subcutaneous injections of 17beta-estradiol (2 microg / rat) or oil once daily for four consecutive days.", "completion": "{\"entities\": [{\"text\": \"17beta-estradiol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01099", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A large group of patients with suspected allergic reactions to beta-lactam antibiotics was evaluated.", "completion": "{\"entities\": [{\"text\": \"allergic reactions\", \"type\": \"Disease\"}, {\"text\": \"beta-lactam\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02942", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Neuroplasticity of the adult primate auditory cortex following cochlear hearing loss.", "completion": "{\"entities\": [{\"text\": \"hearing loss\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04358", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Attentional modulation of perceived pain intensity in capsaicin - induced secondary hyperalgesia.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"capsaicin\", \"type\": \"Chemical\"}, {\"text\": \"hyperalgesia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-05177", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Visual hallucinations associated with zonisamide.", "completion": "{\"entities\": [{\"text\": \"Visual hallucinations\", \"type\": \"Disease\"}, {\"text\": \"zonisamide\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01735", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: This is the first demonstration of multiple symptoms consistent with an OCD - like profile in animals.", "completion": "{\"entities\": [{\"text\": \"OCD\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04496", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Deep forearm venous samples were collected for determination of L-arginine extraction.", "completion": "{\"entities\": [{\"text\": \"L-arginine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00966", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cerebral infarction occurred in 10 patients (22 %), intracerebral hemorrhage in 22 (49 %), and subarachnoid hemorrhage in 13 (29 %). These data indicate that (1) the apparent incidence of stroke related to cocaine use is increasing ;(2) cocaine - associated stroke occurs primarily in young adults ;(3) stroke may follow any route of cocaine administration ;(4) stroke after cocaine use is frequently associated with intracranial aneurysms and arteriovenous malformations; and (5) in cocaine - associated stroke, the frequency of intracranial hemorrhage exceeds that of cerebral infarction", "completion": "{\"entities\": [{\"text\": \"Cerebral infarction\", \"type\": \"Disease\"}, {\"text\": \"intracerebral hemorrhage\", \"type\": \"Disease\"}, {\"text\": \"subarachnoid hemorrhage\", \"type\": \"Disease\"}, {\"text\": \"stroke\", \"type\": \"Disease\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"intracranial aneurysms\", \"type\": \"Disease\"}, {\"text\": \"arteriovenous malformations\", \"type\": \"Disease\"}, {\"text\": \"intracranial hemorrhage\", \"type\": \"Disease\"}, {\"text\": \"cerebral infarction\", \"type\": \"Disease\"}]}", "n_entities": 9}
{"ref": "bc5cdr-train-03001", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Despite pharmacological and supportive interventions, laboratory parameters worsened and the patient died 17 hours after admission.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04382", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In addition, PD female rats showed increased (3) H - MK-801 binding in the striatum and hippocampus, but not in the cortex.", "completion": "{\"entities\": [{\"text\": \"H\", \"type\": \"Chemical\"}, {\"text\": \"MK-801\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01448", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cardioprotective effect of tincture of Crataegus on isoproterenol - induced myocardial infarction in rats.", "completion": "{\"entities\": [{\"text\": \"tincture of Crataegus\", \"type\": \"Chemical\"}, {\"text\": \"isoproterenol\", \"type\": \"Chemical\"}, {\"text\": \"myocardial infarction\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-reassigned-04534", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Relevant non - indexed journals and conference abstracts were also searched.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00581", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Plasma CGRP concentration increased significantly (P < 0.", "completion": "{\"entities\": [{\"text\": \"CGRP\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02337", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Recurrent acute interstitial nephritis induced by azithromycin.", "completion": "{\"entities\": [{\"text\": \"interstitial nephritis\", \"type\": \"Disease\"}, {\"text\": \"azithromycin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04731", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: The results of this paper confirm that inhibition of bradykinin receptors and inducible NO synthase but not neuronal NO synthase activity reduces diabetic hyperalgesia.", "completion": "{\"entities\": [{\"text\": \"bradykinin\", \"type\": \"Chemical\"}, {\"text\": \"NO\", \"type\": \"Chemical\"}, {\"text\": \"diabetic hyperalgesia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01329", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 7 %; 95% confidence interval [CI ]- 24.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01990", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Safety and side - effects of alprazolam.", "completion": "{\"entities\": [{\"text\": \"alprazolam\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00112", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The amount of fibrin in the kidneys was also considerably lower than in animals which received thrombin and AMCA alone.", "completion": "{\"entities\": [{\"text\": \"AMCA\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03107", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: dP / dtejc outcome was combined with the ECG results, giving an ECG - enhanced value, and compared to ECG alone.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03356", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The results of this study suggest that the blockade of mGluR5 by MPEP may protect dopaminergic neurones against methamphetamine - induced toxicity.", "completion": "{\"entities\": [{\"text\": \"MPEP\", \"type\": \"Chemical\"}, {\"text\": \"methamphetamine\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00111", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Renal damage as reflected by an increase in serum urea and in kidney weight was prevented by Captopril.", "completion": "{\"entities\": [{\"text\": \"Renal damage\", \"type\": \"Disease\"}, {\"text\": \"urea\", \"type\": \"Chemical\"}, {\"text\": \"Captopril\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01856", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Epicardial coronary collateral vessels were demonstrated in all four patients; a coronary\" steal\" phenomenon may be the mechanism of the dipyridamole - induced ischemia", "completion": "{\"entities\": [{\"text\": \"dipyridamole\", \"type\": \"Chemical\"}, {\"text\": \"ischemia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05123", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Twelve (24 %) of them were evaluated as severe hepatitis.", "completion": "{\"entities\": [{\"text\": \"hepatitis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04302", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Whereas cocaine - induced seizures were best characterized as brief, generalized, and tonic and resulted in death, those induced by BE were prolonged, often multiple and mixed in type, and rarely resulted in death.", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}, {\"text\": \"death\", \"type\": \"Disease\"}, {\"text\": \"BE\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-05038", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 17 10 (- 3) mm2) but lower in the enalapril - treated group (11.", "completion": "{\"entities\": [{\"text\": \"enalapril\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03205", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In previous experiments we found that decreases in food intake were induced by local administration of calcitonin into several hypothalamic sites and into the nucleus accumbens.", "completion": "{\"entities\": [{\"text\": \"calcitonin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-reassigned-03554", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5; 95% confidence interval, 1.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-05166", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These results indicate that early changes in glutamate", "completion": "{\"entities\": [{\"text\": \"glutamate\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04601", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 3) before this study with 27 to 532 mg / m2 of doxorubicin (mean 196) were compared with echocardiographic data from 12 normal age - matched control subjects.", "completion": "{\"entities\": [{\"text\": \"doxorubicin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01462", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: During a mean follow - up of 3.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02688", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, hepatotoxic events have not been widely published with ezetimibe or the combination agent simvastatin-ezetimibe.", "completion": "{\"entities\": [{\"text\": \"hepatotoxic\", \"type\": \"Disease\"}, {\"text\": \"ezetimibe\", \"type\": \"Chemical\"}, {\"text\": \"simvastatin-ezetimibe\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03930", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Seven different life - threatening toxicities were observed in patients while receiving treatment.", "completion": "{\"entities\": [{\"text\": \"toxicities\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04923", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A slow bolus of subhypnotic doses of ketamine (0.", "completion": "{\"entities\": [{\"text\": \"ketamine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00124", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A rat model was developed to examine the effects of chronic CBZ treatment on folate concentrations in the rat.", "completion": "{\"entities\": [{\"text\": \"CBZ\", \"type\": \"Chemical\"}, {\"text\": \"folate\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03080", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Leucovorin rescue was initiated 12 hours after the end of the infusion with a loading dose of 200 mg / m2 followed by 12 mg / m2 every three hours for six doses and then every six hours until the plasma methotrexate level decreased to less than 1 X 10 (- 7) mol / L.", "completion": "{\"entities\": [{\"text\": \"Leucovorin\", \"type\": \"Chemical\"}, {\"text\": \"methotrexate\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01837", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Causes of death, with special reference to cerebral haemorrhage, among 240 patients with pathologically verified Parkinson's disease were investigated using the Annuals of the Pathological Autopsy Cases in Japan from 1981 to 1985.", "completion": "{\"entities\": [{\"text\": \"death\", \"type\": \"Disease\"}, {\"text\": \"cerebral haemorrhage\", \"type\": \"Disease\"}, {\"text\": \"Parkinson's disease\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04306", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Protection against amphetamine - induced neurotoxicity toward striatal dopamine neurons in rodents by LY274614, an excitatory amino acid antagonist.", "completion": "{\"entities\": [{\"text\": \"amphetamine\", \"type\": \"Chemical\"}, {\"text\": \"neurotoxicity\", \"type\": \"Disease\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}, {\"text\": \"LY274614\", \"type\": \"Chemical\"}, {\"text\": \"amino acid\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-01309", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We report on two fatal cases of accidental intrathecal vincristine instillation in a 5 - year old girl with recurrent acute lymphoblastic leucemia and a 57 - year old man with lymphoblastic lymphoma.", "completion": "{\"entities\": [{\"text\": \"vincristine\", \"type\": \"Chemical\"}, {\"text\": \"acute lymphoblastic leucemia\", \"type\": \"Disease\"}, {\"text\": \"lymphoblastic lymphoma\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01131", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Morphometric analysis at the ultrastructural level was performed using a computerized image processor.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03515", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Magnetic resonance volumetry of the cerebellum in epileptic patients after phenytoin overdosages.", "completion": "{\"entities\": [{\"text\": \"epileptic\", \"type\": \"Disease\"}, {\"text\": \"phenytoin\", \"type\": \"Chemical\"}, {\"text\": \"overdosages\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03994", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: They offer protection against seizures in a range of models and seem to inhibit certain stages of drug dependence in preclinical assessments.", "completion": "{\"entities\": [{\"text\": \"seizures\", \"type\": \"Disease\"}, {\"text\": \"drug dependence\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03539", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Histology was performed in DOX - rats at 6 and 9 weeks after the last DOX dose and in all controls.", "completion": "{\"entities\": [{\"text\": \"DOX\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04068", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In conclusion, treatment with BMCs can prevent the development of chronic seizures, reduce neuronal loss", "completion": "{\"entities\": [{\"text\": \"seizures\", \"type\": \"Disease\"}, {\"text\": \"neuronal loss\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03787", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We conclude that the administration of high doses of cefonicid or cefazedone to dogs can induce hematotoxicity similar to the cephalosporin - induced blood dyscrasias", "completion": "{\"entities\": [{\"text\": \"cefonicid\", \"type\": \"Chemical\"}, {\"text\": \"cefazedone\", \"type\": \"Chemical\"}, {\"text\": \"hematotoxicity\", \"type\": \"Disease\"}, {\"text\": \"cephalosporin\", \"type\": \"Chemical\"}, {\"text\": \"blood dyscrasias\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-02058", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: QRS without preexcitation, caused by junctional escape beats after verapamil or unidirectional antegrade block of accessory pathway after catheter ablation, established frequent AVRT", "completion": "{\"entities\": [{\"text\": \"verapamil\", \"type\": \"Chemical\"}, {\"text\": \"AVRT\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04507", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Brain MR studies, including DW imaging, were prospectively performed in 14 organ transplant patients receiving tacrolimus who developed neurologic complications.", "completion": "{\"entities\": [{\"text\": \"tacrolimus\", \"type\": \"Chemical\"}, {\"text\": \"neurologic complications\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03390", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: To our knowledge, this is the first report of a pseudo - allergy caused by paramethasone", "completion": "{\"entities\": [{\"text\": \"allergy\", \"type\": \"Disease\"}, {\"text\": \"paramethasone\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01173", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Most of these patients had more than two metastatic sites, with lung metastasis predominant.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04148", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Two hundred sixty - five patients were included in this analysis (n = 92, 93, and 80 for placebo, low dose, and high dose, respectively ). Nimodipine treatment resulted in a statistically significant reduction in systolic BP (SBP) and diastolic BP (DBP) from baseline compared with placebo during the first few days.", "completion": "{\"entities\": [{\"text\": \"Nimodipine\", \"type\": \"Chemical\"}, {\"text\": \"reduction in systolic BP\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04669", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 001 ). Rizatriptan was also superior to ergotamine / caffeine in the proportions of patients with no nausea, vomiting, phonophobia or photophobia and for patients with normal function 2 h after drug intake (p < or = 0.", "completion": "{\"entities\": [{\"text\": \"Rizatriptan\", \"type\": \"Chemical\"}, {\"text\": \"ergotamine\", \"type\": \"Chemical\"}, {\"text\": \"caffeine\", \"type\": \"Chemical\"}, {\"text\": \"nausea\", \"type\": \"Disease\"}, {\"text\": \"vomiting\", \"type\": \"Disease\"}, {\"text\": \"phonophobia\", \"type\": \"Disease\"}, {\"text\": \"photophobia\", \"type\": \"Disease\"}]}", "n_entities": 7}
{"ref": "bc5cdr-train-04468", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We found that the most - frequent cause of thrombotic microangiopathy was drug related, secondary mainly to cyclosporine.", "completion": "{\"entities\": [{\"text\": \"thrombotic microangiopathy\", \"type\": \"Disease\"}, {\"text\": \"cyclosporine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03972", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: Cyclooxygenase (COX) inhibitors are one of the most often ingested drugs during pregnancy.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04843", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Passive avoidance paradigm and elevated plus maze test were used to assess cognitive function.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04650", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Rizatriptan is a selective 5-HT (1B / 1D) receptor agonist with rapid oral absorption and early onset of action in the acute treatment of migraine.", "completion": "{\"entities\": [{\"text\": \"Rizatriptan\", \"type\": \"Chemical\"}, {\"text\": \"5-HT\", \"type\": \"Chemical\"}, {\"text\": \"migraine\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00007", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Lidocaine - induced cardiac asystole.", "completion": "{\"entities\": [{\"text\": \"Lidocaine\", \"type\": \"Chemical\"}, {\"text\": \"cardiac asystole\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01577", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The acute renal dysfunction associated with sirolimus (such as in delayed graft function) may be due to suppression of compensatory renal cell proliferation and survival / repair processes.", "completion": "{\"entities\": [{\"text\": \"acute renal dysfunction\", \"type\": \"Disease\"}, {\"text\": \"sirolimus\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-01275", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: DRC for HR (p less than 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00220", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Prompt restoration of renal function followed drug withdrawal, while re - exposure to a single dose of indomethacin caused recurrence of acute reversible oliguria.", "completion": "{\"entities\": [{\"text\": \"indomethacin\", \"type\": \"Chemical\"}, {\"text\": \"oliguria\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04887", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 8 ), and headache (8.", "completion": "{\"entities\": [{\"text\": \"headache\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03039", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The gamma-aminobutyric acid - transmitted thalamocortical circuitry accounts for a major part of the underlying neurophysiology of the absence epilepsy.", "completion": "{\"entities\": [{\"text\": \"gamma-aminobutyric acid\", \"type\": \"Chemical\"}, {\"text\": \"absence epilepsy\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05183", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The only recent change in their treatment was the introduction or increased dosage of zonisamide.", "completion": "{\"entities\": [{\"text\": \"zonisamide\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02779", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: Ketamine reliably, safely, and quickly provided adequate sedation to effectively facilitate the reduction of children' s fractures in the emergency department at our institution.", "completion": "{\"entities\": [{\"text\": \"Ketamine\", \"type\": \"Chemical\"}, {\"text\": \"fractures\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00354", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Her medical history included coronary artery disease with previous myocardial infarctions, hypertension, and diabetes mellitus.", "completion": "{\"entities\": [{\"text\": \"coronary artery disease\", \"type\": \"Disease\"}, {\"text\": \"myocardial infarctions\", \"type\": \"Disease\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}, {\"text\": \"diabetes mellitus\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04770", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Only minor changes in CD4 + lymphocyte subset count were observed in AIDS patients, although a more significant rise occurred in those with earlier stages of disease.", "completion": "{\"entities\": [{\"text\": \"AIDS\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03908", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Such effects of THP were reversed by RAMH indicating the involvement of histamine H (3 )- receptors.", "completion": "{\"entities\": [{\"text\": \"THP\", \"type\": \"Chemical\"}, {\"text\": \"RAMH\", \"type\": \"Chemical\"}, {\"text\": \"histamine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01266", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Animal studies suggest that incontinence secondary to serotonergic antidepressants", "completion": "{\"entities\": [{\"text\": \"incontinence\", \"type\": \"Disease\"}, {\"text\": \"serotonergic antidepressants\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02294", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Delirium was diagnosed in 14 (10.", "completion": "{\"entities\": [{\"text\": \"Delirium\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04275", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This view supports the contention that the liver and muscle are independent sites of prednisolone", "completion": "{\"entities\": [{\"text\": \"prednisolone\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03923", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After completion of the amifostine infusion, cisplatin 120 mg / m2 was administered over 30 minutes.", "completion": "{\"entities\": [{\"text\": \"amifostine\", \"type\": \"Chemical\"}, {\"text\": \"cisplatin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02944", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In A1 of macaque monkeys, low frequencies are represented rostrolaterally and high frequencies are represented caudomedially.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-05173", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Rats were treated with the vehicle (2 mL / kg of distilled water and 5% w / v cellulose, 10 days ), gum Arabic (2 mL / kg of a 10% w / v aqueous suspension of gum Arabic powder, orally for 10 days ), or gum Arabic concomitantly with GM (80mg / kg / day intramuscularly, during the last six days of the treatment period ). Nephrotoxicity was assessed by measuring the concentrations of creatinine and urea in the plasma and reduced glutathione (GSH) in the kidney cortex, and by light microscopic examination of kidney sections.", "completion": "{\"entities\": [{\"text\": \"gum Arabic\", \"type\": \"Chemical\"}, {\"text\": \"GM\", \"type\": \"Chemical\"}, {\"text\": \"Nephrotoxicity\", \"type\": \"Disease\"}, {\"text\": \"creatinine\", \"type\": \"Chemical\"}, {\"text\": \"urea\", \"type\": \"Chemical\"}, {\"text\": \"glutathione\", \"type\": \"Chemical\"}, {\"text\": \"GSH\", \"type\": \"Chemical\"}]}", "n_entities": 7}
{"ref": "bc5cdr-train-02080", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Sensation in this area returned to normal over the following 2 weeks.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03544", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In 7 of the 18 rats, degeneration and myocyte vacuolisation were found.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01070", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Seventy - five human immunodeficiency virus (HIV)-infected patients with CD4 + cell counts < 500 / mm3 were randomized to receive either ZDV (500 mg daily) alone (group I, n = 38) or in combination with folinic acid (15 mg daily) and intramascular vitamin B12 (1000 micrograms monthly )(group II, n = 37 ). Finally, 15 patients were excluded from the study (noncompliance 14, death 1 ); thus, 60 patients (31 in group I and 29 in group II) were eligible for analysis.", "completion": "{\"entities\": [{\"text\": \"human immunodeficiency virus (HIV)-infected\", \"type\": \"Disease\"}, {\"text\": \"ZDV\", \"type\": \"Chemical\"}, {\"text\": \"folinic acid\", \"type\": \"Chemical\"}, {\"text\": \"vitamin B12\", \"type\": \"Chemical\"}, {\"text\": \"death\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-reassigned-01118", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: All cases of delayed anemia", "completion": "{\"entities\": [{\"text\": \"anemia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01513", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 33 ). CONCLUSION: We suggest that the increased risk of venous thromboembolism due to raloxifene", "completion": "{\"entities\": [{\"text\": \"venous thromboembolism\", \"type\": \"Disease\"}, {\"text\": \"raloxifene\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03561", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Bone pain after transplantation is a frequent complication that can be caused by several diseases.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01555", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSION: Complications associated with epidural steroid injections are rare.", "completion": "{\"entities\": [{\"text\": \"steroid\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00533", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 9 (95 percent confidence interval, 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04393", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Hyperprolactinemia can reduce fertility and libido.", "completion": "{\"entities\": [{\"text\": \"Hyperprolactinemia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05050", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In 24 patients with this complication, the marked slowing of motor nerve conduction velocity and the electromyographic changes imply mainly a demyelinating disorder.", "completion": "{\"entities\": [{\"text\": \"demyelinating disorder\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03520", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In addition, we performed a high - resolution 3D gradient echo, T1 - weighted sequences at a 1 - mm slice thickness.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02835", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Stopping selegiline also significantly reduced the supine systolic and diastolic blood pressures consistent with a previously undescribed supine pressor action.", "completion": "{\"entities\": [{\"text\": \"selegiline\", \"type\": \"Chemical\"}, {\"text\": \"reduced the supine systolic and diastolic blood pressures\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01341", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Bone marrow recovery and peripheral blood recovery were complete 1 month and 3 months, respectively, after treatment, and blood transfusion or other therapies were not necessary in a follow - up period of more than 2 years.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01858", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Nitroprusside - induced hypotension evokes ACTH secretion which is primarily mediated by enhanced secretion of immunoreactive corticotropin - releasing factor (irCRF) into the hypophysial - portal circulation.", "completion": "{\"entities\": [{\"text\": \"Nitroprusside\", \"type\": \"Chemical\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04467", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Other causes include drug - related (cyclosporine, tacrolimus) toxicity, procoagulant status, and antibody - mediated rejection.", "completion": "{\"entities\": [{\"text\": \"cyclosporine\", \"type\": \"Chemical\"}, {\"text\": \"tacrolimus\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-05165", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Importantly, a decrease in glutamate uptake correlates negatively with an increase in the incidence of orofacial diskinesia.", "completion": "{\"entities\": [{\"text\": \"glutamate\", \"type\": \"Chemical\"}, {\"text\": \"orofacial diskinesia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04080", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Acute effects of N-(2-propylpentanoyl)urea on hippocampal amino acid neurotransmitters in pilocarpine - induced seizure in rats.", "completion": "{\"entities\": [{\"text\": \"N-(2-propylpentanoyl)urea\", \"type\": \"Chemical\"}, {\"text\": \"amino acid\", \"type\": \"Chemical\"}, {\"text\": \"pilocarpine\", \"type\": \"Chemical\"}, {\"text\": \"seizure\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04149", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In multivariate analysis, a significant correlation between DBP reduction and worsening of the neurological score was found for the high - dose group (beta = 0.", "completion": "{\"entities\": [{\"text\": \"DBP reduction\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01320", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Study participants were randomized to receive 10 mg of prochlorperazine administered intravenously by means of 2 - minute push (bolus group) or 10 mg diluted in 50 mL of normal saline solution administered by means of intravenous infusion during a 15 - minute period (infusion group ). The main outcome was the number of study participants experiencing akathisia within 60 minutes of administration.", "completion": "{\"entities\": [{\"text\": \"prochlorperazine\", \"type\": \"Chemical\"}, {\"text\": \"akathisia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02728", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These short - term studies showed that enalapril reduced arterial blood pressure (101 +/- 2 vs.", "completion": "{\"entities\": [{\"text\": \"enalapril\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01935", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The occurrence of infarcts were confirmed by histological methods.", "completion": "{\"entities\": [{\"text\": \"infarcts\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04991", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The effectiveness of administration of glycopyrrolate 5 and 10 micrograms kg - 1 and atropine 10 and 20 micrograms kg - 1 i.", "completion": "{\"entities\": [{\"text\": \"glycopyrrolate\", \"type\": \"Chemical\"}, {\"text\": \"atropine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03290", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A new infarct - avid radiopharmaceutical based on glucaric acid was prepared in the hospital radiopharmacy of the INCMNSZ.", "completion": "{\"entities\": [{\"text\": \"infarct\", \"type\": \"Disease\"}, {\"text\": \"glucaric acid\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04624", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: INTRODUCTION: Intoxications with carbachol, a muscarinic cholinergic receptor agonist are rare.", "completion": "{\"entities\": [{\"text\": \"carbachol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01429", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 mg / kg BW) immediately or 30 min after the single SC injection of DFP.", "completion": "{\"entities\": [{\"text\": \"DFP\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00572", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Conversely, down - regulation of alphaENaC, betaENaC and gammaENaC mRNA expression on day 3 occurred in the presence of high aldosterone concentrations, and was followed by a return of sodium excretion to control values.", "completion": "{\"entities\": [{\"text\": \"aldosterone\", \"type\": \"Chemical\"}, {\"text\": \"sodium\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01079", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This complication reappeared on day 25 during the second dose of 5-fluorouracil and folinic acid, which were then the only drugs given.", "completion": "{\"entities\": [{\"text\": \"5-fluorouracil\", \"type\": \"Chemical\"}, {\"text\": \"folinic acid\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02620", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 2) and haloperidol (- 15.", "completion": "{\"entities\": [{\"text\": \"haloperidol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03078", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Twenty children with acute lymphoblastic leukemia who developed meningeal disease were treated with a high - dose intravenous methotrexate regimen that was designed to achieve and maintain CSF methotrexate concentrations of 10 (- 5) mol / L without the need for concomitant intrathecal dosing.", "completion": "{\"entities\": [{\"text\": \"acute lymphoblastic leukemia\", \"type\": \"Disease\"}, {\"text\": \"meningeal disease\", \"type\": \"Disease\"}, {\"text\": \"methotrexate\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04996", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Bradycardia (defined as a decrease in heart rate to less than 50 beat min - 1) was prevented when the larger dose of either active drug was used.", "completion": "{\"entities\": [{\"text\": \"Bradycardia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04476", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: In the population based, nationwide Swedish Inpatient Register a cohort of 1065 patients with Wegener's granulomatosis, 1969 - 95, was identified.", "completion": "{\"entities\": [{\"text\": \"Wegener's granulomatosis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00593", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The patient was asymptomatic and the aneurysm was detected in a routine control.", "completion": "{\"entities\": [{\"text\": \"aneurysm\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00767", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Neonatal cardiomyocytes were isolated from Sprague - Dawley rat hearts and randomly divided into controls, an adriamycin - treated group, and a 3MA plus adriamycin - treated group.", "completion": "{\"entities\": [{\"text\": \"adriamycin\", \"type\": \"Chemical\"}, {\"text\": \"3MA\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03096", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: m .), enhanced the later (60 - 120 min) nicotine - induced hyperactivity, and raised spontaneous nocturnal activity.", "completion": "{\"entities\": [{\"text\": \"nicotine\", \"type\": \"Chemical\"}, {\"text\": \"hyperactivity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04151", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 048 ). Patients with a DBP reduction of > or = 20% in the high - dose group had a significantly increased adjusted OR for the compound outcome variable death or dependency (Barthel Index < 60 )(n / N = 25 / 26, OR 10.", "completion": "{\"entities\": [{\"text\": \"DBP reduction\", \"type\": \"Disease\"}, {\"text\": \"death\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03392", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Valproic acid (VPA) is a broad - spectrum antiepileptic drug and is usually well - tolerated.", "completion": "{\"entities\": [{\"text\": \"Valproic acid\", \"type\": \"Chemical\"}, {\"text\": \"VPA\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00037", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: NX + HP caused a further rise in blood pressure in Li - pretreated rats.", "completion": "{\"entities\": [{\"text\": \"Li\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04995", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A frequency of bradycardia of 50% was noted in the control group, but this was not significantly different from the frequency with the active drugs.", "completion": "{\"entities\": [{\"text\": \"bradycardia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00422", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Acute hepatitis, autoimmune hemolytic anemia, and erythroblastocytopenia induced by ceftriaxone.", "completion": "{\"entities\": [{\"text\": \"hepatitis\", \"type\": \"Disease\"}, {\"text\": \"autoimmune hemolytic anemia\", \"type\": \"Disease\"}, {\"text\": \"erythroblastocytopenia\", \"type\": \"Disease\"}, {\"text\": \"ceftriaxone\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-reassigned-03680", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Withdrawals occurred in 27.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02443", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The HBV viral loads for mono - infected and co - infected patients ranged from 3.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00145", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Based on this principle a 27 - year old woman, classified as being in the high - risk group (Goldstein and Berkowitz score: 11 ), was treated with multiple cytotoxic drugs.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01501", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The results support the important potential of GNC92H2 as a therapeutic tool against cocaine overdose", "completion": "{\"entities\": [{\"text\": \"GNC92H2\", \"type\": \"Chemical\"}, {\"text\": \"cocaine overdose\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03750", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Although the intraocular pressure elevation caused by secondary acute angle - closure glaucoma decreased and ocular pain diminished, inexorable papilledema and exudative retinal detachment continued for 3 weeks.", "completion": "{\"entities\": [{\"text\": \"glaucoma\", \"type\": \"Disease\"}, {\"text\": \"ocular pain\", \"type\": \"Disease\"}, {\"text\": \"papilledema\", \"type\": \"Disease\"}, {\"text\": \"retinal detachment\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02970", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Postural tremor was measured with the arm horizontally outstretched rest tremor with the arm supported by an armrest and finally tremor was measured after holding a 2 - kg weight until exhaustion.", "completion": "{\"entities\": [{\"text\": \"tremor\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00960", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We describe eight patients in whom cocaine use was related to stroke and review 39 cases from the literature.", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"stroke\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04827", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The open study lasted for four weeks; the drug was administrated in the form of 1 mg tablets.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02041", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Reduced size of capillary lumen and occlusion were caused by swollen endothelial cells which had luminal protrusions and swollen microvilli.", "completion": "{\"entities\": [{\"text\": \"luminal\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04949", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Prolactin exceeded 20 ng ./ ml.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01985", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 6 h after the administration of amiloride, a reduction was observed in the lithium content of the renal medulla but not in the other organs studied.", "completion": "{\"entities\": [{\"text\": \"amiloride\", \"type\": \"Chemical\"}, {\"text\": \"lithium\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04508", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In each patient who had abnormalities on the initial MR study, a follow - up MR study was performed 1 month later.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-reassigned-02567", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 7 micrograms after atenolol.", "completion": "{\"entities\": [{\"text\": \"atenolol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00402", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05 )). These results suggest that PGE1 may be preferable to TMP for hypotensive anaesthesia in spinal surgery because TMP", "completion": "{\"entities\": [{\"text\": \"PGE1\", \"type\": \"Chemical\"}, {\"text\": \"TMP\", \"type\": \"Chemical\"}, {\"text\": \"hypotensive\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00102", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In both cases normal plasma and urinary free cortisol levels had been achieved following ketoconazole therapy, yet continuous blood pressure monitoring demonstrated hypertension 31 (patient 1) and 52 weeks (patient 2) after treatment.", "completion": "{\"entities\": [{\"text\": \"cortisol\", \"type\": \"Chemical\"}, {\"text\": \"ketoconazole\", \"type\": \"Chemical\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02181", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Treatments have included discontinuation or reduction of cyclosporine dose with or without concurrent plasma exchange, plasma infusion, anticoagulation, and intravenous immunoglobulin G infusion.", "completion": "{\"entities\": [{\"text\": \"cyclosporine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04774", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Adverse reactions possibly attributable to didanosine were common.", "completion": "{\"entities\": [{\"text\": \"didanosine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04224", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Neurologic effects of subarachnoid administration of 2-chloroprocaine-CE, bupivacaine, and low pH normal saline in dogs.", "completion": "{\"entities\": [{\"text\": \"2-chloroprocaine-CE\", \"type\": \"Chemical\"}, {\"text\": \"bupivacaine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01236", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A respiratory arrest with severe desaturation and bradycardia occurred.", "completion": "{\"entities\": [{\"text\": \"respiratory arrest\", \"type\": \"Disease\"}, {\"text\": \"desaturation\", \"type\": \"Disease\"}, {\"text\": \"bradycardia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04022", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Motor behavior, passive avoidance, and skilled forelimb function were tested repeatedly for six weeks.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-reassigned-03508", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: p .) or haloperidol (1 mg / kg i.", "completion": "{\"entities\": [{\"text\": \"haloperidol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05147", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Dimensions of the bruising on the heparin applied areas were measured using transparent millimetric measuring paper.", "completion": "{\"entities\": [{\"text\": \"bruising\", \"type\": \"Disease\"}, {\"text\": \"heparin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01000", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Anaesthesia was maintained with an inspired isoflurane concentration of 0.", "completion": "{\"entities\": [{\"text\": \"isoflurane\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05041", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Treatment of tinnitus by intratympanic instillation of lignocaine (lidocaine) 2 per cent through ventilation tubes.", "completion": "{\"entities\": [{\"text\": \"tinnitus\", \"type\": \"Disease\"}, {\"text\": \"lignocaine\", \"type\": \"Chemical\"}, {\"text\": \"lidocaine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-05142", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: Although different methods to prevent bruising and pain following the subcutaneous injection of heparin have been widely studied and described, the effect of injection duration on the occurrence of bruising and pain is little documented.", "completion": "{\"entities\": [{\"text\": \"bruising\", \"type\": \"Disease\"}, {\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"heparin\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03182", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: While the elevations of the upper lid margin in most subjects were not more than 2 mm and did not cause noticeable change in appearance, one subject suffered from mechanical entropion and marked corneal abrasion", "completion": "{\"entities\": [{\"text\": \"entropion\", \"type\": \"Disease\"}, {\"text\": \"corneal abrasion\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02770", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Ketamine hydrochloride was administered intravenously (at a dose of two milligrams per kilogram of body weight) in ninety - nine of the patients and intramuscularly (at a dose of four milligrams per kilogram of body weight) in the other fifteen.", "completion": "{\"entities\": [{\"text\": \"Ketamine hydrochloride\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00439", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: p .), a positive control, showed only 30% inhibition.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03159", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 1 %), including 4 complete responses (11.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04785", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In contrast with the literature, serum levels of angiogenesis factors did not change significantly by pegylated interferon and ribavirin therapy.", "completion": "{\"entities\": [{\"text\": \"pegylated interferon\", \"type\": \"Chemical\"}, {\"text\": \"ribavirin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03850", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: All four recovered completely without neurological sequelae following the withdrawal of the offending agents.", "completion": "{\"entities\": [{\"text\": \"neurological sequelae\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02560", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This report demonstrates that not only intravenous, but also oral bisphosphonates can aggravate proteinuria and acute renal failure", "completion": "{\"entities\": [{\"text\": \"bisphosphonates\", \"type\": \"Chemical\"}, {\"text\": \"proteinuria\", \"type\": \"Disease\"}, {\"text\": \"acute renal failure\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04943", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Main clinical criteria tested regarding efficiency in hormone determination were low sexual desire, small testes and gynecomastia.", "completion": "{\"entities\": [{\"text\": \"low sexual desire\", \"type\": \"Disease\"}, {\"text\": \"gynecomastia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04520", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The authors report 2 cases of premature neonates who had enterocutaneous fistula complicating necrotizing enterocolitis.", "completion": "{\"entities\": [{\"text\": \"fistula\", \"type\": \"Disease\"}, {\"text\": \"necrotizing enterocolitis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01365", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05 ). Male rats that received prenatal dexamethasone on days 15 and 16, 17 and 18, and 13 and 14 of gestation had elevated blood pressures at 6 months of age; the latter group did not have a reduction in glomerular number.", "completion": "{\"entities\": [{\"text\": \"dexamethasone\", \"type\": \"Chemical\"}, {\"text\": \"elevated blood pressures\", \"type\": \"Disease\"}, {\"text\": \"reduction in glomerular number\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02319", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Similar mechanisms may be involved in the pathogenesis of cluster headache", "completion": "{\"entities\": [{\"text\": \"cluster headache\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03688", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The drug was withdrawn on presentation to hospital in 11 patients, with rapid clinical improvement in 9.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03354", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A single MPEP (5 mg / kg ip) injection reduced the basal extracellular dopamine level in the striatum, as well as dopamine release stimulated either by methamphetamine (10 mg / kg sc) or by intrastriatally administered veratridine (100 microM ). Moreover, it transiently diminished the methamphetamine (10 mg / kg sc )- induced hyperthermia and reduced basal body temperature.", "completion": "{\"entities\": [{\"text\": \"MPEP\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}, {\"text\": \"methamphetamine\", \"type\": \"Chemical\"}, {\"text\": \"veratridine\", \"type\": \"Chemical\"}, {\"text\": \"hyperthermia\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-02799", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We analyzed the following events: complications related with the topical anesthesia, with MZ use and with the procedure.", "completion": "{\"entities\": [{\"text\": \"MZ\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01295", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Torsades de pointes (TDP) is a potentially fatal ventricular tachycardia associated with increases in QT interval and monophasic action potential duration (MAPD ). TDP is a side - effect that has led to withdrawal of several drugs from the market (e.", "completion": "{\"entities\": [{\"text\": \"Torsades de pointes\", \"type\": \"Disease\"}, {\"text\": \"TDP\", \"type\": \"Disease\"}, {\"text\": \"ventricular tachycardia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-reassigned-04597", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After a period of 2.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03615", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The effect of high dose D-penicillamine treatment on aortic permeability to albumin and on the ultrastructure of the vessel.", "completion": "{\"entities\": [{\"text\": \"D-penicillamine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00360", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Effect of coniine on the developing chick embryo.", "completion": "{\"entities\": [{\"text\": \"coniine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02422", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: To develop a novel and effective drug that could enhance cognitive function and neuroprotection, we newly synthesized maltolyl p-coumarate by the esterification of maltol and p-coumaric acid.", "completion": "{\"entities\": [{\"text\": \"maltol\", \"type\": \"Chemical\"}, {\"text\": \"maltolyl p-coumarate\", \"type\": \"Chemical\"}, {\"text\": \"p-coumaric acid\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04383", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: PD female rats also showed increased (3) H - haloperidol binding and decreased dopamine transporter binding in striatum.", "completion": "{\"entities\": [{\"text\": \"H\", \"type\": \"Chemical\"}, {\"text\": \"haloperidol\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01554", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: All of the symptoms were completely resolved over the next 8 hours.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01742", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Therefore, in adult patients affected by HUS, dialysis should not be discontinued prematurely; moreover, bilateral nephrectomy, for treatment of severe hypertension and microangiopathic hemolytic anemia", "completion": "{\"entities\": [{\"text\": \"HUS\", \"type\": \"Disease\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}, {\"text\": \"microangiopathic hemolytic anemia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04074", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Isoproterenol - treated rats showed significant increases in the levels of lactate dehydrogenase, aspartate transaminase, creatine kinase and malondialdehyde and significant decreases in the activities of superoxide dismutase, catalase and glutathione peroxidase in serum and heart.", "completion": "{\"entities\": [{\"text\": \"Isoproterenol\", \"type\": \"Chemical\"}, {\"text\": \"lactate\", \"type\": \"Chemical\"}, {\"text\": \"aspartate\", \"type\": \"Chemical\"}, {\"text\": \"creatine\", \"type\": \"Chemical\"}, {\"text\": \"malondialdehyde\", \"type\": \"Chemical\"}, {\"text\": \"superoxide\", \"type\": \"Chemical\"}, {\"text\": \"glutathione\", \"type\": \"Chemical\"}]}", "n_entities": 7}
{"ref": "bc5cdr-train-00173", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: One week prior to admission a therapy with standard doses of metoprolol (100 mg t.", "completion": "{\"entities\": [{\"text\": \"metoprolol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00039", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In this model of chronic renal failure", "completion": "{\"entities\": [{\"text\": \"chronic renal failure\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00508", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 mM ). Pathologically, granular cytoplasmic changes were found in cardiac myocytes, indicating enlarged, damaged mitochondria.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03102", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: OBJECTIVES: To assess the added diagnostic value of a new cardiac performance index (dP / dtejc) measurement, based on brachial artery flow changes, as compared to standard 12 - lead ECG, for detecting dobutamine - induced myocardial ischemia, using Tc99m-Sestamibi single - photon emission computed tomography as the gold standard of comparison to assess the presence or absence of ischemia.", "completion": "{\"entities\": [{\"text\": \"dobutamine\", \"type\": \"Chemical\"}, {\"text\": \"myocardial ischemia\", \"type\": \"Disease\"}, {\"text\": \"ischemia\", \"type\": \"Disease\"}, {\"text\": \"Tc99m-Sestamibi\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03330", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05 ), interstitial collagen III (r = 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04470", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Severe reversible left ventricular systolic and diastolic dysfunction due to accidental iatrogenic epinephrine overdose.", "completion": "{\"entities\": [{\"text\": \"left ventricular systolic and diastolic dysfunction\", \"type\": \"Disease\"}, {\"text\": \"epinephrine\", \"type\": \"Chemical\"}, {\"text\": \"overdose\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00596", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Urotensin-II (U-II) receptors are widely distributed in the central nervous system.", "completion": "{\"entities\": [{\"text\": \"Urotensin-II\", \"type\": \"Chemical\"}, {\"text\": \"U-II\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02099", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The importance of this association was evaluated in Belgium while this country still had no restriction on the prescription of appetite suppressants.", "completion": "{\"entities\": [{\"text\": \"appetite suppressants\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01894", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Serial studies of auditory neurotoxicity in patients receiving deferoxamine therapy.", "completion": "{\"entities\": [{\"text\": \"auditory neurotoxicity\", \"type\": \"Disease\"}, {\"text\": \"deferoxamine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03457", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 mg enalapril or 0.", "completion": "{\"entities\": [{\"text\": \"enalapril\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04548", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A range of strain specific sensitivities was documented with A / J and SJL mice being most sensitive and C57BL / 6J most resistant.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03826", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Clinical tolerability of both agents has been good, with fewer than 3% of patients withdrawn from treatment because of clinical adverse experiences.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01950", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the nine responders, median duration of chemotherapy response from the time of operation was 25 weeks (range 12 to more than 91 weeks ). The median duration of survival in the 12 patients was 54 weeks (range 21 to more than 156 weeks ), with an 18 - month survival rate of 42 %. Twenty - four patients with recurrent Grade I to IV astrocytomas, whose resection and irradiation therapy had failed, received two to eight courses of intra - arterial BCNU therapy.", "completion": "{\"entities\": [{\"text\": \"astrocytomas\", \"type\": \"Disease\"}, {\"text\": \"BCNU\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01190", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The male Wistar rats consuming a diet that contained LiCl (60 mmol / kg) for 4 weeks developed marked polyuria.", "completion": "{\"entities\": [{\"text\": \"LiCl\", \"type\": \"Chemical\"}, {\"text\": \"polyuria\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03481", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Independent but not additive effects of Na and Ca are shown by decreases in the values of [verapamil] o needed to reduce BF by 30 %(IC30) with the following order of inhibitory potency: LNa > LCa > HCa > N, resulting LNa + HCa similar to LNa.", "completion": "{\"entities\": [{\"text\": \"Na\", \"type\": \"Chemical\"}, {\"text\": \"Ca\", \"type\": \"Chemical\"}, {\"text\": \"verapamil\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00624", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In recent years working memory deficits have been reported in users of MDMA (3,4-methylenedioxymethamphetamine, ecstasy ). The current study aimed to assess the impact of MDMA use on three separate central executive processes (set shifting, inhibition and memory updating) and also on\" prefrontal\" mediated social and emotional judgement processes.", "completion": "{\"entities\": [{\"text\": \"memory deficits\", \"type\": \"Disease\"}, {\"text\": \"MDMA\", \"type\": \"Chemical\"}, {\"text\": \"3,4-methylenedioxymethamphetamine\", \"type\": \"Chemical\"}, {\"text\": \"ecstasy\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00282", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After 2 weeks of treatment, patients tested 5 - 8 h after the last dose of medication did not show any decrement of performance.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04431", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A comparable overexpression of Pgp in the BBB was obtained after pilocarpine - induced seizures in wild - type Wistar rats.", "completion": "{\"entities\": [{\"text\": \"pilocarpine\", \"type\": \"Chemical\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04440", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We report QTLs identified using a B6 (host) x A / J (donor) CSS panel to localize genes involved in susceptibility to pilocarpine - induced seizures.", "completion": "{\"entities\": [{\"text\": \"pilocarpine\", \"type\": \"Chemical\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03472", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Basal frequency (BF) evaluated by surface electrogram was 223 +/- 4 beats / min.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04510", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Of the 14 patients, 5 (35.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03282", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05 ). Endothelial - dependent relaxation and eNOS mRNA expression were greater in the Dex + Ato group than in the Dex only group (P < 0.", "completion": "{\"entities\": [{\"text\": \"Dex\", \"type\": \"Chemical\"}, {\"text\": \"Ato\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04847", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Curcumin co - administration did not cause any significant alteration in the serum concentrations of both phenobarbitone as well as carbamazepine.", "completion": "{\"entities\": [{\"text\": \"Curcumin\", \"type\": \"Chemical\"}, {\"text\": \"phenobarbitone\", \"type\": \"Chemical\"}, {\"text\": \"carbamazepine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04622", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These experiments suggest that although many factors may contribute to the increased incidence of ventricular arrhythmias in respiratory failure, pharmacologic agents, particularly aminophylline", "completion": "{\"entities\": [{\"text\": \"ventricular arrhythmias\", \"type\": \"Disease\"}, {\"text\": \"respiratory failure\", \"type\": \"Disease\"}, {\"text\": \"aminophylline\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02530", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A restrictive pattern of valvular regurgitation, suggestive of the role of pergolide, was observed in 12 / 30 (40 %) patients including two with heart failure.", "completion": "{\"entities\": [{\"text\": \"valvular regurgitation\", \"type\": \"Disease\"}, {\"text\": \"pergolide\", \"type\": \"Chemical\"}, {\"text\": \"heart failure\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03220", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The present study was designed to investigate the hypothesis that calcium channel blockers in general induce cardiovascular malformations indicating a pharmacologic class effect.", "completion": "{\"entities\": [{\"text\": \"calcium\", \"type\": \"Chemical\"}, {\"text\": \"cardiovascular malformations\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01978", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 2 g / dl, splenomegaly 2 - 3 times normal, and testicular atrophy approximately half normal weight) after 12 doses of carbon tetrachloride given intragastrically in the phenobarbitone - primed rat was increased from 25% to 56% by giving the initial\" calibrating\" dose of carbon tetrachloride at the peak of the phenobarbitone - induced enlargement of the liver.", "completion": "{\"entities\": [{\"text\": \"splenomegaly\", \"type\": \"Disease\"}, {\"text\": \"atrophy\", \"type\": \"Disease\"}, {\"text\": \"carbon tetrachloride\", \"type\": \"Chemical\"}, {\"text\": \"phenobarbitone\", \"type\": \"Chemical\"}, {\"text\": \"enlargement of the liver\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-05210", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: There seemed to be no direct correlation between the dose or duration used and the severity of bone marrow suppression.", "completion": "{\"entities\": [{\"text\": \"bone marrow suppression\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00331", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Renal biopsy revealed severe glomerulonephritis with crescents, electron dense fibrillar deposits and moderate lymphocytic interstitial infiltrate.", "completion": "{\"entities\": [{\"text\": \"glomerulonephritis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03749", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: He was treated with intravenous administration of corticosteroids and glycerin for 6 days after the injection.", "completion": "{\"entities\": [{\"text\": \"glycerin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03300", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: OBJECTIVE: The goal of this study was to compare the efficacy and side effects of two doses of haloperidol and placebo in the treatment of psychosis and disruptive behaviors in patients with Alzheimer's disease.", "completion": "{\"entities\": [{\"text\": \"haloperidol\", \"type\": \"Chemical\"}, {\"text\": \"psychosis\", \"type\": \"Disease\"}, {\"text\": \"disruptive behaviors\", \"type\": \"Disease\"}, {\"text\": \"Alzheimer's disease\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02146", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After recovery of blood pressure to control values, the extrusion of Na + from cardiac cells was normalized, as revealed by restoration of the (Na, K", "completion": "{\"entities\": [{\"text\": \"Na\", \"type\": \"Chemical\"}, {\"text\": \"K\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02287", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 1 years, hospitalized for 24.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03222", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pregnant rats were administered one of these calcium channel blockers during the period of cardiac morphogenesis and the offspring examined on day 20 of gestation for cardiovascular malformations.", "completion": "{\"entities\": [{\"text\": \"calcium\", \"type\": \"Chemical\"}, {\"text\": \"cardiovascular malformations\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01038", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Attention to the possible induction of specific tardive dyskinesia", "completion": "{\"entities\": [{\"text\": \"tardive dyskinesia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01536", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: There was a remarkable reduction in total cholesterol level as well, to the extent of 23% in young and 21% in aged animals with this dose of DCE.", "completion": "{\"entities\": [{\"text\": \"cholesterol\", \"type\": \"Chemical\"}, {\"text\": \"DCE\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02138", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In several models of hypertension, elevation of intracellular sodium level was documented in cardiac tissue.", "completion": "{\"entities\": [{\"text\": \"hypertension\", \"type\": \"Disease\"}, {\"text\": \"sodium\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01889", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It is concluded that patients on 5-FU treatment should be under close supervision and that the treatment should be discontinued if chest pain or tachyarrhythmia", "completion": "{\"entities\": [{\"text\": \"5-FU\", \"type\": \"Chemical\"}, {\"text\": \"chest pain\", \"type\": \"Disease\"}, {\"text\": \"tachyarrhythmia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-reassigned-00652", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: All-trans retinoic acid - induced inflammatory myositis in a patient with acute promyelocytic leukemia.", "completion": "{\"entities\": [{\"text\": \"All-trans retinoic acid\", \"type\": \"Chemical\"}, {\"text\": \"myositis\", \"type\": \"Disease\"}, {\"text\": \"acute promyelocytic leukemia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03745", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, we experienced a case of severe ocular and orbital toxicity after intracarotid injection of carboplatin, which is infrequently reported.", "completion": "{\"entities\": [{\"text\": \"ocular and orbital toxicity\", \"type\": \"Disease\"}, {\"text\": \"carboplatin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04618", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: During the infusion of aminophylline, the ventricular fibrillation threshold was reduced by 30 to 40 percent of the control when pH and partial pressures of oxygen (PO2) and carbon dioxide (CO2) were kept within normal limits.", "completion": "{\"entities\": [{\"text\": \"aminophylline\", \"type\": \"Chemical\"}, {\"text\": \"ventricular fibrillation\", \"type\": \"Disease\"}, {\"text\": \"oxygen\", \"type\": \"Chemical\"}, {\"text\": \"PO2\", \"type\": \"Chemical\"}, {\"text\": \"carbon dioxide\", \"type\": \"Chemical\"}, {\"text\": \"CO2\", \"type\": \"Chemical\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-00543", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Systemic cocaine (10 mg / kg) significantly increased the locomotor activity of rats.", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00443", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Gemcitabine plus vinorelbine in nonsmall cell lung carcinoma patients age 70 years or older or patients who cannot receive cisplatin.", "completion": "{\"entities\": [{\"text\": \"Gemcitabine\", \"type\": \"Chemical\"}, {\"text\": \"vinorelbine\", \"type\": \"Chemical\"}, {\"text\": \"nonsmall cell lung carcinoma\", \"type\": \"Disease\"}, {\"text\": \"cisplatin\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00096", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We report the case of a patient who developed acute hepatitis with extensive hepatocellular necrosis, 7 months after the onset of administration of clotiazepam, a thienodiazepine derivative.", "completion": "{\"entities\": [{\"text\": \"hepatitis\", \"type\": \"Disease\"}, {\"text\": \"extensive hepatocellular necrosis\", \"type\": \"Disease\"}, {\"text\": \"clotiazepam\", \"type\": \"Chemical\"}, {\"text\": \"thienodiazepine\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03538", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: By using transthoracic echocardiography, anterior and posterior wall thickness, LV diameters and LV fractional shortening (FS) were measured in all rats before DOX or saline, and at weeks 6 and 9 after treatment in all surviving rats.", "completion": "{\"entities\": [{\"text\": \"DOX\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03757", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The histology comprised squamous carcinoma (11 ), adenocarcinoma (1 ), mixed histology (2 ), bronchio-alveolar carcinoma (1) and large cell undifferentiated carcinoma (1 ). Neutropenia grade greater than or equal to 3 was seen in 15 patients, infections with recovery in 3, and grand mal seizures in 1 patient.", "completion": "{\"entities\": [{\"text\": \"squamous carcinoma\", \"type\": \"Disease\"}, {\"text\": \"adenocarcinoma\", \"type\": \"Disease\"}, {\"text\": \"bronchio-alveolar carcinoma\", \"type\": \"Disease\"}, {\"text\": \"undifferentiated carcinoma\", \"type\": \"Disease\"}, {\"text\": \"Neutropenia\", \"type\": \"Disease\"}, {\"text\": \"infections\", \"type\": \"Disease\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}]}", "n_entities": 7}
{"ref": "bc5cdr-train-01848", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Administration of ribavirin resulted in a neutralization of viremia and a drop of endogenous interferon titers.", "completion": "{\"entities\": [{\"text\": \"ribavirin\", \"type\": \"Chemical\"}, {\"text\": \"viremia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00322", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the adriamycin - treated cells, the addition of adenosine", "completion": "{\"entities\": [{\"text\": \"adriamycin\", \"type\": \"Chemical\"}, {\"text\": \"adenosine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03206", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the present experiment calcitonin decreased locomotor activity when locally injected into the same sites where it decreases food intake.", "completion": "{\"entities\": [{\"text\": \"calcitonin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00315", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Metabolic involvement in adriamycin cardiotoxicity.", "completion": "{\"entities\": [{\"text\": \"adriamycin\", \"type\": \"Chemical\"}, {\"text\": \"cardiotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00778", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We performed this study in order to describe the main characteristics of this adverse drug reaction.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00729", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Multivariate analysis showed a 2.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03890", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Administration of THP (3.", "completion": "{\"entities\": [{\"text\": \"THP\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05042", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Idiopathic subjective tinnitus (IST) is one of the most obscure otological pathologies.", "completion": "{\"entities\": [{\"text\": \"Idiopathic subjective tinnitus\", \"type\": \"Disease\"}, {\"text\": \"IST\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04316", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The data strengthen the evidence that the neurotoxic effect of amphetamine and related compounds toward nigrostriatal dopamine neurons involves NMDA receptors and that LY274614 is an NMDA", "completion": "{\"entities\": [{\"text\": \"neurotoxic\", \"type\": \"Disease\"}, {\"text\": \"amphetamine\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}, {\"text\": \"NMDA\", \"type\": \"Chemical\"}, {\"text\": \"LY274614\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-00472", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This observation suggests that increased susceptibility to Warfarin - induced artery calcification could be related to higher serum phosphate levels.", "completion": "{\"entities\": [{\"text\": \"Warfarin\", \"type\": \"Chemical\"}, {\"text\": \"artery calcification\", \"type\": \"Disease\"}, {\"text\": \"phosphate\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-reassigned-03799", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 7 cells per field; p < 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-05111", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These results provide empirical support for conducting a further study of bupropion", "completion": "{\"entities\": [{\"text\": \"bupropion\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00356", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Current medications did not include angiotensin - converting enzyme inhibitors or beta - blockers.", "completion": "{\"entities\": [{\"text\": \"angiotensin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00964", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Stroke followed cocaine use by inhalation, intranasal, intravenous, and intramuscular routes.", "completion": "{\"entities\": [{\"text\": \"Stroke\", \"type\": \"Disease\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03873", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Three yr after transplantation she developed renal Fanconi syndrome with severe metabolic acidosis, hypophosphatemia, glycosuria, and aminoaciduria.", "completion": "{\"entities\": [{\"text\": \"renal Fanconi syndrome\", \"type\": \"Disease\"}, {\"text\": \"metabolic acidosis\", \"type\": \"Disease\"}, {\"text\": \"hypophosphatemia\", \"type\": \"Disease\"}, {\"text\": \"glycosuria\", \"type\": \"Disease\"}, {\"text\": \"aminoaciduria\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-00866", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Ten cm H2O CPAP before nitroprusside infusion produced a further decrease in arterial blood pressure and significantly increased heart rate and decreased cardiac output and QS / QT.", "completion": "{\"entities\": [{\"text\": \"H2O\", \"type\": \"Chemical\"}, {\"text\": \"nitroprusside\", \"type\": \"Chemical\"}, {\"text\": \"decrease in arterial blood pressure\", \"type\": \"Disease\"}, {\"text\": \"decreased cardiac output\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00075", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 mEq / L, which is usually well tolerated.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03369", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Fewer subjects reported adverse events following treatment with desipramine alone than when receiving desipramine with cinacalcet (33 versus 86 %), the most frequent of which (nausea and headache) have been reported for patients treated with either desipramine or cinacalcet.", "completion": "{\"entities\": [{\"text\": \"desipramine\", \"type\": \"Chemical\"}, {\"text\": \"cinacalcet\", \"type\": \"Chemical\"}, {\"text\": \"nausea\", \"type\": \"Disease\"}, {\"text\": \"headache\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04457", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: OBJECTIVES: Thrombotic microangiopathy is a well - known problem in patients following renal transplantation.", "completion": "{\"entities\": [{\"text\": \"Thrombotic microangiopathy\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02437", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thirty - five lamivudine - na ve HBV infected patients with or without HIV co-infection were studied: 15 chronic HBV mono-infected patients and 20 HBV-HIV co-infected patients.", "completion": "{\"entities\": [{\"text\": \"lamivudine\", \"type\": \"Chemical\"}, {\"text\": \"na\", \"type\": \"Chemical\"}, {\"text\": \"HBV infected\", \"type\": \"Disease\"}, {\"text\": \"HIV co-infection\", \"type\": \"Disease\"}, {\"text\": \"HBV mono-infected\", \"type\": \"Disease\"}, {\"text\": \"HBV-HIV co-infected\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-02687", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Abstract Serum aminotransferase elevations are a commonly known adverse effect of 3 - hydroxy - 3 - methylglutaryl coenzyme A reductase inhibitor (statin) therapy.", "completion": "{\"entities\": [{\"text\": \"statin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02556", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Within 14 days of the oral bisphosphonate (alendronate sodium) administration, the amount of daily urinary protein increased rapidly up to 12.", "completion": "{\"entities\": [{\"text\": \"bisphosphonate\", \"type\": \"Chemical\"}, {\"text\": \"alendronate sodium\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04343", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: TIMP mRNA and tissue levels did not differ obviously among the three aortic segments.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01693", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A brain imaging study and repetitive nerve stimulation test indicated no abnormality.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01355", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: These results suggest that differences in cholinergic activity and postsynaptic sensitivity to cholinergic convulsants may be associated with ethanol withdrawal severity and implicate cholinergic mechanisms in alcohol withdrawal.", "completion": "{\"entities\": [{\"text\": \"convulsants\", \"type\": \"Disease\"}, {\"text\": \"ethanol\", \"type\": \"Chemical\"}, {\"text\": \"alcohol\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04724", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: A comparison of frequency of adverse reactions to indocyanine green with the previously reported frequency of such reactions to fluorescein sodium indicated that indocyanine green is a safe as fluorescein", "completion": "{\"entities\": [{\"text\": \"indocyanine green\", \"type\": \"Chemical\"}, {\"text\": \"fluorescein\", \"type\": \"Chemical\"}, {\"text\": \"fluorescein sodium\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00653", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In 40% it increased by more than 100 %. Twenty - eight percent of patients showed increased proteinuria to the nephrotic range.", "completion": "{\"entities\": [{\"text\": \"proteinuria\", \"type\": \"Disease\"}, {\"text\": \"nephrotic\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00864", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Before nitroprusside infusion, 5 cm H2O CPAP significantly, P less than.", "completion": "{\"entities\": [{\"text\": \"nitroprusside\", \"type\": \"Chemical\"}, {\"text\": \"H2O\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04780", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We aimed to investigate whether there is a relation between hemoglobin, haptoglobin and angiogenesis soluble markers which are modifiable and can help in developing strategies against anemia.", "completion": "{\"entities\": [{\"text\": \"anemia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05025", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Renal tissue was obtained for determination of glomerular size and sclerosis.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00770", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In addition, we analyzed the expression of autophagy associated gene, beclin 1 using RT - PCR and Western blotting in an animal model.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00532", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0) for those without a prothrombotic mutation and 1.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01796", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In a risk analysis of neuropsychiatric side effects in Germany, it is estimated that one of 8, 000 mefloquine users suffers from such reactions.", "completion": "{\"entities\": [{\"text\": \"mefloquine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03635", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: On the other hand, BNP did not increase in the patients without heart failure given DNR, even at more than 700 mg / m (2 ). The plasma level of ANP did not always increase in all the patients with clinical and subclinical heart failure.", "completion": "{\"entities\": [{\"text\": \"heart failure\", \"type\": \"Disease\"}, {\"text\": \"DNR\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01817", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Mazindol did not benefit strength at any point in the study.", "completion": "{\"entities\": [{\"text\": \"Mazindol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02714", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In particular it illustrates the derangements of thyroid function seen in pregnant women with eating disorders and reminds us that when a cause for thyrotoxicosis remains obscure, thyroxine", "completion": "{\"entities\": [{\"text\": \"eating disorders\", \"type\": \"Disease\"}, {\"text\": \"thyrotoxicosis\", \"type\": \"Disease\"}, {\"text\": \"thyroxine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02982", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Increased frequency of venous thromboembolism with the combination of docetaxel and thalidomide in patients with metastatic androgen - independent prostate cancer.", "completion": "{\"entities\": [{\"text\": \"venous thromboembolism\", \"type\": \"Disease\"}, {\"text\": \"docetaxel\", \"type\": \"Chemical\"}, {\"text\": \"thalidomide\", \"type\": \"Chemical\"}, {\"text\": \"prostate cancer\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04821", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Further studies on the effects of certain irrigating fluids on the rat bladder for 18 hours are reported.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04001", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: Sirolimus (SRL) may supplement calcineurin inhibitors in clinical organ transplantation.", "completion": "{\"entities\": [{\"text\": \"Sirolimus\", \"type\": \"Chemical\"}, {\"text\": \"SRL\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04101", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The patient had suffered a previous episode of\" acute hepatitis of unknown origin ,\" that occurred after telithromycin usage.", "completion": "{\"entities\": [{\"text\": \"hepatitis\", \"type\": \"Disease\"}, {\"text\": \"telithromycin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04898", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Using macaque monkeys with different types of MPTP - induced parkinsonism, the current study evaluated the degree to which rate of symptom progression, symptom severity, and response to and duration of levodopa therapy may be involved in the development of LIDs.", "completion": "{\"entities\": [{\"text\": \"MPTP\", \"type\": \"Chemical\"}, {\"text\": \"parkinsonism\", \"type\": \"Disease\"}, {\"text\": \"levodopa\", \"type\": \"Chemical\"}, {\"text\": \"LIDs\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03199", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 8 %); the difference was not statistically significant.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02905", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Late, late doxorubicin cardiotoxicity.", "completion": "{\"entities\": [{\"text\": \"doxorubicin\", \"type\": \"Chemical\"}, {\"text\": \"cardiotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00846", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The most commonly reported toxic effects of capecitabine are diarrhea, nausea, vomiting, stomatitis and hand-foot syndrome.", "completion": "{\"entities\": [{\"text\": \"capecitabine\", \"type\": \"Chemical\"}, {\"text\": \"diarrhea\", \"type\": \"Disease\"}, {\"text\": \"nausea\", \"type\": \"Disease\"}, {\"text\": \"vomiting\", \"type\": \"Disease\"}, {\"text\": \"stomatitis\", \"type\": \"Disease\"}, {\"text\": \"hand-foot syndrome\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-02698", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We postulate that the mechanism of the simvastatinezetimibe - induced hepatotoxicity is the increased simvastatin exposure by ezetimibe inhibition of UGT enzymes.", "completion": "{\"entities\": [{\"text\": \"simvastatin\", \"type\": \"Chemical\"}, {\"text\": \"simvastatinezetimibe\", \"type\": \"Chemical\"}, {\"text\": \"ezetimibe\", \"type\": \"Chemical\"}, {\"text\": \"hepatotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02636", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: Using immune stainings, semiquantitative measurement was performed under the electron microscope.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01989", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It is concluded that acute amiloride administration to lithium - treated patients suffering from polydipsia and polyuria might relieve these patients but prolonged amiloride supplementation would result in elevated lithium", "completion": "{\"entities\": [{\"text\": \"amiloride\", \"type\": \"Chemical\"}, {\"text\": \"lithium\", \"type\": \"Chemical\"}, {\"text\": \"polydipsia\", \"type\": \"Disease\"}, {\"text\": \"polyuria\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02382", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 mL of gentamicin injected into the posterior sub - Tenon' s space and Group B (n = 20) had the same combination injected into the anterior sub - Tenon' s space.", "completion": "{\"entities\": [{\"text\": \"gentamicin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04372", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Radiotelemetric BP was similar between males and castrated rats on LS diet.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01013", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 75 %. There was a significant increase in CBF, although CMRO2 was unchanged, compared with pre - hypotensive values.", "completion": "{\"entities\": [{\"text\": \"hypotensive\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04160", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These results do not confirm or exclude a neuroprotective property of nimodipine", "completion": "{\"entities\": [{\"text\": \"nimodipine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03189", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It may be attributed to the structural damage to the frontal lobe", "completion": "{\"entities\": [{\"text\": \"structural damage to the frontal lobe\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04594", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These results suggest that spasm provocation tests, which use an intracoronary injection of a relatively low dose of methylergonovine, have a high sensitivity in variant angina", "completion": "{\"entities\": [{\"text\": \"spasm\", \"type\": \"Disease\"}, {\"text\": \"methylergonovine\", \"type\": \"Chemical\"}, {\"text\": \"variant angina\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02784", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Liver function tests, hepatitis B virus (HBV) serologic markers, and HBV DNA levels of the patients during follow - up were obtained from hospital file records.", "completion": "{\"entities\": [{\"text\": \"hepatitis B\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03508", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 25% bupivacaine (mean 192 mg) in the 24 - h period following upper abdominal surgery.", "completion": "{\"entities\": [{\"text\": \"bupivacaine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03941", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Patients who are given this drug regimen should be observed very carefully for early signs of nephrotoxicity.", "completion": "{\"entities\": [{\"text\": \"nephrotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02415", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 03; patients with diabetes: 0.", "completion": "{\"entities\": [{\"text\": \"diabetes\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04116", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Sixty - seven of 926 patients (7.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04404", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These data show that GnRH pulse frequency is inhibited by chronic hyperprolactinemia in a steroid - dependent manner.", "completion": "{\"entities\": [{\"text\": \"hyperprolactinemia\", \"type\": \"Disease\"}, {\"text\": \"steroid\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04363", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Our findings, showing no interaction between capsaicin treatment and attentional modulation suggest that capsaicin - induced secondary hyperalgesia and attention might affect mechanical pain", "completion": "{\"entities\": [{\"text\": \"capsaicin\", \"type\": \"Chemical\"}, {\"text\": \"hyperalgesia\", \"type\": \"Disease\"}, {\"text\": \"pain\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-05110", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: Bupropion is an effective treatment for male SD induced by SSRIs.", "completion": "{\"entities\": [{\"text\": \"Bupropion\", \"type\": \"Chemical\"}, {\"text\": \"SD\", \"type\": \"Disease\"}, {\"text\": \"SSRIs\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02634", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND / AIMS: It is still unclear what happens in the glomerulus when proteinuria starts.", "completion": "{\"entities\": [{\"text\": \"proteinuria\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04814", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We report a case of intractable hemorrhagic cystitis due to cyclophosphamide therapy for Wegener's granulomatosis.", "completion": "{\"entities\": [{\"text\": \"hemorrhagic cystitis\", \"type\": \"Disease\"}, {\"text\": \"cyclophosphamide\", \"type\": \"Chemical\"}, {\"text\": \"Wegener's granulomatosis\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04775", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The most common side - effect was diarrhoea, which resulted in cessation of therapy in 19 individuals.", "completion": "{\"entities\": [{\"text\": \"diarrhoea\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00752", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Additionally, the protective effect of verapamil on this ulcer model was evaluated.", "completion": "{\"entities\": [{\"text\": \"verapamil\", \"type\": \"Chemical\"}, {\"text\": \"ulcer\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02307", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This case illustrates the need for close vigilance in adverse drug reactions", "completion": "{\"entities\": [{\"text\": \"adverse drug reactions\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-reassigned-00507", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Fluconazole associated agranulocytosis and thrombocytopenia.", "completion": "{\"entities\": [{\"text\": \"Fluconazole\", \"type\": \"Chemical\"}, {\"text\": \"agranulocytosis\", \"type\": \"Disease\"}, {\"text\": \"thrombocytopenia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00150", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Formation of these plugs was probably due to extensive tumor necrosis at the level of the walls of the major uterine veins, which resulted in an open exchange of tumor plugs to the vascular spaces; decrease in tumor tissue coherence secondary to chemotherapy may have further contributed to the formation of tumor emboli.", "completion": "{\"entities\": [{\"text\": \"tumor\", \"type\": \"Disease\"}, {\"text\": \"necrosis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02924", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Although MHb formers are generally applied as treatments for CN poisoning, it has been proposed that a stable, long - acting MHb former could serve as a CN pretreatment.", "completion": "{\"entities\": [{\"text\": \"poisoning\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04371", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Ovariectomy of female DS had no effect on intrarenal angiotensinogen expression on either diet.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-reassigned-03019", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Delirium during fluoxetine treatment.", "completion": "{\"entities\": [{\"text\": \"Delirium\", \"type\": \"Disease\"}, {\"text\": \"fluoxetine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04858", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In conclusion, the NF - kappaB inhibitor and antioxidant PDTC protected the piriform cortex, whereas it did not affect hilar neuronal loss.", "completion": "{\"entities\": [{\"text\": \"PDTC\", \"type\": \"Chemical\"}, {\"text\": \"neuronal loss\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01308", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Fatal myeloencephalopathy due to accidental intrathecal vincristin administration: a report of two cases.", "completion": "{\"entities\": [{\"text\": \"myeloencephalopathy\", \"type\": \"Disease\"}, {\"text\": \"vincristin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03859", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Omission of fentanyl did not reduce the overall incidence of postoperative nausea and vomiting, but did reduce the incidence of vomiting and / or moderate to severe nausea prior to discharge from 20% and 17% with fentanyl and fentanyl - dexamethasone, respectively, to 5 %(P = 0.", "completion": "{\"entities\": [{\"text\": \"fentanyl\", \"type\": \"Chemical\"}, {\"text\": \"postoperative nausea and vomiting\", \"type\": \"Disease\"}, {\"text\": \"nausea\", \"type\": \"Disease\"}, {\"text\": \"vomiting\", \"type\": \"Disease\"}, {\"text\": \"dexamethasone\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-01310", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The girl died seven days, the man four weeks after intrathecal injection of vincristine.", "completion": "{\"entities\": [{\"text\": \"vincristine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03198", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 6 %) than in the placebo group (4.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01359", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The purpose of the present study was to determine if prenatal dexamethasone programmed a progressive increase in blood pressure and renal injury in rats.", "completion": "{\"entities\": [{\"text\": \"dexamethasone\", \"type\": \"Chemical\"}, {\"text\": \"increase in blood pressure\", \"type\": \"Disease\"}, {\"text\": \"renal injury\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02172", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 1 mg kg - 1 over 10 min followed by infusion of 7 micrograms kg - 1 min - 1 ), lidocaine 5 mg kg - 1 or saline for 50 min.", "completion": "{\"entities\": [{\"text\": \"lidocaine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01395", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The duration of the study was six months.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01505", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Twenty - five women were given raloxifene hydrochloride (60 mg / day) plus calcium (500 mg / day ). Age - matched controls (n = 14) were given only calcium.", "completion": "{\"entities\": [{\"text\": \"raloxifene hydrochloride\", \"type\": \"Chemical\"}, {\"text\": \"calcium\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01556", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Clinical examination and continued vigilance for neurologic deterioration after epidural steroid", "completion": "{\"entities\": [{\"text\": \"neurologic deterioration\", \"type\": \"Disease\"}, {\"text\": \"steroid\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02979", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 07 ). Support of the arm decreased tremor severity, exhaustion increased tremor severity significantly.", "completion": "{\"entities\": [{\"text\": \"tremor\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02101", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Exposure to appetite-suppressants was assessed on the basis of hospital records and standardized interview.", "completion": "{\"entities\": [{\"text\": \"appetite-suppressants\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-reassigned-04290", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 mg and droperidol 0.", "completion": "{\"entities\": [{\"text\": \"droperidol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03042", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The possibility of drug - induced aggravation should be considered whenever an unexpected increase in seizure frequency and / or new seizure types appear following a change in drug treatment.", "completion": "{\"entities\": [{\"text\": \"seizure\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00503", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: At termination of the experiments, mice underwent echocardiography, quantitation of abundance of molecular markers of CM (ventricular mRNA encoding atrial natriuretic factor [ANF] and sarcoplasmic calcium ATPase [SERCA2 ]), and determination of plasma LA.", "completion": "{\"entities\": [{\"text\": \"CM\", \"type\": \"Disease\"}, {\"text\": \"calcium\", \"type\": \"Chemical\"}, {\"text\": \"LA\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03426", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Different lobular distributions of altered hepatocyte tight junctions in rat models of intrahepatic and extrahepatic cholestasis.", "completion": "{\"entities\": [{\"text\": \"intrahepatic and extrahepatic cholestasis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02660", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Angiosarcoma was also present within pulmonary and renal arteries.", "completion": "{\"entities\": [{\"text\": \"Angiosarcoma\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04260", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After delivery of the infant, there should be no contraindication to the use of an alpha - adrenergic vasopressor such as phenylephrine to treat hypotensive patients with tachycardia", "completion": "{\"entities\": [{\"text\": \"phenylephrine\", \"type\": \"Chemical\"}, {\"text\": \"hypotensive\", \"type\": \"Disease\"}, {\"text\": \"tachycardia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02894", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the acute experiment TRI (given i.", "completion": "{\"entities\": [{\"text\": \"TRI\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02375", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Side effects of postoperative administration of methylprednisolone and gentamicin into the posterior sub - Tenon' s space.", "completion": "{\"entities\": [{\"text\": \"methylprednisolone\", \"type\": \"Chemical\"}, {\"text\": \"gentamicin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04090", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CASE SUMMARY: A 25 - year - old male patient, with a height of 175 cm and weight of 72 kg presented to Marmara University Hospital Emergency Department, Istanbul, Turkey, with 5 days' history of jaundice, malaise, nausea, and vomiting.", "completion": "{\"entities\": [{\"text\": \"jaundice\", \"type\": \"Disease\"}, {\"text\": \"nausea\", \"type\": \"Disease\"}, {\"text\": \"vomiting\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00407", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Immunohistochemical staining for NFs showed characteristic terminal clubs of axons in the borderzone of lesions.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02040", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Organelles of these cells, in particular the mitochondria (increased number and size, distinct degeneration of their matrix and cristae) and Golgi apparatus were altered.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02749", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 13 ml / min at 6 months, both P less than 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02164", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Age - related changes in ultrasound production corresponded with changes in cardiovascular variables, including baseline cardiac rate and clonidine - induced bradycardia.", "completion": "{\"entities\": [{\"text\": \"clonidine\", \"type\": \"Chemical\"}, {\"text\": \"bradycardia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01040", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A case is presented of a reversible intra-Hisian block occurring under amiodarone treatment for atrial tachycardia in a patient without clear intraventricular conduction abnormalities.", "completion": "{\"entities\": [{\"text\": \"intra-Hisian block\", \"type\": \"Disease\"}, {\"text\": \"amiodarone\", \"type\": \"Chemical\"}, {\"text\": \"atrial tachycardia\", \"type\": \"Disease\"}, {\"text\": \"intraventricular conduction abnormalities\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04906", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Serologic testing and immunologic studies were done, and a pericardial biopsy was performed.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01550", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Deep - tendon reflexes were decreased especially in the right leg.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-05227", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, apomorphine - induced reductions in striatal dopamine", "completion": "{\"entities\": [{\"text\": \"apomorphine\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04387", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Massive urinary protein excretion has been observed after conversion from calcineurin inhibitors to mammalian target of rapamycin (mToR) inhibitors, especially sirolimus, in renal transplant recipients with chronic allograft nephropathy.", "completion": "{\"entities\": [{\"text\": \"rapamycin\", \"type\": \"Chemical\"}, {\"text\": \"sirolimus\", \"type\": \"Chemical\"}, {\"text\": \"chronic allograft nephropathy\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01651", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: ECG changes and adverse events analysis.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03575", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Due to the risk of this tachycardia inducing myocardial ischemia, we would not recommend the use in elderly patients of any of the ephedrine / propofol", "completion": "{\"entities\": [{\"text\": \"tachycardia\", \"type\": \"Disease\"}, {\"text\": \"myocardial ischemia\", \"type\": \"Disease\"}, {\"text\": \"ephedrine\", \"type\": \"Chemical\"}, {\"text\": \"propofol\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02786", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 8 months (range 5 - 27) were enrolled in this study.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03319", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: v .) n = 18; controls, saline i.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03969", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Vegetarians may also take creatine to replace what they are not consuming from meat, fish, and other animal products.", "completion": "{\"entities\": [{\"text\": \"creatine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03884", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: c .) and amphetamine (2 mg / kg s.", "completion": "{\"entities\": [{\"text\": \"amphetamine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05225", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: By contrast, apomorphine - induced locomotion was more prominent in the novel exploratory box.", "completion": "{\"entities\": [{\"text\": \"apomorphine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01770", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The renal function of 74 children with malignant mesenchymal tumors in complete remission and who have received the same ifosfamide chemotherapy protocol (International Society of Pediatric Oncology Malignant Mesenchymal Tumor Study 84 [SIOP MMT 84 ]) were studied 1 year after the completion of treatment.", "completion": "{\"entities\": [{\"text\": \"malignant mesenchymal tumors\", \"type\": \"Disease\"}, {\"text\": \"ifosfamide\", \"type\": \"Chemical\"}, {\"text\": \"Malignant Mesenchymal Tumor\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00036", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: NX caused an additive deterioration in GFR which, however, was ameliorated by HP.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02774", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Adequate fracture reduction was obtained in 111 of the children.", "completion": "{\"entities\": [{\"text\": \"fracture\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00788", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: To address the potential confounding effects of the cannabis use of the ecstasy using group, a second analysis included 14 previously tested cannabis users (Nestor, L ., Roberts, G ., Garavan, H ., Hester, R ., 2008.", "completion": "{\"entities\": [{\"text\": \"cannabis\", \"type\": \"Chemical\"}, {\"text\": \"ecstasy\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02073", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Two groups of 22 similar patients were studied: one group received 6 mL prilocaine 2 %; and the other received 3 mL bupivacaine 0.", "completion": "{\"entities\": [{\"text\": \"prilocaine\", \"type\": \"Chemical\"}, {\"text\": \"bupivacaine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03532", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We investigated the diagnostic value of cTnI and cTnT for the diagnosis of myocardial damage in a rat model of doxorubicin (DOX )- induced cardiomyopathy, and we examined the relationship between serial cTnI and cTnT with the development of cardiac disorders monitored by echocardiography and histological examinations in this model.", "completion": "{\"entities\": [{\"text\": \"myocardial damage\", \"type\": \"Disease\"}, {\"text\": \"doxorubicin\", \"type\": \"Chemical\"}, {\"text\": \"DOX\", \"type\": \"Chemical\"}, {\"text\": \"cardiomyopathy\", \"type\": \"Disease\"}, {\"text\": \"cardiac disorders\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-03028", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The majority of these aneurysms were smaller than those of the control group (8 +/- 6.", "completion": "{\"entities\": [{\"text\": \"aneurysms\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03179", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: No significant changes in diastolic blood pressure, pulse rate and basal tear secretion were noted.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02143", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After recovery from hypertension, the activity of (Na, K )- ATPase increased, due to higher affinity of the ATP - binding site, as revealed from the lowered Km value for ATP.", "completion": "{\"entities\": [{\"text\": \"hypertension\", \"type\": \"Disease\"}, {\"text\": \"Na\", \"type\": \"Chemical\"}, {\"text\": \"K\", \"type\": \"Chemical\"}, {\"text\": \"ATP\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01911", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: One patient was prematurely discontinued from the study for severe headache and abdominal pain", "completion": "{\"entities\": [{\"text\": \"headache\", \"type\": \"Disease\"}, {\"text\": \"abdominal pain\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04355", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, this difference reached statistical significance only with regard to reported pain sensation (P = 0.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02152", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Bromocriptine - induced hypotension was unaffected by isoproterenol pretreatment, while tachycardia was reversed to significant bradycardia, an effect that was partly reduced by i.", "completion": "{\"entities\": [{\"text\": \"Bromocriptine\", \"type\": \"Chemical\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}, {\"text\": \"isoproterenol\", \"type\": \"Chemical\"}, {\"text\": \"tachycardia\", \"type\": \"Disease\"}, {\"text\": \"bradycardia\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-02064", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: For one severely affected worker liver biopsy and immunohistochemical stainings for the presence of trifluoroacetyl protein adducts were done.", "completion": "{\"entities\": [{\"text\": \"trifluoroacetyl\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04872", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 2 cigarettes per day at baseline.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03958", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Lone atrial fibrillation associated with creatine monohydrate supplementation.", "completion": "{\"entities\": [{\"text\": \"atrial fibrillation\", \"type\": \"Disease\"}, {\"text\": \"creatine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00001", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In unanesthetized, spontaneously hypertensive rats the decrease in blood pressure and heart rate produced by intravenous clonidine, 5 to 20 micrograms / kg, was inhibited or reversed by nalozone, 0.", "completion": "{\"entities\": [{\"text\": \"hypertensive\", \"type\": \"Disease\"}, {\"text\": \"clonidine\", \"type\": \"Chemical\"}, {\"text\": \"nalozone\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00191", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: On the mechanisms of the development of tolerance to the muscular rigidity produced by morphine in rats.", "completion": "{\"entities\": [{\"text\": \"muscular rigidity\", \"type\": \"Disease\"}, {\"text\": \"morphine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01857", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Inhibition of immunoreactive corticotropin - releasing factor secretion into the hypophysial - portal circulation by delayed glucocorticoid feedback.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01541", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The following case is a report of cauda equina syndrome possibly caused by epidural injection of triamcinolone and bupivacaine.", "completion": "{\"entities\": [{\"text\": \"cauda equina syndrome\", \"type\": \"Disease\"}, {\"text\": \"triamcinolone\", \"type\": \"Chemical\"}, {\"text\": \"bupivacaine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-reassigned-03593", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Patterns of sulfadiazine acute nephrotoxicity.", "completion": "{\"entities\": [{\"text\": \"sulfadiazine\", \"type\": \"Chemical\"}, {\"text\": \"acute nephrotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04184", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Almost certainly, nicotine via its hemodynamic effects contributes to acute cardiovascular events, although current evidence suggests that the effects of nicotine are much less important than are the prothrombotic effects of cigarette smoking or the effects of carbon monoxide.", "completion": "{\"entities\": [{\"text\": \"nicotine\", \"type\": \"Chemical\"}, {\"text\": \"carbon monoxide\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01321", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Akathisia was defined as either a spontaneous report of restlessness or agitation or a change of 2 or more in the patient - reported akathisia rating scale and a change of at least 1 in the investigator - observed akathisia rating scale.", "completion": "{\"entities\": [{\"text\": \"agitation\", \"type\": \"Disease\"}, {\"text\": \"akathisia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01938", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, age was seen to interfere with the responses exhibited by the young and old rats.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-05043", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This paper presents the results of treating IST by intratympanic instillation of lignocaine (lidocaine) 2 per cent through a grommet, for five weekly courses.", "completion": "{\"entities\": [{\"text\": \"IST\", \"type\": \"Disease\"}, {\"text\": \"lignocaine\", \"type\": \"Chemical\"}, {\"text\": \"lidocaine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01384", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Acromegaly is an endocrine disorder caused by chronic excessive growth hormone secretion from the anterior pituitary gland.", "completion": "{\"entities\": [{\"text\": \"Acromegaly\", \"type\": \"Disease\"}, {\"text\": \"endocrine disorder\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04351", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Toxic peripheral neuropathy is still a significant limiting factor for chemotherapy with paclitaxel (PAC ), although glutamate and its closely related amino acid glutamine were claimed to ameliorate PAC neurotoxicity.", "completion": "{\"entities\": [{\"text\": \"peripheral neuropathy\", \"type\": \"Disease\"}, {\"text\": \"paclitaxel\", \"type\": \"Chemical\"}, {\"text\": \"PAC\", \"type\": \"Chemical\"}, {\"text\": \"glutamate\", \"type\": \"Chemical\"}, {\"text\": \"amino acid\", \"type\": \"Chemical\"}, {\"text\": \"glutamine\", \"type\": \"Chemical\"}, {\"text\": \"neurotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 7}
{"ref": "bc5cdr-train-03277", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Vascular eNOS mRNA was assessed by semi - quantitative reverse transcription - polymerase chain reaction.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-reassigned-00001", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A series of six cases.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02958", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: OBJECTIVE: To study tremor side effects of salbutamol an easily applicable, quick and low - priced method is needed.", "completion": "{\"entities\": [{\"text\": \"tremor\", \"type\": \"Disease\"}, {\"text\": \"salbutamol\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05047", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Patients should be warned about the side effects of vertigo and vomiting, which subsides gradually with every new instillation, and that the tinnitus", "completion": "{\"entities\": [{\"text\": \"vertigo\", \"type\": \"Disease\"}, {\"text\": \"vomiting\", \"type\": \"Disease\"}, {\"text\": \"tinnitus\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00940", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Prazosin exerts its antihypertensive effects through vasodilatation caused by selective blockade of postsynaptic alpha - 1 adrenergic receptors.", "completion": "{\"entities\": [{\"text\": \"Prazosin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00057", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Eleven of the cocaine abusers and none of the controls had ECG evidence of significant myocardial injury defined as myocardial infarction, ischemia, and bundle branch block", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"myocardial injury\", \"type\": \"Disease\"}, {\"text\": \"myocardial infarction\", \"type\": \"Disease\"}, {\"text\": \"ischemia\", \"type\": \"Disease\"}, {\"text\": \"bundle branch block\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-05191", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: To better understand the utility of GLEPP1 as a marker of glomerular injury, the amount and distribution of GLEPP1 protein and mRNA were examined by immunohistochemistry, Western blot and RNase protection assay in a model of podocyte injury in the rat.", "completion": "{\"entities\": [{\"text\": \"glomerular injury\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01986", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: At 12 h, all the tissues showed a slight increase in lithium levels.", "completion": "{\"entities\": [{\"text\": \"lithium\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04248", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We describe 4 patients in whom hyperkalemia ranging from 6.", "completion": "{\"entities\": [{\"text\": \"hyperkalemia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00259", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: There is a male preponderance and the peak incidence is in the fourth decade.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02240", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05 ), suggesting the partial involvement of the opioidergic system in the synergism observed.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03763", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This approach allowed investigating the efficacy of alpha-lipoic acid in preventing axonal damage and apoptosis and the function and ultrastructural morphology of mitochondria after exposure to toxic agents and alpha-lipoic acid.", "completion": "{\"entities\": [{\"text\": \"alpha-lipoic acid\", \"type\": \"Chemical\"}, {\"text\": \"axonal damage\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02996", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Severe thrombocytopenia and haemolytic anaemia associated with ciprofloxacin: a case report with fatal outcome.", "completion": "{\"entities\": [{\"text\": \"thrombocytopenia\", \"type\": \"Disease\"}, {\"text\": \"haemolytic anaemia\", \"type\": \"Disease\"}, {\"text\": \"ciprofloxacin\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03003", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: No signs of bone marrow depression were found.", "completion": "{\"entities\": [{\"text\": \"bone marrow depression\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04505", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: MR imaging with quantitative diffusion mapping of tacrolimus - induced neurotoxicity in organ transplant patients.", "completion": "{\"entities\": [{\"text\": \"tacrolimus\", \"type\": \"Chemical\"}, {\"text\": \"neurotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02100", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thirty - five patients with primary pulmonary hypertension and 85 matched controls were recruited over 32 months (1992 - 1994) in Belgium.", "completion": "{\"entities\": [{\"text\": \"primary pulmonary hypertension\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00387", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: min - 1 of PGE1 (15 patients ), or 10 micrograms.", "completion": "{\"entities\": [{\"text\": \"PGE1\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00720", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 89 ), including isolated - HIT patients who later developed thrombosis within 30 d (n = 8, 1.", "completion": "{\"entities\": [{\"text\": \"HIT\", \"type\": \"Disease\"}, {\"text\": \"thrombosis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04690", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The most common side effects attributable to the AraG included Grade 2 and 3 sensory and motor neuropathy and musculoskeletal pain.", "completion": "{\"entities\": [{\"text\": \"AraG\", \"type\": \"Chemical\"}, {\"text\": \"neuropathy\", \"type\": \"Disease\"}, {\"text\": \"musculoskeletal pain\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02052", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Endophthalmitis resolved with improvement in visual acuity to 6 / 24 at three months.", "completion": "{\"entities\": [{\"text\": \"Endophthalmitis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03696", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: To date, 23 men with a median age of 50 years and good performance status have entered the trial.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02405", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 1 %(4 of 78 patients) with iopamidol and 13.", "completion": "{\"entities\": [{\"text\": \"iopamidol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01574", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A common risk factor appears to be presence of pre - existing chronic renal damage.", "completion": "{\"entities\": [{\"text\": \"chronic renal damage\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03770", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Atrial fibrillation is associated with substantial morbidity and mortality.", "completion": "{\"entities\": [{\"text\": \"Atrial fibrillation\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01830", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Dipyridamole significantly increased coronary blood flow before and after 7.", "completion": "{\"entities\": [{\"text\": \"Dipyridamole\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04218", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After one year of treatment, five of the remaining nine patients showed either partial (n = 3) or complete (n = 2) gall stone dissolution, suggesting that their stones were cholesterol rich.", "completion": "{\"entities\": [{\"text\": \"gall stone\", \"type\": \"Disease\"}, {\"text\": \"cholesterol\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02898", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It may be concluded that, like other tricyclic antidepressants studied previously, TRI given repeatedly increases the responsiveness of brain dopamine D2 and D3 (locomotor activity but not stereotypy) as well as alpha1 - adrenergic receptors to their agonists.", "completion": "{\"entities\": [{\"text\": \"antidepressants\", \"type\": \"Chemical\"}, {\"text\": \"TRI\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03381", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Two patients treated with parenteral paramethasone (Triniol) and dexamethasone (Sedionbel) are described.", "completion": "{\"entities\": [{\"text\": \"paramethasone\", \"type\": \"Chemical\"}, {\"text\": \"dexamethasone\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02358", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We report the case of a 63 - year - old female who was treated with methylphenidate due to hyperactivity and suffered from multiple ischaemic strokes.", "completion": "{\"entities\": [{\"text\": \"methylphenidate\", \"type\": \"Chemical\"}, {\"text\": \"hyperactivity\", \"type\": \"Disease\"}, {\"text\": \"ischaemic strokes\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00970", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Two patients with type II diabetes mellitus developed an acute hepatitis-like syndrome soon after initiation of glyburide therapy.", "completion": "{\"entities\": [{\"text\": \"type II diabetes mellitus\", \"type\": \"Disease\"}, {\"text\": \"acute hepatitis-like syndrome\", \"type\": \"Disease\"}, {\"text\": \"glyburide\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02832", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Head - up tilt caused systolic orthostatic hypotension which was marked in six of 20 PD patients on selegiline, one of whom lost consciousness with unrecordable blood pressures.", "completion": "{\"entities\": [{\"text\": \"systolic orthostatic hypotension\", \"type\": \"Disease\"}, {\"text\": \"PD\", \"type\": \"Disease\"}, {\"text\": \"selegiline\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00348", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: For both experiments the drug intake led to significant increases in PRL secretion, acting preferentially on tonic secretion as pulse amplitude and frequency did not differ significantly from corresponding control values.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02543", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The average temporal delay between papaverine and the onset of an adverse BAEP change was 5 min.", "completion": "{\"entities\": [{\"text\": \"papaverine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01232", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The estimated incidence of angioedema during angiotensin-converting enzyme (ACE) inhibitor", "completion": "{\"entities\": [{\"text\": \"angioedema\", \"type\": \"Disease\"}, {\"text\": \"angiotensin-converting enzyme (ACE) inhibitor\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03216", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The case of a schizophrenic patient is reported to illustrate massive rhabdomyolysis and subsequent acute renal failure following molindone administration.", "completion": "{\"entities\": [{\"text\": \"schizophrenic\", \"type\": \"Disease\"}, {\"text\": \"rhabdomyolysis\", \"type\": \"Disease\"}, {\"text\": \"acute renal failure\", \"type\": \"Disease\"}, {\"text\": \"molindone\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02202", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This study assessed the ability of IH636 grape seed proanthocyanidin extract (GSPE) to prevent acetaminophen (AAP )- induced nephrotoxicity, amiodarone (AMI )- induced lung toxicity, and doxorubicin (DOX )- induced cardiotoxicity in mice.", "completion": "{\"entities\": [{\"text\": \"IH636 grape seed proanthocyanidin extract\", \"type\": \"Chemical\"}, {\"text\": \"GSPE\", \"type\": \"Chemical\"}, {\"text\": \"acetaminophen\", \"type\": \"Chemical\"}, {\"text\": \"AAP\", \"type\": \"Chemical\"}, {\"text\": \"nephrotoxicity\", \"type\": \"Disease\"}, {\"text\": \"amiodarone\", \"type\": \"Chemical\"}, {\"text\": \"AMI\", \"type\": \"Chemical\"}, {\"text\": \"lung toxicity\", \"type\": \"Disease\"}, {\"text\": \"doxorubicin\", \"type\": \"Chemical\"}, {\"text\": \"DOX\", \"type\": \"Chemical\"}, {\"text\": \"cardiotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 11}
{"ref": "bc5cdr-train-02312", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Blood flow was monitored in arteries of the exposed cranial dura mater and the parietal cortex using laser Doppler flowmetry.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00500", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Combined antiretroviral therapy causes cardiomyopathy and elevates plasma lactate in transgenic AIDS mice.", "completion": "{\"entities\": [{\"text\": \"cardiomyopathy\", \"type\": \"Disease\"}, {\"text\": \"lactate\", \"type\": \"Chemical\"}, {\"text\": \"AIDS\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00765", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The aim of this study was to investigate whether autophagy was involved in the progression of heart failure induced by adriamycin, so that we can develop a novel treatment strategy for heart failure.", "completion": "{\"entities\": [{\"text\": \"heart failure\", \"type\": \"Disease\"}, {\"text\": \"adriamycin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02712", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: When they do occur they are often unrecognized because of denial but when significant may pose a risk to both the mother and her fetus.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00685", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 164 patients (mean age +/- standard deviation [SD] 81.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02246", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We report a case of a 51 - year - old man who developed severe, disabling negative myoclonus of the upper and lower extremities after the infusion of ifosfamide for plasmacytoma.", "completion": "{\"entities\": [{\"text\": \"myoclonus\", \"type\": \"Disease\"}, {\"text\": \"ifosfamide\", \"type\": \"Chemical\"}, {\"text\": \"plasmacytoma\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00308", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Increased density and / or size and PRL content were indicated for the majority of the PRL cell population in both types of separation protocols.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02185", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: With the more widespread application of tacrolimus in organ transplantation, tacrolimus - associated TMA has also been recognized.", "completion": "{\"entities\": [{\"text\": \"tacrolimus\", \"type\": \"Chemical\"}, {\"text\": \"TMA\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05212", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The fact that 5 of the 6 patients who received concurrent calcium", "completion": "{\"entities\": [{\"text\": \"calcium\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03349", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thus, gentamicin was associated with renal failure more than three times as often as was tobramycin", "completion": "{\"entities\": [{\"text\": \"gentamicin\", \"type\": \"Chemical\"}, {\"text\": \"renal failure\", \"type\": \"Disease\"}, {\"text\": \"tobramycin\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01271", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The authors present a 10 - year - old boy chronically treated with lisinopril, an angiotensin converting enzyme inhibitor, to control hypertension who developed hypotension following the addition of tizanidine, an alpha - 2 agonist, for the treatment of spasticity.", "completion": "{\"entities\": [{\"text\": \"lisinopril\", \"type\": \"Chemical\"}, {\"text\": \"angiotensin\", \"type\": \"Chemical\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}, {\"text\": \"tizanidine\", \"type\": \"Chemical\"}, {\"text\": \"spasticity\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-04370", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: HS diet for 4 wk increased renal cortical angiotensinogen mRNA and protein only in male DS, which was prevented by castration.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01109", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Skin tests with AX were positive in 34 (63 %) patients.", "completion": "{\"entities\": [{\"text\": \"AX\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01590", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: Inhibition of cardiac sympathetic tone represents an important strategy for treatment of cardiovascular disease, including arrhythmia, coronary heart disease, and chronic heart failure.", "completion": "{\"entities\": [{\"text\": \"cardiovascular disease\", \"type\": \"Disease\"}, {\"text\": \"arrhythmia\", \"type\": \"Disease\"}, {\"text\": \"coronary heart disease\", \"type\": \"Disease\"}, {\"text\": \"heart failure\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00182", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Analyses of a blood sample revealed unusually high plasma concentrations of metoprolol (greater than 3000 ng / ml) and diltiazem (526 ng / ml ). The patient recovered within 1 week following discontinuation of antianginal therapy.", "completion": "{\"entities\": [{\"text\": \"metoprolol\", \"type\": \"Chemical\"}, {\"text\": \"diltiazem\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00445", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: Although the prevalence of nonsmall cell lung carcinoma (NSCLC) is high among elderly patients, few data are available regarding the efficacy and toxicity of chemotherapy in this group of patients.", "completion": "{\"entities\": [{\"text\": \"nonsmall cell lung carcinoma\", \"type\": \"Disease\"}, {\"text\": \"NSCLC\", \"type\": \"Disease\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01107", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Anaphylaxis was seen in 37 patients (69 %), the other 17 (31 %) having urticaria and / or angioedema.", "completion": "{\"entities\": [{\"text\": \"Anaphylaxis\", \"type\": \"Disease\"}, {\"text\": \"urticaria\", \"type\": \"Disease\"}, {\"text\": \"angioedema\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03851", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The similarities between the effects of structural lesions and pharmacological depression of the brain stem reticular formation are discussed.", "completion": "{\"entities\": [{\"text\": \"depression\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04499", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Neither L-arginine transport into mononuclear cells (placebo vs active, 26.", "completion": "{\"entities\": [{\"text\": \"L-arginine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02167", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We have examined the effect of systemic administration of ketamine and lidocaine on brush - evoked (dynamic) pain and punctate - evoked (static) hyperalgesia induced by capsaicin.", "completion": "{\"entities\": [{\"text\": \"ketamine\", \"type\": \"Chemical\"}, {\"text\": \"lidocaine\", \"type\": \"Chemical\"}, {\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"hyperalgesia\", \"type\": \"Disease\"}, {\"text\": \"capsaicin\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-05223", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In mice, apomorphine produced qualitatively different responses under novel conditions when compared to those behaviors elicited in the home test cage.", "completion": "{\"entities\": [{\"text\": \"apomorphine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02010", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: of a combination of 3 drugs: 6 mg.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00454", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The overall response rate was 26 %(95% confidence interval, 15 - 41 %). Two patients attained a complete response (4 %) and 11 patients (22 %) achieved a partial response.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03134", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Amiodarone and atazanavir are recognized CYP3A4 inhibitors.", "completion": "{\"entities\": [{\"text\": \"Amiodarone\", \"type\": \"Chemical\"}, {\"text\": \"atazanavir\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05045", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In one patient, the tinnitus was almost completely abolished, but in all the nine patients the decompensated tinnitus changed to a compensated one.", "completion": "{\"entities\": [{\"text\": \"tinnitus\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00803", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Antituberculosis therapy - induced acute liver failure: magnitude, profile, prognosis, and predictors of outcome.", "completion": "{\"entities\": [{\"text\": \"Antituberculosis\", \"type\": \"Chemical\"}, {\"text\": \"acute liver failure\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03452", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Regular audiologic evaluation is imperative in all thalassemic patients so that early changes may be recognized and treatment may be judiciously adjusted in order to prevent or reverse hearing impairment", "completion": "{\"entities\": [{\"text\": \"thalassemic\", \"type\": \"Disease\"}, {\"text\": \"hearing impairment\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01199", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Attempts to resuscitate the patient were not successful.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00197", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In a further series of experiments, haloperidol (0.", "completion": "{\"entities\": [{\"text\": \"haloperidol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04317", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Neonatal pyridoxine responsive convulsions due to isoniazid therapy.", "completion": "{\"entities\": [{\"text\": \"pyridoxine\", \"type\": \"Chemical\"}, {\"text\": \"convulsions\", \"type\": \"Disease\"}, {\"text\": \"isoniazid\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01559", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: In a population - based study in 513 naturally postmenopausal women aged 54 - 67 years, we studied the association between self - reported intramuscularly administered high - dose estrogen - testosterone therapy (estradiol- and testosterone esters) and aortic atherosclerosis.", "completion": "{\"entities\": [{\"text\": \"estrogen\", \"type\": \"Chemical\"}, {\"text\": \"testosterone\", \"type\": \"Chemical\"}, {\"text\": \"estradiol- and testosterone esters\", \"type\": \"Chemical\"}, {\"text\": \"atherosclerosis\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03917", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: g ., nephrotoxicity, ototoxicity, and neurotoxicity) have limited its use as a treatment for breast carcinoma.", "completion": "{\"entities\": [{\"text\": \"nephrotoxicity\", \"type\": \"Disease\"}, {\"text\": \"ototoxicity\", \"type\": \"Disease\"}, {\"text\": \"neurotoxicity\", \"type\": \"Disease\"}, {\"text\": \"breast carcinoma\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04142", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Patients who develop ESRD have a higher preoperative and 1 - year serum creatinine and are more likely to have hepatorenal syndrome.", "completion": "{\"entities\": [{\"text\": \"ESRD\", \"type\": \"Disease\"}, {\"text\": \"creatinine\", \"type\": \"Chemical\"}, {\"text\": \"hepatorenal syndrome\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00178", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: d .) had been initiated.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02957", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Tremor side effects of salbutamol, quantified by a laser pointer technique.", "completion": "{\"entities\": [{\"text\": \"Tremor\", \"type\": \"Disease\"}, {\"text\": \"salbutamol\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04492", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Hydrocortisone acetate (50 mg) was given orally every 6 hours for 24 hours after a 5 - day fixed - salt diet (150 mmol / d ). Crossover studies were performed 2 weeks apart.", "completion": "{\"entities\": [{\"text\": \"Hydrocortisone acetate\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02096", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This case documents acute drug - related vanishing bile duct syndrome in the pediatric age group and suggests shared immune mechanisms in the pathogenesis of both Stevens-Johnson syndrome and vanishing bile duct syndrome", "completion": "{\"entities\": [{\"text\": \"vanishing bile duct syndrome\", \"type\": \"Disease\"}, {\"text\": \"Stevens-Johnson syndrome\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04348", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thus, interference with the central venous infusion by the dialysis catheter was suspected.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03305", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: For the 60 patients who completed phase A, standard - dose haloperidol was efficacious and superior to both low - dose haloperidol and placebo for scores on the Brief Psychiatric Rating Scale psychosis factor and on psychomotor agitation.", "completion": "{\"entities\": [{\"text\": \"haloperidol\", \"type\": \"Chemical\"}, {\"text\": \"psychosis\", \"type\": \"Disease\"}, {\"text\": \"psychomotor agitation\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01573", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Because sirolimus does not share the vasomotor renal adverse effects exhibited by calcineurin inhibitors, it has been designated a' non - nephrotoxic drug '. However, clinical reports suggest that, under some circumstances, sirolimus is associated with proteinuria and acute renal dysfunction.", "completion": "{\"entities\": [{\"text\": \"sirolimus\", \"type\": \"Chemical\"}, {\"text\": \"nephrotoxic\", \"type\": \"Disease\"}, {\"text\": \"proteinuria\", \"type\": \"Disease\"}, {\"text\": \"acute renal dysfunction\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02060", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: Hydrochlorofluorocarbons (HCFCs) are used increasingly in industry as substitutes for ozone - depleting chlorofluorocarbons (CFCs ). Limited studies in animals indicate potential hepatotoxicity of some of these compounds.", "completion": "{\"entities\": [{\"text\": \"Hydrochlorofluorocarbons\", \"type\": \"Chemical\"}, {\"text\": \"chlorofluorocarbons\", \"type\": \"Chemical\"}, {\"text\": \"HCFCs\", \"type\": \"Chemical\"}, {\"text\": \"CFCs\", \"type\": \"Chemical\"}, {\"text\": \"ozone\", \"type\": \"Chemical\"}, {\"text\": \"hepatotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-02363", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: PURPOSE: To evaluate the frequency, severity and preventability of warfarin - induced cerebral haemorrhages due to warfarin and warfarin - drug interactions in patients living in the county of Osterg tland, Sweden.", "completion": "{\"entities\": [{\"text\": \"warfarin\", \"type\": \"Chemical\"}, {\"text\": \"cerebral haemorrhages\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05029", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In contrast, in the nitrendipine - treated group albuminuria increased from 12.", "completion": "{\"entities\": [{\"text\": \"nitrendipine\", \"type\": \"Chemical\"}, {\"text\": \"albuminuria\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03443", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Subjects were receiving desferrioxamine (DFO) chelation treatment with a mean daily dose of 50 - 60 mg / kg, 5 - 6 days a week during the first six years of the study, which was then reduced to 40 - 50 mg / kg for the following eight years.", "completion": "{\"entities\": [{\"text\": \"desferrioxamine\", \"type\": \"Chemical\"}, {\"text\": \"DFO\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02330", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A gene cluster comprises the alpha3, alpha5 and beta4 subunits, which coassemble to form functional receptors.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02122", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The extension of hemolysis is variable with erythrocyte samples, but 12.", "completion": "{\"entities\": [{\"text\": \"hemolysis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00155", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Assessments of marital happiness and depressed mood were also made using the CES - D and the Azrin Marital Happiness Scale (AMHS ). Sexual dysfunctions were found to be common among patients and controls, the majority in both groups reporting one or more dysfunctions.", "completion": "{\"entities\": [{\"text\": \"depressed mood\", \"type\": \"Disease\"}, {\"text\": \"Sexual dysfunctions\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01528", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The extent of memory improvement evoked by DCE was 23% at the dose of 200 mg / kg and 35% at the dose of 400 mg / kg in young mice using elevated plus maze.", "completion": "{\"entities\": [{\"text\": \"DCE\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02277", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The extent of silver - stained CA3 and CA1 hippocampal neurons was evaluated 2 days after SE.", "completion": "{\"entities\": [{\"text\": \"silver\", \"type\": \"Chemical\"}, {\"text\": \"SE\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00141", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 3 microgram / kg / min) were observed, which is in contrast to comparable hypotension induced by hydralazine or nitroglycerin.", "completion": "{\"entities\": [{\"text\": \"hypotension\", \"type\": \"Disease\"}, {\"text\": \"hydralazine\", \"type\": \"Chemical\"}, {\"text\": \"nitroglycerin\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00320", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Such disparity suggests an inhibition of creatine phosphokinase.", "completion": "{\"entities\": [{\"text\": \"creatine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02840", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Systematic investigations of the human capacity to remember sensory features of experimental pain are sparse.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00802", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This is the first report to measure plasma argatroban concentration in the context of CPB and extended coagulopathy", "completion": "{\"entities\": [{\"text\": \"argatroban\", \"type\": \"Chemical\"}, {\"text\": \"coagulopathy\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00705", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: She noticed hoarseness and distally accentuated motor and sensory dysfunction after she had recovered from this state.", "completion": "{\"entities\": [{\"text\": \"hoarseness\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02461", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In this study, long - term cardiac transplant patients were switched from cyclosporine to Srl - based IS.", "completion": "{\"entities\": [{\"text\": \"cyclosporine\", \"type\": \"Chemical\"}, {\"text\": \"Srl\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04453", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 8 kb mtDNA deletion but with no differences in frequency or quantity in the control and experimental groups.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00276", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Dothiepin thus was found to be an effective antidepressant drug associated with fewer side effects than amitriptyline in the treatment of depressed", "completion": "{\"entities\": [{\"text\": \"Dothiepin\", \"type\": \"Chemical\"}, {\"text\": \"antidepressant\", \"type\": \"Chemical\"}, {\"text\": \"amitriptyline\", \"type\": \"Chemical\"}, {\"text\": \"depressed\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04564", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: An elderly patient treated with low dose Desipramine developed a delirium while her plasma level was in the\" subtherapeutic\" range.", "completion": "{\"entities\": [{\"text\": \"Desipramine\", \"type\": \"Chemical\"}, {\"text\": \"delirium\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02124", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Despite inducing extensive erythrocyte lysis, TAM does not shift the osmotic fragility curves of erythrocytes.", "completion": "{\"entities\": [{\"text\": \"TAM\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00237", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Dizziness was less marked than sedation, but increased with the dose.", "completion": "{\"entities\": [{\"text\": \"Dizziness\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04295", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This led us to hypothesize that a metabolite of cocaine may be responsible for some of those delayed sequelae.", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05115", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In this study, cancer patients who have solid and hematological malignancies with chronic HBV infection received the antiviral agent lamivudine prior and during CT compared with historical control group who did not receive lamivudine.", "completion": "{\"entities\": [{\"text\": \"cancer\", \"type\": \"Disease\"}, {\"text\": \"hematological malignancies\", \"type\": \"Disease\"}, {\"text\": \"HBV infection\", \"type\": \"Disease\"}, {\"text\": \"lamivudine\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04641", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Serum samples from the first and second days contained 3.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00163", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A Cambodian woman with hemoglobin E trait (AE) and leprosy developed a Heinz body hemolytic anemia while taking a dose of dapsone (50 mg / day) not usually associated with clinical hemolysis.", "completion": "{\"entities\": [{\"text\": \"leprosy\", \"type\": \"Disease\"}, {\"text\": \"hemolytic anemia\", \"type\": \"Disease\"}, {\"text\": \"dapsone\", \"type\": \"Chemical\"}, {\"text\": \"hemolysis\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04286", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thirty - two healthy young volunteers were randomly allocated to four different groups.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01510", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 01 ), and a significant increase in tPA antigen concentrations (25% change, P < 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04097", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 3 mg / dL ); and albumin, 4.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01311", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Clinically, the onset was characterized by the signs of opistothonus, sensory and motor dysfunction and ascending paralysis.", "completion": "{\"entities\": [{\"text\": \"opistothonus, sensory and motor dysfunction\", \"type\": \"Disease\"}, {\"text\": \"paralysis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00256", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Because of the extreme toxicity of vitamin D3 in pregnant Jersey cows and the low margin of safety between doses of vitamin D3 that prevent milk fever and doses that induce milk fever, we concluded that vitamin D3 cannot be used practically to prevent milk fever", "completion": "{\"entities\": [{\"text\": \"toxicity\", \"type\": \"Disease\"}, {\"text\": \"vitamin D3\", \"type\": \"Chemical\"}, {\"text\": \"milk fever\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01256", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: once daily) aggressive behavior of adult male and female Wistar rats obtained from the same breeder was studied in two consecutive sets.", "completion": "{\"entities\": [{\"text\": \"aggressive behavior\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00170", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of metoprolol, propafenone, diltiazem, and sparteine.", "completion": "{\"entities\": [{\"text\": \"metoprolol\", \"type\": \"Chemical\"}, {\"text\": \"propafenone\", \"type\": \"Chemical\"}, {\"text\": \"diltiazem\", \"type\": \"Chemical\"}, {\"text\": \"sparteine\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03547", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 and 12 mg / kg in comparison with baseline (p < 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04985", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 9 min ). Assessing their overall satisfaction, 89.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-05046", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We suggest this mode of treatment for patients that were previously treated by drugs, acupuncture and biofeedback, with disappointing results.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03641", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Sulfonamides were associated with anencephaly (adjusted OR [AOR ]= 3.", "completion": "{\"entities\": [{\"text\": \"Sulfonamides\", \"type\": \"Chemical\"}, {\"text\": \"anencephaly\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01289", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In contrast to the protection provided by the putative antagonists, the well - characterized sigma receptor agonist di-o-tolylguanidine (DTG) and the novel sigma receptor agonist BD1031 (3R-1-[2-(3,4-dichlorophenyl)ethyl]-1,4-diazabicyclo[4.3.0]nonane) each worsened the behavioral toxicity of cocaine.", "completion": "{\"entities\": [{\"text\": \"di-o-tolylguanidine\", \"type\": \"Chemical\"}, {\"text\": \"DTG\", \"type\": \"Chemical\"}, {\"text\": \"BD1031\", \"type\": \"Chemical\"}, {\"text\": \"3R-1-[2-(3,4-dichlorophenyl)ethyl]-1,4-diazabicyclo[4.3.0]nonane\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-00618", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Using functional magnetic resonance imaging (fMRI) in normal volunteers, we studied the gabapentin - induced modulation of brain activity in response to nociceptive mechanical stimulation of normal skin and capsaicin - induced secondary hyperalgesia.", "completion": "{\"entities\": [{\"text\": \"gabapentin\", \"type\": \"Chemical\"}, {\"text\": \"capsaicin\", \"type\": \"Chemical\"}, {\"text\": \"secondary hyperalgesia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-reassigned-00465", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 6 years after the end of treatment.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03419", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: changes increased as trough - concentrations rose, 5 patients had lumbar puncture.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-reassigned-04637", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 4 - fold reduction (P < 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00493", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Caffeine - induced cardiac arrhythmia: an unrecognised danger of healthfood products.", "completion": "{\"entities\": [{\"text\": \"Caffeine\", \"type\": \"Chemical\"}, {\"text\": \"cardiac arrhythmia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02916", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Is the treatment of scabies hazardous ? Treatment for scabies is usually initiated by general practitioners; most consider lindane (gamma benzene hexachloride) the treatment of choice.", "completion": "{\"entities\": [{\"text\": \"scabies\", \"type\": \"Disease\"}, {\"text\": \"lindane\", \"type\": \"Chemical\"}, {\"text\": \"gamma benzene hexachloride\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00785", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Learning and memory deficits in ecstasy users and their neural correlates during a face - learning task.", "completion": "{\"entities\": [{\"text\": \"Learning and memory deficits\", \"type\": \"Disease\"}, {\"text\": \"ecstasy\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00845", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It has shown promising results alone or in combination with other chemotherapeutic agents in colorectal, breast, pancreaticobiliary, gastric, renal cell and head and neck cancers.", "completion": "{\"entities\": [{\"text\": \"colorectal, breast, pancreaticobiliary, gastric, renal cell and head and neck cancers\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05209", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Agranulocytosis occurred 3 - 20 weeks after initiation of ticlopidine, so frequent examination of white cell count during treatment is recommended.", "completion": "{\"entities\": [{\"text\": \"Agranulocytosis\", \"type\": \"Disease\"}, {\"text\": \"ticlopidine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01036", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The symptoms exacerbated to a maximum in a month.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04962", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In a randomized, double - blind trial, 90 women were allocated to receive one of three treatments prior to induction of anaesthesia with propofol.", "completion": "{\"entities\": [{\"text\": \"propofol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04711", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Recurrent seizures were treated with diazepam and broad complex tachycardia was successfully treated with adenosine.", "completion": "{\"entities\": [{\"text\": \"seizures\", \"type\": \"Disease\"}, {\"text\": \"diazepam\", \"type\": \"Chemical\"}, {\"text\": \"tachycardia\", \"type\": \"Disease\"}, {\"text\": \"adenosine\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-reassigned-01670", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The chronic feeding of small amounts (0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02237", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 280 +/- 17 au ). Acute antinociceptive effects of the combination were partially prevented by 3.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01499", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: GNC92H2 was delivered 30 min before, concomitantly or 3 min after cocaine treatment.", "completion": "{\"entities\": [{\"text\": \"GNC92H2\", \"type\": \"Chemical\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05171", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The effect of treatment with gum Arabic on gentamicin nephrotoxicity in rats: a preliminary study.", "completion": "{\"entities\": [{\"text\": \"gum Arabic\", \"type\": \"Chemical\"}, {\"text\": \"gentamicin\", \"type\": \"Chemical\"}, {\"text\": \"nephrotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-05157", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Reserpine - and haloperidol - induced orofacial dyskinesia are putative animal models of tardive dyskinesia (TD) whose pathophysiology has been related to free radical generation and oxidative stress.", "completion": "{\"entities\": [{\"text\": \"Reserpine\", \"type\": \"Chemical\"}, {\"text\": \"haloperidol\", \"type\": \"Chemical\"}, {\"text\": \"orofacial dyskinesia\", \"type\": \"Disease\"}, {\"text\": \"tardive dyskinesia\", \"type\": \"Disease\"}, {\"text\": \"TD\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-02131", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These effects suggest that the protection from hemolysis by tocopherols is related to a decreased TAM incorporation in condensed membranes and the structural damage of the erythrocyte membrane is consequently avoided.", "completion": "{\"entities\": [{\"text\": \"hemolysis\", \"type\": \"Disease\"}, {\"text\": \"tocopherols\", \"type\": \"Chemical\"}, {\"text\": \"TAM\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02904", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We report a case of ranitidine - induced acute interstitial nephritis", "completion": "{\"entities\": [{\"text\": \"ranitidine\", \"type\": \"Chemical\"}, {\"text\": \"interstitial nephritis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00120", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It was concluded that labetalol offers advantages over nitroprusside", "completion": "{\"entities\": [{\"text\": \"labetalol\", \"type\": \"Chemical\"}, {\"text\": \"nitroprusside\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00699", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Acute peripheral neuropathy caused by a disulfiram overdose is very rare and there is no report of it leading to vocal fold palsy.", "completion": "{\"entities\": [{\"text\": \"peripheral neuropathy\", \"type\": \"Disease\"}, {\"text\": \"disulfiram\", \"type\": \"Chemical\"}, {\"text\": \"overdose\", \"type\": \"Disease\"}, {\"text\": \"vocal fold palsy\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03813", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Prolonged cholestasis after troleandomycin - induced acute hepatitis.", "completion": "{\"entities\": [{\"text\": \"cholestasis\", \"type\": \"Disease\"}, {\"text\": \"troleandomycin\", \"type\": \"Chemical\"}, {\"text\": \"hepatitis\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01460", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Women were randomly assigned to raloxifene 60 mg / d or 120 mg / d or placebo.", "completion": "{\"entities\": [{\"text\": \"raloxifene\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02670", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thymus weight was used as a marker of glucocorticoid activity, and serum urate to assess XO inhibition.", "completion": "{\"entities\": [{\"text\": \"urate\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01346", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: Cholinergic convulsant sensitivity was examined in alcohol - na ve Withdrawal Seizure - Prone (WSP) and - Resistant (WSR) mice.", "completion": "{\"entities\": [{\"text\": \"alcohol\", \"type\": \"Chemical\"}, {\"text\": \"Seizure\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02095", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Despite therapy with ursodeoxycholic acid, prednisone, and then tacrolimus, her cholestatic disease was unrelenting, with cirrhosis shown by biopsy 6 months after presentation.", "completion": "{\"entities\": [{\"text\": \"ursodeoxycholic acid\", \"type\": \"Chemical\"}, {\"text\": \"prednisone\", \"type\": \"Chemical\"}, {\"text\": \"tacrolimus\", \"type\": \"Chemical\"}, {\"text\": \"cholestatic disease\", \"type\": \"Disease\"}, {\"text\": \"cirrhosis\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-04590", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The effects of intracoronary administration of methylergonovine were studied in 21 patients with variant angina and 22 patients with atypical chest pain and in others without angina pectoris (control group ). Methylergonovine was administered continuously at a rate of 10 micrograms / min up to 50 micrograms.", "completion": "{\"entities\": [{\"text\": \"methylergonovine\", \"type\": \"Chemical\"}, {\"text\": \"variant angina\", \"type\": \"Disease\"}, {\"text\": \"chest pain\", \"type\": \"Disease\"}, {\"text\": \"angina pectoris\", \"type\": \"Disease\"}, {\"text\": \"Methylergonovine\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-03054", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cellular mechanisms which account for disruption the blood - brain barrier during acute hypertension are not clear.", "completion": "{\"entities\": [{\"text\": \"hypertension\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01712", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: Following induction of anesthesia by fentanyl (0.", "completion": "{\"entities\": [{\"text\": \"fentanyl\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01216", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 001 ). CONCLUSIONS: This study demonstrates that chronic FK506 nephropathy consists primarily of arteriolopathy manifesting as insudative hyalinosis of the arteriolar wall, and suggests that mild - type chronic FK506 nephropathy", "completion": "{\"entities\": [{\"text\": \"FK506\", \"type\": \"Chemical\"}, {\"text\": \"nephropathy\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00365", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Concentrations of coniine and nicotine sulfate were 0.", "completion": "{\"entities\": [{\"text\": \"coniine\", \"type\": \"Chemical\"}, {\"text\": \"nicotine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02652", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Rats were trained to approach a shelf where they received food reinforcement.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01841", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 1 %), cerebral infarction (3.", "completion": "{\"entities\": [{\"text\": \"cerebral infarction\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05083", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The men were randomly assigned to bupropion SR (150 mg twice daily, 117) or placebo (twice daily, 117) for 12 weeks.", "completion": "{\"entities\": [{\"text\": \"bupropion\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-reassigned-03115", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 7 mg compared with 8.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02254", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This non - receptor mediated inhibition requires de novo synthesis for restoration of functional GABA catabolism.", "completion": "{\"entities\": [{\"text\": \"GABA\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00299", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Over a range of 1 - 150 days of DES treatment, pairs of control and DES - treated rats were sacrificed, and their pituitaries dissociated enzymatically into single - cell preparations.", "completion": "{\"entities\": [{\"text\": \"DES\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01955", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Sodium chloride solution (0.", "completion": "{\"entities\": [{\"text\": \"Sodium chloride\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03252", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 6% sevoflurane, and in 0.", "completion": "{\"entities\": [{\"text\": \"sevoflurane\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01966", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0, indicating net tubular secretion for cimetidine.", "completion": "{\"entities\": [{\"text\": \"cimetidine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03211", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Subsequently, acute cardiac arrest and fatal subarachnoid hemorrhage occurred.", "completion": "{\"entities\": [{\"text\": \"cardiac arrest\", \"type\": \"Disease\"}, {\"text\": \"subarachnoid hemorrhage\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00359", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The angioedema resolved after therapy with intravenous steroids and diphenhydramine", "completion": "{\"entities\": [{\"text\": \"angioedema\", \"type\": \"Disease\"}, {\"text\": \"steroids\", \"type\": \"Chemical\"}, {\"text\": \"diphenhydramine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04511", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 7 %) had white matter abnormalities, 1 (7.", "completion": "{\"entities\": [{\"text\": \"white matter abnormalities\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04936", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This observation should be tested in studies of prolonged ketamine", "completion": "{\"entities\": [{\"text\": \"ketamine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04201", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The observed positive impact of nifedipine on reducing the nephrotoxicity associated with tacrolimus in liver transplant recipients should be an important factor in selecting an agent to treat hypertension", "completion": "{\"entities\": [{\"text\": \"nifedipine\", \"type\": \"Chemical\"}, {\"text\": \"nephrotoxicity\", \"type\": \"Disease\"}, {\"text\": \"tacrolimus\", \"type\": \"Chemical\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-reassigned-01701", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Potentiation of bupivacaine arrhythmia", "completion": "{\"entities\": [{\"text\": \"bupivacaine\", \"type\": \"Chemical\"}, {\"text\": \"arrhythmia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03076", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Possible mechanisms that involve a verapamil - related increase in platelet and / or vascular alpha 2 - adrenoreceptor affinity for catecholamines", "completion": "{\"entities\": [{\"text\": \"verapamil\", \"type\": \"Chemical\"}, {\"text\": \"catecholamines\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03703", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The overall response rate is 72 %. Eleven responding patients had subsequent surgery / radiotherapy or radical radiotherapy.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01825", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Whether pentoxifylline inhibits dipyridamole - induced coronary hyperemia like other methylxanthines such as theophylline and should be stopped prior to dipyridamole - thallium - 201 imaging is unknown.", "completion": "{\"entities\": [{\"text\": \"pentoxifylline\", \"type\": \"Chemical\"}, {\"text\": \"dipyridamole\", \"type\": \"Chemical\"}, {\"text\": \"hyperemia\", \"type\": \"Disease\"}, {\"text\": \"methylxanthines\", \"type\": \"Chemical\"}, {\"text\": \"theophylline\", \"type\": \"Chemical\"}, {\"text\": \"thallium\", \"type\": \"Chemical\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-02793", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Lamivudine was well tolerated and was continued in all patients.", "completion": "{\"entities\": [{\"text\": \"Lamivudine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00067", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Visual toxicity was of retinal origin and was characterized by a tritan - type dyschromatopsy, sometimes associated with a loss of visual acuity and pigmentary retinal deposits.", "completion": "{\"entities\": [{\"text\": \"Visual toxicity\", \"type\": \"Disease\"}, {\"text\": \"dyschromatopsy\", \"type\": \"Disease\"}, {\"text\": \"a loss of visual acuity\", \"type\": \"Disease\"}, {\"text\": \"pigmentary retinal deposits\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04005", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: For a period of 2 weeks, CsA 15 mg / kg / day (given orally ), FK506 3.", "completion": "{\"entities\": [{\"text\": \"CsA\", \"type\": \"Chemical\"}, {\"text\": \"FK506\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03910", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Transient platypnea-orthodeoxia-like syndrome induced by propafenone overdose in a young woman with Ebstein's anomaly.", "completion": "{\"entities\": [{\"text\": \"platypnea-orthodeoxia-like syndrome\", \"type\": \"Disease\"}, {\"text\": \"propafenone\", \"type\": \"Chemical\"}, {\"text\": \"overdose\", \"type\": \"Disease\"}, {\"text\": \"Ebstein's anomaly\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01105", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We selected the 54 (30.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04584", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Groups of 5 - week old male Fischer - 344 rats were fed for 7 - 25 months semipurified choline - devoid or choline - supplemented diets, containing or not 0.", "completion": "{\"entities\": [{\"text\": \"choline\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02760", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The duration of apnea was 5 - 15 min compared with 3 - 5.", "completion": "{\"entities\": [{\"text\": \"apnea\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05140", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A study on the effect of the duration of subcutaneous heparin injection on bruising and pain.", "completion": "{\"entities\": [{\"text\": \"heparin\", \"type\": \"Chemical\"}, {\"text\": \"bruising\", \"type\": \"Disease\"}, {\"text\": \"pain\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-reassigned-04896", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 38) and ibuprofen 1.", "completion": "{\"entities\": [{\"text\": \"ibuprofen\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03776", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Interaction of cyclosporin A with antineoplastic agents.", "completion": "{\"entities\": [{\"text\": \"cyclosporin A\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00670", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The possibility of de novo glomerular pathology under SRL", "completion": "{\"entities\": [{\"text\": \"SRL\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02469", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5% of patients had high - grade proteinuria (> 1.", "completion": "{\"entities\": [{\"text\": \"proteinuria\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00579", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 mg) was administered.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02033", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Morphological features of encephalopathy after chronic administration of the antiepileptic drug valproate to rats.", "completion": "{\"entities\": [{\"text\": \"encephalopathy\", \"type\": \"Disease\"}, {\"text\": \"valproate\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03407", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Finally, we strongly recommend to prospectively and regularly perform audiologic assessment in sick preterm children as hearing loss", "completion": "{\"entities\": [{\"text\": \"hearing loss\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00394", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: EBFF did not change during PGE1 infusion whereas in the TMP group, EBF decreased significantly at 30 and 60 min after the start of TMP (preinfusion: 45.", "completion": "{\"entities\": [{\"text\": \"PGE1\", \"type\": \"Chemical\"}, {\"text\": \"TMP\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02856", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We report a case of severe hypertension with an occluded renal artery to a solitary kidney, who developed sudden deterioration of renal function following treatment with captopril.", "completion": "{\"entities\": [{\"text\": \"hypertension\", \"type\": \"Disease\"}, {\"text\": \"sudden deterioration of renal function\", \"type\": \"Disease\"}, {\"text\": \"captopril\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00815", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 8] years ), and 49 (70 %) of them were women.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02558", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After discontinuing the oral alendronate, the patient underwent six cycles of hemodialysis and four cycles of LDL apheresis.", "completion": "{\"entities\": [{\"text\": \"alendronate\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02853", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 79) indicating that both rating retrievals utilized similar memory traces.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03700", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: At the time of this writing, dose level 4 (260, 270, and 280 mg / m2) is being evaluated; three patients from this level are evaluable.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04517", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 %) showed lower than normal ADC value and showed incomplete resolution with cortical laminar necrosis.", "completion": "{\"entities\": [{\"text\": \"cortical laminar necrosis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01906", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Serial audiograms should be performed every six months in those without problems and more frequently in young patients with normal serum ferritin values and in those with auditory dysfunction", "completion": "{\"entities\": [{\"text\": \"auditory dysfunction\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01961", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In 35 patients (ages 20 to 86 yr) receiving cimetidine therapeutically two serum samples and all urine formed in the interim were collected for analysis of cimetidine by high - pressure liquid chromatography and for creatinine.", "completion": "{\"entities\": [{\"text\": \"cimetidine\", \"type\": \"Chemical\"}, {\"text\": \"creatinine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01391", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: PATIENTS AND METHODS: Forty - two patients with biopsy - proven prostatic adenocarcinoma [26 with stage C (T3N0M0) and 16 with stage D1 (T3N1M0 )] were included in this study.", "completion": "{\"entities\": [{\"text\": \"prostatic adenocarcinoma\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00665", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5) g / d before and 4.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02882", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The first case involved a 59 - year - old man who used Dormex, which contains hydrogen cyanamide, without protection after consuming a large amount of alcohol during a meal.", "completion": "{\"entities\": [{\"text\": \"Dormex\", \"type\": \"Chemical\"}, {\"text\": \"hydrogen cyanamide\", \"type\": \"Chemical\"}, {\"text\": \"alcohol\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-05182", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: of the patients had experienced visual hallucinations before this event.", "completion": "{\"entities\": [{\"text\": \"visual hallucinations\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05040", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 15 10 (- 3) mm2) compared with the hypertensive", "completion": "{\"entities\": [{\"text\": \"hypertensive\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02273", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Estradiol reduces seizure - induced hippocampal injury in ovariectomized female but not in male rats.", "completion": "{\"entities\": [{\"text\": \"Estradiol\", \"type\": \"Chemical\"}, {\"text\": \"seizure\", \"type\": \"Disease\"}, {\"text\": \"hippocampal injury\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02816", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The purpose of this study was to investigate the influence of calcium channel blockers on bupivacaine - induced acute toxicity.", "completion": "{\"entities\": [{\"text\": \"calcium\", \"type\": \"Chemical\"}, {\"text\": \"bupivacaine\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03417", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05 ). The severity of M.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04391", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We discuss herein the possible mechanisms and the significance of mToR blockade - induced proteinuria", "completion": "{\"entities\": [{\"text\": \"proteinuria\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04540", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5, and multiple modes of reduction in the exencephalic tissue at E18.", "completion": "{\"entities\": [{\"text\": \"exencephalic\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04354", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: There was no significant difference in the frequency of signs or symptoms between the two groups although neurotoxicity symptoms presented mostly with lower scores of severity in group G.", "completion": "{\"entities\": [{\"text\": \"neurotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02105", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The patients who had been exposed to appetite suppressants tended to be on average more severely ill, and to have a shorter median delay between onset of symptoms and diagnosis.", "completion": "{\"entities\": [{\"text\": \"appetite suppressants\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03760", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Alpha-lipoic acid prevents mitochondrial damage and neurotoxicity in experimental chemotherapy neuropathy.", "completion": "{\"entities\": [{\"text\": \"Alpha-lipoic acid\", \"type\": \"Chemical\"}, {\"text\": \"mitochondrial damage\", \"type\": \"Disease\"}, {\"text\": \"neurotoxicity\", \"type\": \"Disease\"}, {\"text\": \"neuropathy\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04466", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: In the literature, the most - frequent cause of hemolytic uremic syndrome in patients following renal transplantation is recurrence of the hemolytic uremic syndrome.", "completion": "{\"entities\": [{\"text\": \"hemolytic uremic syndrome\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01326", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the bolus group, 26.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02681", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Risperidone is an antipsychotic drug with high affinity at dopamine D2 and serotonin 5-HT2 receptors.", "completion": "{\"entities\": [{\"text\": \"Risperidone\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}, {\"text\": \"serotonin 5-HT2\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02270", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 4 - fold over that seen in control ICH animals and the bleeding 7.", "completion": "{\"entities\": [{\"text\": \"ICH\", \"type\": \"Disease\"}, {\"text\": \"bleeding\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-03132", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A small increase (1.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-05179", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Although visual hallucinations have not been reported as an adverse effect of this agent, we describe three patients who experienced complex visual hallucinations and altered mental status after zonisamide treatment was begun or its dosage increased.", "completion": "{\"entities\": [{\"text\": \"visual hallucinations\", \"type\": \"Disease\"}, {\"text\": \"zonisamide\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04807", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: p .) was able to prevent amnesia induced by scopolamine (1 mg kg - 1 i.", "completion": "{\"entities\": [{\"text\": \"amnesia\", \"type\": \"Disease\"}, {\"text\": \"scopolamine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03853", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It is concluded that when this electroencephalographic and behavioural picture is seen in drug intoxication, in the absence of significant hypoxaemia", "completion": "{\"entities\": [{\"text\": \"hypoxaemia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02725", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Rats were given a single dose of adriamycin and one month later divided into four groups matched for albuminuria, blood pressure, and plasma albumin concentration.", "completion": "{\"entities\": [{\"text\": \"adriamycin\", \"type\": \"Chemical\"}, {\"text\": \"albuminuria\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02485", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: SAR studies led to compound 14 with excellent potency (K (i )= 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02470", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 g / day ); this increased to 22.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00458", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The median age of those patients developing Grade 3 - 4 neutropenia was significantly higher than that of the remaining patients (75 years vs.", "completion": "{\"entities\": [{\"text\": \"neutropenia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02245", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CNS toxic effects of the antineoplastic agent ifosfamide (IFX) are frequent and include a variety of neurological symptoms that can limit drug use.", "completion": "{\"entities\": [{\"text\": \"ifosfamide\", \"type\": \"Chemical\"}, {\"text\": \"IFX\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00498", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Various reported side effects of fentanyl administration include chest wall rigidity, hypotension, respiratory depression, and bradycardia.", "completion": "{\"entities\": [{\"text\": \"fentanyl\", \"type\": \"Chemical\"}, {\"text\": \"chest wall rigidity\", \"type\": \"Disease\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}, {\"text\": \"respiratory depression\", \"type\": \"Disease\"}, {\"text\": \"bradycardia\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-00351", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The presence of REM sleep was shown not to be a determining factor either for secretory pulse amplitude and frequency, as, for both, mean nocturnal values were similar with and without prior clomipramine", "completion": "{\"entities\": [{\"text\": \"clomipramine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04639", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: One week later, the patient was again extubated and 3 days later was transferred to a peripheral ward.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02586", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Twenty - eight patients (24 %) developed increased proteinuria from baseline during their post - transplantation course.", "completion": "{\"entities\": [{\"text\": \"proteinuria\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00222", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Since nonsteroidal anti - inflammatory agents interfere with this compensatory mechanism and may cause acute renal failure", "completion": "{\"entities\": [{\"text\": \"acute renal failure\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00691", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Health, physical abilities and cognitive function were compared between BZD / RD users and non - users, and adjustments were made for confounding variables.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03471", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The effects of varying the extracellular concentrations of Na and Ca ([Na] o and [Ca] o) on both, the spontaneous beating and the negative chronotropic action of verapamil, were studied in the isolated rat atria.", "completion": "{\"entities\": [{\"text\": \"Na\", \"type\": \"Chemical\"}, {\"text\": \"Ca\", \"type\": \"Chemical\"}, {\"text\": \"verapamil\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04255", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This case illustrates that patients receiving ritodrine for preterm labor may risk interactions between the residual betamimetic effects of ritodrine and the effects of anesthetics during cesarean section.", "completion": "{\"entities\": [{\"text\": \"ritodrine\", \"type\": \"Chemical\"}, {\"text\": \"preterm labor\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04115", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Clinical characteristics, medications, and serum chemistries at baseline and follow - up time periods were compared.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02204", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: For the cytoprotection study, animals were orally gavaged 100 mg / Kg GSPE for 7 - 10 days followed by i.", "completion": "{\"entities\": [{\"text\": \"GSPE\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02162", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Therefore, in the present experiment, the effects of clonidine administration (0.", "completion": "{\"entities\": [{\"text\": \"clonidine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05135", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The results showed that rats treated with Morphine / Rg1 decreased escape latency and increased the time spent in platform quadrant and entering frequency.", "completion": "{\"entities\": [{\"text\": \"Morphine\", \"type\": \"Chemical\"}, {\"text\": \"Rg1\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00342", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Lipid peroxidation in homogenates was maximal at day 3 and declined rapidly to control levels by day 17.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03108", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: The sensitivity improved dramatically from 16% to 79 %, positive predictive value increased from 60% to 68% and negative predictive value from 54% to 78 %, and specificity decreased from 90% to 67 %. CONCLUSIONS: If ECG alone is used for specificity, the combination with dP / dtejc improved the sensitivity of the test and could be a cost - savings alternative to cardiac imaging or perfusion studies to detect myocardial ischemia", "completion": "{\"entities\": [{\"text\": \"myocardial ischemia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05031", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 2 +/- 9 mg / 24 hr in the hypertensive controls.", "completion": "{\"entities\": [{\"text\": \"hypertensive\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04623", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Case report: acute unintentional carbachol intoxication.", "completion": "{\"entities\": [{\"text\": \"carbachol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03150", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Paclitaxel, cisplatin, and gemcitabine combination chemotherapy within a multidisciplinary therapeutic approach in metastatic nonsmall cell lung carcinoma.", "completion": "{\"entities\": [{\"text\": \"Paclitaxel\", \"type\": \"Chemical\"}, {\"text\": \"cisplatin\", \"type\": \"Chemical\"}, {\"text\": \"gemcitabine\", \"type\": \"Chemical\"}, {\"text\": \"nonsmall cell lung carcinoma\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01612", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Further studies are needed in order to establish a potential negative effect of maternal smoking", "completion": "{\"entities\": [{\"text\": \"smoking\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00159", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Does paracetamol cause urothelial cancer or renal papillary necrosis ? The risk of developing renal papillary necrosis or cancer of the renal pelvis, ureter or bladder associated with consumption of either phenacetin or paracetamol was calculated from data acquired by questionnaire from 381 cases and 808 controls.", "completion": "{\"entities\": [{\"text\": \"paracetamol\", \"type\": \"Chemical\"}, {\"text\": \"urothelial cancer\", \"type\": \"Disease\"}, {\"text\": \"renal papillary necrosis\", \"type\": \"Disease\"}, {\"text\": \"cancer of the renal pelvis, ureter or bladder\", \"type\": \"Disease\"}, {\"text\": \"phenacetin\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-00687", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 8 years) were admitted.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02279", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 17beta-Estradiol reduced the argyrophilic neurons in the CA1 and CA3 - C sectors of ovariectomized rats.", "completion": "{\"entities\": [{\"text\": \"17beta-Estradiol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01406", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 1 g / dl (X +/- SE ), whereas the other patients had mild anemia with Hb mean value of 13.", "completion": "{\"entities\": [{\"text\": \"anemia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03900", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: p .) reduced locomotor time, distance traveled and average speed (P < 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00849", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: OBJECTIVE: The globus pallidus plays a critical role in movement regulation.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01057", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Toxic hepatitis induced by antithyroid drugs: four cases including one with cross - reactivity between carbimazole and benzylthiouracil.", "completion": "{\"entities\": [{\"text\": \"Toxic hepatitis\", \"type\": \"Disease\"}, {\"text\": \"carbimazole\", \"type\": \"Chemical\"}, {\"text\": \"benzylthiouracil\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02669", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Systolic blood pressures (SBP) and bodyweights were recorded each alternate day.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02210", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Additionally, histopathological alterations mirrored both serum chemistry changes and the pattern of DNA fragmentation.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01777", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The remaining seven patients had isolated beta 2 microglobulinuria.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02079", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The surgery and anaesthesia were uneventful, but 3 days after surgery, the patient reported an area of hypoaesthesia over L3 - L4 dermatomes of the leg which had been operated on (loss of pinprick sensation) without reduction in muscular strength.", "completion": "{\"entities\": [{\"text\": \"loss of pinprick sensation\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04776", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Peripheral neuropathy occurred in 12 patients and pancreatitis in six.", "completion": "{\"entities\": [{\"text\": \"Peripheral neuropathy\", \"type\": \"Disease\"}, {\"text\": \"pancreatitis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03814", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We report the case of a patient in whom troleandomycin - induced hepatitis was followed by prolonged anicteric cholestasis.", "completion": "{\"entities\": [{\"text\": \"troleandomycin\", \"type\": \"Chemical\"}, {\"text\": \"hepatitis\", \"type\": \"Disease\"}, {\"text\": \"cholestasis\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00298", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pituitary tumors were induced in F344 female rats by chronic treatment with diethylstilbestrol (DES, 8 - 10 mg) implanted subcutaneously in silastic capsules.", "completion": "{\"entities\": [{\"text\": \"Pituitary tumors\", \"type\": \"Disease\"}, {\"text\": \"diethylstilbestrol\", \"type\": \"Chemical\"}, {\"text\": \"DES\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04296", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We evaluated the potential of the major metabolite of cocaine, benzoylecgonine (BE ), to cause seizures.", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"benzoylecgonine\", \"type\": \"Chemical\"}, {\"text\": \"BE\", \"type\": \"Chemical\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02421", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A novel compound, maltolyl p-coumarate, attenuates cognitive deficits and shows neuroprotective effects in vitro and in vivo dementia models.", "completion": "{\"entities\": [{\"text\": \"maltolyl p-coumarate\", \"type\": \"Chemical\"}, {\"text\": \"cognitive deficits\", \"type\": \"Disease\"}, {\"text\": \"dementia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01108", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: All the patients were skin test negative to BPO; 49 of 51 (96 %) were also negative to MDM, and 44 of 46 (96 %) to PG.", "completion": "{\"entities\": [{\"text\": \"BPO\", \"type\": \"Chemical\"}, {\"text\": \"MDM\", \"type\": \"Disease\"}, {\"text\": \"PG\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02679", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This, together with our previous findings that allopurinol failed to prevent adrenocorticotrophic hormone induced hypertension, suggests that XO activity is not a major determinant of GC - HT", "completion": "{\"entities\": [{\"text\": \"allopurinol\", \"type\": \"Chemical\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}, {\"text\": \"HT\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03540", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Eighteen of the DOX rats died prematurely of general toxicity during the 9 - week period.", "completion": "{\"entities\": [{\"text\": \"DOX\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-04200", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The incidence of cardiac events with VNR was 1.", "completion": "{\"entities\": [{\"text\": \"VNR\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03731", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 1981 ). In this study, the severity of response to other seizure - inducing agents was tested in mice 1 and 24 h after intraperitoneal administration of 80 mg / kg gamma-HCH.", "completion": "{\"entities\": [{\"text\": \"seizure\", \"type\": \"Disease\"}, {\"text\": \"gamma-HCH\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00206", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Fibrous myopathy is a common, well - known side effect of repeated pentazocine injection.", "completion": "{\"entities\": [{\"text\": \"Fibrous myopathy\", \"type\": \"Disease\"}, {\"text\": \"pentazocine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04714", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: PURPOSE: We evaluated the safety of indocyanine green for use in fundus angiography.", "completion": "{\"entities\": [{\"text\": \"indocyanine green\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-reassigned-00469", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 7 years after the end of treatment.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04819", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In future, this form of therapy can offer a safe alternative in the treatment of cyclophosphamide - induced hemorrhagic cystitis", "completion": "{\"entities\": [{\"text\": \"cyclophosphamide\", \"type\": \"Chemical\"}, {\"text\": \"hemorrhagic cystitis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01066", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSION: Toxic hepatitis is a potential adverse effect of antithyroid drugs which warrants, as for haematological disturbances, a pre - therapeutic determination and a careful follow - up of relevant biological markers.", "completion": "{\"entities\": [{\"text\": \"Toxic hepatitis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04318", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A 17 - day - old infant on isoniazid therapy 13 mg / kg daily from birth because of maternal tuberculosis was admitted after 4 days of clonic fits.", "completion": "{\"entities\": [{\"text\": \"isoniazid\", \"type\": \"Chemical\"}, {\"text\": \"tuberculosis\", \"type\": \"Disease\"}, {\"text\": \"clonic fits\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00419", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Other symptoms of allergic reactions were not clinically detectable.", "completion": "{\"entities\": [{\"text\": \"allergic reactions\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04565", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Delirium, which may be induced by tricyclic drug therapy in the elderly, can be caused by tricyclics with low anticholinergic potency.", "completion": "{\"entities\": [{\"text\": \"Delirium\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01823", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Dipyridamole - thallium - 201 imaging is often performed in patients unable to exercise because of peripheral vascular disease.", "completion": "{\"entities\": [{\"text\": \"Dipyridamole\", \"type\": \"Chemical\"}, {\"text\": \"thallium\", \"type\": \"Chemical\"}, {\"text\": \"peripheral vascular disease\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03120", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In particular, the tendency of cocaine to produce chest pain ought to be in the mind of the emergency nurse when faced with a young victim of chest pain who is otherwise at low risk.", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"chest pain\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00675", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Generally, atropine reduced contractions, but in contrast to controls, it also reduced responses to low electrical field stimulation intensity (1 - 5 Hz) in inflamed preparations.", "completion": "{\"entities\": [{\"text\": \"atropine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05056", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The subcutaneous administration of 10 mg / kg of morphine - HC1 produced a marked increase in locomotor activity in mice.", "completion": "{\"entities\": [{\"text\": \"morphine\", \"type\": \"Chemical\"}, {\"text\": \"increase in locomotor activity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02594", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This study measured the objective and subjective neurocognitive effects of a single 10 - mg dose of immediate - release oxycodone in healthy, older (> 65 years ), and middle - aged (35 to 55 years) adults who were not suffering from chronic or significant daily pain.", "completion": "{\"entities\": [{\"text\": \"oxycodone\", \"type\": \"Chemical\"}, {\"text\": \"pain\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02067", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: INTERPRETATION: Repeated exposure of human beings to HCFCs 123 and 124 can result in serious liver injury in a large proportion of the exposed population.", "completion": "{\"entities\": [{\"text\": \"HCFCs 123 and 124\", \"type\": \"Chemical\"}, {\"text\": \"liver injury\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03376", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the present study, we investigated the changes occurring at the protein level in striatal samples obtained from the unilaterally 6-hydroxydopamine - lesion rat model of PD treated with saline, L-DOPA or bromocriptine using two - dimensional difference gel electrophoresis and mass spectrometry (MS ). Rats treated with L-DOPA were allocated to two groups based on the presence or absence of LID.", "completion": "{\"entities\": [{\"text\": \"6-hydroxydopamine\", \"type\": \"Chemical\"}, {\"text\": \"PD\", \"type\": \"Disease\"}, {\"text\": \"L-DOPA\", \"type\": \"Chemical\"}, {\"text\": \"bromocriptine\", \"type\": \"Chemical\"}, {\"text\": \"LID\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-03250", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: There was no significant difference in the convulsive threshold between sevoflurane and enflurane.", "completion": "{\"entities\": [{\"text\": \"convulsive\", \"type\": \"Disease\"}, {\"text\": \"sevoflurane\", \"type\": \"Chemical\"}, {\"text\": \"enflurane\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01603", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The objective of this study was to determine the effects of maternal smoking on transient evoked otoacoustic emissions (TEOAEs) of healthy neonates.", "completion": "{\"entities\": [{\"text\": \"smoking\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03448", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Patients with SNHL presented with relatively lower serum ferritin levels than those with normal hearing, however, no statistically significant difference was observed.", "completion": "{\"entities\": [{\"text\": \"SNHL\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05058", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In contrast, both methscopolamine and neostigmine, which do not penetrate the blood - brain barrier, had no effect on the hyperactivity produced by morphine.", "completion": "{\"entities\": [{\"text\": \"methscopolamine\", \"type\": \"Chemical\"}, {\"text\": \"neostigmine\", \"type\": \"Chemical\"}, {\"text\": \"hyperactivity\", \"type\": \"Disease\"}, {\"text\": \"morphine\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00068", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Auditory toxicity was characterized by a mid - to high - frequency neurosensorial hearing loss and the lesion was of the cochlear type.", "completion": "{\"entities\": [{\"text\": \"Auditory toxicity\", \"type\": \"Disease\"}, {\"text\": \"neurosensorial hearing loss\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03288", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Infarct - avid radiopharmaceuticals are necessary for rapid and timely diagnosis of acute myocardial infarction.", "completion": "{\"entities\": [{\"text\": \"Infarct\", \"type\": \"Disease\"}, {\"text\": \"myocardial infarction\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04474", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Urinary bladder cancer in Wegener's granulomatosis: risks and relation to cyclophosphamide.", "completion": "{\"entities\": [{\"text\": \"Urinary bladder cancer\", \"type\": \"Disease\"}, {\"text\": \"Wegener's granulomatosis\", \"type\": \"Disease\"}, {\"text\": \"cyclophosphamide\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04019", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We tested the sulfated polysaccharide fucoidan, which has been reported to reduce inflammatory brain damage, in a rat model of intracerebral hemorrhage induced by injection of bacterial collagenase into the caudate nucleus.", "completion": "{\"entities\": [{\"text\": \"fucoidan\", \"type\": \"Chemical\"}, {\"text\": \"brain damage\", \"type\": \"Disease\"}, {\"text\": \"intracerebral hemorrhage\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03841", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The physician should also determine the proper use of any adjunctive medications; such combined therapy has become the standard approach to treatment.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02189", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Patients who are switched from cyclosporine to tacrolimus or vice versa should be closely monitored for the signs and symptoms of recurrent TMA", "completion": "{\"entities\": [{\"text\": \"cyclosporine\", \"type\": \"Chemical\"}, {\"text\": \"tacrolimus\", \"type\": \"Chemical\"}, {\"text\": \"TMA\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02790", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Two of these normalized and the others increased later.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02638", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Possible effects of ACE inhibition were tested.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04878", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 6 %, respectively ). Stratification of patients by sex, age, extent of concurrent smoking, extent of product use, and severity of adverse events revealed no clinically significant differences between the lozenge and gum.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02508", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Improvement and eventually full recovery only occurred after TAC was completely discontinued and successfully replaced by everolimus", "completion": "{\"entities\": [{\"text\": \"TAC\", \"type\": \"Chemical\"}, {\"text\": \"everolimus\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02251", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the patient described, the presence of asterixis during infusion of ifosfamide, normal laboratory findings and imaging studies and the resolution of symptoms following the discontinuation of the drug suggest that negative myoclonus is associated with the use of IFX", "completion": "{\"entities\": [{\"text\": \"asterixis\", \"type\": \"Disease\"}, {\"text\": \"ifosfamide\", \"type\": \"Chemical\"}, {\"text\": \"myoclonus\", \"type\": \"Disease\"}, {\"text\": \"IFX\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00908", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Irreversible damage to the medullary interstitium in experimental analgesic nephropathy in F344 rats.", "completion": "{\"entities\": [{\"text\": \"nephropathy\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04979", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0001 ). Recovery room discharge times were similar: C (75.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04760", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The patient developed weakness, lethargy, and shortness of breath 2 days after starting therapy with omeprazole.", "completion": "{\"entities\": [{\"text\": \"lethargy\", \"type\": \"Disease\"}, {\"text\": \"shortness of breath\", \"type\": \"Disease\"}, {\"text\": \"omeprazole\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-05016", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Electrophysiologic and hemodynamic effects of flestolol are similar to those of other beta blockers.", "completion": "{\"entities\": [{\"text\": \"flestolol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01872", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the five rats that developed somatic rigidity, ICP and CVP increased significantly above baseline (delta ICP 7.", "completion": "{\"entities\": [{\"text\": \"somatic rigidity\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02147", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Effects of long - term pretreatment with isoproterenol on bromocriptine - induced tachycardia in conscious rats.", "completion": "{\"entities\": [{\"text\": \"isoproterenol\", \"type\": \"Chemical\"}, {\"text\": \"bromocriptine\", \"type\": \"Chemical\"}, {\"text\": \"tachycardia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03011", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Bile duct hamartoma occurring in association with long - term treatment with danazol.", "completion": "{\"entities\": [{\"text\": \"Bile duct hamartoma\", \"type\": \"Disease\"}, {\"text\": \"danazol\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04822", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The results have shown that the degradation product p-choloroaniline is not a significant factor in chlorhexidine-digluconate associated erosive cystitis.", "completion": "{\"entities\": [{\"text\": \"p-choloroaniline\", \"type\": \"Chemical\"}, {\"text\": \"chlorhexidine-digluconate\", \"type\": \"Chemical\"}, {\"text\": \"cystitis\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00564", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In experimental nephrotic syndrome, urinary sodium excretion is decreased during the early phase of the disease.", "completion": "{\"entities\": [{\"text\": \"nephrotic syndrome\", \"type\": \"Disease\"}, {\"text\": \"sodium\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03350", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Neuroprotective action of MPEP, a selective mGluR5 antagonist, in methamphetamine - induced dopaminergic neurotoxicity is associated with a decrease in dopamine outflow and inhibition of hyperthermia in rats.", "completion": "{\"entities\": [{\"text\": \"MPEP\", \"type\": \"Chemical\"}, {\"text\": \"methamphetamine\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}, {\"text\": \"neurotoxicity\", \"type\": \"Disease\"}, {\"text\": \"hyperthermia\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-01492", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After cessation of the treatment, pseudolithiasis resolved spontaneously within a short period.", "completion": "{\"entities\": [{\"text\": \"pseudolithiasis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03142", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: VNB was administered weekly as a 25 - mg / m2 short intravenous (i.", "completion": "{\"entities\": [{\"text\": \"VNB\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03730", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Gamma-hexachlorocyclohexane (gamma-HCH ), the active ingredient of the insecticide lindane, has been shown to decrease seizure threshold to pentylenetrazol (PTZ) 3 h after exposure to gamma-HCH and conversely increase threshold to PTZ - induced seizures 24 h after exposure to gamma-HCH (Vohland et al.", "completion": "{\"entities\": [{\"text\": \"Gamma-hexachlorocyclohexane\", \"type\": \"Chemical\"}, {\"text\": \"gamma-HCH\", \"type\": \"Chemical\"}, {\"text\": \"lindane\", \"type\": \"Chemical\"}, {\"text\": \"seizure\", \"type\": \"Disease\"}, {\"text\": \"PTZ\", \"type\": \"Chemical\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-00956", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Diclofenac sodium (Voltarol, Geigy Pharmaceuticals) is a non - steroidal anti - inflammatory derivative of phenylacetic acid.", "completion": "{\"entities\": [{\"text\": \"Diclofenac sodium\", \"type\": \"Chemical\"}, {\"text\": \"Voltarol\", \"type\": \"Chemical\"}, {\"text\": \"phenylacetic acid\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00518", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Subjects supplied information on oral-contraceptive use and major cardiovascular risk factors.", "completion": "{\"entities\": [{\"text\": \"oral-contraceptive\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04606", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Dobutamine infusion at 10 micrograms / kg per min was discontinued after six studies secondary to a 50% incidence rate of adverse symptoms.", "completion": "{\"entities\": [{\"text\": \"Dobutamine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05133", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Male rats were subcutaneously injected with morphine (10 mg / kg) twice a day at 12 hour intervals for 10 days, and Rg1 (30 mg / kg) was intraperitoneally injected 2 hours after the second injection of morphine once a day for 10 days.", "completion": "{\"entities\": [{\"text\": \"morphine\", \"type\": \"Chemical\"}, {\"text\": \"Rg1\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03062", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The results obtained indicate that with all three carcinogens, administration of 5-AzC during repair synthesis increased the incidence of initiated hepatocytes, for example 10 - 20 foci / cm2 in 5-AzC and carcinogen - treated rats compared with 3 - 5 foci / cm2 in rats treated with carcinogen only.", "completion": "{\"entities\": [{\"text\": \"5-AzC\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00515", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We investigated this association, according to the type of progestagen included in third - generation (i.", "completion": "{\"entities\": [{\"text\": \"progestagen\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01628", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The patient recovered with intensive medical support.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-reassigned-01085", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We conclude that amlodipine can cause dysguesia.", "completion": "{\"entities\": [{\"text\": \"amlodipine\", \"type\": \"Chemical\"}, {\"text\": \"dysguesia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04948", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Most of the other low testosterone levels seemed to result from nonorganic hypothalamic dysfunction because of normal serum luteinizing hormone and prolactin and to have only a small role in erectile dysfunction (definite improvement in only 16 of 44 [36 %] after androgen therapy, normal morning or nocturnal erections in 30% and definite vasculogenic contributions in 42 %). Determining testosterone only in cases of low sexual desire or abnormal physical examination would have missed 40% of the cases with low testosterone, including 37% of those subsequently improved by androgen therapy.", "completion": "{\"entities\": [{\"text\": \"testosterone\", \"type\": \"Chemical\"}, {\"text\": \"hypothalamic dysfunction\", \"type\": \"Disease\"}, {\"text\": \"erectile dysfunction\", \"type\": \"Disease\"}, {\"text\": \"low sexual desire\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04726", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: PURPOSE: The influence of an irreversible inhibitor of constitutive NO synthase (L - NOArg; 1.", "completion": "{\"entities\": [{\"text\": \"NO\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02034", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A transmission electron microscopic study of capillaries in the cerebellar cortex.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00540", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Male Wistar rats were implanted bilaterally with cannulae into the accumbens shell or core, and then were locally injected with GR 55562 (an antagonist of 5 - HT1B receptors) or CP 93129 (an agonist of 5 - HT1B receptors ). Given alone to any accumbal subregion, GR 55562 (0.", "completion": "{\"entities\": [{\"text\": \"GR 55562\", \"type\": \"Chemical\"}, {\"text\": \"CP 93129\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01996", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Treatment was from weeks 0 to 8 and was then tapered from weeks 8 to 16.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02046", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The proliferation of astrocytes (Bergmann' s in particular) and occasionally of oligodendrocytes was found.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01732", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Clomipramine exposure in immature rats produced significant behavioral and biochemical changes that include enhanced anxiety (elevated plus maze and marble burying ), behavioral inflexibility (perseveration in the spontaneous alternation task and impaired reversal learning ), working memory impairment (e.", "completion": "{\"entities\": [{\"text\": \"Clomipramine\", \"type\": \"Chemical\"}, {\"text\": \"anxiety\", \"type\": \"Disease\"}, {\"text\": \"behavioral inflexibility\", \"type\": \"Disease\"}, {\"text\": \"memory impairment\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00637", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Upon additional retrospective analysis, it was noted that bumetanide is a loop diuretic that may cause significant hypocalcemia.", "completion": "{\"entities\": [{\"text\": \"bumetanide\", \"type\": \"Chemical\"}, {\"text\": \"loop diuretic\", \"type\": \"Chemical\"}, {\"text\": \"hypocalcemia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02767", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The purpose of the present study was to examine the safety and efficacy of ketamine for sedation in the treatment of children' s fractures in the emergency department.", "completion": "{\"entities\": [{\"text\": \"ketamine\", \"type\": \"Chemical\"}, {\"text\": \"fractures\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00379", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 67% of the time, while coniine - treated chicks were only moving 8.", "completion": "{\"entities\": [{\"text\": \"coniine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04338", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Despite similar external diameters among CaCl(2) - treated, non - CaCl(2) - treated and NaCl - treated segments, aneurymal alteration (n = 6, 50 %), media degeneration with regional disruption, fragmentation of elastic fiber, and increased collagen deposition (n = 12, 100 %) were demonstrated in CaCl(2) - treated segments.", "completion": "{\"entities\": [{\"text\": \"CaCl(2)\", \"type\": \"Chemical\"}, {\"text\": \"NaCl\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00339", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Kidney cortices from each animal were used to prepare homogenates.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01542", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CLINICAL FEATURES: A 50 - year - old woman with low back and right leg pain was scheduled for epidural steroid injection.", "completion": "{\"entities\": [{\"text\": \"low back and right leg pain\", \"type\": \"Disease\"}, {\"text\": \"steroid\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04420", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: E2 did, however, significantly suppress CD36 protein levels as measured by fluorescent immunocytochemistry.", "completion": "{\"entities\": [{\"text\": \"E2\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02178", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The differential effects of ketamine and lidocaine on static and dynamic hyperalgesia suggest that the two types of hyperalgesia", "completion": "{\"entities\": [{\"text\": \"ketamine\", \"type\": \"Chemical\"}, {\"text\": \"lidocaine\", \"type\": \"Chemical\"}, {\"text\": \"hyperalgesia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00028", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Rats with lithium - induced nephropathy were subjected to high protein (HP) feeding, uninephrectomy (NX) or a combination of these, in an attempt to induce glomerular hyperfiltration and further progression of renal failure.", "completion": "{\"entities\": [{\"text\": \"lithium\", \"type\": \"Chemical\"}, {\"text\": \"nephropathy\", \"type\": \"Disease\"}, {\"text\": \"renal failure\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00958", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The patient described developed chronic active hepatitis after six months therapy with diclofenac sodium", "completion": "{\"entities\": [{\"text\": \"chronic active hepatitis\", \"type\": \"Disease\"}, {\"text\": \"diclofenac sodium\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04477", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Through linkage with the Swedish Cancer Register, all subjects in this cohort diagnosed with bladder cancer were identified.", "completion": "{\"entities\": [{\"text\": \"Cancer\", \"type\": \"Disease\"}, {\"text\": \"bladder cancer\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01560", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Aortic atherosclerosis was diagnosed by radiographic detection of calcified deposits in the abdominal aorta, which have been shown to reflect intima atherosclerosis.", "completion": "{\"entities\": [{\"text\": \"atherosclerosis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00631", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Past medical history was remarkable for hypertension, hyperlipidemia, and depression.", "completion": "{\"entities\": [{\"text\": \"hypertension\", \"type\": \"Disease\"}, {\"text\": \"hyperlipidemia\", \"type\": \"Disease\"}, {\"text\": \"depression\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-reassigned-05160", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Azathioprine - induced suicidal erythrocyte death.", "completion": "{\"entities\": [{\"text\": \"Azathioprine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03411", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: S .) were correlated with serum concentrations and renal and hepatic function in 36 patients, 30 patients had no M.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00218", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Indomethacin - induced renal insufficiency: recurrence on rechallenge.", "completion": "{\"entities\": [{\"text\": \"Indomethacin\", \"type\": \"Chemical\"}, {\"text\": \"renal insufficiency\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04684", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: One patient had thrombotic thrombocytopenic purpura, three the hemolytic-uremic syndrome, and one an apparent forme fruste of one of these disorders.", "completion": "{\"entities\": [{\"text\": \"thrombotic thrombocytopenic purpura\", \"type\": \"Disease\"}, {\"text\": \"hemolytic-uremic syndrome\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05005", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 or 25 mg / kg caffeine was reduced from 50 to 5% by acetaminophen.", "completion": "{\"entities\": [{\"text\": \"caffeine\", \"type\": \"Chemical\"}, {\"text\": \"acetaminophen\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04959", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Prolactin should be determined only in cases of low sexual desire, gynecomastia and / or testosterone", "completion": "{\"entities\": [{\"text\": \"low sexual desire\", \"type\": \"Disease\"}, {\"text\": \"gynecomastia\", \"type\": \"Disease\"}, {\"text\": \"testosterone\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01301", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Infusion regimens were designed that rapidly achieved and maintained target - free concentrations of these drugs in plasma and data on the relationship between free concentration and changes in MAPD were obtained for these compounds.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02575", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, treatment is often limited by adverse effects.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-05098", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: better, among men who received bupropion than placebo, at 15.", "completion": "{\"entities\": [{\"text\": \"bupropion\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01451", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pretreatment of TCR, at a dose of 0.", "completion": "{\"entities\": [{\"text\": \"TCR\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00149", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Within 8 hours after initiation of therapy the patient died with a clinical picture resembling massive pulmonary obstruction due to choriocarcinomic tissue plugs, probably originating from the uterus.", "completion": "{\"entities\": [{\"text\": \"pulmonary obstruction\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02811", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 8 %) due to hypoxia caused by MZ use.", "completion": "{\"entities\": [{\"text\": \"hypoxia\", \"type\": \"Disease\"}, {\"text\": \"MZ\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01143", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 002 ). At the same time, the number of heparan sulphate anionic sites and the total anionic site surface (number of anionic sites x mean anionic site surface) in the lamina rara externa of the glomerular basement membrane was reduced by 19 %(p < 0.", "completion": "{\"entities\": [{\"text\": \"heparan sulphate\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01031", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: There was a fulminant clinical course from start of symptoms until death.", "completion": "{\"entities\": [{\"text\": \"death\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05081", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: OBJECTIVE: To determine the safety and efficacy of adjunctive bupropion sustained - release (SR) on male sexual dysfunction (SD) induced by a selective serotonin reuptake inhibitor (SSRI ), as SD is a common side - effect of SSRIs and the most effective treatments have yet to be determined.", "completion": "{\"entities\": [{\"text\": \"bupropion\", \"type\": \"Chemical\"}, {\"text\": \"sexual dysfunction\", \"type\": \"Disease\"}, {\"text\": \"SD\", \"type\": \"Disease\"}, {\"text\": \"selective serotonin reuptake inhibitor\", \"type\": \"Chemical\"}, {\"text\": \"SSRI\", \"type\": \"Chemical\"}, {\"text\": \"SSRIs\", \"type\": \"Chemical\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-04704", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the initial 6 months since it' s introduction, 12 overdose cases have been reported to The National Poisons Information Centre.", "completion": "{\"entities\": [{\"text\": \"overdose\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00448", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: Forty - nine patients with advanced NSCLC were included, 38 of whom were age >/= 70 years and 11 were age < 70 years but who had some contraindication to receiving cisplatin.", "completion": "{\"entities\": [{\"text\": \"NSCLC\", \"type\": \"Disease\"}, {\"text\": \"cisplatin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03141", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thirty patients without prior chemotherapy and 16 pretreated with cisplatin - based chemotherapy were assessable for toxicity and response.", "completion": "{\"entities\": [{\"text\": \"cisplatin\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04495", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Forearm [3H]-L-arginine extraction was calculated after infusion of [3H]-L-arginine into the brachial artery at a rate of 100 nCi / min for 80 minutes.", "completion": "{\"entities\": [{\"text\": \"[3H]-L-arginine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02932", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 %) in the rhesus monkey.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03138", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: European Organization for Research and Treatment of Cancer Gastrointestinal Treat Cancer Cooperative Group.", "completion": "{\"entities\": [{\"text\": \"Cancer\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03560", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Calcineurin - inhibitor induced pain syndrome (CIPS ): a severe disabling complication after organ transplantation.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"CIPS\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03018", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The association of granulomas and eosinophilia favor an immunoallergic mechanism.", "completion": "{\"entities\": [{\"text\": \"granulomas\", \"type\": \"Disease\"}, {\"text\": \"eosinophilia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03610", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Locomotor activity was measured again for 30 min at the beginning of days 1 and 21 of sugar access.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04740", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In high doses, its nonhematological dose - limiting toxicity is cardiomyopathy.", "completion": "{\"entities\": [{\"text\": \"toxicity\", \"type\": \"Disease\"}, {\"text\": \"cardiomyopathy\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00429", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Adverse effects of antipsychotics often lead to noncompliance.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00248", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Vitamin D3 toxicity in dairy cows.", "completion": "{\"entities\": [{\"text\": \"Vitamin D3\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02848", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Subjects were able to reliably discriminate pain magnitude and duration across capsaicin doses (both p < 0.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"capsaicin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05030", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 8 +/- 2 progressively to 163 +/- 55 compared with 19.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00539", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The present study was designed to examine the effect of 5 - HT1B receptor ligands microinjected into the subregions of the nucleus accumbens (the shell and the core) on the locomotor hyperactivity induced by cocaine in rats.", "completion": "{\"entities\": [{\"text\": \"locomotor hyperactivity\", \"type\": \"Disease\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02266", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The blood amounts and hematoma volumes were significantly correlated, and the hematoma induced by 0.", "completion": "{\"entities\": [{\"text\": \"hematoma\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03450", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Following intervention, 7 out of 21 affected patients recovered, 10 remained stable and 4 demonstrated aggravation.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-reassigned-04981", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 mm Hg with placebo.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02762", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Severe distress was noted in the recovery phase in two patients.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04902", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These data suggest distinct differences in the propensity to develop LIDs in monkeys with different rates of symptom progression or symptom durations prior to levodopa and demonstrate the value of these models for further studying the pathophysiology of LIDs", "completion": "{\"entities\": [{\"text\": \"LIDs\", \"type\": \"Disease\"}, {\"text\": \"levodopa\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01375", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 58 ]. Using as the reference group women who were not using oral contraception, had no recent pregnancy or menopausal symptoms, the case - control analysis gave an adjusted odds ratio (OR (adj )) of 7.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03830", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Minor elevations of creatine kinase levels are reported in about 5% of patients.", "completion": "{\"entities\": [{\"text\": \"creatine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04930", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Significant increases in drowsiness were reported in patients treated with ketamine in both groups and were more marked with ketamine 0.", "completion": "{\"entities\": [{\"text\": \"ketamine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01120", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Habitual use of acetaminophen as a risk factor for chronic renal failure: a comparison with phenacetin.", "completion": "{\"entities\": [{\"text\": \"acetaminophen\", \"type\": \"Chemical\"}, {\"text\": \"chronic renal failure\", \"type\": \"Disease\"}, {\"text\": \"phenacetin\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-05020", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It is concluded that flestolol is a potent, well - tolerated, ultra - short - acting beta - adrenergic blocking agent.", "completion": "{\"entities\": [{\"text\": \"flestolol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03689", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: One patient died, having presented in hepatic failure, and another, who had been taking methyldopa for 7 years, showed slower clinical and biochemical resolution over a period of several months.", "completion": "{\"entities\": [{\"text\": \"hepatic failure\", \"type\": \"Disease\"}, {\"text\": \"methyldopa\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00480", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These observations indicate that although the gamma-carboxyglutamate residues of matrix Gla protein are apparently required for its function as a calcification inhibitor, they are not required for its accumulation at calcification", "completion": "{\"entities\": [{\"text\": \"gamma-carboxyglutamate\", \"type\": \"Chemical\"}, {\"text\": \"calcification\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01868", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Intracranial pressure increases during alfentanil - induced rigidity.", "completion": "{\"entities\": [{\"text\": \"alfentanil\", \"type\": \"Chemical\"}, {\"text\": \"rigidity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03049", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In four patients, the arrhythmia was rapidly diagnosed and treated with disappearance of further episodes of the arrhythmia.", "completion": "{\"entities\": [{\"text\": \"arrhythmia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00042", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Because of the need for the development of new treatments for Crohn's disease, a pilot study was undertaken to estimate the pharmacodynamics and tolerability of fusidic acid treatment in chronic active, therapy - resistant patients.", "completion": "{\"entities\": [{\"text\": \"Crohn's disease\", \"type\": \"Disease\"}, {\"text\": \"fusidic acid\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04689", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A combination of 5 d of nelarabine (AraG) with 5 d of etoposide (VP) and cyclophosphamide (CPM) and prophylactic intrathecal chemotherapy was used as salvage therapy in seven children with refractory or relapsed T-cell leukaemia or lymphoma.", "completion": "{\"entities\": [{\"text\": \"nelarabine\", \"type\": \"Chemical\"}, {\"text\": \"AraG\", \"type\": \"Chemical\"}, {\"text\": \"etoposide\", \"type\": \"Chemical\"}, {\"text\": \"VP\", \"type\": \"Chemical\"}, {\"text\": \"cyclophosphamide\", \"type\": \"Chemical\"}, {\"text\": \"CPM\", \"type\": \"Chemical\"}, {\"text\": \"T-cell leukaemia or lymphoma\", \"type\": \"Disease\"}]}", "n_entities": 7}
{"ref": "bc5cdr-train-02400", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 39 ), whereas rates of SCr increases > or = 25% were 9.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02368", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This imply an incidence of 1.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01053", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: During the SNP infusion the control animals demonstrated a progressive increase in blood pressure to 61 torr, whereas the saralasin - treated animals showed no change.", "completion": "{\"entities\": [{\"text\": \"SNP\", \"type\": \"Chemical\"}, {\"text\": \"increase in blood pressure\", \"type\": \"Disease\"}, {\"text\": \"saralasin\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02198", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In this patient, renal artery stenosis combined with heart failure and diuretic therapy certainly resulted in a strong activation of the renin - angiotensin system (RAS ). Under such conditions, angiotensin II receptor blockade by losartan probably induced a critical fall in glomerular filtration pressure.", "completion": "{\"entities\": [{\"text\": \"renal artery stenosis\", \"type\": \"Disease\"}, {\"text\": \"heart failure\", \"type\": \"Disease\"}, {\"text\": \"angiotensin\", \"type\": \"Chemical\"}, {\"text\": \"angiotensin II\", \"type\": \"Chemical\"}, {\"text\": \"losartan\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-01643", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: While the mechanisms underlying cocaine' s rewarding effects have been studied extensively, less attention has been paid to the unpleasant behavioral states induced by cocaine, such as anxiety.", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"anxiety\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04816", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We then used hyperbaric oxygen at an absolute pressure of 2 atm, 5 days a week for 8 consecutive weeks.", "completion": "{\"entities\": [{\"text\": \"oxygen\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04238", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In 24 of these patients chemical cystitis was severe enough for them to drop out of the study.", "completion": "{\"entities\": [{\"text\": \"cystitis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01698", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Schizophrenia has been initially associated with dysfunction in dopamine neurotransmission.", "completion": "{\"entities\": [{\"text\": \"Schizophrenia\", \"type\": \"Disease\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05109", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 003 ). In linear regression analyses the CGI - SF score was not affected significantly by the duration of SD, type of SSRI used and age.", "completion": "{\"entities\": [{\"text\": \"SD\", \"type\": \"Disease\"}, {\"text\": \"SSRI\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01021", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Reduction in the dosage of amiodarone resulted in the disappearance of the sinoatrial block and the persistence of asymptomatic sinus bradycardia", "completion": "{\"entities\": [{\"text\": \"amiodarone\", \"type\": \"Chemical\"}, {\"text\": \"sinoatrial block\", \"type\": \"Disease\"}, {\"text\": \"sinus bradycardia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02885", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The second case occurred in a 55 - year - old farmer following cutaneous contact with Dormex.", "completion": "{\"entities\": [{\"text\": \"Dormex\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01486", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It is well known that ceftriaxone leads to pseudolithiasis in some patients.", "completion": "{\"entities\": [{\"text\": \"ceftriaxone\", \"type\": \"Chemical\"}, {\"text\": \"pseudolithiasis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01758", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: of fat - free dry weight, respectively) in the three treatment groups, being significantly decreased only in the last two.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03926", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Forty - four patients were enrolled in the study of which 7 (16 %) were ineligible.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00745", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The aim of this study was to delineate brain structures that are involved in NIN generation.", "completion": "{\"entities\": [{\"text\": \"NIN\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00283", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These results are similar to those previously found in healthy subjects.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02512", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, the incidence and severity of these abnormalities vary from study to study and their course after drug withdrawal has not been systematically assessed.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04910", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSION: Pericarditis may be the initial manifestation of drug - induced vasculitis attributable to propylthio- uracil", "completion": "{\"entities\": [{\"text\": \"Pericarditis\", \"type\": \"Disease\"}, {\"text\": \"vasculitis\", \"type\": \"Disease\"}, {\"text\": \"propylthio- uracil\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04312", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This prolonged depletion of dopamine in the striatum was antagonized by dizocilpine (MK-801, a non - competitive antagonist of NMDA receptors) or by LY274614 (a competitive antagonist of NMDA receptors ). The protective effect of LY274614 was dose - dependent, being maximum at 10 - 40 mgkg (i.", "completion": "{\"entities\": [{\"text\": \"dopamine\", \"type\": \"Chemical\"}, {\"text\": \"dizocilpine\", \"type\": \"Chemical\"}, {\"text\": \"MK-801\", \"type\": \"Chemical\"}, {\"text\": \"NMDA\", \"type\": \"Chemical\"}, {\"text\": \"LY274614\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-00535", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5) for those with a mutation CONCLUSIONS: The risk of myocardial infarction was increased among women who used second - generation oral contraceptives.", "completion": "{\"entities\": [{\"text\": \"myocardial infarction\", \"type\": \"Disease\"}, {\"text\": \"oral contraceptives\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02059", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Epidemic of liver disease caused by hydrochlorofluorocarbons used as ozone - sparing substitutes of chlorofluorocarbons.", "completion": "{\"entities\": [{\"text\": \"liver disease\", \"type\": \"Disease\"}, {\"text\": \"hydrochlorofluorocarbons\", \"type\": \"Chemical\"}, {\"text\": \"chlorofluorocarbons\", \"type\": \"Chemical\"}, {\"text\": \"ozone\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02755", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The aim of the study was to assess the clinical significance of genetic variants in butyrylcholinesterase gene (BCHE) in patients with a suspected prolonged duration of action of succinylcholine after ECT.", "completion": "{\"entities\": [{\"text\": \"succinylcholine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01969", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 9 microgram / ml 6 hr after a dose) in a group of 13 patients without liver or kidney disease who had cimetidine levels above 1.", "completion": "{\"entities\": [{\"text\": \"liver or kidney disease\", \"type\": \"Disease\"}, {\"text\": \"cimetidine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01639", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The interictal electroencephalogram (EEG) showed a generalized slowing to 5 per second theta rhythms with bilateral generalized high - amplitude discharges.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04242", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In patients that were free of recurrence during the first year, 80% remained tumor - free during the 2 - to 3 - year follow - up period.", "completion": "{\"entities\": [{\"text\": \"tumor\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04657", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 001 ). Faster relief of headache was the most important reason for preference, cited by 67.", "completion": "{\"entities\": [{\"text\": \"headache\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01963", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The extrapolated 6 - hr serum concentration of cimetidine per unit dose, after intravenous cimetidine, increased with age of the patients.", "completion": "{\"entities\": [{\"text\": \"cimetidine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04522", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Sequential observations of exencephaly and subsequent morphological changes by mouse exo utero development system: analysis of the mechanism of transformation from exencephaly to anencephaly.", "completion": "{\"entities\": [{\"text\": \"exencephaly\", \"type\": \"Disease\"}, {\"text\": \"anencephaly\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04761", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Two weeks after the initiation of therapy, her hematocrit had decreased from 44.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03183", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Carmofur - induced organic mental disorders.", "completion": "{\"entities\": [{\"text\": \"Carmofur\", \"type\": \"Chemical\"}, {\"text\": \"organic mental disorders\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03185", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Symptoms such as euphoria, emotional lability and puerile attitude noted in the patient were diagnosed as organic personality syndrome according to the criteria defined in the DSM - III - R.", "completion": "{\"entities\": [{\"text\": \"organic personality syndrome\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01217", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Memory facilitation and stimulation of endogenous nerve growth factor synthesis by the acetylcholine releaser PG-9.", "completion": "{\"entities\": [{\"text\": \"acetylcholine\", \"type\": \"Chemical\"}, {\"text\": \"PG-9\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02831", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: The cardiovascular responses to standing and head - up tilt were studied repeatedly in PD patients receiving selegiline and as the drug was withdrawn.", "completion": "{\"entities\": [{\"text\": \"PD\", \"type\": \"Disease\"}, {\"text\": \"selegiline\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-01689", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Each concentration of progesterone (6.", "completion": "{\"entities\": [{\"text\": \"progesterone\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04239", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: No systemic side - effects were observed.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02280", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In males, estradiol increased the total damage score.", "completion": "{\"entities\": [{\"text\": \"estradiol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00628", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Severe citrate toxicity complicating volunteer apheresis platelet donation.", "completion": "{\"entities\": [{\"text\": \"citrate\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03446", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 2 %) presented with high frequency sensorineural hearing loss (SNHL ), either unilateral or bilateral.", "completion": "{\"entities\": [{\"text\": \"sensorineural hearing loss\", \"type\": \"Disease\"}, {\"text\": \"SNHL\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04445", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Latencies to stages were also significantly shorter for CSS10 and CSS18 mice.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04971", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 7) than in Group C (5.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03939", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Nephrotoxicity of combined cephalothin - gentamicin regimen.", "completion": "{\"entities\": [{\"text\": \"Nephrotoxicity\", \"type\": \"Disease\"}, {\"text\": \"cephalothin\", \"type\": \"Chemical\"}, {\"text\": \"gentamicin\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00509", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Findings were confirmed ultrastructurally.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02453", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In males, the non - competitive NMDA antagonist dextromethorphan enhanced the antihyperalgesic effect of low to moderate doses of morphine in a dose - and time - dependent manner.", "completion": "{\"entities\": [{\"text\": \"NMDA\", \"type\": \"Chemical\"}, {\"text\": \"dextromethorphan\", \"type\": \"Chemical\"}, {\"text\": \"morphine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01189", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The expression of arginine vasopressin (AVP) gene in the paraventricular (PVN) and supraoptic nuclei (SON) was investigated in rats with lithium (Li )- induced polyuria, using in situ hybridization histochemistry and radioimmunoassay.", "completion": "{\"entities\": [{\"text\": \"arginine vasopressin\", \"type\": \"Chemical\"}, {\"text\": \"AVP\", \"type\": \"Chemical\"}, {\"text\": \"lithium\", \"type\": \"Chemical\"}, {\"text\": \"Li\", \"type\": \"Chemical\"}, {\"text\": \"polyuria\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-00974", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Systolic pressure variation is greater during hemorrhage than during sodium nitroprusside - induced hypotension in ventilated dogs.", "completion": "{\"entities\": [{\"text\": \"hemorrhage\", \"type\": \"Disease\"}, {\"text\": \"sodium nitroprusside\", \"type\": \"Chemical\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03598", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: FINDINGS: FS containing tAMCA caused paroxysmal brain activity which was associated with distinct convulsive behaviours.", "completion": "{\"entities\": [{\"text\": \"tAMCA\", \"type\": \"Chemical\"}, {\"text\": \"convulsive\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01367", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This study shows that prenatal dexamethasone in rats results in a reduction in glomerular number, glomerulosclerosis, and hypertension when administered at specific points during gestation.", "completion": "{\"entities\": [{\"text\": \"dexamethasone\", \"type\": \"Chemical\"}, {\"text\": \"reduction in glomerular number\", \"type\": \"Disease\"}, {\"text\": \"glomerulosclerosis\", \"type\": \"Disease\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03533", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: Thirty - five Wistar rats were given 1.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01790", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The results indicate that acute nicotine injection induces a pronounced hyperactivity in rats habituated to the test environment.", "completion": "{\"entities\": [{\"text\": \"nicotine\", \"type\": \"Chemical\"}, {\"text\": \"hyperactivity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00210", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A patient with cryptogenic cirrhosis and disseminated sporotrichosis developed acute renal failure immediately following the administration of amphotericin B on four separate occasions.", "completion": "{\"entities\": [{\"text\": \"cirrhosis\", \"type\": \"Disease\"}, {\"text\": \"sporotrichosis\", \"type\": \"Disease\"}, {\"text\": \"acute renal failure\", \"type\": \"Disease\"}, {\"text\": \"amphotericin B\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04647", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The analysed carbachol concentration exceeded the supposed serum level resulting from a therapeutic dose by a factor of 130 to 260.", "completion": "{\"entities\": [{\"text\": \"carbachol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01372", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: The age - adjusted incidence rate ratio for CPA / EE versus conventional COCs was 2.", "completion": "{\"entities\": [{\"text\": \"CPA\", \"type\": \"Chemical\"}, {\"text\": \"EE\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03174", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Evaluation of adverse reactions of aponidine hydrochloride ophthalmic solution.", "completion": "{\"entities\": [{\"text\": \"aponidine hydrochloride\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00502", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: To determine mitochondrial events from HAART in vivo, 8 - week - old hemizygous transgenic AIDS mice (NL4 - 3Delta gag / pol; TG) and wild - type FVB / n littermates were treated with the HAART combination of zidovudine, lamivudine, and indinavir or vehicle control for 10 days or 35 days.", "completion": "{\"entities\": [{\"text\": \"AIDS\", \"type\": \"Disease\"}, {\"text\": \"zidovudine\", \"type\": \"Chemical\"}, {\"text\": \"lamivudine\", \"type\": \"Chemical\"}, {\"text\": \"indinavir\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01861", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Resting irCRF levels are suppressed only at the highest corticosterone infusion rate, which resulted in systemic corticosterone levels of 40 micrograms / dl.", "completion": "{\"entities\": [{\"text\": \"corticosterone\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00125", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the course of developing this model, a common vehicle, propylene glycol, by itself in high doses, was found to exhibit protective properties against induced seizures and inhibited weight gain.", "completion": "{\"entities\": [{\"text\": \"propylene glycol\", \"type\": \"Chemical\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}, {\"text\": \"weight gain\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02428", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Taking these in vitro and in vivo results together, our study suggests that maltolyl p-coumarate is a potentially effective candidate against Alzheimer's disease that is characterized by wide spread neuronal death and progressive decline of cognitive function", "completion": "{\"entities\": [{\"text\": \"maltolyl p-coumarate\", \"type\": \"Chemical\"}, {\"text\": \"Alzheimer's disease\", \"type\": \"Disease\"}, {\"text\": \"neuronal death\", \"type\": \"Disease\"}, {\"text\": \"decline of cognitive function\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04140", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: Patients who are more than 10 years post - OLTX have CRF and ESRD at a high rate.", "completion": "{\"entities\": [{\"text\": \"CRF\", \"type\": \"Disease\"}, {\"text\": \"ESRD\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00713", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: PATIENTS AND METHODS: Patients with more than 50% decrease in platelet count or thrombocytopenia (< 150 x 10 (9 )/ L) after exposure to heparin, who had a positive two - step antigen assay [optical density (OD )> 0.", "completion": "{\"entities\": [{\"text\": \"thrombocytopenia\", \"type\": \"Disease\"}, {\"text\": \"heparin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03858", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Patients were randomly allocated to either receive or not receive 1 1 fentanyl, while a third group received dexamethasone in addition to fentanyl.", "completion": "{\"entities\": [{\"text\": \"fentanyl\", \"type\": \"Chemical\"}, {\"text\": \"dexamethasone\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04127", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: At 13 years after OLTX, the incidence of severe renal dysfunction was 18.", "completion": "{\"entities\": [{\"text\": \"renal dysfunction\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04757", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It has been shown to be extremely effective in the treatment of peptic ulcer disease, reflux esophagitis, and the Zollinger-Ellison syndrome.", "completion": "{\"entities\": [{\"text\": \"peptic ulcer disease\", \"type\": \"Disease\"}, {\"text\": \"reflux esophagitis\", \"type\": \"Disease\"}, {\"text\": \"Zollinger-Ellison syndrome\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03706", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: No dose - limiting hematologic toxicity has been seen.", "completion": "{\"entities\": [{\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00051", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Biochemically, an increase in alkaline phosphatases was noted in 5 of 8 cases (63 %), and the greatest increases were seen in those who had elevated levels prior to treatment.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01898", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Audiograms from 15 patients remained abnormal and four patients required hearing aids because of permanent disability.", "completion": "{\"entities\": [{\"text\": \"permanent disability\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-reassigned-04848", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 7) with olanzapine and 23.", "completion": "{\"entities\": [{\"text\": \"olanzapine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01867", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These results indicate that noradrenergic neurons have an important role in the manifestation of catalepsy induced by THC, whereas dopaminergic neurons are important in catalepsy induced by haloperidol", "completion": "{\"entities\": [{\"text\": \"catalepsy\", \"type\": \"Disease\"}, {\"text\": \"THC\", \"type\": \"Chemical\"}, {\"text\": \"haloperidol\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03921", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: A Phase II study of the combination of cisplatin plus amifostine was conducted in patients with progressive metastatic breast carcinoma who had received one, but not more than one, chemotherapy regimen for metastatic disease.", "completion": "{\"entities\": [{\"text\": \"cisplatin\", \"type\": \"Chemical\"}, {\"text\": \"amifostine\", \"type\": \"Chemical\"}, {\"text\": \"breast carcinoma\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04263", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Electron microscopy disclosed many secretory granules, slightly distorted rough endoplasmic reticulum, and partially dilated Golgi cisternae in the prolactinoma cells.", "completion": "{\"entities\": [{\"text\": \"prolactinoma\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04454", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We did not find abnormalities in the expression and distribution of an mtDNA - encoded subunit of CCO (CCO - I) or a relative decrease in CCO - I when compared with nuclear - encoded subunits (CCO - IV and SDH - fp ). No abnormality in CCO activity was observed through histochemistry.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04504", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We conclude that cortisol - induced increases in blood pressure are not associated with abnormalities in the l-arginine", "completion": "{\"entities\": [{\"text\": \"cortisol\", \"type\": \"Chemical\"}, {\"text\": \"increases in blood pressure\", \"type\": \"Disease\"}, {\"text\": \"l-arginine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03578", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In 80 cases insufficient information was available for adequate comment and in 29 a relationship to the administration of clioquinol could be excluded.", "completion": "{\"entities\": [{\"text\": \"clioquinol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02633", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Permeability, ultrastructural changes, and distribution of novel proteins in the glomerular barrier in early puromycin aminonucleoside nephrosis.", "completion": "{\"entities\": [{\"text\": \"puromycin aminonucleoside\", \"type\": \"Chemical\"}, {\"text\": \"nephrosis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-00468", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 001) identified as late as 7.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-reassigned-04221", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 ), compared to 38.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-reassigned-03634", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: There were no statistically significant differences in EPSs between groups.", "completion": "{\"entities\": [{\"text\": \"EPSs\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00775", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Confusion, a rather serious adverse drug reaction with valproic acid: a review of the French Pharmacovigilance database.", "completion": "{\"entities\": [{\"text\": \"Confusion\", \"type\": \"Disease\"}, {\"text\": \"valproic acid\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02826", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Selegiline - induced postural hypotension in Parkinson's disease: a longitudinal study on the effects of drug withdrawal.", "completion": "{\"entities\": [{\"text\": \"Selegiline\", \"type\": \"Chemical\"}, {\"text\": \"postural hypotension\", \"type\": \"Disease\"}, {\"text\": \"Parkinson's disease\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03408", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pharmacokinetic and clinical studies in patients with cimetidine - associated mental confusion.", "completion": "{\"entities\": [{\"text\": \"cimetidine\", \"type\": \"Chemical\"}, {\"text\": \"confusion\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00253", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 mg / 100 ml ). of the cows treated with vitamin D3 showed signs of milk fever during the peripartal period; however, 22% of the control cows developed clinical signs of milk fever during this period.", "completion": "{\"entities\": [{\"text\": \"vitamin D3\", \"type\": \"Chemical\"}, {\"text\": \"milk fever\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02709", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CLINICAL SIGNIFICANCE: This clinical case showing oral manifestations of meth mouth was presented to help dental practitioners recognize and manage patients who may be abusing methamphetamines", "completion": "{\"entities\": [{\"text\": \"meth mouth\", \"type\": \"Disease\"}, {\"text\": \"methamphetamines\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03135", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: Pharmacokinetic differences in statins are an important consideration for assessing the risk of potential drug interactions.", "completion": "{\"entities\": [{\"text\": \"statins\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01122", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: As a result of these and other studies, phenacetin has now been withdrawn from the market in most countries.", "completion": "{\"entities\": [{\"text\": \"phenacetin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-reassigned-05781", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Transfusion reaction workup was negative.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04025", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Acute white matter edema and eventual neuronal loss in the striatum adjacent to the hematoma did not differ between the two groups.", "completion": "{\"entities\": [{\"text\": \"white matter edema\", \"type\": \"Disease\"}, {\"text\": \"neuronal loss\", \"type\": \"Disease\"}, {\"text\": \"hematoma\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01344", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: The septo - hippocampal cholinergic pathway has been implicated in epileptogenesis, and genetic factors influence the response to cholinergic agents, but limited data are available on cholinergic involvement in alcohol withdrawal severity.", "completion": "{\"entities\": [{\"text\": \"alcohol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03267", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Dexamethasone (Dex )- induced hypertension is characterized by endothelial dysfunction associated with nitric oxide (NO) deficiency and increased superoxide (O2-) production.", "completion": "{\"entities\": [{\"text\": \"Dex\", \"type\": \"Chemical\"}, {\"text\": \"Dexamethasone\", \"type\": \"Chemical\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}, {\"text\": \"nitric oxide\", \"type\": \"Chemical\"}, {\"text\": \"NO\", \"type\": \"Chemical\"}, {\"text\": \"superoxide\", \"type\": \"Chemical\"}, {\"text\": \"O2-\", \"type\": \"Chemical\"}]}", "n_entities": 7}
{"ref": "bc5cdr-train-04392", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Hypothalamic prolactin receptor messenger ribonucleic acid levels, prolactin signaling, and hyperprolactinemic inhibition of pulsatile luteinizing hormone secretion are dependent on estradiol.", "completion": "{\"entities\": [{\"text\": \"ribonucleic acid\", \"type\": \"Chemical\"}, {\"text\": \"hyperprolactinemic\", \"type\": \"Disease\"}, {\"text\": \"estradiol\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02325", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Focal glutamate photostimulation of the granule cell layer at sites distant from the recording pipette resulted in population responses of 1 - 30 s duration in slices from SE survivors but not other groups.", "completion": "{\"entities\": [{\"text\": \"glutamate\", \"type\": \"Chemical\"}, {\"text\": \"SE\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02908", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A patient is reported who developed progressive cardiomyopathy two and one - half years after receiving 580 mg / m2 which apparently represents late, late cardiotoxicity", "completion": "{\"entities\": [{\"text\": \"cardiomyopathy\", \"type\": \"Disease\"}, {\"text\": \"cardiotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00591", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Formation of coronary aneurysm is a rare complication of stenting with bare metal stents, but based on experimental studies drug - eluting stents may induce toxic effects on the vessel wall with incomplete stent apposition, aneurysm formation and with the potential of stent thrombosis or vessel rupture.", "completion": "{\"entities\": [{\"text\": \"coronary aneurysm\", \"type\": \"Disease\"}, {\"text\": \"aneurysm\", \"type\": \"Disease\"}, {\"text\": \"thrombosis\", \"type\": \"Disease\"}, {\"text\": \"vessel rupture\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03565", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Magnetic resonance imaging demonstrated bone marrow oedema in the painful bones.", "completion": "{\"entities\": [{\"text\": \"bone marrow oedema\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00309", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: All these effects of DES were more pronounced among previously ovariectomized animals.", "completion": "{\"entities\": [{\"text\": \"DES\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00569", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The kinetics of urinary sodium excretion and the appearance of proteinuria were comparable with those reported previously.", "completion": "{\"entities\": [{\"text\": \"sodium\", \"type\": \"Chemical\"}, {\"text\": \"proteinuria\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02315", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These responses were blocked by systemic pre - administration of hexamethonium chloride (20 mg / kg ). The evoked increases in dural blood flow were also abolished by topical pre - administration of atropine (1 mm) and [Lys1, Pro2, 5, Arg3, 4, Tyr6 ]- VIP (0.", "completion": "{\"entities\": [{\"text\": \"hexamethonium chloride\", \"type\": \"Chemical\"}, {\"text\": \"increases in dural blood flow\", \"type\": \"Disease\"}, {\"text\": \"atropine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01381", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 18) for use of conventional COCs.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04110", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We therefore sought to determine the prevalence and clinical associations of hyperkalemia and renal insufficiency in heart failure patients treated with spironolactone.", "completion": "{\"entities\": [{\"text\": \"hyperkalemia\", \"type\": \"Disease\"}, {\"text\": \"renal insufficiency\", \"type\": \"Disease\"}, {\"text\": \"heart failure\", \"type\": \"Disease\"}, {\"text\": \"spironolactone\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00506", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Molecularly, ANF mRNA increased 250% and SERCA2 mRNA decreased 57 %. Biochemically, LA was elevated (8.", "completion": "{\"entities\": [{\"text\": \"LA\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02438", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The latter group was further sub - divided into 13 occult HBV (HBsAg - negative) and 7 overt HBV (HBsAg - positive) patients.", "completion": "{\"entities\": [{\"text\": \"HBsAg\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02449", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In acute pain models, N-methyl-D-aspartate (NMDA) antagonists enhance the antinociceptive effects of morphine to a greater extent in males than females.", "completion": "{\"entities\": [{\"text\": \"acute pain\", \"type\": \"Disease\"}, {\"text\": \"N-methyl-D-aspartate\", \"type\": \"Chemical\"}, {\"text\": \"NMDA\", \"type\": \"Chemical\"}, {\"text\": \"morphine\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01896", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Twenty - two patients in the affected group had abnormal audiograms with deficits mostly in the high frequency range of 4,000 to 8,000 Hz and in the hearing threshold levels of 30 to 100 decibels.", "completion": "{\"entities\": [{\"text\": \"abnormal audiograms with deficits mostly in the high frequency range of 4,000 to 8,000 Hz\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01609", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Mean TEOAEs responses of highly exposed newborns were also significantly lower in comparison to our control group.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00497", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Fentanyl, an opioid analgesic, is frequently used in the neonatal intensive care unit setting for these very purposes.", "completion": "{\"entities\": [{\"text\": \"Fentanyl\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03867", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSION: As fentanyl exacerbated postoperative nausea and vomiting without an improvement in postoperative pain and also had adverse cardiorespiratory effects, it appears to be an unnecessary and possibly detrimental supplement to sevoflurane", "completion": "{\"entities\": [{\"text\": \"fentanyl\", \"type\": \"Chemical\"}, {\"text\": \"postoperative nausea and vomiting\", \"type\": \"Disease\"}, {\"text\": \"postoperative pain\", \"type\": \"Disease\"}, {\"text\": \"sevoflurane\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01673", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Grade 3 - 4 adverse effects included myelosuppression, fatigue, somnolence / depressed mood, neuropathy and dyspnea.", "completion": "{\"entities\": [{\"text\": \"myelosuppression\", \"type\": \"Disease\"}, {\"text\": \"fatigue\", \"type\": \"Disease\"}, {\"text\": \"somnolence\", \"type\": \"Disease\"}, {\"text\": \"depressed mood\", \"type\": \"Disease\"}, {\"text\": \"neuropathy\", \"type\": \"Disease\"}, {\"text\": \"dyspnea\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-01694", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The acetylcholine receptor antibody titer and response to acetylcholinesterase inhibitors were negative, and the results of thyroid function tests were normal.", "completion": "{\"entities\": [{\"text\": \"acetylcholine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00072", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Myasthenia gravis presenting as weakness after magnesium administration.", "completion": "{\"entities\": [{\"text\": \"Myasthenia gravis\", \"type\": \"Disease\"}, {\"text\": \"magnesium\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05066", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Mechanisms of FK 506 - induced hypertension in the rat .- Tacrolimus (FK 506) is a powerful, widely used immunosuppressant.", "completion": "{\"entities\": [{\"text\": \"FK 506\", \"type\": \"Chemical\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}, {\"text\": \"Tacrolimus\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02812", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Transient hypotension (SAP < 90mmHg) occurred in 1 patient (0.", "completion": "{\"entities\": [{\"text\": \"hypotension\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04855", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In vehicle - treated rats, status epilepticus caused pronounced neuronal damage in the piriform cortex comprising both pyramidal cells and interneurons.", "completion": "{\"entities\": [{\"text\": \"status epilepticus\", \"type\": \"Disease\"}, {\"text\": \"neuronal damage\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03304", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: For the subsequent 6 - week double - blind crossover phase (phase B ), patients taking standard - or low - dose haloperidol were switched to placebo, and patients taking placebo were randomly assigned to standard - or low - dose haloperidol.", "completion": "{\"entities\": [{\"text\": \"haloperidol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02155", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 mg / kg ). Neither cardiac vagal nor sympathetic tone was altered by isoproterenol pretreatment.", "completion": "{\"entities\": [{\"text\": \"isoproterenol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03239", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: l (- 1) with lidocaine infusion (6 mg.", "completion": "{\"entities\": [{\"text\": \"lidocaine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00761", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This hemorrhagic ulcer and various ulcerogenic parameters were dose - dependently ameliorated by daily intragastric verapamil.", "completion": "{\"entities\": [{\"text\": \"hemorrhagic\", \"type\": \"Disease\"}, {\"text\": \"ulcer\", \"type\": \"Disease\"}, {\"text\": \"verapamil\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-05053", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The underlying mechanism causing the neuropathy", "completion": "{\"entities\": [{\"text\": \"neuropathy\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00380", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 95% of a 5 - min interval, and no movement was observed for nicotine sulfate treated chicks.", "completion": "{\"entities\": [{\"text\": \"nicotine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00441", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In addition, neither TET nor FAN showed any anticoagulation activities in the measurement of the activated partial thromboplastin time (APTT ), prothrombin time (PT) and thrombin time (TT) using human - citrated plasma.", "completion": "{\"entities\": [{\"text\": \"TET\", \"type\": \"Chemical\"}, {\"text\": \"FAN\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01815", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 90 to detect a slowing to 25% of the expected rate of progression of weakness at P less than 0.", "completion": "{\"entities\": [{\"text\": \"weakness\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02350", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Their ototoxicity is a serious health problem and, as their ototoxic mechanism involves the production of NO, we need to assess the use of NO inhibitors for the prevention of aminoglycoside - induced sensorineural hearing loss.", "completion": "{\"entities\": [{\"text\": \"ototoxic\", \"type\": \"Disease\"}, {\"text\": \"ototoxicity\", \"type\": \"Disease\"}, {\"text\": \"NO\", \"type\": \"Chemical\"}, {\"text\": \"aminoglycoside\", \"type\": \"Chemical\"}, {\"text\": \"sensorineural hearing loss\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-02892", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The aim of the present study was to find out whether TRI given repeatedly was able to induce adaptive changes in the dopaminergic and alpha1 - adrenergic systems, demonstrated by us previously for various antidepressants.", "completion": "{\"entities\": [{\"text\": \"TRI\", \"type\": \"Chemical\"}, {\"text\": \"antidepressants\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01690", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These findings indicate the synergistic protective effect of green tea and vitamin E during ISO induced myocardial infarction", "completion": "{\"entities\": [{\"text\": \"green tea\", \"type\": \"Chemical\"}, {\"text\": \"vitamin E\", \"type\": \"Chemical\"}, {\"text\": \"ISO\", \"type\": \"Chemical\"}, {\"text\": \"myocardial infarction\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03903", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: v .) could partially reverse such effects of THP (3.", "completion": "{\"entities\": [{\"text\": \"THP\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02629", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Treatment - related adverse events (AEs) occurred in 44% and 52 %, 57 %, and 41% of the asenapine at 5 and 10 mg BID, haloperidol, and placebo groups, respectively.", "completion": "{\"entities\": [{\"text\": \"asenapine\", \"type\": \"Chemical\"}, {\"text\": \"haloperidol\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02360", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We conclude that methylphenidate mediated vasculitis should be considered in patients with neurological symptoms and a history of methylphenidate therapy.", "completion": "{\"entities\": [{\"text\": \"methylphenidate\", \"type\": \"Chemical\"}, {\"text\": \"vasculitis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05069", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In addition, the effect of the specific endothelin type A receptor antagonist FR 139317 on FK 506 - induced hypertension in rats was studied.", "completion": "{\"entities\": [{\"text\": \"FR 139317\", \"type\": \"Chemical\"}, {\"text\": \"FK 506\", \"type\": \"Chemical\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04853", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The effect of PDTC on status epilepticus - associated cell loss in the hippocampus and piriform cortex was evaluated in the rat fractionated pilocarpine model.", "completion": "{\"entities\": [{\"text\": \"PDTC\", \"type\": \"Chemical\"}, {\"text\": \"status epilepticus\", \"type\": \"Disease\"}, {\"text\": \"pilocarpine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02106", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A policy of unrestricted prescription of appetite suppressants may lead to a high incidence of associated primary pulmonary hypertension.", "completion": "{\"entities\": [{\"text\": \"appetite suppressants\", \"type\": \"Chemical\"}, {\"text\": \"primary pulmonary hypertension\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02928", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 mg / kg; a single male also received WR242511 orally (PO) at 7.", "completion": "{\"entities\": [{\"text\": \"WR242511\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00266", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Migraine (20 %) was not an uncommon cause of cranial neuropathy although malignancies arising from the reticuloendothelial system or related structures of the head and neck were more frequent (26 %). In 26.", "completion": "{\"entities\": [{\"text\": \"Migraine\", \"type\": \"Disease\"}, {\"text\": \"cranial neuropathy\", \"type\": \"Disease\"}, {\"text\": \"malignancies\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04408", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Many patients, however, develop negative long - term side effects such as premature atherosclerosis.", "completion": "{\"entities\": [{\"text\": \"premature atherosclerosis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04407", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Individuals with HIV can now live long lives with drug therapy that often includes protease inhibitors such as ritonavir.", "completion": "{\"entities\": [{\"text\": \"ritonavir\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03963", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: His medical history was unremarkable, except for minor fractures of the fingers and foot.", "completion": "{\"entities\": [{\"text\": \"fractures\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01982", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Attenuation of the lithium - induced diabetes-insipidus-like syndrome by amiloride in rats.", "completion": "{\"entities\": [{\"text\": \"lithium\", \"type\": \"Chemical\"}, {\"text\": \"diabetes-insipidus-like syndrome\", \"type\": \"Disease\"}, {\"text\": \"amiloride\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01818", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Side effects attributable to mazindol included decreased appetite (36 %), dry mouth (10 %), behavioral change (22 %), and gastrointestinal symptoms (18 %); mazindol dosage was reduced in 43% of patients.", "completion": "{\"entities\": [{\"text\": \"mazindol\", \"type\": \"Chemical\"}, {\"text\": \"decreased appetite\", \"type\": \"Disease\"}, {\"text\": \"dry mouth\", \"type\": \"Disease\"}, {\"text\": \"gastrointestinal symptoms\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03170", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Nonhematologic toxicities were mild.", "completion": "{\"entities\": [{\"text\": \"toxicities\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01019", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Amiodarone - induced sinoatrial block.", "completion": "{\"entities\": [{\"text\": \"Amiodarone\", \"type\": \"Chemical\"}, {\"text\": \"sinoatrial block\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00280", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Delayed free recall was also impaired but the two drugs did not differ.", "completion": "{\"entities\": [{\"text\": \"Delayed free recall was also impaired\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02180", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The development of thrombotic microangiopathy (TMA) associated with the use of cyclosporine has been well documented.", "completion": "{\"entities\": [{\"text\": \"thrombotic microangiopathy\", \"type\": \"Disease\"}, {\"text\": \"TMA\", \"type\": \"Disease\"}, {\"text\": \"cyclosporine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04204", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A 40 - year - old man with leukemia and no history of cardiac disease developed recurrent, brief episodes of apparent sinus arrest while receiving continuous - infusion cimetidine 50 mg / hour.", "completion": "{\"entities\": [{\"text\": \"leukemia\", \"type\": \"Disease\"}, {\"text\": \"cardiac disease\", \"type\": \"Disease\"}, {\"text\": \"sinus arrest\", \"type\": \"Disease\"}, {\"text\": \"cimetidine\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03626", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Anthracyclines are effective antineoplastic drugs, but they frequently cause dose - related cardiotoxicity.", "completion": "{\"entities\": [{\"text\": \"Anthracyclines\", \"type\": \"Chemical\"}, {\"text\": \"cardiotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04409", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We have previously demonstrated that ritonavir treatment increases atherosclerotic lesion formation in male mice to a greater extent than in female mice.", "completion": "{\"entities\": [{\"text\": \"ritonavir\", \"type\": \"Chemical\"}, {\"text\": \"atherosclerotic lesion\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00776", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: INTRODUCTION: Confusion is an adverse drug reaction frequently observed with valproic acid.", "completion": "{\"entities\": [{\"text\": \"Confusion\", \"type\": \"Disease\"}, {\"text\": \"valproic acid\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04521", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pulmonary hypertension developed after administration of a somatostatin analogue, octreotide, to enhance resolution of the fistula", "completion": "{\"entities\": [{\"text\": \"Pulmonary hypertension\", \"type\": \"Disease\"}, {\"text\": \"octreotide\", \"type\": \"Chemical\"}, {\"text\": \"fistula\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03636", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These preliminary results suggest that BNP may be useful as an early and sensitive indicator of anthracycline - induced cardiotoxicity", "completion": "{\"entities\": [{\"text\": \"anthracycline\", \"type\": \"Chemical\"}, {\"text\": \"cardiotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02134", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Additionally, since membrane leakage is a final stage of cytotoxicity, the disruption of the structural characteristics of biomembranes by TAM", "completion": "{\"entities\": [{\"text\": \"TAM\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02893", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: TRI was given to male Wistar rats and male Albino Swiss mice perorally twice daily for 14 days.", "completion": "{\"entities\": [{\"text\": \"TRI\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00104", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In patient 2, in addition to an increase in both deoxycorticosterone and 11-deoxycortisol levels, plasma aldosterone values were raised, with a concomitant suppression of renin levels.", "completion": "{\"entities\": [{\"text\": \"deoxycorticosterone\", \"type\": \"Chemical\"}, {\"text\": \"11-deoxycortisol\", \"type\": \"Chemical\"}, {\"text\": \"aldosterone\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01578", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Although these adverse effects occur in some patients, their occurrence could be minimised by knowledge of the molecular effects of sirolimus on the kidney, the use of sirolimus in appropriate patient populations, close monitoring of proteinuria and renal function, use of angiotensin - converting enzyme inhibitors or angiotensin II receptor blockers if proteinuria occurs and withdrawal if needed.", "completion": "{\"entities\": [{\"text\": \"sirolimus\", \"type\": \"Chemical\"}, {\"text\": \"proteinuria\", \"type\": \"Disease\"}, {\"text\": \"angiotensin\", \"type\": \"Chemical\"}, {\"text\": \"angiotensin II\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00133", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Mean arterial pressure (as a percentage of control +/- SEM) during randomized infusions of 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01709", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Phenylephrine but not ephedrine reduces frontal lobe oxygenation following anesthesia - induced hypotension.", "completion": "{\"entities\": [{\"text\": \"Phenylephrine\", \"type\": \"Chemical\"}, {\"text\": \"ephedrine\", \"type\": \"Chemical\"}, {\"text\": \"reduces frontal lobe oxygenation\", \"type\": \"Disease\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03933", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We present the case of a 28 - year - old man on chronic warfarin therapy who sustained a minor muscle tear and developed increasing pain and a flexure contracture of the right hip.", "completion": "{\"entities\": [{\"text\": \"warfarin\", \"type\": \"Chemical\"}, {\"text\": \"muscle tear\", \"type\": \"Disease\"}, {\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"contracture\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03965", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, when the patient was questioned about use of herbal products and supplements, the use of creatine monohydrate was revealed.", "completion": "{\"entities\": [{\"text\": \"creatine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03545", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Only five of the controls exhibited evidence of very slight perivascular fibrosis.", "completion": "{\"entities\": [{\"text\": \"fibrosis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00949", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Fluoxetine - induced akathisia: clinical and theoretical implications.", "completion": "{\"entities\": [{\"text\": \"Fluoxetine\", \"type\": \"Chemical\"}, {\"text\": \"akathisia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02841", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In order to address long - term pain memory, nine healthy male volunteers received intradermal injections of three doses of capsaicin (0.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"capsaicin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00457", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Three patients with severe neutropenia (6 %) died of sepsis.", "completion": "{\"entities\": [{\"text\": \"neutropenia\", \"type\": \"Disease\"}, {\"text\": \"sepsis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04781", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: Fourteen patients chronically infected with hepatitis C virus were treated by pegylated interferon alpha 2a and ribavirin.", "completion": "{\"entities\": [{\"text\": \"chronically infected with hepatitis C virus\", \"type\": \"Disease\"}, {\"text\": \"pegylated interferon alpha 2a\", \"type\": \"Chemical\"}, {\"text\": \"ribavirin\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00478", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Because Warfarin treatment had no effect on the elevation in serum calcium produced by vitamin D, the synergy between Warfarin and vitamin D is probably best explained by the hypothesis that Warfarin inhibits the activity of matrix Gla protein as a calcification inhibitor.", "completion": "{\"entities\": [{\"text\": \"Warfarin\", \"type\": \"Chemical\"}, {\"text\": \"calcium\", \"type\": \"Chemical\"}, {\"text\": \"vitamin D\", \"type\": \"Chemical\"}, {\"text\": \"calcification\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03125", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: A 72 - year - old white man with underlying human immunodeficiency virus, atrial fibrillation, coronary artery disease, and hyperlipidemia presented with generalized pain, fatigue, and dark orange urine for 3 days.", "completion": "{\"entities\": [{\"text\": \"human immunodeficiency virus\", \"type\": \"Disease\"}, {\"text\": \"atrial fibrillation\", \"type\": \"Disease\"}, {\"text\": \"coronary artery disease\", \"type\": \"Disease\"}, {\"text\": \"hyperlipidemia\", \"type\": \"Disease\"}, {\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"fatigue\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-04081", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The present study aimed to investigate the anticonvulsant activity as well as the effects on the level of hippocampal amino acid neurotransmitters (glutamate, aspartate, glycine and GABA) of N-(2-propylpentanoyl)urea (VPU) in comparison to its parent compound, valproic acid (VPA ). VPU was more potent than VPA, exhibiting the median effective dose (ED (50 )) of 49 mg / kg in protecting rats against pilocarpine - induced seizure whereas the corresponding value for VPA was 322 mg / kg.", "completion": "{\"entities\": [{\"text\": \"amino acid\", \"type\": \"Chemical\"}, {\"text\": \"glutamate\", \"type\": \"Chemical\"}, {\"text\": \"aspartate\", \"type\": \"Chemical\"}, {\"text\": \"glycine\", \"type\": \"Chemical\"}, {\"text\": \"GABA\", \"type\": \"Chemical\"}, {\"text\": \"N-(2-propylpentanoyl)urea\", \"type\": \"Chemical\"}, {\"text\": \"VPU\", \"type\": \"Chemical\"}, {\"text\": \"valproic acid\", \"type\": \"Chemical\"}, {\"text\": \"VPA\", \"type\": \"Chemical\"}, {\"text\": \"pilocarpine\", \"type\": \"Chemical\"}, {\"text\": \"seizure\", \"type\": \"Disease\"}]}", "n_entities": 11}
{"ref": "bc5cdr-train-02716", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Immunological activation has been proposed to play a role in methamphetamine - induced dopaminergic terminal damage.", "completion": "{\"entities\": [{\"text\": \"methamphetamine\", \"type\": \"Chemical\"}, {\"text\": \"dopaminergic terminal damage\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-03474", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Administration of nocistatin (1.", "completion": "{\"entities\": [{\"text\": \"nocistatin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01782", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the present study the role of habituation to the experimental environment on the stimulant effect of nicotine in rats was examined.", "completion": "{\"entities\": [{\"text\": \"nicotine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01150", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After drug administration, creatinine concentrations in the plasma and in the urine of the rats were determined, as well as creatinine clearance.", "completion": "{\"entities\": [{\"text\": \"creatinine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00605", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Administration of graded doses of U-II (1 - 10, 000 ng / mouse) provoked :(1) a dose - dependent reduction in the number of head dips in the hole - board test ;(2) a dose - dependent reduction in the number of entries in the white chamber in the black - and - white compartment test, and in the number of entries in the central platform and open arms in the plus - maze test; and (3) a dose - dependent increase in the duration of immobility in the forced - swimming test and tail suspension test.", "completion": "{\"entities\": [{\"text\": \"U-II\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01711", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We describe the effect of phenylephrine and ephedrine on frontal lobe oxygenation (S (c) O (2 )) following anesthesia - induced hypotension.", "completion": "{\"entities\": [{\"text\": \"phenylephrine\", \"type\": \"Chemical\"}, {\"text\": \"ephedrine\", \"type\": \"Chemical\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03895", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: p .). RAMH per se showed significant reduction in locomotor time, distance traveled and average speed but THP (15 mg / kg i.", "completion": "{\"entities\": [{\"text\": \"RAMH\", \"type\": \"Chemical\"}, {\"text\": \"THP\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00069", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Desferrioxamine withdrawal resulted in a complete recovery of visual function in 1 patient and partial recovery in 3, and a complete reversal of hearing loss in 3 patients and partial recovery in 3.", "completion": "{\"entities\": [{\"text\": \"Desferrioxamine\", \"type\": \"Chemical\"}, {\"text\": \"hearing loss\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01114", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Diagnosis of these patients can be achieved only if specific AX", "completion": "{\"entities\": [{\"text\": \"AX\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00059", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Sulpiride is a selective D2 - receptor antagonist with antipsychotic and antidepressant properties.", "completion": "{\"entities\": [{\"text\": \"Sulpiride\", \"type\": \"Chemical\"}, {\"text\": \"antidepressant\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01339", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Antithymocyte globulin in the treatment of D-penicillamine - induced aplastic anemia.", "completion": "{\"entities\": [{\"text\": \"Antithymocyte globulin\", \"type\": \"Chemical\"}, {\"text\": \"D-penicillamine\", \"type\": \"Chemical\"}, {\"text\": \"aplastic anemia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01218", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The effects of PG-9 (3alpha-tropyl 2-(p-bromophenyl)propionate ), the acetylcholine releaser, on memory processes and nerve growth factor (NGF) synthesis were evaluated.", "completion": "{\"entities\": [{\"text\": \"PG-9\", \"type\": \"Chemical\"}, {\"text\": \"3alpha-tropyl 2-(p-bromophenyl)propionate\", \"type\": \"Chemical\"}, {\"text\": \"acetylcholine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-reassigned-04483", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 56) for nonaspirin NSAIDs.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04490", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We investigate whether abnormalities in L-arginine uptake contribute to this deficiency.", "completion": "{\"entities\": [{\"text\": \"L-arginine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01533", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: p .). Daucus carota extract (200, 400 mg / kg, p.", "completion": "{\"entities\": [{\"text\": \"Daucus carota extract\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03512", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: There was also a higher incidence of tachyarrhythmias (P less than 0.", "completion": "{\"entities\": [{\"text\": \"tachyarrhythmias\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01677", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Priapism is the prolonged erection of the penis in the absence of sexual arousal.", "completion": "{\"entities\": [{\"text\": \"Priapism\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03638", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: OBJECTIVE: To estimate the association between antibacterial medications and selected birth defects.", "completion": "{\"entities\": [{\"text\": \"birth defects\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04604", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5, 5 and 10 micrograms / kg per min were administered.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04446", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CSS mapping suggests seizure susceptibility loci on mouse Chromosomes 10 and 18.", "completion": "{\"entities\": [{\"text\": \"seizure\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01900", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Auditory deterioration and improvement, demonstrated serially in individual patients receiving and not receiving deferoxamine, respectively, provided convincing evidence for a cause - and - effect relation between deferoxamine administration and ototoxicity.", "completion": "{\"entities\": [{\"text\": \"deferoxamine\", \"type\": \"Chemical\"}, {\"text\": \"ototoxicity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00901", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Mean peak forced expiratory volume in 1 second (FEV1) increases over baseline and the proportion of patients attaining at least a 15% increase in the FEV1 (responders) were 31% and 90 %, respectively, for ipratropium and 17% and 50 %, respectively, for theophylline.", "completion": "{\"entities\": [{\"text\": \"ipratropium\", \"type\": \"Chemical\"}, {\"text\": \"theophylline\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04513", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 1 %) had normal findings on initial MR images.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02171", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: infusion of ketamine (bolus 0.", "completion": "{\"entities\": [{\"text\": \"ketamine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05116", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The objectives were to assess the efficacy of lamivudine in reducing the incidence of HBV reactivation, and diminishing morbidity and mortality during CT.", "completion": "{\"entities\": [{\"text\": \"lamivudine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03781", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The hematologic effects of cefonicid and cefazedone in the dog: a potential model of cephalosporin hematotoxicity in man.", "completion": "{\"entities\": [{\"text\": \"cefonicid\", \"type\": \"Chemical\"}, {\"text\": \"cefazedone\", \"type\": \"Chemical\"}, {\"text\": \"cephalosporin\", \"type\": \"Chemical\"}, {\"text\": \"hematotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00352", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Angioedema following the intravenous administration of metoprolol.", "completion": "{\"entities\": [{\"text\": \"Angioedema\", \"type\": \"Disease\"}, {\"text\": \"metoprolol\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05145", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Heparin was injected over 10 seconds on the right abdominal site and 30 seconds on the left abdominal site.", "completion": "{\"entities\": [{\"text\": \"Heparin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00563", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Epithelial sodium channel (ENaC) subunit mRNA and protein expression in rats with puromycin aminonucleoside - induced nephrotic syndrome.", "completion": "{\"entities\": [{\"text\": \"sodium\", \"type\": \"Chemical\"}, {\"text\": \"puromycin aminonucleoside\", \"type\": \"Chemical\"}, {\"text\": \"nephrotic syndrome\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01298", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The potential of compounds to cause TDP was evaluated by monitoring their effects on MAPD in dog.", "completion": "{\"entities\": [{\"text\": \"TDP\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00538", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Effects of 5 - HT1B receptor ligands microinjected into the accumbal shell or core on the cocaine - induced locomotor hyperactivity in rats.", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"locomotor hyperactivity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02658", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Angiosarcoma of the liver associated with diethylstilbestrol.", "completion": "{\"entities\": [{\"text\": \"Angiosarcoma of the liver\", \"type\": \"Disease\"}, {\"text\": \"diethylstilbestrol\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04933", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 50 mg / kg of ketamine.", "completion": "{\"entities\": [{\"text\": \"ketamine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01073", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Severe hematologic toxicity (neutrophil count < 1000 / mm3 and / or hemoglobin < 8 g / dl) occurred in 4 patients assigned to group I and 7 assigned to group II.", "completion": "{\"entities\": [{\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01916", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In contrast, dosages of Mipafox (less than or equal to 5 mg / kg) which inhibited mean NTE activity in spinal cord less than or equal to 61% and brain less than or equal to 60% produced this degree of cord damage in only 9% of the animals.", "completion": "{\"entities\": [{\"text\": \"Mipafox\", \"type\": \"Chemical\"}, {\"text\": \"cord damage\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04734", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Moreover, L - NOArg and 7 - NI but not L - NIL intensify antihyperalgesic activity of HOE 140 or des-Arg10HOE 140 in toxic neuropathy.", "completion": "{\"entities\": [{\"text\": \"HOE 140\", \"type\": \"Chemical\"}, {\"text\": \"des-Arg10HOE 140\", \"type\": \"Chemical\"}, {\"text\": \"toxic neuropathy\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01588", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The mechanism of this myopathy is uncertain but may involve the induction by statins", "completion": "{\"entities\": [{\"text\": \"myopathy\", \"type\": \"Disease\"}, {\"text\": \"statins\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00438", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: p .) of TET and FAN in mice showed the inhibition of thrombosis by 55% and 35 %, respectively, while acetylsalicylic acid (ASA, 50 mg / kg, i.", "completion": "{\"entities\": [{\"text\": \"TET\", \"type\": \"Chemical\"}, {\"text\": \"FAN\", \"type\": \"Chemical\"}, {\"text\": \"thrombosis\", \"type\": \"Disease\"}, {\"text\": \"acetylsalicylic acid\", \"type\": \"Chemical\"}, {\"text\": \"ASA\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-00565", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The molecular mechanism (s) leading to salt retention has not been completely elucidated.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02311", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: An experimental model was developed in the rat to measure changes in lacrimation and intracranial blood flow following noxious chemical stimulation of facial mucosa.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04163", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, identification of a short - acting local anesthetic to substitute for lidocaine for brief surgical procedures remains an important goal.", "completion": "{\"entities\": [{\"text\": \"lidocaine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-reassigned-00345", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CIN developed in 25.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02911", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We studied 20 patients receiving long - term carbonic anhydrase inhibitor treatment for periodic paralysis and myotonia.", "completion": "{\"entities\": [{\"text\": \"paralysis\", \"type\": \"Disease\"}, {\"text\": \"myotonia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03879", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Experimental and clinical evidence points to a role of central histaminergic system in the pathogenesis of schizophrenia.", "completion": "{\"entities\": [{\"text\": \"schizophrenia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-reassigned-02596", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: All others received cyclosporine and prednisone.", "completion": "{\"entities\": [{\"text\": \"cyclosporine\", \"type\": \"Chemical\"}, {\"text\": \"prednisone\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-00136", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 7% of patients needed hospitalization.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01210", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Both the temporal relationship of events and the response to treatment suggest that a rapid systemic absorption of mepivacaine with adrenaline", "completion": "{\"entities\": [{\"text\": \"mepivacaine\", \"type\": \"Chemical\"}, {\"text\": \"adrenaline\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-04818", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 6 %) and risperidone (54.", "completion": "{\"entities\": [{\"text\": \"risperidone\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00669", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Therefore, conversion should be considered for patients who have not developed advanced CAN and proteinuria.", "completion": "{\"entities\": [{\"text\": \"CAN\", \"type\": \"Disease\"}, {\"text\": \"proteinuria\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00907", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These results show that ipratropium is a more potent bronchodilator than oral theophylline in patients with chronic airflow obstruction", "completion": "{\"entities\": [{\"text\": \"ipratropium\", \"type\": \"Chemical\"}, {\"text\": \"theophylline\", \"type\": \"Chemical\"}, {\"text\": \"chronic airflow obstruction\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03116", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: regular consumption of alcohol, liver failure is possible when therapeutic doses are ingested.", "completion": "{\"entities\": [{\"text\": \"alcohol\", \"type\": \"Chemical\"}, {\"text\": \"liver failure\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03124", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: OBJECTIVE: To report a case of a severe interaction between simvastatin, amiodarone, and atazanavir resulting in rhabdomyolysis and acute renal failure.", "completion": "{\"entities\": [{\"text\": \"simvastatin\", \"type\": \"Chemical\"}, {\"text\": \"amiodarone\", \"type\": \"Chemical\"}, {\"text\": \"atazanavir\", \"type\": \"Chemical\"}, {\"text\": \"rhabdomyolysis\", \"type\": \"Disease\"}, {\"text\": \"acute renal failure\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-01646", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The Dbh -/- mice had normal baseline performance in the EPM but were completely resistant to the anxiogenic effects of cocaine.", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04075", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These rats also showed declines in left ventricular systolic pressure, maximum and minimum rate of developed left ventricular pressure, and elevation of left ventricular end - diastolic pressure and ST - segment.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00314", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Factors affecting triamterene nephrolithiasis", "completion": "{\"entities\": [{\"text\": \"triamterene\", \"type\": \"Chemical\"}, {\"text\": \"nephrolithiasis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00038", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The results indicate that Li - induced nephropathy, even when the GFR is only modestly reduced, is associated with proteinuria and arterial systolic hypertension.", "completion": "{\"entities\": [{\"text\": \"Li\", \"type\": \"Chemical\"}, {\"text\": \"nephropathy\", \"type\": \"Disease\"}, {\"text\": \"proteinuria\", \"type\": \"Disease\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00891", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Diffuse intramural vasoconstriction is not consistent with reports of segmental, discrete infarction.", "completion": "{\"entities\": [{\"text\": \"infarction\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03733", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Seizure activity due to PTZ and picrotoxin (PTX) was significantly decreased; however, seizure activity due to 3-mercaptopropionic acid (MPA ), bicuculline (BCC ), methyl 6,7-dimethoxy-4-ethyl-B-carboline-3-carboxylate (DMCM ), or strychnine (STR) was not different from control.", "completion": "{\"entities\": [{\"text\": \"Seizure\", \"type\": \"Disease\"}, {\"text\": \"PTZ\", \"type\": \"Chemical\"}, {\"text\": \"picrotoxin\", \"type\": \"Chemical\"}, {\"text\": \"PTX\", \"type\": \"Chemical\"}, {\"text\": \"seizure\", \"type\": \"Disease\"}, {\"text\": \"3-mercaptopropionic acid\", \"type\": \"Chemical\"}, {\"text\": \"MPA\", \"type\": \"Chemical\"}, {\"text\": \"bicuculline\", \"type\": \"Chemical\"}, {\"text\": \"BCC\", \"type\": \"Chemical\"}, {\"text\": \"methyl 6,7-dimethoxy-4-ethyl-B-carboline-3-carboxylate\", \"type\": \"Chemical\"}, {\"text\": \"DMCM\", \"type\": \"Chemical\"}, {\"text\": \"strychnine\", \"type\": \"Chemical\"}, {\"text\": \"STR\", \"type\": \"Chemical\"}]}", "n_entities": 13}
{"ref": "bc5cdr-train-01635", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Encephalopathy induced by levetiracetam added to valproate.", "completion": "{\"entities\": [{\"text\": \"Encephalopathy\", \"type\": \"Disease\"}, {\"text\": \"levetiracetam\", \"type\": \"Chemical\"}, {\"text\": \"valproate\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01579", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Further long - term analysis of renal allograft studies using sirolimus", "completion": "{\"entities\": [{\"text\": \"sirolimus\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01180", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 6 %. The median follow - up period was 14 months.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00530", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 1 (95 percent confidence interval, 1.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01269", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In addition to their effects on spasticity, certain adverse cardiorespiratory effects have been reported.", "completion": "{\"entities\": [{\"text\": \"spasticity\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00588", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In conclusion, the fact that plasma CGRP concentration correlates with the timing and severity of a migraine headache suggests a direct relationship between CGRP and migraine.", "completion": "{\"entities\": [{\"text\": \"CGRP\", \"type\": \"Chemical\"}, {\"text\": \"migraine\", \"type\": \"Disease\"}, {\"text\": \"headache\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00190", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The possible contribution of the triazolo", "completion": "{\"entities\": [{\"text\": \"triazolo\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02123", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 microM TAM induces total hemolysis of all tested suspensions.", "completion": "{\"entities\": [{\"text\": \"TAM\", \"type\": \"Chemical\"}, {\"text\": \"hemolysis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04975", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The incidence of venous discomfort was lower in Group L (76.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03542", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 001 ). These parameters remained unchanged in controls.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-05003", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Studies in DBA / 2J mice showed that: 1) pretreatment with acetaminophen (100 mg / kg) increased the interval between the administration of caffeine (300 to 450 mg / kg IP) and the onset of fatal convulsions by a factor of about two; and 2) pretreatment with acetaminophen (75 mg / kg) reduced the incidence of audiogenic seizures produced in the presence of caffeine (12.", "completion": "{\"entities\": [{\"text\": \"acetaminophen\", \"type\": \"Chemical\"}, {\"text\": \"caffeine\", \"type\": \"Chemical\"}, {\"text\": \"convulsions\", \"type\": \"Disease\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00825", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The mortality rate among patients with ATT - ALF was high (67.", "completion": "{\"entities\": [{\"text\": \"ALF\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00950", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Five patients receiving fluoxetine for the treatment of obsessive compulsive disorder or major depression developed akathisia.", "completion": "{\"entities\": [{\"text\": \"fluoxetine\", \"type\": \"Chemical\"}, {\"text\": \"obsessive compulsive disorder\", \"type\": \"Disease\"}, {\"text\": \"major depression\", \"type\": \"Disease\"}, {\"text\": \"akathisia\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03373", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: L-DOPA - induced dyskinesia (LID) is among the motor complications that arise in Parkinson's disease (PD) patients after a prolonged treatment with L-DOPA.", "completion": "{\"entities\": [{\"text\": \"L-DOPA\", \"type\": \"Chemical\"}, {\"text\": \"dyskinesia\", \"type\": \"Disease\"}, {\"text\": \"LID\", \"type\": \"Disease\"}, {\"text\": \"Parkinson's disease\", \"type\": \"Disease\"}, {\"text\": \"PD\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-01270", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Adults chronically treated with angiotensin converting enzyme inhibitors may have a limited ability to respond to hypotension when the sympathetic response is simultaneously blocked.", "completion": "{\"entities\": [{\"text\": \"angiotensin\", \"type\": \"Chemical\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01443", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Ovx significantly enhanced the hypotensive response to alpha-methyldopa, in contrast to no effect on rilmenidine hypotension.", "completion": "{\"entities\": [{\"text\": \"hypotensive\", \"type\": \"Disease\"}, {\"text\": \"alpha-methyldopa\", \"type\": \"Chemical\"}, {\"text\": \"rilmenidine\", \"type\": \"Chemical\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01558", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: OBJECTIVES: To study the long - term effects of androgen treatment on atherosclerosis in postmenopausal women.", "completion": "{\"entities\": [{\"text\": \"atherosclerosis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00070", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This toxicity appeared in patients receiving the higher doses of desferrioxamine or coincided with the normalization of ferritin or aluminium serum levels.", "completion": "{\"entities\": [{\"text\": \"toxicity\", \"type\": \"Disease\"}, {\"text\": \"desferrioxamine\", \"type\": \"Chemical\"}, {\"text\": \"aluminium\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01734", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Dopamine D2 receptors were elevated in the striatum, whereas serotonin 2C, but not serotonin 1A, receptors were elevated in the orbital frontal cortex.", "completion": "{\"entities\": [{\"text\": \"Dopamine\", \"type\": \"Chemical\"}, {\"text\": \"serotonin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04010", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A further deterioration was seen when CsA was combined with either FK506 or SRL, whereas the GFR remained unchanged in the group treated with FK506 plus SRL when compared with treatment with any of the single substances.", "completion": "{\"entities\": [{\"text\": \"CsA\", \"type\": \"Chemical\"}, {\"text\": \"FK506\", \"type\": \"Chemical\"}, {\"text\": \"SRL\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03759", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Further testing in this and other tumour", "completion": "{\"entities\": [{\"text\": \"tumour\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04013", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 001 compared with controls) and the analysis of the total grade of fibrosis also showed the highest proportion in the same group and was significantly different from controls (P < 0.", "completion": "{\"entities\": [{\"text\": \"fibrosis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01447", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These findings suggest that estrogen downregulates alpha2 - but not I1 - receptor - mediated hypotension and highlight a role for the cardiac autonomic control in alpha-methyldopa - estrogen", "completion": "{\"entities\": [{\"text\": \"estrogen\", \"type\": \"Chemical\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}, {\"text\": \"alpha-methyldopa\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02433", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We report 3 cases of serious bleeding complications that appear to be the result of the interaction between warfarin and levofloxacin.", "completion": "{\"entities\": [{\"text\": \"bleeding\", \"type\": \"Disease\"}, {\"text\": \"warfarin\", \"type\": \"Chemical\"}, {\"text\": \"levofloxacin\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04159", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: For low - dose nimodipine, the results were not conclusive.", "completion": "{\"entities\": [{\"text\": \"nimodipine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00409", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These immunohistochemical changes of NFs can serve as a marker for axonal damage in various experimental traumatic", "completion": "{\"entities\": [{\"text\": \"axonal damage\", \"type\": \"Disease\"}, {\"text\": \"traumatic\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00326", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Beginning at 8 days of age, body movement and hearing were examined for 6 and up to 17 weeks, respectively.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02773", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 4 points (range, 5 to 10 points ), reflecting minimal or no pain during fracture reduction.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"fracture\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02120", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This work evaluates the effects of TAM on isolated human erythrocytes, attempting to identify the underlying mechanisms on TAM - induced hemolytic anemia and the involvement of biomembranes in its cytostatic action mechanisms.", "completion": "{\"entities\": [{\"text\": \"TAM\", \"type\": \"Chemical\"}, {\"text\": \"hemolytic anemia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05121", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The outcomes were compared for both groups.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01784", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Locomotor activity was assessed in male Sprague - Dawley rats tested in photocell cages.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00830", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSION: ATT - ALF constituted 5.", "completion": "{\"entities\": [{\"text\": \"ALF\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01909", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Improvements were seen in the number of tender joints, the severity of swelling and tenderness, the time of walk 50 feet, the duration of morning stiffness and the circumference of the left knee.", "completion": "{\"entities\": [{\"text\": \"tender joints\", \"type\": \"Disease\"}, {\"text\": \"swelling\", \"type\": \"Disease\"}, {\"text\": \"tenderness\", \"type\": \"Disease\"}, {\"text\": \"morning stiffness\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03876", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Fanconi syndrome, as well as myopathy, is well recognized in patients with mitochondrial disorders and caused by depletion of mtDNA.", "completion": "{\"entities\": [{\"text\": \"Fanconi syndrome\", \"type\": \"Disease\"}, {\"text\": \"myopathy\", \"type\": \"Disease\"}, {\"text\": \"mitochondrial disorders\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01315", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A better controlled regimen for administering vincristine", "completion": "{\"entities\": [{\"text\": \"vincristine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03656", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 9 ), and diaphragmatic hernia (AOR = 2.", "completion": "{\"entities\": [{\"text\": \"diaphragmatic hernia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05000", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Reduction in caffeine toxicity by acetaminophen.", "completion": "{\"entities\": [{\"text\": \"caffeine\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}, {\"text\": \"acetaminophen\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00166", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Although the AE RBCs from an individual not taking dapsone had increased incubated Heinz body formation, the GSH content and GSH stability were normal.", "completion": "{\"entities\": [{\"text\": \"dapsone\", \"type\": \"Chemical\"}, {\"text\": \"GSH\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03100", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Assessment of a new non - invasive index of cardiac performance for detection of dobutamine - induced myocardial ischemia.", "completion": "{\"entities\": [{\"text\": \"dobutamine\", \"type\": \"Chemical\"}, {\"text\": \"myocardial ischemia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04696", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cervical and inguinal lymph node biopsies showed the features of severe necrotising lymphadenitis, associated with erythrophagocytosis and prominent eosinophilic infiltrates, without viral inclusion bodies, suggestive of an adverse drug reaction.", "completion": "{\"entities\": [{\"text\": \"lymphadenitis\", \"type\": \"Disease\"}, {\"text\": \"adverse drug reaction\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00812", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 8 %) patients, ATT was prescribed empirically without definitive evidence of tuberculosis.", "completion": "{\"entities\": [{\"text\": \"tuberculosis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03005", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Blood and urine cultures did not show any bacterial growth.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04427", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: The expression of MRP2 and Pgp in brain and liver sections of TR (-) rats and normal Wistar rats was determined with immunohistochemistry, by using a novel, highly selective monoclonal MRP2 antibody and the monoclonal Pgp antibody C219, respectively.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00300", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The cell populations were examined regarding total cell recovery correlated with gland weight, intracellular prolactin (PRL) content and subsequent release in primary culture, immunocytochemical PRL staining, density and / or size alterations via separation on Ficoll - Hypaque and by unit gravity sedimentation, and cell cycle analysis, after acriflavine DNA staining, by laser flow cytometry.", "completion": "{\"entities\": [{\"text\": \"acriflavine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02515", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thirty PD patients participated in the study.", "completion": "{\"entities\": [{\"text\": \"PD\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00260", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Sensori-motor neuropathy was the commonest presentation (50 %). Guillain-Barr syndrome was the commonest identifiable cause (15.", "completion": "{\"entities\": [{\"text\": \"Sensori-motor neuropathy\", \"type\": \"Disease\"}, {\"text\": \"Guillain-Barr syndrome\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02260", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The aggravated risk on intracerebral hemorrhage (ICH) with drugs used for stroke patients should be estimated carefully.", "completion": "{\"entities\": [{\"text\": \"intracerebral hemorrhage\", \"type\": \"Disease\"}, {\"text\": \"ICH\", \"type\": \"Disease\"}, {\"text\": \"stroke\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00327", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Abnormal movements and deafness occurred only in rats treated during the preweaning period; within this period the greatest sensitivities for these abnormalities occurred from 2 to 11 - 17 and 5 to 11 days of age, respectively, indicating that the cochlea is more sensitive to streptomycin than the site (vestibular or central) responsible for the dyskinesias", "completion": "{\"entities\": [{\"text\": \"Abnormal movements\", \"type\": \"Disease\"}, {\"text\": \"deafness\", \"type\": \"Disease\"}, {\"text\": \"streptomycin\", \"type\": \"Chemical\"}, {\"text\": \"dyskinesias\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01102", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RAST for BPO-PLL and AX - PLL was done.", "completion": "{\"entities\": [{\"text\": \"BPO-PLL\", \"type\": \"Chemical\"}, {\"text\": \"AX\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02235", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 001 ). Antinociceptive effect of morphine was reduced in chronically treated rats (39 +/- 10 vs.", "completion": "{\"entities\": [{\"text\": \"morphine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03609", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After a 30 - min baseline measure of locomotor activity (day 0 ), animals were maintained on a cyclic diet of 12 - h deprivation followed by 12 - h access to 10% sucrose solution and chow pellets (12 h access starting 4 h after onset of the dark period) for 21 days.", "completion": "{\"entities\": [{\"text\": \"sucrose\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02546", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: One patient showed no recovery of later waves and a delayed profound sensorineural hearing loss.", "completion": "{\"entities\": [{\"text\": \"sensorineural hearing loss\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00490", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: bipolar II ), and additional treatment did not affect the risk of switching.", "completion": "{\"entities\": [{\"text\": \"bipolar II\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00333", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This report documents the unusual occurrence of rapidly progressive glomerulonephritis with crescents and fibrillar glomerulonephritis in a patient treated with rifampin", "completion": "{\"entities\": [{\"text\": \"glomerulonephritis\", \"type\": \"Disease\"}, {\"text\": \"rifampin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03989", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSION: Both selective and non - selective COX - 2 inhibitors were toxic for rats fetuses when administered in the highest dose.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04666", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 3% for ergotamine / caffeine (p < or = 0.", "completion": "{\"entities\": [{\"text\": \"ergotamine\", \"type\": \"Chemical\"}, {\"text\": \"caffeine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-00666", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Adverse gastrointestinal effects were uncommon.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00890", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Although certain clinical and experimental findings support the hypothesis that spasm involves the epicardial, medium - size vessels, other data suggest intramural vasoconstriction.", "completion": "{\"entities\": [{\"text\": \"spasm\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01953", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The frequency of visual loss decreased after the concentration of the ethanol", "completion": "{\"entities\": [{\"text\": \"visual loss\", \"type\": \"Disease\"}, {\"text\": \"ethanol\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00066", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Moreover, detailed ophthalmologic and audiologic studies disclosed abnormalities in 7 more asymptomatic patients.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02451", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: To this end, persistent hyperalgesia was induced by administration of capsaicin in the tail of gonadally intact F344 rats, following which the tail was immersed in a mildly noxious thermal stimulus, and tail - withdrawal latencies measured.", "completion": "{\"entities\": [{\"text\": \"hyperalgesia\", \"type\": \"Disease\"}, {\"text\": \"capsaicin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00941", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: As an alpha - blocker, it also exerts a significant relaxant effect on the bladder neck and urethra.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02072", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The aim of this study was to describe this hearing loss and to investigate other factors influencing the degree of hearing loss.", "completion": "{\"entities\": [{\"text\": \"hearing loss\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01599", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: Direct inhibition of cardiac HCN pacemaker channels contributes to the bradycardic effects of clonidine gene - targeted mice in vivo, and thus, clonidine", "completion": "{\"entities\": [{\"text\": \"clonidine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02359", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We consider drug - induced cerebral vasculitis as the most likely cause of recurrent ischaemic strokes in the absence of any pathological findings during the diagnostic work - up.", "completion": "{\"entities\": [{\"text\": \"cerebral vasculitis\", \"type\": \"Disease\"}, {\"text\": \"ischaemic strokes\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02930", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Health status and MHb levels were monitored following exposure.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01572", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Its role in the therapy of glomerulonephritis, autoimmunity, cystic renal diseases and renal cancer is under investigation.", "completion": "{\"entities\": [{\"text\": \"glomerulonephritis\", \"type\": \"Disease\"}, {\"text\": \"autoimmunity\", \"type\": \"Disease\"}, {\"text\": \"cystic renal diseases\", \"type\": \"Disease\"}, {\"text\": \"renal cancer\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04000", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Kidney function and morphology after short - term combination therapy with cyclosporine A, tacrolimus and sirolimus in the rat.", "completion": "{\"entities\": [{\"text\": \"cyclosporine A\", \"type\": \"Chemical\"}, {\"text\": \"tacrolimus\", \"type\": \"Chemical\"}, {\"text\": \"sirolimus\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04342", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 01) in intima and media for CaCl(2) - treated segments.", "completion": "{\"entities\": [{\"text\": \"CaCl(2)\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00296", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It is therefore suggested that caution should be exercised when prescribing vasodilator drugs in diabetic patients, particularly those with autonomic neuropathy", "completion": "{\"entities\": [{\"text\": \"diabetic\", \"type\": \"Disease\"}, {\"text\": \"autonomic neuropathy\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01192", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Plasma sodium concentrations were found to be slightly increased in the Li - treated rats compared with those in controls.", "completion": "{\"entities\": [{\"text\": \"sodium\", \"type\": \"Chemical\"}, {\"text\": \"Li\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04187", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Finally, the dose response for cardiovascular events of nicotine appears to be flat, suggesting that if nicotine", "completion": "{\"entities\": [{\"text\": \"nicotine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05160", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: c .) every other day for 3 days caused a significant increase in vacuous chewing, tongue protrusion and duration of facial twitching, compared to the control.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04673", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 001 ). Recurrence rates were 31.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04966", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: min - 1 ). Loss of consciousness occurred in 60 - 90 sec.", "completion": "{\"entities\": [{\"text\": \"Loss of consciousness\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00648", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5) g / d before conversion to 3.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00852", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: Behavioral experiments and electrophysiological recordings were performed in the present study.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04278", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Although generally consisted safe when given intramuscularly, intravenous administration is known to cause respiratory and cardiovascular depression.", "completion": "{\"entities\": [{\"text\": \"respiratory and cardiovascular depression\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00505", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After 35 days in the TG + HAART cohort, left ventricular mass increased 160% by echocardiography.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02236", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 18 +/- 5 au) while the combination - induced antinociception was remained similar as an acute treatment (298 +/- 7 vs.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00577", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Fifteen female migraineurs (without aura) and eight controls participated in the study.", "completion": "{\"entities\": [{\"text\": \"migraineurs (without aura)\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00245", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The timolol - related increase in heart size was observed only in patients with normal and borderline heart size.", "completion": "{\"entities\": [{\"text\": \"timolol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04849", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The findings suggest that curcumin can be considered as a potential safe and effective adjuvant to phenobarbitone and carbamazepine therapy in preventing cognitive impairment", "completion": "{\"entities\": [{\"text\": \"curcumin\", \"type\": \"Chemical\"}, {\"text\": \"phenobarbitone\", \"type\": \"Chemical\"}, {\"text\": \"carbamazepine\", \"type\": \"Chemical\"}, {\"text\": \"cognitive impairment\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02532", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 01) at the second transthoracic echocardiography and the two patients with heart failure returned to nearly normal clinical examination.", "completion": "{\"entities\": [{\"text\": \"heart failure\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03243", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: l (- 1) when the end - tidal concentration of sevoflurane was 0.", "completion": "{\"entities\": [{\"text\": \"sevoflurane\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-reassigned-05415", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHOD: A clinical case description.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04759", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We report the first case of a serious short - term adverse reaction with the use of omeprazole: hemolytic anemia.", "completion": "{\"entities\": [{\"text\": \"omeprazole\", \"type\": \"Chemical\"}, {\"text\": \"hemolytic anemia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01168", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Treatment of previously treated metastatic breast cancer by mitoxantrone and 48 - hour continuous infusion of high - dose 5-FU and leucovorin (MFL ): low palliative benefit and high treatment - related toxicity.", "completion": "{\"entities\": [{\"text\": \"breast cancer\", \"type\": \"Disease\"}, {\"text\": \"mitoxantrone\", \"type\": \"Chemical\"}, {\"text\": \"5-FU\", \"type\": \"Chemical\"}, {\"text\": \"leucovorin\", \"type\": \"Chemical\"}, {\"text\": \"MFL\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-03296", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: ROIs drawn over the gamma camera images showed a ratio of 4.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04369", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: On a low - salt (LS) diet, male DS had higher levels of intrarenal angiotensinogen mRNA than females.", "completion": "{\"entities\": [{\"text\": \"salt\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02454", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Across the doses and pretreatment times examined, enhancement was not observed in females.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03021", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: OBJECTIVE: The outcome of subarachnoid hemorrhage associated with cocaine abuse is reportedly poor.", "completion": "{\"entities\": [{\"text\": \"subarachnoid hemorrhage\", \"type\": \"Disease\"}, {\"text\": \"cocaine abuse\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03797", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A selective dopamine D4 receptor antagonist, NRA0160: a preclinical neuropharmacological profile.", "completion": "{\"entities\": [{\"text\": \"dopamine\", \"type\": \"Chemical\"}, {\"text\": \"NRA0160\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03251", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The rise in blood pressure became less marked when higher concentrations of sevoflurane or enflurane were administered and the blood pressure at convulsions decreased significantly in 1.", "completion": "{\"entities\": [{\"text\": \"sevoflurane\", \"type\": \"Chemical\"}, {\"text\": \"enflurane\", \"type\": \"Chemical\"}, {\"text\": \"convulsions\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02731", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05) and glomerular capillary pressure (54 +/- 1 vs.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04422", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Upregulation of brain expression of P - glycoprotein in MRP2 - deficient TR (-) rats resembles seizure - induced up - regulation of this drug efflux transporter in normal rats.", "completion": "{\"entities\": [{\"text\": \"seizure\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-reassigned-05178", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Three patients (8.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01293", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pharmacokinetic / pharmacodynamic assessment of the effects of E4031, cisapride, terfenadine and terodiline on monophasic action potential duration in dog.", "completion": "{\"entities\": [{\"text\": \"E4031\", \"type\": \"Chemical\"}, {\"text\": \"cisapride\", \"type\": \"Chemical\"}, {\"text\": \"terfenadine\", \"type\": \"Chemical\"}, {\"text\": \"terodiline\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03848", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The patient with nitrazepam overdose and two of those with chlormethiazole intoxication conformed to the criteria of' alpha coma ', showing non - reactive generalized or frontally predominant alpha activity in the EEG.", "completion": "{\"entities\": [{\"text\": \"nitrazepam\", \"type\": \"Chemical\"}, {\"text\": \"overdose\", \"type\": \"Disease\"}, {\"text\": \"chlormethiazole\", \"type\": \"Chemical\"}, {\"text\": \"coma\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03402", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Among 547 preterm infants of < or = 34 weeks gestation born between 1987 and 1991, 8 children (1.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-reassigned-04034", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 14, 95% confidence interval [CI ]: 1.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02987", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: INTERVENTION: Each patient received either intravenous docetaxel 30 mg / m2 / week for 3 consecutive weeks, followed by 1 week off, or the combination of continuous oral thalidomide 200 mg every evening plus the same docetaxel regimen.", "completion": "{\"entities\": [{\"text\": \"docetaxel\", \"type\": \"Chemical\"}, {\"text\": \"thalidomide\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02349", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Aminoglycoside antibiotics are still widely used by virtue of their efficacy and low cost.", "completion": "{\"entities\": [{\"text\": \"Aminoglycoside\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05205", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In this study, three Chinese patients with ticlopidine - induced aplastic anemia were reported and another 13 patients in the English literature were reviewed.", "completion": "{\"entities\": [{\"text\": \"ticlopidine\", \"type\": \"Chemical\"}, {\"text\": \"aplastic anemia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02632", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Post hoc analyses indicated that efficacy was similar with asenapine and haloperidol; greater contrasts were seen in AEs, especially extrapyramidal symptoms", "completion": "{\"entities\": [{\"text\": \"asenapine\", \"type\": \"Chemical\"}, {\"text\": \"haloperidol\", \"type\": \"Chemical\"}, {\"text\": \"extrapyramidal symptoms\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02477", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 25 ), whereas patients who developed high - grade proteinuria showed decreased renal function at the end of follow - up (median 39.", "completion": "{\"entities\": [{\"text\": \"proteinuria\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03516", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The aim of this study was to evaluate the relationship between phenytoin medication and cerebellar atrophy in patients who had experienced clinical intoxication.", "completion": "{\"entities\": [{\"text\": \"phenytoin\", \"type\": \"Chemical\"}, {\"text\": \"cerebellar atrophy\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01714", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 mg kg (- 1 )), 13 patients received phenylephrine (0.", "completion": "{\"entities\": [{\"text\": \"phenylephrine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04683", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Five patients with carcinoma developed thrombotic microangiopathy (characterized by renal insufficiency, microangiopathic hemolytic anemia, and usually thrombocytopenia) after treatment with cisplatin, bleomycin, and a vinca alkaloid.", "completion": "{\"entities\": [{\"text\": \"carcinoma\", \"type\": \"Disease\"}, {\"text\": \"thrombotic microangiopathy\", \"type\": \"Disease\"}, {\"text\": \"renal insufficiency\", \"type\": \"Disease\"}, {\"text\": \"microangiopathic hemolytic anemia\", \"type\": \"Disease\"}, {\"text\": \"thrombocytopenia\", \"type\": \"Disease\"}, {\"text\": \"cisplatin\", \"type\": \"Chemical\"}, {\"text\": \"bleomycin\", \"type\": \"Chemical\"}, {\"text\": \"vinca alkaloid\", \"type\": \"Chemical\"}]}", "n_entities": 8}
{"ref": "bc5cdr-train-02283", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: Incidence and risk factors for delirium during clozapine treatment require further clarification.", "completion": "{\"entities\": [{\"text\": \"delirium\", \"type\": \"Disease\"}, {\"text\": \"clozapine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03644", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 8 ), hypoplastic left heart syndrome (AOR = 3.", "completion": "{\"entities\": [{\"text\": \"hypoplastic left heart syndrome\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03071", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The underlying mechanism of withdrawal-emergent RS in the present case may have been related to the pharmacological profile of risperidone, a serotonin - dopamine antagonist, suggesting the pathophysiologic influence of the serotonin system in the development of RS", "completion": "{\"entities\": [{\"text\": \"withdrawal-emergent RS\", \"type\": \"Disease\"}, {\"text\": \"RS\", \"type\": \"Disease\"}, {\"text\": \"risperidone\", \"type\": \"Chemical\"}, {\"text\": \"serotonin\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-04198", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Two groups of patients receiving tacrolimus were compared over a period of 1 year, one group comprising hypertensive patients who were receiving nifedipine, and the other comprising nonhypertensive patients not receiving nifedipine.", "completion": "{\"entities\": [{\"text\": \"tacrolimus\", \"type\": \"Chemical\"}, {\"text\": \"hypertensive\", \"type\": \"Disease\"}, {\"text\": \"nifedipine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01993", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The efficacy of alprazolam and placebo in panic disorder with agoraphobia, and the side - effect and adverse effect profiles of both drug groups were measured.", "completion": "{\"entities\": [{\"text\": \"alprazolam\", \"type\": \"Chemical\"}, {\"text\": \"panic disorder\", \"type\": \"Disease\"}, {\"text\": \"agoraphobia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03809", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: NRA0160 and clozapine significantly induced catalepsy in rats, although their effects did not exceed 50% induction even at the highest dose given.", "completion": "{\"entities\": [{\"text\": \"NRA0160\", \"type\": \"Chemical\"}, {\"text\": \"clozapine\", \"type\": \"Chemical\"}, {\"text\": \"catalepsy\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04845", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The administration of phenobarbitone and carbamazepine for 21days caused a significant impairment of learning and memory as well as an increased oxidative stress.", "completion": "{\"entities\": [{\"text\": \"phenobarbitone\", \"type\": \"Chemical\"}, {\"text\": \"carbamazepine\", \"type\": \"Chemical\"}, {\"text\": \"impairment of learning and memory\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00519", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: An analysis for factor V Leiden and the G20210A mutation in the prothrombin gene was conducted in 217 patients and 763 controls RESULTS: The odds ratio for myocardial infarction among women who used any type of combined oral contraceptive, as compared with nonusers, was 2.", "completion": "{\"entities\": [{\"text\": \"myocardial infarction\", \"type\": \"Disease\"}, {\"text\": \"oral contraceptive\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02604", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Participants underwent polysomnographic sleep recordings on days 1 to 3, 7 to 9, and 14 to 16 (first, second, and third weeks of abstinence ). The Multiple Sleep Latency Test was performed at 11: 30 a.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02304", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: All complaints faded away within 24 h.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04732", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pretreatment with L - NOArg and L - NIL but not 7 - NI, significantly increases antihyperalgesic activity both HOE 140 and des Arg10 HOE 140.", "completion": "{\"entities\": [{\"text\": \"HOE 140\", \"type\": \"Chemical\"}, {\"text\": \"des Arg10 HOE 140\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02008", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A total of 38 consecutive patients who presented to our clinic with impotence received 0.", "completion": "{\"entities\": [{\"text\": \"impotence\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04108", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Spironolactone - induced renal insufficiency and hyperkalemia in patients with heart failure.", "completion": "{\"entities\": [{\"text\": \"Spironolactone\", \"type\": \"Chemical\"}, {\"text\": \"renal insufficiency\", \"type\": \"Disease\"}, {\"text\": \"hyperkalemia\", \"type\": \"Disease\"}, {\"text\": \"heart failure\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04424", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: By using this strategy to study the involvement of MRP2 in brain access of antiepileptic drugs (AEDs ), we recently reported that phenytoin is a substrate for MRP2 in the BBB.", "completion": "{\"entities\": [{\"text\": \"phenytoin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02843", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pain rating was performed using a computerized visual analogue scale (0 - 100) digitized at 1 / s, either immediately online or one hour or one day after injection.", "completion": "{\"entities\": [{\"text\": \"Pain\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04839", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Curcumin has shown antioxidant, anti - inflammatory and neuro - protective properties.", "completion": "{\"entities\": [{\"text\": \"Curcumin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00257", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Diseases of peripheral nerves as seen in the Nigerian African.", "completion": "{\"entities\": [{\"text\": \"Diseases of peripheral nerves\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04413", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Briefly, cells were differentiated for 72 h with 100 nM PMA to obtain a macrophage - like phenotype in the presence or absence of 1 nM 17beta-estradiol (E2 ), 100 nM progesterone or vehicle (0.", "completion": "{\"entities\": [{\"text\": \"17beta-estradiol\", \"type\": \"Chemical\"}, {\"text\": \"E2\", \"type\": \"Chemical\"}, {\"text\": \"progesterone\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-05019", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In patients with unstable angina, flestolol infusion was found to be safe and effective in controlling chest pain.", "completion": "{\"entities\": [{\"text\": \"unstable angina\", \"type\": \"Disease\"}, {\"text\": \"flestolol\", \"type\": \"Chemical\"}, {\"text\": \"chest pain\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04401", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Sulpiride induced only SOCS - 1 in the medial preoptic area, where GnRH neurons are regulated, but in the arcuate nucleus and choroid plexus, PRL - R, SOCS - 3, and CIS mRNA levels were also induced.", "completion": "{\"entities\": [{\"text\": \"Sulpiride\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03871", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Tacrolimus, MMF, and steroids were given as immunosuppressant.", "completion": "{\"entities\": [{\"text\": \"Tacrolimus\", \"type\": \"Chemical\"}, {\"text\": \"MMF\", \"type\": \"Chemical\"}, {\"text\": \"steroids\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-05061", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: On the other hand, pretreatment with p-chlorophenylalamine (3 X 320 mg / kg i.", "completion": "{\"entities\": [{\"text\": \"p-chlorophenylalamine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03101", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: Electrocardiography has a very low sensitivity in detecting dobutamine - induced myocardial ischemia.", "completion": "{\"entities\": [{\"text\": \"dobutamine\", \"type\": \"Chemical\"}, {\"text\": \"myocardial ischemia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03010", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It is likely that this complication will be seen more often with the increased worldwide use of this drug and its approval for all arteriopathic", "completion": "{\"entities\": [{\"text\": \"arteriopathic\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01791", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The effect appears to be mediated by central nicotine receptors, possibly located on dopaminergic neurons, and also requires the activation of both D1 and D2 dopamine", "completion": "{\"entities\": [{\"text\": \"nicotine\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00318", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A possible involvement of energy metabolism was suggested previously, and in this study the adenylate energy charge and phosphorylcreatine mole fraction were determined in the adriamycin - treated cells.", "completion": "{\"entities\": [{\"text\": \"phosphorylcreatine\", \"type\": \"Chemical\"}, {\"text\": \"adriamycin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03714", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Maximum tolerated dose in good - risk patients was 70 mg / m2, and in poor - risk patients, 60 mg / m2.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04788", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Future research with larger number of patients is needed to find out modifiable factors that will improve the safety of ribavirin", "completion": "{\"entities\": [{\"text\": \"ribavirin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01877", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In five rats that did not become rigid, ICP and CVP did not change following alfentanil.", "completion": "{\"entities\": [{\"text\": \"alfentanil\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02274", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Estrogens protect ovariectomized rats from hippocampal injury induced by kainic acid - induced status epilepticus (SE ). We compared the effects of 17beta-estradiol in adult male and ovariectomized female rats subjected to lithium - pilocarpine - induced SE.", "completion": "{\"entities\": [{\"text\": \"hippocampal injury\", \"type\": \"Disease\"}, {\"text\": \"kainic acid\", \"type\": \"Chemical\"}, {\"text\": \"status epilepticus\", \"type\": \"Disease\"}, {\"text\": \"SE\", \"type\": \"Disease\"}, {\"text\": \"17beta-estradiol\", \"type\": \"Chemical\"}, {\"text\": \"lithium\", \"type\": \"Chemical\"}, {\"text\": \"pilocarpine\", \"type\": \"Chemical\"}]}", "n_entities": 7}
{"ref": "bc5cdr-train-01001", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 75 %(plus 67% nitrous oxide in oxygen ), during which CBF and CMRO2 were 34.", "completion": "{\"entities\": [{\"text\": \"nitrous oxide\", \"type\": \"Chemical\"}, {\"text\": \"oxygen\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02151", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In control rats, intravenous bromocriptine (150 microg / kg) induced significant hypotension and tachycardia.", "completion": "{\"entities\": [{\"text\": \"bromocriptine\", \"type\": \"Chemical\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}, {\"text\": \"tachycardia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01967", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Rc seemed to be independent of age and decreased with increasing serum concentration of cimetidine, suggesting that secretion of cimetidine is a saturable process.", "completion": "{\"entities\": [{\"text\": \"cimetidine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02880", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Contact with the skin can result in percutaneous absorption of the substance that inhibits aldehyde dehydrogenase and can induce acetaldehyde syndrome in case of alcohol use.", "completion": "{\"entities\": [{\"text\": \"aldehyde\", \"type\": \"Chemical\"}, {\"text\": \"acetaldehyde\", \"type\": \"Chemical\"}, {\"text\": \"alcohol\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02656", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Differences in the parameters of training under the influence of pentobarbital between Groups 1 and 2 were revealed.", "completion": "{\"entities\": [{\"text\": \"pentobarbital\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00494", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We describe a 25 - year - old woman with pre - existing mitral valve prolapse who developed intractable ventricular fibrillation after consuming a\" natural energy\" guarana health drink containing a high concentration of caffeine", "completion": "{\"entities\": [{\"text\": \"mitral valve prolapse\", \"type\": \"Disease\"}, {\"text\": \"ventricular fibrillation\", \"type\": \"Disease\"}, {\"text\": \"caffeine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02706", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A comprehensive examination including her medical history, panoramic radiograph, and intraoral examination revealed 19 carious lesions, which is not very common for a healthy adult.", "completion": "{\"entities\": [{\"text\": \"carious lesions\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00303", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 9 times control values by day 150.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03633", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Five patients were diagnosed as having subclinical heart failure after the completion of chemotherapy.", "completion": "{\"entities\": [{\"text\": \"heart failure\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00793", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In both ecstasy and cannabis groups brain activation was decreased in the right medial frontal gyrus, left parahippocampal gyrus, left dorsal cingulate gyrus, and left caudate.", "completion": "{\"entities\": [{\"text\": \"ecstasy\", \"type\": \"Chemical\"}, {\"text\": \"cannabis\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00094", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This is not consistent with a CNS origin of migraine", "completion": "{\"entities\": [{\"text\": \"migraine\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03353", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A selective antagonist of mGluR5, 2-methyl-6-(phenylethynyl)pyridine (MPEP; 5 mg / kg ip ), when administered five times immediately before each methamphetamine injection reversed the above - mentioned methamphetamine effects.", "completion": "{\"entities\": [{\"text\": \"2-methyl-6-(phenylethynyl)pyridine\", \"type\": \"Chemical\"}, {\"text\": \"MPEP\", \"type\": \"Chemical\"}, {\"text\": \"methamphetamine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03685", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Jaundice with tender hepatomegaly, usually preceded by symptoms of malaise, anorexia, nausea and vomiting, and associated with upper abdominal pain, was an invariable finding in all patients.", "completion": "{\"entities\": [{\"text\": \"Jaundice\", \"type\": \"Disease\"}, {\"text\": \"hepatomegaly\", \"type\": \"Disease\"}, {\"text\": \"anorexia\", \"type\": \"Disease\"}, {\"text\": \"nausea\", \"type\": \"Disease\"}, {\"text\": \"vomiting\", \"type\": \"Disease\"}, {\"text\": \"abdominal pain\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-01475", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 1 ), gallbladder disease (RR 1.", "completion": "{\"entities\": [{\"text\": \"gallbladder disease\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-reassigned-01035", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Active vasculitis was noted in 36.", "completion": "{\"entities\": [{\"text\": \"vasculitis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05002", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Because salicylates have been reported to augment the stimulatory effects of caffeine on the CNS, attention was focused on the possibility that the presence of acetaminophen (52 micrograms / mL) reduced the CNS toxicity of caffeine.", "completion": "{\"entities\": [{\"text\": \"caffeine\", \"type\": \"Chemical\"}, {\"text\": \"acetaminophen\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00244", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These differences may be caused by timolol - induced bradycardia and a compensatory increase in end - diastolic volume.", "completion": "{\"entities\": [{\"text\": \"timolol\", \"type\": \"Chemical\"}, {\"text\": \"bradycardia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03846", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Four patients who were rendered comatose or stuporous by drug intoxication, but who were not hypoxic, are described.", "completion": "{\"entities\": [{\"text\": \"comatose\", \"type\": \"Disease\"}, {\"text\": \"stuporous\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01840", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 6 %), heart diseases (4.", "completion": "{\"entities\": [{\"text\": \"heart diseases\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02925", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Using this rationale, the 8-aminoquinoline WR242511, a potent long - lasting MHb former in rodents and beagle dogs, was studied in the rhesus monkey for advanced development as a potential CN pretreatment.", "completion": "{\"entities\": [{\"text\": \"8-aminoquinoline\", \"type\": \"Chemical\"}, {\"text\": \"WR242511\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00099", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This observation shows that clotiazepam can induce acute hepatitis and suggests that there is no cross hepatotoxicity between clotiazepam and several benzodiazepines", "completion": "{\"entities\": [{\"text\": \"clotiazepam\", \"type\": \"Chemical\"}, {\"text\": \"hepatitis\", \"type\": \"Disease\"}, {\"text\": \"hepatotoxicity\", \"type\": \"Disease\"}, {\"text\": \"benzodiazepines\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01971", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thus, high cimetidine levels alone do not always induce dementia", "completion": "{\"entities\": [{\"text\": \"cimetidine\", \"type\": \"Chemical\"}, {\"text\": \"dementia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00833", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Central nervous system (CNS) complications during treatment of childhood acute lymphoblastic leukemia (ALL) remain a challenging clinical problem.", "completion": "{\"entities\": [{\"text\": \"Central nervous system (CNS) complications\", \"type\": \"Disease\"}, {\"text\": \"acute lymphoblastic leukemia\", \"type\": \"Disease\"}, {\"text\": \"ALL\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01605", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Newborns whose mothers reported smoking during pregnancy (n = 200 ears) were compared to a control group of newborns (n = 200 ears ), whose mothers were non - smokers.", "completion": "{\"entities\": [{\"text\": \"smoking\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01701", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Among them are glycine transporter - 1 (GlyT1) inhibitors such as SSR103800, which indirectly enhance NMDA receptor function by increasing the glycine (a co - agonist for the NMDA receptor) levels in the synapse.", "completion": "{\"entities\": [{\"text\": \"glycine\", \"type\": \"Chemical\"}, {\"text\": \"SSR103800\", \"type\": \"Chemical\"}, {\"text\": \"NMDA\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03927", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A median of 2 cycles of therapy was administered to the 37 eligible patients.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00709", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Her vocal change and weakness began to improve spontaneously about 3 weeks after transfer.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04190", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CASE SUMMARY: A 40 - year - old woman with major depression took an overdose of venlafaxine in an apparent suicide attempt.", "completion": "{\"entities\": [{\"text\": \"major depression\", \"type\": \"Disease\"}, {\"text\": \"overdose\", \"type\": \"Disease\"}, {\"text\": \"venlafaxine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01593", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Clonidine - induced bradycardia in conscious alpha2ABC -/- mice was 32.", "completion": "{\"entities\": [{\"text\": \"Clonidine\", \"type\": \"Chemical\"}, {\"text\": \"bradycardia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03462", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 9 %). All patients recovered.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00933", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thermal enhancement ratios estimated for\" acute\" hematological changes were 1.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01393", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 75 mg, intramuscularly, every 28 days plus 250 mg flutamide, tid, per Os] and were evaluated for anemia by physical examination and laboratory tests at baseline and 4 subsequent intervals (1, 2, 3 and 6 months post - CAB ). Hb, PSA and Testosterone measurements were recorded.", "completion": "{\"entities\": [{\"text\": \"flutamide\", \"type\": \"Chemical\"}, {\"text\": \"anemia\", \"type\": \"Disease\"}, {\"text\": \"Testosterone\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03960", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Therefore, when the arrhythmia is present in this population, reversible causes must be identified and resolved.", "completion": "{\"entities\": [{\"text\": \"arrhythmia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00595", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Behavioral effects of urotensin-II centrally administered in mice.", "completion": "{\"entities\": [{\"text\": \"urotensin-II\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02964", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The circle in which the participant succeeded to aim was recorded in millimetres radius.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00957", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Although generally well - tolerated, asymptomatic abnormalities of liver function have been recorded and, less commonly, severe hepatitis induced by diclofenac.", "completion": "{\"entities\": [{\"text\": \"abnormalities of liver function\", \"type\": \"Disease\"}, {\"text\": \"hepatitis\", \"type\": \"Disease\"}, {\"text\": \"diclofenac\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04700", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It is thought that the clinico - pathological features and chronology of this case bore the hallmarks of the so - called\" 3 - week sulphasalazine syndrome \", a rare, but often fatal, immunoallergic reaction to sulphasalazine", "completion": "{\"entities\": [{\"text\": \"sulphasalazine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00969", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: For glyburide, a second - generation sulfonylurea, only two brief reports of hepatotoxicity exist.", "completion": "{\"entities\": [{\"text\": \"glyburide\", \"type\": \"Chemical\"}, {\"text\": \"sulfonylurea\", \"type\": \"Chemical\"}, {\"text\": \"hepatotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03954", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: p .)) and metrifonate (10 mg / kg, p.", "completion": "{\"entities\": [{\"text\": \"metrifonate\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01205", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: An increase in blood pressure, accompanied by atrial fibrillation, agitation, incomprehensible shouts and loss of consciousness, was observed in an elderly, ASA classification group II, cardiovascularly medicated male, 12 min after performance of axillary block with mepivacaine 850 mg containing adrenaline 0.", "completion": "{\"entities\": [{\"text\": \"increase in blood pressure\", \"type\": \"Disease\"}, {\"text\": \"atrial fibrillation\", \"type\": \"Disease\"}, {\"text\": \"agitation\", \"type\": \"Disease\"}, {\"text\": \"incomprehensible shouts\", \"type\": \"Disease\"}, {\"text\": \"loss of consciousness\", \"type\": \"Disease\"}, {\"text\": \"mepivacaine\", \"type\": \"Chemical\"}, {\"text\": \"adrenaline\", \"type\": \"Chemical\"}]}", "n_entities": 7}
{"ref": "bc5cdr-train-00434", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Effects of tetrandrine and fangchinoline on experimental thrombosis in mice and human platelet aggregation.", "completion": "{\"entities\": [{\"text\": \"tetrandrine\", \"type\": \"Chemical\"}, {\"text\": \"fangchinoline\", \"type\": \"Chemical\"}, {\"text\": \"thrombosis\", \"type\": \"Disease\"}, {\"text\": \"platelet aggregation\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02727", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Groups 1 and 2 underwent micropuncture studies after 10 days.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04625", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We report an interesting case investigating a (near) fatal poisoning.", "completion": "{\"entities\": [{\"text\": \"poisoning\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00304", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Intracellular PRL content ranged from 1.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03674", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Immunosuppressive drugs have been used during the last 30 years in treatment of patients with severe rheumatoid arthritis.", "completion": "{\"entities\": [{\"text\": \"rheumatoid arthritis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01430", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The control rats received atropine sulfate, but also saline and olive oil instead of other antidotes and DFP, respectively.", "completion": "{\"entities\": [{\"text\": \"atropine sulfate\", \"type\": \"Chemical\"}, {\"text\": \"DFP\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03765", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Alpha-lipoic acid exerts neuroprotective effects against chemotherapy induced neurotoxicity in sensory neurons: it rescues the mitochondrial toxicity and induces the expression of frataxin, an essential mitochondrial protein with anti - oxidant and chaperone properties.", "completion": "{\"entities\": [{\"text\": \"Alpha-lipoic acid\", \"type\": \"Chemical\"}, {\"text\": \"neurotoxicity\", \"type\": \"Disease\"}, {\"text\": \"mitochondrial toxicity\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03393", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Rare serious complications may occur in some patients, including haemorrhagic pancreatitis, bone marrow suppression, VPA - induced hepatotoxicity and VPA - induced encephalopathy.", "completion": "{\"entities\": [{\"text\": \"pancreatitis\", \"type\": \"Disease\"}, {\"text\": \"bone marrow suppression\", \"type\": \"Disease\"}, {\"text\": \"VPA\", \"type\": \"Chemical\"}, {\"text\": \"hepatotoxicity\", \"type\": \"Disease\"}, {\"text\": \"encephalopathy\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-04333", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Elevation of ADAM10, ADAM17, MMP - 2 and MMP - 9 expression with media degeneration features CaCl2 - induced thoracic aortic aneurysm in a rat model.", "completion": "{\"entities\": [{\"text\": \"CaCl2\", \"type\": \"Chemical\"}, {\"text\": \"thoracic aortic aneurysm\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04400", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Lastly, we measured PRL - R and suppressor of cytokine signaling (SOCS - 1 and - 3 and CIS, which reflect the level of prolactin signaling) mRNAs in response to sulpiride and estradiol.", "completion": "{\"entities\": [{\"text\": \"sulpiride\", \"type\": \"Chemical\"}, {\"text\": \"estradiol\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03701", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: With paclitaxel doses of 200 mg / m2 and higher, granulocyte colony - stimulating factor 5 micrograms / kg / d is given (days 4 through 12 ). Of 18 patients evaluable for response, seven (39 %) achieved a complete response and six (33 %) achieved a partial response.", "completion": "{\"entities\": [{\"text\": \"paclitaxel\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02310", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Both the trigeminal and the cranial parasympathetic systems may be involved in mediating these dysfunctions.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-reassigned-05719", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 2 mg / kg in combination.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04911", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Two mouse lines selected for differential sensitivities to beta-carboline - induced seizures are also differentially sensitive to various pharmacological effects of other GABA (A) receptor ligands.", "completion": "{\"entities\": [{\"text\": \"beta-carboline\", \"type\": \"Chemical\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}, {\"text\": \"GABA\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-05168", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The development of psychosis related to antiepileptic drug treatment is usually attributed to the interaction between the epileptic brain substratum and the antiepileptic drugs.", "completion": "{\"entities\": [{\"text\": \"psychosis\", \"type\": \"Disease\"}, {\"text\": \"epileptic\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03944", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Components of lemon essential oil attenuate dementia induced by scopolamine.", "completion": "{\"entities\": [{\"text\": \"dementia\", \"type\": \"Disease\"}, {\"text\": \"scopolamine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04341", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Immunohistochemistry displayed significantly increased expressions of MMP - 2, MMP - 9, ADAM - 10 and ADAM - 17 (all p < 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02648", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: One of the twins developed complete heart block and dilated cardiomyopathy related to lopinavir/ritonavir therapy, a boosted protease - inhibitor agent, while the other twin developed mild bradycardia.", "completion": "{\"entities\": [{\"text\": \"heart block\", \"type\": \"Disease\"}, {\"text\": \"dilated cardiomyopathy\", \"type\": \"Disease\"}, {\"text\": \"lopinavir/ritonavir\", \"type\": \"Chemical\"}, {\"text\": \"bradycardia\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04580", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The BALB / C mouse was the most sensitive strain and could serve as the strain of choice for evaluating the side effects of amantadine.", "completion": "{\"entities\": [{\"text\": \"amantadine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03235", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The influence of sevoflurane on lidocaine - induced convulsions was studied in cats.", "completion": "{\"entities\": [{\"text\": \"sevoflurane\", \"type\": \"Chemical\"}, {\"text\": \"lidocaine\", \"type\": \"Chemical\"}, {\"text\": \"convulsions\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-05207", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: All but one of the patients were over 60 years old, and the 6 who died were all older than 65.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01146", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Number and total anionic site surface in the remaining part of the glomerular basement membrane (lamina densa and lamina rara interna) were not significantly changed.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02989", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: MEASUREMENTS AND MAIN RESULTS: of 23 patients who received docetaxel alone developed VTE, whereas 9 of 47 patients (19 %) who received docetaxel plus thalidomide developed VTE (p = 0.", "completion": "{\"entities\": [{\"text\": \"docetaxel\", \"type\": \"Chemical\"}, {\"text\": \"VTE\", \"type\": \"Disease\"}, {\"text\": \"thalidomide\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04102", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Both incidents occurred within a year.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03113", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Possible risk factors for the development of hepatotoxicity in patients treated with therapeutic doses of paracetamol are discussed.", "completion": "{\"entities\": [{\"text\": \"hepatotoxicity\", \"type\": \"Disease\"}, {\"text\": \"paracetamol\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04742", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Analysis was performed on 61 women with chemotherapy - responsive metastatic breast cancer receiving 96 - h infusional cyclophosphamide as part of a triple sequential high - dose regimen to assess association between presence of peritransplant congestive heart failure (CHF) and the following pretreatment characteristics: presence of electrocardiogram (EKG) abnormalities, age, hypertension, prior cardiac history, smoking, diabetes mellitus, prior use of anthracyclines, and left - sided chest irradiation.", "completion": "{\"entities\": [{\"text\": \"breast cancer\", \"type\": \"Disease\"}, {\"text\": \"cyclophosphamide\", \"type\": \"Chemical\"}, {\"text\": \"congestive heart failure\", \"type\": \"Disease\"}, {\"text\": \"CHF\", \"type\": \"Disease\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}, {\"text\": \"diabetes mellitus\", \"type\": \"Disease\"}, {\"text\": \"anthracyclines\", \"type\": \"Chemical\"}]}", "n_entities": 7}
{"ref": "bc5cdr-train-02429", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Interaction between warfarin and levofloxacin: case series.", "completion": "{\"entities\": [{\"text\": \"warfarin\", \"type\": \"Chemical\"}, {\"text\": \"levofloxacin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01413", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We describe a patient who developed dilated cardiomyopathy and clinical congestive heart failure after 2 months of therapy with amphotericin B (AmB) for disseminated coccidioidomycosis.", "completion": "{\"entities\": [{\"text\": \"dilated cardiomyopathy\", \"type\": \"Disease\"}, {\"text\": \"heart failure\", \"type\": \"Disease\"}, {\"text\": \"amphotericin B\", \"type\": \"Chemical\"}, {\"text\": \"AmB\", \"type\": \"Chemical\"}, {\"text\": \"coccidioidomycosis\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-01838", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The leading causes of death were pneumonia and bronchitis (44.", "completion": "{\"entities\": [{\"text\": \"death\", \"type\": \"Disease\"}, {\"text\": \"pneumonia\", \"type\": \"Disease\"}, {\"text\": \"bronchitis\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03607", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Previous research in this laboratory has shown that a diet of intermittent excessive sugar consumption produces a state with neurochemical and behavioral similarities to drug dependency.", "completion": "{\"entities\": [{\"text\": \"drug dependency\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04057", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Although preclinical and clinical findings suggest pulsatile stimulation of striatal postsynaptic receptors as a key mechanism underlying levodopa - induced dyskinesias, their pathogenesis is still unclear.", "completion": "{\"entities\": [{\"text\": \"levodopa\", \"type\": \"Chemical\"}, {\"text\": \"dyskinesias\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05220", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: From such experiments there is evidence that characterization and detection of apomorphine - induced activity in rodents critically depends upon the test conditions employed.", "completion": "{\"entities\": [{\"text\": \"apomorphine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02402", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 4 %, respectively (P = 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00053", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The results of this pilot study suggest that fusidic acid may be of benefit in selected chronic active Crohn's disease patients in whom conventional treatment is ineffective.", "completion": "{\"entities\": [{\"text\": \"fusidic acid\", \"type\": \"Chemical\"}, {\"text\": \"Crohn's disease\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01666", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Its activity is believed to be due modulation of the tumour milieu, including downregulation of angiogenesis and inflammatory cytokines.", "completion": "{\"entities\": [{\"text\": \"tumour\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03208", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Fatal intracranial bleeding associated with prehospital use of epinephrine.", "completion": "{\"entities\": [{\"text\": \"intracranial bleeding\", \"type\": \"Disease\"}, {\"text\": \"epinephrine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00952", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Three patients who had experienced neuroleptic - induced akathisia in the past reported that the symptoms of fluoxetine - induced akathisia were identical, although somewhat milder.", "completion": "{\"entities\": [{\"text\": \"akathisia\", \"type\": \"Disease\"}, {\"text\": \"fluoxetine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04164", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Prilocaine is an amide local anesthetic with a duration of action similar to that of lidocaine.", "completion": "{\"entities\": [{\"text\": \"Prilocaine\", \"type\": \"Chemical\"}, {\"text\": \"lidocaine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02121", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: TAM induces hemolysis of erythrocytes as a function of concentration.", "completion": "{\"entities\": [{\"text\": \"TAM\", \"type\": \"Chemical\"}, {\"text\": \"hemolysis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02345", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The EEG shows characteristic triphasic waves in most patients with this complication.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-reassigned-04309", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 %) patients during treatment.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01421", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Such organophosphorus (OP) compounds as diisopropylfluorophosphate (DFP ), sarin and soman are potent inhibitors of acetylcholinesterases (AChEs) and butyrylcholinesterases (BChEs ). The acute toxicity of OPs is the result of their irreversible binding with AChEs in the central nervous system (CNS ), which elevates acetylcholine (ACh) levels.", "completion": "{\"entities\": [{\"text\": \"organophosphorus\", \"type\": \"Chemical\"}, {\"text\": \"OP\", \"type\": \"Chemical\"}, {\"text\": \"diisopropylfluorophosphate\", \"type\": \"Chemical\"}, {\"text\": \"DFP\", \"type\": \"Chemical\"}, {\"text\": \"sarin\", \"type\": \"Chemical\"}, {\"text\": \"soman\", \"type\": \"Chemical\"}, {\"text\": \"acetylcholine\", \"type\": \"Chemical\"}, {\"text\": \"ACh\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}, {\"text\": \"OPs\", \"type\": \"Chemical\"}]}", "n_entities": 10}
{"ref": "bc5cdr-train-02549", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The complete disappearance of BAEP waveforms with a consistent temporal delay suggests a possible adverse effect on the proximal eighth nerve.", "completion": "{\"entities\": [{\"text\": \"adverse effect on the proximal eighth nerve\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04518", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Diffusion - weighted imaging may be useful in predicting the outcomes of the lesions of tacrolimus - induced neurotoxicity", "completion": "{\"entities\": [{\"text\": \"tacrolimus\", \"type\": \"Chemical\"}, {\"text\": \"neurotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01641", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Norepinephrine signaling through beta - adrenergic receptors is critical for expression of cocaine - induced anxiety.", "completion": "{\"entities\": [{\"text\": \"Norepinephrine\", \"type\": \"Chemical\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"anxiety\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03072", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Verapamil withdrawal as a possible cause of myocardial infarction in a hypertensive woman with a normal coronary angiogram.", "completion": "{\"entities\": [{\"text\": \"Verapamil\", \"type\": \"Chemical\"}, {\"text\": \"myocardial infarction\", \"type\": \"Disease\"}, {\"text\": \"hypertensive\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00337", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Rats were treated with a single IV injection of puromycin aminonucleoside ,(PAN, 7.", "completion": "{\"entities\": [{\"text\": \"puromycin aminonucleoside\", \"type\": \"Chemical\"}, {\"text\": \"PAN\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03485", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Sodium status influences chronic amphotericin B nephrotoxicity in rats.", "completion": "{\"entities\": [{\"text\": \"Sodium\", \"type\": \"Chemical\"}, {\"text\": \"amphotericin B\", \"type\": \"Chemical\"}, {\"text\": \"nephrotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04029", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Hepatic reactions associated with ketoconazole in the United Kingdom.", "completion": "{\"entities\": [{\"text\": \"ketoconazole\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00769", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We also assessed cell viability, mitochondrial membrane potential changes and counted autophagic vacuoles in cultured cardiomyocytes.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04011", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The morphological changes presented a similar pattern.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00798", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The patient required massive transfusion support (55 units of red blood cells, 42 units of fresh - frozen plasma, 40 units of cryoprecipitate, 40 units of platelets, and three doses of recombinant Factor VIIa) for severe intraoperative and postoperative bleeding.", "completion": "{\"entities\": [{\"text\": \"intraoperative and postoperative bleeding\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00214", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A patient with sinuatrial disease and implanted pacemaker was treated with amiodarone (maximum dose 1000 mg, maintenance dose 800 mg daily) for 10 months, for control of supraventricular tachyarrhythmias.", "completion": "{\"entities\": [{\"text\": \"sinuatrial disease\", \"type\": \"Disease\"}, {\"text\": \"amiodarone\", \"type\": \"Chemical\"}, {\"text\": \"supraventricular tachyarrhythmias\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02623", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05 ); using mixed model for repeated measures (MMRM ), changes at day 42 were significantly greater with asenapine at 5 and 10 mg BID (- 21.", "completion": "{\"entities\": [{\"text\": \"asenapine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02027", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It is therefore very important to follow the changes of gallbladder function during long - term octreotide therapy of acromegalic", "completion": "{\"entities\": [{\"text\": \"octreotide\", \"type\": \"Chemical\"}, {\"text\": \"acromegalic\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01134", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A minority of anionic sites were scattered throughout the lamina densa and lamina rara interna, and were significantly smaller than those in the lamina rara externa of the glomerular basement membrane (p < 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01325", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Seventy - three percent (73 / 99) of the study participants were treated for headache and 70 %(70 / 99) for nausea.", "completion": "{\"entities\": [{\"text\": \"headache\", \"type\": \"Disease\"}, {\"text\": \"nausea\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04136", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 2% compared with 54.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01265", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In 2 of the 3 cases the patients were also taking lithium carbonate and beta - blockers, both of which could have contributed to the incontinence.", "completion": "{\"entities\": [{\"text\": \"lithium carbonate\", \"type\": \"Chemical\"}, {\"text\": \"incontinence\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01153", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0228) in the plasma creatinine concentration and a significant (p = 0.", "completion": "{\"entities\": [{\"text\": \"creatinine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03091", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The interpeduncular nucleus regulates nicotine' s effects on free - field activity.", "completion": "{\"entities\": [{\"text\": \"nicotine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02845", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Capsaicin injection reliably induced a dose - dependent flare (p < 0.", "completion": "{\"entities\": [{\"text\": \"Capsaicin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02528", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 006, respectively) in the pergolide group.", "completion": "{\"entities\": [{\"text\": \"pergolide\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00975", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The systolic pressure variation (SPV ), which is the difference between the maximal and minimal values of the systolic blood pressure (SBP) after one positive - pressure breath, was studied in ventilated dogs subjected to hypotension.", "completion": "{\"entities\": [{\"text\": \"hypotension\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04484", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 9 ). Treatment duration longer than 1 year was associated with an eightfold increased risk (OR = 7.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04044", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In two of the three deaths probably associated with ketoconazole treatment the drug had been continued after the onset of jaundice and other symptoms of hepatitis.", "completion": "{\"entities\": [{\"text\": \"deaths\", \"type\": \"Disease\"}, {\"text\": \"ketoconazole\", \"type\": \"Chemical\"}, {\"text\": \"jaundice\", \"type\": \"Disease\"}, {\"text\": \"hepatitis\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01821", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Mazindol doses not slow the progression of weakness in Duchenne dystrophy", "completion": "{\"entities\": [{\"text\": \"Mazindol\", \"type\": \"Chemical\"}, {\"text\": \"weakness\", \"type\": \"Disease\"}, {\"text\": \"Duchenne dystrophy\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02567", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Urinary sodium excretion reached signficantly lower values in sgk1 (+/+) mice (15 +/- 5 mumol / mg crea) than in sgk1 (-/-) mice (35 +/- 5 mumol / mg crea) and was associated with a significantly higher body weight gain in sgk1 (+/+) compared with sgk1 (-/-) mice (+ 6.", "completion": "{\"entities\": [{\"text\": \"sodium\", \"type\": \"Chemical\"}, {\"text\": \"weight gain\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01610", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSION: In utero, exposure to tobacco smoking seems to have a small impact on outer hair cells.", "completion": "{\"entities\": [{\"text\": \"smoking\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01903", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: With mild toxicity, a reduction to 30 or 40 mg / kg per dose should result in a reversal of the abnormal results to normal within four weeks.", "completion": "{\"entities\": [{\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03951", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Initial testing in a time - dependent forgetting task employing a 24 - h delay between training and testing showed that metrifonate improved object recognition (at 10 and 30 mg / kg, p.", "completion": "{\"entities\": [{\"text\": \"metrifonate\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02199", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This case report highlights the fact that the angiotensin II receptor antagonist losartan can cause serious unexpected complications in patients with renovascular disease", "completion": "{\"entities\": [{\"text\": \"angiotensin II\", \"type\": \"Chemical\"}, {\"text\": \"losartan\", \"type\": \"Chemical\"}, {\"text\": \"renovascular disease\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04879", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The most common adverse events were nausea (17.", "completion": "{\"entities\": [{\"text\": \"nausea\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00916", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: OBJECTIVE: This study was designed to determine whether patients maintained on a regimen of lithium on a once - per - day schedule have lower urine volumes than do patients receiving multiple doses per day.", "completion": "{\"entities\": [{\"text\": \"lithium\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00636", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The events are consistent with a severe reaction to calcium chelation by sodium citrate anticoagulant resulting in symptomatic systemic hypocalcemia.", "completion": "{\"entities\": [{\"text\": \"calcium\", \"type\": \"Chemical\"}, {\"text\": \"sodium citrate\", \"type\": \"Chemical\"}, {\"text\": \"hypocalcemia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03665", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 1 ), atrial septal defects (AOR = 1.", "completion": "{\"entities\": [{\"text\": \"atrial septal defects\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03920", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Early trials of cisplatin and amifostine also suggested that the incidence and severity of cisplatin - induced nephrotoxicity, ototoxicity, and neuropathy were reduced.", "completion": "{\"entities\": [{\"text\": \"cisplatin\", \"type\": \"Chemical\"}, {\"text\": \"amifostine\", \"type\": \"Chemical\"}, {\"text\": \"nephrotoxicity\", \"type\": \"Disease\"}, {\"text\": \"ototoxicity\", \"type\": \"Disease\"}, {\"text\": \"neuropathy\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-00834", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Outcome improvement with more intensive chemotherapy has significantly increased the incidence and severity of adverse events.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00021", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The times to first fasciculation, twitch suppression and tetanus suppression were inversely related to the infusion rates.", "completion": "{\"entities\": [{\"text\": \"fasciculation\", \"type\": \"Disease\"}, {\"text\": \"twitch\", \"type\": \"Disease\"}, {\"text\": \"tetanus\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00353", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A 72 - year - old woman was admitted to the hospital with\" flash\" pulmonary edema, preceded by chest pain, requiring intubation.", "completion": "{\"entities\": [{\"text\": \"pulmonary edema\", \"type\": \"Disease\"}, {\"text\": \"chest pain\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04670", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 001 ). More patients were (completely, very or somewhat) satisfied 2 h after treatment with rizatriptan (69.", "completion": "{\"entities\": [{\"text\": \"rizatriptan\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00035", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: HP failed to accentuante progression of renal failure and in fact tended to increase GFR and decrease plasma creatinine levels in lithium pretreated rats.", "completion": "{\"entities\": [{\"text\": \"renal failure\", \"type\": \"Disease\"}, {\"text\": \"creatinine\", \"type\": \"Chemical\"}, {\"text\": \"lithium\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00294", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Provocation of postural hypotension by nitroglycerin in diabetic autonomic neuropathy ? The effect of nitroglycerin on heart rate and systolic blood pressure was compared in 5 normal subjects, 12 diabetic subjects without autonomic neuropathy, and 5 diabetic subjects with autonomic neuropathy.", "completion": "{\"entities\": [{\"text\": \"hypotension\", \"type\": \"Disease\"}, {\"text\": \"nitroglycerin\", \"type\": \"Chemical\"}, {\"text\": \"diabetic\", \"type\": \"Disease\"}, {\"text\": \"diabetic autonomic neuropathy\", \"type\": \"Disease\"}, {\"text\": \"autonomic neuropathy\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-03584", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Isolated myelopathy or peripheral neuropathy, or these manifestations occurring together, were infrequent.", "completion": "{\"entities\": [{\"text\": \"myelopathy\", \"type\": \"Disease\"}, {\"text\": \"peripheral neuropathy\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00238", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: There was pain on i.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04786", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We found no correlation of angiogenesis soluble markers with either hemoglobin or haptoglobin.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03307", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In phase A, extrapyramidal signs tended to be greater with the standard dose than in the other two conditions, primarily because of a subgroup (20 %) who developed moderate to severe signs.", "completion": "{\"entities\": [{\"text\": \"extrapyramidal signs\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04735", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: Results of these studies suggest that B1 and B2 receptors are engaged in transmission of nociceptive stimuli in both diabetic and toxic neuropathy.", "completion": "{\"entities\": [{\"text\": \"diabetic and toxic neuropathy\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01672", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 4 %). Eleven patients progressed during therapy.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00911", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: There was no evidence of repair to the damaged medullary interstitial matrix, or proliferation of remaining undamaged type 1 medullary interstitial cells after the recovery period following analgesic treatment.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02191", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We report the case of a 70 - year - old hypertensive man with a solitary kidney and chronic renal insufficiency who developed two episodes of transient anuria after losartan administration.", "completion": "{\"entities\": [{\"text\": \"hypertensive\", \"type\": \"Disease\"}, {\"text\": \"chronic renal insufficiency\", \"type\": \"Disease\"}, {\"text\": \"anuria\", \"type\": \"Disease\"}, {\"text\": \"losartan\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00363", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, coniine has failed to produce arthrogryposis in rats or mice and is only weakly teratogenic in rabbits.", "completion": "{\"entities\": [{\"text\": \"coniine\", \"type\": \"Chemical\"}, {\"text\": \"arthrogryposis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04652", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Of patients expressing a preference (89.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04462", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Five cases of thrombotic microangiopathy were found.", "completion": "{\"entities\": [{\"text\": \"thrombotic microangiopathy\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04380", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These differences were not observed during puberty.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03445", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Overall, 21 out of 104 patients (20.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02881", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The purpose of this report is to describe two cases of a disulfiram - like syndrome following occupational exposure to hydrogen cyanamide.", "completion": "{\"entities\": [{\"text\": \"disulfiram\", \"type\": \"Chemical\"}, {\"text\": \"hydrogen cyanamide\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03747", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: He complained of pain and visual disturbance in the ipsilateral eye 30 h after the injection.", "completion": "{\"entities\": [{\"text\": \"pain and visual disturbance in the ipsilateral eye\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00654", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Biopsies performed in five patients revealed new pathological changes: One membranoproliferative glomerulopathy and interstitial nephritis.", "completion": "{\"entities\": [{\"text\": \"membranoproliferative glomerulopathy\", \"type\": \"Disease\"}, {\"text\": \"interstitial nephritis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02612", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The effect of modafinil interacted with the abstinence week and was associated with longer total sleep time and shorter REM sleep latency in the third week of abstinence.", "completion": "{\"entities\": [{\"text\": \"modafinil\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03323", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: As anticipated, adriamycin elicited nephrotic range proteinuria, renal interstitial damage and mild focal glomerulosclerosis.", "completion": "{\"entities\": [{\"text\": \"adriamycin\", \"type\": \"Chemical\"}, {\"text\": \"nephrotic\", \"type\": \"Disease\"}, {\"text\": \"proteinuria\", \"type\": \"Disease\"}, {\"text\": \"renal interstitial damage\", \"type\": \"Disease\"}, {\"text\": \"focal glomerulosclerosis\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-01229", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The current work indicates the ability of PG-9 to induce beneficial effects on cognitive processes and stimulate activity of NGF synthesis in astroglial cells.", "completion": "{\"entities\": [{\"text\": \"PG-9\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-reassigned-02151", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In a patient receiving phenytoin", "completion": "{\"entities\": [{\"text\": \"phenytoin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03232", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, the concomitant occurrence of HBeAg negativity (PC / BCP ), sP120T, and LAM resistance resulted in the restoration of replication to levels of wild - type HBV.", "completion": "{\"entities\": [{\"text\": \"HBeAg\", \"type\": \"Chemical\"}, {\"text\": \"LAM\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00694", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After adjustment for these variables as confounders, use of BZDs / RDs was not associated with cognitive function as measured by the MMSE.", "completion": "{\"entities\": [{\"text\": \"BZDs\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00552", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CASE SUMMARIES: Two patients developed prolonged cholestatic hepatitis after receiving ticlopidine following percutaneous coronary angioplasty, with complete remission during the follow - up period.", "completion": "{\"entities\": [{\"text\": \"cholestatic hepatitis\", \"type\": \"Disease\"}, {\"text\": \"ticlopidine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01979", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: At this point it was assumed that the cytochrome P450 / CCl4 toxic state was both maximal and stable.", "completion": "{\"entities\": [{\"text\": \"CCl4\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04430", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: No such obvious upregulation of Pgp was observed in liver sections.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01149", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The nephrotoxic action of anticancer drugs such as nitrogranulogen (NG ), methotrexate (MTX ), 5-fluorouracil (5-FU) and cyclophosphamide (CY) administered alone or in combination [MTX + 5-FU + CY (CMF )] was evaluated in experiments on Wistar rats.", "completion": "{\"entities\": [{\"text\": \"nephrotoxic\", \"type\": \"Disease\"}, {\"text\": \"nitrogranulogen\", \"type\": \"Chemical\"}, {\"text\": \"NG\", \"type\": \"Chemical\"}, {\"text\": \"methotrexate\", \"type\": \"Chemical\"}, {\"text\": \"MTX\", \"type\": \"Chemical\"}, {\"text\": \"5-fluorouracil\", \"type\": \"Chemical\"}, {\"text\": \"5-FU\", \"type\": \"Chemical\"}, {\"text\": \"cyclophosphamide\", \"type\": \"Chemical\"}, {\"text\": \"CY\", \"type\": \"Chemical\"}]}", "n_entities": 9}
{"ref": "bc5cdr-train-04367", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In contrast to the systemic renin - angiotensin system, which is suppressed in response to HS in male DS, intrarenal angiotensinogen expression is increased, and intrarenal levels of ANG II are not suppressed.", "completion": "{\"entities\": [{\"text\": \"angiotensin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00489", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Sex, age, diagnosis (bipolar I vs.", "completion": "{\"entities\": [{\"text\": \"bipolar I\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00795", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These ecstasy - specific effects may be related to the vulnerability of isocortical and allocortical regions to the neurotoxic effects of ecstasy", "completion": "{\"entities\": [{\"text\": \"ecstasy\", \"type\": \"Chemical\"}, {\"text\": \"neurotoxic\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02023", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In all of 7 patients examined acutely, gallbladder contractility was inhibited after a single 100 - micrograms injection.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-reassigned-02026", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This was significantly different (P less than 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01287", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In behavioral studies, pre - treatment of mice with BD1018, BD1063, or LR132 significantly attenuated cocaine - induced convulsions and lethality.", "completion": "{\"entities\": [{\"text\": \"BD1018\", \"type\": \"Chemical\"}, {\"text\": \"BD1063\", \"type\": \"Chemical\"}, {\"text\": \"LR132\", \"type\": \"Chemical\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"convulsions\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-04764", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After she discontinued the omeprazole, her hemoglobin and hematocrit gradually returned to normal.", "completion": "{\"entities\": [{\"text\": \"omeprazole\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00984", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 02 ). The delta down, which is the measure of decrease of SBP after a mechanical breath, was 20.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04384", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: No statistically significant changes in behavior or receptor binding were found in PD males with the exception of increased (3) H - MK-801 binding in cortex.", "completion": "{\"entities\": [{\"text\": \"H\", \"type\": \"Chemical\"}, {\"text\": \"MK-801\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02646", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Twin preterm neonates with cardiac toxicity related to lopinavir/ritonavir therapy.", "completion": "{\"entities\": [{\"text\": \"cardiac toxicity\", \"type\": \"Disease\"}, {\"text\": \"lopinavir/ritonavir\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00645", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Mean follow - up on SRL therapy was 20 +/- 12 (6 to 43) months.", "completion": "{\"entities\": [{\"text\": \"SRL\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01876", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 3 mmHg ). These variables returned to baseline when rigidity was abolished with metocurine.", "completion": "{\"entities\": [{\"text\": \"rigidity\", \"type\": \"Disease\"}, {\"text\": \"metocurine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02849", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 001 ), regardless of whether first - time ratings were requested immediately, after one hour or after one day.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01798", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Therefore, certain limitations for malaria prophylaxis and treatment with mefloquine", "completion": "{\"entities\": [{\"text\": \"malaria\", \"type\": \"Disease\"}, {\"text\": \"mefloquine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01025", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the twin pregnancy, the mother had Crohn's disease.", "completion": "{\"entities\": [{\"text\": \"Crohn's disease\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01292", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Together, the data suggests that functional antagonism of sigma receptors is capable of attenuating a number of cocaine", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03410", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In order that this syndrome might be investigated changes in mental status (M.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02005", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The results suggest a possible involvement of the renin - angiotensin system in the development of puromycin aminonucleoside - induced nephrosis", "completion": "{\"entities\": [{\"text\": \"angiotensin\", \"type\": \"Chemical\"}, {\"text\": \"puromycin aminonucleoside\", \"type\": \"Chemical\"}, {\"text\": \"nephrosis\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01418", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Numerous anecdotal reports suggest that products containing quinine may produce neurological complications, including confusion, altered mental status, seizures, and coma, particularly in older women.", "completion": "{\"entities\": [{\"text\": \"quinine\", \"type\": \"Chemical\"}, {\"text\": \"neurological complications\", \"type\": \"Disease\"}, {\"text\": \"confusion\", \"type\": \"Disease\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}, {\"text\": \"coma\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-00307", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Beyond 8 days of DES exposure, the immunochemically PRL - positive proportion of cells increased to over 50% of the total population.", "completion": "{\"entities\": [{\"text\": \"DES\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01704", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In contrast, SSR103800 failed to affect hyperactivity induced by amphetamine or naturally observed in dopamine transporter (DAT (-/-)) knockout mice (10 - 30 mg / kg p.", "completion": "{\"entities\": [{\"text\": \"SSR103800\", \"type\": \"Chemical\"}, {\"text\": \"hyperactivity\", \"type\": \"Disease\"}, {\"text\": \"amphetamine\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00779", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: Using the French Pharmacovigilance database, we selected the cases of confusion reported since 1985 with valproic acid.", "completion": "{\"entities\": [{\"text\": \"confusion\", \"type\": \"Disease\"}, {\"text\": \"valproic acid\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05137", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The electrophysiological recording in vitro showed that Rg1 restored the LTP in slices from the rats treated with morphine, but not changed LTP in the slices from normal saline - or morphine / Rg1 - treated rats; this restoration could be inhibited by N-methyl-D-aspartate (NMDA) receptor antagonist MK801.", "completion": "{\"entities\": [{\"text\": \"Rg1\", \"type\": \"Chemical\"}, {\"text\": \"morphine\", \"type\": \"Chemical\"}, {\"text\": \"N-methyl-D-aspartate\", \"type\": \"Chemical\"}, {\"text\": \"NMDA\", \"type\": \"Chemical\"}, {\"text\": \"MK801\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-02487", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: o .) in the rat haloperidol - induced catalepsy model for Parkinson's disease", "completion": "{\"entities\": [{\"text\": \"haloperidol\", \"type\": \"Chemical\"}, {\"text\": \"catalepsy\", \"type\": \"Disease\"}, {\"text\": \"Parkinson's disease\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04811", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 2 that might be responsible for the antinociception and the anti - amnesic effect induced by (+/-)- PG-9 through an increase in acetylcholine extracellular levels.", "completion": "{\"entities\": [{\"text\": \"amnesic\", \"type\": \"Disease\"}, {\"text\": \"PG-9\", \"type\": \"Chemical\"}, {\"text\": \"acetylcholine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01517", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Her QT interval returned to normal upon withdrawal of ketoconazole.", "completion": "{\"entities\": [{\"text\": \"ketoconazole\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01860", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Application of a delayed feedback signal, in the form of a 2 - h systemic corticosterone infusion in urethane - anesthetized rats with pharmacological blockade of glucocorticoid synthesis, is without effect on the resting secretion of arginine vasopressin and oxytocin at any corticosterone feedback dose tested.", "completion": "{\"entities\": [{\"text\": \"corticosterone\", \"type\": \"Chemical\"}, {\"text\": \"urethane\", \"type\": \"Chemical\"}, {\"text\": \"arginine vasopressin\", \"type\": \"Chemical\"}, {\"text\": \"oxytocin\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03258", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Apamin (10 ng) had a tendency to decrease the convulsive threshold (21.", "completion": "{\"entities\": [{\"text\": \"Apamin\", \"type\": \"Chemical\"}, {\"text\": \"convulsive\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04934", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Ketamine can improve morphine analgesia in difficult pain syndromes, such as neuropathic pain.", "completion": "{\"entities\": [{\"text\": \"Ketamine\", \"type\": \"Chemical\"}, {\"text\": \"morphine\", \"type\": \"Chemical\"}, {\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"neuropathic pain\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04247", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Several recent studies have stressed the renal sparing features of sulindac, owing to its lack of interference with renal prostacyclin synthesis.", "completion": "{\"entities\": [{\"text\": \"sulindac\", \"type\": \"Chemical\"}, {\"text\": \"prostacyclin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01305", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 9 nM) closely correlate with the free concentration in man causing QT effects.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04864", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: OBJECTIVE: The objective of this study was to compare the safety profiles of the 4 - mg nicotine lozenge and 4 - mg nicotine gum in smokers with selected label - restricted diseases.", "completion": "{\"entities\": [{\"text\": \"nicotine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03559", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Although there was a discrepancy between the amount of cTnI and cTnT after DOX, probably due to heterogeneity in cross - reactivities of mAbs to various cTnI and cTnT forms, it is likely that cTnT in rats after DOX indicates cell damage determined by the magnitude of injury induced and that cTnT should be a useful marker for the prediction of experimentally induced cardiotoxicity", "completion": "{\"entities\": [{\"text\": \"DOX\", \"type\": \"Chemical\"}, {\"text\": \"cardiotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03924", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Intravenous hydration and mannitol was administered before and after cisplatin.", "completion": "{\"entities\": [{\"text\": \"mannitol\", \"type\": \"Chemical\"}, {\"text\": \"cisplatin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-03177", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It is suggested that nefiracetam", "completion": "{\"entities\": [{\"text\": \"nefiracetam\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04838", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The increase in free radical generation has been implicated as one of the important mechanisms of cognitive impairment by antiepileptic drugs.", "completion": "{\"entities\": [{\"text\": \"cognitive impairment\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00632", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Reported medications included bumetanide, pravastatin, and paroxetine.", "completion": "{\"entities\": [{\"text\": \"bumetanide\", \"type\": \"Chemical\"}, {\"text\": \"pravastatin\", \"type\": \"Chemical\"}, {\"text\": \"paroxetine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03358", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pharmacokinetics of desipramine HCl when administered with cinacalcet HCl.", "completion": "{\"entities\": [{\"text\": \"desipramine HCl\", \"type\": \"Chemical\"}, {\"text\": \"cinacalcet HCl\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03845", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Alpha and beta coma in drug intoxication uncomplicated by cerebral hypoxia.", "completion": "{\"entities\": [{\"text\": \"coma\", \"type\": \"Disease\"}, {\"text\": \"cerebral hypoxia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03060", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: To test the validity of the hypothesis that hypomethylation of DNA plays an important role in the initiation of carcinogenic process, 5-azacytidine (5-AzC )(10 mg / kg ), an inhibitor of DNA methylation, was given to rats during the phase of repair synthesis induced by the three carcinogens, benzo[a]-pyrene (200 mg / kg ), N-methyl-N-nitrosourea (60 mg / kg) and 1,2-dimethylhydrazine (1,2-DMH )(100 mg / kg ). The initiated hepatocytes in the liver were assayed as the gamma - glutamyltransferase (gamma - GT) positive foci formed following a 2 - week selection regimen consisting of dietary 0.", "completion": "{\"entities\": [{\"text\": \"initiation of carcinogenic process\", \"type\": \"Disease\"}, {\"text\": \"5-azacytidine\", \"type\": \"Chemical\"}, {\"text\": \"5-AzC\", \"type\": \"Chemical\"}, {\"text\": \"benzo[a]-pyrene\", \"type\": \"Chemical\"}, {\"text\": \"N-methyl-N-nitrosourea\", \"type\": \"Chemical\"}, {\"text\": \"1,2-dimethylhydrazine\", \"type\": \"Chemical\"}, {\"text\": \"1,2-DMH\", \"type\": \"Chemical\"}]}", "n_entities": 7}
{"ref": "bc5cdr-train-02906", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cardiac toxicity is a major complication which limits the use of adriamycin as a chemotherapeutic agent.", "completion": "{\"entities\": [{\"text\": \"Cardiac toxicity\", \"type\": \"Disease\"}, {\"text\": \"adriamycin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04854", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Treatment with 150 mg / kg PDTC before and following status epilepticus significantly increased the mortality rate to 100 %. Administration of 50 mg / kg PDTC (low - dose) did not exert major effects on the development of a status epilepticus or the mortality rate.", "completion": "{\"entities\": [{\"text\": \"PDTC\", \"type\": \"Chemical\"}, {\"text\": \"status epilepticus\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01922", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Treatment of psoriasis with azathioprine.", "completion": "{\"entities\": [{\"text\": \"psoriasis\", \"type\": \"Disease\"}, {\"text\": \"azathioprine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01234", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A case of recurarization in the recovery room is reported.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04863", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The increased nicotine exposure from the lozenge has raised questions about the relative safety of the lozenge and gum.", "completion": "{\"entities\": [{\"text\": \"nicotine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-reassigned-03816", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The WHO reported 82 cases.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03786", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: All three cytopenias were completely reversible following cessation of treatment; the time required for recovery of the erythron (approximately 1 month) was considerably longer than that of the granulocytes and platelets (hours to a few days ). Upon rechallenge with either cephalosporin, the hematologic syndrome was reproduced in most dogs tested; cefonicid (but not cefazedone )- treated dogs showed a substantially reduced induction period (15 +/- 5 days) compared to that of the first exposure to the drug (61 +/- 24 days ). This observation, along with the rapid rate of decline in red cell mass parameters of affected dogs, suggests that a hemolytic component complicated the red cell production problem and that multiple toxicologic mechanisms contributed to the cytopenia.", "completion": "{\"entities\": [{\"text\": \"cytopenia\", \"type\": \"Disease\"}, {\"text\": \"cytopenias\", \"type\": \"Disease\"}, {\"text\": \"cephalosporin\", \"type\": \"Chemical\"}, {\"text\": \"hematologic syndrome\", \"type\": \"Disease\"}, {\"text\": \"cefonicid\", \"type\": \"Chemical\"}, {\"text\": \"cefazedone\", \"type\": \"Chemical\"}, {\"text\": \"hemolytic\", \"type\": \"Disease\"}]}", "n_entities": 7}
{"ref": "bc5cdr-train-03496", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Initial brain magnetic resonance imaging (MRI) were obtained after the hospitalization, including DWI (8 / 8 ), apparent diffusion coefficient (ADC) map (4 / 8 ), FLAIR (7 / 8 ), and T2 - weighted image (8 / 8 ). Follow - up MRIs were performed on 5 patients from third to 14th days after discontinuation of metronidazole administration.", "completion": "{\"entities\": [{\"text\": \"metronidazole\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00064", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: During an 18 - month period of study 41 hemodialyzed patients receiving desferrioxamine (10 - 40 mg / kg BW / 3 times weekly) for the first time were monitored for detection of audiovisual toxicity.", "completion": "{\"entities\": [{\"text\": \"desferrioxamine\", \"type\": \"Chemical\"}, {\"text\": \"audiovisual toxicity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00843", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We also explore different dosing and schedules of capecitabine administration.", "completion": "{\"entities\": [{\"text\": \"capecitabine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03000", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The patient progressively developed petechiae and purpura on thorax and lower limbs.", "completion": "{\"entities\": [{\"text\": \"petechiae\", \"type\": \"Disease\"}, {\"text\": \"purpura\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05170", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This case suggests that the psychotic symptoms that occur following phenytoin treatment in some epileptic patients may be the direct result of medication, unrelated to seizures", "completion": "{\"entities\": [{\"text\": \"psychotic symptoms\", \"type\": \"Disease\"}, {\"text\": \"phenytoin\", \"type\": \"Chemical\"}, {\"text\": \"epileptic\", \"type\": \"Disease\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01331", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 2 %). The difference between the bolus and infusion groups in the percentage of participants who saw a 50% reduction in their headache intensity within 30 minutes was 11.", "completion": "{\"entities\": [{\"text\": \"headache\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03387", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These results suggest that paramethasone caused pseudoallergic reactions in our patients.", "completion": "{\"entities\": [{\"text\": \"paramethasone\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03554", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Analysis of data revealed a significant correlation between maximal cTnT and ED and ES LV diameters / BW (r = 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-reassigned-03044", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cocaine induced myocardial ischemia.", "completion": "{\"entities\": [{\"text\": \"Cocaine\", \"type\": \"Chemical\"}, {\"text\": \"myocardial ischemia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00910", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Renal structure and concentrating ability were examined after a recovery period of up to 18 weeks, when no analgesics were given, to investigate whether the analgesic - induced changes were reversible.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00571", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A significant up - regulation of alphaENaC and betaENaC mRNA abundance on days 1 and 2 preceded sodium retention on days 2 and 3.", "completion": "{\"entities\": [{\"text\": \"sodium\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00735", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: SETTING: Ophthalmology clinic of an academic hospital.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03728", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Urinary excretion of Pirarubicin in the first 24 hours was less than or equal to 10 %. Activity was noted in mesothelioma, leiomyosarcoma, and basal cell carcinoma", "completion": "{\"entities\": [{\"text\": \"Pirarubicin\", \"type\": \"Chemical\"}, {\"text\": \"mesothelioma\", \"type\": \"Disease\"}, {\"text\": \"leiomyosarcoma\", \"type\": \"Disease\"}, {\"text\": \"basal cell carcinoma\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04066", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: At hippocampal Schaeffer collateral - CA1 synapses, long - term potentiation was preserved in BMC - transplanted rats compared to epileptic controls.", "completion": "{\"entities\": [{\"text\": \"epileptic\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00573", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The amounts of alphaENaC, betaENaC and gammaENaC proteins were not increased during PAN - induced sodium retention.", "completion": "{\"entities\": [{\"text\": \"PAN\", \"type\": \"Chemical\"}, {\"text\": \"sodium\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02951", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The results indicate that the deprived area of A1 undergoes extensive reorganization and becomes responsive to intact cochlear frequencies.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04621", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 25; PC02 70 to 100 mm Hg: P02 20 to 40 mm Hg ), infusion of aminophylline resulted in an even greater decrease in ventricular fibrillation threshold to 60 percent of the control level.", "completion": "{\"entities\": [{\"text\": \"aminophylline\", \"type\": \"Chemical\"}, {\"text\": \"ventricular fibrillation\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03465", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Azidothymidine (AZT )- induced anemia in mice can be reversed by the administration of IGF - IL - 3 (fusion protein of insulin - like growth factor II (IGF II) and interleukin 3 ). Although interleukin 3 (IL - 3) and erythropoietin (EPO) are known to act synergistically on hematopoietic cell proliferation in vitro, injection of IGF - IL - 3 and EPO in AZT - treated mice resulted in a reduction of red cells and an increase of plasma EPO levels as compared to animals treated with IGF - IL - 3 or EPO alone.", "completion": "{\"entities\": [{\"text\": \"Azidothymidine\", \"type\": \"Chemical\"}, {\"text\": \"AZT\", \"type\": \"Chemical\"}, {\"text\": \"anemia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00589", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In contrast, serotonin release from platelets does not provoke migraine, it may even counteract the headache and the concomitant CGRP", "completion": "{\"entities\": [{\"text\": \"serotonin\", \"type\": \"Chemical\"}, {\"text\": \"migraine\", \"type\": \"Disease\"}, {\"text\": \"headache\", \"type\": \"Disease\"}, {\"text\": \"CGRP\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03146", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: At least one episode of grade 3 or 4 granulocytopenia was seen in 59% of patients.", "completion": "{\"entities\": [{\"text\": \"granulocytopenia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04041", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Allergic manifestations such as rash and eosinophilia were rare.", "completion": "{\"entities\": [{\"text\": \"rash\", \"type\": \"Disease\"}, {\"text\": \"eosinophilia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01535", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The extent of inhibition of brain cholinesterase activity evoked by DCE at the dose of 400 mg / kg was 22% in young and 19% in aged mice.", "completion": "{\"entities\": [{\"text\": \"DCE\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00838", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CNS complications included posterior reversible leukoencephalopathy syndrome (n = 10 ), stroke (n = 5 ), temporal lobe epilepsy (n = 2 ), high - dose methotrexate toxicity (n = 2 ), syndrome of inappropriate antidiuretic hormone secretion (n = 1 ), and other unclassified events (n = 7 ). In conclusion, CNS complications are frequent events during ALL", "completion": "{\"entities\": [{\"text\": \"leukoencephalopathy\", \"type\": \"Disease\"}, {\"text\": \"stroke\", \"type\": \"Disease\"}, {\"text\": \"temporal lobe epilepsy\", \"type\": \"Disease\"}, {\"text\": \"methotrexate\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}, {\"text\": \"inappropriate antidiuretic hormone secretion\", \"type\": \"Disease\"}, {\"text\": \"ALL\", \"type\": \"Disease\"}]}", "n_entities": 7}
{"ref": "bc5cdr-train-01503", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: Markers of fibrinolysis, thrombin - activatable fibrinolysis inhibitor (TAFI ), tissue - type plasminogen activator (tPA ), and plasminogen activator inhibitor - 1 (PAI - 1) levels were studied for the evaluation of short - term effects of raloxifene administration in postmenopausal women.", "completion": "{\"entities\": [{\"text\": \"raloxifene\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04595", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Dobutamine stress echocardiography: a sensitive indicator of diminished myocardial function in asymptomatic doxorubicin - treated long - term survivors of childhood cancer.", "completion": "{\"entities\": [{\"text\": \"Dobutamine\", \"type\": \"Chemical\"}, {\"text\": \"doxorubicin\", \"type\": \"Chemical\"}, {\"text\": \"cancer\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01151", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Histopathologic evaluation of the kidneys was also performed.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02920", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This literature review suggests that general practitioners should prescribe scabicides with increased caution for certain at - risk groups, and give adequate warnings regarding potential toxicity", "completion": "{\"entities\": [{\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01156", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Following polytherapy according to the CMF regimen, a statistically significant decrease (p = 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04141", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The development of ESRD decreases survival, particularly in those patients treated with dialysis only.", "completion": "{\"entities\": [{\"text\": \"ESRD\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02316", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 1 mm ), a vasoactive intestinal polypeptide (VIP) antagonist, onto the exposed dura mater.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03790", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The administration of pharmacologic doses of pyridoxine hydrochloride led to a disappearance of symptoms.", "completion": "{\"entities\": [{\"text\": \"pyridoxine hydrochloride\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04031", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: By November 1984 the Committee on Safety of Medicines had received 82 reports of possible hepatotoxicity associated with the drug, including five deaths.", "completion": "{\"entities\": [{\"text\": \"hepatotoxicity\", \"type\": \"Disease\"}, {\"text\": \"deaths\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01581", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Statins can cause a necrotizing myopathy and hyperCKaemia which is reversible on cessation of the drug.", "completion": "{\"entities\": [{\"text\": \"Statins\", \"type\": \"Chemical\"}, {\"text\": \"myopathy\", \"type\": \"Disease\"}, {\"text\": \"hyperCKaemia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00249", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Large parenteral doses of vitamin D3 (15 to 17.", "completion": "{\"entities\": [{\"text\": \"vitamin D3\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02190", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Repeated transient anuria following losartan administration in a patient with a solitary kidney.", "completion": "{\"entities\": [{\"text\": \"anuria\", \"type\": \"Disease\"}, {\"text\": \"losartan\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01895", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Visual and auditory neurotoxicity was previously documented in 42 of 89 patients with transfusion - dependent anemia who were receiving iron chelation therapy with daily subcutaneous deferoxamine.", "completion": "{\"entities\": [{\"text\": \"Visual and auditory neurotoxicity\", \"type\": \"Disease\"}, {\"text\": \"anemia\", \"type\": \"Disease\"}, {\"text\": \"iron\", \"type\": \"Chemical\"}, {\"text\": \"deferoxamine\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02865", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Capsaicin (10 micro g) was injected into the masseter muscle to induce pain in 11 healthy volunteers.", "completion": "{\"entities\": [{\"text\": \"Capsaicin\", \"type\": \"Chemical\"}, {\"text\": \"pain\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00742", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Extra caution is warranted in treating infertility patients with CC", "completion": "{\"entities\": [{\"text\": \"infertility\", \"type\": \"Disease\"}, {\"text\": \"CC\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00186", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Triazolam - induced brief episodes of secondary mania in a depressed patient.", "completion": "{\"entities\": [{\"text\": \"Triazolam\", \"type\": \"Chemical\"}, {\"text\": \"mania\", \"type\": \"Disease\"}, {\"text\": \"depressed\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02184", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: As a result, switching to tacrolimus has been reported to be a viable therapeutic option in the setting of cyclosporine - induced TMA.", "completion": "{\"entities\": [{\"text\": \"tacrolimus\", \"type\": \"Chemical\"}, {\"text\": \"cyclosporine\", \"type\": \"Chemical\"}, {\"text\": \"TMA\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04928", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Hallucinations occurred in 4 patients, and an unpleasant sensation (\" empty head \") was also reported by 2 patients.", "completion": "{\"entities\": [{\"text\": \"Hallucinations\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02336", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Together, these results suggest that the beta4 and the alpha3 subunits are mediators of nicotine - induced seizures and hypolocomotion", "completion": "{\"entities\": [{\"text\": \"nicotine\", \"type\": \"Chemical\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}, {\"text\": \"hypolocomotion\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02062", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Both compounds are metabolised in the same way as 1-bromo-1-chloro-2,2,2-trifluoroethane (halothane) to form reactive trifluoroacetyl halide intermediates, which have been implicated in the hepatotoxicity of halothane.", "completion": "{\"entities\": [{\"text\": \"1-bromo-1-chloro-2,2,2-trifluoroethane\", \"type\": \"Chemical\"}, {\"text\": \"halothane\", \"type\": \"Chemical\"}, {\"text\": \"trifluoroacetyl\", \"type\": \"Chemical\"}, {\"text\": \"hepatotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00513", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Oral contraceptives and the risk of myocardial infarction.", "completion": "{\"entities\": [{\"text\": \"Oral contraceptives\", \"type\": \"Chemical\"}, {\"text\": \"myocardial infarction\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04578", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Conversely, brain normetanephrine concentration was increased from saline control by amantadine in the BALB / C mice.", "completion": "{\"entities\": [{\"text\": \"normetanephrine\", \"type\": \"Chemical\"}, {\"text\": \"amantadine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00469", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: To directly examine the importance of growth to Warfarin - induced artery calcification in animals of the same age, 20 - day - old rats were fed for 2 weeks either an ad libitum diet or a 6 - g / d restricted diet that maintains weight but prevents growth.", "completion": "{\"entities\": [{\"text\": \"Warfarin\", \"type\": \"Chemical\"}, {\"text\": \"artery calcification\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00313", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The stone passed spontaneously and was found to contain a triamterene metabolite admixed with uric acid salts.", "completion": "{\"entities\": [{\"text\": \"triamterene\", \"type\": \"Chemical\"}, {\"text\": \"uric acid salts\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00290", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: FANFT - induced cell proliferation in the bladder was significantly suppressed by aspirin co - administration after 4 weeks but not after 12 weeks.", "completion": "{\"entities\": [{\"text\": \"FANFT\", \"type\": \"Chemical\"}, {\"text\": \"aspirin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00575", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: NO - induced migraine attack: strong increase in plasma calcitonin gene-related peptide (CGRP) concentration and negative correlation with platelet serotonin release.", "completion": "{\"entities\": [{\"text\": \"NO\", \"type\": \"Chemical\"}, {\"text\": \"migraine\", \"type\": \"Disease\"}, {\"text\": \"calcitonin gene-related peptide\", \"type\": \"Chemical\"}, {\"text\": \"CGRP\", \"type\": \"Chemical\"}, {\"text\": \"serotonin\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-03377", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Among the 2000 spots compared for statistical difference, 67 spots were significantly changed in abundance and identified using matrix - assisted laser desorption / ionization time - of - flight MS, atmospheric pressure matrix - assisted laser desorption / ionization and HPLC coupled tandem MS (LC / MS / MS ). Out of these 67 proteins, LID significantly changed the expression level of five proteins: alphabeta - crystalin, gamma - enolase, guanidoacetate methyltransferase, vinculin, and proteasome alpha - 2 subunit.", "completion": "{\"entities\": [{\"text\": \"LID\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00806", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The current study prospectively evaluated the magnitude, clinical course, outcome, and prognostic factors in ATT - ALF.", "completion": "{\"entities\": [{\"text\": \"ALF\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03617", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pair fed rats served as controls.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04870", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 9 years, their mean weight was 193.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01133", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The majority of anionic sites (74% in diabetic and 81% in control rats) were found within the lamina rara externa of the glomerular basement membrane.", "completion": "{\"entities\": [{\"text\": \"diabetic\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02976", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 72 ). There was no agreement between the questionnaire and tremor severity (r = 0.", "completion": "{\"entities\": [{\"text\": \"tremor\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01081", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The pathogenesis of 5-fluorouracil neurotoxicity may be due to a Krebs cycle blockade by fluoroacetate and fluorocitrate, thiamine deficiency, or dihydrouracil dehydrogenase deficiency.", "completion": "{\"entities\": [{\"text\": \"5-fluorouracil\", \"type\": \"Chemical\"}, {\"text\": \"neurotoxicity\", \"type\": \"Disease\"}, {\"text\": \"fluoroacetate\", \"type\": \"Chemical\"}, {\"text\": \"fluorocitrate\", \"type\": \"Chemical\"}, {\"text\": \"thiamine\", \"type\": \"Chemical\"}, {\"text\": \"dihydrouracil\", \"type\": \"Chemical\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-05048", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Perhexiline maleate and peripheral neuropathy.", "completion": "{\"entities\": [{\"text\": \"Perhexiline maleate\", \"type\": \"Chemical\"}, {\"text\": \"peripheral neuropathy\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02440", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: HBV viral load was performed with Amplicor HBV Monitor test v2.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03227", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Recent data suggest a preferential selection of immune escape mutants in distinct peripheral blood leukocyte compartments of infected individuals.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01676", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Intracavernous epinephrine: a minimally invasive treatment for priapism in the emergency department.", "completion": "{\"entities\": [{\"text\": \"epinephrine\", \"type\": \"Chemical\"}, {\"text\": \"priapism\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01303", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These data indicate that the free ED50 in plasma for terfenadine (1.", "completion": "{\"entities\": [{\"text\": \"terfenadine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01904", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Moderate abnormalities require a reduction of deferoxamine to 25 mg / kg per dose with careful monitoring.", "completion": "{\"entities\": [{\"text\": \"deferoxamine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01688", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: o .) together for 30 consecutive days and challenged with ISO on the day 29th and 30th, showed a significant (P < 0.", "completion": "{\"entities\": [{\"text\": \"ISO\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04037", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: of these well validated cases occurred within the first 10 days after treatment.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03827", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Ophthalmological examinations in over 1100 patients treated with one or the other agent have revealed no evidence of significant short term (up to 2 years) cataractogenic potential.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02233", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 001) and repeated administration (280 +/- 17 vs.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04111", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: We performed a case control study of heart failure patients treated with spironolactone in our clinical practice.", "completion": "{\"entities\": [{\"text\": \"heart failure\", \"type\": \"Disease\"}, {\"text\": \"spironolactone\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01532", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: p .) and diazepam (1 mg / kg, i.", "completion": "{\"entities\": [{\"text\": \"diazepam\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00730", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 8 - fold increased risk of thrombosis in females.", "completion": "{\"entities\": [{\"text\": \"thrombosis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00736", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: PATIENT (S ): A 36 - year - old woman referred from the infertility clinic for blurred vision.", "completion": "{\"entities\": [{\"text\": \"infertility\", \"type\": \"Disease\"}, {\"text\": \"blurred vision\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00874", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: v .) decreased blood pressure and heart rate after extracerebral decarboxylase inhibition with MK-486 (25 mg / kg i.", "completion": "{\"entities\": [{\"text\": \"MK-486\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00712", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: OBJECTIVES: To correlate optical density and percent inhibition of a two - step heparin - induced thrombocytopenia (HIT) antigen assay with thrombosis; the assay utilizes reaction inhibition characteristics of a high heparin concentration.", "completion": "{\"entities\": [{\"text\": \"heparin\", \"type\": \"Chemical\"}, {\"text\": \"thrombocytopenia\", \"type\": \"Disease\"}, {\"text\": \"HIT\", \"type\": \"Disease\"}, {\"text\": \"thrombosis\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03151", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: Cisplatin - based chemotherapy combinations improve quality of life and survival in advanced nonsmall cell lung carcinoma (NSCLC ). The emergence of new active drugs might translate into more effective regimens for the treatment of this disease.", "completion": "{\"entities\": [{\"text\": \"Cisplatin\", \"type\": \"Chemical\"}, {\"text\": \"nonsmall cell lung carcinoma\", \"type\": \"Disease\"}, {\"text\": \"NSCLC\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-05065", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It is also suggested from collected evidence that the activity - increasing effects of morphine in mice are mediated by mechanisms different from those which mediate the activity - increasing effects of morphine", "completion": "{\"entities\": [{\"text\": \"morphine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00943", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Her incontinence resolved with the change of medication.", "completion": "{\"entities\": [{\"text\": \"incontinence\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01435", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In conclusion, CPA, diazepam and 2PAM in combination with atropine prevented the occurrence of serious signs of poisoning and thus reduced the toxicity of DFP", "completion": "{\"entities\": [{\"text\": \"CPA\", \"type\": \"Chemical\"}, {\"text\": \"diazepam\", \"type\": \"Chemical\"}, {\"text\": \"2PAM\", \"type\": \"Chemical\"}, {\"text\": \"atropine\", \"type\": \"Chemical\"}, {\"text\": \"poisoning\", \"type\": \"Disease\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}, {\"text\": \"DFP\", \"type\": \"Chemical\"}]}", "n_entities": 7}
{"ref": "bc5cdr-train-00088", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: When instilled directly into the bladder, CAA exerts urotoxic effects, it is, however, susceptible to detoxification with mesna", "completion": "{\"entities\": [{\"text\": \"CAA\", \"type\": \"Chemical\"}, {\"text\": \"mesna\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00476", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the current study, we investigated the synergy between these 2 treatments and found that concurrent Warfarin administration dramatically increased the extent of calcification in the media of vitamin D - treated rats at 3 and 4 days.", "completion": "{\"entities\": [{\"text\": \"Warfarin\", \"type\": \"Chemical\"}, {\"text\": \"calcification\", \"type\": \"Disease\"}, {\"text\": \"vitamin D\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01589", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Direct inhibition of cardiac hyperpolarization - activated cyclic nucleotide - gated pacemaker channels by clonidine.", "completion": "{\"entities\": [{\"text\": \"cyclic nucleotide\", \"type\": \"Chemical\"}, {\"text\": \"clonidine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01203", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It is postulated that her death was caused by hypersensitivity to suxamethonium", "completion": "{\"entities\": [{\"text\": \"death\", \"type\": \"Disease\"}, {\"text\": \"hypersensitivity\", \"type\": \"Disease\"}, {\"text\": \"suxamethonium\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03999", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These findings demonstrate that some neuroactive steroids attenuate convulsant and sensitizing properties of cocaine", "completion": "{\"entities\": [{\"text\": \"steroids\", \"type\": \"Chemical\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03985", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Maternal toxicity, intrauterine growth retardation, and increase of external and skeletal variations were found in rats treated with the highest dose of piroxicam.", "completion": "{\"entities\": [{\"text\": \"toxicity\", \"type\": \"Disease\"}, {\"text\": \"intrauterine growth retardation\", \"type\": \"Disease\"}, {\"text\": \"increase of external and skeletal variations\", \"type\": \"Disease\"}, {\"text\": \"piroxicam\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02877", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The results suggest the existence of residual beneficial clinical aftereffects of consecutive daily applications of low - frequency rTMS on dyskinesias in PD", "completion": "{\"entities\": [{\"text\": \"dyskinesias\", \"type\": \"Disease\"}, {\"text\": \"PD\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04268", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Electron microscopical immunohistochemistry revealed positive reaction products noted on the secretory granules, Golgi cisternae, and endoplasmic reticulum of the untreated rat prolactinoma cells.", "completion": "{\"entities\": [{\"text\": \"prolactinoma\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03361", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: Seventeen subjects who were genotyped as CYP2D6 extensive metabolizers were enrolled in this randomized, open - label, crossover study to receive a single oral dose of desipramine (50 mg) on two separate occasions, once alone and once after multiple doses of cinacalcet (90 mg for 7 days ). Blood samples were obtained predose and up to 72 h postdose.", "completion": "{\"entities\": [{\"text\": \"desipramine\", \"type\": \"Chemical\"}, {\"text\": \"cinacalcet\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02993", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: UM-272 (N,N-dimethylpropranolol ), a quaternary antiarrhythmic agent, was administered sublingually to dogs with ouabain - induced ventricular tachycardias.", "completion": "{\"entities\": [{\"text\": \"UM-272\", \"type\": \"Chemical\"}, {\"text\": \"N,N-dimethylpropranolol\", \"type\": \"Chemical\"}, {\"text\": \"ouabain\", \"type\": \"Chemical\"}, {\"text\": \"ventricular tachycardias\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02247", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: He was awake, revealed no changes of mental status and at rest there were no further motor symptoms.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02506", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: MRI demonstrated hyperintense T2 signals in the cervical cord and right brachial plexus roots indicative of both myelitis and right brachial plexitis.", "completion": "{\"entities\": [{\"text\": \"myelitis\", \"type\": \"Disease\"}, {\"text\": \"brachial plexitis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01092", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Medications were discontinued when erythema multiforme and congestive heart failure caused by myocarditis occurred.", "completion": "{\"entities\": [{\"text\": \"erythema multiforme\", \"type\": \"Disease\"}, {\"text\": \"congestive heart failure\", \"type\": \"Disease\"}, {\"text\": \"myocarditis\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00017", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Six additional patients received a 30 - mg i.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04512", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 1 %) had putaminal hemorrhage, and 8 (57.", "completion": "{\"entities\": [{\"text\": \"putaminal hemorrhage\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02493", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Because the CNS damage caused by METH and MPTP is highly selective for the DA neuronal system in mouse models of neurotoxicity, we hypothesized that the CX3CR1 plays a role in METH - induced neurotoxicity and microglial activation.", "completion": "{\"entities\": [{\"text\": \"CNS damage\", \"type\": \"Disease\"}, {\"text\": \"METH\", \"type\": \"Chemical\"}, {\"text\": \"MPTP\", \"type\": \"Chemical\"}, {\"text\": \"DA\", \"type\": \"Chemical\"}, {\"text\": \"neurotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-reassigned-02709", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: An experimental study in dogs.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04038", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The results of serum liver function tests suggested hepatocellular injury in 10 (63 %); the rest showed a mixed pattern.", "completion": "{\"entities\": [{\"text\": \"hepatocellular injury\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03309", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: The results indicated a favorable therapeutic profile for haloperidol in doses of 2 - 3 mg / day, although a subgroup developed moderate to severe extrapyramidal signs.", "completion": "{\"entities\": [{\"text\": \"haloperidol\", \"type\": \"Chemical\"}, {\"text\": \"extrapyramidal signs\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01009", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 2 %. This resulted in a significant decrease in CMRO2 (to 1.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03122", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Finally, moral issues relating to the testing of potential cocaine", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01178", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: One patient had complete response, seven had stable disease, none had partial response and five had progressive disease.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01045", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Spontaneous resolution occurred following cessation of the drug.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04243", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Of the patients developing one or more recurrences during the first year, only 50% presented with further recurrence once the instillations were stopped.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00875", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: v .) in anesthetize MAO - inhibited dogs.", "completion": "{\"entities\": [{\"text\": \"MAO\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02789", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In four patients HBV DNA levels were higher than normal at baseline.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-05204", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Ticlopidine - induced aplastic anemia: report of three Chinese patients and review of the literature.", "completion": "{\"entities\": [{\"text\": \"Ticlopidine\", \"type\": \"Chemical\"}, {\"text\": \"aplastic anemia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04769", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Seventy patients developed major opportunistic infections whilst on therapy; this was the first AIDS diagnosis in 17.", "completion": "{\"entities\": [{\"text\": \"opportunistic infections\", \"type\": \"Disease\"}, {\"text\": \"AIDS\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02150", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Isoproterenol pretreatment for 15 days caused cardiac hypertrophy without affecting baseline blood pressure and heart rate.", "completion": "{\"entities\": [{\"text\": \"Isoproterenol\", \"type\": \"Chemical\"}, {\"text\": \"cardiac hypertrophy\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01647", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cocaine - induced anxiety was also attenuated in Dbh +/- mice following administration of disulfiram, a dopamine beta - hydroxylase (DBH) inhibitor.", "completion": "{\"entities\": [{\"text\": \"Cocaine\", \"type\": \"Chemical\"}, {\"text\": \"anxiety\", \"type\": \"Disease\"}, {\"text\": \"disulfiram\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02253", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RATIONALE: gamma-Vinyl GABA (GVG) irreversibly inhibits GABA - transaminase.", "completion": "{\"entities\": [{\"text\": \"gamma-Vinyl GABA\", \"type\": \"Chemical\"}, {\"text\": \"GABA\", \"type\": \"Chemical\"}, {\"text\": \"GVG\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04716", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Ophthalmologists at 15 institutions responded, reporting a total of 3, 774 indocyanine green angiograms performed on 2, 820 patients between June 1984 and September 1992.", "completion": "{\"entities\": [{\"text\": \"indocyanine green\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04873", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Five hundred fifty - three patients, 264 taking the lozenge and 289 taking the gum, used the study product for > or = 4 days per week during the first 2 weeks (evaluable population ). The nicotine lozenge and nicotine gum were equally well tolerated, despite increased nicotine exposure from the lozenge.", "completion": "{\"entities\": [{\"text\": \"nicotine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02314", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 01 - 1 mm) applied to oral or nasal mucosa induced increases in dural and cortical blood flow and provoked lacrimation.", "completion": "{\"entities\": [{\"text\": \"increases in dural and cortical blood flow\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04773", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Most patients showed improvement in individual parameters and global score of quality of life.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00620", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We found that (i) gabapentin reduced the activations in the bilateral operculoinsular cortex, independently of the presence of central sensitization ;(ii) gabapentin reduced the activation in the brainstem, only during central sensitization ;(iii) gabapentin suppressed stimulus - induced deactivations, only during central sensitization; this effect was more robust than the effect on brain activation.", "completion": "{\"entities\": [{\"text\": \"gabapentin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05084", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Efficacy was evaluated using the Clinical Global Impression - Sexual Function (CGI - SF; the primary outcome measure ), the International Index of Erectile Function (IIEF ), Arizona Sexual Experience Scale (ASEX ), and Erectile Dysfunction Inventory of Treatment Satisfaction (EDITS )(secondary outcome measures ). Participants were followed biweekly during study period.", "completion": "{\"entities\": [{\"text\": \"Erectile Dysfunction\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04305", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The finding that cocaine - and BE - induced seizures differ in several respects suggests more than one mechanism for cocaine - induced seizures and emphasizes the importance of a cocaine metabolite, BE", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"BE\", \"type\": \"Chemical\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04967", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Visual analogue scores (mean +/- SD) during induction were lower in Groups L (3.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02054", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: Currently accepted intravitreal antibiotic regimens may cause retinal toxicity and macular ischaemia.", "completion": "{\"entities\": [{\"text\": \"retinal toxicity\", \"type\": \"Disease\"}, {\"text\": \"ischaemia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02113", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 243 cocaine - dependent outpatients with cocaine - induced mood disorder (CIMD ), other mood disorders, or no mood disorder were compared on measures of psychiatric symptoms.", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"mood disorder\", \"type\": \"Disease\"}, {\"text\": \"CIMD\", \"type\": \"Disease\"}, {\"text\": \"mood disorders\", \"type\": \"Disease\"}, {\"text\": \"psychiatric\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-00311", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Triamterene nephrolithiasis complicating dyazide therapy.", "completion": "{\"entities\": [{\"text\": \"Triamterene\", \"type\": \"Chemical\"}, {\"text\": \"nephrolithiasis\", \"type\": \"Disease\"}, {\"text\": \"dyazide\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01261", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Many new serotonergic antidepressants have been introduced over the past decade.", "completion": "{\"entities\": [{\"text\": \"serotonergic antidepressants\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03984", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The pooled statistical analysis for ventricular septal (VSD) and midline (MD) defects was performed for rat fetuses exposed to piroxicam, selective and non - selective COX - 2 inhibitor based on present and historic data.", "completion": "{\"entities\": [{\"text\": \"ventricular septal (VSD) and midline (MD) defects\", \"type\": \"Disease\"}, {\"text\": \"piroxicam\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01907", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Flurbiprofen in the treatment of juvenile rheumatoid arthritis.", "completion": "{\"entities\": [{\"text\": \"Flurbiprofen\", \"type\": \"Chemical\"}, {\"text\": \"juvenile rheumatoid arthritis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02829", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This unwanted effect on postural blood pressure was not the result of underlying autonomic failure.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01888", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This was followed by ventricular fibrillation in one patient and sudden death in another.", "completion": "{\"entities\": [{\"text\": \"ventricular fibrillation\", \"type\": \"Disease\"}, {\"text\": \"sudden death\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02488", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Methamphetamine - induced neurotoxicity and microglial activation are not mediated by fractalkine receptor signaling.", "completion": "{\"entities\": [{\"text\": \"Methamphetamine\", \"type\": \"Chemical\"}, {\"text\": \"neurotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02862", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Capsaicin - induced muscle pain alters the excitability of the human jaw - stretch reflex.", "completion": "{\"entities\": [{\"text\": \"Capsaicin\", \"type\": \"Chemical\"}, {\"text\": \"muscle pain\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00217", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Review of this and previously reported cases indicates the need for early diagnosis of amiodarone pneumonitis, immediate withdrawal of amiodarone, and prompt but continued steroid", "completion": "{\"entities\": [{\"text\": \"amiodarone\", \"type\": \"Chemical\"}, {\"text\": \"pneumonitis\", \"type\": \"Disease\"}, {\"text\": \"steroid\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02889", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Repeated trimipramine induces dopamine D2 / D3 and alpha1 - adrenergic up - regulation.", "completion": "{\"entities\": [{\"text\": \"trimipramine\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00341", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Proteinuria was evident at day 5, peaked at day 7 and persisted to day 27.", "completion": "{\"entities\": [{\"text\": \"Proteinuria\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03525", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 9 ml ). In addition 3D gradient echo data sets from 10 healthy male and 10 healthy female age - matched volunteers were used to compare cerebellar volumes.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02645", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: PAN glomeruli already showed significant pathology by day 4, despite relatively mild proteinuria", "completion": "{\"entities\": [{\"text\": \"proteinuria\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03782", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cephalosporin antibiotics cause a variety of hematologic disturbances in man, the pathogeneses and hematopathology of which remain poorly characterized.", "completion": "{\"entities\": [{\"text\": \"Cephalosporin\", \"type\": \"Chemical\"}, {\"text\": \"hematologic disturbances\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01657", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: There were no suggestions of interactions between clonidine and methylphenidate regarding cardiovascular outcomes.", "completion": "{\"entities\": [{\"text\": \"clonidine\", \"type\": \"Chemical\"}, {\"text\": \"methylphenidate\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01568", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSION: Our results suggest that high - dose testosterone therapy may adversely affect atherosclerosis", "completion": "{\"entities\": [{\"text\": \"testosterone\", \"type\": \"Chemical\"}, {\"text\": \"atherosclerosis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02839", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pain memory is thought to affect future pain sensitivity and thus contribute to clinical pain conditions.", "completion": "{\"entities\": [{\"text\": \"Pain\", \"type\": \"Disease\"}, {\"text\": \"pain\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03394", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The typical signs of VPA - induced encephalopathy are impaired consciousness, sometimes marked EEG background slowing, increased seizure frequency, with or without hyperammonemia.", "completion": "{\"entities\": [{\"text\": \"VPA\", \"type\": \"Chemical\"}, {\"text\": \"encephalopathy\", \"type\": \"Disease\"}, {\"text\": \"impaired consciousness\", \"type\": \"Disease\"}, {\"text\": \"seizure\", \"type\": \"Disease\"}, {\"text\": \"hyperammonemia\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-02135", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Changes of sodium and ATP affinities of the cardiac (Na, K )- ATPase during and after nitric oxide deficient hypertension.", "completion": "{\"entities\": [{\"text\": \"sodium\", \"type\": \"Chemical\"}, {\"text\": \"ATP\", \"type\": \"Chemical\"}, {\"text\": \"Na\", \"type\": \"Chemical\"}, {\"text\": \"K\", \"type\": \"Chemical\"}, {\"text\": \"nitric oxide\", \"type\": \"Chemical\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-02955", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: They are almost always benign, but can be mistaken for a serious adverse event by the patient.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00848", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Effects of pallidal neurotensin on haloperidol - induced parkinsonian catalepsy: behavioral and electrophysiological studies.", "completion": "{\"entities\": [{\"text\": \"neurotensin\", \"type\": \"Chemical\"}, {\"text\": \"haloperidol\", \"type\": \"Chemical\"}, {\"text\": \"parkinsonian catalepsy\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03069", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The patient developed RS during dose reduction of risperidone.", "completion": "{\"entities\": [{\"text\": \"RS\", \"type\": \"Disease\"}, {\"text\": \"risperidone\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-02943", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Transmural myocardial infarction with sumatriptan.", "completion": "{\"entities\": [{\"text\": \"myocardial infarction\", \"type\": \"Disease\"}, {\"text\": \"sumatriptan\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04994", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A control group was included for comparison with the lower dose range of glycopyrrolate and atropine.", "completion": "{\"entities\": [{\"text\": \"glycopyrrolate\", \"type\": \"Chemical\"}, {\"text\": \"atropine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02595", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Seventy - one participants completed 2 separate study days and were blind to medication condition (placebo, 10 - mg oxycodone ). Plasma oxycodone concentration peaked between 60 and 90 minutes postdose (P <. 01) and pupil size, an indication of physiological effects of the medication, peaked at approximately 90 to 120 minutes postdose (P <. 01 ). Significant declines in simple and sustained attention, working memory, and verbal memory were observed at 1 hour postdose compared to baseline for both age groups with a trend toward return to baseline by 5 hours postdose.", "completion": "{\"entities\": [{\"text\": \"oxycodone\", \"type\": \"Chemical\"}, {\"text\": \"declines in simple and sustained attention, working memory, and verbal memory\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01703", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: o .) blocked hyperactivity induced by the non - competitive NMDA receptor antagonist, MK-801 and partially reversed spontaneous hyperactivity of NMDA Nr1 (neo -/-) mice.", "completion": "{\"entities\": [{\"text\": \"hyperactivity\", \"type\": \"Disease\"}, {\"text\": \"NMDA\", \"type\": \"Chemical\"}, {\"text\": \"MK-801\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01490", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Of those, 13 (26 %) developed biliary pathology.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01591", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Activation of presynaptic alpha2 - adrenoceptors is the most widely accepted mechanism of action of the antisympathetic drug clonidine; however, other target proteins have been postulated to contribute to the in vivo actions of clonidine.", "completion": "{\"entities\": [{\"text\": \"clonidine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03593", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We wanted to study whether tAMCA retains its convulsive action if incorporated into a FS.", "completion": "{\"entities\": [{\"text\": \"tAMCA\", \"type\": \"Chemical\"}, {\"text\": \"convulsive\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04908", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Serologic evaluation revealed the presence of perinuclear - staining antineutrophil cytoplasmic autoantibodies (pANCA) against myeloperoxidase (MPO ). Propylthiouracil therapy was withdrawn, and she was treated with a 1 - month course of prednisone, which alleviated her symptoms.", "completion": "{\"entities\": [{\"text\": \"Propylthiouracil\", \"type\": \"Chemical\"}, {\"text\": \"prednisone\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05203", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We conclude that GLEPP1 expression, unlike podocalyxin, reflects podocyte injury induced by PAN", "completion": "{\"entities\": [{\"text\": \"PAN\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-reassigned-05757", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Patients with ADSD were identified.", "completion": "{\"entities\": [{\"text\": \"ADSD\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01498", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Swiss albino mice prepared with intrajugular catheters were tested in photocell cages after administration of 93 mg / kg (LD50) of cocaine and GNC92H2 infusions ranging from 30 to 190 mg / kg.", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"GNC92H2\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02133", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These defects explain the abnormal erythrocyte shape and decreased mechanical stability promoted by TAM, resulting in hemolytic anemia.", "completion": "{\"entities\": [{\"text\": \"TAM\", \"type\": \"Chemical\"}, {\"text\": \"hemolytic anemia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01369", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The risk of venous thromboembolism in women prescribed cyproterone acetate in combination with ethinyl estradiol: a nested cohort analysis and case - control study.", "completion": "{\"entities\": [{\"text\": \"venous thromboembolism\", \"type\": \"Disease\"}, {\"text\": \"cyproterone acetate\", \"type\": \"Chemical\"}, {\"text\": \"ethinyl estradiol\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02693", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A repeat work - up revealed further elevations in aminotransferase levels, and liver biopsy revealed evidence of moderate - to - severe drug toxicity.", "completion": "{\"entities\": [{\"text\": \"drug toxicity\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02255", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: OBJECTIVES: Given its preclinical success for treating substance abuse and the increased risk of visual field defects (VFD) associated with cumulative lifetime exposure, we explored the effects of sub - chronic low dose GVG on cocaine - induced increases in nucleus accumbens (NAcc) dopamine (DA ). METHODS: Using in vivo microdialysis, we compared acute exposure (450 mg / kg) to an identical sub - chronic exposure (150 mg / kg per day for 3 days ), followed by 1 - or 3 - day washout.", "completion": "{\"entities\": [{\"text\": \"substance abuse\", \"type\": \"Disease\"}, {\"text\": \"visual field defects\", \"type\": \"Disease\"}, {\"text\": \"VFD\", \"type\": \"Disease\"}, {\"text\": \"GVG\", \"type\": \"Chemical\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}, {\"text\": \"DA\", \"type\": \"Chemical\"}]}", "n_entities": 7}
{"ref": "bc5cdr-train-03355", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: MPEP administered into the striatum at high concentrations (500 microM) increased extracellular dopamine levels, while lower concentrations (50 - 100 microM) were devoid of any effect.", "completion": "{\"entities\": [{\"text\": \"MPEP\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03865", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 034 ). Pain severity and analgesic requirements were unaffected by the omission of fentanyl.", "completion": "{\"entities\": [{\"text\": \"Pain\", \"type\": \"Disease\"}, {\"text\": \"fentanyl\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01238", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Recurrent use of newer oral contraceptives and the risk of venous thromboembolism.", "completion": "{\"entities\": [{\"text\": \"oral contraceptives\", \"type\": \"Chemical\"}, {\"text\": \"venous thromboembolism\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01859", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Portal plasma concentrations of neither arginine vasopressin nor oxytocin are significantly altered in this paradigm.", "completion": "{\"entities\": [{\"text\": \"arginine vasopressin\", \"type\": \"Chemical\"}, {\"text\": \"oxytocin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05096", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Total ASEX scores were significantly lower, i.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03527", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, multiple regression for the daily dosage, duration of phenytoin treatment and cerebellar volume revealed a correlation of these parameters.", "completion": "{\"entities\": [{\"text\": \"phenytoin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00551", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: OBJECTIVE: To report 2 cases of ticlopidine - induced cholestatic hepatitis, investigate its mechanism, and compare the observed main characteristics with those of the published cases.", "completion": "{\"entities\": [{\"text\": \"ticlopidine\", \"type\": \"Chemical\"}, {\"text\": \"cholestatic hepatitis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01797", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The incidence calculation revealed that one of 215 therapeutic users had reactions, compared with one of 13, 000 in the prophylaxis group, making the risk of neuropsychiatric reactions after mefloquine treatment 60 times higher than after prophylaxis.", "completion": "{\"entities\": [{\"text\": \"mefloquine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00103", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In patient 1, plasma levels of deoxycorticosterone and 11-deoxycortisol were elevated.", "completion": "{\"entities\": [{\"text\": \"deoxycorticosterone\", \"type\": \"Chemical\"}, {\"text\": \"11-deoxycortisol\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03213", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A case of massive rhabdomyolysis following molindone administration.", "completion": "{\"entities\": [{\"text\": \"rhabdomyolysis\", \"type\": \"Disease\"}, {\"text\": \"molindone\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03440", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: One hundred and four (104) patients aged 6 - 35 years (mean 17, 2 years) participated in the study.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02538", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: We conducted a retrospective review of 70 consecutive microvascular decompression operations and studied those patients who received topical papaverine for vasospasm.", "completion": "{\"entities\": [{\"text\": \"papaverine\", \"type\": \"Chemical\"}, {\"text\": \"vasospasm\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03218", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cardiovascular alterations in rat fetuses exposed to calcium channel blockers.", "completion": "{\"entities\": [{\"text\": \"Cardiovascular alterations\", \"type\": \"Disease\"}, {\"text\": \"calcium\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01172", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Each course of chemotherapy was given every 4 weeks.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02680", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Extrapyramidal side effects with risperidone and haloperidol at comparable D2 receptor occupancy levels.", "completion": "{\"entities\": [{\"text\": \"risperidone\", \"type\": \"Chemical\"}, {\"text\": \"haloperidol\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02175", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Ketamine reduced both the area of brush - evoked and punctate - evoked hyperalgesia significantly and it tended to reduce brush - evoked pain.", "completion": "{\"entities\": [{\"text\": \"Ketamine\", \"type\": \"Chemical\"}, {\"text\": \"hyperalgesia\", \"type\": \"Disease\"}, {\"text\": \"pain\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03378", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Complementary techniques such as western immunoblotting and immunohistochemistry were performed to investigate the validity of the data obtained using the proteomic approach.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01934", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The rats were trained to swim for a specific duration and for a particular period.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01570", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Sirolimus is a novel immunosuppressant with potent antiproliferative actions through its ability to inhibit the raptor - containing mammalian target of rapamycin protein kinase.", "completion": "{\"entities\": [{\"text\": \"Sirolimus\", \"type\": \"Chemical\"}, {\"text\": \"rapamycin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05224", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Drug - induced gross activity counts were increased in the novel exploratory box only, while measures of stereotypic behavior were similar in both.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04916", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We measured diazepam - induced anxiolysis with the elevated plus - maze test, diazepam - induced sedation by recording the vigilance states, and picrotoxin - and pentylenetetrazol - induced seizures after i.", "completion": "{\"entities\": [{\"text\": \"diazepam\", \"type\": \"Chemical\"}, {\"text\": \"picrotoxin\", \"type\": \"Chemical\"}, {\"text\": \"pentylenetetrazol\", \"type\": \"Chemical\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01094", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Macrophage - migration inhibition (MIF) test with ampicillin was positive.", "completion": "{\"entities\": [{\"text\": \"ampicillin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04586", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: No hepatic preneoplastic nodules or hepatocellular carcinomas developed in rats fed the plain choline - supplemented diet, while one preneoplastic nodule and one hepatocellular carcinoma developed in two rats fed the same diet containing phenobarbital.", "completion": "{\"entities\": [{\"text\": \"hepatocellular carcinoma\", \"type\": \"Disease\"}, {\"text\": \"hepatocellular carcinomas\", \"type\": \"Disease\"}, {\"text\": \"choline\", \"type\": \"Chemical\"}, {\"text\": \"phenobarbital\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-reassigned-03466", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 nmol mouse - 1, i.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01607", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Comparisons between exposed newborns' subgroups revealed no significant differences.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00760", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Moreover, a positive correlation of histamine to gastric hemorrhage and to ulcer was found in those atherosclerotic rats.", "completion": "{\"entities\": [{\"text\": \"histamine\", \"type\": \"Chemical\"}, {\"text\": \"gastric hemorrhage\", \"type\": \"Disease\"}, {\"text\": \"ulcer\", \"type\": \"Disease\"}, {\"text\": \"atherosclerotic\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-reassigned-04987", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 1 %) than with HCTZ monotherapies (7.", "completion": "{\"entities\": [{\"text\": \"HCTZ\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03758", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Grade less than or equal to 2 nausea and vomiting occurred in 66% courses and phlebitis in the infusion arm in 37 %. 1 patient with squamous cell carcinoma achieved a partial response lasting 5 months.", "completion": "{\"entities\": [{\"text\": \"nausea\", \"type\": \"Disease\"}, {\"text\": \"vomiting\", \"type\": \"Disease\"}, {\"text\": \"phlebitis\", \"type\": \"Disease\"}, {\"text\": \"squamous cell carcinoma\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04339", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: MMP - 2, MMP - 9, ADAM - 10 and ADAM - 17 mRNA levels were increased in CaCl(2) - treated segments (all p < 0.", "completion": "{\"entities\": [{\"text\": \"CaCl(2)\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03932", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Warfarin - induced iliopsoas hemorrhage with subsequent femoral nerve palsy.", "completion": "{\"entities\": [{\"text\": \"Warfarin\", \"type\": \"Chemical\"}, {\"text\": \"hemorrhage\", \"type\": \"Disease\"}, {\"text\": \"femoral nerve palsy\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01016", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: An allergic reaction consisting of angioneurotic edema secondary to continuous infusion 5-fluorouracil occurred in a patient with recurrent carcinoma of the oral cavity, cirrhosis, and cisplatin - induced impaired renal function.", "completion": "{\"entities\": [{\"text\": \"allergic reaction\", \"type\": \"Disease\"}, {\"text\": \"angioneurotic edema\", \"type\": \"Disease\"}, {\"text\": \"5-fluorouracil\", \"type\": \"Chemical\"}, {\"text\": \"carcinoma of the oral cavity\", \"type\": \"Disease\"}, {\"text\": \"cirrhosis\", \"type\": \"Disease\"}, {\"text\": \"cisplatin\", \"type\": \"Chemical\"}, {\"text\": \"impaired renal function\", \"type\": \"Disease\"}]}", "n_entities": 7}
{"ref": "bc5cdr-train-01276", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In addition to renal allografts with TG, we also examined grafts with acute rejection, recurrent glomerulonephritis, chronic allograft nephropathy and stable grafts (\" protocol biopsies \"). Native kidney specimens included a wide range of glomerulopathies as well as cases of thrombotic microangiopathy, malignant hypertension, acute interstitial nephritis, and acute tubular necrosis.", "completion": "{\"entities\": [{\"text\": \"TG\", \"type\": \"Disease\"}, {\"text\": \"glomerulonephritis\", \"type\": \"Disease\"}, {\"text\": \"chronic allograft nephropathy\", \"type\": \"Disease\"}, {\"text\": \"glomerulopathies\", \"type\": \"Disease\"}, {\"text\": \"thrombotic microangiopathy\", \"type\": \"Disease\"}, {\"text\": \"malignant hypertension\", \"type\": \"Disease\"}, {\"text\": \"interstitial nephritis\", \"type\": \"Disease\"}, {\"text\": \"acute tubular necrosis\", \"type\": \"Disease\"}]}", "n_entities": 8}
{"ref": "bc5cdr-train-03226", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Immune escape variants of the hepatitis B virus (HBV) represent an emerging clinical challenge, because they can be associated with vaccine escape, HBV reactivation, and failure of diagnostic tests.", "completion": "{\"entities\": [{\"text\": \"hepatitis B\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02262", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In ICH intrastriatally induced by 0.", "completion": "{\"entities\": [{\"text\": \"ICH\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03686", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Biochemical liver function tests indicated hepatocellular necrosis and correlated with histopathological evidence of hepatic injury, the spectrum of which ranged from fatty change and focal hepatocellular necrosis to massive hepatic necrosis.", "completion": "{\"entities\": [{\"text\": \"necrosis\", \"type\": \"Disease\"}, {\"text\": \"hepatic injury\", \"type\": \"Disease\"}, {\"text\": \"fatty change\", \"type\": \"Disease\"}, {\"text\": \"massive hepatic necrosis\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01509", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Three months of raloxifene treatment was associated with a significant decrease in the plasma TAFI antigen concentrations (16% change, P < 0.", "completion": "{\"entities\": [{\"text\": \"raloxifene\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01763", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We performed a preliminary study in order to determine any difference between a non selective beta - blocker (timolol) and a selective beta - blocker (betaxolol) regarding CNS side effects.", "completion": "{\"entities\": [{\"text\": \"timolol\", \"type\": \"Chemical\"}, {\"text\": \"betaxolol\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02229", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: metamizol in acutely and chronically treated (once a day for 12 days) rats.", "completion": "{\"entities\": [{\"text\": \"metamizol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03640", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: The reported use of antibacterials increased during pregnancy, peaking during the third month.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-reassigned-03191", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: during both rebreathing manoeuvres.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01801", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: To determine if the addition of a buffering solution to adjust the pH of lidocaine into the physiologic range would reduce pain during injection, we performed a blinded randomized study in patients undergoing cardiac catheterization.", "completion": "{\"entities\": [{\"text\": \"lidocaine\", \"type\": \"Chemical\"}, {\"text\": \"pain\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-03184", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: During the first test 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01956", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 9 %) or noradrenaline in doses of 4, 12 and 36 micrograms h - 1 kg - 1 was infused for five consecutive days, either intrarenally (by a new technique) or intravenously into rats with one kidney removed.", "completion": "{\"entities\": [{\"text\": \"noradrenaline\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03697", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Primary tumor sites were oropharynx, 10 patients; hypopharynx, four; larynx, two; oral cavity, three; unknown primary, two; and nasal cavity and parotid gland, one each.", "completion": "{\"entities\": [{\"text\": \"tumor\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03602", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 mg / ml) only evoked brief episodes of jerk - correlated convulsive potentials in 1 of 6 rats.", "completion": "{\"entities\": [{\"text\": \"convulsive\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03756", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Patients had a median performance status of 1 (WHO ), and median age of 61 years.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01071", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: No significant differences between groups were found at enrollment.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01708", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Together these findings show that the GlyT1 inhibitor, SSR103800", "completion": "{\"entities\": [{\"text\": \"SSR103800\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00559", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Immune mechanisms may be involved in the drug' s hepatotoxicity, as suggested by the T - cell stimulation study reported here.", "completion": "{\"entities\": [{\"text\": \"hepatotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04139", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 4% for the patients developing ESRD who subsequently received kidney transplants.", "completion": "{\"entities\": [{\"text\": \"ESRD\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01618", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Newborn rats were given terbutaline (10 mg / kg) daily on postnatal days (PN) 2 to 5 or PN 11 to 14 and examined 24 h after the last dose and at PN 30.", "completion": "{\"entities\": [{\"text\": \"terbutaline\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03893", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: p .) 1 h prior to haloperidol resulted in a dose - dependent increase in the catalepsy times (P < 0.", "completion": "{\"entities\": [{\"text\": \"haloperidol\", \"type\": \"Chemical\"}, {\"text\": \"catalepsy\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02561", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Serum - and glucocorticoid - inducible kinase 1 in doxorubicin - induced nephrotic syndrome.", "completion": "{\"entities\": [{\"text\": \"doxorubicin\", \"type\": \"Chemical\"}, {\"text\": \"nephrotic syndrome\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04748", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Inappropriate use of carbamazepine and vigabatrin in typical absence seizures.", "completion": "{\"entities\": [{\"text\": \"carbamazepine\", \"type\": \"Chemical\"}, {\"text\": \"vigabatrin\", \"type\": \"Chemical\"}, {\"text\": \"absence seizures\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04664", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Headache relief at 2 h was 75.", "completion": "{\"entities\": [{\"text\": \"Headache\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03079", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The methotrexate was administered as a loading dose of 6, 000 mg / m2 for a period of one hour followed by an infusion of 1, 200 mg / m2 / h for 23 hours.", "completion": "{\"entities\": [{\"text\": \"methotrexate\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03038", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Despite the underlying diseases, the prognosis for drug - induced de novo absence seizure is good because it subsides rapidly after discontinuing the use of the offending drugs.", "completion": "{\"entities\": [{\"text\": \"absence seizure\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03497", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Findings of initial and follow - up MRIs were retrospectively evaluated by 2 neuroradiologists by consensus, to analyze the presence of abnormal signal intensities, their locations, and signal changes on follow - up images.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00054", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Because there seems to exist a scientific rationale for the use of fusidic acid at the cytokine level in inflammatory bowel disease", "completion": "{\"entities\": [{\"text\": \"fusidic acid\", \"type\": \"Chemical\"}, {\"text\": \"inflammatory bowel disease\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04475", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: OBJECTIVE: To assess and characterise the risk of bladder cancer, and its relation to cyclophosphamide, in patients with Wegener's granulomatosis.", "completion": "{\"entities\": [{\"text\": \"bladder cancer\", \"type\": \"Disease\"}, {\"text\": \"cyclophosphamide\", \"type\": \"Chemical\"}, {\"text\": \"Wegener's granulomatosis\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04069", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cardioprotective effect of salvianolic acid A on isoproterenol - induced myocardial infarction in rats.", "completion": "{\"entities\": [{\"text\": \"salvianolic acid A\", \"type\": \"Chemical\"}, {\"text\": \"isoproterenol\", \"type\": \"Chemical\"}, {\"text\": \"myocardial infarction\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-reassigned-05373", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Preventive Services Task Force.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00109", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The lung weights were lower and PaO2 was improved in rats given this enzyme - blocking agent.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00187", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Large doses of triazolam repeatedly induced brief episodes of mania in a depressed elderly woman.", "completion": "{\"entities\": [{\"text\": \"triazolam\", \"type\": \"Chemical\"}, {\"text\": \"mania\", \"type\": \"Disease\"}, {\"text\": \"depressed\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00638", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We conclude that careful screening for medications and underlying conditions predisposing to hypocalcemia is recommended to help prevent severe reactions due to citrate toxicity.", "completion": "{\"entities\": [{\"text\": \"hypocalcemia\", \"type\": \"Disease\"}, {\"text\": \"citrate\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-reassigned-03910", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Median follow - up was 11.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02820", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: p ., or an equal volume of saline for the control group (n = 20 ); 15 minutes later, all the animals were injected with a single 50 mg / kg / i.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01582", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: What is less well known is a phenomenon whereby statins may induce a myopathy, which persists or may progress after stopping the drug.", "completion": "{\"entities\": [{\"text\": \"statins\", \"type\": \"Chemical\"}, {\"text\": \"myopathy\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01692", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A 63 - year - old male experienced sudden diplopia after 9 weeks of administration of pegylated interferon (IFN) alpha-2b and ribavirin for chronic hepatitis C (CHC ). Ophthalmologic examinations showed ptosis on the right upper lid and restricted right eye movement without any other neurological signs.", "completion": "{\"entities\": [{\"text\": \"diplopia\", \"type\": \"Disease\"}, {\"text\": \"pegylated interferon (IFN) alpha-2b\", \"type\": \"Chemical\"}, {\"text\": \"ribavirin\", \"type\": \"Chemical\"}, {\"text\": \"chronic hepatitis C\", \"type\": \"Disease\"}, {\"text\": \"CHC\", \"type\": \"Disease\"}, {\"text\": \"ptosis on the right upper lid\", \"type\": \"Disease\"}, {\"text\": \"restricted right eye movement\", \"type\": \"Disease\"}]}", "n_entities": 7}
{"ref": "bc5cdr-train-04381", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: No changes in haloperidol - induced catalepsy or MK-801 - induced locomotion were seen following PD.", "completion": "{\"entities\": [{\"text\": \"haloperidol\", \"type\": \"Chemical\"}, {\"text\": \"catalepsy\", \"type\": \"Disease\"}, {\"text\": \"MK-801\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04035", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 9, with hepatotoxicity being more common in women.", "completion": "{\"entities\": [{\"text\": \"hepatotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04539", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5, frequent hemorrhaging and detachment of the neural plate from surface ectoderm in the exencephalic head at E15.", "completion": "{\"entities\": [{\"text\": \"hemorrhaging\", \"type\": \"Disease\"}, {\"text\": \"exencephalic\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01627", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: A 20 - year - old male with schizophrenia developed a sudden onset of myocarditis after commencement of clozapine.", "completion": "{\"entities\": [{\"text\": \"schizophrenia\", \"type\": \"Disease\"}, {\"text\": \"myocarditis\", \"type\": \"Disease\"}, {\"text\": \"clozapine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03854", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Omitting fentanyl reduces nausea and vomiting, without increasing pain, after sevoflurane for day surgery.", "completion": "{\"entities\": [{\"text\": \"fentanyl\", \"type\": \"Chemical\"}, {\"text\": \"nausea\", \"type\": \"Disease\"}, {\"text\": \"vomiting\", \"type\": \"Disease\"}, {\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"sevoflurane\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-01776", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Two subsets of patients were identified from this latter group: the first included four patients (5% of the total population) who developed major toxicity resulting in Fanconi's syndrome (TDFS ); and the second group included five patients with elevated beta 2 microglobulinuria and low phosphate reabsorption.", "completion": "{\"entities\": [{\"text\": \"toxicity\", \"type\": \"Disease\"}, {\"text\": \"Fanconi's syndrome\", \"type\": \"Disease\"}, {\"text\": \"TDFS\", \"type\": \"Disease\"}, {\"text\": \"phosphate\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04432", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Experiments with systemic administration of the Pgp substrate phenobarbital and the selective Pgp inhibitor tariquidar in TR (-) rats substantiated that Pgp is functional and compensates for the lack of MRP2 in the BBB.", "completion": "{\"entities\": [{\"text\": \"phenobarbital\", \"type\": \"Chemical\"}, {\"text\": \"tariquidar\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04202", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Sinus arrest associated with continuous - infusion cimetidine.", "completion": "{\"entities\": [{\"text\": \"Sinus arrest\", \"type\": \"Disease\"}, {\"text\": \"cimetidine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02053", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Fundus fluorescein angiography confirmed macular capillary closure and telangiectasis.", "completion": "{\"entities\": [{\"text\": \"fluorescein\", \"type\": \"Chemical\"}, {\"text\": \"telangiectasis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03281", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 001 ), but was significantly lower than SBP in the group treated with Dex alone (P < 0.", "completion": "{\"entities\": [{\"text\": \"Dex\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02446", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 40 x 10 (3) copies / ml, respectively.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01278", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These 13 included cases of malignant hypertension, thrombotic microangiopathy, lupus nephritis, Henoch-Schonlein nephritis, crescentic glomerulonephritis, and cocaine - related acute renal failure.", "completion": "{\"entities\": [{\"text\": \"malignant hypertension\", \"type\": \"Disease\"}, {\"text\": \"thrombotic microangiopathy\", \"type\": \"Disease\"}, {\"text\": \"lupus nephritis\", \"type\": \"Disease\"}, {\"text\": \"Henoch-Schonlein nephritis\", \"type\": \"Disease\"}, {\"text\": \"glomerulonephritis\", \"type\": \"Disease\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"acute renal failure\", \"type\": \"Disease\"}]}", "n_entities": 7}
{"ref": "bc5cdr-train-00927", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: e ., leukopenia and thrombocytopenia) and late normal tissue toxicities (i.", "completion": "{\"entities\": [{\"text\": \"leukopenia\", \"type\": \"Disease\"}, {\"text\": \"thrombocytopenia\", \"type\": \"Disease\"}, {\"text\": \"toxicities\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04694", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The 3 - week sulphasalazine syndrome strikes again.", "completion": "{\"entities\": [{\"text\": \"sulphasalazine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04176", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 03) had them, and none of 30 patients receiving bupivacaine had TNSs.", "completion": "{\"entities\": [{\"text\": \"bupivacaine\", \"type\": \"Chemical\"}, {\"text\": \"TNSs\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03061", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 02% 2-acetylaminofluorene coupled with a necrogenic dose of CCl4.", "completion": "{\"entities\": [{\"text\": \"2-acetylaminofluorene\", \"type\": \"Chemical\"}, {\"text\": \"CCl4\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02063", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We aimed to test whether HCFCs 123 and 124 can result in serious liver disease.", "completion": "{\"entities\": [{\"text\": \"HCFCs 123 and 124\", \"type\": \"Chemical\"}, {\"text\": \"liver disease\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03862", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Combining the two fentanyl groups revealed further significant benefits from the avoidance of opioids, reducing postoperative nausea and vomiting and nausea prior to discharge from 35% and 33% to 22% and 19 %(P = 0.", "completion": "{\"entities\": [{\"text\": \"fentanyl\", \"type\": \"Chemical\"}, {\"text\": \"postoperative nausea and vomiting\", \"type\": \"Disease\"}, {\"text\": \"nausea\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-reassigned-03381", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: No other complications were seen.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04327", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 001 ). SigmaST, the sum of ST - segment elevations in 16 precordial leads, decreased (P less than 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03672", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Sulfonamides and nitrofurantoins were associated with several birth defects", "completion": "{\"entities\": [{\"text\": \"Sulfonamides\", \"type\": \"Chemical\"}, {\"text\": \"nitrofurantoins\", \"type\": \"Chemical\"}, {\"text\": \"birth defects\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03244", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 8 %. However, the threshold (61.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02356", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Methylphenidate is structurally and functionally similar to amphetamine.", "completion": "{\"entities\": [{\"text\": \"Methylphenidate\", \"type\": \"Chemical\"}, {\"text\": \"amphetamine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00621", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The observed drug - induced effects were not due to changes in the baseline fMRI signal.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04566", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Therapeutic ranges for antidepressants", "completion": "{\"entities\": [{\"text\": \"antidepressants\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03630", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cardiac functions were evaluated with radionuclide angiography before chemotherapies.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04862", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: Nicotine polacrilex lozenges deliver 25% to 27% more nicotine compared with equivalent doses of nicotine polacrilex gum.", "completion": "{\"entities\": [{\"text\": \"Nicotine\", \"type\": \"Chemical\"}, {\"text\": \"nicotine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01941", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The effect of a widely used organic solvent, polyethylene glycol 400 (PEG 400 ), on the toxic action of an acute or chronic treatment with adriamycin (ADR) was evaluated in mice.", "completion": "{\"entities\": [{\"text\": \"polyethylene glycol 400\", \"type\": \"Chemical\"}, {\"text\": \"PEG 400\", \"type\": \"Chemical\"}, {\"text\": \"adriamycin\", \"type\": \"Chemical\"}, {\"text\": \"ADR\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01887", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The most common signs of cardiotoxicity were chest pain, ST - T wave changes and atrial fibrillation.", "completion": "{\"entities\": [{\"text\": \"cardiotoxicity\", \"type\": \"Disease\"}, {\"text\": \"chest pain\", \"type\": \"Disease\"}, {\"text\": \"atrial fibrillation\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01431", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: All rats were terminated either 24 h or 3 weeks after the DFP injection.", "completion": "{\"entities\": [{\"text\": \"DFP\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00946", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Myocardial infarction following sublingual administration of isosorbide dinitrate.", "completion": "{\"entities\": [{\"text\": \"Myocardial infarction\", \"type\": \"Disease\"}, {\"text\": \"isosorbide dinitrate\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03629", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thirteen patients with acute leukemia were treated with a DNR - containing regimen.", "completion": "{\"entities\": [{\"text\": \"acute leukemia\", \"type\": \"Disease\"}, {\"text\": \"DNR\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00582", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 01) during the migraine attack and returned to baseline after the cessation of the migraine.", "completion": "{\"entities\": [{\"text\": \"migraine\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02740", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Chronic enalapril treatment reduced blood pressure without reducing albuminuria in group 4.", "completion": "{\"entities\": [{\"text\": \"enalapril\", \"type\": \"Chemical\"}, {\"text\": \"albuminuria\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02343", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It may even present in patients who have tolerated this medicine well in the past.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04303", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Electrical recordings from the hippocampus showed a rhythmic progression in EEG frequency and voltage with clinical seizure expression.", "completion": "{\"entities\": [{\"text\": \"seizure\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00855", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The neurotensin type-1 receptor antagonist SR48692 blocked both the behavioral and the electrophysiological effects induced by neurotensin.", "completion": "{\"entities\": [{\"text\": \"neurotensin\", \"type\": \"Chemical\"}, {\"text\": \"neurotensin type-1 receptor antagonist\", \"type\": \"Chemical\"}, {\"text\": \"SR48692\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00188", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Features of organic mental disorder (delirium) were not present.", "completion": "{\"entities\": [{\"text\": \"organic mental disorder\", \"type\": \"Disease\"}, {\"text\": \"delirium\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02217", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Current estimates suggest that between 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01088", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The results of this case report support the idea that in contrast with carbamazepine oxcarbazepine", "completion": "{\"entities\": [{\"text\": \"carbamazepine\", \"type\": \"Chemical\"}, {\"text\": \"oxcarbazepine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03613", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 mg / kg ). The animals that had experienced cyclic sucrose and chow were hyperactive in response to amphetamine compared with four control groups (ad libitum 10% sucrose and chow followed by amphetamine injection, cyclic chow followed by amphetamine injection, ad libitum chow with amphetamine, or cyclic 10% sucrose and chow with a saline injection ). These results suggest that a diet comprised of alternating deprivation and access to a sugar solution and chow produces bingeing on sugar that leads to a long lasting state of increased sensitivity to amphetamine, possibly due to a lasting alteration in the dopamine", "completion": "{\"entities\": [{\"text\": \"sucrose\", \"type\": \"Chemical\"}, {\"text\": \"hyperactive\", \"type\": \"Disease\"}, {\"text\": \"amphetamine\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01812", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We conducted a 12 - month controlled trial of mazindol, a putative growth hormone secretion inhibitor, in 83 boys with Duchenne dystrophy.", "completion": "{\"entities\": [{\"text\": \"mazindol\", \"type\": \"Chemical\"}, {\"text\": \"Duchenne dystrophy\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01383", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pseudoacromegaly induced by the long - term use of minoxidil.", "completion": "{\"entities\": [{\"text\": \"Pseudoacromegaly\", \"type\": \"Disease\"}, {\"text\": \"minoxidil\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00255", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: There was widespread metastatic calcification in the cows that died.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03074", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Serious adverse effects are uncommon and mainly have been related to the depression of cardiac contractility and conduction, especially when the drug is combined with beta - blocking agents.", "completion": "{\"entities\": [{\"text\": \"depression\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02366", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The proportion of possibly avoidable cases due to drug interactions was estimated.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03606", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A diet promoting sugar dependency causes behavioral cross-sensitization to a low dose of amphetamine.", "completion": "{\"entities\": [{\"text\": \"sugar dependency\", \"type\": \"Disease\"}, {\"text\": \"behavioral cross-sensitization\", \"type\": \"Disease\"}, {\"text\": \"amphetamine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01497", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The therapeutic potential of the anticocaine antibody GNC92H2 was examined using a model of cocaine overdose.", "completion": "{\"entities\": [{\"text\": \"GNC92H2\", \"type\": \"Chemical\"}, {\"text\": \"cocaine overdose\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-02996", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The results indicate that centrally applied AVP", "completion": "{\"entities\": [{\"text\": \"AVP\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04006", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 mg / kg / day (given orally) or SRL 0.", "completion": "{\"entities\": [{\"text\": \"SRL\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02055", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Treatment strategies aimed at avoiding retinal toxicity", "completion": "{\"entities\": [{\"text\": \"retinal toxicity\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01767", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In a double blind cross - over study with control group, the patients under timolol treatment presented higher depression values measured through the Beck and the Zung - Conde scales (p < 0.", "completion": "{\"entities\": [{\"text\": \"timolol\", \"type\": \"Chemical\"}, {\"text\": \"depression\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01484", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 7 ). CONCLUSION: Raloxifene was associated with an increased risk for venous thromboembolism, but there was no increased risk for cataracts, gallbladder disease, endometrial hyperplasia, or endometrial cancer", "completion": "{\"entities\": [{\"text\": \"Raloxifene\", \"type\": \"Chemical\"}, {\"text\": \"venous thromboembolism\", \"type\": \"Disease\"}, {\"text\": \"cataracts\", \"type\": \"Disease\"}, {\"text\": \"gallbladder disease\", \"type\": \"Disease\"}, {\"text\": \"endometrial hyperplasia\", \"type\": \"Disease\"}, {\"text\": \"endometrial cancer\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-00092", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: No early onset migraine was observed.", "completion": "{\"entities\": [{\"text\": \"migraine\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00547", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: When injected into the accumbens shell (but not the core) before cocaine, CP 93129 (0.", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"CP 93129\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03336", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05 ). Baseline renal ACE did not correlate with focal glomerulosclerosis (r = 0.", "completion": "{\"entities\": [{\"text\": \"focal glomerulosclerosis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03964", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thyroid - stimulating hormone, magnesium, and potassium levels were within normal limits, urine drug screen was negative, and alcohol use was denied.", "completion": "{\"entities\": [{\"text\": \"magnesium\", \"type\": \"Chemical\"}, {\"text\": \"potassium\", \"type\": \"Chemical\"}, {\"text\": \"alcohol\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00625", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Fifteen polydrug ecstasy users and 15 polydrug non - ecstasy user controls completed a general drug use questionnaire, the Brixton Spatial Anticipation task (set shifting ), Backward Digit Span procedure (memory updating ), Inhibition of Return (inhibition ), an emotional intelligence scale, the Tromso Social Intelligence Scale and the Dysexecutive Questionnaire (DEX ). Compared with MDMA - free polydrug controls, MDMA polydrug users showed impairments in set shifting and memory updating, and also in social and emotional judgement processes.", "completion": "{\"entities\": [{\"text\": \"ecstasy\", \"type\": \"Chemical\"}, {\"text\": \"MDMA\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03634", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The plasma levels of BNP in all the patients with clinical and subclinical heart failure increased above the normal limit (40 pg / ml) before the detection of clinical or subclinical heart failure by radionuclide angiography.", "completion": "{\"entities\": [{\"text\": \"heart failure\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03878", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Antipsychotic - like profile of thioperamide, a selective H3 - receptor antagonist in mice.", "completion": "{\"entities\": [{\"text\": \"thioperamide\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00700", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A 49 - year - old woman was transferred to our department because of quadriparesis, lancinating pain, sensory loss, and paresthesia of the distal limbs.", "completion": "{\"entities\": [{\"text\": \"quadriparesis\", \"type\": \"Disease\"}, {\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"sensory loss\", \"type\": \"Disease\"}, {\"text\": \"paresthesia\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00265", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Isoniazid was the most frequent agent in drug - induced neuropathy.", "completion": "{\"entities\": [{\"text\": \"Isoniazid\", \"type\": \"Chemical\"}, {\"text\": \"neuropathy\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03996", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Kindled seizures were induced by daily administration of 60 mg / kg cocaine for 5 days.", "completion": "{\"entities\": [{\"text\": \"seizures\", \"type\": \"Disease\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00474", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: High doses of vitamin D are known to cause calcification of the artery media in as little as 3 to 4 days.", "completion": "{\"entities\": [{\"text\": \"vitamin D\", \"type\": \"Chemical\"}, {\"text\": \"calcification of the artery\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01223", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: v .) was also able to prevent antimuscarine - induced amnesia, demonstrating a central localization of the activity.", "completion": "{\"entities\": [{\"text\": \"amnesia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00991", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Drug - induced arterial spasm relieved by lidocaine.", "completion": "{\"entities\": [{\"text\": \"spasm\", \"type\": \"Disease\"}, {\"text\": \"lidocaine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04196", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Effect of nifedipine on renal function in liver transplant recipients receiving tacrolimus.", "completion": "{\"entities\": [{\"text\": \"nifedipine\", \"type\": \"Chemical\"}, {\"text\": \"tacrolimus\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03823", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Lovastatin has been marketed in the United States for over 6 months.", "completion": "{\"entities\": [{\"text\": \"Lovastatin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04012", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The semi - quantitative scoring was significantly worst in the group treated with CsA plus SRL (P < 0.", "completion": "{\"entities\": [{\"text\": \"CsA\", \"type\": \"Chemical\"}, {\"text\": \"SRL\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04893", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The majority of patients (> 60 %) experienced no change in their disease status from baseline.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-05062", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: p ., 24 hr ), a serotonin depletor, caused no significant change in the hyperactivity.", "completion": "{\"entities\": [{\"text\": \"serotonin\", \"type\": \"Chemical\"}, {\"text\": \"hyperactivity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01195", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Suxamethonium - induced cardiac arrest and death following 5 days of immobilization.", "completion": "{\"entities\": [{\"text\": \"Suxamethonium\", \"type\": \"Chemical\"}, {\"text\": \"cardiac arrest\", \"type\": \"Disease\"}, {\"text\": \"death\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04264", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Morphometric analysis revealed that the volume density of secretory granules increased, while the volume density of cytoplasmic microtubules decreased.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00832", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Central nervous system complications during treatment of acute lymphoblastic leukemia in a single pediatric institution.", "completion": "{\"entities\": [{\"text\": \"Central nervous system complications\", \"type\": \"Disease\"}, {\"text\": \"acute lymphoblastic leukemia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04634", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Further signs were hyperhidrosis, hypersalivation, bronchorrhoea, and severe miosis; the electrocardiographic finding was atrio-ventricular dissociation.", "completion": "{\"entities\": [{\"text\": \"hyperhidrosis\", \"type\": \"Disease\"}, {\"text\": \"hypersalivation\", \"type\": \"Disease\"}, {\"text\": \"bronchorrhoea\", \"type\": \"Disease\"}, {\"text\": \"miosis\", \"type\": \"Disease\"}, {\"text\": \"atrio-ventricular dissociation\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-00084", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Based on clinical data, indicating that chloroacetaldehyde (CAA) is an important metabolite of oxazaphosphorine cytostatics, an experimental study was carried out in order to elucidate the role of CAA in the development of hemorrhagic cystitis.", "completion": "{\"entities\": [{\"text\": \"chloroacetaldehyde\", \"type\": \"Chemical\"}, {\"text\": \"CAA\", \"type\": \"Chemical\"}, {\"text\": \"hemorrhagic cystitis\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02863", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The pathophysiology of painful temporomandibular disorders is not fully understood, but evidence suggests that muscle pain modulates motor function in characteristic ways.", "completion": "{\"entities\": [{\"text\": \"temporomandibular disorders\", \"type\": \"Disease\"}, {\"text\": \"muscle pain\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04300", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Treated rats were then evaluated for incidence, latency, and seizure pattern or for locomotor activity in animals without seizures.", "completion": "{\"entities\": [{\"text\": \"seizure\", \"type\": \"Disease\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01658", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Moderate or severe adverse events were more common in subjects on clonidine (79.", "completion": "{\"entities\": [{\"text\": \"clonidine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01262", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Although urinary incontinence is listed as one side effect of these drugs in their package inserts there is only one report in the literature.", "completion": "{\"entities\": [{\"text\": \"urinary incontinence\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-reassigned-03005", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 8 years) underwent heart transplantation.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00215", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: He developed pneumonitis, pleural and pericardial effusions, and a predominantly proximal motor neuropathy.", "completion": "{\"entities\": [{\"text\": \"pneumonitis\", \"type\": \"Disease\"}, {\"text\": \"pleural and pericardial effusions\", \"type\": \"Disease\"}, {\"text\": \"proximal motor neuropathy\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00330", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This patient underwent a 10 - month regimen of rifampin and isoniazid for pulmonary tuberculosis and was discovered to have developed signs of severe renal failure five weeks after completion of therapy.", "completion": "{\"entities\": [{\"text\": \"rifampin\", \"type\": \"Chemical\"}, {\"text\": \"isoniazid\", \"type\": \"Chemical\"}, {\"text\": \"pulmonary tuberculosis\", \"type\": \"Disease\"}, {\"text\": \"renal failure\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01921", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We report the case of a young woman who suffered a cerebral infarction after taking a single oral dose of PPA", "completion": "{\"entities\": [{\"text\": \"cerebral infarction\", \"type\": \"Disease\"}, {\"text\": \"PPA\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04921", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pain not responsive to morphine is often problematic.", "completion": "{\"entities\": [{\"text\": \"Pain\", \"type\": \"Disease\"}, {\"text\": \"morphine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02471", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 9% postswitch (p = 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04385", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This animal model may be useful to explore the mechanisms by which prenatal nutritional deficiency enhances risk for schizophrenia", "completion": "{\"entities\": [{\"text\": \"nutritional deficiency\", \"type\": \"Disease\"}, {\"text\": \"schizophrenia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02212", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Since AAP, AMI and DOX undergo biotransformation and are known to produce damaging radicals in vivo, the protection by GSPE may be linked to both inhibition of metabolism and / or detoxification of cytotoxic radicals.", "completion": "{\"entities\": [{\"text\": \"AAP\", \"type\": \"Chemical\"}, {\"text\": \"AMI\", \"type\": \"Chemical\"}, {\"text\": \"DOX\", \"type\": \"Chemical\"}, {\"text\": \"GSPE\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00829", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 8 mg / dL ), prothrombin time (PT) prolongation (> or = 26 seconds ), and grade III / IV encephalopathy at presentation.", "completion": "{\"entities\": [{\"text\": \"encephalopathy\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03118", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cocaine related chest pain: are we seeing the tip of an iceberg ? The recreational use of cocaine is on the increase.", "completion": "{\"entities\": [{\"text\": \"Cocaine\", \"type\": \"Chemical\"}, {\"text\": \"chest pain\", \"type\": \"Disease\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02886", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Five hours after exposure, he developed disulfiram - like syndrome with flushing, tachycardia, and arterial hypotension after consuming three glasses of wine.", "completion": "{\"entities\": [{\"text\": \"disulfiram\", \"type\": \"Chemical\"}, {\"text\": \"flushing\", \"type\": \"Disease\"}, {\"text\": \"tachycardia\", \"type\": \"Disease\"}, {\"text\": \"arterial hypotension\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04705", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 8 patients developed symptoms of toxicity.", "completion": "{\"entities\": [{\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02044", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Damage to the vascular basement lamina was also observed.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04451", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In this study, we investigated whether increased generation of FR during status epilepticus would be sufficient to provoke abnormalities in mtDNA and in the expression and activity of cytochrome c oxidase (CCO ), complex IV of the respiratory chain, in the chronic phase of the pilocarpine model of temporal lobe epilepsy.", "completion": "{\"entities\": [{\"text\": \"status epilepticus\", \"type\": \"Disease\"}, {\"text\": \"pilocarpine\", \"type\": \"Chemical\"}, {\"text\": \"temporal lobe epilepsy\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04376", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Prenatal protein deprivation alters dopamine - mediated behaviors and dopaminergic and glutamatergic receptor binding.", "completion": "{\"entities\": [{\"text\": \"dopamine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02128", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Hemolysis caused by TAM was not preceded by the leakage of K (+) from the cells, also excluding a colloid - osmotic type mechanism of hemolysis, according to the effects on osmotic fragility curves.", "completion": "{\"entities\": [{\"text\": \"Hemolysis\", \"type\": \"Disease\"}, {\"text\": \"TAM\", \"type\": \"Chemical\"}, {\"text\": \"K\", \"type\": \"Chemical\"}, {\"text\": \"hemolysis\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03907", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: THP exhibited an antipsychotic - like profile by potentiating haloperidol - induced catalepsy, reducing amphetamine - induced hyperactivity and reducing apomorphine - induced climbing in mice.", "completion": "{\"entities\": [{\"text\": \"THP\", \"type\": \"Chemical\"}, {\"text\": \"haloperidol\", \"type\": \"Chemical\"}, {\"text\": \"catalepsy\", \"type\": \"Disease\"}, {\"text\": \"amphetamine\", \"type\": \"Chemical\"}, {\"text\": \"hyperactivity\", \"type\": \"Disease\"}, {\"text\": \"apomorphine\", \"type\": \"Chemical\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-00973", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Glyburide can produce an acute hepatitis-like illness", "completion": "{\"entities\": [{\"text\": \"Glyburide\", \"type\": \"Chemical\"}, {\"text\": \"acute hepatitis-like illness\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01842", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 7 %) and septicaemia (3.", "completion": "{\"entities\": [{\"text\": \"septicaemia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00923", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Effect of adriamycin combined with whole body hyperthermia on tumor and normal tissues.", "completion": "{\"entities\": [{\"text\": \"adriamycin\", \"type\": \"Chemical\"}, {\"text\": \"hyperthermia\", \"type\": \"Disease\"}, {\"text\": \"tumor\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04237", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The tolerance was evaluated in these 110 patients, and 29 patients presented with local side - effects.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00749", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Protective effect of verapamil on gastric hemorrhagic ulcers in severe atherosclerotic rats.", "completion": "{\"entities\": [{\"text\": \"verapamil\", \"type\": \"Chemical\"}, {\"text\": \"gastric hemorrhagic\", \"type\": \"Disease\"}, {\"text\": \"ulcers\", \"type\": \"Disease\"}, {\"text\": \"atherosclerotic\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04648", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Especially in old patients, intensivists should consider intoxications (with cholinergics) as a cause of acute cardiovascular failure", "completion": "{\"entities\": [{\"text\": \"acute cardiovascular failure\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00839", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Safety of capecitabine: a review.", "completion": "{\"entities\": [{\"text\": \"capecitabine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04283", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The first patient died without a diagnosis; the second patient had a dramatic recovery following the administration of vitamin B6", "completion": "{\"entities\": [{\"text\": \"vitamin B6\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01592", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS AND RESULTS: To test whether clonidine elicits pharmacological effects independent of alpha2 - adrenoceptors, we have generated mice with a targeted deletion of all 3 alpha2 - adrenoceptor subtypes (alpha2ABC -/-). Alpha2ABC -/- mice were completely unresponsive to the analgesic and hypnotic effects of clonidine; however, clonidine significantly lowered heart rate in alpha2ABC -/- mice by up to 150 bpm.", "completion": "{\"entities\": [{\"text\": \"clonidine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01919", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Phenylpropanolamine (PPA ), a synthetic sympathomimetic that is structurally similar to amphetamine, is available over the counter in anorectics, nasal congestants, and cold preparations.", "completion": "{\"entities\": [{\"text\": \"Phenylpropanolamine\", \"type\": \"Chemical\"}, {\"text\": \"PPA\", \"type\": \"Chemical\"}, {\"text\": \"amphetamine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00977", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The systemic, central venous, pulmonary capillary wedge pressures, and heart rates, were similar in the two groups.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00223", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Comparison of the subjective effects and plasma concentrations following oral and i.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03541", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: End - diastolic (ED) and end - systolic (ES) LV diameters / BW significantly increased, whereas LV FS was decreased after 9 weeks in the DOX group (p < 0.", "completion": "{\"entities\": [{\"text\": \"DOX\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01746", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 827 counts per minute per gram of dried tissue or fraction ). Myocardial concentrations of calcium also increased significantly (12.", "completion": "{\"entities\": [{\"text\": \"calcium\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04577", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Treatment with amantadine did not alter whole brain dopamine levels but decreased the amounts of 3,4-dihydroxyphenylacetic acid in the BALB / C mice compared to saline control.", "completion": "{\"entities\": [{\"text\": \"amantadine\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}, {\"text\": \"3,4-dihydroxyphenylacetic acid\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03499", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: All the lesions in dentate, inferior colliculus, pons, and medullas had been resolved completely on follow - up MRIs in 5 patients, but in 1 patient of them, corpus callosal lesion persisted.", "completion": "{\"entities\": [{\"text\": \"callosal lesion\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02107", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Intake of appetite suppressants", "completion": "{\"entities\": [{\"text\": \"appetite suppressants\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04497", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Plasma cortisol concentrations were significantly raised during the active phase (323 +/- 43 to 1082 +/- 245 mmol / L, P < 0.", "completion": "{\"entities\": [{\"text\": \"cortisol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02713", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This case illustrates a number of problems that may be encountered in women with eating disorders in pregnancy, including prolonged and recurrent metabolic disturbances and diuretic abuse.", "completion": "{\"entities\": [{\"text\": \"eating disorders\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03190", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: International mexiletine and placebo antiarrhythmic coronary trial: I.", "completion": "{\"entities\": [{\"text\": \"mexiletine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04480", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: The median cumulative doses of cyclophosphamide among cases (n = 11) and controls (n = 25) were 113 g and 25 g, respectively.", "completion": "{\"entities\": [{\"text\": \"cyclophosphamide\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01575", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The mechanisms of sirolimus - associated proteinuria are multifactorial and may be due to an increase in glomerular capillary pressure following calcineurin inhibitor withdrawal.", "completion": "{\"entities\": [{\"text\": \"sirolimus\", \"type\": \"Chemical\"}, {\"text\": \"proteinuria\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05067", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The clinical utility of FK 506 is complicated by substantial hypertension and nephrotoxicity.", "completion": "{\"entities\": [{\"text\": \"FK 506\", \"type\": \"Chemical\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}, {\"text\": \"nephrotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00270", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A double - blind study of the efficacy and safety of dothiepin hydrochloride in the treatment of major depressive disorder.", "completion": "{\"entities\": [{\"text\": \"dothiepin hydrochloride\", \"type\": \"Chemical\"}, {\"text\": \"depressive disorder\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02991", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Clinicians should be aware of this potential complication when adding thalidomide", "completion": "{\"entities\": [{\"text\": \"thalidomide\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02691", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A routine laboratory work - up 10 weeks after conversion revealed elevated serum aminotransferase levels.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01853", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Dipyridamole - induced myocardial ischemia.", "completion": "{\"entities\": [{\"text\": \"Dipyridamole\", \"type\": \"Chemical\"}, {\"text\": \"myocardial ischemia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05172", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the present work we assessed the effect of treatment of rats with gum Arabic on acute renal failure induced by gentamicin (GM) nephrotoxicity.", "completion": "{\"entities\": [{\"text\": \"gum Arabic\", \"type\": \"Chemical\"}, {\"text\": \"acute renal failure\", \"type\": \"Disease\"}, {\"text\": \"gentamicin\", \"type\": \"Chemical\"}, {\"text\": \"GM\", \"type\": \"Chemical\"}, {\"text\": \"nephrotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-00183", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Three months later the patient was exposed to a single dose of metoprolol, diltiazem, propafenone (since he had received this drug in the past ), and sparteine (as a probe for the debrisoquine / sparteine type polymorphism of oxidative drug metabolism ). It was found that he was a poor metabolizer of all four drugs, indicating that their metabolism is under the same genetic control.", "completion": "{\"entities\": [{\"text\": \"metoprolol\", \"type\": \"Chemical\"}, {\"text\": \"diltiazem\", \"type\": \"Chemical\"}, {\"text\": \"propafenone\", \"type\": \"Chemical\"}, {\"text\": \"sparteine\", \"type\": \"Chemical\"}, {\"text\": \"debrisoquine\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-00995", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Since the cranial condition precluded use of more usual methods, lidocaine was given intra - arterially, with careful cardiovascular monitoring, to counteract the vasospasm", "completion": "{\"entities\": [{\"text\": \"lidocaine\", \"type\": \"Chemical\"}, {\"text\": \"vasospasm\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02817", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: For each of the three tested calcium channel blockers (diltiazem, verapamil and bepridil) 6 groups of mice were treated by two different doses, i.", "completion": "{\"entities\": [{\"text\": \"calcium\", \"type\": \"Chemical\"}, {\"text\": \"diltiazem\", \"type\": \"Chemical\"}, {\"text\": \"verapamil\", \"type\": \"Chemical\"}, {\"text\": \"bepridil\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01548", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The neurologic evaluation revealed loss of sensation in the saddle area and medial aspect of her right leg.", "completion": "{\"entities\": [{\"text\": \"loss of sensation\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01416", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Risks of the consumption of beverages containing quinine.", "completion": "{\"entities\": [{\"text\": \"quinine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-reassigned-04545", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Among women with cardiovascular disease, long - term use of combined continuous HT significantly increased the risk of venous thromboembolism.", "completion": "{\"entities\": [{\"text\": \"cardiovascular disease\", \"type\": \"Disease\"}, {\"text\": \"venous thromboembolism\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01039", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Further observations on the electrophysiologic effects of oral amiodarone therapy.", "completion": "{\"entities\": [{\"text\": \"amiodarone\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00393", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Heart rate (HR) did not change in either group.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03653", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 ), transverse limb deficiency (AOR = 2.", "completion": "{\"entities\": [{\"text\": \"transverse limb deficiency\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01918", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cerebral infarction with a single oral dose of phenylpropanolamine.", "completion": "{\"entities\": [{\"text\": \"Cerebral infarction\", \"type\": \"Disease\"}, {\"text\": \"phenylpropanolamine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01101", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Skin tests were performed with benzylpenicilloyl-poly-L-lysine (BPO-PLL ), benzylpenicilloate, benzylpenicillin (PG ), ampicillin (AMP ), and AX.", "completion": "{\"entities\": [{\"text\": \"benzylpenicilloyl-poly-L-lysine\", \"type\": \"Chemical\"}, {\"text\": \"BPO-PLL\", \"type\": \"Chemical\"}, {\"text\": \"benzylpenicilloate\", \"type\": \"Chemical\"}, {\"text\": \"benzylpenicillin\", \"type\": \"Chemical\"}, {\"text\": \"PG\", \"type\": \"Chemical\"}, {\"text\": \"ampicillin\", \"type\": \"Chemical\"}, {\"text\": \"AMP\", \"type\": \"Chemical\"}, {\"text\": \"AX\", \"type\": \"Chemical\"}]}", "n_entities": 8}
{"ref": "bc5cdr-train-02533", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This study supports the high frequency of restrictive valve regurgitation in PD patients treated with pergolide and reveals that a significant improvement is usual when the treatment is converted to non - ergot dopamine", "completion": "{\"entities\": [{\"text\": \"valve regurgitation\", \"type\": \"Disease\"}, {\"text\": \"PD\", \"type\": \"Disease\"}, {\"text\": \"pergolide\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00545", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 1 - 10 microg / side ), administered intra - accumbens shell prior to cocaine, dose - dependently attenuated the psychostimulant - induced locomotor hyperactivity.", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"locomotor hyperactivity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01157", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0343) in creatinine clearance was found, but creatinine concentration did not increase significantly compared to controls.", "completion": "{\"entities\": [{\"text\": \"creatinine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04479", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the cohort the cumulative risk of bladder cancer after Wegener's granulomatosis, and the relative prevalence of a history of bladder cancer at the time of diagnosis of Wegener's granulomatosis, were also estimated.", "completion": "{\"entities\": [{\"text\": \"bladder cancer\", \"type\": \"Disease\"}, {\"text\": \"Wegener's granulomatosis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04831", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These results were confirmed by statistical analysis.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02827", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: OBJECTIVES: The United Kingdom Parkinson's Disease Research Group (UKPDRG) trial found an increased mortality in patients with Parkinson's disease (PD) randomized to receive 10 mg selegiline per day and L-dopa compared with those taking L-dopa alone.", "completion": "{\"entities\": [{\"text\": \"Parkinson's Disease\", \"type\": \"Disease\"}, {\"text\": \"PD\", \"type\": \"Disease\"}, {\"text\": \"Parkinson's disease\", \"type\": \"Disease\"}, {\"text\": \"selegiline\", \"type\": \"Chemical\"}, {\"text\": \"L-dopa\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-03383", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Clinical examinations and skin, oral and parenteral challenges with different corticosteroids and ELISA tests were performed.", "completion": "{\"entities\": [{\"text\": \"corticosteroids\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03301", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHOD: In a 6 - week random - assignment, double - blind, placebo - controlled trial (phase A ), haloperidol, 2 - 3 mg / day (standard dose ), and haloperidol, 0.", "completion": "{\"entities\": [{\"text\": \"haloperidol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03121", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The mechanism of chest pain related to cocaine use is discussed and treatment dilemmas are discussed.", "completion": "{\"entities\": [{\"text\": \"chest pain\", \"type\": \"Disease\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00156", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Impotence was more common among male patients than controls and was found to be associated with co - morbidity and the taking of methotrexate.", "completion": "{\"entities\": [{\"text\": \"Impotence\", \"type\": \"Disease\"}, {\"text\": \"methotrexate\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00345", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The present study was undertaken to examine the role of sleep disturbance, induced by clomipramine administration, on the secretory rate of prolactin (PRL) in addition to the direct drug effect.", "completion": "{\"entities\": [{\"text\": \"sleep disturbance\", \"type\": \"Disease\"}, {\"text\": \"clomipramine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01943", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Light microscopic analysis showed a significant protection against ADR - induced cardiac morphological alterations.", "completion": "{\"entities\": [{\"text\": \"ADR\", \"type\": \"Chemical\"}, {\"text\": \"cardiac morphological alterations\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04347", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, a bolus of epinephrine injected through an alternative catheter provoked a hypertensive crisis.", "completion": "{\"entities\": [{\"text\": \"epinephrine\", \"type\": \"Chemical\"}, {\"text\": \"hypertensive\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01360", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pregnant rats were given either vehicle or 2 daily intraperitoneal injections of dexamethasone (0.", "completion": "{\"entities\": [{\"text\": \"dexamethasone\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03637", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Antibacterial medication use during pregnancy and risk of birth defects: National Birth Defects Prevention Study.", "completion": "{\"entities\": [{\"text\": \"birth defects\", \"type\": \"Disease\"}, {\"text\": \"Birth Defects\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01803", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The mean pain score for buffered lidocaine was significantly lower than the mean score for standard lidocaine (2.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"lidocaine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00423", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: An 80 - yr - old man developed acute hepatitis shortly after ingesting oral ceftriaxone.", "completion": "{\"entities\": [{\"text\": \"hepatitis\", \"type\": \"Disease\"}, {\"text\": \"ceftriaxone\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00643", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We retrospectively examined the records of 25 renal transplant patients, who developed or displayed increased proteinuria after SRL conversion.", "completion": "{\"entities\": [{\"text\": \"proteinuria\", \"type\": \"Disease\"}, {\"text\": \"SRL\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-01651", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 3 mg ), while propranolol (0.", "completion": "{\"entities\": [{\"text\": \"propranolol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05028", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Renal plasma flow increased, but albumin excretion and glomerulosclerosis did not change after enalapril treatment.", "completion": "{\"entities\": [{\"text\": \"glomerulosclerosis\", \"type\": \"Disease\"}, {\"text\": \"enalapril\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01097", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: Hypersensitivity myocarditis is a rare and dangerous manifestation of allergy to penicillins", "completion": "{\"entities\": [{\"text\": \"Hypersensitivity myocarditis\", \"type\": \"Disease\"}, {\"text\": \"allergy\", \"type\": \"Disease\"}, {\"text\": \"penicillins\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00016", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The infusion was discontinued either when there was no muscular response to tetanic stimulation of the ulnar nerve or when Sch 120 mg was exceeded.", "completion": "{\"entities\": [{\"text\": \"tetanic\", \"type\": \"Disease\"}, {\"text\": \"Sch\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-02672", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 mg doxorubicin / kg.", "completion": "{\"entities\": [{\"text\": \"doxorubicin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03431", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We used rat models of intrahepatic cholestasis by ethinyl estradiol (EE) treatment and extrahepatic cholestasis by bile duct ligation (BDL) to precisely determine the site of TJ damage.", "completion": "{\"entities\": [{\"text\": \"intrahepatic cholestasis\", \"type\": \"Disease\"}, {\"text\": \"ethinyl estradiol\", \"type\": \"Chemical\"}, {\"text\": \"EE\", \"type\": \"Chemical\"}, {\"text\": \"extrahepatic cholestasis\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04442", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Highest stage reached and latency to each stage were recorded for all mice.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02077", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A transient neurological deficit following intrathecal injection of 1% hyperbaric bupivacaine for unilateral spinal anaesthesia.", "completion": "{\"entities\": [{\"text\": \"neurological deficit\", \"type\": \"Disease\"}, {\"text\": \"bupivacaine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03429", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Recently, several TJ - associated proteins like ZO - 1 and 7H6 have been identified and characterized.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03942", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: High doses of this antibiotic combination should be avoided especially in elderly patients.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-05202", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: By day 45 - 126, at a time when glomerular scarring was present, GLEPP1 was absent from glomerulosclerotic areas although the total glomerular content of GLEPP1 was not different from normal.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02769", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 3 years; range, twelve months to ten years and ten months) who underwent closed reduction of an isolated fracture or dislocation in the emergency department at a level - I trauma center were prospectively evaluated.", "completion": "{\"entities\": [{\"text\": \"fracture\", \"type\": \"Disease\"}, {\"text\": \"dislocation\", \"type\": \"Disease\"}, {\"text\": \"trauma\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03500", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: Reversible inferior colliculus lesions could be considered as the characteristic for metronidazole - induced encephalopathy", "completion": "{\"entities\": [{\"text\": \"inferior colliculus lesions\", \"type\": \"Disease\"}, {\"text\": \"metronidazole\", \"type\": \"Chemical\"}, {\"text\": \"encephalopathy\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03476", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 6 mM (LNa + HCa ). At normal [Na] o, decrease (0.", "completion": "{\"entities\": [{\"text\": \"Na\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02223", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This work evaluates the antinociceptive and constipating effects of the combination of 3.", "completion": "{\"entities\": [{\"text\": \"constipating\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04246", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Hyperkalemia has recently been recognized as a complication of nonsteroidal antiinflammatory agents (NSAID) such as indomethacin.", "completion": "{\"entities\": [{\"text\": \"Hyperkalemia\", \"type\": \"Disease\"}, {\"text\": \"indomethacin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00193", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Saline - pretreated controls given a test dose of morphine (20 mg / kg i.", "completion": "{\"entities\": [{\"text\": \"morphine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05184", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: With either discontinuation or decreased dosage of the drug the symptoms disappeared and did not recur.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00983", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 mm Hg in the SNP group (P less than 0.", "completion": "{\"entities\": [{\"text\": \"SNP\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03207", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The areas where calcitonin is most effective in decreasing locomotor activity are located in the hypothalamus and nucleus accumbens, suggesting that these areas are the major sites of action of calcitonin in inhibiting amphetamine", "completion": "{\"entities\": [{\"text\": \"calcitonin\", \"type\": \"Chemical\"}, {\"text\": \"amphetamine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01665", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thalidomide is an immunomodulatory agent with demonstrated activity in multiple myeloma, mantle cell lymphoma and lymphoplasmacytic lymphoma.", "completion": "{\"entities\": [{\"text\": \"Thalidomide\", \"type\": \"Chemical\"}, {\"text\": \"multiple myeloma\", \"type\": \"Disease\"}, {\"text\": \"mantle cell lymphoma\", \"type\": \"Disease\"}, {\"text\": \"lymphoplasmacytic lymphoma\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02125", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The hemolytic effect of TAM is prevented by low concentrations of alpha-tocopherol (alpha-T) and alpha-tocopherol acetate (alpha-TAc )(inactivated functional hydroxyl) indicating that TAM - induced hemolysis is not related to oxidative membrane damage.", "completion": "{\"entities\": [{\"text\": \"hemolytic\", \"type\": \"Disease\"}, {\"text\": \"TAM\", \"type\": \"Chemical\"}, {\"text\": \"alpha-tocopherol\", \"type\": \"Chemical\"}, {\"text\": \"alpha-T\", \"type\": \"Chemical\"}, {\"text\": \"alpha-tocopherol acetate\", \"type\": \"Chemical\"}, {\"text\": \"alpha-TAc\", \"type\": \"Chemical\"}, {\"text\": \"hydroxyl\", \"type\": \"Chemical\"}, {\"text\": \"hemolysis\", \"type\": \"Disease\"}]}", "n_entities": 8}
{"ref": "bc5cdr-train-04421", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This data suggests that E2 modifies the expression of CD36 at the level of protein expression in monocyte - derived macrophages resulting in reduced cholesteryl ester accumulation following ritonavir", "completion": "{\"entities\": [{\"text\": \"E2\", \"type\": \"Chemical\"}, {\"text\": \"cholesteryl ester\", \"type\": \"Chemical\"}, {\"text\": \"ritonavir\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03766", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In conclusion mitochondrial toxicity is an early common event both in paclitaxel and cisplatin induced neurotoxicity.", "completion": "{\"entities\": [{\"text\": \"mitochondrial toxicity\", \"type\": \"Disease\"}, {\"text\": \"paclitaxel\", \"type\": \"Chemical\"}, {\"text\": \"cisplatin\", \"type\": \"Chemical\"}, {\"text\": \"neurotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00281", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Patients tapped faster after propranolol than diazepam and they were more sedated after diazepam than propranolol.", "completion": "{\"entities\": [{\"text\": \"propranolol\", \"type\": \"Chemical\"}, {\"text\": \"diazepam\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03952", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: o .), whereas Ro4368554 was inactive.", "completion": "{\"entities\": [{\"text\": \"Ro4368554\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02745", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 07 ml / min at 6 months ). Enalapril treatment blunted but did not prevent reduction in GFR in group 4 (0.", "completion": "{\"entities\": [{\"text\": \"Enalapril\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03031", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05 ). The differences in mortality and morbidity between the two groups were not significant.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03173", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This treatment merits further comparison with other cisplatin", "completion": "{\"entities\": [{\"text\": \"cisplatin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02261", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We therefore established sensitive quantification methods and provided a rat ICH model for detection of ICH deterioration.", "completion": "{\"entities\": [{\"text\": \"ICH\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00731", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Similarly, thrombotic risk increased with age and OD values.", "completion": "{\"entities\": [{\"text\": \"thrombotic\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01128", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The possibility that habitual use of acetaminophen alone increases the risk of ESRD", "completion": "{\"entities\": [{\"text\": \"acetaminophen\", \"type\": \"Chemical\"}, {\"text\": \"ESRD\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01163", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Although much has been written about the management of the more common adverse effects of lithium, such as polyuria and tremor, more subtle lithium side effects such as cognitive deficits, loss of creativity, and functional impairments remain understudied.", "completion": "{\"entities\": [{\"text\": \"lithium\", \"type\": \"Chemical\"}, {\"text\": \"polyuria\", \"type\": \"Disease\"}, {\"text\": \"tremor\", \"type\": \"Disease\"}, {\"text\": \"cognitive deficits\", \"type\": \"Disease\"}, {\"text\": \"loss of creativity\", \"type\": \"Disease\"}, {\"text\": \"functional impairments\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-01736", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Moreover, these behaviors are accompanied by biochemical changes in brain regions previously identified as relevant to OCD.", "completion": "{\"entities\": [{\"text\": \"OCD\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00780", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: 272 cases of confusion were reported with valproic acid: 153 women and 119 men.", "completion": "{\"entities\": [{\"text\": \"confusion\", \"type\": \"Disease\"}, {\"text\": \"valproic acid\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02329", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: nAChRs are pentameric ion channels usually composed of alpha and beta subunits.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03752", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSION: When performing intracarotid injection of carboplatin, we must be aware of its potentially blinding ocular toxicity", "completion": "{\"entities\": [{\"text\": \"carboplatin\", \"type\": \"Chemical\"}, {\"text\": \"ocular toxicity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00410", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Increase of Parkinson disability after fluoxetine medication.", "completion": "{\"entities\": [{\"text\": \"Parkinson disability\", \"type\": \"Disease\"}, {\"text\": \"fluoxetine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03777", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A synergistic effect of etoposide and cyclosporin A was observed in a patient with acute T-lymphocytic leukemia in relapse.", "completion": "{\"entities\": [{\"text\": \"etoposide\", \"type\": \"Chemical\"}, {\"text\": \"cyclosporin A\", \"type\": \"Chemical\"}, {\"text\": \"acute T-lymphocytic leukemia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02705", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CASE DESCRIPTION: A 30 - year - old Caucasian woman presented with dental pain, bad breath, and self - reported poor esthetics.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"bad breath\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04444", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The CSS for Chromosomes 10 and 18 progressed to the most severe stages, diverging dramatically from the B6 phenotype.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01206", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 225 mg, for correction of Dupuytren's contracture.", "completion": "{\"entities\": [{\"text\": \"Dupuytren's contracture\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02394", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Secondary outcomes were a postdose SCr increase > or = 25 %, a postdose estimated glomerular filtration rate decrease of > or = 25 %, and the mean peak change in SCr.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04593", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The percentage of vasoconstriction of the right coronary artery was significantly higher than that of the left coronary artery.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02864", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This study tested the hypothesis that activation of nociceptive muscle afferent fibers would be linked to an increased excitability of the human jaw - stretch reflex and whether this process would be sensitive to length and velocity of the stretch.", "completion": "{\"entities\": [{\"text\": \"nociceptive muscle\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01439", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Changes evoked by a single intraperitoneal injection of rilmenidine (600 microg / kg) or alpha-methyldopa (100 mg / kg ), selective I1 - and alpha2 - receptor agonists, respectively, in blood pressure, hemodynamic variability, and locomotor activity were assessed in radiotelemetered sham - operated and ovariectomized (Ovx) Sprague - Dawley female rats with or without 12 - wk estrogen replacement.", "completion": "{\"entities\": [{\"text\": \"rilmenidine\", \"type\": \"Chemical\"}, {\"text\": \"alpha-methyldopa\", \"type\": \"Chemical\"}, {\"text\": \"estrogen\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03195", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Large differences, regarded as statistically significant, between the mexiletine and placebo groups were noted in that end point at months 1 and 4, but only trends were observed at month 12.", "completion": "{\"entities\": [{\"text\": \"mexiletine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00194", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: p .) showed a pronounced rigidity recorded as tonic activity in the electromyogram.", "completion": "{\"entities\": [{\"text\": \"rigidity\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01947", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thirty - six patients were treated with BCNU every 6 to 8 weeks, either by transfemoral catheterization of the internal carotid or vertebral artery or through a fully implantable intracarotid drug delivery system, beginning with a dose of 200 mg / sq m body surface area.", "completion": "{\"entities\": [{\"text\": \"BCNU\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01425", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 mg / kg BW ), anticonvulsant diazepam (2.", "completion": "{\"entities\": [{\"text\": \"diazepam\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00252", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 8 mg / 100 ml) than in control cows (5.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04394", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Although central prolactin actions are thought to contribute to this, the mechanisms are poorly understood.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02872", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Direct comparison between sham and real rTMS effects showed no significant difference in clinician - assessed dyskinesia severity.", "completion": "{\"entities\": [{\"text\": \"dyskinesia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01086", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This change resulted within 2 - 4 weeks in the 50 - 200% increase in the plasma levels of these neuroleptics and the appearance of extrapyramidal symptoms.", "completion": "{\"entities\": [{\"text\": \"extrapyramidal symptoms\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03326", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 01 ), renal interstitial alpha - smooth muscle actin (r = 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02659", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Angiosarcoma of the liver occurred in a 76 - year - old man who had been treated for a well - differentiated adenocarcinoma of the liver with diethylstilbestrol for 13 years.", "completion": "{\"entities\": [{\"text\": \"Angiosarcoma of the liver\", \"type\": \"Disease\"}, {\"text\": \"adenocarcinoma of the liver\", \"type\": \"Disease\"}, {\"text\": \"diethylstilbestrol\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03987", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Lack of teratogenicity was found in piroxicam and DFU - exposed groups.", "completion": "{\"entities\": [{\"text\": \"piroxicam\", \"type\": \"Chemical\"}, {\"text\": \"DFU\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02945", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The purpose of this study was to determine if changes occur in this tonotopic organization following cochlear hearing loss.", "completion": "{\"entities\": [{\"text\": \"hearing loss\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04717", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Before angiography, intradermal or intravenous indocyanine green testing, or both was performed at 13 of 15 institutions.", "completion": "{\"entities\": [{\"text\": \"indocyanine green\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00807", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: From January 1986 to January 2009, 1223 consecutive ALF patients were evaluated: ATT alone was the cause in 70 (5.", "completion": "{\"entities\": [{\"text\": \"ALF\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00520", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 (95 percent confidence interval, 1.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04082", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In vivo microdialysis demonstrated that an intraperitoneal administration of pilocarpine induced a pronounced increment of hippocampal glutamate and aspartate whereas no significant change was observed on the level of glycine and GABA.", "completion": "{\"entities\": [{\"text\": \"pilocarpine\", \"type\": \"Chemical\"}, {\"text\": \"glutamate\", \"type\": \"Chemical\"}, {\"text\": \"aspartate\", \"type\": \"Chemical\"}, {\"text\": \"glycine\", \"type\": \"Chemical\"}, {\"text\": \"GABA\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-04794", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Memory retrieval of experiences acquired prior to cocaine administration was impaired and negatively correlated with NFkappaB activity in the frontal cortex.", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05219", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Apomorphine, a nonselective dopamine agonist, was selected due to its biphasic behavioral effects, its ability to induce hypothermia, and to produce distinct changes to dopamine turnover in the rodent brain.", "completion": "{\"entities\": [{\"text\": \"Apomorphine\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}, {\"text\": \"dopamine agonist\", \"type\": \"Chemical\"}, {\"text\": \"hypothermia\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03332", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05 ), glomerular alpha - smooth muscle actin (r = 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02019", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This article reports the changes in gallbladder function examined by ultrasonography in 20 Chinese patients with active acromegaly treated with sc injection of the somatostatin analog octreotide in dosages of 300 - 1500 micrograms / day for a mean of 24.", "completion": "{\"entities\": [{\"text\": \"acromegaly\", \"type\": \"Disease\"}, {\"text\": \"octreotide\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02299", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 days, increasing cost ); sex, diagnosis or medical co - morbidity, and daily clozapine dose, which fell with age, were unrelated.", "completion": "{\"entities\": [{\"text\": \"clozapine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01987", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After 3 days of combined treatment, a marked elevation in plasma and tissue lithium levels accompanied a reduction in water intake.", "completion": "{\"entities\": [{\"text\": \"lithium\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02258", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: Sub - chronic low dose GVG potentiates and extends the inhibition of cocaine - induced increases in dopamine", "completion": "{\"entities\": [{\"text\": \"GVG\", \"type\": \"Chemical\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04754", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Optimal control of the absences was achieved with sodium valproate, lamotrigine, or ethosuximide", "completion": "{\"entities\": [{\"text\": \"sodium valproate\", \"type\": \"Chemical\"}, {\"text\": \"lamotrigine\", \"type\": \"Chemical\"}, {\"text\": \"ethosuximide\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00080", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Although paralysis after magnesium administration has been described in patients with known myasthenia gravis, it has not previously been reported to be the initial or only manifestation of the disease.", "completion": "{\"entities\": [{\"text\": \"paralysis\", \"type\": \"Disease\"}, {\"text\": \"magnesium\", \"type\": \"Chemical\"}, {\"text\": \"myasthenia gravis\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-reassigned-02674", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 mg doxorubicin / kg.", "completion": "{\"entities\": [{\"text\": \"doxorubicin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00693", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: The mean +/- SD duration of BZD / RD use was 7 +/- 7 years (range 1 - 31 ). Two or three BZDs / RDs were concomitantly taken by 26% of users (n = 20 ). Long - term use of these drugs was associated with female sex and use of a higher number of drugs with effects on the CNS, which tended to be related to diagnosed dementia.", "completion": "{\"entities\": [{\"text\": \"BZDs\", \"type\": \"Chemical\"}, {\"text\": \"dementia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01496", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Current protein - based technology offers a new therapeutic venue by which antibodies bind the drug in the blood stream, inactivating its toxic effects.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03949", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Although the underlying mechanism (s) are not well understood, these effects may involve an increase in acetylcholine (ACh) levels.", "completion": "{\"entities\": [{\"text\": \"acetylcholine\", \"type\": \"Chemical\"}, {\"text\": \"ACh\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02049", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Macula toxicity after intravitreal amikacin.", "completion": "{\"entities\": [{\"text\": \"toxicity\", \"type\": \"Disease\"}, {\"text\": \"amikacin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02631", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Across all groups, no more than 5% of patients had clinically significant weight change.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00246", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In patients with cardiomegaly, the increase in heart size was similar in both groups.", "completion": "{\"entities\": [{\"text\": \"cardiomegaly\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03291", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 99mTc-glucarate was easy to prepare, stable for 96 h and was used to study its biodistribution in rats with isoproterenol - induced acute myocardial infarction.", "completion": "{\"entities\": [{\"text\": \"99mTc-glucarate\", \"type\": \"Chemical\"}, {\"text\": \"isoproterenol\", \"type\": \"Chemical\"}, {\"text\": \"myocardial infarction\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02753", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: patients undergoing electroconvulsive therapy (ECT) often receive succinylcholine as part of the anesthetic procedure.", "completion": "{\"entities\": [{\"text\": \"succinylcholine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00917", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHOD: This was a cross - sectional study of 85 patients from a lithium clinic who received different dose schedules.", "completion": "{\"entities\": [{\"text\": \"lithium\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00160", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The risk of renal papillary necrosis was increased nearly 20 - fold by consumption of phenacetin, which also increased the risk for cancer of the renal pelvis and bladder but not for ureteric cancer.", "completion": "{\"entities\": [{\"text\": \"renal papillary necrosis\", \"type\": \"Disease\"}, {\"text\": \"phenacetin\", \"type\": \"Chemical\"}, {\"text\": \"cancer of the renal pelvis and bladder\", \"type\": \"Disease\"}, {\"text\": \"ureteric cancer\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01191", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The Li - treated rats produced a large volume of hypotonic urine with low ionic concentrations.", "completion": "{\"entities\": [{\"text\": \"Li\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-reassigned-01497", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Central action of narcotic analgesics.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04772", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A positive weight response was seen in 16% of patients.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04944", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Endocrine therapy consisted of testosterone heptylate or human chorionic gonadotropin for hypogonadism and bromocriptine for hyperprolactinemia.", "completion": "{\"entities\": [{\"text\": \"testosterone heptylate\", \"type\": \"Chemical\"}, {\"text\": \"hypogonadism\", \"type\": \"Disease\"}, {\"text\": \"bromocriptine\", \"type\": \"Chemical\"}, {\"text\": \"hyperprolactinemia\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04487", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSION: The results indicate a dose - response relationship between cyclophosphamide and the risk of bladder cancer, high cumulative risks in the entire cohort, and also the possibility of risk factors operating even before Wegener's granulomatosis", "completion": "{\"entities\": [{\"text\": \"cyclophosphamide\", \"type\": \"Chemical\"}, {\"text\": \"bladder cancer\", \"type\": \"Disease\"}, {\"text\": \"Wegener's granulomatosis\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04482", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0, 95% confidence interval (CI) 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02221", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This may have been a side effect of citalopram", "completion": "{\"entities\": [{\"text\": \"citalopram\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01184", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Major toxicities were cardiotoxicity and leukopenia.", "completion": "{\"entities\": [{\"text\": \"toxicities\", \"type\": \"Disease\"}, {\"text\": \"cardiotoxicity\", \"type\": \"Disease\"}, {\"text\": \"leukopenia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04206", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This is the first reported case of sinus arrest associated with continuous - infusion cimetidine", "completion": "{\"entities\": [{\"text\": \"sinus arrest\", \"type\": \"Disease\"}, {\"text\": \"cimetidine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03909", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Findings suggest a potential for H (3 )- receptor antagonists in improving the refractory cases of schizophrenia", "completion": "{\"entities\": [{\"text\": \"schizophrenia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03298", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The high image quality suggests that high contrast images can be obtained in humans and the 96 h stability makes it an ideal agent to detect, in patients, early cardiac infarction", "completion": "{\"entities\": [{\"text\": \"cardiac infarction\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01169", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: For previously treated advanced breast cancer, there is no standard second - line therapy.", "completion": "{\"entities\": [{\"text\": \"breast cancer\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-reassigned-03827", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Levodopa - induced ocular dyskinesias in Parkinson's disease.", "completion": "{\"entities\": [{\"text\": \"Levodopa\", \"type\": \"Chemical\"}, {\"text\": \"ocular dyskinesias\", \"type\": \"Disease\"}, {\"text\": \"Parkinson's disease\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02509", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Valvular heart disease in patients with Parkinson's disease treated with pergolide.", "completion": "{\"entities\": [{\"text\": \"Valvular heart disease\", \"type\": \"Disease\"}, {\"text\": \"Parkinson's disease\", \"type\": \"Disease\"}, {\"text\": \"pergolide\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02014", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05) or without (pH 4.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03070", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The symptom was treated successfully with trihexyphenidyl anticholinergic therapy.", "completion": "{\"entities\": [{\"text\": \"trihexyphenidyl\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01074", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: There was no correlation between vitamin B12 or folate levels and development of myelosuppression.", "completion": "{\"entities\": [{\"text\": \"vitamin B12\", \"type\": \"Chemical\"}, {\"text\": \"folate\", \"type\": \"Chemical\"}, {\"text\": \"myelosuppression\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01991", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Controlled study in agoraphobia with panic disorder.", "completion": "{\"entities\": [{\"text\": \"agoraphobia\", \"type\": \"Disease\"}, {\"text\": \"panic disorder\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02800", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Uni - and multivariate analyses were used to test the influence of the clinical variables: age, sex, stroke, myocardiopathy (MP ), duration of the test, mitral regurgitation (MR) and the MZ dose.", "completion": "{\"entities\": [{\"text\": \"stroke\", \"type\": \"Disease\"}, {\"text\": \"myocardiopathy\", \"type\": \"Disease\"}, {\"text\": \"MP\", \"type\": \"Disease\"}, {\"text\": \"mitral regurgitation\", \"type\": \"Disease\"}, {\"text\": \"MR\", \"type\": \"Disease\"}, {\"text\": \"MZ\", \"type\": \"Chemical\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-00511", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After 10 days, only ANF was elevated, and only in the TG + HAART cohort.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00754", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 ml / kg of corn oil containing vitamin D2 and cholesterol to induce atherosclerosis.", "completion": "{\"entities\": [{\"text\": \"vitamin D2\", \"type\": \"Chemical\"}, {\"text\": \"cholesterol\", \"type\": \"Chemical\"}, {\"text\": \"atherosclerosis\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04410", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Furthermore, peripheral blood monocytes isolated from ritonavir - treated females had less cholesteryl ester accumulation.", "completion": "{\"entities\": [{\"text\": \"ritonavir\", \"type\": \"Chemical\"}, {\"text\": \"cholesteryl ester\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03585", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The onset of all manifestations (except toxic encephalopathy) was usually subacute, with subsequent partial recovery.", "completion": "{\"entities\": [{\"text\": \"encephalopathy\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02726", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Groups 1 and 3 remained untreated while groups 2 and 4 received enalapril.", "completion": "{\"entities\": [{\"text\": \"enalapril\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00790", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Neuroimage 40, 1328 - 1339 ). Ecstasy users performed significantly worse in learning and memory compared to controls and cannabis users.", "completion": "{\"entities\": [{\"text\": \"Ecstasy\", \"type\": \"Chemical\"}, {\"text\": \"cannabis\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02430", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Warfarin is the most widely used oral anticoagulant and is indicated for many clinical conditions.", "completion": "{\"entities\": [{\"text\": \"Warfarin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03428", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Although hepatocyte TJs are impaired in cholestasis, attempts to localize the precise site of hepatocyte TJ damage by freeze - fracture electron microscopy have produced limited information.", "completion": "{\"entities\": [{\"text\": \"cholestasis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03870", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We describe a 15 - yr - old girl who had orthotopic liver transplantation because of Wilson's disease.", "completion": "{\"entities\": [{\"text\": \"Wilson's disease\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05009", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Flestolol (ACC-9089) is a nonselective, competitive, ultra - short - acting beta - adrenergic blocking agent, without any intrinsic sympathomimetic activity.", "completion": "{\"entities\": [{\"text\": \"Flestolol\", \"type\": \"Chemical\"}, {\"text\": \"ACC-9089\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02919", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Preparations containing lindane continue to be sold over the counter and may represent a hazard to poorly informed patients.", "completion": "{\"entities\": [{\"text\": \"lindane\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02308", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Noxious chemical stimulation of rat facial mucosa increases intracranial blood flow through a trigemino - parasympathetic reflex -- an experimental model for vascular dysfunctions in cluster headache.", "completion": "{\"entities\": [{\"text\": \"vascular dysfunctions\", \"type\": \"Disease\"}, {\"text\": \"cluster headache\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01327", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 %(13 / 50) had akathisia compared with 32.", "completion": "{\"entities\": [{\"text\": \"akathisia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02355", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cerebral vasculitis following oral methylphenidate intake in an adult: a case report.", "completion": "{\"entities\": [{\"text\": \"Cerebral vasculitis\", \"type\": \"Disease\"}, {\"text\": \"methylphenidate\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00146", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The multiple drug schema consisted of: Etoposide 16.", "completion": "{\"entities\": [{\"text\": \"Etoposide\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03600", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thus, FS containing 47.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02196", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: During these two episodes, his blood pressure diminished but no severe hypotension was noted.", "completion": "{\"entities\": [{\"text\": \"hypotension\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03947", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The selective 5 - HT6 receptor antagonist Ro4368554 restores memory performance in cholinergic and serotonergic models of memory deficiency in the rat.", "completion": "{\"entities\": [{\"text\": \"Ro4368554\", \"type\": \"Chemical\"}, {\"text\": \"memory deficiency\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04386", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: mToR inhibitors - induced proteinuria: mechanisms, significance, and management.", "completion": "{\"entities\": [{\"text\": \"proteinuria\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05114", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cancer patients who are chronic carriers of HBV have a higher hepatic complication rate while receiving cytotoxic chemotherapy (CT) and this has mainly been attributed to HBV reactivation.", "completion": "{\"entities\": [{\"text\": \"Cancer\", \"type\": \"Disease\"}, {\"text\": \"hepatic complication\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02969", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: m ., respectively, 1 week later.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03775", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Preliminary studies suggest that statins", "completion": "{\"entities\": [{\"text\": \"statins\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02550", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Recommendations to avoid potential cranial nerve deficits from papaverine", "completion": "{\"entities\": [{\"text\": \"cranial nerve deficits\", \"type\": \"Disease\"}, {\"text\": \"papaverine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04472", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In contrast, reports of myocardial dysfunction due to acute iatrogenic overdose are rare.", "completion": "{\"entities\": [{\"text\": \"myocardial dysfunction\", \"type\": \"Disease\"}, {\"text\": \"overdose\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04104", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It has been associated with infrequent and usually reversible severe hepatic dysfunction.", "completion": "{\"entities\": [{\"text\": \"hepatic dysfunction\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-reassigned-04622", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: v .) preceded by monoHER (500 mg / kg i.", "completion": "{\"entities\": [{\"text\": \"monoHER\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02276", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: SE was induced 20 h following the second injection and terminated 3 h later.", "completion": "{\"entities\": [{\"text\": \"SE\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00011", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A dose - response study.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01768", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 001 vs control ). These results suggest that betaxolol could be less of a depression - inducer than timolol", "completion": "{\"entities\": [{\"text\": \"betaxolol\", \"type\": \"Chemical\"}, {\"text\": \"depression\", \"type\": \"Disease\"}, {\"text\": \"timolol\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04514", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Among the 5 patients with white matter abnormalities, 4 patients (80.", "completion": "{\"entities\": [{\"text\": \"white matter abnormalities\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03455", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: To assess the safety of the ACE inhibitor enalapril a multicenter, randomized, prazosin - controlled trial was designed that compared the incidence and severity of symptomatic hypotension on the first day of treatment.", "completion": "{\"entities\": [{\"text\": \"ACE inhibitor\", \"type\": \"Chemical\"}, {\"text\": \"enalapril\", \"type\": \"Chemical\"}, {\"text\": \"prazosin\", \"type\": \"Chemical\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02103", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0001 ). Five patients died before the interview, all of them had taken appetite suppressants.", "completion": "{\"entities\": [{\"text\": \"appetite suppressants\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02867", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The normalized reflex amplitude increased with an increase in velocity at a given displacement, but remained constant with different displacements at a given velocity.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00153", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Sexual dysfunction among patients with arthritis.", "completion": "{\"entities\": [{\"text\": \"Sexual dysfunction\", \"type\": \"Disease\"}, {\"text\": \"arthritis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05163", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After the treatments and behavioral observation, glutamate uptake by segments of the brain was analyzed.", "completion": "{\"entities\": [{\"text\": \"glutamate\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03715", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The dose - limiting toxic effect was transient noncumulative granulocytopenia.", "completion": "{\"entities\": [{\"text\": \"granulocytopenia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04940", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Every patient was screened for testosterone and 451 were screened for prolactin on the basis of low sexual desire, gynecomastia or testosterone less than 4 ng ./ ml.", "completion": "{\"entities\": [{\"text\": \"testosterone\", \"type\": \"Chemical\"}, {\"text\": \"low sexual desire\", \"type\": \"Disease\"}, {\"text\": \"gynecomastia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00127", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The CBZ levels measured in plasma and brain of these animals, however, were below those normally considered protective.", "completion": "{\"entities\": [{\"text\": \"CBZ\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04027", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Paracetamol - associated coma, metabolic acidosis, renal and hepatic failure.", "completion": "{\"entities\": [{\"text\": \"Paracetamol\", \"type\": \"Chemical\"}, {\"text\": \"coma\", \"type\": \"Disease\"}, {\"text\": \"metabolic acidosis\", \"type\": \"Disease\"}, {\"text\": \"renal and hepatic failure\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03384", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the two patients, skin and ELISA tests with paramethasone were negative, as was the prick test with each of its excipients.", "completion": "{\"entities\": [{\"text\": \"paramethasone\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04543", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These findings suggest that overgrowth of the exencephalic neural tissue causes the altered distribution patterns of vessels, subsequent peripheral circulatory failure and / or hemorrhaging in various parts of the exencephalic head, leading to the multiple modes of tissue reduction during transformation from exencephaly to anencephaly", "completion": "{\"entities\": [{\"text\": \"exencephalic\", \"type\": \"Disease\"}, {\"text\": \"circulatory failure\", \"type\": \"Disease\"}, {\"text\": \"hemorrhaging\", \"type\": \"Disease\"}, {\"text\": \"exencephaly\", \"type\": \"Disease\"}, {\"text\": \"anencephaly\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-04105", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Based on a score of 8 on the Naranjo adverse drug reaction probability scale, telithromycin was the probable cause of acute hepatitis in this patient, and pathological findings suggested drug - induced toxic hepatitis.", "completion": "{\"entities\": [{\"text\": \"adverse drug reaction\", \"type\": \"Disease\"}, {\"text\": \"telithromycin\", \"type\": \"Chemical\"}, {\"text\": \"hepatitis\", \"type\": \"Disease\"}, {\"text\": \"toxic hepatitis\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01119", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We report a case of atracurium - related paralysis", "completion": "{\"entities\": [{\"text\": \"atracurium\", \"type\": \"Chemical\"}, {\"text\": \"paralysis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04796", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These results provide evidence for a possible mechanistic role of oxidative and nitrosative stress and NFkappaB in the alterations induced by cocaine.", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03477", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 675 mM) or increase (3.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01299", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Four compounds known to increase QT interval and cause TDP were investigated: terfenadine, terodiline, cisapride and E4031.", "completion": "{\"entities\": [{\"text\": \"TDP\", \"type\": \"Disease\"}, {\"text\": \"terfenadine\", \"type\": \"Chemical\"}, {\"text\": \"terodiline\", \"type\": \"Chemical\"}, {\"text\": \"cisapride\", \"type\": \"Chemical\"}, {\"text\": \"E4031\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-00751", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The aim of this study is to examine the role of gastric acid back - diffusion, mast cell histamine release, lipid peroxide (LPO) generation and mucosal microvascular permeability in modulating gastric hemorrhage and ulcer in rats with atherosclerosis induced by coadministration of vitamin D2 and cholesterol.", "completion": "{\"entities\": [{\"text\": \"histamine\", \"type\": \"Chemical\"}, {\"text\": \"gastric hemorrhage\", \"type\": \"Disease\"}, {\"text\": \"ulcer\", \"type\": \"Disease\"}, {\"text\": \"atherosclerosis\", \"type\": \"Disease\"}, {\"text\": \"vitamin D2\", \"type\": \"Chemical\"}, {\"text\": \"cholesterol\", \"type\": \"Chemical\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-00405", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Focal injury in the cortex was produced by infusion of lactate at acid pH or by stab caused by needle insertion.", "completion": "{\"entities\": [{\"text\": \"injury in the cortex\", \"type\": \"Disease\"}, {\"text\": \"lactate\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02611", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Compared with placebo, modafinil decreased nighttime sleep latency and increased slow - wave sleep time in cocaine - dependent participants.", "completion": "{\"entities\": [{\"text\": \"modafinil\", \"type\": \"Chemical\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01939", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Studies dealing with myocardial infarction", "completion": "{\"entities\": [{\"text\": \"myocardial infarction\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01147", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We conclude that in streptozotocin - diabetic rats with an increased urinary albumin excretion, a reduced heparan sulphate", "completion": "{\"entities\": [{\"text\": \"streptozotocin\", \"type\": \"Chemical\"}, {\"text\": \"diabetic\", \"type\": \"Disease\"}, {\"text\": \"heparan sulphate\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04429", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: TR (-) rats exhibited a significant up - regulation of Pgp in brain capillary endothelial cells compared with wild - type controls.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01297", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: terfenadine and terodiline ). 2.", "completion": "{\"entities\": [{\"text\": \"terfenadine\", \"type\": \"Chemical\"}, {\"text\": \"terodiline\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04232", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The spinal cords of the animals that received bupivacaine", "completion": "{\"entities\": [{\"text\": \"bupivacaine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02765", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Ketamine sedation for the reduction of children' s fractures in the emergency department.", "completion": "{\"entities\": [{\"text\": \"Ketamine\", \"type\": \"Chemical\"}, {\"text\": \"fractures\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00034", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Lithium also caused proteinuria and systolic hypertension in absence of glomerulosclerosis.", "completion": "{\"entities\": [{\"text\": \"Lithium\", \"type\": \"Chemical\"}, {\"text\": \"proteinuria\", \"type\": \"Disease\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}, {\"text\": \"glomerulosclerosis\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00207", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, compression neuropathy due to fibrotic muscle affected by pentazocine - induced myopathy has not previously been reported.", "completion": "{\"entities\": [{\"text\": \"compression neuropathy\", \"type\": \"Disease\"}, {\"text\": \"pentazocine\", \"type\": \"Chemical\"}, {\"text\": \"myopathy\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02427", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We found that maltolyl p-coumarate significantly decreased apoptotic cell death and reduced reactive oxygen species, cytochrome c release, and caspase 3 activation.", "completion": "{\"entities\": [{\"text\": \"maltolyl p-coumarate\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00334", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Time course of lipid peroxidation in puromycin aminonucleoside - induced nephropathy.", "completion": "{\"entities\": [{\"text\": \"puromycin aminonucleoside\", \"type\": \"Chemical\"}, {\"text\": \"nephropathy\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02407", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 11 ), whereas SCr increases > or = 25% were 10.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04395", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We first tested whether chronic hyperprolactinemia inhibited two neuroendocrine parameters necessary for female fertility: pulsatile LH secretion and the estrogen - induced LH surge.", "completion": "{\"entities\": [{\"text\": \"hyperprolactinemia\", \"type\": \"Disease\"}, {\"text\": \"estrogen\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03953", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Both, Ro4368554 (3 and 10 mg / kg, intraperitoneally (i.", "completion": "{\"entities\": [{\"text\": \"Ro4368554\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02108", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Choreoathetoid movements associated with rapid adjustment to methadone.", "completion": "{\"entities\": [{\"text\": \"Choreoathetoid movements\", \"type\": \"Disease\"}, {\"text\": \"methadone\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00417", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, acetaminophen has been demonstrated to produce symptoms of anaphylaxis, including hypotension, in sensitive individuals.", "completion": "{\"entities\": [{\"text\": \"acetaminophen\", \"type\": \"Chemical\"}, {\"text\": \"anaphylaxis\", \"type\": \"Disease\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03068", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Here we present a case of withdrawal-emergent RS, which is the first of its kind to be reported.", "completion": "{\"entities\": [{\"text\": \"withdrawal-emergent RS\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02946", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Under anesthesia, the superior temporal gyrus of adult macaque monkeys was exposed, and the tonotopic organization of A1 was mapped using conventional microelectrode recording techniques.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00606", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Intracerebroventricular injection of U-II also caused an increase in: food intake at doses of 100 and 1, 000 ng / mouse, water intake at doses of 100 - 10, 000 ng / mouse, and horizontal locomotion activity at a dose of 10, 000 ng / mouse.", "completion": "{\"entities\": [{\"text\": \"U-II\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05216", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These results suggest that the facilitation of memory retrieval by pre - test morphine might be the direct action of morphine", "completion": "{\"entities\": [{\"text\": \"morphine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01034", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A case of tardive dyskinesia caused by metoclopramide.", "completion": "{\"entities\": [{\"text\": \"tardive dyskinesia\", \"type\": \"Disease\"}, {\"text\": \"metoclopramide\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04676", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Both active treatments were well tolerated.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00824", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Compared with hepatitis E virus (HEV) and non - A non - E - induced ALF, ATT - ALF patients had nearly similar presentations except for older age and less elevation of liver enzymes.", "completion": "{\"entities\": [{\"text\": \"hepatitis E\", \"type\": \"Disease\"}, {\"text\": \"ALF\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01373", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 20 [95% confidence interval (CI) 1.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01047", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In view of the known tendency of busulfan to induce cellular atypia and carcinoma", "completion": "{\"entities\": [{\"text\": \"busulfan\", \"type\": \"Chemical\"}, {\"text\": \"carcinoma\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04017", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Inflammatory cells are postulated to mediate some of the brain damage following ischemic stroke.", "completion": "{\"entities\": [{\"text\": \"brain damage\", \"type\": \"Disease\"}, {\"text\": \"ischemic stroke\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02710", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thyroxine abuse: an unusual case of thyrotoxicosis in pregnancy.", "completion": "{\"entities\": [{\"text\": \"Thyroxine\", \"type\": \"Chemical\"}, {\"text\": \"thyrotoxicosis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00529", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Among women who used oral contraceptives, the odds ratio was 2.", "completion": "{\"entities\": [{\"text\": \"oral contraceptives\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04663", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 001 ), rizatriptan being superior within 1 h of treatment.", "completion": "{\"entities\": [{\"text\": \"rizatriptan\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04575", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The locomotor activity was decreased from corresponding controls in all strains studied, except for the ICR mice, during an overnight drug - free period following the fourth amantadine treatment.", "completion": "{\"entities\": [{\"text\": \"amantadine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03935", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Anticoagulant - induced femoral nerve palsy represents the most common form of warfarin - induced peripheral neuropathy; it is characterized by severe pain in the inguinal region, varying degrees of motor and sensory impairment, and flexure contracture", "completion": "{\"entities\": [{\"text\": \"femoral nerve palsy\", \"type\": \"Disease\"}, {\"text\": \"warfarin\", \"type\": \"Chemical\"}, {\"text\": \"peripheral neuropathy\", \"type\": \"Disease\"}, {\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"motor and sensory impairment\", \"type\": \"Disease\"}, {\"text\": \"contracture\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-reassigned-05475", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 6 (stratum 1) and 2.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-05197", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 005 ). This occurred in association with an increase in urinary protein content from 1.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03631", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The plasma levels of atrial natriuretic peptide (ANP) and BNP were measured at the time of radionuclide angiography.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01350", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Hippocampal ACh also was measured during testing for handling - induced convulsions.", "completion": "{\"entities\": [{\"text\": \"ACh\", \"type\": \"Chemical\"}, {\"text\": \"convulsions\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03055", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The goal of this study was to determine the role of synthesis / release of bradykinin to activate B2 receptors in disruption of the blood - brain barrier during acute hypertension.", "completion": "{\"entities\": [{\"text\": \"bradykinin\", \"type\": \"Chemical\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02282", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Delirium during clozapine treatment: incidence and associated risk factors.", "completion": "{\"entities\": [{\"text\": \"Delirium\", \"type\": \"Disease\"}, {\"text\": \"clozapine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04350", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Long - term glutamate supplementation failed to protect against peripheral neurotoxicity of paclitaxel.", "completion": "{\"entities\": [{\"text\": \"glutamate\", \"type\": \"Chemical\"}, {\"text\": \"peripheral neurotoxicity\", \"type\": \"Disease\"}, {\"text\": \"paclitaxel\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03315", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Therefore, we studied the predictive effect of renal ACE activity for the severity of renal damage induced by a single injection of adriamycin in rats.", "completion": "{\"entities\": [{\"text\": \"renal damage\", \"type\": \"Disease\"}, {\"text\": \"adriamycin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00827", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 9 %) patients recovered with medical treatment.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04824", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Picloxydine irrigations appeared to have a lower incidence of erosive cystitis", "completion": "{\"entities\": [{\"text\": \"Picloxydine\", \"type\": \"Chemical\"}, {\"text\": \"cystitis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00892", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Whereas certain in vivo data suggest that these effects are alpha - mediated, other in vitro data suggest the opposite.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03175", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We prospectively evaluated the adverse reactions of apraclonidine in 20 normal volunteers by instilling a single drop of 1% apraclonidine in their right eyes.", "completion": "{\"entities\": [{\"text\": \"apraclonidine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03270", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: o ., Ato could prevent endothelial NO synthase (eNOS) downregulation and the increase in O2- in Sprague - Dawley (SD) rats, thereby reducing blood pressure.", "completion": "{\"entities\": [{\"text\": \"Ato\", \"type\": \"Chemical\"}, {\"text\": \"NO\", \"type\": \"Chemical\"}, {\"text\": \"O2-\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00553", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: T - cell stimulation by therapeutic concentration of ticlopidine was demonstrated in vitro in the patients, but not in healthy controls.", "completion": "{\"entities\": [{\"text\": \"ticlopidine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01410", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 01 ). The development of severe CAB - induced anemia in prostate cancer patients did not correlate with T baseline values (T < 3 ng / ml versus T > or = 3 ng / ml ), with age (< 76 yrs versus > or = 76 yrs ), and clinical stage (stage C versus stage D1 ). Severe and clinically evident anemia was easily corrected by subcutaneous injections (3 times / week for 1 month) of recombinant erythropoietin (rHuEPO - beta ). CONCLUSION: Our data suggest that rHuEPO - beta correctable CAB - induced anemia occurs in 14.", "completion": "{\"entities\": [{\"text\": \"anemia\", \"type\": \"Disease\"}, {\"text\": \"prostate cancer\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01023", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Three infants, born of two mothers with inflammatory bowel disease who received treatment with sulphasalazine throughout pregnancy, were found to have major congenital anomalies.", "completion": "{\"entities\": [{\"text\": \"inflammatory bowel disease\", \"type\": \"Disease\"}, {\"text\": \"sulphasalazine\", \"type\": \"Chemical\"}, {\"text\": \"congenital anomalies\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00771", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: 3MA significantly improved cardiac function and reduced mitochondrial injury.", "completion": "{\"entities\": [{\"text\": \"3MA\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04638", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Respiratory insufficiency was further worsened by Proteus mirabilis infection and severe bronchoconstriction.", "completion": "{\"entities\": [{\"text\": \"Respiratory insufficiency\", \"type\": \"Disease\"}, {\"text\": \"Proteus mirabilis infection\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01905", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In those with symptoms of hearing loss, the drug should be stopped for four weeks, and when the audiogram is stable or improved, therapy should be restarted at 10 to 25 mg / kg per dose.", "completion": "{\"entities\": [{\"text\": \"hearing loss\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04180", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05 ). CONCLUSIONS: Prilocaine may be preferable to lidocaine for short surgical procedures because it has a similar duration of action but a lower incidence of TNSs", "completion": "{\"entities\": [{\"text\": \"Prilocaine\", \"type\": \"Chemical\"}, {\"text\": \"lidocaine\", \"type\": \"Chemical\"}, {\"text\": \"TNSs\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03582", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This was most frequently found in children, many of whom had received clioquinol as treatment for acrodermatitis enteropathica.", "completion": "{\"entities\": [{\"text\": \"clioquinol\", \"type\": \"Chemical\"}, {\"text\": \"acrodermatitis enteropathica\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03196", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These differences were observed even though the serum mexiletine levels obtained in this study were generally lower than those observed in studies that have used the regular form of the drug.", "completion": "{\"entities\": [{\"text\": \"mexiletine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01539", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: OBJECTIVE: Conventional treatment methods of lumbusacral radiculopathy are physical therapy, epidural steroid injections, oral medications, and spinal manipulative therapy.", "completion": "{\"entities\": [{\"text\": \"radiculopathy\", \"type\": \"Disease\"}, {\"text\": \"steroid\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00616", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Abnormal brain responses to somatosensory stimuli have been found in patients with hyperalgesia as well as in normal subjects during experimental central sensitization.", "completion": "{\"entities\": [{\"text\": \"hyperalgesia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04282", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Two patients with similar clinical features are presented: both patients had chronic renal failure, on hemodialysis for many years but recently begun on a high - flux dialyzer; both had been receiving a carbidopa/levodopa preparation; and both had the onset of hallucinosis and recurrent seizures, which were refractory to anticonvulsants.", "completion": "{\"entities\": [{\"text\": \"chronic renal failure\", \"type\": \"Disease\"}, {\"text\": \"carbidopa/levodopa\", \"type\": \"Chemical\"}, {\"text\": \"hallucinosis\", \"type\": \"Disease\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03868", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Renal Fanconi syndrome and myopathy after liver transplantation: drug - related mitochondrial cytopathy ? Advances in the field of transplantation provide a better quality of life and allow more favorable conditions for growth and development in children.", "completion": "{\"entities\": [{\"text\": \"Renal Fanconi syndrome\", \"type\": \"Disease\"}, {\"text\": \"myopathy\", \"type\": \"Disease\"}, {\"text\": \"mitochondrial cytopathy\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04123", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: Patients receiving an OLTX only from June 1985 through December of 1994 who survived 6 months postoperatively were studied (n = 834 ). Our prospectively collected database was the source of information.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01433", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: When CPA, diazepam or 2PAM was given immediately after DFP - atropine, these treatments prevented, delayed or shortened the occurrence of serious signs of poisoning.", "completion": "{\"entities\": [{\"text\": \"CPA\", \"type\": \"Chemical\"}, {\"text\": \"diazepam\", \"type\": \"Chemical\"}, {\"text\": \"2PAM\", \"type\": \"Chemical\"}, {\"text\": \"DFP\", \"type\": \"Chemical\"}, {\"text\": \"atropine\", \"type\": \"Chemical\"}, {\"text\": \"poisoning\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-03347", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Five of 33 (15 %) of the tobramycin - treated patients and 16 of 29 (55.", "completion": "{\"entities\": [{\"text\": \"tobramycin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01403", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 3 %). This CAB - induced anemia was normochromic and normocytic.", "completion": "{\"entities\": [{\"text\": \"anemia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00485", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: bipolar II ), number of previous manic episodes, type of antidepressant therapy used (electroconvulsive therapy vs.", "completion": "{\"entities\": [{\"text\": \"bipolar II\", \"type\": \"Disease\"}, {\"text\": \"manic\", \"type\": \"Disease\"}, {\"text\": \"antidepressant\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02992", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Sublingual absorption of the quaternary ammonium antiarrhythmic agent, UM-272.", "completion": "{\"entities\": [{\"text\": \"quaternary ammonium\", \"type\": \"Chemical\"}, {\"text\": \"UM-272\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00231", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: routes to groups of volunteers and its effects compared.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00871", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: During nitroprusside infusion low levels of CPAP do not markedly alter cardiovascular dynamics, but high levels of CPAP (10 cm H2O ), while decreasing QS / QT, produce marked decreases in arterial blood pressure and cardiac output", "completion": "{\"entities\": [{\"text\": \"nitroprusside\", \"type\": \"Chemical\"}, {\"text\": \"H2O\", \"type\": \"Chemical\"}, {\"text\": \"decreases in arterial blood pressure and cardiac output\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01078", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: He developed acute neurologic symptoms of mental confusion, disorientation and irritability, and then lapsed into a deep coma, lasting for approximately 40 hours during the first dose (day 2) of 5-fluorouracil and folinic acid infusion.", "completion": "{\"entities\": [{\"text\": \"confusion\", \"type\": \"Disease\"}, {\"text\": \"disorientation\", \"type\": \"Disease\"}, {\"text\": \"irritability\", \"type\": \"Disease\"}, {\"text\": \"coma\", \"type\": \"Disease\"}, {\"text\": \"5-fluorouracil\", \"type\": \"Chemical\"}, {\"text\": \"folinic acid\", \"type\": \"Chemical\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-02910", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Carbonic anhydrase inhibitors can cause nephrolithiasis.", "completion": "{\"entities\": [{\"text\": \"nephrolithiasis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02436", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This was an exploratory study to investigate lamivudine - resistant hepatitis B virus (HBV) strains in selected lamivudine - na ve HBV carriers with and without human immunodeficiency virus (HIV) co-infection in South African patients.", "completion": "{\"entities\": [{\"text\": \"lamivudine\", \"type\": \"Chemical\"}, {\"text\": \"hepatitis B\", \"type\": \"Disease\"}, {\"text\": \"na\", \"type\": \"Chemical\"}, {\"text\": \"human immunodeficiency virus (HIV) co-infection\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-reassigned-03188", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Nine subjects received 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02571", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 8 g ). During the course of nephrotic syndrome, serum urea concentrations increased significantly faster in sgk1 (-/-) mice than in sgk1 (+/+) mice leading to uremia and a reduced median survival in sgk1 (-/-) mice (29 vs.", "completion": "{\"entities\": [{\"text\": \"nephrotic syndrome\", \"type\": \"Disease\"}, {\"text\": \"urea\", \"type\": \"Chemical\"}, {\"text\": \"uremia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03204", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Among these behavioral effects are decreases in food intake and decreases in amphetamine - induced locomotor activity.", "completion": "{\"entities\": [{\"text\": \"amphetamine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02922", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We report an undiagnosed case of myotonia congenita in a 24 - year - old previously healthy primigravida, who developed life threatening masseter spasm following a standard dose of intravenous suxamethonium", "completion": "{\"entities\": [{\"text\": \"myotonia congenita\", \"type\": \"Disease\"}, {\"text\": \"masseter spasm\", \"type\": \"Disease\"}, {\"text\": \"suxamethonium\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03796", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The patient has been followed for six years and has required pharmacologic doses of pyridoxine", "completion": "{\"entities\": [{\"text\": \"pyridoxine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00073", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We studied a patient with no prior history of neuromuscular disease who became virtually quadriplegic after parenteral magnesium administration for preeclampsia.", "completion": "{\"entities\": [{\"text\": \"neuromuscular disease\", \"type\": \"Disease\"}, {\"text\": \"quadriplegic\", \"type\": \"Disease\"}, {\"text\": \"magnesium\", \"type\": \"Chemical\"}, {\"text\": \"preeclampsia\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03773", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Idraparinux, a Factor Xa inhibitor, is being evaluated in patients with atrial fibrillation.", "completion": "{\"entities\": [{\"text\": \"Idraparinux\", \"type\": \"Chemical\"}, {\"text\": \"atrial fibrillation\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01621", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In behavioral tests, animals treated with terbutaline on PN 2 to 5 showed consistent patterns of hyper - reactivity to novelty and aversive stimuli when assessed in a novel open field, as well as in the acoustic startle response test.", "completion": "{\"entities\": [{\"text\": \"terbutaline\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01445", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Estrogen replacement (17beta-estradiol subcutaneous pellet, 14.", "completion": "{\"entities\": [{\"text\": \"17beta-estradiol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00888", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In other individuals with no underlying atherosclerotic obstruction, coronary occlusion may be due to spasm, thrombus, or both.", "completion": "{\"entities\": [{\"text\": \"atherosclerotic obstruction\", \"type\": \"Disease\"}, {\"text\": \"coronary occlusion\", \"type\": \"Disease\"}, {\"text\": \"spasm\", \"type\": \"Disease\"}, {\"text\": \"thrombus\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00272", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Dothiepin and amitriptyline were equally effective in alleviating the symptoms of depressive illness, and both were significantly superior to placebo.", "completion": "{\"entities\": [{\"text\": \"Dothiepin\", \"type\": \"Chemical\"}, {\"text\": \"amitriptyline\", \"type\": \"Chemical\"}, {\"text\": \"depressive illness\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03181", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Upper lid retraction was frequently noted.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01349", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Potassium was applied by reverse dialysis twice, separated by 75 min.", "completion": "{\"entities\": [{\"text\": \"Potassium\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00918", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Patients were admitted to the hospital for measurement of lithium level, creatinine clearance, urine volume, and maximum osmolality.", "completion": "{\"entities\": [{\"text\": \"lithium\", \"type\": \"Chemical\"}, {\"text\": \"creatinine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00937", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thus, while whole body hyperthermia enhances Adriamycin - mediated antitumor effect, normal tissue toxicity", "completion": "{\"entities\": [{\"text\": \"hyperthermia\", \"type\": \"Disease\"}, {\"text\": \"Adriamycin\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04288", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: o ., and on the eleventh day either scopolamine or placebo, i.", "completion": "{\"entities\": [{\"text\": \"scopolamine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-reassigned-01108", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Val204Asp is disruption of hydrogen", "completion": "{\"entities\": [{\"text\": \"hydrogen\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04007", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 4 mg / kg / day (given intraperitoneally) was administered once a day as these doses have earlier been found to achieve a significant immunosuppressive effect in Sprague - Dawley rats.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00652", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In 28% of patients proteinuria remained unchanged, whereas it increased in 68% of patients.", "completion": "{\"entities\": [{\"text\": \"proteinuria\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02269", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 014 - unit collagenase, heparin enhanced the hematoma volume 3.", "completion": "{\"entities\": [{\"text\": \"heparin\", \"type\": \"Chemical\"}, {\"text\": \"hematoma\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01493", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The incidence of pseudolithiasis", "completion": "{\"entities\": [{\"text\": \"pseudolithiasis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03945", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The anti - dementia effects of s-limonene and s-perillyl alcohol were observed using the passive avoidance test (PA) and the open field habituation test (OFH ). These lemon essential oils showed strong ability to improve memory impaired by scopolamine; however, s-perillyl alcohol relieved the deficit of associative memory in PA only, and did not improve non - associative memory significantly in OFH.", "completion": "{\"entities\": [{\"text\": \"dementia\", \"type\": \"Disease\"}, {\"text\": \"s-limonene\", \"type\": \"Chemical\"}, {\"text\": \"s-perillyl alcohol\", \"type\": \"Chemical\"}, {\"text\": \"memory impaired\", \"type\": \"Disease\"}, {\"text\": \"scopolamine\", \"type\": \"Chemical\"}, {\"text\": \"deficit of associative memory\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-05150", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: The percentage of bruising occurrence was 64% with the injection of 10 seconds duration and 42% in the 30 - second injection.", "completion": "{\"entities\": [{\"text\": \"bruising\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02076", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: of the patients complained of subjective hearing loss", "completion": "{\"entities\": [{\"text\": \"hearing loss\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-reassigned-01864", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 %) reported no benefit.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03837", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It is suggested that the patient had sulfasalazine - induced lupus, which manifested with serositis and pulmonary parenchymal involvement in the absence of joint symptoms.", "completion": "{\"entities\": [{\"text\": \"sulfasalazine\", \"type\": \"Chemical\"}, {\"text\": \"lupus\", \"type\": \"Disease\"}, {\"text\": \"serositis\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00209", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Recurrent reversible acute renal failure from amphotericin.", "completion": "{\"entities\": [{\"text\": \"acute renal failure\", \"type\": \"Disease\"}, {\"text\": \"amphotericin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04846", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Concomitant curcumin administration prevented the cognitive impairment and decreased the increased oxidative stress induced by these antiepileptic drugs.", "completion": "{\"entities\": [{\"text\": \"curcumin\", \"type\": \"Chemical\"}, {\"text\": \"cognitive impairment\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02692", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Simvastatinezetimibe and escitalopram (which she was taking for depression) were discontinued, and other potential causes of hepatotoxicity were excluded.", "completion": "{\"entities\": [{\"text\": \"Simvastatinezetimibe\", \"type\": \"Chemical\"}, {\"text\": \"escitalopram\", \"type\": \"Chemical\"}, {\"text\": \"depression\", \"type\": \"Disease\"}, {\"text\": \"hepatotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03180", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Conjunctival blanching and mydriasis were commonly found.", "completion": "{\"entities\": [{\"text\": \"Conjunctival blanching\", \"type\": \"Disease\"}, {\"text\": \"mydriasis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01631", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: Myocarditis is an increasingly recognized complication associated with the use of clozapine.", "completion": "{\"entities\": [{\"text\": \"Myocarditis\", \"type\": \"Disease\"}, {\"text\": \"clozapine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00642", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: More recently, proteinuria has been reported as a consequence of sirolimus therapy, although the mechanism has remained unclear.", "completion": "{\"entities\": [{\"text\": \"proteinuria\", \"type\": \"Disease\"}, {\"text\": \"sirolimus\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01828", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: v .) or theophylline (3 mg / kg i.", "completion": "{\"entities\": [{\"text\": \"theophylline\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02425", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We also examined the neuroprotective effects of maltolyl p-coumarate in vitro using SH - SY5Y cells.", "completion": "{\"entities\": [{\"text\": \"maltolyl p-coumarate\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03761", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The study investigates if alpha-lipoic acid is neuroprotective against chemotherapy induced neurotoxicity, if mitochondrial damage plays a critical role in toxic neurodegenerative cascade, and if neuroprotective effects of alpha-lipoic acid depend on mitochondria protection.", "completion": "{\"entities\": [{\"text\": \"alpha-lipoic acid\", \"type\": \"Chemical\"}, {\"text\": \"neurotoxicity\", \"type\": \"Disease\"}, {\"text\": \"mitochondrial damage\", \"type\": \"Disease\"}, {\"text\": \"toxic neurodegenerative cascade\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04285", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The present study was carried out to test the effects of L-alpha-glycerylphosphorylcholine (L-alpha-GFC) on memory impairment induced by scopolamine in man.", "completion": "{\"entities\": [{\"text\": \"L-alpha-glycerylphosphorylcholine\", \"type\": \"Chemical\"}, {\"text\": \"L-alpha-GFC\", \"type\": \"Chemical\"}, {\"text\": \"memory impairment\", \"type\": \"Disease\"}, {\"text\": \"scopolamine\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02015", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 17) the addition of sodium bicarbonate (0.", "completion": "{\"entities\": [{\"text\": \"sodium bicarbonate\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00287", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: An autoradiographic study was performed on male F - 344 rats fed diet containing FANFT at a level of 0.", "completion": "{\"entities\": [{\"text\": \"FANFT\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04986", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 7% would choose propofol anaesthesia again.", "completion": "{\"entities\": [{\"text\": \"propofol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01495", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The illicit use of cocaine continues in epidemic proportions and treatment for cocaine overdose remains elusive.", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"cocaine overdose\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00106", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Effects of an inhibitor of angiotensin converting enzyme (Captopril) on pulmonary and renal insufficiency due to intravascular coagulation in the rat.", "completion": "{\"entities\": [{\"text\": \"angiotensin\", \"type\": \"Chemical\"}, {\"text\": \"Captopril\", \"type\": \"Chemical\"}, {\"text\": \"pulmonary and renal insufficiency\", \"type\": \"Disease\"}, {\"text\": \"intravascular coagulation\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01366", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Adult rats given dexamethasone on days 15 and 16 of gestation had more glomeruli with glomerulosclerosis than control rats.", "completion": "{\"entities\": [{\"text\": \"dexamethasone\", \"type\": \"Chemical\"}, {\"text\": \"glomerulosclerosis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04661", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Forty - nine percent of patients were pain free 2 h after rizatriptan, compared with 24.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"rizatriptan\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03916", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Although a dose - response effect has been observed with cisplatin, the dose - limiting toxicities associated with cisplatin (e.", "completion": "{\"entities\": [{\"text\": \"cisplatin\", \"type\": \"Chemical\"}, {\"text\": \"toxicities\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04662", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 3% treated with ergotamine / caffeine (p < or = 0.", "completion": "{\"entities\": [{\"text\": \"ergotamine\", \"type\": \"Chemical\"}, {\"text\": \"caffeine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00003", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The hypotensive effect of 100 mg / kg alpha-methyldopa was also partially reversed by naloxone.", "completion": "{\"entities\": [{\"text\": \"hypotensive\", \"type\": \"Disease\"}, {\"text\": \"alpha-methyldopa\", \"type\": \"Chemical\"}, {\"text\": \"naloxone\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02069", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The effect of different anaesthetic agents in hearing loss following spinal anaesthesia.", "completion": "{\"entities\": [{\"text\": \"hearing loss\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02644", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: ACE inhibition had no significant protective effect.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02456", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These findings demonstrate a sexually - dimorphic interaction between NMDA antagonists and morphine in a persistent pain model that can be distinguished from those observed in acute pain", "completion": "{\"entities\": [{\"text\": \"NMDA\", \"type\": \"Chemical\"}, {\"text\": \"morphine\", \"type\": \"Chemical\"}, {\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"acute pain\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04825", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Clinical experiences in an open and a double - blind trial.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00592", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We present a 43 - year - old man who developed a coronary aneurysm in the right coronary artery 6 months after receiving a paclitaxel - eluting stent.", "completion": "{\"entities\": [{\"text\": \"coronary aneurysm\", \"type\": \"Disease\"}, {\"text\": \"paclitaxel\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-05105", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Dialysis was immediately initiated.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04633", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: On hospital admission, blood pressure of the intubated, bradyarrhythmic patient was 100 / 65 mmHg.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00453", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 6 courses per patient.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00325", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: c .) was injected for various periods into preweanling rats and for 3 weeks into weanling rats.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03970", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Previous anecdotal reports have linked creatine to the development of arrhythmia", "completion": "{\"entities\": [{\"text\": \"creatine\", \"type\": \"Chemical\"}, {\"text\": \"arrhythmia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02599", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Normalizing effects of modafinil on sleep in chronic cocaine users.", "completion": "{\"entities\": [{\"text\": \"modafinil\", \"type\": \"Chemical\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03828", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: One to 2% of patients have elevations of serum transaminases to greater than 3 times the upper limit of normal.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04185", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Nicotine does not appear to enhance thrombosis among humans.", "completion": "{\"entities\": [{\"text\": \"Nicotine\", \"type\": \"Chemical\"}, {\"text\": \"thrombosis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02990", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 025 ). CONCLUSION: The addition of thalidomide to docetaxel in the treatment of prostate cancer significantly increases the frequency of VTE.", "completion": "{\"entities\": [{\"text\": \"thalidomide\", \"type\": \"Chemical\"}, {\"text\": \"docetaxel\", \"type\": \"Chemical\"}, {\"text\": \"prostate cancer\", \"type\": \"Disease\"}, {\"text\": \"VTE\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01017", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This reaction occurred during the sixth and seventh courses of infusional chemotherapy.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00750", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Studies concerning with pathogenesis of gastric hemorrhage and mucosal ulceration produced in atherosclerotic rats are lacking.", "completion": "{\"entities\": [{\"text\": \"gastric hemorrhage\", \"type\": \"Disease\"}, {\"text\": \"atherosclerotic\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03711", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A Phase I study of intravenous (IV) bolus 4'-0-tetrahydropyranyladriamycin (Pirarubicin) was done in 55 patients in good performance status with refractory tumors.", "completion": "{\"entities\": [{\"text\": \"4'-0-tetrahydropyranyladriamycin\", \"type\": \"Chemical\"}, {\"text\": \"Pirarubicin\", \"type\": \"Chemical\"}, {\"text\": \"tumors\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04509", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Apparent diffusion coefficient (ADC) values on the initial MR study were correlated with reversibility of the lesions.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04281", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Serial epilepsy caused by levodopa/carbidopa administration in two patients on hemodialysis.", "completion": "{\"entities\": [{\"text\": \"epilepsy\", \"type\": \"Disease\"}, {\"text\": \"levodopa/carbidopa\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03986", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Decrease of fetal length was the only signs of the DFU developmental toxicity observed in pups exposed to the highest compound dose.", "completion": "{\"entities\": [{\"text\": \"DFU\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01684", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05) elevation of heart weight, serum marker enzymes, lipid peroxidation and Ca + 2 ATPase level whereas there was a significant (P < 0.", "completion": "{\"entities\": [{\"text\": \"Ca\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03059", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5-azacytidine potentiates initiation induced by carcinogens in rat liver.", "completion": "{\"entities\": [{\"text\": \"5-azacytidine\", \"type\": \"Chemical\"}, {\"text\": \"initiation induced by carcinogens\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04375", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Testosterone contributes to the development of hypertension and renal injury in male DS rats on HS diet possibly through upregulation of the intrarenal renin - angiotensin", "completion": "{\"entities\": [{\"text\": \"Testosterone\", \"type\": \"Chemical\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}, {\"text\": \"renal injury\", \"type\": \"Disease\"}, {\"text\": \"angiotensin\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00312", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A case of triamterene nephrolithiasis is reported in a man after 4 years of hydrochlorothiazide-triamterene therapy for hypertension.", "completion": "{\"entities\": [{\"text\": \"triamterene\", \"type\": \"Chemical\"}, {\"text\": \"nephrolithiasis\", \"type\": \"Disease\"}, {\"text\": \"hydrochlorothiazide-triamterene\", \"type\": \"Chemical\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04675", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 3% with ergotamine / caffeine.", "completion": "{\"entities\": [{\"text\": \"ergotamine\", \"type\": \"Chemical\"}, {\"text\": \"caffeine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04515", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 %) showed higher than normal ADC values on initial MR images, and all showed complete resolution on follow - up images.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03020", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Intracranial aneurysms and cocaine abuse: analysis of prognostic indicators.", "completion": "{\"entities\": [{\"text\": \"Intracranial aneurysms\", \"type\": \"Disease\"}, {\"text\": \"cocaine abuse\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01404", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: At six months post - CAB, patients with severe anemia had a Hb mean value of 10.", "completion": "{\"entities\": [{\"text\": \"anemia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02498", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This response was restricted to the striatum and contrasted sharply with unresponsive eGFP - microglia in surrounding brain areas that are not damaged by METH.", "completion": "{\"entities\": [{\"text\": \"METH\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05143", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: DESIGN: This study was designed as within - subject, quasi - experimental research.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02397", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 mg / dL occurred in 4.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04461", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pre - and posttransplant crossmatching was done when possible.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03191", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Report on arrhythmia and other findings.", "completion": "{\"entities\": [{\"text\": \"arrhythmia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02163", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 mg / kg) on cardiac rate and ultrasound production were examined in 2 -, 8 -, 15 -, and 20 - day - old rats.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00243", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The timolol - treated patients showed a small but significant increase in heart size from baseline in contrast to a decrease in the placebo group.", "completion": "{\"entities\": [{\"text\": \"timolol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01824", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Many of these patients are taking pentoxifylline (Trental ), a methylxanthine derivative which may improve intermittent claudication.", "completion": "{\"entities\": [{\"text\": \"pentoxifylline\", \"type\": \"Chemical\"}, {\"text\": \"Trental\", \"type\": \"Chemical\"}, {\"text\": \"methylxanthine\", \"type\": \"Chemical\"}, {\"text\": \"intermittent claudication\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02289", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 3 days, and given clozapine, gradually increased to an average daily dose of 282 +/- 203 mg (3.", "completion": "{\"entities\": [{\"text\": \"clozapine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01104", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A total of 177 patients were diagnosed as allergic to beta-lactam antibiotics.", "completion": "{\"entities\": [{\"text\": \"allergic\", \"type\": \"Disease\"}, {\"text\": \"beta-lactam\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04117", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 2 %) required discontinuation of spironolactone due to hyperkalemia (n = 33) or renal failure (n = 34 ). Patients who developed hyperkalemia were older and more likely to have diabetes, had higher baseline serum potassium levels and lower baseline potassium supplement doses, and were more likely to be treated with beta - blockers than controls (n = 134 ). Patients who developed renal insufficiency had lower baseline body weight and higher baseline serum creatinine, required higher doses of loop diuretics, and were more likely to be treated with thiazide diuretics than controls.", "completion": "{\"entities\": [{\"text\": \"spironolactone\", \"type\": \"Chemical\"}, {\"text\": \"hyperkalemia\", \"type\": \"Disease\"}, {\"text\": \"renal failure\", \"type\": \"Disease\"}, {\"text\": \"diabetes\", \"type\": \"Disease\"}, {\"text\": \"potassium\", \"type\": \"Chemical\"}, {\"text\": \"renal insufficiency\", \"type\": \"Disease\"}, {\"text\": \"creatinine\", \"type\": \"Chemical\"}, {\"text\": \"thiazide\", \"type\": \"Chemical\"}]}", "n_entities": 8}
{"ref": "bc5cdr-train-00568", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The relative amounts of alphaENaC, betaENaC and gammaENaC mRNAs were determined in kidneys from these rats by real - time quantitative TaqMan PCR, and the amounts of proteins by Western blot.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01112", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: PG was well tolerated by all 54 patients.", "completion": "{\"entities\": [{\"text\": \"PG\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00317", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Adriamycin inhibited cell growth and the rhythmic contractions characteristic of myocardial cells in culture.", "completion": "{\"entities\": [{\"text\": \"Adriamycin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02724", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The effect of the converting enzyme inhibitor (CEI) enalapril was assessed in Munich - Wistar rats with established adriamycin nephrosis.", "completion": "{\"entities\": [{\"text\": \"enalapril\", \"type\": \"Chemical\"}, {\"text\": \"adriamycin\", \"type\": \"Chemical\"}, {\"text\": \"nephrosis\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04538", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Microscopic observation showed the configuration of exencephaly at E13.", "completion": "{\"entities\": [{\"text\": \"exencephaly\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04058", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In recent years, evidence from animal models of Parkinson's disease has provided important information to understand the effect of specific receptor and post - receptor molecular mechanisms underlying the development of dyskinetic movements.", "completion": "{\"entities\": [{\"text\": \"Parkinson's disease\", \"type\": \"Disease\"}, {\"text\": \"dyskinetic movements\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03886", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: (R)-alpha-methylhistamine (RAMH )(5 microg i.", "completion": "{\"entities\": [{\"text\": \"(R)-alpha-methylhistamine\", \"type\": \"Chemical\"}, {\"text\": \"RAMH\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04273", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the liver both the content of RNA and the biosynthesis of ribosomal RNA increased while both the RNA content and ribosomal RNA biosynthesis were reduced in the gastrocnemius muscle.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04720", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: There were 13 cases of adverse reactions (0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04131", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Multivariate stepwise logistic regression analysis using preoperative and postoperative variables identified that an increase of serum creatinine compared with average at 1 year, 3 months, and 4 weeks postoperatively were independent risk factors for the development of CRF or ESRD with odds ratios of 2.", "completion": "{\"entities\": [{\"text\": \"creatinine\", \"type\": \"Chemical\"}, {\"text\": \"CRF\", \"type\": \"Disease\"}, {\"text\": \"ESRD\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03375", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Dis ., 17 (2004 ), 219] but information regarding the proteome is still lacking.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01981", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The optimal time for the initial dose of carbon tetrachloride was after 14 days on phenobarbitone", "completion": "{\"entities\": [{\"text\": \"carbon tetrachloride\", \"type\": \"Chemical\"}, {\"text\": \"phenobarbitone\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04547", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Seizure end points included latency to forelimb or hindlimb clonus, latency to clonic running seizure and latency to jumping bouncing seizure.", "completion": "{\"entities\": [{\"text\": \"Seizure\", \"type\": \"Disease\"}, {\"text\": \"seizure\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03346", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In these 62 patients, no other causes for renal failure could be identified.", "completion": "{\"entities\": [{\"text\": \"renal failure\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01352", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In microdialysis experiments, the lines did not differ in basal release of ACh, and 50 mM KCl increased ACh output in both lines of mice.", "completion": "{\"entities\": [{\"text\": \"ACh\", \"type\": \"Chemical\"}, {\"text\": \"KCl\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00254", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Signs of vitamin D3 toxicity were not observed in nonlactating nonpregnant cows; however, pregnant cows commonly developed severe signs of vitamin D3 toxicity and 10 of 17 cows died.", "completion": "{\"entities\": [{\"text\": \"vitamin D3\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01469", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 1 ), and the number needed to treat to cause 1 event was 170 (95% CI 100 - 582) over 3.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04405", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: They also provide evidence for estradiol", "completion": "{\"entities\": [{\"text\": \"estradiol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04813", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Hyperbaric oxygen therapy for control of intractable cyclophosphamide - induced hemorrhagic cystitis.", "completion": "{\"entities\": [{\"text\": \"oxygen\", \"type\": \"Chemical\"}, {\"text\": \"cyclophosphamide\", \"type\": \"Chemical\"}, {\"text\": \"hemorrhagic cystitis\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04874", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The incidence of adverse events in the 2 groups was similar during the first 2 weeks of product use (evaluation population: 55.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02372", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: Warfarin - induced cerebral haemorrhages are a major clinical problem with a high fatality rate.", "completion": "{\"entities\": [{\"text\": \"Warfarin\", \"type\": \"Chemical\"}, {\"text\": \"cerebral haemorrhages\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02391", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The primary outcome was a postdose SCr increase > or = 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01519", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We postulate that by virtue of its direct blocking action on IKr, ketoconazole alone may prolong QT interval and induce TdP.", "completion": "{\"entities\": [{\"text\": \"ketoconazole\", \"type\": \"Chemical\"}, {\"text\": \"TdP\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02396", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: SCr increases > or = 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00522", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 8 ). The adjusted odds ratio was 2.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02596", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: For almost all cognitive measures, there were no medication by age - interaction effects, which indicates that the 2 age groups exhibited similar responses to the medication challenge.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-05122", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Of our control group (n = 50 ), 21 patients (42 %) were established hepatitis.", "completion": "{\"entities\": [{\"text\": \"hepatitis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01984", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Amiloride reduced the drinking and urine volume of rats in an acute (6 or 12 h) and a subacute (3 days) experiment.", "completion": "{\"entities\": [{\"text\": \"Amiloride\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04036", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The average duration of treatment before the onset of jaundice was 61 days.", "completion": "{\"entities\": [{\"text\": \"jaundice\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01880", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Survival for patients with advanced head and neck carcinoma and esophageal carcinoma is poor with radiotherapy and / or surgery.", "completion": "{\"entities\": [{\"text\": \"head and neck carcinoma\", \"type\": \"Disease\"}, {\"text\": \"esophageal carcinoma\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03172", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: The combination of paclitaxel, cisplatin, and gemcitabine is well tolerated and shows high activity in metastatic NSCLC.", "completion": "{\"entities\": [{\"text\": \"paclitaxel\", \"type\": \"Chemical\"}, {\"text\": \"cisplatin\", \"type\": \"Chemical\"}, {\"text\": \"gemcitabine\", \"type\": \"Chemical\"}, {\"text\": \"NSCLC\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03860", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 013 ). Antiemetic requirements were reduced from 24% and 31% to 7 %(P = 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02111", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cocaine - induced mood disorder: prevalence rates and psychiatric symptoms in an outpatient cocaine - dependent sample.", "completion": "{\"entities\": [{\"text\": \"Cocaine\", \"type\": \"Chemical\"}, {\"text\": \"mood disorder\", \"type\": \"Disease\"}, {\"text\": \"psychiatric\", \"type\": \"Disease\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02206", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: injections of organ specific three drugs (AAP: 500 mg / Kg for 24 h; AMI: 50 mg / Kg / day for four days; DOX: 20 mg / Kg for 48 h ). Parameters of study included analysis of serum chemistry (ALT, BUN and CPK ), and orderly fragmentation of genomic DNA (both endonuclease - dependent and independent) in addition to microscopic evaluation of damage and / or protection in corresponding PAS stained tissues.", "completion": "{\"entities\": [{\"text\": \"AAP\", \"type\": \"Chemical\"}, {\"text\": \"AMI\", \"type\": \"Chemical\"}, {\"text\": \"DOX\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01283", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Conformationally restricted analogs of BD1008 and an antisense oligodeoxynucleotide targeting sigma1 receptors produce anti - cocaine effects in mice.", "completion": "{\"entities\": [{\"text\": \"BD1008\", \"type\": \"Chemical\"}, {\"text\": \"oligodeoxynucleotide\", \"type\": \"Chemical\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03461", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 2 %) than the patients who received prazosin (12.", "completion": "{\"entities\": [{\"text\": \"prazosin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04607", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The most important findings were that compared with values in control subjects, end - systolic left ventricular posterior wall dimension and percent of left ventricular posterior wall thickening in doxorubicin - treated patients were decreased at baseline study and these findings were more clearly delineated with dobutamine stimulation.", "completion": "{\"entities\": [{\"text\": \"doxorubicin\", \"type\": \"Chemical\"}, {\"text\": \"dobutamine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03486", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The nephrotoxic potential of amphotericin B (5 mg / kg per day intraperitoneally for 3 weeks) has been investigated in salt - depleted, normal - salt, and salt - loaded rats.", "completion": "{\"entities\": [{\"text\": \"nephrotoxic\", \"type\": \"Disease\"}, {\"text\": \"amphotericin B\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02591", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: Sirolimus induces or aggravates pre - existing proteinuria in an unpredictable subset of renal allograft recipients.", "completion": "{\"entities\": [{\"text\": \"Sirolimus\", \"type\": \"Chemical\"}, {\"text\": \"proteinuria\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03168", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 4% of patients, respectively.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02875", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Similarly, in patient diaries, although both treatments caused reduction in subjective dyskinesia scores during the days of intervention, the effect was sustained for 3 days after the intervention for the real rTMS only.", "completion": "{\"entities\": [{\"text\": \"dyskinesia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01890", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Verapamil - induced carbamazepine neurotoxicity.", "completion": "{\"entities\": [{\"text\": \"Verapamil\", \"type\": \"Chemical\"}, {\"text\": \"carbamazepine\", \"type\": \"Chemical\"}, {\"text\": \"neurotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01584", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: All had myofibre necrosis but only 3 had an inflammatory infiltrate.", "completion": "{\"entities\": [{\"text\": \"necrosis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04121", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Their use in orthotopic liver transplantation (OLTX) has dramatically improved success rates.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00470", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Concurrent treatment of both dietary groups with Warfarin produced massive focal calcification of the artery media in the ad libitum - fed rats but no detectable artery calcification in the restricted - diet, growth - inhibited group.", "completion": "{\"entities\": [{\"text\": \"Warfarin\", \"type\": \"Chemical\"}, {\"text\": \"calcification of the artery\", \"type\": \"Disease\"}, {\"text\": \"artery calcification\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04349", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The catheters were changed, and hemodynamics stabilized at lower catecholamine", "completion": "{\"entities\": [{\"text\": \"catecholamine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02265", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 350 - unit collagenase, the amount of bleeding was measured using a hemoglobin assay developed in the present study and was compared with the morphologically determined hematoma volume.", "completion": "{\"entities\": [{\"text\": \"bleeding\", \"type\": \"Disease\"}, {\"text\": \"hematoma\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01854", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Angina and ischemic electrocardiographic changes occurred after administration of oral dipyridamole in four patients awaiting urgent myocardial revascularization procedures.", "completion": "{\"entities\": [{\"text\": \"Angina\", \"type\": \"Disease\"}, {\"text\": \"dipyridamole\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04272", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Liver enlargement and muscle wastage occurred in Wistar rats following the subcutaneous administration of prednisolone.", "completion": "{\"entities\": [{\"text\": \"Liver enlargement\", \"type\": \"Disease\"}, {\"text\": \"muscle wastage\", \"type\": \"Disease\"}, {\"text\": \"prednisolone\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03618", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Changes in aortic morphology were examined by light - and transmission - electron microscopy (TEM ). In addition, the endothelial permeability and the penetration through the aortic wall of albumin were studied 10 minutes, 24 and 48 hours after i.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03081", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The mean steady - state plasma and CSF methotrexate concentrations achieved were 1.", "completion": "{\"entities\": [{\"text\": \"methotrexate\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03322", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After 12 weeks, rats were sacrificed and their kidneys harvested.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00171", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A 47 - year - old patient suffering from coronary artery disease was admitted to the CCU in shock with III.", "completion": "{\"entities\": [{\"text\": \"coronary artery disease\", \"type\": \"Disease\"}, {\"text\": \"shock\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03604", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: INTERPRETATION: Tranexamic acid retains its convulsive action within FS.", "completion": "{\"entities\": [{\"text\": \"Tranexamic acid\", \"type\": \"Chemical\"}, {\"text\": \"convulsive\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02953", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The site of common side effects of sumatriptan.", "completion": "{\"entities\": [{\"text\": \"sumatriptan\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00250", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 x 10 (6) IU vitamin D3) were associated with prolonged hypercalcemia, hyperphosphatemia, and large increases of vitamin D3 and its metabolites in the blood plasma of nonlactating nonpregnant and pregnant Jersey cows.", "completion": "{\"entities\": [{\"text\": \"vitamin D3\", \"type\": \"Chemical\"}, {\"text\": \"hypercalcemia\", \"type\": \"Disease\"}, {\"text\": \"hyperphosphatemia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01527", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: o .) showed significant improvement in memory scores of young and aged mice.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02609", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: For comparison of sleep architecture variables, 12 healthy comparison participants underwent a single night of experimental polysomnography that followed 1 night of accommodation polysomnography.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01111", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Challenge tests with AX were performed in 23 subjects (43 %) to establish the diagnosis of immediate allergic reaction to AX, and in 15 cases (28 %) both skin test and RAST for AX were negative.", "completion": "{\"entities\": [{\"text\": \"AX\", \"type\": \"Chemical\"}, {\"text\": \"allergic reaction\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01200", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The serum level of potassium was observed to be 8.", "completion": "{\"entities\": [{\"text\": \"potassium\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04109", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: A previous randomized controlled trial evaluating the use of spironolactone in heart failure patients reported a low risk of hyperkalemia (2 %) and renal insufficiency (0 %). Because treatments for heart failure have changed since the benefits of spironolactone were reported, the prevalence of these complications may differ in current clinical practice.", "completion": "{\"entities\": [{\"text\": \"spironolactone\", \"type\": \"Chemical\"}, {\"text\": \"heart failure\", \"type\": \"Disease\"}, {\"text\": \"hyperkalemia\", \"type\": \"Disease\"}, {\"text\": \"renal insufficiency\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02367", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Among 593 patients with cerebral haemorrhage, 59 (10 %) were assessed as related to warfarin treatment.", "completion": "{\"entities\": [{\"text\": \"cerebral haemorrhage\", \"type\": \"Disease\"}, {\"text\": \"warfarin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01545", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After verifying the epidural space, bupivacaine and triamcinolone diacetate were injected.", "completion": "{\"entities\": [{\"text\": \"bupivacaine\", \"type\": \"Chemical\"}, {\"text\": \"triamcinolone diacetate\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00789", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Deficits in learning and memory: parahippocampal hyperactivity and frontocortical hypoactivity in cannabis users.", "completion": "{\"entities\": [{\"text\": \"Deficits in learning and memory\", \"type\": \"Disease\"}, {\"text\": \"hyperactivity\", \"type\": \"Disease\"}, {\"text\": \"cannabis\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01864", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In order to elucidate the role of the catecholaminergic system in the cataleptogenic effect of delta 9-tetrahydrocannabinol (THC ), the effect of pretreatment with 6-hydroxydopamine (6-OHDA) or with desipramine and 6-OHDA and lesions of the locus coeruleus were investigated in rats.", "completion": "{\"entities\": [{\"text\": \"delta 9-tetrahydrocannabinol\", \"type\": \"Chemical\"}, {\"text\": \"THC\", \"type\": \"Chemical\"}, {\"text\": \"6-hydroxydopamine\", \"type\": \"Chemical\"}, {\"text\": \"6-OHDA\", \"type\": \"Chemical\"}, {\"text\": \"desipramine\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-02615", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: Morning - dosed modafinil promotes nocturnal sleep, normalizes sleep architecture, and decreases daytime sleepiness in abstinent cocaine users.", "completion": "{\"entities\": [{\"text\": \"modafinil\", \"type\": \"Chemical\"}, {\"text\": \"daytime sleepiness\", \"type\": \"Disease\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00542", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 1 - 10 microg / side) did not change basal locomotor activity.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01775", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Fifty - eight patients (78 %) had normal renal tests, whereas 16 patients (22 %) had renal abnormalities.", "completion": "{\"entities\": [{\"text\": \"renal abnormalities\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04240", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Recurrence was studied in 82 evaluable patients after 1 year of follow - up and in 72 patients followed for 2 - 3 years (mean 32 months ). Of the 82 patients studied after 1 year, 23 had primary and 59 recurrent disease.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04562", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Recognition of variant ventricular tachycardia is important because therapy differs from that of classic ventricular tachycardia", "completion": "{\"entities\": [{\"text\": \"ventricular tachycardia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-reassigned-00116", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05 ). Pretreatment with S.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02130", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Either alpha-T or alpha-TAc increases membrane packing and prevents TAM partition into model membranes.", "completion": "{\"entities\": [{\"text\": \"alpha-T\", \"type\": \"Chemical\"}, {\"text\": \"alpha-TAc\", \"type\": \"Chemical\"}, {\"text\": \"TAM\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01892", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Two patients with signs of carbamazepine neurotoxicity after combined treatment with verapamil showed complete recovery after discontinuation of the calcium entry blocker.", "completion": "{\"entities\": [{\"text\": \"carbamazepine\", \"type\": \"Chemical\"}, {\"text\": \"neurotoxicity\", \"type\": \"Disease\"}, {\"text\": \"verapamil\", \"type\": \"Chemical\"}, {\"text\": \"calcium\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00905", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 4 hours with theophylline.", "completion": "{\"entities\": [{\"text\": \"theophylline\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04481", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The risk of bladder cancer doubled for every 10 g increment in cyclophosphamide (OR = 2.", "completion": "{\"entities\": [{\"text\": \"bladder cancer\", \"type\": \"Disease\"}, {\"text\": \"cyclophosphamide\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00074", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The serum magnesium concentration was 3.", "completion": "{\"entities\": [{\"text\": \"magnesium\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03510", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Both obstructive (P less than 0.05) and central apnoea (P less than 0.", "completion": "{\"entities\": [{\"text\": \"obstructive (P less than 0.05) and central apnoea\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03705", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Alopecia, paresthesias, and arthralgias / myalgias have occurred frequently, but with one exception (a grade 3 myalgia) they have been grade 1 or 2.", "completion": "{\"entities\": [{\"text\": \"Alopecia\", \"type\": \"Disease\"}, {\"text\": \"paresthesias\", \"type\": \"Disease\"}, {\"text\": \"arthralgias\", \"type\": \"Disease\"}, {\"text\": \"myalgia\", \"type\": \"Disease\"}, {\"text\": \"myalgias\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-04119", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: End-stage renal disease (ESRD) after orthotopic liver transplantation (OLTX) using calcineurin - based immunotherapy: risk of development and treatment.", "completion": "{\"entities\": [{\"text\": \"End-stage renal disease\", \"type\": \"Disease\"}, {\"text\": \"ESRD\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02718", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Lipopolysaccharide pretreatment did not affect the basal body temperature or methamphetamine - elicited hyperthermia three days later.", "completion": "{\"entities\": [{\"text\": \"Lipopolysaccharide\", \"type\": \"Chemical\"}, {\"text\": \"methamphetamine\", \"type\": \"Chemical\"}, {\"text\": \"hyperthermia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02838", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Explicit episodic memory for sensory - discriminative components of capsaicin - induced pain: immediate and delayed ratings.", "completion": "{\"entities\": [{\"text\": \"capsaicin\", \"type\": \"Chemical\"}, {\"text\": \"pain\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01752", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: per liter failed to increase calcium influx into the myocardial cell.", "completion": "{\"entities\": [{\"text\": \"calcium\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05221", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In rats, detection of apomorphine - induced hyperactivity was facilitated by a period of acclimatization to the test conditions.", "completion": "{\"entities\": [{\"text\": \"apomorphine\", \"type\": \"Chemical\"}, {\"text\": \"hyperactivity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03906", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Such an effect was, however, reversed in presence of RAMH.", "completion": "{\"entities\": [{\"text\": \"RAMH\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03084", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: All 20 patients responded to this regimen, 16 / 20 (80 %) achieved a complete remission, and 20% obtained a partial remission.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03479", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 135 mM of normal [Ca] o was effective to reduce BF by 40 +/- 13 %. All negative chronotropic effects were BF - dependent.", "completion": "{\"entities\": [{\"text\": \"Ca\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01412", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Reversible dilated cardiomyopathy related to amphotericin B therapy.", "completion": "{\"entities\": [{\"text\": \"dilated cardiomyopathy\", \"type\": \"Disease\"}, {\"text\": \"amphotericin B\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-00061", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: p .) injected with 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03026", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: The patients in the study group were significantly younger than the patients in the control group (P < 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03599", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The degree of these seizures increased with increasing concentration of tAMCA.", "completion": "{\"entities\": [{\"text\": \"seizures\", \"type\": \"Disease\"}, {\"text\": \"tAMCA\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00821", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Gastrointestinal bleed, seizures, infection, and acute renal failure were documented in seven (10 %), five (7.", "completion": "{\"entities\": [{\"text\": \"Gastrointestinal bleed\", \"type\": \"Disease\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}, {\"text\": \"infection\", \"type\": \"Disease\"}, {\"text\": \"acute renal failure\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01855", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: To our knowledge, this has not previously been reported as a side effect of preoperative dipyridamole therapy, although dipyridamole - induced myocardial ischemia has been demonstrated to occur in animals and humans with coronary artery disease.", "completion": "{\"entities\": [{\"text\": \"dipyridamole\", \"type\": \"Chemical\"}, {\"text\": \"myocardial ischemia\", \"type\": \"Disease\"}, {\"text\": \"coronary artery disease\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00147", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 213, Methotrexate, Cyclophosphamide, Actomycin-D, and Cisplatin.", "completion": "{\"entities\": [{\"text\": \"Methotrexate\", \"type\": \"Chemical\"}, {\"text\": \"Cyclophosphamide\", \"type\": \"Chemical\"}, {\"text\": \"Actomycin-D\", \"type\": \"Chemical\"}, {\"text\": \"Cisplatin\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04493", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thirty milliliters of blood was obtained for isolation of peripheral blood mononuclear cells after each treatment period.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00344", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Clomipramine - induced sleep disturbance does not impair its prolactin - releasing action.", "completion": "{\"entities\": [{\"text\": \"Clomipramine\", \"type\": \"Chemical\"}, {\"text\": \"sleep disturbance\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05213", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Facilitation of memory retrieval by pre - test morphine and its state dependency in the step - through type passive avoidance learning test in mice.", "completion": "{\"entities\": [{\"text\": \"morphine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02510", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Course following treatment modifications.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02756", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: a total of 13 patients were referred to the Danish Cholinesterase Research Unit after ECT during 38 months.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00847", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Capecitabine has a well - established safety profile and can be given safely to patients with advanced age, hepatic and renal dysfunctions", "completion": "{\"entities\": [{\"text\": \"Capecitabine\", \"type\": \"Chemical\"}, {\"text\": \"hepatic and renal dysfunctions\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00757", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Gastric acid back - diffusion, mucosal LPO generation, histamine concentration, microvascular permeability, luminal hemoglobin content and ulcer areas were determined.", "completion": "{\"entities\": [{\"text\": \"histamine\", \"type\": \"Chemical\"}, {\"text\": \"luminal\", \"type\": \"Chemical\"}, {\"text\": \"ulcer\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03829", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These episodes are asymptomatic and reversible when therapy is discontinued.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04778", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Seven patients developed glucose tolerance curves characteristic of diabetes but these were mild, did not require treatment and returned to normal on ceasing didanosine", "completion": "{\"entities\": [{\"text\": \"glucose tolerance curves\", \"type\": \"Disease\"}, {\"text\": \"diabetes\", \"type\": \"Disease\"}, {\"text\": \"didanosine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02635", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Using puromycin aminonucleoside nephrosis (PAN) rats, we studied early ultrastructural and permeability changes in relation to the expression of the podocyte - associated molecules nephrin, a - actinin, dendrin, and plekhh2, the last two of which were only recently discovered in podocytes.", "completion": "{\"entities\": [{\"text\": \"puromycin aminonucleoside\", \"type\": \"Chemical\"}, {\"text\": \"nephrosis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05175", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It could be inferred that gum Arabic treatment has induced a modest amelioration of some of the histological and biochemical indices of GM nephrotoxicity.", "completion": "{\"entities\": [{\"text\": \"gum Arabic\", \"type\": \"Chemical\"}, {\"text\": \"GM\", \"type\": \"Chemical\"}, {\"text\": \"nephrotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01098", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Immediate allergic reactions to amoxicillin.", "completion": "{\"entities\": [{\"text\": \"allergic reactions\", \"type\": \"Disease\"}, {\"text\": \"amoxicillin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01662", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: Clonidine, used alone or with methylphenidate, appears safe and well tolerated in childhood ADHD.", "completion": "{\"entities\": [{\"text\": \"Clonidine\", \"type\": \"Chemical\"}, {\"text\": \"methylphenidate\", \"type\": \"Chemical\"}, {\"text\": \"ADHD\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03145", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: VNB was well tolerated and zero instances of WHO grade 4 nonhematologic toxicity occurred.", "completion": "{\"entities\": [{\"text\": \"VNB\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04899", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Monkeys with acute (short - term) MPTP exposure, rapid symptom onset and short symptom duration prior to initiation of levodopa therapy developed dyskinesia between 11 and 24 days of daily levodopa administration.", "completion": "{\"entities\": [{\"text\": \"MPTP\", \"type\": \"Chemical\"}, {\"text\": \"levodopa\", \"type\": \"Chemical\"}, {\"text\": \"dyskinesia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-reassigned-00245", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: A total of 155 (75.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03798", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: NRA0160, 5 - [2- (4- (3 - fluorobenzylidene) piperidin-1-yl) ethyl] - 4 -(4-fluorophenyl) thiazole-2-carboxamide, has a high affinity for human cloned dopamine D4.", "completion": "{\"entities\": [{\"text\": \"NRA0160\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}, {\"text\": \"5 - [2- ( 4- ( 3 - fluorobenzylidene) piperidin-1-yl) ethyl] - 4 -(4-fluorophenyl) thiazole-2-carboxamide\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00561", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Patients receiving the drug should be monitored with liver function tests along with complete blood cell counts.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00666", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 7 (3 to 12) g / d after conversion (P =. 01 ). Mean serum creatinine level before conversion was 2.", "completion": "{\"entities\": [{\"text\": \"creatinine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02772", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Any pain during the reduction was rated by the orthopaedic surgeon treating the patient according to the Children' s Hospital of Eastern Ontario Pain Scale (CHEOPS ). RESULTS: The average time from intravenous administration of ketamine to manipulation of the fracture or dislocation was one minute and thirty - six seconds (range, twenty seconds to five minutes ), and the average time from intramuscular administration to manipulation was four minutes and forty - two seconds (range, sixty seconds to fifteen minutes ). The average score according to the Children' s Hospital of Eastern Ontario Pain Scale was 6.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"Pain\", \"type\": \"Disease\"}, {\"text\": \"ketamine\", \"type\": \"Chemical\"}, {\"text\": \"fracture\", \"type\": \"Disease\"}, {\"text\": \"dislocation\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-04465", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The fifth case had features of thrombotic microangiopathy related to an antiphospholipid syndrome in a patient with systemic lupus erythematosus.", "completion": "{\"entities\": [{\"text\": \"thrombotic microangiopathy\", \"type\": \"Disease\"}, {\"text\": \"antiphospholipid syndrome\", \"type\": \"Disease\"}, {\"text\": \"systemic lupus erythematosus\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-reassigned-00772", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Amiodarone - induced myxoedema coma.", "completion": "{\"entities\": [{\"text\": \"Amiodarone\", \"type\": \"Chemical\"}, {\"text\": \"myxoedema coma\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04452", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: DNA analysis revealed low amounts of a 4.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00768", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We then examined the morphology, expression of beclin 1 gene, mitochondrial permeability transition (MPT ), and Na +- K + ATPase activity in vivo.", "completion": "{\"entities\": [{\"text\": \"K\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01204", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: An unusual toxic reaction to axillary block by mepivacaine with adrenaline.", "completion": "{\"entities\": [{\"text\": \"mepivacaine\", \"type\": \"Chemical\"}, {\"text\": \"adrenaline\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-00178", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 005) than patients without dyskinesia.", "completion": "{\"entities\": [{\"text\": \"dyskinesia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00291", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the forestomach, and also in the liver, aspirin did not affect the FANFT - induced increase in labeling index.", "completion": "{\"entities\": [{\"text\": \"aspirin\", \"type\": \"Chemical\"}, {\"text\": \"FANFT\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02574", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pneumocystis pneumonia (PCP ), a common opportunistic infection in HIV-infected individuals, is generally treated with high doses of co-trimoxazole.", "completion": "{\"entities\": [{\"text\": \"Pneumocystis pneumonia\", \"type\": \"Disease\"}, {\"text\": \"PCP\", \"type\": \"Disease\"}, {\"text\": \"opportunistic infection\", \"type\": \"Disease\"}, {\"text\": \"HIV-infected\", \"type\": \"Disease\"}, {\"text\": \"co-trimoxazole\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-02503", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Neurotoxicity is a potentially serious toxic effect.", "completion": "{\"entities\": [{\"text\": \"Neurotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04423", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: PURPOSE: The multidrug resistance protein 2 (MRP2) is a drug efflux transporter that is expressed predominantly at the apical domain of hepatocytes but seems also to be expressed at the apical membrane of brain capillary endothelial cells that form the blood - brain barrier (BBB ). MRP2 is absent in the transport - deficient (TR (-)) Wistar rat mutant, so that this rat strain was very helpful in defining substrates of MRP2 by comparing tissue concentrations or functional activities of compounds in MRP2 - deficient rats with those in transport - competent Wistar rats.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04550", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: EEG recordings were made in SJL, A / J and C57BL / 6J mice revealing a close correspondence between electrical activity and behavior.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01089", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Erythema multiforme and hypersensitivity myocarditis caused by ampicillin.", "completion": "{\"entities\": [{\"text\": \"Erythema multiforme\", \"type\": \"Disease\"}, {\"text\": \"hypersensitivity myocarditis\", \"type\": \"Disease\"}, {\"text\": \"ampicillin\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00619", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The dose of gabapentin was 1, 800 mg per os, in a single administration.", "completion": "{\"entities\": [{\"text\": \"gabapentin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-reassigned-01181", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Associations of Ozone and PM2.", "completion": "{\"entities\": [{\"text\": \"Ozone\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02065", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The serum of six affected workers and five controls was tested for autoantibodies that react with human liver cytochrome - P450 2E1 (P450 2E1) and P58 protein disulphide isomerase isoform (P58 ). FINDINGS: The liver biopsy sample showed hepatocellular necrosis which was prominent in perivenular zone three and extended focally from portal tracts to portal tracts and centrilobular areas (bridging necrosis ). Trifluoroacetyl - adducted proteins were detected in surviving hepatocytes.", "completion": "{\"entities\": [{\"text\": \"necrosis\", \"type\": \"Disease\"}, {\"text\": \"Trifluoroacetyl\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04086", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Therefore, like VPA, the finding that VPU could drastically reduce pilocarpine - induced increases in glutamate and aspartate should account, at least partly, for its anticonvulsant activity observed in pilocarpine - induced seizure", "completion": "{\"entities\": [{\"text\": \"VPA\", \"type\": \"Chemical\"}, {\"text\": \"VPU\", \"type\": \"Chemical\"}, {\"text\": \"pilocarpine\", \"type\": \"Chemical\"}, {\"text\": \"glutamate\", \"type\": \"Chemical\"}, {\"text\": \"aspartate\", \"type\": \"Chemical\"}, {\"text\": \"seizure\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-02109", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Choreatiform hyperkinesias are known to be occasional movement abnormalities during intoxications with cocaine but not opiates.", "completion": "{\"entities\": [{\"text\": \"Choreatiform hyperkinesias\", \"type\": \"Disease\"}, {\"text\": \"movement abnormalities\", \"type\": \"Disease\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01212", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: We clinically and pathologically analyzed renal allografts from 1 9 renal transplant patients treated with tacrolimus (FK506) for more than 1 year.", "completion": "{\"entities\": [{\"text\": \"tacrolimus\", \"type\": \"Chemical\"}, {\"text\": \"FK506\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01650", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Clonidine for attention-deficit/hyperactivity disorder: II.", "completion": "{\"entities\": [{\"text\": \"Clonidine\", \"type\": \"Chemical\"}, {\"text\": \"attention-deficit/hyperactivity disorder\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00424", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Although the transaminases gradually returned to baseline after withholding the beta lactam antibiotic, there was a gradual increase in serum bilirubin and a decrease in hemoglobin concentration caused by an autoimmune hemolytic anemia and erythroblastocytopenia.", "completion": "{\"entities\": [{\"text\": \"beta lactam\", \"type\": \"Chemical\"}, {\"text\": \"bilirubin\", \"type\": \"Chemical\"}, {\"text\": \"autoimmune hemolytic anemia\", \"type\": \"Disease\"}, {\"text\": \"erythroblastocytopenia\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01514", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Ketoconazole induced torsades de pointes without concomitant use of QT interval - prolonging drug.", "completion": "{\"entities\": [{\"text\": \"Ketoconazole\", \"type\": \"Chemical\"}, {\"text\": \"torsades de pointes\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04939", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: MATERIALS AND METHODS: Testosterone and prolactin were determined by radioimmunoassay.", "completion": "{\"entities\": [{\"text\": \"Testosterone\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03201", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Previously recognized side effects, particularly tremor and gastrointestinal problems, were more frequent in the mexiletine", "completion": "{\"entities\": [{\"text\": \"tremor\", \"type\": \"Disease\"}, {\"text\": \"gastrointestinal problems\", \"type\": \"Disease\"}, {\"text\": \"mexiletine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01915", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Those dosages (greater than or equal to 10 mg / kg) that inhibited mean NTE activity in the spinal cord greater than or equal to 73% and brain greater than or equal to 67% of control values produced severe (greater than or equal to 3) cervical cord pathology in 85% of the rats.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02647", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We report twin neonates who were born prematurely at 32 weeks of gestation to a mother with human immunodeficiency virus infection.", "completion": "{\"entities\": [{\"text\": \"human immunodeficiency virus infection\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02173", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Infusion started 15 min after injection of capsaicin.", "completion": "{\"entities\": [{\"text\": \"capsaicin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01113", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We describe the largest group of AX - allergic patients who have tolerated PG reported so far.", "completion": "{\"entities\": [{\"text\": \"AX\", \"type\": \"Chemical\"}, {\"text\": \"allergic\", \"type\": \"Disease\"}, {\"text\": \"PG\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00622", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These findings indicate that gabapentin has a measurable antinociceptive effect and a stronger antihyperalgesic effect most evident in the brain areas undergoing deactivation, thus supporting the concept that gabapentin", "completion": "{\"entities\": [{\"text\": \"gabapentin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00378", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Control chicks were in motion an average of 33.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03573", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The addition of ephedrine to propofol appears to be an effective method of obtunding the hypotensive response to propofol at all doses used in this study.", "completion": "{\"entities\": [{\"text\": \"ephedrine\", \"type\": \"Chemical\"}, {\"text\": \"propofol\", \"type\": \"Chemical\"}, {\"text\": \"hypotensive\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-05027", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After 6 weeks of therapy, glomerular filtration rate was not different among the studied groups.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03034", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 007) were significant predictors of outcome for the patients with cocaine - related aneurysms.", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"aneurysms\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02888", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These cases confirm the necessity of avoiding alcohol consumption as recommended in the instructions for use of Dormex", "completion": "{\"entities\": [{\"text\": \"alcohol\", \"type\": \"Chemical\"}, {\"text\": \"Dormex\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00118", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Labetalol administration was not associated with any of these findings.", "completion": "{\"entities\": [{\"text\": \"Labetalol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02601", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHOD: Twenty cocaine - dependent participants were randomly assigned to receive modafinil, 400 mg (N = 10 ), or placebo (N = 10) every morning at 7: 30 a.", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"modafinil\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00895", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Rabbit syndrome, antidepressant use, and cerebral perfusion SPECT scan findings.", "completion": "{\"entities\": [{\"text\": \"Rabbit syndrome\", \"type\": \"Disease\"}, {\"text\": \"antidepressant\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03849", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The fourth patient who was unconscious after chlormethiazole administration exhibite generalized non - reactive activity in the slow beta range.", "completion": "{\"entities\": [{\"text\": \"chlormethiazole\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03248", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 6% sevoflurane was not significant from that during 0.", "completion": "{\"entities\": [{\"text\": \"sevoflurane\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03294", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thirty minutes after 99mTc-glucarate administration the standardised heart uptake value S (h) UV was 4.", "completion": "{\"entities\": [{\"text\": \"99mTc-glucarate\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04261", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Immunohistochemical, electron microscopic and morphometric studies of estrogen - induced rat prolactinomas after bromocriptine treatment.", "completion": "{\"entities\": [{\"text\": \"estrogen\", \"type\": \"Chemical\"}, {\"text\": \"prolactinomas\", \"type\": \"Disease\"}, {\"text\": \"bromocriptine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00899", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Acute bronchodilating effects of ipratropium bromide and theophylline in chronic obstructive pulmonary disease.", "completion": "{\"entities\": [{\"text\": \"ipratropium bromide\", \"type\": \"Chemical\"}, {\"text\": \"theophylline\", \"type\": \"Chemical\"}, {\"text\": \"chronic obstructive pulmonary disease\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04033", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Of the remainder, 48 were possibly related to treatment, five were unlikely to be so, and six were unclassifiable.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02637", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Permeability was assessed using isolated kidney perfusion with tracers.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00644", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The patient cohort (14 men, 11 women) was treated with SRL as conversion therapy, due to chronic allograft nephropathy (CAN )(n = 15) neoplasia (n = 8 ); Kaposi's sarcoma, Four skin cancers, One intestinal tumors, One renal cell carsinom) or BK virus nephropathy (n = 2 ). SRL was started at a mean of 78 +/- 42 (15 to 163) months after transplantation.", "completion": "{\"entities\": [{\"text\": \"SRL\", \"type\": \"Chemical\"}, {\"text\": \"chronic allograft nephropathy\", \"type\": \"Disease\"}, {\"text\": \"nephropathy\", \"type\": \"Disease\"}, {\"text\": \"CAN\", \"type\": \"Disease\"}, {\"text\": \"neoplasia\", \"type\": \"Disease\"}, {\"text\": \"Kaposi's sarcoma\", \"type\": \"Disease\"}, {\"text\": \"skin cancers\", \"type\": \"Disease\"}, {\"text\": \"intestinal tumors\", \"type\": \"Disease\"}, {\"text\": \"renal cell carsinom\", \"type\": \"Disease\"}]}", "n_entities": 9}
{"ref": "bc5cdr-train-02342", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Valproate - induced encephalopathy is a rare syndrome that may manifest in otherwise normal epileptic individuals.", "completion": "{\"entities\": [{\"text\": \"Valproate\", \"type\": \"Chemical\"}, {\"text\": \"encephalopathy\", \"type\": \"Disease\"}, {\"text\": \"epileptic\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02278", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 17beta-Estradiol did not alter the onset of first clonus in ovariectomized rats but accelerated it in males.", "completion": "{\"entities\": [{\"text\": \"17beta-Estradiol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02825", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The convulsant activity of bupivacaine was not significantly modified but calcium channel blockers decreased the time of latency to obtain bupivacaine - induced convulsions; this effect was less pronounced with bepridil", "completion": "{\"entities\": [{\"text\": \"bupivacaine\", \"type\": \"Chemical\"}, {\"text\": \"calcium\", \"type\": \"Chemical\"}, {\"text\": \"convulsions\", \"type\": \"Disease\"}, {\"text\": \"bepridil\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01615", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In addition to genetic influences, recent studies suggest that prenatal drug or chemical exposures are risk factors for autism.", "completion": "{\"entities\": [{\"text\": \"autism\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01069", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A prospective, randomized study was conducted to evaluate the role of vitamin B12 and folinic acid supplementation in preventing zidovudine (ZDV )- induced bone marrow suppression.", "completion": "{\"entities\": [{\"text\": \"vitamin B12\", \"type\": \"Chemical\"}, {\"text\": \"folinic acid\", \"type\": \"Chemical\"}, {\"text\": \"zidovudine\", \"type\": \"Chemical\"}, {\"text\": \"ZDV\", \"type\": \"Chemical\"}, {\"text\": \"bone marrow suppression\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-04332", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05 ). Our results suggest that addition of phenylephrine to nitroglycerin is not beneficial in the treatment of patients with acute myocardial infarction", "completion": "{\"entities\": [{\"text\": \"phenylephrine\", \"type\": \"Chemical\"}, {\"text\": \"nitroglycerin\", \"type\": \"Chemical\"}, {\"text\": \"acute myocardial infarction\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01363", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05 ), which was comparable to the percent reduction in glomeruli measured at 3 weeks of age.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02462", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Concomitant IS consisted of mycophenolate mofetil +/- steroids.", "completion": "{\"entities\": [{\"text\": \"mycophenolate mofetil\", \"type\": \"Chemical\"}, {\"text\": \"steroids\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03526", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Using linear regression we found that no correlation exists between seizure duration, elevation of phenytoin serum levels and cerebellar volume.", "completion": "{\"entities\": [{\"text\": \"seizure\", \"type\": \"Disease\"}, {\"text\": \"phenytoin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01159", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Histologic changes were found in rat kidneys after administration of MTX, CY and NG, while no such change was observed after 5-FU and joint administration of MTX + 5-FU + CY compared to controls.", "completion": "{\"entities\": [{\"text\": \"MTX\", \"type\": \"Chemical\"}, {\"text\": \"CY\", \"type\": \"Chemical\"}, {\"text\": \"NG\", \"type\": \"Chemical\"}, {\"text\": \"5-FU\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00722", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 64) as compared to isolated - HIT patients who did not develop thrombosis (0.", "completion": "{\"entities\": [{\"text\": \"HIT\", \"type\": \"Disease\"}, {\"text\": \"thrombosis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04671", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 8 %) than at 2 h after treatment with ergotamine / caffeine (38.", "completion": "{\"entities\": [{\"text\": \"ergotamine\", \"type\": \"Chemical\"}, {\"text\": \"caffeine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02823", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The convulsant activity, the time of latency to convulse and the mortality rate were assessed in each group.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00471", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Although the explanation for the association between artery calcification and growth status cannot be determined from the present study, there was a relationship between higher serum phosphate and susceptibility to artery calcification, with 30% higher levels of serum phosphate in young, ad libitum - fed rats compared with either of the groups that was resistant to Warfarin - induced artery calcification, ie, the 10 - month - old rats and the restricted - diet, growth - inhibited young rats.", "completion": "{\"entities\": [{\"text\": \"artery calcification\", \"type\": \"Disease\"}, {\"text\": \"phosphate\", \"type\": \"Chemical\"}, {\"text\": \"Warfarin\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03805", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: NRA0160 is over 20, 000fold more potent at the dopamine D4.", "completion": "{\"entities\": [{\"text\": \"NRA0160\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04170", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5% bupivacaine in 7.", "completion": "{\"entities\": [{\"text\": \"bupivacaine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-reassigned-02571", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 3 micrograms) and atenolol (7.", "completion": "{\"entities\": [{\"text\": \"atenolol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01529", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Similarly, significant improvements in memory scores were observed using passive avoidance apparatus and aged mice.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02324", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In SE survivors, similar stimulation resulted in a population spike followed, at a variable latency, by negative DC shifts and repetitive afterdischarges of 3 - 60 s duration, which were blocked by ionotropic glutamate receptor antagonists.", "completion": "{\"entities\": [{\"text\": \"SE\", \"type\": \"Disease\"}, {\"text\": \"glutamate\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04743", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Six of 61 women (10 %) developed clinically reversible grade 3 CHF following infusional cyclophosphamide with a median percent decline in ejection fraction of 31 %. Incidence of transient cyclophosphamide - related cardiac toxicity (10 %) is comparable to previous recorded literature.", "completion": "{\"entities\": [{\"text\": \"CHF\", \"type\": \"Disease\"}, {\"text\": \"cyclophosphamide\", \"type\": \"Chemical\"}, {\"text\": \"cardiac toxicity\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01731", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: Neonatal rats were treated with the tricyclic antidepressant clomipramine or vehicle between days 9 and 16 twice daily and behaviorally tested in adulthood.", "completion": "{\"entities\": [{\"text\": \"antidepressant\", \"type\": \"Chemical\"}, {\"text\": \"clomipramine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04645", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSION: This case started with a media report in a popular newspaper, initiated by published, peer - reviewed research on herbals, and involved human failure in a case history, medical examination and clinical treatment.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00486", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: antidepressant drugs and, more particularly, selective serotonin reuptake inhibitors [SSRIs ]), use and type of mood stabilizers (lithium vs.", "completion": "{\"entities\": [{\"text\": \"antidepressant\", \"type\": \"Chemical\"}, {\"text\": \"serotonin reuptake inhibitors\", \"type\": \"Chemical\"}, {\"text\": \"SSRIs\", \"type\": \"Chemical\"}, {\"text\": \"lithium\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02017", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: From these data we conclude that the penile pain", "completion": "{\"entities\": [{\"text\": \"penile pain\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04597", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: To develop a more sensitive echocardiographic screening test for cardiac damage due to doxorubicin, a cohort study was performed using dobutamine infusion to differentiate asymptomatic long - term survivors of childhood cancer treated with doxorubicin from healthy control subjects.", "completion": "{\"entities\": [{\"text\": \"cardiac damage\", \"type\": \"Disease\"}, {\"text\": \"doxorubicin\", \"type\": \"Chemical\"}, {\"text\": \"dobutamine\", \"type\": \"Chemical\"}, {\"text\": \"cancer\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01408", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 17 (X +/- SE ). The development of severe anemia at 6 months post - CAB was predictable by the reduction of Hb baseline value of more than 2.", "completion": "{\"entities\": [{\"text\": \"anemia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04321", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Reversal by phenylephrine of the beneficial effects of intravenous nitroglycerin in patients with acute myocardial infarction.", "completion": "{\"entities\": [{\"text\": \"phenylephrine\", \"type\": \"Chemical\"}, {\"text\": \"nitroglycerin\", \"type\": \"Chemical\"}, {\"text\": \"acute myocardial infarction\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00860", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Hypertensive patients with psychiatric histories had a higher prevalence of depression than the comparison patients.", "completion": "{\"entities\": [{\"text\": \"Hypertensive\", \"type\": \"Disease\"}, {\"text\": \"psychiatric\", \"type\": \"Disease\"}, {\"text\": \"depression\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01521", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pharmacological evidence for the potential of Daucus carota in the management of cognitive dysfunctions.", "completion": "{\"entities\": [{\"text\": \"cognitive dysfunctions\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01188", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Upregulation of the expression of vasopressin gene in the paraventricular and supraoptic nuclei of the lithium - induced diabetes insipidus rat.", "completion": "{\"entities\": [{\"text\": \"vasopressin\", \"type\": \"Chemical\"}, {\"text\": \"lithium\", \"type\": \"Chemical\"}, {\"text\": \"diabetes insipidus\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00083", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: An experimental study / short communication.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02423", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the present study, we investigated whether maltolyl p-coumarate could improve cognitive decline in scopolamine - injected rats and in amyloid beta peptide(1-42) - infused rats.", "completion": "{\"entities\": [{\"text\": \"maltolyl p-coumarate\", \"type\": \"Chemical\"}, {\"text\": \"cognitive decline\", \"type\": \"Disease\"}, {\"text\": \"scopolamine\", \"type\": \"Chemical\"}, {\"text\": \"amyloid beta peptide(1-42)\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02802", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The mean doses of MZ and FL were 4.", "completion": "{\"entities\": [{\"text\": \"MZ\", \"type\": \"Chemical\"}, {\"text\": \"FL\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04320", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The fits ceased within 4 hours of administering intramuscular pyridoxine, suggesting an aetiology of pyridoxine deficiency secondary to isoniazid", "completion": "{\"entities\": [{\"text\": \"fits\", \"type\": \"Disease\"}, {\"text\": \"pyridoxine\", \"type\": \"Chemical\"}, {\"text\": \"isoniazid\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01115", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Persistent paralysis after prolonged use of atracurium in the absence of corticosteroids.", "completion": "{\"entities\": [{\"text\": \"paralysis\", \"type\": \"Disease\"}, {\"text\": \"atracurium\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-02763", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Control patients received infusions of 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03624", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These observations support the hypothesis that treatment with high doses of D-pen", "completion": "{\"entities\": [{\"text\": \"D-pen\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01454", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: for 2 days at an interval of 24 h ). TCR prevented the isoproterenol - induced decrease in antioxidant enzymes in the heart and increased the rate of ADP - stimulated oxygen uptake and respiratory coupling ratio.", "completion": "{\"entities\": [{\"text\": \"TCR\", \"type\": \"Chemical\"}, {\"text\": \"isoproterenol\", \"type\": \"Chemical\"}, {\"text\": \"ADP\", \"type\": \"Chemical\"}, {\"text\": \"oxygen\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03212", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Epinephrine has a proven role in cardiac arrest in prehospital care; however, use by paramedics in patients with suspected allergic reaction and severe hypertension", "completion": "{\"entities\": [{\"text\": \"Epinephrine\", \"type\": \"Chemical\"}, {\"text\": \"cardiac arrest\", \"type\": \"Disease\"}, {\"text\": \"allergic reaction\", \"type\": \"Disease\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02830", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The aims of this study were to confirm our previous findings in a separate cohort of patients and to determine the time course of the cardiovascular consequences of stopping selegiline in the expectation that this might shed light on the mechanisms by which the drug causes orthostatic hypotension.", "completion": "{\"entities\": [{\"text\": \"selegiline\", \"type\": \"Chemical\"}, {\"text\": \"orthostatic hypotension\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01844", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 8% of deaths among the patients, whereas it was the 5th most common cause of death among the Japanese general population in 1985.", "completion": "{\"entities\": [{\"text\": \"death\", \"type\": \"Disease\"}, {\"text\": \"deaths\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03352", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Methamphetamine (10 mg / kg sc ), administered five times, reduced the levels of dopamine and its metabolites in striatal tissue when measured 72 h after the last injection.", "completion": "{\"entities\": [{\"text\": \"Methamphetamine\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00071", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The data indicate that audiovisual toxicity is not an infrequent complication in hemodialyzed patients receiving desferrioxamine", "completion": "{\"entities\": [{\"text\": \"audiovisual toxicity\", \"type\": \"Disease\"}, {\"text\": \"desferrioxamine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02871", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In a placebo - controlled, single - blinded, crossover study, we assessed the effect of\" real\" repetitive transcranial magnetic stimulation (rTMS) versus\" sham\" rTMS (placebo) on peak dose dyskinesias in patients with Parkinson's disease (PD ). Ten patients with PD and prominent dyskinesias had rTMS (1, 800 pulses; 1 Hz rate) delivered over the motor cortex for 4 consecutive days twice, once real stimuli and once sham stimulation were used; evaluations were done at the baseline and 1 day after the end of each of the treatment series.", "completion": "{\"entities\": [{\"text\": \"dyskinesias\", \"type\": \"Disease\"}, {\"text\": \"Parkinson's disease\", \"type\": \"Disease\"}, {\"text\": \"PD\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01893", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Use of verapamil in combination with carbamazepine should either be avoided or prescribed only with appropriate adjustment of the carbamazepine dose (usually reduction of the carbamazepine", "completion": "{\"entities\": [{\"text\": \"verapamil\", \"type\": \"Chemical\"}, {\"text\": \"carbamazepine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01523", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The ethanolic extract of Daucus carota seeds (DCE) was administered orally in three doses (100, 200, 400 mg / kg) for seven successive days to different groups of young and aged mice.", "completion": "{\"entities\": [{\"text\": \"extract of Daucus carota seeds\", \"type\": \"Chemical\"}, {\"text\": \"DCE\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02193", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Due to severe systolic dysfunction losartan was prescribed.", "completion": "{\"entities\": [{\"text\": \"systolic dysfunction\", \"type\": \"Disease\"}, {\"text\": \"losartan\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01773", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The most common primary tumor site was the head and neck.", "completion": "{\"entities\": [{\"text\": \"tumor\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03176", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Examinations, including blood pressure, pulse rate, conjunctiva and cornea, intraocular pressure (IOP ), pupil diameter, basal tear secretion and margin reflex distance of both upper and lower eyelids, were performed prior to entry and at 1, 3, 5 and 7 hours after instillation.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03784", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In four subacute toxicity studies, the intravenous administration of cefonicid or cefazedone to beagle dogs caused a dose - dependent incidence of anemia, neutropenia, and thrombocytopenia after 1 - 3 months of treatment.", "completion": "{\"entities\": [{\"text\": \"toxicity\", \"type\": \"Disease\"}, {\"text\": \"cefonicid\", \"type\": \"Chemical\"}, {\"text\": \"cefazedone\", \"type\": \"Chemical\"}, {\"text\": \"anemia\", \"type\": \"Disease\"}, {\"text\": \"neutropenia\", \"type\": \"Disease\"}, {\"text\": \"thrombocytopenia\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-00676", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In both types, purinoceptor desensitization with alpha,beta-methylene adenosine-5'-triphosphate (alpha,beta-meATP) caused further reductions at low frequencies (< 10 Hz ). The muscarinic receptor antagonists atropine, 4-diphenylacetoxy-N-methylpiperidine (4-DAMP )(' M (1 )/ M (3 )/ M (5 )- selective '), methoctramine (' M (2 )- selective ') and pirenzepine (' M (1 )- selective ') antagonized the tonic component of the electrical field stimulation - evoked contractile response more potently than the phasic component.", "completion": "{\"entities\": [{\"text\": \"alpha,beta-methylene adenosine-5'-triphosphate\", \"type\": \"Chemical\"}, {\"text\": \"alpha,beta-meATP\", \"type\": \"Chemical\"}, {\"text\": \"atropine\", \"type\": \"Chemical\"}, {\"text\": \"4-diphenylacetoxy-N-methylpiperidine\", \"type\": \"Chemical\"}, {\"text\": \"4-DAMP\", \"type\": \"Chemical\"}, {\"text\": \"methoctramine\", \"type\": \"Chemical\"}, {\"text\": \"pirenzepine\", \"type\": \"Chemical\"}]}", "n_entities": 7}
{"ref": "bc5cdr-train-03528", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We conclude that phenytoin overdosage does not necessarily result in cerebellar atrophy and it is unlikely that phenytoin medication was the only cause of cerebellar atrophy in the remaining patients.", "completion": "{\"entities\": [{\"text\": \"phenytoin\", \"type\": \"Chemical\"}, {\"text\": \"overdosage\", \"type\": \"Disease\"}, {\"text\": \"cerebellar atrophy\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00930", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 degrees C) enhanced both Adriamycin - mediated antitumor activity and toxic side effects.", "completion": "{\"entities\": [{\"text\": \"Adriamycin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04793", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: NFkappaB activity was decreased in the frontal cortex of cocaine treated rats, as well as GSH concentration and glutathione peroxidase activity in the hippocampus, whereas nNOS activity in the hippocampus was increased.", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"GSH\", \"type\": \"Chemical\"}, {\"text\": \"glutathione\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00633", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thirty minutes from the start of the procedure, the donor noted tingling around the mouth, hands, and feet.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-05149", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Data were analysed using chi - square test, Mann - Whitney U, Wilcoxon signed ranks tests and correlation.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-reassigned-03705", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Viracept and irregular heartbeat warning.", "completion": "{\"entities\": [{\"text\": \"Viracept\", \"type\": \"Chemical\"}, {\"text\": \"irregular heartbeat\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03793", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Periodic withdrawal of pyridoxine was associated with return of the hyperkinesis.", "completion": "{\"entities\": [{\"text\": \"pyridoxine\", \"type\": \"Chemical\"}, {\"text\": \"hyperkinesis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01569", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Sirolimus - associated proteinuria and renal dysfunction.", "completion": "{\"entities\": [{\"text\": \"Sirolimus\", \"type\": \"Chemical\"}, {\"text\": \"proteinuria\", \"type\": \"Disease\"}, {\"text\": \"renal dysfunction\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00329", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This case study reveals an unusual finding of rapidly proliferative crescentic glomerulonephritis in a patient treated with rifampin who had no other identifiable causes for developing this disease.", "completion": "{\"entities\": [{\"text\": \"glomerulonephritis\", \"type\": \"Disease\"}, {\"text\": \"rifampin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03546", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A significant rise in cTnT was found in DOX rats after cumulative doses of 7.", "completion": "{\"entities\": [{\"text\": \"DOX\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01869", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Intracranial pressure (ICP) was measured during alfentanil - induced rigidity in rats.", "completion": "{\"entities\": [{\"text\": \"alfentanil\", \"type\": \"Chemical\"}, {\"text\": \"rigidity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01983", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The effect of amiloride on lithium - induced polydipsia and polyuria and on the lithium concentration in the plasma, brain, kidney, thyroid and red blood cells was investigated in rats, chronically treated with LiCl.", "completion": "{\"entities\": [{\"text\": \"amiloride\", \"type\": \"Chemical\"}, {\"text\": \"lithium\", \"type\": \"Chemical\"}, {\"text\": \"polydipsia\", \"type\": \"Disease\"}, {\"text\": \"polyuria\", \"type\": \"Disease\"}, {\"text\": \"LiCl\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-00567", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The time courses of urinary sodium excretion, plasma aldosterone concentration and proteinuria were studied in male Sprague - Dawley rats treated with a single dose of either PAN or vehicle.", "completion": "{\"entities\": [{\"text\": \"sodium\", \"type\": \"Chemical\"}, {\"text\": \"aldosterone\", \"type\": \"Chemical\"}, {\"text\": \"proteinuria\", \"type\": \"Disease\"}, {\"text\": \"PAN\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04589", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Effect of direct intracoronary administration of methylergonovine in patients with and without variant angina.", "completion": "{\"entities\": [{\"text\": \"methylergonovine\", \"type\": \"Chemical\"}, {\"text\": \"variant angina\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00148", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: On the first day of the schedule, moderate high doses of Methotrexate, Etoposide and Cyclophosphamide were administered.", "completion": "{\"entities\": [{\"text\": \"Methotrexate\", \"type\": \"Chemical\"}, {\"text\": \"Etoposide\", \"type\": \"Chemical\"}, {\"text\": \"Cyclophosphamide\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01037", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: When the metoclopramide administration was discontinued, the abnormal movements gradually improved to a considerable extent.", "completion": "{\"entities\": [{\"text\": \"metoclopramide\", \"type\": \"Chemical\"}, {\"text\": \"abnormal movements\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00462", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Therefore the prophylactic use of granulocyte - colony stimulating factor should be considered with this treatment.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04728", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 mg / kg ip) and a relatively specific inhibitor of neuronal NO synthase (7 - NI; 0.", "completion": "{\"entities\": [{\"text\": \"NO\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03229", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Replication - competent HBV strains with sG145R or sP120T and LAM resistance (rtM204I or rtL180M / rtM204V) were generated on an HBeAg - positive and an HBeAg - negative background with precore (PC) and basal core promoter (BCP) mutants.", "completion": "{\"entities\": [{\"text\": \"LAM\", \"type\": \"Chemical\"}, {\"text\": \"HBeAg\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-02086", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Bradycardia due to biperiden.", "completion": "{\"entities\": [{\"text\": \"Bradycardia\", \"type\": \"Disease\"}, {\"text\": \"biperiden\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02110", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This is a case report of euphoria and choreoathetoid movements both transiently induced by rapid adjustment to the selective mu - opioid receptor agonist methadone in an inpatient previously abusing heroine and cocaine", "completion": "{\"entities\": [{\"text\": \"choreoathetoid movements\", \"type\": \"Disease\"}, {\"text\": \"methadone\", \"type\": \"Chemical\"}, {\"text\": \"heroine\", \"type\": \"Chemical\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03855", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND AND OBJECTIVE: Despite advantages of induction and maintenance of anaesthesia with sevoflurane, postoperative nausea and vomiting occurs frequently.", "completion": "{\"entities\": [{\"text\": \"sevoflurane\", \"type\": \"Chemical\"}, {\"text\": \"postoperative nausea and vomiting\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00165", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The pentose phosphate shunt activity of the dapsone - exposed AE RBCs was increased compared to normal RBCs.", "completion": "{\"entities\": [{\"text\": \"pentose phosphate\", \"type\": \"Chemical\"}, {\"text\": \"dapsone\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01850", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A reversible anemia was the only adverse effect observed.", "completion": "{\"entities\": [{\"text\": \"anemia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00878", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pimozide did not affect the actions of L-dopa on blood pressure and heart rate but completely blocked the enhancement of reflexes.", "completion": "{\"entities\": [{\"text\": \"Pimozide\", \"type\": \"Chemical\"}, {\"text\": \"L-dopa\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00819", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: At presentation, advanced encephalopathy and cerebral edema were present in 51 (76 %) and 29 (41.", "completion": "{\"entities\": [{\"text\": \"encephalopathy\", \"type\": \"Disease\"}, {\"text\": \"cerebral edema\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05063", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The study suggests that the activity - increasing effects of morphine are mediated by the release of catecholamines from adrenergic neurons in the brain.", "completion": "{\"entities\": [{\"text\": \"morphine\", \"type\": \"Chemical\"}, {\"text\": \"catecholamines\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05087", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: better, in patients on bupropion SR, at 2.", "completion": "{\"entities\": [{\"text\": \"bupropion\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-reassigned-04225", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 338 unpaired t - test.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03111", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CASE REPORT: We describe 2 patients who were regular consumers of alcohol and who developed liver failure within 3 - 5 days after hospitalization and stopping alcohol consumption while being treated with 4 g paracetamol / day.", "completion": "{\"entities\": [{\"text\": \"alcohol\", \"type\": \"Chemical\"}, {\"text\": \"liver failure\", \"type\": \"Disease\"}, {\"text\": \"paracetamol\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00600", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, the behavioral effects of centrally administered U-II have received little attention.", "completion": "{\"entities\": [{\"text\": \"U-II\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00435", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Tetrandrine (TET) and fangchinoline (FAN) are two naturally occurring analogues with a bisbenzylisoquinoline structure.", "completion": "{\"entities\": [{\"text\": \"Tetrandrine\", \"type\": \"Chemical\"}, {\"text\": \"TET\", \"type\": \"Chemical\"}, {\"text\": \"fangchinoline\", \"type\": \"Chemical\"}, {\"text\": \"FAN\", \"type\": \"Chemical\"}, {\"text\": \"bisbenzylisoquinoline\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-reassigned-01572", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Some observations in adults.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00640", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Proteinuria after conversion to sirolimus in renal transplant recipients.", "completion": "{\"entities\": [{\"text\": \"Proteinuria\", \"type\": \"Disease\"}, {\"text\": \"sirolimus\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00468", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In contrast, no artery calcification could be detected in 10 - month - old adult rats even after 4 weeks of Warfarin treatment.", "completion": "{\"entities\": [{\"text\": \"artery calcification\", \"type\": \"Disease\"}, {\"text\": \"Warfarin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00426", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Despite the widespread use of these agents this triad of side effects has not previously been reported in connection with beta lactam", "completion": "{\"entities\": [{\"text\": \"beta lactam\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01759", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Evidence of microscopic damage was graded as less severe in the three treatment groups.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04892", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Fewer than 6% of patients in either group were considered by the investigator to have a worsening of their overall disease condition during the study.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02043", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Fragments of necrotic endothelial cells were in the vascular lumens and in these there was loosening and breaking of tight cellular junctions.", "completion": "{\"entities\": [{\"text\": \"necrotic\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01524", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Elevated plus maze and passive avoidance apparatus served as the exteroceptive behavioral models for testing memory.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04406", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Estrogen prevents cholesteryl ester accumulation in macrophages induced by the HIV protease inhibitor ritonavir.", "completion": "{\"entities\": [{\"text\": \"cholesteryl ester\", \"type\": \"Chemical\"}, {\"text\": \"ritonavir\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03337", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 22, NS ). In controls, no predictive values for renal parameters were observed.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02137", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Inhibition of NO synthesis induces sustained hypertension.", "completion": "{\"entities\": [{\"text\": \"NO\", \"type\": \"Chemical\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04498", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05 ). Systolic blood pressure was elevated by an average of 7 mm Hg.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01249", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 4) for switchers from second to third generation pills relative to switchers from third to second generation pills.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01420", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Organophosphate - induced convulsions and prevention of neuropathological damages.", "completion": "{\"entities\": [{\"text\": \"Organophosphate\", \"type\": \"Chemical\"}, {\"text\": \"convulsions\", \"type\": \"Disease\"}, {\"text\": \"neuropathological damages\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01515", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Ketoconazole is not known to be proarrhythmic without concomitant use of QT interval - prolonging drugs.", "completion": "{\"entities\": [{\"text\": \"Ketoconazole\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00499", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Here, 2 cases of urinary bladder retention leading to renal pelvocalyceal dilatation mimicking hydronephrosis as a result of continuous infusion of fentanyl", "completion": "{\"entities\": [{\"text\": \"urinary bladder retention\", \"type\": \"Disease\"}, {\"text\": \"hydronephrosis\", \"type\": \"Disease\"}, {\"text\": \"fentanyl\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03372", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Proteomic analysis of striatal proteins in the rat model of L-DOPA - induced dyskinesia.", "completion": "{\"entities\": [{\"text\": \"L-DOPA\", \"type\": \"Chemical\"}, {\"text\": \"dyskinesia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01727", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 3 l min (- 1 )), and preserved S (c) O (2 ). CONCLUSIONS: The utilization of phenylephrine to correct hypotension induced by anesthesia has a negative impact on S (c) O (2) while ephedrine", "completion": "{\"entities\": [{\"text\": \"phenylephrine\", \"type\": \"Chemical\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}, {\"text\": \"ephedrine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00906", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: While side effects were rare, those experienced after theophylline use did involve the cardiovascular and gastrointestinal systems.", "completion": "{\"entities\": [{\"text\": \"theophylline\", \"type\": \"Chemical\"}, {\"text\": \"cardiovascular and gastrointestinal systems\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00859", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The results showed a high prevalence of depression in both groups of patients, with no preponderance in the hypertensive group.", "completion": "{\"entities\": [{\"text\": \"depression\", \"type\": \"Disease\"}, {\"text\": \"hypertensive\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01170", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Combination chemotherapy with mitoxantrone, high - dose 5-fluorouracil (5-FU) and leucovorin (MFL regimen) had been reported as an effective and well tolerated regimen.", "completion": "{\"entities\": [{\"text\": \"mitoxantrone\", \"type\": \"Chemical\"}, {\"text\": \"5-fluorouracil\", \"type\": \"Chemical\"}, {\"text\": \"5-FU\", \"type\": \"Chemical\"}, {\"text\": \"leucovorin\", \"type\": \"Chemical\"}, {\"text\": \"MFL regimen\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-00404", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Immunohistochemistry with monoclonal antibodies against neurofilament (NF) proteins of middle and high molecular weight class, NF - M and NF - H, was used to study axonal injury in the borderzone of focal lesions in rats.", "completion": "{\"entities\": [{\"text\": \"axonal injury\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04835", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Certain clues, including the onset of action, seem to be indicative of the superiority of bromperidol", "completion": "{\"entities\": [{\"text\": \"bromperidol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02548", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: Topical papaverine for the treatment of vasospasm was associated with the onset of a transient disturbance in neurophysiological function of the ascending auditory brainstem pathway.", "completion": "{\"entities\": [{\"text\": \"papaverine\", \"type\": \"Chemical\"}, {\"text\": \"vasospasm\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01800", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Previous reports have suggested that pain associated with the injection of lidocaine is related to the acidic pH of the solution.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"lidocaine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03474", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 35 mM Ca (N ). It decreased by 16 +/- 3% by lowering [Na] o to 78 mM (LNa ), 23 +/- 2% by lowering simultaneously [Na] o to 78 mM and [Ca] o to 0.", "completion": "{\"entities\": [{\"text\": \"Ca\", \"type\": \"Chemical\"}, {\"text\": \"Na\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01549", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: There was a decrease in the perception of pinprick test.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01362", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Offspring of rats administered dexamethasone on days 15 and 16 gestation had a 20% reduction in glomerular number compared with control at 6 to 9 months of age (22 527 +/- 509 versus 28 050 +/- 561, P < 0.", "completion": "{\"entities\": [{\"text\": \"dexamethasone\", \"type\": \"Chemical\"}, {\"text\": \"reduction in glomerular number\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03451", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSION: The findings are indicative of DFO' s contributing role in the development of hearing impairment.", "completion": "{\"entities\": [{\"text\": \"DFO\", \"type\": \"Chemical\"}, {\"text\": \"hearing impairment\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-02677", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the group that received 1.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01718", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05) followed with no change in CO (3.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02891", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The mechanism of its antidepressant activity is still unknown.", "completion": "{\"entities\": [{\"text\": \"antidepressant\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01323", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: One hundred patients were enrolled.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00695", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, use of BZDs / RDs was associated with dizziness, inability to sleep after awaking at night and tiredness in the mornings during the week prior to admission and with stronger depressive symptoms measured at the beginning of the hospital stay.", "completion": "{\"entities\": [{\"text\": \"BZDs\", \"type\": \"Chemical\"}, {\"text\": \"dizziness\", \"type\": \"Disease\"}, {\"text\": \"inability to sleep\", \"type\": \"Disease\"}, {\"text\": \"tiredness\", \"type\": \"Disease\"}, {\"text\": \"depressive symptoms\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-02842", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05, 1 and 20 microg, separated by 15 min breaks ), each given three times in a balanced design across three sessions at one week intervals.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04147", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: Patients with a clinical diagnosis of ischemic stroke (within 24 hours) were consecutively allocated to receive placebo (n = 100 ), 1 mg / h (low - dose) nimodipine (n = 101 ), or 2 mg / h (high - dose) nimodipine (n = 94 ). The correlation between average BP change during the first 2 days and the outcome at day 21 was analyzed.", "completion": "{\"entities\": [{\"text\": \"ischemic stroke\", \"type\": \"Disease\"}, {\"text\": \"nimodipine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00938", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Prazosin - induced stress incontinence.", "completion": "{\"entities\": [{\"text\": \"Prazosin\", \"type\": \"Chemical\"}, {\"text\": \"stress incontinence\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04805", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The antinociception produced by (+/-)- PG-9 was prevented by the unselective muscarinic antagonist atropine, the M1 - selective antagonists pirenzepine and dicyclomine and the acetylcholine depletor hemicholinium-3, but not by the opioid antagonist naloxone, the gamma-aminobutyric acidB antagonist 3-aminopropyl-diethoxy-methyl-phosphinic acid, the H3 agonist R-(alpha)-methylhistamine, the D2 antagonist quinpirole, the 5-hydroxytryptamine4 antagonist 2-methoxy-4-amino-5-chlorobenzoic acid 2-(diethylamino)ethyl ester hydrochloride, the 5-hydroxytryptamin1A antagonist 1-(2-methoxyphenyl)-4-[4-(2-phthalimido)butyl]piperazine hydrobromide and the polyamines depletor reserpine.", "completion": "{\"entities\": [{\"text\": \"PG-9\", \"type\": \"Chemical\"}, {\"text\": \"atropine\", \"type\": \"Chemical\"}, {\"text\": \"pirenzepine\", \"type\": \"Chemical\"}, {\"text\": \"dicyclomine\", \"type\": \"Chemical\"}, {\"text\": \"acetylcholine\", \"type\": \"Chemical\"}, {\"text\": \"hemicholinium-3\", \"type\": \"Chemical\"}, {\"text\": \"naloxone\", \"type\": \"Chemical\"}, {\"text\": \"gamma-aminobutyric acidB\", \"type\": \"Chemical\"}, {\"text\": \"3-aminopropyl-diethoxy-methyl-phosphinic acid\", \"type\": \"Chemical\"}, {\"text\": \"R-(alpha)-methylhistamine\", \"type\": \"Chemical\"}, {\"text\": \"quinpirole\", \"type\": \"Chemical\"}, {\"text\": \"5-hydroxytryptamine4\", \"type\": \"Chemical\"}, {\"text\": \"2-methoxy-4-amino-5-chlorobenzoic acid 2-(diethylamino)ethyl ester\", \"type\": \"Chemical\"}, {\"text\": \"5-hydroxytryptamin1A\", \"type\": \"Chemical\"}, {\"text\": \"1-(2-methoxyphenyl)-4-[4-(2-phthalimido)butyl]piperazine\", \"type\": \"Chemical\"}, {\"text\": \"reserpine\", \"type\": \"Chemical\"}]}", "n_entities": 16}
{"ref": "bc5cdr-train-03687", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Most patients showed moderate to severe acute hepatitis or chronic active hepatitis with associated cholestasis.", "completion": "{\"entities\": [{\"text\": \"acute hepatitis\", \"type\": \"Disease\"}, {\"text\": \"chronic active hepatitis\", \"type\": \"Disease\"}, {\"text\": \"cholestasis\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03889", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: p .), per se did not cause catalepsy.", "completion": "{\"entities\": [{\"text\": \"catalepsy\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03943", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Patients with renal insufficiency", "completion": "{\"entities\": [{\"text\": \"renal insufficiency\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00050", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: There were no serious clinical side effects, but dose reduction was required in two patients because of nausea.", "completion": "{\"entities\": [{\"text\": \"nausea\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04274", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It is suggested that the drug acted in a selective and tissue - specific manner to enhance ribosomal RNA synthesis in the liver and depress such synthesis in the muscle.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02089", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The routine use of pethidine", "completion": "{\"entities\": [{\"text\": \"pethidine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00516", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: e ., desogestrel or gestodene) and second - generation (i.", "completion": "{\"entities\": [{\"text\": \"desogestrel\", \"type\": \"Chemical\"}, {\"text\": \"gestodene\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02588", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In 7 of the 28 patients there was a striking temporal association between the initiation of sirolimus and the development of nephrotic - range proteinuria.", "completion": "{\"entities\": [{\"text\": \"sirolimus\", \"type\": \"Chemical\"}, {\"text\": \"nephrotic\", \"type\": \"Disease\"}, {\"text\": \"proteinuria\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01342", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Use of antithymocyte globulin may be the optimal treatment of D-penicillamine - induced aplastic anemia", "completion": "{\"entities\": [{\"text\": \"antithymocyte globulin\", \"type\": \"Chemical\"}, {\"text\": \"D-penicillamine\", \"type\": \"Chemical\"}, {\"text\": \"aplastic anemia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01083", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Effect of switching carbamazepine to oxcarbazepine on the plasma levels of neuroleptics.", "completion": "{\"entities\": [{\"text\": \"carbamazepine\", \"type\": \"Chemical\"}, {\"text\": \"oxcarbazepine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02161", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Given that sympathetic neural dominance exhibits a similar developmental pattern, and given that clonidine induces sympathetic withdrawal and bradycardia, we hypothesized that clonidine' s developmental effects on cardiac rate and ultrasound production would mirror each other.", "completion": "{\"entities\": [{\"text\": \"clonidine\", \"type\": \"Chemical\"}, {\"text\": \"bradycardia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-00280", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 009) and visual hallucinations (PR = 0.", "completion": "{\"entities\": [{\"text\": \"visual hallucinations\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03276", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Endothelial function was assessed by acetylcholine - induced vasorelaxation and phenylephrine - induced vasoconstriction in aortic segments.", "completion": "{\"entities\": [{\"text\": \"acetylcholine\", \"type\": \"Chemical\"}, {\"text\": \"phenylephrine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01729", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: Current animal models of obsessive-compulsive disorder (OCD) typically involve acute, drug - induced symptom provocation or a genetic association with stereotypies or anxiety.", "completion": "{\"entities\": [{\"text\": \"obsessive-compulsive disorder\", \"type\": \"Disease\"}, {\"text\": \"OCD\", \"type\": \"Disease\"}, {\"text\": \"anxiety\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03975", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: Drugs were separately, orally once daily dosed to pregnant rats from day 8 to 21 (GD1 = plug day ). Doses were set at 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00058", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Sulpiride - induced tardive dystonia.", "completion": "{\"entities\": [{\"text\": \"Sulpiride\", \"type\": \"Chemical\"}, {\"text\": \"tardive dystonia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05014", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Flestolol blood concentrations increased linearly with increasing dose and good correlation exists between blood concentrations of flestolol and beta - adrenergic blockade.", "completion": "{\"entities\": [{\"text\": \"Flestolol\", \"type\": \"Chemical\"}, {\"text\": \"flestolol\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05136", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: By implantation of electrodes and electrophysiological recording in vivo, the results showed that Rg1 restored the long - term potentiation (LTP) impaired by morphine in both freely moving and anaesthetised rats.", "completion": "{\"entities\": [{\"text\": \"Rg1\", \"type\": \"Chemical\"}, {\"text\": \"morphine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00558", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The mechanisms of this ticlopidine - induced cholestasis are unclear.", "completion": "{\"entities\": [{\"text\": \"ticlopidine\", \"type\": \"Chemical\"}, {\"text\": \"cholestasis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03825", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Modest increases in HDL - cholesterol levels of about 10% are also reported.", "completion": "{\"entities\": [{\"text\": \"cholesterol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03605", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thus, use of FS containing tAMCA", "completion": "{\"entities\": [{\"text\": \"tAMCA\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03438", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Long term audiological evaluation of beta-thalassemic patients.", "completion": "{\"entities\": [{\"text\": \"beta-thalassemic\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02104", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In 8 patients the diagnosis of primary pulmonary hypertension was uncertain, 5 of them had taken appetite suppressants.", "completion": "{\"entities\": [{\"text\": \"primary pulmonary hypertension\", \"type\": \"Disease\"}, {\"text\": \"appetite suppressants\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03104", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Simultaneous measurements of ECG and brachial artery dP / dtejc were performed at each dobutamine level.", "completion": "{\"entities\": [{\"text\": \"dobutamine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01813", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Muscle strength, contractures, functional ability and pulmonary function were tested at baseline, and 6 and 12 months after treatment with mazindol (3 mg / d) or placebo.", "completion": "{\"entities\": [{\"text\": \"mazindol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03067", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Rabbit syndrome (RS) is a rare extrapyramidal side effect caused by prolonged neuroleptic medication.", "completion": "{\"entities\": [{\"text\": \"Rabbit syndrome\", \"type\": \"Disease\"}, {\"text\": \"RS\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00484", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Patients who experienced a manic or hypomanic switch were compared with those who did not on several variables including age, sex, diagnosis (DSM-IV bipolar I vs.", "completion": "{\"entities\": [{\"text\": \"manic\", \"type\": \"Disease\"}, {\"text\": \"hypomanic\", \"type\": \"Disease\"}, {\"text\": \"DSM-IV bipolar I\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-reassigned-04158", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Ethambutol and optic neuropathy.", "completion": "{\"entities\": [{\"text\": \"Ethambutol\", \"type\": \"Chemical\"}, {\"text\": \"optic neuropathy\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04545", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Mature male and female mice from six inbred stains were tested for susceptibility to behavioral seizures induced by a single injection of cocaine.", "completion": "{\"entities\": [{\"text\": \"seizures\", \"type\": \"Disease\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05012", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This agent was well tolerated in healthy volunteers at doses up to 100 micrograms / kg / min.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01644", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: In this study, we evaluated the performance of dopamine beta - hydroxylase knockout (Dbh -/-) mice, which lack norepinephrine (NE ), in the elevated plus maze (EPM) to examine the contribution of noradrenergic signaling to cocaine - induced anxiety.", "completion": "{\"entities\": [{\"text\": \"dopamine\", \"type\": \"Chemical\"}, {\"text\": \"norepinephrine\", \"type\": \"Chemical\"}, {\"text\": \"NE\", \"type\": \"Chemical\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"anxiety\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-05206", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We attempted to find underlying similarities, evaluate the risk factors, and identify appropriate treatment for this complication.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04999", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: should immediately precede induction of anaesthesia, in children, if the repeated administration of suxamethonium", "completion": "{\"entities\": [{\"text\": \"suxamethonium\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03065", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the absence of the carcinogen, 5-AzC", "completion": "{\"entities\": [{\"text\": \"5-AzC\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02126", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This was further evidenced by absence of oxygen consumption and hemoglobin oxidation both determined in parallel with TAM - induced hemolysis.", "completion": "{\"entities\": [{\"text\": \"oxygen\", \"type\": \"Chemical\"}, {\"text\": \"TAM\", \"type\": \"Chemical\"}, {\"text\": \"hemolysis\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01402", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Severe and clinically evident anemia of Hb < 11 g / dl with clinical symptoms was detected in 6 patients (14.", "completion": "{\"entities\": [{\"text\": \"anemia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05095", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 003 ), and in the five different domains of the IIEF.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04579", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The results suggest a strain - dependent effect of amantadine on motility and indicate a differential response to the acute and multiple dose regimens used.", "completion": "{\"entities\": [{\"text\": \"amantadine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01863", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Noradrenergic involvement in catalepsy induced by delta 9-tetrahydrocannabinol.", "completion": "{\"entities\": [{\"text\": \"catalepsy\", \"type\": \"Disease\"}, {\"text\": \"delta 9-tetrahydrocannabinol\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01424", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The rats received AChE reactivator pralidoxime-2-chloride (2PAM )(30.", "completion": "{\"entities\": [{\"text\": \"pralidoxime-2-chloride\", \"type\": \"Chemical\"}, {\"text\": \"2PAM\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04828", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The daily dose (initial dose: 1 mg; mean dose at the end of the trial: 4.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01427", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 mg / kg BW ), NMDA - receptor antagonist dizocilpine maleate (+- MK801 hydrogen maleate )(2.", "completion": "{\"entities\": [{\"text\": \"NMDA\", \"type\": \"Chemical\"}, {\"text\": \"dizocilpine maleate\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03834", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Sulfasalazine - induced lupus erythematosus.", "completion": "{\"entities\": [{\"text\": \"Sulfasalazine\", \"type\": \"Chemical\"}, {\"text\": \"lupus erythematosus\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00717", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: At diagnosis there was no significant difference in OD between HIT patients with thrombosis and those with isolated - HIT.", "completion": "{\"entities\": [{\"text\": \"HIT\", \"type\": \"Disease\"}, {\"text\": \"thrombosis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02250", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The administration of ifosfamide was discontinued and within 12 h the asterixis resolved completely.", "completion": "{\"entities\": [{\"text\": \"ifosfamide\", \"type\": \"Chemical\"}, {\"text\": \"asterixis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02395", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In 414 patients, contrast volume, presence of diabetes mellitus, use of N-acetylcysteine, mean baseline SCr, and estimated glomerular filtration rate were comparable in the 2 groups.", "completion": "{\"entities\": [{\"text\": \"diabetes mellitus\", \"type\": \"Disease\"}, {\"text\": \"N-acetylcysteine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01897", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: When deferoxamine therapy was discontinued and serial studies were performed, audiograms in seven cases reverted to normal or near normal within two to three weeks, and nine of 13 patients with symptoms became asymptomatic.", "completion": "{\"entities\": [{\"text\": \"deferoxamine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04231", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Of the 15 spinal cords of the animals that received 2-chloroprocaine-CE, 13 showed subpial necrosis; the nerve roots and subarachnoid vessels were normal.", "completion": "{\"entities\": [{\"text\": \"2-chloroprocaine-CE\", \"type\": \"Chemical\"}, {\"text\": \"subpial necrosis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00168", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thus, AE RBCs appear to have an increased sensitivity to oxidant stress both in vitro and in vivo, since dapsone does not cause hemolytic anemia at this dose in hematologically normal individuals.", "completion": "{\"entities\": [{\"text\": \"dapsone\", \"type\": \"Chemical\"}, {\"text\": \"hemolytic anemia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00945", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Patients who present with stress incontinence while taking prazosin should change their antihypertensive medication before considering surgery, because their incontinence", "completion": "{\"entities\": [{\"text\": \"stress incontinence\", \"type\": \"Disease\"}, {\"text\": \"incontinence\", \"type\": \"Disease\"}, {\"text\": \"prazosin\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02013", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: prostaglandin E1 with (pH 7.", "completion": "{\"entities\": [{\"text\": \"prostaglandin E1\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04419", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Treatment with E2, however, failed to prevent these increases at the mRNA level.", "completion": "{\"entities\": [{\"text\": \"E2\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03592", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, tAMCA has been shown to cause epileptic seizures.", "completion": "{\"entities\": [{\"text\": \"tAMCA\", \"type\": \"Chemical\"}, {\"text\": \"epileptic seizures\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04688", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Salvage therapy with nelarabine, etoposide, and cyclophosphamide in relapsed / refractory paediatric T-cell lymphoblastic leukaemia and lymphoma.", "completion": "{\"entities\": [{\"text\": \"nelarabine\", \"type\": \"Chemical\"}, {\"text\": \"etoposide\", \"type\": \"Chemical\"}, {\"text\": \"cyclophosphamide\", \"type\": \"Chemical\"}, {\"text\": \"T-cell lymphoblastic leukaemia and lymphoma\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03132", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: DISCUSSION: The risk of rhabdomyolysis is increased in the presence of concomitant drugs that inhibit simvastatin metabolism.", "completion": "{\"entities\": [{\"text\": \"rhabdomyolysis\", \"type\": \"Disease\"}, {\"text\": \"simvastatin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00877", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: FLA-63, a dopamine - beta - oxidase inhibitor, did not have any effect on the hypotension, bradycardia or reflex - enhancing effect of L-dopa.", "completion": "{\"entities\": [{\"text\": \"FLA-63\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}, {\"text\": \"bradycardia\", \"type\": \"Disease\"}, {\"text\": \"L-dopa\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-01912", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The correlation between neurotoxic esterase inhibition and mipafox - induced neuropathic damage in rats.", "completion": "{\"entities\": [{\"text\": \"neurotoxic\", \"type\": \"Disease\"}, {\"text\": \"mipafox\", \"type\": \"Chemical\"}, {\"text\": \"neuropathic damage\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00856", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSION: Activation of pallidal neurotensin receptors may be involved in neurotensin", "completion": "{\"entities\": [{\"text\": \"neurotensin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03627", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The cardiotoxicity of conventional anthracycline therapy highlights a need to search for methods that are highly sensitive and capable of predicting cardiac dysfunction.", "completion": "{\"entities\": [{\"text\": \"cardiotoxicity\", \"type\": \"Disease\"}, {\"text\": \"anthracycline\", \"type\": \"Chemical\"}, {\"text\": \"cardiac dysfunction\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04636", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The patient was extubated 1 week later.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-reassigned-05522", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A clinical trial of hypothermia", "completion": "{\"entities\": [{\"text\": \"hypothermia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02309", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cluster headache is characterized by typical autonomic dysfunctions including facial and intracranial vascular disturbances.", "completion": "{\"entities\": [{\"text\": \"Cluster headache\", \"type\": \"Disease\"}, {\"text\": \"intracranial vascular disturbances\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03948", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Antagonists at serotonin type 6 (5-HT (6 )) receptors show activity in models of learning and memory.", "completion": "{\"entities\": [{\"text\": \"serotonin\", \"type\": \"Chemical\"}, {\"text\": \"5-HT\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02490", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cardona et al .[Nat.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02696", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Ezetimibe undergoes extensive glucuronidation by uridine diphosphate glucoronosyltransferases (UGT) in the intestine and liver and may have inhibited the glucuronidation of simvastatin hydroxy acid, resulting in increased simvastatin exposure and subsequent hepatotoxicity.", "completion": "{\"entities\": [{\"text\": \"Ezetimibe\", \"type\": \"Chemical\"}, {\"text\": \"uridine diphosphate\", \"type\": \"Chemical\"}, {\"text\": \"simvastatin\", \"type\": \"Chemical\"}, {\"text\": \"simvastatin hydroxy acid\", \"type\": \"Chemical\"}, {\"text\": \"hepatotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-03447", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: No ototoxic factor, other than DFO, was present in any of the patients.", "completion": "{\"entities\": [{\"text\": \"ototoxic\", \"type\": \"Disease\"}, {\"text\": \"DFO\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05092", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 01 ). Men who received bupropion had a significant increase in the total IIEF score (54.", "completion": "{\"entities\": [{\"text\": \"bupropion\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02132", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Therefore, TAM - induced hemolysis results from a structural perturbation of red cell membrane, leading to changes in the framework of the erythrocyte membrane and its cytoskeleton caused by its high partition in the membrane.", "completion": "{\"entities\": [{\"text\": \"TAM\", \"type\": \"Chemical\"}, {\"text\": \"hemolysis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03186", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It is referred to as a frontal lobe syndrome.", "completion": "{\"entities\": [{\"text\": \"frontal lobe syndrome\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02182", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, for recipients of organ transplantation, removing the inciting agent is not without the attendant risk of precipitating acute rejection and graft loss.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04088", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: INTRODUCTION: Antibiotic - associated hepatotoxicity is rare.", "completion": "{\"entities\": [{\"text\": \"hepatotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00447", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the current study the efficacy and toxicity of the combination of GEM and VNB in elderly patients with advanced NSCLC or those with some contraindication to receiving cisplatin were assessed.", "completion": "{\"entities\": [{\"text\": \"toxicity\", \"type\": \"Disease\"}, {\"text\": \"GEM\", \"type\": \"Chemical\"}, {\"text\": \"VNB\", \"type\": \"Chemical\"}, {\"text\": \"NSCLC\", \"type\": \"Disease\"}, {\"text\": \"cisplatin\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-02406", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 %(12 of 92 patients) with iodixanol (P = 0.", "completion": "{\"entities\": [{\"text\": \"iodixanol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03299", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A randomized, placebo - controlled dose - comparison trial of haloperidol for psychosis and disruptive behaviors in Alzheimer's disease.", "completion": "{\"entities\": [{\"text\": \"haloperidol\", \"type\": \"Chemical\"}, {\"text\": \"psychosis\", \"type\": \"Disease\"}, {\"text\": \"disruptive behaviors\", \"type\": \"Disease\"}, {\"text\": \"Alzheimer's disease\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02837", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The possibilities that these cardiovascular findings might be the result of non - selective inhibition of monoamine oxidase or of amphetamine and metamphetamine", "completion": "{\"entities\": [{\"text\": \"amphetamine\", \"type\": \"Chemical\"}, {\"text\": \"metamphetamine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01228", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: During culture, no morphological changes were found at effective concentrations of PG-9.", "completion": "{\"entities\": [{\"text\": \"PG-9\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01611", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These effects seem to be equally true for all exposed newborns, regardless of the degree of exposure.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00375", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: No histopathological alterations or differences in bone formation were seen in the limbs or toes of any chicks from any group; however, extensive cranial hemorrhage occurred in all nicotine sulfate - treated chicks.", "completion": "{\"entities\": [{\"text\": \"cranial hemorrhage\", \"type\": \"Disease\"}, {\"text\": \"nicotine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05119", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The historical controls consisted of 50 consecutive patients who underwent CT without prophylactic lamivudine.", "completion": "{\"entities\": [{\"text\": \"lamivudine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04954", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 86% of 1, 821 patients, prolactinomas in 7, 0.", "completion": "{\"entities\": [{\"text\": \"prolactinomas\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00680", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: While contractions to carbachol and ATP were the same in inflamed and in control strips when related to a reference potassium response, isoprenaline - induced relaxations were smaller in inflamed strips.", "completion": "{\"entities\": [{\"text\": \"carbachol\", \"type\": \"Chemical\"}, {\"text\": \"ATP\", \"type\": \"Chemical\"}, {\"text\": \"potassium\", \"type\": \"Chemical\"}, {\"text\": \"isoprenaline\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03897", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: On amphetamine - induced hyperactivity, THP (3.", "completion": "{\"entities\": [{\"text\": \"amphetamine\", \"type\": \"Chemical\"}, {\"text\": \"hyperactivity\", \"type\": \"Disease\"}, {\"text\": \"THP\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04219", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This corresponds, by actuarial (life table) analysis, to a combined gall stone dissolution rate of 58.", "completion": "{\"entities\": [{\"text\": \"gall stone\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03785", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A nonregenerative anemia was the most compromising of the cytopenias and occurred in approximately 50% of dogs receiving 400 - 500 mg / kg cefonicid or 540 - 840 mg / kg cefazedone.", "completion": "{\"entities\": [{\"text\": \"anemia\", \"type\": \"Disease\"}, {\"text\": \"cytopenias\", \"type\": \"Disease\"}, {\"text\": \"cefonicid\", \"type\": \"Chemical\"}, {\"text\": \"cefazedone\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00925", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Antitumor activity was studied using a tumor growth delay assay.", "completion": "{\"entities\": [{\"text\": \"tumor\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00006", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: As naloxone and clonidine do not appear to interact with the same receptor site, the observed functional antagonism suggests the release of an endogenous opiate by clonidine or alpha-methyldopa", "completion": "{\"entities\": [{\"text\": \"naloxone\", \"type\": \"Chemical\"}, {\"text\": \"clonidine\", \"type\": \"Chemical\"}, {\"text\": \"alpha-methyldopa\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00810", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 2 %) had ATT and simultaneous hepatitis virus infection.", "completion": "{\"entities\": [{\"text\": \"hepatitis virus infection\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03543", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Histological evaluation of hearts from all rats given DOX revealed significant slight degrees of perivascular and interstitial fibrosis.", "completion": "{\"entities\": [{\"text\": \"DOX\", \"type\": \"Chemical\"}, {\"text\": \"fibrosis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02628", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05 ). On the Positive and Negative Syndrome Scale positive subscale, all treatments were superior to placebo with LOCF and MMRM; asenapine at 5 mg BID was superior to placebo on the negative subscale with MMRM and on the general psychopathology subscale with LOCF and MMRM.", "completion": "{\"entities\": [{\"text\": \"asenapine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00689", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cognitive ability was assessed by the Mini - Mental State Examination (MMSE ). Patients scoring > or = 20 MMSE sum points were interviewed (n = 79) and questioned regarding symptoms and functional abilities during the week prior to admission.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00247", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After re - infarction, heart size increased in the placebo group and remained unchanged in the timolol", "completion": "{\"entities\": [{\"text\": \"infarction\", \"type\": \"Disease\"}, {\"text\": \"timolol\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02442", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: To the best of our knowledge, this constitutes the first report of HBV lamivudine - resistant strains in therapy - na ve HBV-HIV co-infected patients.", "completion": "{\"entities\": [{\"text\": \"lamivudine\", \"type\": \"Chemical\"}, {\"text\": \"na\", \"type\": \"Chemical\"}, {\"text\": \"HBV-HIV co-infected\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02352", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The otoprotectant L-NAME was administered topically to 12 / 27 animals.", "completion": "{\"entities\": [{\"text\": \"L-NAME\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04782", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Serum hemoglobin, haptoglobin and angiogenesis markers of vascular endothelial growth factor and angiopoetin - 2 were investigated before and after therapy.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02857", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: His renal function remained impaired but stable during 2 years' treatment with captopril but returned to pre - treatment levels soon after cessation of the drug.", "completion": "{\"entities\": [{\"text\": \"captopril\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03415", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05 ), as well as cimetidine trough - concentrations of more than 1.", "completion": "{\"entities\": [{\"text\": \"cimetidine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02931", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: The selected doses of WR242511, which produced significant methemoglobinemia in beagle dogs in earlier studies conducted elsewhere, produced very little MHb (mean < 2.", "completion": "{\"entities\": [{\"text\": \"WR242511\", \"type\": \"Chemical\"}, {\"text\": \"methemoglobinemia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00599", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: v .) injection of U-II causes hypertension and bradycardia and stimulates prolactin and thyrotropin secretion.", "completion": "{\"entities\": [{\"text\": \"U-II\", \"type\": \"Chemical\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}, {\"text\": \"bradycardia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04524", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We examined this theory using the exo utero development system that allows direct and sequential observations of mid - to late - gestation mouse embryos.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03738", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The pharmacological challenge data suggest that tolerance may occur to seizure activity induced by PTZ and PTX 24 h after gamma-HCH, since the response to only these two seizure - inducing agents is decreased.", "completion": "{\"entities\": [{\"text\": \"seizure\", \"type\": \"Disease\"}, {\"text\": \"PTZ\", \"type\": \"Chemical\"}, {\"text\": \"PTX\", \"type\": \"Chemical\"}, {\"text\": \"gamma-HCH\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04003", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In a number of treatment protocols where SRL was combined with a calcineurin inhibitor indications of a synergistic nephrotoxic effect were described.", "completion": "{\"entities\": [{\"text\": \"SRL\", \"type\": \"Chemical\"}, {\"text\": \"nephrotoxic\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04183", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Animal studies and mechanistic studies indicate that nicotine could play a role in accelerating atherosclerosis, but evidence among humans is too inadequate to be definitive about such an effect.", "completion": "{\"entities\": [{\"text\": \"nicotine\", \"type\": \"Chemical\"}, {\"text\": \"atherosclerosis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01183", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A complete responder had relapse - free survival up to 17 months.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00660", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 9 mg / dL at last follow - up (P =. 14 ). Five grafts were lost and the patients returned to dialysis.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01481", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 1 ), or endometrial cancer (RR 0.", "completion": "{\"entities\": [{\"text\": \"endometrial cancer\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04725", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Bradykinin receptors antagonists and nitric oxide synthase inhibitors in vincristine and streptozotocin induced hyperalgesia in chemotherapy and diabetic neuropathy rat model.", "completion": "{\"entities\": [{\"text\": \"Bradykinin\", \"type\": \"Chemical\"}, {\"text\": \"nitric oxide\", \"type\": \"Chemical\"}, {\"text\": \"vincristine\", \"type\": \"Chemical\"}, {\"text\": \"streptozotocin\", \"type\": \"Chemical\"}, {\"text\": \"hyperalgesia\", \"type\": \"Disease\"}, {\"text\": \"diabetic neuropathy\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-00714", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 4 and > 50 inhibition with high concentration of heparin] were included in the study.", "completion": "{\"entities\": [{\"text\": \"heparin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01908", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thirty - four patients with juvenile rheumatoid arthritis, who were treated with flurbiprofen at a maximum dose of 4 mg / kg / day, had statistically significant decreases from baseline in 6 arthritis indices after 12 weeks of treatment.", "completion": "{\"entities\": [{\"text\": \"juvenile rheumatoid arthritis\", \"type\": \"Disease\"}, {\"text\": \"arthritis\", \"type\": \"Disease\"}, {\"text\": \"flurbiprofen\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00716", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Eight of the isolated - HIT patients developed thrombosis within the next 30 d; thus, a total of 48 patients had thrombosis at day 30.", "completion": "{\"entities\": [{\"text\": \"HIT\", \"type\": \"Disease\"}, {\"text\": \"thrombosis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04026", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Investigation of more specific anti - inflammatory agents and hemodiluting agents are warranted in intracerebral hemorrhage", "completion": "{\"entities\": [{\"text\": \"intracerebral hemorrhage\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02792", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: of the patients had significant clinical sings of HBV activation.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04398", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Estradiol is known to influence expression of the long form of prolactin receptors (PRL - R) and components of prolactin' s signaling pathway.", "completion": "{\"entities\": [{\"text\": \"Estradiol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03284", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0001, respectively ). Aortic superoxide production was lower in the Dex + Ato group compared with the group treated with Dex alone (P < 0.", "completion": "{\"entities\": [{\"text\": \"superoxide\", \"type\": \"Chemical\"}, {\"text\": \"Dex\", \"type\": \"Chemical\"}, {\"text\": \"Ato\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01121", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Six epidemiologic studies in the United States and Europe indicate that habitual use of phenacetin is associated with the development of chronic renal failure and end-stage renal disease (ESRD ), with a relative risk in the range of 4 to 19.", "completion": "{\"entities\": [{\"text\": \"phenacetin\", \"type\": \"Chemical\"}, {\"text\": \"chronic renal failure\", \"type\": \"Disease\"}, {\"text\": \"end-stage renal disease\", \"type\": \"Disease\"}, {\"text\": \"ESRD\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03676", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Since adverse reactions are frequent, less than 50 percent of patients are able to continue a particular drug for more than one year.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02056", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Iatrogenically induced intractable atrioventricular reentrant tachycardia after verapamil and catheter ablation in a patient with Wolff-Parkinson-White syndrome and idiopathic dilated cardiomyopathy.", "completion": "{\"entities\": [{\"text\": \"atrioventricular reentrant tachycardia\", \"type\": \"Disease\"}, {\"text\": \"verapamil\", \"type\": \"Chemical\"}, {\"text\": \"Wolff-Parkinson-White syndrome\", \"type\": \"Disease\"}, {\"text\": \"idiopathic dilated cardiomyopathy\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01696", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The ocular myasthenia associated with combination therapy of pegylated IFN alpha-2b and ribavirin for CHC is very rarely reported; therefore, we present this case with a review of the various eye complications of IFN", "completion": "{\"entities\": [{\"text\": \"ocular myasthenia\", \"type\": \"Disease\"}, {\"text\": \"pegylated IFN alpha-2b\", \"type\": \"Chemical\"}, {\"text\": \"IFN\", \"type\": \"Chemical\"}, {\"text\": \"ribavirin\", \"type\": \"Chemical\"}, {\"text\": \"CHC\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-04168", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5% glucose, 2% prilocaine in 7.", "completion": "{\"entities\": [{\"text\": \"glucose\", \"type\": \"Chemical\"}, {\"text\": \"prilocaine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02148", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It has been shown that bromocriptine - induced tachycardia, which persisted after adrenalectomy, is (i) mediated by central dopamine D2 receptor activation and (ii) reduced by 5 - day isoproterenol pretreatment, supporting therefore the hypothesis that this effect is dependent on sympathetic outflow to the heart.", "completion": "{\"entities\": [{\"text\": \"bromocriptine\", \"type\": \"Chemical\"}, {\"text\": \"tachycardia\", \"type\": \"Disease\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}, {\"text\": \"isoproterenol\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04023", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Fucoidan - treated rats exhibited evidence of impaired blood clotting and hemodilution, had larger hematomas, and tended to have less inflammation in the vicinity of the hematoma after three days.", "completion": "{\"entities\": [{\"text\": \"Fucoidan\", \"type\": \"Chemical\"}, {\"text\": \"impaired blood clotting\", \"type\": \"Disease\"}, {\"text\": \"hemodilution\", \"type\": \"Disease\"}, {\"text\": \"hematoma\", \"type\": \"Disease\"}, {\"text\": \"hematomas\", \"type\": \"Disease\"}, {\"text\": \"inflammation\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-00052", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: All reversed to pre - treatment levels after cessation of treatment.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04103", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: DISCUSSION: Telithromycin is the first of the ketolide antibacterials to receive US Food and Drug Administration approval for clinical use.", "completion": "{\"entities\": [{\"text\": \"Telithromycin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01085", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Carbamazepine was switched to its 10 - keto analogue oxcarbazepine among six difficult - to - treat schizophrenic or organic psychotic patients using concomitantly haloperidol, chlorpromazine or clozapine.", "completion": "{\"entities\": [{\"text\": \"Carbamazepine\", \"type\": \"Chemical\"}, {\"text\": \"oxcarbazepine\", \"type\": \"Chemical\"}, {\"text\": \"schizophrenic\", \"type\": \"Disease\"}, {\"text\": \"organic psychotic\", \"type\": \"Disease\"}, {\"text\": \"haloperidol\", \"type\": \"Chemical\"}, {\"text\": \"chlorpromazine\", \"type\": \"Chemical\"}, {\"text\": \"clozapine\", \"type\": \"Chemical\"}]}", "n_entities": 7}
{"ref": "bc5cdr-train-04823", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A high percentage of kanamycin - colistin and povidone-iodine irrigations were associated with erosive cystitis and suggested a possible complication with human usage.", "completion": "{\"entities\": [{\"text\": \"kanamycin\", \"type\": \"Chemical\"}, {\"text\": \"colistin\", \"type\": \"Chemical\"}, {\"text\": \"povidone-iodine\", \"type\": \"Chemical\"}, {\"text\": \"cystitis\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03023", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: A review of admissions during a 6 - year period revealed 14 patients with cocaine - related aneurysms.", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"aneurysms\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00268", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Heredofamilial and connective tissue disorders were rare.", "completion": "{\"entities\": [{\"text\": \"connective tissue disorders\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03620", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: injection of human serum 131I - albumin (131I - HSA ). TEM revealed extensive elastolysis in the arterial wall of D-pen - treated rats, consistent with an inhibitory effect on crosslink formation.", "completion": "{\"entities\": [{\"text\": \"D-pen\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01252", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Development of apomorphine - induced aggressive behavior: comparison of adult male and female Wistar rats.", "completion": "{\"entities\": [{\"text\": \"apomorphine\", \"type\": \"Chemical\"}, {\"text\": \"aggressive behavior\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03563", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Nine patients with severe pain in their feet, which was registered after transplantation, were investigated.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04486", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 9 to 69 ). The absolute risk for bladder cancer in the cohort reached 10% 16 years after diagnosis of Wegener's granulomatosis, and a history of bladder cancer was (non - significantly) twice as common as expected at the time of diagnosis of Wegener's granulomatosis.", "completion": "{\"entities\": [{\"text\": \"bladder cancer\", \"type\": \"Disease\"}, {\"text\": \"Wegener's granulomatosis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-03557", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: An unexpectedly high (11.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02403", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 44 ). In patients with diabetes, SCr increases > or = 0.", "completion": "{\"entities\": [{\"text\": \"diabetes\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01769", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Long - term follow - up of ifosfamide renal toxicity in children treated for malignant mesenchymal tumors: an International Society of Pediatric Oncology report.", "completion": "{\"entities\": [{\"text\": \"ifosfamide\", \"type\": \"Chemical\"}, {\"text\": \"renal toxicity\", \"type\": \"Disease\"}, {\"text\": \"malignant mesenchymal tumors\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03682", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Patterns of hepatic injury induced by methyldopa.", "completion": "{\"entities\": [{\"text\": \"hepatic injury\", \"type\": \"Disease\"}, {\"text\": \"methyldopa\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03695", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We initiated a phase I / II trial to determine the response and toxicity of escalating paclitaxel doses combined with fixed - dose cisplatin with granulocyte colony - stimulating factor support in patients with untreated locally advanced inoperable head and neck carcinoma.", "completion": "{\"entities\": [{\"text\": \"toxicity\", \"type\": \"Disease\"}, {\"text\": \"paclitaxel\", \"type\": \"Chemical\"}, {\"text\": \"cisplatin\", \"type\": \"Chemical\"}, {\"text\": \"head and neck carcinoma\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00614", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pharmacological modulation of pain - related brain activity during normal and central sensitization states in humans.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04932", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A significant difference in MMSE was observed at T30 in patients who received 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00229", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 mg was given by the oral or i.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04531", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, in many cases, the exencephalic brain tissue was preserved with more or less reduction during this period.", "completion": "{\"entities\": [{\"text\": \"exencephalic\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01014", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These changes might offer protection to brain tissue during periods of induced hypotension", "completion": "{\"entities\": [{\"text\": \"hypotension\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03971", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Comparison of developmental toxicity of selective and non - selective cyclooxygenase - 2 inhibitors in CRL :(WI) WUBR Wistar rats -- DFU and piroxicam study.", "completion": "{\"entities\": [{\"text\": \"toxicity\", \"type\": \"Disease\"}, {\"text\": \"DFU\", \"type\": \"Chemical\"}, {\"text\": \"piroxicam\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02192", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: He was hospitalized for a myocardial infarction with pulmonary edema, treated with high - dose diuretics.", "completion": "{\"entities\": [{\"text\": \"myocardial infarction\", \"type\": \"Disease\"}, {\"text\": \"pulmonary edema\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00427", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Adverse effects of the atypical antipsychotics.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03548", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05 ). cTnT found in rats after 12 mg / kg were significantly greater than that found after 7.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02507", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Symptoms persisted for three months despite TAC dose reduction, administration of IVIG and four doses of methylprednisolone pulse therapy.", "completion": "{\"entities\": [{\"text\": \"TAC\", \"type\": \"Chemical\"}, {\"text\": \"methylprednisolone\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05167", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Acute psychosis due to treatment with phenytoin in a nonepileptic patient.", "completion": "{\"entities\": [{\"text\": \"Acute psychosis\", \"type\": \"Disease\"}, {\"text\": \"phenytoin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01571", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Sirolimus represents a major therapeutic advance in the prevention of acute renal allograft rejection and chronic allograft nephropathy.", "completion": "{\"entities\": [{\"text\": \"Sirolimus\", \"type\": \"Chemical\"}, {\"text\": \"nephropathy\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04208", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Octreotide, an effective treatment for acromegaly, induces gall bladder stones in 13 - 60% of patients.", "completion": "{\"entities\": [{\"text\": \"Octreotide\", \"type\": \"Chemical\"}, {\"text\": \"acromegaly\", \"type\": \"Disease\"}, {\"text\": \"gall bladder stones\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01852", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The possible beneficial effect of ribavirin during the initial days of AHF", "completion": "{\"entities\": [{\"text\": \"ribavirin\", \"type\": \"Chemical\"}, {\"text\": \"AHF\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04745", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: No association was found with other pretreatment characteristics.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02201", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Grape seed extract, primarily a mixture of proanthocyanidins, has been shown to modulate a wide - range of biological, pharmacological and toxicological effects which are mainly cytoprotective.", "completion": "{\"entities\": [{\"text\": \"Grape seed extract\", \"type\": \"Chemical\"}, {\"text\": \"proanthocyanidins\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01187", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Administration of this regimen to breast cancer patients who have been treated by chemotherapy and those with impaired heart function", "completion": "{\"entities\": [{\"text\": \"breast cancer\", \"type\": \"Disease\"}, {\"text\": \"impaired heart function\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04416", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: E2 decreased the accumulation of cholesteryl esters in macrophages following ritonavir treatment.", "completion": "{\"entities\": [{\"text\": \"E2\", \"type\": \"Chemical\"}, {\"text\": \"cholesteryl esters\", \"type\": \"Chemical\"}, {\"text\": \"ritonavir\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02179", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cyclosporine and tacrolimus - associated thrombotic microangiopathy.", "completion": "{\"entities\": [{\"text\": \"Cyclosporine\", \"type\": \"Chemical\"}, {\"text\": \"tacrolimus\", \"type\": \"Chemical\"}, {\"text\": \"thrombotic microangiopathy\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-05007", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thus the mechanism by which acetaminophen antagonizes the actions of caffeine", "completion": "{\"entities\": [{\"text\": \"acetaminophen\", \"type\": \"Chemical\"}, {\"text\": \"caffeine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03767", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Alpha-lipoic acid protects sensory neurons through its anti - oxidant and mitochondrial regulatory functions, possibly inducing the expression of frataxin.", "completion": "{\"entities\": [{\"text\": \"Alpha-lipoic acid\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02511", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Valvular heart abnormalities have been reported in patients with Parkinson's disease (PD) treated with pergolide.", "completion": "{\"entities\": [{\"text\": \"Valvular heart abnormalities\", \"type\": \"Disease\"}, {\"text\": \"Parkinson's disease\", \"type\": \"Disease\"}, {\"text\": \"PD\", \"type\": \"Disease\"}, {\"text\": \"pergolide\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02887", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The patient recovered spontaneously in 3 hours under surveillance in the hospital.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01428", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 mg / kg BW) or their combinations with cholinolytic drug atropine sulfate (50.", "completion": "{\"entities\": [{\"text\": \"atropine sulfate\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04314", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Depletion of dopamine in the striatum was also antagonized when LY274614 was given after the injection of amphetamine; LY274614 protected when given up to 4 hr after but not when given 8 or 24 hr after amphetamine.", "completion": "{\"entities\": [{\"text\": \"dopamine\", \"type\": \"Chemical\"}, {\"text\": \"LY274614\", \"type\": \"Chemical\"}, {\"text\": \"amphetamine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03484", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Also the enhancement of verapamil", "completion": "{\"entities\": [{\"text\": \"verapamil\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04576", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Readministration of amantadine, after a drug - free overnight period, increased motility from respective saline control in all strains with exception of the BALB / C mice where suppression of motility occurred.", "completion": "{\"entities\": [{\"text\": \"amantadine\", \"type\": \"Chemical\"}, {\"text\": \"suppression of motility\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00784", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSION: This work shows that confusion with valproic acid", "completion": "{\"entities\": [{\"text\": \"confusion\", \"type\": \"Disease\"}, {\"text\": \"valproic acid\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01851", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: From these results, we conclude that ribavirin has an antiviral effect in advanced cases of AHF, and that anemia, the only secondary reaction observed, can be easily managed.", "completion": "{\"entities\": [{\"text\": \"ribavirin\", \"type\": \"Chemical\"}, {\"text\": \"AHF\", \"type\": \"Disease\"}, {\"text\": \"anemia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01281", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: PTCR also occurs in certain native kidney diseases, though the association is not as strong as that for TG.", "completion": "{\"entities\": [{\"text\": \"kidney diseases\", \"type\": \"Disease\"}, {\"text\": \"TG\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04112", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cases were patients who developed hyperkalemia (K (+)> 5.", "completion": "{\"entities\": [{\"text\": \"hyperkalemia\", \"type\": \"Disease\"}, {\"text\": \"K\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00844", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: TAKE HOME MESSAGE: Capecitabine is an oral prodrug of 5-FU and was developed to fulfill the need for a more convenient therapy and provide an improved safety / efficacy profile.", "completion": "{\"entities\": [{\"text\": \"Capecitabine\", \"type\": \"Chemical\"}, {\"text\": \"5-FU\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02022", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: During treatment with octreotide, 17 patients developed sludge, 10 had gallstones, and 1 developed acute cholecystitis requiring surgery.", "completion": "{\"entities\": [{\"text\": \"octreotide\", \"type\": \"Chemical\"}, {\"text\": \"gallstones\", \"type\": \"Disease\"}, {\"text\": \"acute cholecystitis\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01026", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The first twin, a female, had a left Potter-type IIa polycystic kidney and a rudimentary left uterine cornu.", "completion": "{\"entities\": [{\"text\": \"Potter-type IIa polycystic kidney\", \"type\": \"Disease\"}, {\"text\": \"rudimentary left uterine cornu\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02321", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Similar to rats, systemic pilocarpine injection causes status epilepticus (SE) and the eventual development of spontaneous seizures and mossy fiber sprouting in C57BL / 6 and CD1 mice, but the physiological correlates of these events have not been identified in mice.", "completion": "{\"entities\": [{\"text\": \"pilocarpine\", \"type\": \"Chemical\"}, {\"text\": \"status epilepticus\", \"type\": \"Disease\"}, {\"text\": \"SE\", \"type\": \"Disease\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04549", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: DBA / 2J, BALB / cByJ and NZW / LacJ strains exhibited intermediate sensitivity.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02145", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Inhibition of NO - synthase induced a reversible hypertension accompanied by depressed Na +- extrusion from cardiac cells as a consequence of deteriorated Na +- binding properties of the (Na, K )- ATPase.", "completion": "{\"entities\": [{\"text\": \"NO\", \"type\": \"Chemical\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}, {\"text\": \"depressed\", \"type\": \"Disease\"}, {\"text\": \"Na\", \"type\": \"Chemical\"}, {\"text\": \"K\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-03303", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 75 mg / day (low dose ), were compared in 71 outpatients with Alzheimer's disease.", "completion": "{\"entities\": [{\"text\": \"Alzheimer's disease\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02766", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: There recently has been a resurgence in the utilization of ketamine, a unique anesthetic, for emergency - department procedures requiring sedation.", "completion": "{\"entities\": [{\"text\": \"ketamine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01075", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Vitamin B12 and folinic acid supplementation of ZDV therapy does not seem useful in preventing or reducing ZDV - induced myelotoxicity", "completion": "{\"entities\": [{\"text\": \"Vitamin B12\", \"type\": \"Chemical\"}, {\"text\": \"folinic acid\", \"type\": \"Chemical\"}, {\"text\": \"ZDV\", \"type\": \"Chemical\"}, {\"text\": \"myelotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-reassigned-04529", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Long term hormone therapy for perimenopausal and postmenopausal women.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00990", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: They are thus more important during absolute hypovolemia than during deliberate hypotension", "completion": "{\"entities\": [{\"text\": \"hypovolemia\", \"type\": \"Disease\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01642", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: Cocaine is a widely abused psychostimulant that has both rewarding and aversive properties.", "completion": "{\"entities\": [{\"text\": \"Cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05218", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These studies were conducted to examine the differential response to a drug challenge under varied experimental test conditions routinely employed to study drug - induced behavioral and neurophysiological responses in rodents.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00897", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Its occurrence in a patient being treated with imipramine is described, representing the first reported case of this syndrome in conjunction with antidepressants.", "completion": "{\"entities\": [{\"text\": \"imipramine\", \"type\": \"Chemical\"}, {\"text\": \"antidepressants\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00496", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Sedation has been commonly used in the neonate to decrease the stress and pain from the noxious stimuli and invasive procedures in the neonatal intensive care unit, as well as to facilitate synchrony between ventilator and spontaneous breaths.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01432", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The rats treated with DFP - atropine showed severe typical OP - induced toxicity signs.", "completion": "{\"entities\": [{\"text\": \"DFP\", \"type\": \"Chemical\"}, {\"text\": \"atropine\", \"type\": \"Chemical\"}, {\"text\": \"OP\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00164", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Her red blood cells (RBCs) had increased incubated Heinz body formation, decreased reduced glutathione (GSH ), and decreased GSH stability.", "completion": "{\"entities\": [{\"text\": \"glutathione\", \"type\": \"Chemical\"}, {\"text\": \"GSH\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03691", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In this latter patient, and in 2 others, the causal relationship between methyldopa and hepatic dysfunction was proved with the recurrence of hepatitis", "completion": "{\"entities\": [{\"text\": \"methyldopa\", \"type\": \"Chemical\"}, {\"text\": \"hepatic dysfunction\", \"type\": \"Disease\"}, {\"text\": \"hepatitis\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04188", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Seizure resulting from a venlafaxine overdose.", "completion": "{\"entities\": [{\"text\": \"Seizure\", \"type\": \"Disease\"}, {\"text\": \"venlafaxine\", \"type\": \"Chemical\"}, {\"text\": \"overdose\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02186", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, literature regarding the incidence of the recurrence of TMA in patients exposed sequentially to cyclosporine and tacrolimus is limited.", "completion": "{\"entities\": [{\"text\": \"TMA\", \"type\": \"Disease\"}, {\"text\": \"cyclosporine\", \"type\": \"Chemical\"}, {\"text\": \"tacrolimus\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02686", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Simvastatin-ezetimibe - induced hepatic failure necessitating liver transplantation.", "completion": "{\"entities\": [{\"text\": \"Simvastatin-ezetimibe\", \"type\": \"Chemical\"}, {\"text\": \"hepatic failure\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00078", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After her strength returned, repetitive stimulation was normal, but single fiber EMG revealed increased jitter and blocking.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02092", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It has not been reported previously in children.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03466", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We tested the hypothesis that the antagonistic effect of IL - 3 and EPO on erythroid cells may be mediated by endothelial cells.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00286", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The co - administration of aspirin with N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide (FANFT) to rats resulted in a reduced incidence of FANFT - induced bladder carcinomas but a concomitant induction of forestomach tumors.", "completion": "{\"entities\": [{\"text\": \"aspirin\", \"type\": \"Chemical\"}, {\"text\": \"N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide\", \"type\": \"Chemical\"}, {\"text\": \"FANFT\", \"type\": \"Chemical\"}, {\"text\": \"bladder carcinomas\", \"type\": \"Disease\"}, {\"text\": \"forestomach tumors\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-04200", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Nifedipine significantly improved kidney function as indicated by a significant lowering of serum creatinine levels at 6 and 12 months.", "completion": "{\"entities\": [{\"text\": \"Nifedipine\", \"type\": \"Chemical\"}, {\"text\": \"creatinine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00816", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Most had hyperacute presentation; the median icterus encephalopathy interval was 4.", "completion": "{\"entities\": [{\"text\": \"icterus\", \"type\": \"Disease\"}, {\"text\": \"encephalopathy\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04235", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Adriamycin (50 mg / 50 ml) was administered intravesically within 24 h after transurethral resection of TA - T1 (O - A) bladder tumors.", "completion": "{\"entities\": [{\"text\": \"Adriamycin\", \"type\": \"Chemical\"}, {\"text\": \"bladder tumors\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05044", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Fifty - two patients suffering from intractable tinnitus entered this therapeutic trial, but only nine finished all five courses.", "completion": "{\"entities\": [{\"text\": \"tinnitus\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05181", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: During monitoring, visual hallucinations did not correlate with EEG readings, nor did video recording capture any of the described events.", "completion": "{\"entities\": [{\"text\": \"visual hallucinations\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02984", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: DESIGN: Retrospective analysis of a randomized phase II trial.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01389", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Combined androgen blockade - induced anemia in prostate cancer patients without bone involvement.", "completion": "{\"entities\": [{\"text\": \"anemia\", \"type\": \"Disease\"}, {\"text\": \"prostate cancer\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00523", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 (95 percent confidence interval, 1.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03370", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSION: This study demonstrates that cinacalcet is a strong inhibitor of CYP2D6.", "completion": "{\"entities\": [{\"text\": \"cinacalcet\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01415", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It is important to recognize the rare and potentially reversible toxicity of AmB", "completion": "{\"entities\": [{\"text\": \"toxicity\", \"type\": \"Disease\"}, {\"text\": \"AmB\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02144", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The K (Na) value for Na + returned to control value.", "completion": "{\"entities\": [{\"text\": \"K\", \"type\": \"Chemical\"}, {\"text\": \"Na\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00273", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The overall incidence of side effects and the frequency and severity of blurred vision, dry mouth, and drowsiness were significantly less with dothiepin than with amitriptyline.", "completion": "{\"entities\": [{\"text\": \"blurred vision\", \"type\": \"Disease\"}, {\"text\": \"dry mouth\", \"type\": \"Disease\"}, {\"text\": \"dothiepin\", \"type\": \"Chemical\"}, {\"text\": \"amitriptyline\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04073", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Assay for mitochondrial respiratory function and histopathological examination of heart tissues were performed.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04660", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The co - primary endpoint of being pain free at 2 h was also in favor of rizatriptan.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"rizatriptan\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01334", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 3 %). The difference in the percentage of patients with a 50% reduction in their nausea was 12.", "completion": "{\"entities\": [{\"text\": \"nausea\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02420", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 01 ). CONCLUSIONS: The rate of contrast - induced nephropathy, defined by multiple end points, is not statistically different after the intraarterial administration of iopamidol or iodixanol to high - risk patients, with or without diabetes mellitus", "completion": "{\"entities\": [{\"text\": \"nephropathy\", \"type\": \"Disease\"}, {\"text\": \"iopamidol\", \"type\": \"Chemical\"}, {\"text\": \"iodixanol\", \"type\": \"Chemical\"}, {\"text\": \"diabetes mellitus\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01945", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Intra - arterial BCNU chemotherapy for treatment of malignant gliomas of the central nervous system.", "completion": "{\"entities\": [{\"text\": \"BCNU\", \"type\": \"Chemical\"}, {\"text\": \"malignant gliomas\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04867", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Safety assessments were made at baseline and at 2, 4, 6, and 12 weeks after the start of product use.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00926", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Acute normal tissue toxicities (i.", "completion": "{\"entities\": [{\"text\": \"toxicities\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01471", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Risk in the raloxifene group was higher than in the placebo group for the first 2 years, but decreased to about the same rate as in the placebo group thereafter.", "completion": "{\"entities\": [{\"text\": \"raloxifene\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05161", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Haloperidol administration (one dose of 12 mg / kg once a week s.", "completion": "{\"entities\": [{\"text\": \"Haloperidol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03139", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: PURPOSE: To evaluate the response rate and toxic effects of vinorelbine (VNB) administered as a single agent in metastatic squamous cell esophageal carcinoma.", "completion": "{\"entities\": [{\"text\": \"vinorelbine\", \"type\": \"Chemical\"}, {\"text\": \"VNB\", \"type\": \"Chemical\"}, {\"text\": \"squamous cell esophageal carcinoma\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01715", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 1 mg iv) and 12 patients received ephedrine (10 mg iv) to restore mean arterial pressure (MAP ). Heart rate (HR ), MAP, stroke volume (SV ), cardiac output (CO ), and frontal lobe oxygenation (S (c) O (2 )) were registered.", "completion": "{\"entities\": [{\"text\": \"ephedrine\", \"type\": \"Chemical\"}, {\"text\": \"stroke\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02921", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Anaesthetists' nightmare: masseter spasm after induction in an undiagnosed case of myotonia congenita.", "completion": "{\"entities\": [{\"text\": \"masseter spasm\", \"type\": \"Disease\"}, {\"text\": \"myotonia congenita\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00741", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSION (S ): This is the first reported case of central retinal vein occlusion after treatment with CC.", "completion": "{\"entities\": [{\"text\": \"retinal vein occlusion\", \"type\": \"Disease\"}, {\"text\": \"CC\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03414", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These 6 patients had both renal and liver dysfunction (P less than 0.", "completion": "{\"entities\": [{\"text\": \"renal and liver dysfunction\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01118", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Atracurium besylate, a short - acting benzylisoquinolinium NMBA that is eliminated independently of renal or hepatic function, has also been associated with persistent paralysis, but only when used with corticosteroids.", "completion": "{\"entities\": [{\"text\": \"Atracurium besylate\", \"type\": \"Chemical\"}, {\"text\": \"benzylisoquinolinium\", \"type\": \"Chemical\"}, {\"text\": \"paralysis\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-reassigned-03523", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 53) or ST depression (p = 0.", "completion": "{\"entities\": [{\"text\": \"depression\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04217", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Of the 12 patients considered for oral ursodeoxycholic acid (UDCA) treatment, two had a blocked cystic duct and were not started on UDCA while one was lost to follow up.", "completion": "{\"entities\": [{\"text\": \"ursodeoxycholic acid\", \"type\": \"Chemical\"}, {\"text\": \"UDCA\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01927", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Maternal lithium and neonatal Ebstein's anomaly: evaluation with cross - sectional echocardiography.", "completion": "{\"entities\": [{\"text\": \"lithium\", \"type\": \"Chemical\"}, {\"text\": \"Ebstein's anomaly\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04251", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In all of them normal serum potassium levels reached within 2 to 4 days of stopping sulindac.", "completion": "{\"entities\": [{\"text\": \"potassium\", \"type\": \"Chemical\"}, {\"text\": \"sulindac\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-02670", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 mg doxorubicin / kg.", "completion": "{\"entities\": [{\"text\": \"doxorubicin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00501", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Highly active antiretroviral therapy (HAART) is implicated in cardiomyopathy (CM) and in elevated plasma lactate (LA) in AIDS through mechanisms of mitochondrial dysfunction.", "completion": "{\"entities\": [{\"text\": \"cardiomyopathy\", \"type\": \"Disease\"}, {\"text\": \"CM\", \"type\": \"Disease\"}, {\"text\": \"lactate\", \"type\": \"Chemical\"}, {\"text\": \"LA\", \"type\": \"Chemical\"}, {\"text\": \"AIDS\", \"type\": \"Disease\"}, {\"text\": \"mitochondrial dysfunction\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-03699", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Treatment, given every 21 days for a maximum of three cycles, consisted of paclitaxel by 3 - hour infusion followed the next day by a fixed dose of cisplatin (75 mg / m2 ). The dose levels incorporate escalating paclitaxel doses, and intrapatient escalations within a given dose level are permitted if toxicity permits.", "completion": "{\"entities\": [{\"text\": \"paclitaxel\", \"type\": \"Chemical\"}, {\"text\": \"cisplatin\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00049", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Five of 8 patients (63 %) improved during fusidic acid treatment: 3 at two weeks and 2 after four weeks.", "completion": "{\"entities\": [{\"text\": \"fusidic acid\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03268", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Atorvastatin (Ato) possesses pleiotropic properties that have been reported to improve endothelial function through increased availability of NO and reduced O2- production in various forms of hypertension.", "completion": "{\"entities\": [{\"text\": \"Ato\", \"type\": \"Chemical\"}, {\"text\": \"Atorvastatin\", \"type\": \"Chemical\"}, {\"text\": \"NO\", \"type\": \"Chemical\"}, {\"text\": \"O2-\", \"type\": \"Chemical\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-01653", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 6 mg / day for clonidine and 60 mg / day for methylphenidate (both with divided dosing ). Groups were compared regarding adverse events and changes from baseline to week 16 in electrocardiograms and vital signs.", "completion": "{\"entities\": [{\"text\": \"clonidine\", \"type\": \"Chemical\"}, {\"text\": \"methylphenidate\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05017", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In contrast with other beta blockers, flestolol - induced effects reverse rapidly (within 30 minutes) following discontinuation because of its short half - life.", "completion": "{\"entities\": [{\"text\": \"flestolol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00108", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Injection of Captopril (1 mg / kg ), an inhibitor of angiotensin converting enzyme (ACE ), reduced both pulmonary and renal insufficiency in this rat model.", "completion": "{\"entities\": [{\"text\": \"Captopril\", \"type\": \"Chemical\"}, {\"text\": \"angiotensin\", \"type\": \"Chemical\"}, {\"text\": \"pulmonary and renal insufficiency\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02947", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Following recovery, the monkeys were selectively deafened for high frequencies using kanamycin and furosemide.", "completion": "{\"entities\": [{\"text\": \"kanamycin\", \"type\": \"Chemical\"}, {\"text\": \"furosemide\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02481", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 125 ). Thus, proteinuria may develop in cardiac transplant patients after switch to Srl, which may have an adverse effect on renal function in these patients.", "completion": "{\"entities\": [{\"text\": \"proteinuria\", \"type\": \"Disease\"}, {\"text\": \"Srl\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04399", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: To test the hypothesis that estrogen increases PRL - R expression and sensitivity to prolactin, we next demonstrated that estradiol greatly augments prolactin - induced STAT5 activation.", "completion": "{\"entities\": [{\"text\": \"estrogen\", \"type\": \"Chemical\"}, {\"text\": \"estradiol\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02116", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Patients with CIMD had symptom severity levels between those of patients with and without a mood disorder.", "completion": "{\"entities\": [{\"text\": \"CIMD\", \"type\": \"Disease\"}, {\"text\": \"mood disorder\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04083", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pretreatment with either VPU (50 and 100 mg / kg) or VPA (300 and 600 mg / kg) completely abolished pilocarpine - evoked increases in extracellular glutamate and aspartate.", "completion": "{\"entities\": [{\"text\": \"VPU\", \"type\": \"Chemical\"}, {\"text\": \"VPA\", \"type\": \"Chemical\"}, {\"text\": \"pilocarpine\", \"type\": \"Chemical\"}, {\"text\": \"glutamate\", \"type\": \"Chemical\"}, {\"text\": \"aspartate\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-00413", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The possibility of a clinically relevant dopamine - antagonistic capacity of fluoxetine in Parkinson's disease", "completion": "{\"entities\": [{\"text\": \"dopamine\", \"type\": \"Chemical\"}, {\"text\": \"fluoxetine\", \"type\": \"Chemical\"}, {\"text\": \"Parkinson's disease\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04665", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 9% for rizatriptan and 47.", "completion": "{\"entities\": [{\"text\": \"rizatriptan\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04842", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Vehicle / drugs were administered daily for 21days to male Wistar rats.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03713", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A total of 167 courses at doses of 15 to 70 mg / m2 were evaluable.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00020", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Fasciculations in six areas of the body were scored from 0 to 3 and summated as a total fasciculation score.", "completion": "{\"entities\": [{\"text\": \"Fasciculations\", \"type\": \"Disease\"}, {\"text\": \"fasciculation\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03931", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: The combination of cisplatin and amifostine in this study resulted in an overall response rate of 16 %. Neither a tumor - protective effect nor reduced toxicity to normal tissues was observed with the addition of amifostine to cisplatin", "completion": "{\"entities\": [{\"text\": \"cisplatin\", \"type\": \"Chemical\"}, {\"text\": \"amifostine\", \"type\": \"Chemical\"}, {\"text\": \"tumor\", \"type\": \"Disease\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01601", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Does smoking during pregnancy affect the amplitudes of transient evoked otoacoustic emissions in newborns ? OBJECTIVE: Maternal tobacco smoking has negative effects on fetal growth.", "completion": "{\"entities\": [{\"text\": \"smoking\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03063", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Administration of [3H]-5-azadeoxycytidine during the repair synthesis induced by 1,2-DMH further showed that 0.", "completion": "{\"entities\": [{\"text\": \"[3H]-5-azadeoxycytidine\", \"type\": \"Chemical\"}, {\"text\": \"1,2-DMH\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03810", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: NRA0160 and clozapine significantly reversed the disruption of prepulse inhibition (PPI) in rats produced by apomorphine.", "completion": "{\"entities\": [{\"text\": \"NRA0160\", \"type\": \"Chemical\"}, {\"text\": \"clozapine\", \"type\": \"Chemical\"}, {\"text\": \"apomorphine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03482", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The [verapamil] o that arrested atrial beating (AC) was also potentiated with the order LNa = LNa + LCa = LNa + HCa = LCa > HCa = N.", "completion": "{\"entities\": [{\"text\": \"verapamil\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01886", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The incidence of cardiotoxicity was not higher in patients with signs of cardiovascular disease than in those without in the pre - treatment evaluation.", "completion": "{\"entities\": [{\"text\": \"cardiotoxicity\", \"type\": \"Disease\"}, {\"text\": \"cardiovascular disease\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00211", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The abruptness of the renal failure and its reversibility within days suggests that there was a functional component to the renal dysfunction.", "completion": "{\"entities\": [{\"text\": \"renal failure\", \"type\": \"Disease\"}, {\"text\": \"renal dysfunction\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04211", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the remaining 12 patients, localised computed tomography of the gall bladder showed that eight had stones with maximum attenuation scores of < 100 Hounsfield units (values of < 100 HU predict cholesterol rich, dissolvable stones ). Gall bladder bile was obtained by ultrasound guided, fine needle puncture from six patients.", "completion": "{\"entities\": [{\"text\": \"cholesterol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05085", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: After 12 weeks of treatment, the mean (sd) scores for CGI - SF were significantly lower, i.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04619", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: When respiratory failure was produced by hypoventilation (pH 7.", "completion": "{\"entities\": [{\"text\": \"respiratory failure\", \"type\": \"Disease\"}, {\"text\": \"hypoventilation\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05057", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The morphine - induced hyperactivity was potentiated by scopolamine and attenuated by physostigmine.", "completion": "{\"entities\": [{\"text\": \"morphine\", \"type\": \"Chemical\"}, {\"text\": \"hyperactivity\", \"type\": \"Disease\"}, {\"text\": \"scopolamine\", \"type\": \"Chemical\"}, {\"text\": \"physostigmine\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03318", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 mg / kg intravenously (i.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03709", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A phase I study of 4'-0-tetrahydropyranyladriamycin.", "completion": "{\"entities\": [{\"text\": \"4'-0-tetrahydropyranyladriamycin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02455", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Enhancement of morphine antinociception by dextromethorphan was seen in both males and females in the acute pain models, with the magnitude of this effect being greater in males.", "completion": "{\"entities\": [{\"text\": \"morphine\", \"type\": \"Chemical\"}, {\"text\": \"dextromethorphan\", \"type\": \"Chemical\"}, {\"text\": \"acute pain\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02216", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Palpebral twitching in a depressed adolescent on citalopram.", "completion": "{\"entities\": [{\"text\": \"Palpebral twitching\", \"type\": \"Disease\"}, {\"text\": \"depressed\", \"type\": \"Disease\"}, {\"text\": \"citalopram\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02248", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cranial magnetic resonance imaging and extensive laboratory studies failed to reveal structural lesions of the brain and metabolic abnormalities.", "completion": "{\"entities\": [{\"text\": \"structural lesions of the brain\", \"type\": \"Disease\"}, {\"text\": \"metabolic abnormalities\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00623", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: MDMA polydrug users show process - specific central executive impairments coupled with impaired social and emotional judgement processes.", "completion": "{\"entities\": [{\"text\": \"MDMA\", \"type\": \"Chemical\"}, {\"text\": \"impaired social and emotional judgement processes\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03089", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We report a patient in whom hypersensitivity to carbamazepine presented with generalized erythroderma, a severe leukemoid reaction, eosinophilia, hyponatremia, and renal failure.", "completion": "{\"entities\": [{\"text\": \"hypersensitivity\", \"type\": \"Disease\"}, {\"text\": \"carbamazepine\", \"type\": \"Chemical\"}, {\"text\": \"erythroderma\", \"type\": \"Disease\"}, {\"text\": \"leukemoid reaction\", \"type\": \"Disease\"}, {\"text\": \"eosinophilia\", \"type\": \"Disease\"}, {\"text\": \"hyponatremia\", \"type\": \"Disease\"}, {\"text\": \"renal failure\", \"type\": \"Disease\"}]}", "n_entities": 7}
{"ref": "bc5cdr-train-01530", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Furthermore, DCE reversed the amnesia induced by scopolamine (0.", "completion": "{\"entities\": [{\"text\": \"DCE\", \"type\": \"Chemical\"}, {\"text\": \"amnesia\", \"type\": \"Disease\"}, {\"text\": \"scopolamine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03722", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 minutes, and T 1 / 2 gamma of 23.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01551", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: She was unable to urinate.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01606", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Exposure to tobacco was characterized as low (< 5 cigarettes per day, n = 88 ears ), moderate (5 < or = cigarettes per day < 10, n = 76) or high (> or = 10 cigarettes per day, n = 36 ). RESULTS: In exposed neonates, TEOAEs mean response (across frequency) and mean amplitude at 4000Hz was significantly lower than in non - exposed neonates.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01814", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The study was designed to have a power of greater than 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02093", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Stevens-Johnson syndrome is a well - recognized immune complex - mediated hypersensitivity reaction that affects all age groups, is drug or infection induced, and has classic systemic, mucosal, and dermatologic manifestations.", "completion": "{\"entities\": [{\"text\": \"Stevens-Johnson syndrome\", \"type\": \"Disease\"}, {\"text\": \"hypersensitivity\", \"type\": \"Disease\"}, {\"text\": \"infection\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-05176", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Further work is warranted on the effect of the treatments on renal functional aspects in models of chronic renal failure", "completion": "{\"entities\": [{\"text\": \"chronic renal failure\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04836", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Curcumin ameliorates cognitive dysfunction and oxidative damage in phenobarbitone and carbamazepine administered rats.", "completion": "{\"entities\": [{\"text\": \"Curcumin\", \"type\": \"Chemical\"}, {\"text\": \"cognitive dysfunction\", \"type\": \"Disease\"}, {\"text\": \"phenobarbitone\", \"type\": \"Chemical\"}, {\"text\": \"carbamazepine\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02376", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: PURPOSE: To assess the incidence of postoperative emetic side effects after the administration of methylprednisolone and gentamicin into the posterior sub - Tenon' s space at the end of routine cataract surgery.", "completion": "{\"entities\": [{\"text\": \"methylprednisolone\", \"type\": \"Chemical\"}, {\"text\": \"gentamicin\", \"type\": \"Chemical\"}, {\"text\": \"cataract\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04958", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We now advocate that before age 50 years testosterone be determined only in cases of low sexual desire and abnormal physical examination but that it be measured in all men older than 50 years.", "completion": "{\"entities\": [{\"text\": \"testosterone\", \"type\": \"Chemical\"}, {\"text\": \"low sexual desire\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03519", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Conventional spin echo images were acquired in the sagittal and transverse orientation.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04904", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: OBJECTIVE: To describe a case of propylthiouracil - induced vasculitis manifesting with pericarditis.", "completion": "{\"entities\": [{\"text\": \"propylthiouracil\", \"type\": \"Chemical\"}, {\"text\": \"vasculitis\", \"type\": \"Disease\"}, {\"text\": \"pericarditis\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01011", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 16 ml / 100 g min - 1 ), while CBF was unchanged.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03279", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In rats treated with Dex alone, SBP was increased from 109 +/- 2 to 133 +/- 2 mmHg on Days 4 and Day 14, respectively (P < 0.", "completion": "{\"entities\": [{\"text\": \"Dex\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04900", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In contrast, monkeys with long - term MPTP exposure, slow symptom progression and / or long symptom duration prior to initiation of levodopa therapy were more resistant to developing LIDs (e.", "completion": "{\"entities\": [{\"text\": \"MPTP\", \"type\": \"Chemical\"}, {\"text\": \"levodopa\", \"type\": \"Chemical\"}, {\"text\": \"LIDs\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01933", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The effects of exercise on the severity of isoproterenol - induced myocardial infarction were studied in female albino rats of 20, 40, 60 and 80 weeks of age.", "completion": "{\"entities\": [{\"text\": \"isoproterenol\", \"type\": \"Chemical\"}, {\"text\": \"myocardial infarction\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02988", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This 4 - week cycle was repeated until there was evidence of excessive toxicity or disease progression.", "completion": "{\"entities\": [{\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03764", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Our results demonstrate that both cisplatin and paclitaxel cause early mitochondrial impairment with loss of membrane potential and induction of autophagic vacuoles in neurons.", "completion": "{\"entities\": [{\"text\": \"cisplatin\", \"type\": \"Chemical\"}, {\"text\": \"paclitaxel\", \"type\": \"Chemical\"}, {\"text\": \"mitochondrial impairment\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03434", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In contrast, 7H6 and ZO - 1 immunostaining was more discontinuous, outlining the bile canaliculi after BDL.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00449", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: All patients were evaluable for response and toxicity.", "completion": "{\"entities\": [{\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00655", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These patients showed persistently good graft function.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03006", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This case report shows that ciprofloxacin may precipitate life - threatening thrombocytopenia and haemolytic anaemia", "completion": "{\"entities\": [{\"text\": \"ciprofloxacin\", \"type\": \"Chemical\"}, {\"text\": \"thrombocytopenia\", \"type\": \"Disease\"}, {\"text\": \"haemolytic anaemia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02917", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Lindane is also widely used as an agricultural and industrial pesticide, and as a result the toxic profile of this insecticide is well understood.", "completion": "{\"entities\": [{\"text\": \"Lindane\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00115", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In a randomized study, labetalol - induced hypotension and nitroprusside - induced hypotension were compared in 20 patients (10 in each group) scheduled for major orthopedic procedures.", "completion": "{\"entities\": [{\"text\": \"labetalol\", \"type\": \"Chemical\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}, {\"text\": \"nitroprusside\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00384", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: An initial dose of 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01437", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We have recently shown that estrogen negatively modulates the hypotensive effect of clonidine (mixed alpha2 -/ I1 - receptor agonist) in female rats and implicates the cardiovascular autonomic control in this interaction.", "completion": "{\"entities\": [{\"text\": \"estrogen\", \"type\": \"Chemical\"}, {\"text\": \"hypotensive\", \"type\": \"Disease\"}, {\"text\": \"clonidine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04137", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 6% in the control group.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00482", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: Concerns about possible risks of switching to mania associated with antidepressants continue to interfere with the establishment of an optimal treatment paradigm for bipolar depression.", "completion": "{\"entities\": [{\"text\": \"mania\", \"type\": \"Disease\"}, {\"text\": \"antidepressants\", \"type\": \"Chemical\"}, {\"text\": \"bipolar depression\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03395", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: There is still no proof of causative effect of VPA in patients with encephalopathy, but only of an association with an assumed causal relation.", "completion": "{\"entities\": [{\"text\": \"VPA\", \"type\": \"Chemical\"}, {\"text\": \"encephalopathy\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01246", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 2) relative to repeat users of second generation pills, whereas it was 1.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04573", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The initial dose of amantadine depressed locomotor activity in all mouse strains studied with the BALB / C mice being the most sensitive.", "completion": "{\"entities\": [{\"text\": \"amantadine\", \"type\": \"Chemical\"}, {\"text\": \"depressed\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01538", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cauda equina syndrome after epidural steroid injection: a case report.", "completion": "{\"entities\": [{\"text\": \"Cauda equina syndrome\", \"type\": \"Disease\"}, {\"text\": \"steroid\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-02542", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Intravenous inoculation of 4.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02500", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Furthermore, it appears that striatal - resident microglia respond to METH", "completion": "{\"entities\": [{\"text\": \"METH\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03621", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In experimental animals excess deposition of collagen and glycoaminoglycans was observed in the subendothelial and medial layer of the aortic wall, together with prominent basal membrane substance around aortic smooth muscle cells.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01401", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 7 g / dl at 1, 2, 3 and 6 months post - CAB, respectively.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02505", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Here, we describe an eight - and - a - half - yr - old male renal transplant recipient with right BN.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-reassigned-03900", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This pathology resembles interstitial cystitis", "completion": "{\"entities\": [{\"text\": \"interstitial cystitis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00293", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Also, there appears to be an adaptation by the rats to the chronic ingestion of aspirin", "completion": "{\"entities\": [{\"text\": \"aspirin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01936", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Elevations in the serum GOT and GPT were maximum in the sedentary - isoproterenols and minimum in the exercise - controls.", "completion": "{\"entities\": [{\"text\": \"isoproterenols\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03707", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Paclitaxel / cisplatin is an effective first - line regimen for locoregionally advanced head and neck cancer and continued study is warranted.", "completion": "{\"entities\": [{\"text\": \"Paclitaxel\", \"type\": \"Chemical\"}, {\"text\": \"cisplatin\", \"type\": \"Chemical\"}, {\"text\": \"head and neck cancer\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-reassigned-00641", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Baboon syndrome induced by ketoconazole.", "completion": "{\"entities\": [{\"text\": \"Baboon syndrome\", \"type\": \"Disease\"}, {\"text\": \"ketoconazole\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02997", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Haematological adverse reactions associated with fatal outcome are rare during treatment with ciprofloxacin.", "completion": "{\"entities\": [{\"text\": \"ciprofloxacin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04488", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: L-arginine transport in humans with cortisol - induced hypertension.", "completion": "{\"entities\": [{\"text\": \"L-arginine\", \"type\": \"Chemical\"}, {\"text\": \"cortisol\", \"type\": \"Chemical\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04712", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Zyban caused significant neurological and cardiovascular toxicity in overdose", "completion": "{\"entities\": [{\"text\": \"Zyban\", \"type\": \"Chemical\"}, {\"text\": \"neurological and cardiovascular toxicity\", \"type\": \"Disease\"}, {\"text\": \"overdose\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01351", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Sensitivity to several convulsion endpoints induced by nicotine, carbachol, and neostigmine were significantly greater in WSR versus WSP mice.", "completion": "{\"entities\": [{\"text\": \"convulsion\", \"type\": \"Disease\"}, {\"text\": \"nicotine\", \"type\": \"Chemical\"}, {\"text\": \"carbachol\", \"type\": \"Chemical\"}, {\"text\": \"neostigmine\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02603", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: for 16 days in an inpatient, double - blind randomized trial.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00726", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 008 ). The Receiver Operative Characteristic Curve showed that OD > 1.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02494", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Mice in which the CX3CR1 gene has been deleted and replaced with a cDNA encoding enhanced green fluorescent protein (eGFP) were treated with METH and examined for striatal neurotoxicity.", "completion": "{\"entities\": [{\"text\": \"METH\", \"type\": \"Chemical\"}, {\"text\": \"neurotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00267", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5% of all the cases, the aetiology of the neuropathy was undetermined.", "completion": "{\"entities\": [{\"text\": \"neuropathy\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02351", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In this experimental study we used 30 Sprague - Dawley rats, 27 of which had gentamicin instilled into the middle ear.", "completion": "{\"entities\": [{\"text\": \"gentamicin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04532", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: To analyze the transformation patterns, we classified the exencephaly by size and shape of the exencephalic tissue into several types at E13.", "completion": "{\"entities\": [{\"text\": \"exencephaly\", \"type\": \"Disease\"}, {\"text\": \"exencephalic\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00100", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Arterial hypertension as a complication of prolonged ketoconazole treatment.", "completion": "{\"entities\": [{\"text\": \"hypertension\", \"type\": \"Disease\"}, {\"text\": \"ketoconazole\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03746", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CASE: A 58 - year - old man received an intracarotid injection of carboplatin for recurrent glioblastomas in his left temporal lobe.", "completion": "{\"entities\": [{\"text\": \"carboplatin\", \"type\": \"Chemical\"}, {\"text\": \"glioblastomas\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01282", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We suggest that repeated endothelial injury, including immunologic injury", "completion": "{\"entities\": [{\"text\": \"endothelial injury\", \"type\": \"Disease\"}, {\"text\": \"immunologic injury\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03936", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Myasthenia gravis caused by penicillamine and chloroquine therapy for rheumatoid arthritis.", "completion": "{\"entities\": [{\"text\": \"Myasthenia gravis\", \"type\": \"Disease\"}, {\"text\": \"penicillamine\", \"type\": \"Chemical\"}, {\"text\": \"chloroquine\", \"type\": \"Chemical\"}, {\"text\": \"rheumatoid arthritis\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-05164", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A decreased glutamate uptake was observed in the subcortical parts of animals treated with reserpine and haloperidol, compared to the control.", "completion": "{\"entities\": [{\"text\": \"glutamate\", \"type\": \"Chemical\"}, {\"text\": \"reserpine\", \"type\": \"Chemical\"}, {\"text\": \"haloperidol\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-05068", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: To clarify the mechanisms of FK 506 - induced hypertension, we studied the chronic effects of FK 506 on the synthesis of endothelin - 1 (ET - 1 ), the expression of mRNA of ET - 1 and endothelin - converting enzyme - 1 (ECE - 1 ), the endothelial nitric oxide synthase (eNOS) activity, and the expression of mRNA of eNOS and C - type natriuretic peptide (CNP) in rat blood vessels.", "completion": "{\"entities\": [{\"text\": \"FK 506\", \"type\": \"Chemical\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}, {\"text\": \"nitric oxide\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03490", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Concentrations of amphotericin B in plasma were not significantly different among the three groups at any time during the study.", "completion": "{\"entities\": [{\"text\": \"amphotericin B\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00416", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The potential for acetaminophen to produce cardiovascular toxicities is very low.", "completion": "{\"entities\": [{\"text\": \"acetaminophen\", \"type\": \"Chemical\"}, {\"text\": \"cardiovascular toxicities\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00801", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Because DTIs do not have reversal agents, surgical teams and transfusion services should remain aware of the possibility of massive transfusion events during anticoagulation with these agents.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00804", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Antituberculosis therapy (ATT )- associated acute liver failure (ATT - ALF) is the commonest drug - induced ALF in South Asia.", "completion": "{\"entities\": [{\"text\": \"Antituberculosis\", \"type\": \"Chemical\"}, {\"text\": \"acute liver failure\", \"type\": \"Disease\"}, {\"text\": \"ALF\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02583", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: We analyzed the clinical and laboratory information available for all 119 patients transplanted at the Washington Hospital Center between 1999 - 2003 for whom sirolimus was a component of their immunosuppressant regimen.", "completion": "{\"entities\": [{\"text\": \"sirolimus\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02715", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Attenuation of methamphetamine - induced nigrostriatal dopaminergic neurotoxicity in mice by lipopolysaccharide pretreatment.", "completion": "{\"entities\": [{\"text\": \"methamphetamine\", \"type\": \"Chemical\"}, {\"text\": \"neurotoxicity\", \"type\": \"Disease\"}, {\"text\": \"lipopolysaccharide\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03852", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It is suggested that in both situations disturbed reticulo - thalamic interactions are important in the pathogenesis of alpha coma.", "completion": "{\"entities\": [{\"text\": \"coma\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00706", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A nerve conduction study was consistent with severe sensorimotor axonal polyneuropathy.", "completion": "{\"entities\": [{\"text\": \"polyneuropathy\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02472", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 006 ). ACE inhibitor and angiotensin-releasing blocker (ARB) therapy reduced proteinuria development.", "completion": "{\"entities\": [{\"text\": \"ACE inhibitor\", \"type\": \"Chemical\"}, {\"text\": \"angiotensin-releasing blocker\", \"type\": \"Chemical\"}, {\"text\": \"ARB\", \"type\": \"Chemical\"}, {\"text\": \"proteinuria\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04799", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The antinociceptive effect of 3 alpha-tropyl 2-(p-bromophenyl)propionate [(+/-)- PG-9 ](10 - 40 mg kg - 1 s.", "completion": "{\"entities\": [{\"text\": \"3 alpha-tropyl 2-(p-bromophenyl)propionate\", \"type\": \"Chemical\"}, {\"text\": \"PG-9\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03677", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Since it takes three to 12 months to achieve maximal effects, those patients who are unable to continue the drug receive little benefit from it.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01682", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Adult male albino rats, treated with ISO (200 mg / kg, s.", "completion": "{\"entities\": [{\"text\": \"ISO\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05222", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Moreover, test conditions can impact upon other physiological responses to apomorphine such as drug - induced hypothermia.", "completion": "{\"entities\": [{\"text\": \"apomorphine\", \"type\": \"Chemical\"}, {\"text\": \"hypothermia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03403", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 46 %) developed severe progressive and bilateral sensorineural hearing loss.", "completion": "{\"entities\": [{\"text\": \"sensorineural hearing loss\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00886", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Clinical and experimental data published to date suggest several possible mechanisms by which cocaine may result in acute myocardial infarction.", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"acute myocardial infarction\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03673", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Incidence of neoplasms in patients with rheumatoid arthritis exposed to different treatment regimens.", "completion": "{\"entities\": [{\"text\": \"neoplasms\", \"type\": \"Disease\"}, {\"text\": \"rheumatoid arthritis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01780", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Evidence for an involvement of D1 and D2 dopamine receptors in mediating nicotine - induced hyperactivity in rats.", "completion": "{\"entities\": [{\"text\": \"dopamine\", \"type\": \"Chemical\"}, {\"text\": \"nicotine\", \"type\": \"Chemical\"}, {\"text\": \"hyperactivity\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02689", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We describe a 70 - year - old Hispanic woman who developed fulminant hepatic failure necessitating liver transplantation 10 weeks after conversion from simvastatin 40 mg / day to simvastatin 10 mg-ezetimibe 40 mg / day.", "completion": "{\"entities\": [{\"text\": \"fulminant hepatic failure\", \"type\": \"Disease\"}, {\"text\": \"simvastatin\", \"type\": \"Chemical\"}, {\"text\": \"simvastatin 10 mg-ezetimibe 40 mg\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01820", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Although mazindol - treated patients gained less weight and height than placebo - treated patients, no significant effect on IGF - I levels was observed.", "completion": "{\"entities\": [{\"text\": \"mazindol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03109", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Acute liver failure in two patients with regular alcohol consumption ingesting paracetamol at therapeutic dosage.", "completion": "{\"entities\": [{\"text\": \"Acute liver failure\", \"type\": \"Disease\"}, {\"text\": \"alcohol\", \"type\": \"Chemical\"}, {\"text\": \"paracetamol\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01661", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Drowsiness was common on clonidine, but generally resolved by 6 to 8 weeks.", "completion": "{\"entities\": [{\"text\": \"Drowsiness\", \"type\": \"Disease\"}, {\"text\": \"clonidine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00107", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Induction of intravascular coagulation and inhibition of fibrinolysis by injection of thrombin and tranexamic acid (AMCA) in the rat gives rise to pulmonary and renal insufficiency resembling that occurring after trauma or sepsis in man.", "completion": "{\"entities\": [{\"text\": \"intravascular coagulation\", \"type\": \"Disease\"}, {\"text\": \"tranexamic acid\", \"type\": \"Chemical\"}, {\"text\": \"AMCA\", \"type\": \"Chemical\"}, {\"text\": \"pulmonary and renal insufficiency\", \"type\": \"Disease\"}, {\"text\": \"trauma\", \"type\": \"Disease\"}, {\"text\": \"sepsis\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-reassigned-01597", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cephalothin - induced immune hemolytic anemia.", "completion": "{\"entities\": [{\"text\": \"Cephalothin\", \"type\": \"Chemical\"}, {\"text\": \"hemolytic anemia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03819", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: HMG CoA reductase inhibitors.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01652", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: OBJECTIVE: To examine the safety and tolerability of clonidine used alone or with methylphenidate in children with attention-deficit/hyperactivity disorder (ADHD ). METHOD: In a 16 - week multicenter, double - blind trial, 122 children with ADHD were randomly assigned to clonidine (n = 31 ), methylphenidate (n = 29 ), clonidine and methylphenidate (n = 32 ), or placebo (n = 30 ). Doses were flexibly titrated up to 0.", "completion": "{\"entities\": [{\"text\": \"clonidine\", \"type\": \"Chemical\"}, {\"text\": \"methylphenidate\", \"type\": \"Chemical\"}, {\"text\": \"attention-deficit/hyperactivity disorder\", \"type\": \"Disease\"}, {\"text\": \"ADHD\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00383", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: To evaluate the effect of prostaglandin E1 (PGE1) or trimethaphan (TMP) induced hypotension on epidural blood flow (EBF) during spinal surgery, EBF was measured using the heat clearance method in 30 patients who underwent postero - lateral interbody fusion under isoflurane anaesthesia.", "completion": "{\"entities\": [{\"text\": \"prostaglandin E1\", \"type\": \"Chemical\"}, {\"text\": \"PGE1\", \"type\": \"Chemical\"}, {\"text\": \"trimethaphan\", \"type\": \"Chemical\"}, {\"text\": \"TMP\", \"type\": \"Chemical\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}, {\"text\": \"isoflurane\", \"type\": \"Chemical\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-01129", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Reduction of heparan sulphate - associated anionic sites in the glomerular basement membrane of rats with streptozotocin - induced diabetic nephropathy.", "completion": "{\"entities\": [{\"text\": \"heparan sulphate\", \"type\": \"Chemical\"}, {\"text\": \"streptozotocin\", \"type\": \"Chemical\"}, {\"text\": \"diabetic nephropathy\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04640", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: On the next day he died, probably as a result of heart failure.", "completion": "{\"entities\": [{\"text\": \"heart failure\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05032", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Furthermore, glomerulosclerosis index was significantly increased in the nitrendipine - treated group compared with the hypertensive controls (0.", "completion": "{\"entities\": [{\"text\": \"glomerulosclerosis\", \"type\": \"Disease\"}, {\"text\": \"nitrendipine\", \"type\": \"Chemical\"}, {\"text\": \"hypertensive\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03365", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 8 - fold when coadministered with cinacalcet.", "completion": "{\"entities\": [{\"text\": \"cinacalcet\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04301", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BE - Induced seizures occurred more frequently and had significantly longer latencies than those induced by equimolar amounts of cocaine.", "completion": "{\"entities\": [{\"text\": \"BE\", \"type\": \"Chemical\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04439", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: QTLs for susceptibility to pilocarpine - induced seizures, a model of temporal lobe epilepsy, have not been reported, and CSS have not previously been used to localize seizure susceptibility genes.", "completion": "{\"entities\": [{\"text\": \"pilocarpine\", \"type\": \"Chemical\"}, {\"text\": \"seizure\", \"type\": \"Disease\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}, {\"text\": \"temporal lobe epilepsy\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01839", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 1 %), malignant neoplasms (11.", "completion": "{\"entities\": [{\"text\": \"neoplasms\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01015", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Allergic reaction to 5-fluorouracil infusion.", "completion": "{\"entities\": [{\"text\": \"Allergic reaction\", \"type\": \"Disease\"}, {\"text\": \"5-fluorouracil\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01452", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 mL / 100 g bodyweight per day, orally for 30 days, prevented the increase in lipid peroxidation and activity of marker enzymes observed in isoproterenol - induced rats (85 mg kg (- 1) s.", "completion": "{\"entities\": [{\"text\": \"isoproterenol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02090", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Drug - associated acute - onset vanishing bile duct and Stevens-Johnson syndromes in a child.", "completion": "{\"entities\": [{\"text\": \"vanishing bile duct\", \"type\": \"Disease\"}, {\"text\": \"Stevens-Johnson syndromes\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01394", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Patients with stage D2 - 3 disease, abnormal hemoglobin level or renal and liver function tests that were higher than the upper limits were excluded from the study.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04744", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Older age was significantly correlated with the CHF development; with median ages for the entire group and for patients developing CHF of 45 and 59, respectively.", "completion": "{\"entities\": [{\"text\": \"CHF\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02424", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Maltolyl p-coumarate was found to attenuate cognitive deficits in both rat models using passive avoidance test and to reduce apoptotic cell death observed in the hippocampus of the amyloid beta peptide(1-42) - infused rats.", "completion": "{\"entities\": [{\"text\": \"Maltolyl p-coumarate\", \"type\": \"Chemical\"}, {\"text\": \"cognitive deficits\", \"type\": \"Disease\"}, {\"text\": \"amyloid beta peptide(1-42)\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02001", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Despite this, the drop - out rate was low.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01273", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Peritubular capillary basement membrane reduplication in allografts and native kidney disease: a clinicopathologic study of 278 consecutive renal specimens.", "completion": "{\"entities\": [{\"text\": \"kidney disease\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04205", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The arrhythmias were temporally related to cimetidine administration, disappeared after dechallenge, and did not recur during ranitidine treatment.", "completion": "{\"entities\": [{\"text\": \"arrhythmias\", \"type\": \"Disease\"}, {\"text\": \"cimetidine\", \"type\": \"Chemical\"}, {\"text\": \"ranitidine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03153", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thirty - five consecutive chemotherapy - naive patients with Stage IV NSCLC and an Eastern Cooperative Oncology Group performance status of 0 - 2 were treated with a combination of paclitaxel (135 mg / m (2) given intravenously in 3 hours) on Day 1, cisplatin (120 mg / m (2) given intravenously in 6 hours) on Day 1, and gemcitabine (800 mg / m (2) given intravenously in 30 minutes) on Days 1 and 8, every 4 weeks.", "completion": "{\"entities\": [{\"text\": \"NSCLC\", \"type\": \"Disease\"}, {\"text\": \"paclitaxel\", \"type\": \"Chemical\"}, {\"text\": \"cisplatin\", \"type\": \"Chemical\"}, {\"text\": \"gemcitabine\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04324", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Ten patients with acute transmural myocardial infarctions received intravenous nitroglycerin, sufficient to reduce mean arterial pressure from 107 +/- 6 to 85 +/- 6 mm Hg (P less than 0.", "completion": "{\"entities\": [{\"text\": \"myocardial infarctions\", \"type\": \"Disease\"}, {\"text\": \"nitroglycerin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04157", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 619) compared with all placebo patients (n / N = 62 / 92 and 14 / 92, respectively ). There was no correlation between SBP change and outcome.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04230", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 developed hind - limb paralysis.", "completion": "{\"entities\": [{\"text\": \"paralysis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02733", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05) without reducing albuminuria (617 +/- 50 vs.", "completion": "{\"entities\": [{\"text\": \"albuminuria\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02614", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Modafinil was associated with increased daytime sleep latency, as measured by the Multiple Sleep Latency Test, and a nearly significant decrease in subjective daytime sleepiness.", "completion": "{\"entities\": [{\"text\": \"Modafinil\", \"type\": \"Chemical\"}, {\"text\": \"daytime sleepiness\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02016", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 03 mEq .). Of the 19 patients without sodium bicarbonate added to the medication 11 (58 %) complained of penile pain due to the medication, while only 1 of the 19 men (5 %) who received sodium bicarbonate complained of penile pain.", "completion": "{\"entities\": [{\"text\": \"sodium bicarbonate\", \"type\": \"Chemical\"}, {\"text\": \"penile pain\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03264", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It is suggested that sevoflurane reduces the convulsive effect of lidocaine toxicity but carries some risk due to circulatory depression", "completion": "{\"entities\": [{\"text\": \"sevoflurane\", \"type\": \"Chemical\"}, {\"text\": \"convulsive\", \"type\": \"Disease\"}, {\"text\": \"lidocaine\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}, {\"text\": \"depression\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-01485", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Ceftriaxone - associated biliary pseudolithiasis in paediatric surgical patients.", "completion": "{\"entities\": [{\"text\": \"Ceftriaxone\", \"type\": \"Chemical\"}, {\"text\": \"biliary pseudolithiasis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00537", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The risk of myocardial infarction was similar among women who used oral contraceptives", "completion": "{\"entities\": [{\"text\": \"myocardial infarction\", \"type\": \"Disease\"}, {\"text\": \"oral contraceptives\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-01740", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Asterixis induced by carbamazepine therapy.", "completion": "{\"entities\": [{\"text\": \"Asterixis\", \"type\": \"Disease\"}, {\"text\": \"carbamazepine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01674", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Of concern was the occurrence of four thromboembolic events.", "completion": "{\"entities\": [{\"text\": \"thromboembolic\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01504", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: Thirty - nine postmenopausal women with osteopenia or osteoporosis were included in this prospective, controlled clinical study.", "completion": "{\"entities\": [{\"text\": \"osteopenia\", \"type\": \"Disease\"}, {\"text\": \"osteoporosis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03348", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 2 %) of the gentamicin - treated patients had renal failure.", "completion": "{\"entities\": [{\"text\": \"gentamicin\", \"type\": \"Chemical\"}, {\"text\": \"renal failure\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03022", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, no study in the literature has reported the use of a statistical model to analyze the variables that influence outcome.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01636", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: We report on the manifestation of a levetiracetam (LEV )- induced encephalopathy.", "completion": "{\"entities\": [{\"text\": \"levetiracetam\", \"type\": \"Chemical\"}, {\"text\": \"LEV\", \"type\": \"Chemical\"}, {\"text\": \"encephalopathy\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00997", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cerebral blood flow and cerebral metabolic rate for oxygen were measured during isoflurane - induced hypotension in 10 patients subjected to craniotomy for clipping of a cerebral aneurysm.", "completion": "{\"entities\": [{\"text\": \"oxygen\", \"type\": \"Chemical\"}, {\"text\": \"isoflurane\", \"type\": \"Chemical\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}, {\"text\": \"cerebral aneurysm\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00651", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 001 ). Before conversion 8 (32 %) patients had no proteinuria, whereas afterwards all patients had proteinuria.", "completion": "{\"entities\": [{\"text\": \"proteinuria\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05010", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Flestolol is metabolized by plasma esterases and has an elimination half - life of approximately 6.", "completion": "{\"entities\": [{\"text\": \"Flestolol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01288", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Moreover, post - treatment with LR132 prevented cocaine - induced lethality in a significant proportion of animals.", "completion": "{\"entities\": [{\"text\": \"LR132\", \"type\": \"Chemical\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01508", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Relationship between those markers and demographic characteristics were investigated.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03187", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Brain CT revealed a periventricular low density area in the frontal white matter and moderate dilatation of the lateral ventricles especially at the bilateral anterior horns.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03513", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05) and ventricular ectopic beats (P less than 0.", "completion": "{\"entities\": [{\"text\": \"ventricular ectopic beats\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03344", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Gentamicin sulfate and tobramycin sulfate continue to demonstrate ototoxicity and nephrotoxicity in both animal and clinical studies.", "completion": "{\"entities\": [{\"text\": \"Gentamicin sulfate\", \"type\": \"Chemical\"}, {\"text\": \"tobramycin sulfate\", \"type\": \"Chemical\"}, {\"text\": \"ototoxicity\", \"type\": \"Disease\"}, {\"text\": \"nephrotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02252", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Sub - chronic low dose gamma-vinyl GABA (vigabatrin) inhibits cocaine - induced increases in nucleus accumbens dopamine.", "completion": "{\"entities\": [{\"text\": \"gamma-vinyl GABA\", \"type\": \"Chemical\"}, {\"text\": \"vigabatrin\", \"type\": \"Chemical\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01390", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: To determine the onset and extent of combined androgen blockade (CAB )- induced anemia in prostate cancer patients without bone involvement.", "completion": "{\"entities\": [{\"text\": \"anemia\", \"type\": \"Disease\"}, {\"text\": \"prostate cancer\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04871", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 9 pounds, and they smoked a mean of 25.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04810", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Affinity profiles of (+/-)- PG-9 for muscarinic receptor subtypes, determined by functional studies (rabbit vas deferens for M1, guinea pig atrium for M2, guinea pig ileum for M3 and immature guinea pig uterus for putative M4 ), have shown an M4 / M1 selectivity ratio of 10.", "completion": "{\"entities\": [{\"text\": \"PG-9\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02782", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The objective of this study was to report our experience concerning the effectiveness of the prophylactic administration of lamivudine in hepatitis B virus surface antigen (HBs Ag) positive patients with rheumatologic disease.", "completion": "{\"entities\": [{\"text\": \"lamivudine\", \"type\": \"Chemical\"}, {\"text\": \"hepatitis B virus surface antigen\", \"type\": \"Chemical\"}, {\"text\": \"HBs Ag\", \"type\": \"Chemical\"}, {\"text\": \"rheumatologic disease\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-05214", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Amnesia produced by scopolamine and cycloheximide were reversed by morphine given 30 min before the test trial (pre - test ), and pre - test morphine also facilitated the memory retrieval in the animals administered naloxone during the training trial.", "completion": "{\"entities\": [{\"text\": \"Amnesia\", \"type\": \"Disease\"}, {\"text\": \"scopolamine\", \"type\": \"Chemical\"}, {\"text\": \"cycloheximide\", \"type\": \"Chemical\"}, {\"text\": \"morphine\", \"type\": \"Chemical\"}, {\"text\": \"naloxone\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-04194", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Based on nonoverdose pharmacokinetics and pharmacodynamics of venlafaxine and the potential risks of available interventions, no emergent therapy was instituted.", "completion": "{\"entities\": [{\"text\": \"venlafaxine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00968", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Drug - induced hepatotoxicity, although common, has been reported only infrequently with sulfonylureas.", "completion": "{\"entities\": [{\"text\": \"hepatotoxicity\", \"type\": \"Disease\"}, {\"text\": \"sulfonylureas\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01422", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The protective action of subcutaneously (SC) administered antidotes or their combinations in DFP (2.", "completion": "{\"entities\": [{\"text\": \"DFP\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04631", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Bradycardia, cholinergic symptoms and asystole occurred.", "completion": "{\"entities\": [{\"text\": \"Bradycardia\", \"type\": \"Disease\"}, {\"text\": \"asystole\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00044", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Fusidic acid was administered orally in a dose of 500 mg t.", "completion": "{\"entities\": [{\"text\": \"Fusidic acid\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03568", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The Calcineurin - inhibitor Induced Pain Syndrome (CIPS) is a rare but severe side effect of cyclosporine or tacrolimus and is accurately diagnosed by its typical presentation, magnetic resonance imaging and bone scans.", "completion": "{\"entities\": [{\"text\": \"Pain\", \"type\": \"Disease\"}, {\"text\": \"CIPS\", \"type\": \"Disease\"}, {\"text\": \"cyclosporine\", \"type\": \"Chemical\"}, {\"text\": \"tacrolimus\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03794", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The level of pyridoxal in the blood was normal during the periods of relapse.", "completion": "{\"entities\": [{\"text\": \"pyridoxal\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04763", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 4 %, and she had a positive direct Coombs antiglobulin test and an elevated indirect bilirubin.", "completion": "{\"entities\": [{\"text\": \"bilirubin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04266", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: At 6 h after injection, serum prolactin levels were still considerably lower than in controls.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04447", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This approach provides a framework for identifying potentially novel homologous candidate genes for human temporal lobe epilepsy", "completion": "{\"entities\": [{\"text\": \"temporal lobe epilepsy\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03978", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0mg / kg for piroxicam and 0.", "completion": "{\"entities\": [{\"text\": \"piroxicam\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00758", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Elevated atherosclerotic parameters, such as serum calcium, total cholesterol and low - density lipoprotein concentration were obtained in atherosclerotic rats.", "completion": "{\"entities\": [{\"text\": \"atherosclerotic\", \"type\": \"Disease\"}, {\"text\": \"calcium\", \"type\": \"Chemical\"}, {\"text\": \"cholesterol\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-reassigned-01061", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: All patients received succinylcholine 1.", "completion": "{\"entities\": [{\"text\": \"succinylcholine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02985", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: SETTING: National Institutes of Health clinical research center.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04253", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These observations indicate that initial hopes that sulindac", "completion": "{\"entities\": [{\"text\": \"sulindac\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04857", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A significant decrease in neuronal density of the hippocampal hilar formation was identified in vehicle - and PDTC - treated rats following status epilepticus.", "completion": "{\"entities\": [{\"text\": \"PDTC\", \"type\": \"Chemical\"}, {\"text\": \"status epilepticus\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03401", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Risk factors of sensorineural hearing loss in preterm infants.", "completion": "{\"entities\": [{\"text\": \"sensorineural hearing loss\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03940", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Two patients developed acute tubular necrosis, characterized clinically by acute oliguric renal failure, while they were receiving a combination of cephalothin sodium and gentamicin sulfate therapy.", "completion": "{\"entities\": [{\"text\": \"acute tubular necrosis\", \"type\": \"Disease\"}, {\"text\": \"oliguric renal failure\", \"type\": \"Disease\"}, {\"text\": \"cephalothin sodium\", \"type\": \"Chemical\"}, {\"text\": \"gentamicin sulfate\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01680", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Effect of green tea and vitamin E combination in isoproterenol induced myocardial infarction in rats.", "completion": "{\"entities\": [{\"text\": \"green tea\", \"type\": \"Chemical\"}, {\"text\": \"vitamin E\", \"type\": \"Chemical\"}, {\"text\": \"isoproterenol\", \"type\": \"Chemical\"}, {\"text\": \"myocardial infarction\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02673", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 001) and decreased thymus (P < 0.001) and bodyweights (P \"< 0.", "completion": "{\"entities\": [{\"text\": \"decreased thymus (P < 0.001) and bodyweights\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02995", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Sublingual UM-272 converted ventricular tachycardia", "completion": "{\"entities\": [{\"text\": \"UM-272\", \"type\": \"Chemical\"}, {\"text\": \"ventricular tachycardia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01409", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 g / dl after 3 months of CAB (p = 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03399", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These children were older and were more likely to have undergone recent bowel surgery than are other children with this condition.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01378", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 08) for CPA / EE use compared with an OR (adj) of 2.", "completion": "{\"entities\": [{\"text\": \"CPA\", \"type\": \"Chemical\"}, {\"text\": \"EE\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03587", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The full syndrome of subacute myelo-optic neuropathy", "completion": "{\"entities\": [{\"text\": \"myelo-optic neuropathy\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02353", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Its effect was determined in terms of attenuation of hearing loss, measured by shifts in the auditory brainstem response threshold.", "completion": "{\"entities\": [{\"text\": \"hearing loss\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03912", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This shunt of blood via a patent foramen ovale occurred in the presence of a normal pulmonary artery pressure, and was probably precipitated by a propafenone overdose.", "completion": "{\"entities\": [{\"text\": \"patent foramen ovale\", \"type\": \"Disease\"}, {\"text\": \"propafenone\", \"type\": \"Chemical\"}, {\"text\": \"overdose\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04730", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: The changes in pain thresholds were determined using mechanical stimuli -- the modification of the classic paw withdrawal test described by Randall - Selitto.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04753", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Absences were aggravated in both cases where vigabatrin was added on to concurrent treatment.", "completion": "{\"entities\": [{\"text\": \"vigabatrin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04113", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 mEq / L) or renal insufficiency (Cr > or = 2.", "completion": "{\"entities\": [{\"text\": \"renal insufficiency\", \"type\": \"Disease\"}, {\"text\": \"Cr\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01093", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The patient was treated with methylprednisolone and gradually improved.", "completion": "{\"entities\": [{\"text\": \"methylprednisolone\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00679", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In contrast to controls, methoctramine increased -- instead of decreased -- the tonic responses at high frequencies.", "completion": "{\"entities\": [{\"text\": \"methoctramine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01214", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thirteen biopsies were performed from stable functioning renal allografts with informed consent (nonepisode biopsy) and the other 13 were from dysfunctional renal allografts with a clinical indication for biopsy (episode biopsy ). RESULTS: The main pathologic diagnoses (some overlap) were acute rejection (AR; n = 4 ), chronic rejection (CR; n = 5 ), AR + CR (n = 4 ), recurrent IgA nephropathy (n = 5 ), normal findings (n = 2 ), minimal - type chronic FK506 nephropathy (n = 9 ), and mild - type FK506 nephropathy (n = 11 ). Of the nonepisode biopsies, 7 and 4 biopsies showed minimal - type and mild - type chronic FK506 nephropathy, respectively.", "completion": "{\"entities\": [{\"text\": \"IgA nephropathy\", \"type\": \"Disease\"}, {\"text\": \"nephropathy\", \"type\": \"Disease\"}, {\"text\": \"FK506\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04535", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It was found that the transformation of exencephalic tissue was not simply size - dependent, and all cases of anencephaly at E18.", "completion": "{\"entities\": [{\"text\": \"exencephalic\", \"type\": \"Disease\"}, {\"text\": \"anencephaly\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03154", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Although responding patients were scheduled to receive consolidation radiotherapy and 24 patients received preplanned second - line chemotherapy after disease progression, the response and toxicity rates reported refer only to the chemotherapy regimen given.", "completion": "{\"entities\": [{\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03106", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The increase in dP / dtejc during infusion of dobutamine in this group was severely impaired as compared to the non - ischemic group.", "completion": "{\"entities\": [{\"text\": \"dobutamine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01930", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the other infant cross - sectional echocardiography provided reassurance that the infant did not have Ebstein's anomaly.", "completion": "{\"entities\": [{\"text\": \"Ebstein's anomaly\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03255", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, there was no significant difference in the lidocaine concentrations measured when the systolic blood pressure became 70 mmHg.", "completion": "{\"entities\": [{\"text\": \"lidocaine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04396", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Chronic hyperprolactinemia induced by the dopamine antagonist sulpiride caused a 40% reduction LH pulse frequency in ovariectomized rats, but only in the presence of chronic low levels of estradiol.", "completion": "{\"entities\": [{\"text\": \"hyperprolactinemia\", \"type\": \"Disease\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}, {\"text\": \"sulpiride\", \"type\": \"Chemical\"}, {\"text\": \"estradiol\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04441", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Three hundred fifty - five adult male CSS mice, 58 B6, and 39 A / J were tested for susceptibility to pilocarpine - induced seizures.", "completion": "{\"entities\": [{\"text\": \"pilocarpine\", \"type\": \"Chemical\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03437", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This study is the first to demonstrate that impairment of hepatocyte TJs occurs heterogenously in the liver lobule after BDL and suggests that BDL and EE", "completion": "{\"entities\": [{\"text\": \"EE\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02136", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the cardiovascular system, NO is involved in the regulation of a variety of functions.", "completion": "{\"entities\": [{\"text\": \"NO\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01478", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 3 ), endometrial hyperplasia (RR 1.", "completion": "{\"entities\": [{\"text\": \"endometrial hyperplasia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00786", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It has been consistently shown that ecstasy users display impairments in learning and memory performance.", "completion": "{\"entities\": [{\"text\": \"ecstasy\", \"type\": \"Chemical\"}, {\"text\": \"impairments in learning and memory\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05192", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Puromycin aminonucleoside nephrosis was induced by single intraperitoneal injection of puromycin aminonucleoside (PAN, 20 mg / 100g BW ). Tissues were analyzed at 0, 5, 7, 11, 21, 45, 80 and 126 days after PAN injection so as to include both the acute phase of proteinuria associated with foot process effacement (days 5 - 11) and the chronic phase of proteinuria associated with glomerulosclerosis (days 45 - 126 ). At day 5, GLEPP1 protein and mRNA were reduced from the normal range (265.", "completion": "{\"entities\": [{\"text\": \"Puromycin aminonucleoside\", \"type\": \"Chemical\"}, {\"text\": \"nephrosis\", \"type\": \"Disease\"}, {\"text\": \"puromycin aminonucleoside\", \"type\": \"Chemical\"}, {\"text\": \"PAN\", \"type\": \"Chemical\"}, {\"text\": \"proteinuria\", \"type\": \"Disease\"}, {\"text\": \"glomerulosclerosis\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-02552", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A 61 - year - old Japanese man with nephrotic syndrome due to focal segmental glomerulosclerosis was initially responding well to steroid therapy.", "completion": "{\"entities\": [{\"text\": \"nephrotic syndrome\", \"type\": \"Disease\"}, {\"text\": \"focal segmental glomerulosclerosis\", \"type\": \"Disease\"}, {\"text\": \"steroid\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02035", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Long - term intragastric application of the antiepileptic drug sodium valproate (Vupral\" Polfa \") at the effective dose of 200 mg / kg b.", "completion": "{\"entities\": [{\"text\": \"sodium valproate\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00928", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: e ., myocardial and kidney injury) were evaluated by functional / physiological assays and by morphological techniques.", "completion": "{\"entities\": [{\"text\": \"myocardial and kidney injury\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00343", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This study supports the role of lipid peroxidation in mediating the proteinuric injury in PAN nephropathy", "completion": "{\"entities\": [{\"text\": \"proteinuric injury\", \"type\": \"Disease\"}, {\"text\": \"PAN\", \"type\": \"Chemical\"}, {\"text\": \"nephropathy\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04707", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Two patients developed severe cardiac arrhythmias, including one patient who was resuscitated following a cardiac arrest.", "completion": "{\"entities\": [{\"text\": \"cardiac arrhythmias\", \"type\": \"Disease\"}, {\"text\": \"cardiac arrest\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03919", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Amifostine subsequently was shown to protect normal tissues from the toxic effects of alkylating agents and cisplatin without decreasing the antitumor effect of the chemotherapy.", "completion": "{\"entities\": [{\"text\": \"Amifostine\", \"type\": \"Chemical\"}, {\"text\": \"alkylating agents\", \"type\": \"Chemical\"}, {\"text\": \"cisplatin\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04859", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These data might indicate that the generation of reactive oxygen species and activation of NF - kappaB plays a more central role in seizure - associated neuronal damage in the temporal cortex as compared to the hippocampal hilus.", "completion": "{\"entities\": [{\"text\": \"oxygen\", \"type\": \"Chemical\"}, {\"text\": \"seizure\", \"type\": \"Disease\"}, {\"text\": \"neuronal damage\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02483", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Synthesis of N-pyrimidinyl-2-phenoxyacetamides as adenosine A2A receptor antagonists.", "completion": "{\"entities\": [{\"text\": \"N-pyrimidinyl-2-phenoxyacetamides\", \"type\": \"Chemical\"}, {\"text\": \"adenosine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00085", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The data demonstrate that CAA after i.", "completion": "{\"entities\": [{\"text\": \"CAA\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00556", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Hepatitis may develop weeks after discontinuation of the drug and may run a prolonged course, but complete remission was observed in all reported cases.", "completion": "{\"entities\": [{\"text\": \"Hepatitis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00355", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A history of angioedema secondary to lisinopril therapy was elicited.", "completion": "{\"entities\": [{\"text\": \"angioedema\", \"type\": \"Disease\"}, {\"text\": \"lisinopril\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01799", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Reduction in injection pain using buffered lidocaine as a local anesthetic before cardiac catheterization.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"lidocaine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04605", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Echocardiographic Doppler studies were performed before infusion and after 15 min of infusion at each rate.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02267", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 014 - unit collagenase was adequate to detect ICH deterioration.", "completion": "{\"entities\": [{\"text\": \"ICH\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-reassigned-01280", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 001) and Glu (p less than 0.", "completion": "{\"entities\": [{\"text\": \"Glu\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02177", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It tended to reduce VAS scores of spontaneous pain but had no effect on evoked pain.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02557", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 8 g with acute renal failure.", "completion": "{\"entities\": [{\"text\": \"acute renal failure\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01741", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This case emphasizes the possibility that HUS in adults is not invariably irreversible and that, despite prolonged oliguria, recovery of renal function can be obtained.", "completion": "{\"entities\": [{\"text\": \"HUS\", \"type\": \"Disease\"}, {\"text\": \"oliguria\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02489", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Methamphetamine (METH) damages dopamine (DA) nerve endings by a process that has been linked to microglial activation but the signaling pathways that mediate this response have not yet been delineated.", "completion": "{\"entities\": [{\"text\": \"Methamphetamine\", \"type\": \"Chemical\"}, {\"text\": \"METH\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}, {\"text\": \"DA\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02516", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A second echocardiography was performed (median interval: 13 months) after pergolide withdrawal (n = 10 patients ). Controls were age - and sex - matched non - PD patients referred to the cardiology department.", "completion": "{\"entities\": [{\"text\": \"pergolide\", \"type\": \"Chemical\"}, {\"text\": \"PD\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03308", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Low - dose haloperidol did not differ from placebo on any measure of efficacy or side effects.", "completion": "{\"entities\": [{\"text\": \"haloperidol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02847", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The strong burning pain decayed exponentially within a few minutes.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04614", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cardiac arrhythmias have frequently been reported in association with respiratory failure.", "completion": "{\"entities\": [{\"text\": \"Cardiac arrhythmias\", \"type\": \"Disease\"}, {\"text\": \"respiratory failure\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01041", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: His bundle recordings showed an atrial tachycardia with intermittent exit block and greatly prolonged BH and HV intervals (40 and 100 msec, respectively ). Thirty days after amiodarone discontinuation, His bundle electrograms showed atrial flutter without intra - Hisian or infra - Hisian delay.", "completion": "{\"entities\": [{\"text\": \"atrial tachycardia\", \"type\": \"Disease\"}, {\"text\": \"amiodarone\", \"type\": \"Chemical\"}, {\"text\": \"atrial flutter\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04417", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Ritonavir increased the expression of the scavenger receptor, CD36 mRNA, responsible for the uptake of LDL.", "completion": "{\"entities\": [{\"text\": \"Ritonavir\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-reassigned-00699", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Hannover Wistar rats were dosed with 1.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01175", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Seven patients had previously received radiotherapy and seven had received hormone therapy.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02662", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Role of xanthine oxidase in dexamethasone - induced hypertension in rats.", "completion": "{\"entities\": [{\"text\": \"xanthine\", \"type\": \"Chemical\"}, {\"text\": \"dexamethasone\", \"type\": \"Chemical\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01250", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We conclude that second and third generation agents are associated with equivalent risks of VTE when the same agent is used repeatedly after interruption periods or when users are switched between the two generations of pills.", "completion": "{\"entities\": [{\"text\": \"VTE\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03357", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Neuroprotection rendered by MPEP may be associated with the reduction of the methamphetamine - induced dopamine efflux in the striatum due to the blockade of extrastriatal mGluR5, and with a decrease in hyperthermia", "completion": "{\"entities\": [{\"text\": \"MPEP\", \"type\": \"Chemical\"}, {\"text\": \"methamphetamine\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}, {\"text\": \"hyperthermia\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04920", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Analgesic effect of intravenous ketamine in cancer patients on morphine therapy: a randomized, controlled, double - blind, crossover, double - dose study.", "completion": "{\"entities\": [{\"text\": \"ketamine\", \"type\": \"Chemical\"}, {\"text\": \"cancer\", \"type\": \"Disease\"}, {\"text\": \"morphine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02388", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: No direct comparisons exist of the renal tolerability of the low - osmolality contrast medium iopamidol with that of the iso - osmolality contrast medium iodixanol in high - risk patients.", "completion": "{\"entities\": [{\"text\": \"contrast medium\", \"type\": \"Chemical\"}, {\"text\": \"iopamidol\", \"type\": \"Chemical\"}, {\"text\": \"iodixanol\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04195", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: The venlafaxine overdose in our patient resulted in a single episode of generalized seizure", "completion": "{\"entities\": [{\"text\": \"venlafaxine\", \"type\": \"Chemical\"}, {\"text\": \"overdose\", \"type\": \"Disease\"}, {\"text\": \"seizure\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03842", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Following the initial period of therapy, emerging difficulties require a reassessment of therapeutic approaches, such as dosage adjustment or introduction of a dopamine agonist.", "completion": "{\"entities\": [{\"text\": \"dopamine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01275", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: We examined 278 consecutive renal specimens (from 135 transplants and 143 native kidneys) for ultrastructural evidence of PTCR.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04071", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Hemodynamic parameters and lead II electrocardiograph were monitored and recorded continuously.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03351", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The aim of this study was to examine the role of metabotropic glutamate receptor 5 (mGluR5) in the toxic action of methamphetamine on dopaminergic neurones in rats.", "completion": "{\"entities\": [{\"text\": \"glutamate\", \"type\": \"Chemical\"}, {\"text\": \"methamphetamine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01130", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Heparan sulphate - associated anionic sites in the glomerular basement membrane were studied in rats 8 months after induction of diabetes by streptozotocin and in age - adn sex - matched control rats, employing the cationic dye cuprolinic blue.", "completion": "{\"entities\": [{\"text\": \"Heparan sulphate\", \"type\": \"Chemical\"}, {\"text\": \"diabetes\", \"type\": \"Disease\"}, {\"text\": \"streptozotocin\", \"type\": \"Chemical\"}, {\"text\": \"cuprolinic blue\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01419", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Psychologists need to inquire about consumption of quinine", "completion": "{\"entities\": [{\"text\": \"quinine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03286", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Treatment with Ato improved endothelial function, reduced superoxide production and reduced SBP in Dex", "completion": "{\"entities\": [{\"text\": \"Ato\", \"type\": \"Chemical\"}, {\"text\": \"superoxide\", \"type\": \"Chemical\"}, {\"text\": \"Dex\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00477", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: There was a close parallel between the effect of vitamin D dose on artery calcification and the effect of vitamin D dose on the elevation of serum calcium, which suggests that vitamin D may induce artery calcification through its effect on serum calcium.", "completion": "{\"entities\": [{\"text\": \"vitamin D\", \"type\": \"Chemical\"}, {\"text\": \"artery calcification\", \"type\": \"Disease\"}, {\"text\": \"calcium\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01871", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The animals were mechanically ventilated to achieve normocarbia (PCO2 = 42 +/- 1 mmHg, mean +/- SE ). Following instrumentation, halothane was discontinued and alfentanil (125 mu / kg) administered iv during emergence from halothane anesthesia.", "completion": "{\"entities\": [{\"text\": \"halothane\", \"type\": \"Chemical\"}, {\"text\": \"alfentanil\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-03365", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Ischemic colitis and sumatriptan use.", "completion": "{\"entities\": [{\"text\": \"Ischemic colitis\", \"type\": \"Disease\"}, {\"text\": \"sumatriptan\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04197", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The effect of nifedipine on renal function in liver transplant recipients who were receiving tacrolimus was evaluated between January 1992 and January 1996.", "completion": "{\"entities\": [{\"text\": \"nifedipine\", \"type\": \"Chemical\"}, {\"text\": \"tacrolimus\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05180", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: All three had been diagnosed earlier with epilepsy, and their electroencephalogram (EEG) findings were abnormal.", "completion": "{\"entities\": [{\"text\": \"epilepsy\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00463", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: New chemotherapy combinations with higher activity and lower toxicity are needed for elderly patients with advanced NSCLC", "completion": "{\"entities\": [{\"text\": \"toxicity\", \"type\": \"Disease\"}, {\"text\": \"NSCLC\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01052", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In each group, SNP infusion resulted in an initial decrease in blood pressure from 86 torr and 83 torr, respectively, to 48 torr.", "completion": "{\"entities\": [{\"text\": \"SNP\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02231", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Simultaneous administration of morphine with metamizol resulted in a markedly antinociceptive potentiation and an increasing of the duration of action after a single (298 +/- 7 vs.", "completion": "{\"entities\": [{\"text\": \"morphine\", \"type\": \"Chemical\"}, {\"text\": \"metamizol\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01316", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Intravenous administration of prochlorperazine by 15 - minute infusion versus 2 - minute bolus does not affect the incidence of akathisia: a prospective, randomized, controlled trial.", "completion": "{\"entities\": [{\"text\": \"prochlorperazine\", \"type\": \"Chemical\"}, {\"text\": \"akathisia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04311", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: p .) dose of (+/-)- amphetamine hemisulfate, given to rats pretreated with iprindole, resulted in persistent depletion of dopamine in the striatum 1 week later.", "completion": "{\"entities\": [{\"text\": \"amphetamine\", \"type\": \"Chemical\"}, {\"text\": \"iprindole\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04738", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cardiac toxicity observed in association with high - dose cyclophosphamide - based chemotherapy for metastatic breast cancer.", "completion": "{\"entities\": [{\"text\": \"Cardiac toxicity\", \"type\": \"Disease\"}, {\"text\": \"cyclophosphamide\", \"type\": \"Chemical\"}, {\"text\": \"breast cancer\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00421", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The reports illustrate the need for clinicians to consider acetaminophen in patients with hypotension", "completion": "{\"entities\": [{\"text\": \"acetaminophen\", \"type\": \"Chemical\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02213", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In addition, its' presumed contribution to DNA repair may be another important attribute, which played a role in the chemoprevention process.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04736", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In streptozotocin - induced hyperalgesia, inducible NO synthase participates in pronociceptive activity of bradykinin, whereas in vincristine - induced hyperalgesia bradykinin seemed to activate neuronal NO synthase pathway.", "completion": "{\"entities\": [{\"text\": \"streptozotocin\", \"type\": \"Chemical\"}, {\"text\": \"hyperalgesia\", \"type\": \"Disease\"}, {\"text\": \"NO\", \"type\": \"Chemical\"}, {\"text\": \"bradykinin\", \"type\": \"Chemical\"}, {\"text\": \"vincristine\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-04388", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Because proteinuria is a major predictive factor of poor transplantation outcome, many studies focused on this adverse event during the past years.", "completion": "{\"entities\": [{\"text\": \"proteinuria\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03955", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: o ., respectively) reversed memory deficits induced by scopolamine and TRP depletion (10 mg / kg, i.", "completion": "{\"entities\": [{\"text\": \"memory deficits\", \"type\": \"Disease\"}, {\"text\": \"scopolamine\", \"type\": \"Chemical\"}, {\"text\": \"TRP\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02045", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Damage to the capillary was accompanied by marked damage to neuroglial cells, mainly to perivascular processes of astrocytes.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00672", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In cyclophosphamide - induced cystitis in the rat, detrusor function is impaired and the expression and effects of muscarinic receptors altered.", "completion": "{\"entities\": [{\"text\": \"cyclophosphamide\", \"type\": \"Chemical\"}, {\"text\": \"cystitis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02940", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: These data demonstrate direct and / or indirect drug - induced toxicity.", "completion": "{\"entities\": [{\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00461", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This age group had an increased risk of myelosuppression.", "completion": "{\"entities\": [{\"text\": \"myelosuppression\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03671", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 9 ). Other antibacterial agents that showed associations included erythromycins (2 defects ), penicillins (1 defect ), cephalosporins (1 defect ), and quinolones (1 defect ). CONCLUSIONS: Reassuringly, penicillins, erythromycins, and cephalosporins, although used commonly by pregnant women, were not associated with many birth defects.", "completion": "{\"entities\": [{\"text\": \"erythromycins\", \"type\": \"Chemical\"}, {\"text\": \"penicillins\", \"type\": \"Chemical\"}, {\"text\": \"cephalosporins\", \"type\": \"Chemical\"}, {\"text\": \"quinolones\", \"type\": \"Chemical\"}, {\"text\": \"birth defects\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-02901", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Ranitidine frequently is used for preventing peptic ulceration after renal transplantation.", "completion": "{\"entities\": [{\"text\": \"Ranitidine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00483", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHOD: The response of 44 patients meeting DSM - IV criteria for bipolar disorder to naturalistic treatment was assessed for at least 6 weeks using the Montgomery - Asberg Depression Rating Scale and the Bech - Rafaelson Mania Rating Scale.", "completion": "{\"entities\": [{\"text\": \"bipolar disorder\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03586", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Older subjects tended to display more side effects.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03769", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Optimising stroke prevention in non - valvular atrial fibrillation.", "completion": "{\"entities\": [{\"text\": \"stroke\", \"type\": \"Disease\"}, {\"text\": \"atrial fibrillation\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01434", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Atropine - MK801 did not offer any additional protection against DFP toxicity.", "completion": "{\"entities\": [{\"text\": \"Atropine\", \"type\": \"Chemical\"}, {\"text\": \"MK801\", \"type\": \"Chemical\"}, {\"text\": \"DFP\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00391", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After starting PGE1 or TMP, MAP and rate pressure product (RPP) decreased significantly compared with preinfusion values (P < 0.", "completion": "{\"entities\": [{\"text\": \"PGE1\", \"type\": \"Chemical\"}, {\"text\": \"TMP\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02230", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: On the 13th day, antinociceptive effects were assessed using a model of inflammatory nociception, pain - induced functional impairment model, and the charcoal meal test was used to evaluate the intestinal transit.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"charcoal\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00123", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Carbamazepine (CBZ ), a commonly used AED, has been implicated in some clinical studies.", "completion": "{\"entities\": [{\"text\": \"Carbamazepine\", \"type\": \"Chemical\"}, {\"text\": \"CBZ\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00251", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Calcium concentrations 1 day postpartum were higher in cows treated with vitamin D3 about 32 days prepartum (8.", "completion": "{\"entities\": [{\"text\": \"Calcium\", \"type\": \"Chemical\"}, {\"text\": \"vitamin D3\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02719", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Such systemic lipopolysaccharide treatment mitigated methamphetamine - induced striatal dopamine and 3,4-dihydroxyphenylacetic acid depletions in a dose - dependent manner.", "completion": "{\"entities\": [{\"text\": \"lipopolysaccharide\", \"type\": \"Chemical\"}, {\"text\": \"methamphetamine\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}, {\"text\": \"3,4-dihydroxyphenylacetic acid\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02600", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: OBJECTIVE: The purpose of the present study was to determine the effect of morning - dosed modafinil on sleep and daytime sleepiness in chronic cocaine users.", "completion": "{\"entities\": [{\"text\": \"modafinil\", \"type\": \"Chemical\"}, {\"text\": \"daytime sleepiness\", \"type\": \"Disease\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02467", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 88) at 24 months postswitch (p = 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04434", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Because such a compensatory mechanism most likely occurs to reduce injury to the brain from cytotoxic compounds, the present data substantiate the concept that MRP2 performs a protective role in the BBB.", "completion": "{\"entities\": [{\"text\": \"injury to the brain\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02625", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 4, respectively) and haloperidol (- 20.", "completion": "{\"entities\": [{\"text\": \"haloperidol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03371", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These data suggest that during concomitant treatment with cinacalcet", "completion": "{\"entities\": [{\"text\": \"cinacalcet\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02879", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Hydrogen cyanamide is a plant growth regulator used in agriculture to induce bud break in fruit trees.", "completion": "{\"entities\": [{\"text\": \"Hydrogen cyanamide\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03678", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Patients treated with alkylating agents have an increased risk of development of acute nonlymphocytic leukemia, and both alkylating agents and azathioprine are associated with the development of non-Hodgkin's lymphoma.", "completion": "{\"entities\": [{\"text\": \"alkylating agents\", \"type\": \"Chemical\"}, {\"text\": \"acute nonlymphocytic leukemia\", \"type\": \"Disease\"}, {\"text\": \"azathioprine\", \"type\": \"Chemical\"}, {\"text\": \"non-Hodgkin's lymphoma\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02613", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Comparison of slow - wave sleep time, total sleep time, and sleep latency in cocaine - dependent and healthy participants revealed a normalizing effect of modafinil in cocaine - dependent participants.", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"modafinil\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-02738", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Propylthiouracil - induced hepatic damage.", "completion": "{\"entities\": [{\"text\": \"Propylthiouracil\", \"type\": \"Chemical\"}, {\"text\": \"hepatic damage\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04536", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 resulted from embryos with a large amount of exencephalic tissue at E13.", "completion": "{\"entities\": [{\"text\": \"exencephalic\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03957", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: o ., respectively ). In conclusion, although Ro4368554 did not improve a time - related retention deficit, it reversed a cholinergic and a serotonergic memory deficit, suggesting that both mechanisms may be involved in the facilitation of object memory by Ro4368554 and, possibly, other 5-HT", "completion": "{\"entities\": [{\"text\": \"Ro4368554\", \"type\": \"Chemical\"}, {\"text\": \"memory deficit\", \"type\": \"Disease\"}, {\"text\": \"5-HT\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00536", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The results with respect to the use of third - generation oral contraceptives were inconclusive but suggested that the risk was lower than the risk associated with second - generation oral contraceptives.", "completion": "{\"entities\": [{\"text\": \"oral contraceptives\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04546", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cocaine was injected ip over a range of doses (50 - 100 mg / kg) and behavior was monitored for 20 minutes.", "completion": "{\"entities\": [{\"text\": \"Cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05117", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Two groups were compared in this study.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04340", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 01 ), with trends of elevation in CaCl(2) - untreated segments, as compared with NaCl - treated segments.", "completion": "{\"entities\": [{\"text\": \"CaCl(2)\", \"type\": \"Chemical\"}, {\"text\": \"NaCl\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03550", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Maximal cTnI (pg / ml) and cTnT levels were significantly increased in DOX rats compared with controls (p = 0.", "completion": "{\"entities\": [{\"text\": \"DOX\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01463", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 3 years, raloxifene was associated with an increased risk for venous thromboembolism (relative risk [RR] 2.", "completion": "{\"entities\": [{\"text\": \"raloxifene\", \"type\": \"Chemical\"}, {\"text\": \"venous thromboembolism\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03557", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0001 ). A significant relationship was observed between maximal cTnT and the extent of myocardial morphological changes, and between LV diameters / BW and histological findings.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00418", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This article describes two critically ill patients in whom transient episodes of hypotension reproducibly developed after administration of acetaminophen.", "completion": "{\"entities\": [{\"text\": \"critically ill\", \"type\": \"Disease\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}, {\"text\": \"acetaminophen\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00696", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Use of BZDs / RDs tended to be associated with a reduced ability to walk and shorter night - time sleep during the week prior to admission.", "completion": "{\"entities\": [{\"text\": \"BZDs\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04084", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In addition, a statistically significant reduction was also observed on the level of GABA and glycine but less than a drastic reduction of glutamate and aspartate level.", "completion": "{\"entities\": [{\"text\": \"GABA\", \"type\": \"Chemical\"}, {\"text\": \"glycine\", \"type\": \"Chemical\"}, {\"text\": \"glutamate\", \"type\": \"Chemical\"}, {\"text\": \"aspartate\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00904", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 8 hours with ipratropium and 2.", "completion": "{\"entities\": [{\"text\": \"ipratropium\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03832", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Lovastatin and simvastatin are both effective and well - tolerated agents for lowering elevated levels of serum cholesterol.", "completion": "{\"entities\": [{\"text\": \"Lovastatin\", \"type\": \"Chemical\"}, {\"text\": \"simvastatin\", \"type\": \"Chemical\"}, {\"text\": \"cholesterol\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-reassigned-05755", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: STUDY DESIGN: Retrospective case series.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03129", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Nine days later the patient' s creatine kinase had dropped to 1695 U / L and creatinine was 3.", "completion": "{\"entities\": [{\"text\": \"creatine\", \"type\": \"Chemical\"}, {\"text\": \"creatinine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02531", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pergolide was discontinued in 10 patients with valvular heart disease, resulting in a lower regurgitation grade (p = 0.", "completion": "{\"entities\": [{\"text\": \"Pergolide\", \"type\": \"Chemical\"}, {\"text\": \"valvular heart disease\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02284", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: We used computerized pharmacy records to identify all adult psychiatric inpatients treated with clozapine (1995 - 96 ), reviewed their medical records to score incidence and severity of delirium, and tested associations with potential risk factors.", "completion": "{\"entities\": [{\"text\": \"psychiatric\", \"type\": \"Disease\"}, {\"text\": \"clozapine\", \"type\": \"Chemical\"}, {\"text\": \"delirium\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02357", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cerebral vasculitis associated with amphetamine abuse is well documented, and in rare cases ischaemic stroke has been reported after methylphenidate intake in children.", "completion": "{\"entities\": [{\"text\": \"Cerebral vasculitis\", \"type\": \"Disease\"}, {\"text\": \"amphetamine abuse\", \"type\": \"Disease\"}, {\"text\": \"ischaemic stroke\", \"type\": \"Disease\"}, {\"text\": \"methylphenidate\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00894", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Finally, the contribution of a primary, thrombotic effect of cocaine", "completion": "{\"entities\": [{\"text\": \"thrombotic\", \"type\": \"Disease\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05060", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: p ., one hour ), an inhibitor of tyrosine hydroxylase, significantly decreased the activity - increasing effects of morphine.", "completion": "{\"entities\": [{\"text\": \"tyrosine\", \"type\": \"Chemical\"}, {\"text\": \"morphine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03459", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Subjects were 1210 inpatients with New York Heart Association (NYHA) functional class II and III.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01795", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Side effects occurred after both therapeutic and prophylactic intake and were graded from moderate to severe.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00464", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Warfarin - induced artery calcification is accelerated by growth and vitamin D.", "completion": "{\"entities\": [{\"text\": \"Warfarin\", \"type\": \"Chemical\"}, {\"text\": \"artery calcification\", \"type\": \"Disease\"}, {\"text\": \"vitamin D\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04630", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Minutes after oral administration, the patient developed nausea, sweating and hypotension, and finally collapsed.", "completion": "{\"entities\": [{\"text\": \"nausea\", \"type\": \"Disease\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03702", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Three patients had no change and disease progressed in two.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04078", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The protective role of salvianolic acid A against isoproterenol - induced myocardial damage was further confirmed by histopathological examination.", "completion": "{\"entities\": [{\"text\": \"salvianolic acid A\", \"type\": \"Chemical\"}, {\"text\": \"isoproterenol\", \"type\": \"Chemical\"}, {\"text\": \"myocardial damage\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02340", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Although most cases of antibiotic induced acute interstitial nephritis are benign and self - limited, some patients are at risk for permanent renal injury", "completion": "{\"entities\": [{\"text\": \"interstitial nephritis\", \"type\": \"Disease\"}, {\"text\": \"renal injury\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02156", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In isolated perfused heart preparations from isoproterenol - pretreated rats, the isoproterenol - induced maximal increase in left ventricular systolic pressure was significantly reduced, compared with saline - pretreated rats (the EC50 of the isoproterenol - induced increase in left ventricular systolic pressure was enhanced approximately 22 - fold ). These results show that 15 - day isoproterenol pretreatment not only abolished but reversed bromocriptine - induced tachycardia to bradycardia, an effect that is mainly related to further cardiac beta - adrenoceptor desensitization rather than to impairment of autonomic regulation of the heart.", "completion": "{\"entities\": [{\"text\": \"isoproterenol\", \"type\": \"Chemical\"}, {\"text\": \"bromocriptine\", \"type\": \"Chemical\"}, {\"text\": \"tachycardia\", \"type\": \"Disease\"}, {\"text\": \"bradycardia\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00981", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 7 mm Hg in the HEM group, compared with 9.", "completion": "{\"entities\": [{\"text\": \"HEM\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01050", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Control rats received halothane anesthesia (1 MAC) for one hour, followed by SNP infusion, 40 microgram / kg / min, for 30 min, followed by a 30 - min recovery period.", "completion": "{\"entities\": [{\"text\": \"halothane\", \"type\": \"Chemical\"}, {\"text\": \"SNP\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04914", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: injection of methyl beta-carboline-3-carboxylate (beta-CCM ), an inverse agonist of the GABA (A) receptor benzodiazepine site.", "completion": "{\"entities\": [{\"text\": \"methyl beta-carboline-3-carboxylate\", \"type\": \"Chemical\"}, {\"text\": \"beta-CCM\", \"type\": \"Chemical\"}, {\"text\": \"GABA\", \"type\": \"Chemical\"}, {\"text\": \"benzodiazepine\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03632", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Three patients developed congestive heart failure after the completion of chemotherapy.", "completion": "{\"entities\": [{\"text\": \"congestive heart failure\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01091", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CASE SUMMARY: A 13 - year - old boy was treated with ampicillin and gentamicin because of suspected septicemia.", "completion": "{\"entities\": [{\"text\": \"ampicillin\", \"type\": \"Chemical\"}, {\"text\": \"gentamicin\", \"type\": \"Chemical\"}, {\"text\": \"septicemia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-reassigned-02343", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: One patient had both.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04956", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: Low prevalences and effects of low testosterone and high prolactin in erectile dysfunction cannot justify their routine determination.", "completion": "{\"entities\": [{\"text\": \"testosterone\", \"type\": \"Chemical\"}, {\"text\": \"erectile dysfunction\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04722", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Also recorded were one case of pain of the vein, which required treatment, and two cases of hypotension.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03583", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the remaining cases, a combination of myelopathy, visual disturbance, and peripheral neuropathy was the most common manifestation.", "completion": "{\"entities\": [{\"text\": \"myelopathy\", \"type\": \"Disease\"}, {\"text\": \"visual disturbance\", \"type\": \"Disease\"}, {\"text\": \"peripheral neuropathy\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00701", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: One month previously, she had taken a single high dose of disulfiram (130 tablets of ALCOHOL STOP TAB, Shin - Poong Pharm.", "completion": "{\"entities\": [{\"text\": \"disulfiram\", \"type\": \"Chemical\"}, {\"text\": \"ALCOHOL\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01663", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Physicians prescribing clonidine should monitor for bradycardia and advise patients about the high likelihood of initial drowsiness", "completion": "{\"entities\": [{\"text\": \"clonidine\", \"type\": \"Chemical\"}, {\"text\": \"bradycardia\", \"type\": \"Disease\"}, {\"text\": \"drowsiness\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03748", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Various ocular symptoms and findings caused by carboplatin toxicity were seen.", "completion": "{\"entities\": [{\"text\": \"carboplatin\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01976", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Phenobarbitone - induced enlargement of the liver in the rat: its relationship to carbon tetrachloride - induced cirrhosis.", "completion": "{\"entities\": [{\"text\": \"Phenobarbitone\", \"type\": \"Chemical\"}, {\"text\": \"enlargement of the liver\", \"type\": \"Disease\"}, {\"text\": \"carbon tetrachloride\", \"type\": \"Chemical\"}, {\"text\": \"cirrhosis\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03103", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: The study group comprised 40 patients undergoing Sestamibi - SPECT / dobutamine stress test.", "completion": "{\"entities\": [{\"text\": \"Sestamibi\", \"type\": \"Chemical\"}, {\"text\": \"dobutamine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02757", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We determined the BChE activity and the BCHE genotype using molecular genetic methods, the duration of apnea, time to sufficient spontaneous ventilation and whether neuromuscular monitoring was used.", "completion": "{\"entities\": [{\"text\": \"apnea\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04957", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, cost - effective screening strategies recommended so far missed 40 to 50% of cases improved with endocrine therapy and the pituitary tumors.", "completion": "{\"entities\": [{\"text\": \"pituitary tumors\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02114", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The prevalence rate for CIMD was 12% at baseline.", "completion": "{\"entities\": [{\"text\": \"CIMD\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00456", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Six patients (12 %) had World Health Organization Grade 3 - 4 neutropenia, 2 patients (4 %) had Grade 3 - 4 thrombocytopenia, and 2 patients (4 %) had Grade 3 neurotoxicity.", "completion": "{\"entities\": [{\"text\": \"neutropenia\", \"type\": \"Disease\"}, {\"text\": \"thrombocytopenia\", \"type\": \"Disease\"}, {\"text\": \"neurotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03274", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: c .) or saline was started after 4 days in Ato - treated and non - treated rats and continued for 11 - 13 days.", "completion": "{\"entities\": [{\"text\": \"Ato\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00095", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Clotiazepam - induced acute hepatitis.", "completion": "{\"entities\": [{\"text\": \"Clotiazepam\", \"type\": \"Chemical\"}, {\"text\": \"hepatitis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00914", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This study shows that prolonged analgesic treatment in Fischer 344 rats causes progressive and irreversible damage to the interstitial matrix and type 1 interstitial cells leading to RPN", "completion": "{\"entities\": [{\"text\": \"RPN\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04315", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The prolonged depletion of dopamine in the striatum in mice, given multiple injections of methamphetamine, was also antagonized dose - dependently and completely by LY274614.", "completion": "{\"entities\": [{\"text\": \"dopamine\", \"type\": \"Chemical\"}, {\"text\": \"methamphetamine\", \"type\": \"Chemical\"}, {\"text\": \"LY274614\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02781", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Prophylactic use of lamivudine with chronic immunosuppressive therapy for rheumatologic disorders.", "completion": "{\"entities\": [{\"text\": \"lamivudine\", \"type\": \"Chemical\"}, {\"text\": \"rheumatologic disorders\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03137", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Phase II trial of vinorelbine in metastatic squamous cell esophageal carcinoma.", "completion": "{\"entities\": [{\"text\": \"vinorelbine\", \"type\": \"Chemical\"}, {\"text\": \"squamous cell esophageal carcinoma\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04841", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pharmacokinetic interactions of curcumin with phenobarbitone and carbamazepine were also studied.", "completion": "{\"entities\": [{\"text\": \"curcumin\", \"type\": \"Chemical\"}, {\"text\": \"phenobarbitone\", \"type\": \"Chemical\"}, {\"text\": \"carbamazepine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01689", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05) decrease in heart weight, serum marker enzymes, lipid peroxidation, Ca + 2 ATPase and a significant increase in the body weight, endogenous antioxidants, Na +/ K + ATPase and Mg + 2 ATPase when compared with ISO treated group and green tea or vitamin E alone treated groups.", "completion": "{\"entities\": [{\"text\": \"Ca\", \"type\": \"Chemical\"}, {\"text\": \"Na\", \"type\": \"Chemical\"}, {\"text\": \"K\", \"type\": \"Chemical\"}, {\"text\": \"Mg\", \"type\": \"Chemical\"}, {\"text\": \"ISO\", \"type\": \"Chemical\"}, {\"text\": \"green tea\", \"type\": \"Chemical\"}, {\"text\": \"vitamin E\", \"type\": \"Chemical\"}]}", "n_entities": 7}
{"ref": "bc5cdr-train-01899", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Since 18 of the 22 patients were initially receiving deferoxamine doses in excess of the commonly recommended 50 mg / kg per dose, therapy was restarted with lower doses, usually 50 mg / kg per dose or less depending on the degree of auditory abnormality, and with the exception of two cases no further toxicity was demonstrated.", "completion": "{\"entities\": [{\"text\": \"deferoxamine\", \"type\": \"Chemical\"}, {\"text\": \"auditory abnormality\", \"type\": \"Disease\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03744", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Generally, carboplatin is said to have milder side effects than cisplatin, whose ocular and orbital toxicity are well known.", "completion": "{\"entities\": [{\"text\": \"carboplatin\", \"type\": \"Chemical\"}, {\"text\": \"cisplatin\", \"type\": \"Chemical\"}, {\"text\": \"ocular and orbital toxicity\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01660", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 2 %; p =. 0006) but not associated with higher rates of early study withdrawal.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03974", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The aim of the experiment was to evaluate the developmental toxicity of the non - selective (piroxicam) and selective (DFU; 5,5-dimethyl-3-(3-fluorophenyl)-4-(4-methylsulphonyl) phenyl-2(5H)-furanon) COX - 2 inhibitors.", "completion": "{\"entities\": [{\"text\": \"toxicity\", \"type\": \"Disease\"}, {\"text\": \"piroxicam\", \"type\": \"Chemical\"}, {\"text\": \"DFU\", \"type\": \"Chemical\"}, {\"text\": \"5,5-dimethyl-3-(3-fluorophenyl)-4-(4-methylsulphonyl) phenyl-2(5H)-furanon\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03406", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Ototoxicity appeared closely related to a prolonged administration and higher total dose of ototoxic drugs, particularly aminoglycosides and furosemide.", "completion": "{\"entities\": [{\"text\": \"Ototoxicity\", \"type\": \"Disease\"}, {\"text\": \"ototoxic\", \"type\": \"Disease\"}, {\"text\": \"aminoglycosides\", \"type\": \"Chemical\"}, {\"text\": \"furosemide\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03035", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSION: Cocaine use predisposed aneurysmal rupture at a significantly earlier age and in much smaller aneurysms", "completion": "{\"entities\": [{\"text\": \"Cocaine\", \"type\": \"Chemical\"}, {\"text\": \"aneurysmal rupture\", \"type\": \"Disease\"}, {\"text\": \"aneurysms\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01213", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: Twenty - six renal allograft biopsy specimens from 1 9 renal transplant patients who underwent transplantations between 1991 and 1993 were evaluated.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03743", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Therefore, patients with glioblastoma sometimes have intracarotid injection of carcinostatics added to the treatment regimen.", "completion": "{\"entities\": [{\"text\": \"glioblastoma\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01464", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 1; 95% confidence interval [CI] 1.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01062", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Two patients had a cholestatic hepatitis induced by carbimazole (N omercazole ). Two others had a mixed (cholestatic and cytolytic) hepatitis following carbimazole.", "completion": "{\"entities\": [{\"text\": \"cholestatic\", \"type\": \"Disease\"}, {\"text\": \"cholestatic hepatitis\", \"type\": \"Disease\"}, {\"text\": \"hepatitis\", \"type\": \"Disease\"}, {\"text\": \"carbimazole\", \"type\": \"Chemical\"}, {\"text\": \"N omercazole\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-02564", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The present study was performed to elucidate the role of SGK1 in the volume retention and fibrosis during nephrotic syndrome.", "completion": "{\"entities\": [{\"text\": \"volume retention\", \"type\": \"Disease\"}, {\"text\": \"fibrosis\", \"type\": \"Disease\"}, {\"text\": \"nephrotic syndrome\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-reassigned-02303", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Theophylline neurotoxicity in pregnant rats.", "completion": "{\"entities\": [{\"text\": \"Theophylline\", \"type\": \"Chemical\"}, {\"text\": \"neurotoxicity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03131", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The patient was discharged and continued outpatient dialysis for 1 month until his renal function recovered.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04626", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: The son of an 84 - year - old male discovered a newspaper report stating clinical success with plant extracts in Alzheimer's disease.", "completion": "{\"entities\": [{\"text\": \"Alzheimer's disease\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01753", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Mitochondrial radiocalcium uptakes were significantly decreased in animals pretreated with acetylsalicylic acid or dipyridamole or when hydrocortisone was added to the epinephrine infusion (2, 682, 2, 803, and 3, 424 counts per minute per gram of dried fraction, respectively ). Myocardial calcium concentrations also were decreased (11.", "completion": "{\"entities\": [{\"text\": \"radiocalcium\", \"type\": \"Chemical\"}, {\"text\": \"calcium\", \"type\": \"Chemical\"}, {\"text\": \"acetylsalicylic acid\", \"type\": \"Chemical\"}, {\"text\": \"dipyridamole\", \"type\": \"Chemical\"}, {\"text\": \"hydrocortisone\", \"type\": \"Chemical\"}, {\"text\": \"epinephrine\", \"type\": \"Chemical\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-03732", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: One hour after the administration of gamma-HCH, the activity of seizure - inducing agents was increased, regardless of their mechanism, while 24 h after gamma-HCH a differential response was observed.", "completion": "{\"entities\": [{\"text\": \"gamma-HCH\", \"type\": \"Chemical\"}, {\"text\": \"seizure\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00772", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Furthermore, adriamycin induced the formation of autophagic vacuoles, and 3MA strongly downregulated the expression of beclin 1 in adriamycin - induced failing heart and inhibited the formation of autophagic vacuoles.", "completion": "{\"entities\": [{\"text\": \"adriamycin\", \"type\": \"Chemical\"}, {\"text\": \"3MA\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02981", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 72 ). DISCUSSION: Quantifying tremor", "completion": "{\"entities\": [{\"text\": \"tremor\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00142", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The release rate of epinephrine", "completion": "{\"entities\": [{\"text\": \"epinephrine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04703", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Zyban, a sustained - release formulation of bupropion hydrochloride, was recently released in Ireland, as a smoking cessation aid.", "completion": "{\"entities\": [{\"text\": \"Zyban\", \"type\": \"Chemical\"}, {\"text\": \"bupropion hydrochloride\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00863", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The effects of continuous positive airway pressure (CPAP) on cardiovascular dynamics and pulmonary shunt (QS / QT) were investigated in 12 dogs before and during sodium nitroprusside infusion that decreased mean arterial blood pressure 40 - 50 per cent.", "completion": "{\"entities\": [{\"text\": \"sodium nitroprusside\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01518", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Genetic study did not find any mutation in her genes that encode cardiac IKr channel proteins.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01792", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Neuropsychiatric side effects after the use of mefloquine.", "completion": "{\"entities\": [{\"text\": \"mefloquine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03741", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: Glioblastoma is a malignant tumor that occurs in the cerebrum during adulthood.", "completion": "{\"entities\": [{\"text\": \"Glioblastoma\", \"type\": \"Disease\"}, {\"text\": \"malignant tumor\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03409", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 15 cases of cimetidine - associated mental confusion have been reported.", "completion": "{\"entities\": [{\"text\": \"cimetidine\", \"type\": \"Chemical\"}, {\"text\": \"confusion\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03311", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The narrow therapeutic window observed with haloperidol may also apply to other neuroleptics used in Alzheimer's disease patients with psychosis and disruptive behaviors", "completion": "{\"entities\": [{\"text\": \"haloperidol\", \"type\": \"Chemical\"}, {\"text\": \"Alzheimer's disease\", \"type\": \"Disease\"}, {\"text\": \"psychosis\", \"type\": \"Disease\"}, {\"text\": \"disruptive behaviors\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04182", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Nicotine activates the sympathetic nervous system and in this way could contribute to cardiovascular disease.", "completion": "{\"entities\": [{\"text\": \"Nicotine\", \"type\": \"Chemical\"}, {\"text\": \"cardiovascular disease\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03762", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We used an in vitro model of chemotherapy induced peripheral neuropathy that closely mimic the in vivo condition by exposing primary cultures of dorsal root ganglion (DRG) sensory neurons to paclitaxel and cisplatin, two widely used and highly effective chemotherapeutic drugs.", "completion": "{\"entities\": [{\"text\": \"peripheral neuropathy\", \"type\": \"Disease\"}, {\"text\": \"paclitaxel\", \"type\": \"Chemical\"}, {\"text\": \"cisplatin\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01656", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 4 %; p =. 02 ), but no other significant group differences regarding electrocardiogram and other cardiovascular outcomes.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-05131", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Previous studies have demonstrated that Rg1 might be a useful agent for the prevention and treatment of the adverse effects of morphine.", "completion": "{\"entities\": [{\"text\": \"Rg1\", \"type\": \"Chemical\"}, {\"text\": \"morphine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00372", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Both compounds caused deformations and lethality in a dose - dependent manner.", "completion": "{\"entities\": [{\"text\": \"deformations\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00117", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05) increase in heart rate and cardiac output; rebound hypertension was observed in three patients after discontinuation of nitroprusside.", "completion": "{\"entities\": [{\"text\": \"increase in heart rate and cardiac output\", \"type\": \"Disease\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}, {\"text\": \"nitroprusside\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03436", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After EE treatment, changes in immunostaining for 7H6 and ZO - 1 were similar to those seen in periportal hepatocytes after BDL, but distributed more diffusely throughout the lobule.", "completion": "{\"entities\": [{\"text\": \"EE\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01926", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Liver biopsies should be undertaken at regular intervals if azathioprine therapy is continued so that structural liver damage", "completion": "{\"entities\": [{\"text\": \"azathioprine\", \"type\": \"Chemical\"}, {\"text\": \"liver damage\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03961", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thyroid disorders, illicit drug or stimulant use, and acute alcohol intoxication are among these causes.", "completion": "{\"entities\": [{\"text\": \"Thyroid disorders\", \"type\": \"Disease\"}, {\"text\": \"acute alcohol intoxication\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03263", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: l (- 1 )) but this was not statistically significant.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04727", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 mg / kg ip ), a relatively selective inhibitor of inducible NO synthase (L - NIL; 1.", "completion": "{\"entities\": [{\"text\": \"NO\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03929", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Neurologic toxicity was reported in 52% of patients.", "completion": "{\"entities\": [{\"text\": \"Neurologic toxicity\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04297", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Two separate equimolar doses (0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03594", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHOD: FS containing aprotinin or different concentrations of tAMCA (0.", "completion": "{\"entities\": [{\"text\": \"tAMCA\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03007", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Simvastatin - induced bilateral leg compartment syndrome and myonecrosis associated with hypothyroidism.", "completion": "{\"entities\": [{\"text\": \"Simvastatin\", \"type\": \"Chemical\"}, {\"text\": \"compartment syndrome\", \"type\": \"Disease\"}, {\"text\": \"myonecrosis\", \"type\": \"Disease\"}, {\"text\": \"hypothyroidism\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00879", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Removal of the carotid sinuses caused an elevation blood pressure and heart rate and abolished the negative chronotropic effect of norepinephrine.", "completion": "{\"entities\": [{\"text\": \"norepinephrine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00707", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Laryngeal electromyography (thyroarytenoid muscle) showed ample denervation potentials.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04254", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Ventricular tachyarrhythmias during cesarean section after ritodrine therapy: interaction with anesthetics.", "completion": "{\"entities\": [{\"text\": \"Ventricular tachyarrhythmias\", \"type\": \"Disease\"}, {\"text\": \"ritodrine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01224", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: At the highest effective doses, PG-9 did not produce any collateral symptoms as revealed by the Irwin test, and it did not modify spontaneous motility and inspection activity, as revealed by the hole - board test.", "completion": "{\"entities\": [{\"text\": \"PG-9\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00566", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The rate - limiting constituent of collecting duct sodium transport is the epithelial sodium channel (ENaC ). We examined the abundance of ENaC subunit mRNAs and proteins in puromycin aminonucleoside (PAN )- induced nephrotic syndrome.", "completion": "{\"entities\": [{\"text\": \"sodium\", \"type\": \"Chemical\"}, {\"text\": \"puromycin aminonucleoside\", \"type\": \"Chemical\"}, {\"text\": \"PAN\", \"type\": \"Chemical\"}, {\"text\": \"nephrotic syndrome\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00867", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Nitroprusside caused significant decreases in arterial blood pressure and systemic vascular resistance and increases in heart rate, but did not change cardiac output or QS / QT.", "completion": "{\"entities\": [{\"text\": \"Nitroprusside\", \"type\": \"Chemical\"}, {\"text\": \"decreases in arterial blood pressure\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02597", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This study suggests that for healthy older adults who are not suffering from chronic pain, neurocognitive and pharmacodynamic changes in response to a 10 - mg dose of immediate - release oxycodone are similar to those observed for middle - aged adults.", "completion": "{\"entities\": [{\"text\": \"chronic pain\", \"type\": \"Disease\"}, {\"text\": \"oxycodone\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01446", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 2 microg / day, 12 wk) of Ovx rats restored the hemodynamic and locomotor effects of alpha-methyldopa to sham - operated levels.", "completion": "{\"entities\": [{\"text\": \"alpha-methyldopa\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01583", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We investigated the muscle pathology in 8 such cases.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-reassigned-00129", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Median duration of response was 34.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01051", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A second group of rats was treated identically and, in addition, received an infusion of saralasin (a competitive inhibitor of angiotensin II) throughout the experimental period.", "completion": "{\"entities\": [{\"text\": \"saralasin\", \"type\": \"Chemical\"}, {\"text\": \"angiotensin II\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01685", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05) decrease in body weight, endogenous antioxidants, Na +/ K + ATPase and Mg + 2 ATPase levels.", "completion": "{\"entities\": [{\"text\": \"Na\", \"type\": \"Chemical\"}, {\"text\": \"K\", \"type\": \"Chemical\"}, {\"text\": \"Mg\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01737", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This novel model of OCD demonstrates that drug exposure during a sensitive period can program disease - like systems permanently, which could have implications for current and future therapeutic strategies for this and other psychiatric disorders", "completion": "{\"entities\": [{\"text\": \"OCD\", \"type\": \"Disease\"}, {\"text\": \"psychiatric disorders\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01340", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A patient who received antithymocyte globulin therapy for aplastic anemia due to D-penicillamine therapy is described.", "completion": "{\"entities\": [{\"text\": \"antithymocyte globulin\", \"type\": \"Chemical\"}, {\"text\": \"aplastic anemia\", \"type\": \"Disease\"}, {\"text\": \"D-penicillamine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04418", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Additionally, ritonavir treatment selectively increased the relative levels of PPARgamma mRNA, a transcription factor responsible for the regulation of CD36 mRNA expression.", "completion": "{\"entities\": [{\"text\": \"ritonavir\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04723", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The two hypotensive patients required treatment for shock.", "completion": "{\"entities\": [{\"text\": \"hypotensive\", \"type\": \"Disease\"}, {\"text\": \"shock\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00338", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 mg / kg) and 24 hour urine samples were obtained prior to sacrifice on days 3, 5, 7, 10, 17, 27, 41 (N = 5 - 10 per group ). The kidneys were removed, flushed with ice cold TRIS buffer.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00221", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Our case supports the hypothesis that endogenous renal prostaglandins play a role in the maintenance of renal blood flow when circulating plasma volume is diminished.", "completion": "{\"entities\": [{\"text\": \"prostaglandins\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00961", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Among these 47 patients the mean (+/- SD) age was 32.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04425", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, one drawback of such studies in genetically deficient rats is the fact that compensatory changes with upregulation of other transporters can occur.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00641", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Sirolimus (SRL) is a new, potent immunosuppressive agent.", "completion": "{\"entities\": [{\"text\": \"Sirolimus\", \"type\": \"Chemical\"}, {\"text\": \"SRL\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01733", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: g ., win - shift paradigm ), hoarding, and corticostriatal dysfunction.", "completion": "{\"entities\": [{\"text\": \"hoarding\", \"type\": \"Disease\"}, {\"text\": \"corticostriatal dysfunction\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04612", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 01 ). End - systolic left ventricular posterior wall dimension at the 5 - micrograms / kg per min dobutamine infusion for the doxorubicin", "completion": "{\"entities\": [{\"text\": \"dobutamine\", \"type\": \"Chemical\"}, {\"text\": \"doxorubicin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03152", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: The objective of this study was to determine the feasibility, response rate, and toxicity of a paclitaxel, cisplatin, and gemcitabine combination to treat metastatic NSCLC.", "completion": "{\"entities\": [{\"text\": \"toxicity\", \"type\": \"Disease\"}, {\"text\": \"paclitaxel\", \"type\": \"Chemical\"}, {\"text\": \"cisplatin\", \"type\": \"Chemical\"}, {\"text\": \"gemcitabine\", \"type\": \"Chemical\"}, {\"text\": \"NSCLC\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-04637", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, increased dyspnoea and bronchospasm necessitated reintubation.", "completion": "{\"entities\": [{\"text\": \"dyspnoea\", \"type\": \"Disease\"}, {\"text\": \"bronchospasm\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01055", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This study indicates that with stable halothane anesthesia, the partial recovery of blood pressure during SNP infusion and the post - SNP rebound of blood pressure can be completely blocked by saralasin.", "completion": "{\"entities\": [{\"text\": \"halothane\", \"type\": \"Chemical\"}, {\"text\": \"SNP\", \"type\": \"Chemical\"}, {\"text\": \"saralasin\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03328", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05 ), interstitial macrophage influx (r = 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03293", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The rat biodistribution studies showed a rapid blood clearance via the kidneys.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04955", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 38 %). Bromocriptine was definitely effective in cases with prolactin greater than 35 ng ./ ml .(8 of 12 compared to only 9 of 22 cases with prolactin between 20 and 35 ng ./ ml .). Testosterone was low in less than 50% of cases with prolactin greater than 35 ng ./ ml.", "completion": "{\"entities\": [{\"text\": \"Bromocriptine\", \"type\": \"Chemical\"}, {\"text\": \"Testosterone\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00873", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: L-Dopa (5 mg / kg i.", "completion": "{\"entities\": [{\"text\": \"L-Dopa\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00161", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: By contrast, we were unable to substantiate an increased risk from paracetamol consumption for renal papillary necrosis or any of these cancers although there was a suggestion of an association with cancer of the ureter", "completion": "{\"entities\": [{\"text\": \"paracetamol\", \"type\": \"Chemical\"}, {\"text\": \"renal papillary necrosis\", \"type\": \"Disease\"}, {\"text\": \"cancers\", \"type\": \"Disease\"}, {\"text\": \"cancer of the ureter\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03712", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Twenty - six had minimal prior therapy (good risk ), 23 had extensive prior therapy (poor risk ), and six had renal and/or hepatic dysfunction.", "completion": "{\"entities\": [{\"text\": \"renal and/or hepatic dysfunction\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01846", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Tolerance and antiviral effect of ribavirin in patients with Argentine hemorrhagic fever.", "completion": "{\"entities\": [{\"text\": \"ribavirin\", \"type\": \"Chemical\"}, {\"text\": \"Argentine hemorrhagic fever\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01152", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After MTX administration a significant increase (p = 0.", "completion": "{\"entities\": [{\"text\": \"MTX\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03881", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Catalepsy was induced by haloperidol (2 mg / kg p.", "completion": "{\"entities\": [{\"text\": \"Catalepsy\", \"type\": \"Disease\"}, {\"text\": \"haloperidol\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04004", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The aim of this study was to examine further the renal function, including morphological analysis of the kidneys of male Sprague - Dawley rats treated with either cyclosporine A (CsA ), tacrolimus (FK506) or SRL as monotherapies or in different combinations.", "completion": "{\"entities\": [{\"text\": \"cyclosporine A\", \"type\": \"Chemical\"}, {\"text\": \"CsA\", \"type\": \"Chemical\"}, {\"text\": \"tacrolimus\", \"type\": \"Chemical\"}, {\"text\": \"FK506\", \"type\": \"Chemical\"}, {\"text\": \"SRL\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-00882", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: v .) decreased blood pressure and heart rate and decreased the reflex bradycardia to norepinephrine.", "completion": "{\"entities\": [{\"text\": \"bradycardia\", \"type\": \"Disease\"}, {\"text\": \"norepinephrine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03569", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Incorrect diagnosis of the syndrome will lead to a significant reduction of life quality in patients suffering from CIPS", "completion": "{\"entities\": [{\"text\": \"CIPS\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02364", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: All patients with a diagnosed cerebral haemorrhage at three hospitals during the period 2000 - 2002 were identified.", "completion": "{\"entities\": [{\"text\": \"cerebral haemorrhage\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00800", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Unexpectedly high concentrations of argatroban were measured in these samples (range, 0 - 32 microg / mL ), and a prolonged plasma argatroban half life (t (1 / 2 )) of 514 minutes was observed (published elimination t (1 / 2) is 39 - 51 minutes [< or = 181 minutes with hepatic impairment ]). CONCLUSIONS: Correlation of plasma argatroban concentration versus the patient' s coagulation variables and clinical course suggest that prolonged elevated levels of plasma argatroban may have contributed to the patient' s extended coagulopathy.", "completion": "{\"entities\": [{\"text\": \"argatroban\", \"type\": \"Chemical\"}, {\"text\": \"hepatic impairment\", \"type\": \"Disease\"}, {\"text\": \"coagulopathy\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01207", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After intravenous administration of labetalol, metoprolol and midazolam the patient' s condition improved, and 15 min later he woke up.", "completion": "{\"entities\": [{\"text\": \"labetalol\", \"type\": \"Chemical\"}, {\"text\": \"metoprolol\", \"type\": \"Chemical\"}, {\"text\": \"midazolam\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02176", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Lidocaine reduced the area of punctate - evoked hyperalgesia significantly.", "completion": "{\"entities\": [{\"text\": \"Lidocaine\", \"type\": \"Chemical\"}, {\"text\": \"hyperalgesia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01219", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the mouse passive - avoidance test, PG-9 (10 - 30 mg / kg, i.", "completion": "{\"entities\": [{\"text\": \"PG-9\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00880", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, L-dopa restored the bradycardia caused by norepinephrine in addition to decreasing blood pressure and heart rate.", "completion": "{\"entities\": [{\"text\": \"L-dopa\", \"type\": \"Chemical\"}, {\"text\": \"bradycardia\", \"type\": \"Disease\"}, {\"text\": \"norepinephrine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01787", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The stimulant action of nicotine was blocked by the central nicotinic antagonist mecamylamine but not by the peripheral nicotinic blocker hexamethonium, indicating that the response is probably mediated by central nicotinic receptors.", "completion": "{\"entities\": [{\"text\": \"nicotine\", \"type\": \"Chemical\"}, {\"text\": \"mecamylamine\", \"type\": \"Chemical\"}, {\"text\": \"hexamethonium\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01994", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHOD: In London and Toronto 154 patients who met DSM - III criteria for panic disorder with agoraphobia were randomised to alprazolam or placebo.", "completion": "{\"entities\": [{\"text\": \"panic disorder\", \"type\": \"Disease\"}, {\"text\": \"agoraphobia\", \"type\": \"Disease\"}, {\"text\": \"alprazolam\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01788", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Nicotine - induced hyperactivity was blocked by the selective D1 antagonist SCH 23390, the selective D2 antagonist raclopride and the D1 / D2 antagonist fluphenazine.", "completion": "{\"entities\": [{\"text\": \"Nicotine\", \"type\": \"Chemical\"}, {\"text\": \"hyperactivity\", \"type\": \"Disease\"}, {\"text\": \"SCH 23390\", \"type\": \"Chemical\"}, {\"text\": \"raclopride\", \"type\": \"Chemical\"}, {\"text\": \"fluphenazine\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-02900", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Ranitidine - induced acute interstitial nephritis in a cadaveric renal allograft.", "completion": "{\"entities\": [{\"text\": \"Ranitidine\", \"type\": \"Chemical\"}, {\"text\": \"interstitial nephritis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02907", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cardiomyopathy is frequent when the total dose exceeds 600 mg / m2 and occurs within one to six months after cessation of therapy.", "completion": "{\"entities\": [{\"text\": \"Cardiomyopathy\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01654", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: There were more incidents of bradycardia in subjects treated with clonidine compared with those not treated with clonidine (17.", "completion": "{\"entities\": [{\"text\": \"bradycardia\", \"type\": \"Disease\"}, {\"text\": \"clonidine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03193", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The antiarrhythmic effects of the sustained release form of mexiletine (Mexitil-Perlongets) were evaluated in a double - blind placebo trial in 630 patients with recent documented myocardial infarction.", "completion": "{\"entities\": [{\"text\": \"mexiletine\", \"type\": \"Chemical\"}, {\"text\": \"Mexitil-Perlongets\", \"type\": \"Chemical\"}, {\"text\": \"myocardial infarction\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02118", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Hemolysis of human erythrocytes induced by tamoxifen is related to disruption of membrane structure.", "completion": "{\"entities\": [{\"text\": \"Hemolysis\", \"type\": \"Disease\"}, {\"text\": \"tamoxifen\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01241", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Over the period 1993 - 1996, 551 cases of VTE were identified in Germany and the UK along with 2066 controls.", "completion": "{\"entities\": [{\"text\": \"VTE\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01977", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The yield of severe cirrhosis of the liver (defined as a shrunken finely nodular liver with micronodular histology, ascites greater than 30 ml, plasma albumin less than 2.", "completion": "{\"entities\": [{\"text\": \"cirrhosis of the liver\", \"type\": \"Disease\"}, {\"text\": \"ascites\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04850", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pyrrolidine dithiocarbamate protects the piriform cortex in the pilocarpine status epilepticus model.", "completion": "{\"entities\": [{\"text\": \"Pyrrolidine dithiocarbamate\", \"type\": \"Chemical\"}, {\"text\": \"pilocarpine\", \"type\": \"Chemical\"}, {\"text\": \"status epilepticus\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-05004", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 to 75 mg / kg IP ). The frequency of sound - induced seizures after 12.", "completion": "{\"entities\": [{\"text\": \"seizures\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01878", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These observations suggest that rigidity should be prevented when alfentanil", "completion": "{\"entities\": [{\"text\": \"rigidity\", \"type\": \"Disease\"}, {\"text\": \"alfentanil\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01461", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Outcomes included venous thromboembolism, cataracts, gallbladder disease, and endometrial hyperplasia or cancer.", "completion": "{\"entities\": [{\"text\": \"venous thromboembolism\", \"type\": \"Disease\"}, {\"text\": \"cataracts\", \"type\": \"Disease\"}, {\"text\": \"gallbladder disease\", \"type\": \"Disease\"}, {\"text\": \"endometrial hyperplasia or cancer\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04848", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These results show that curcumin has beneficial effect in mitigating the deterioration of cognitive functions and oxidative damage in rats treated with phenobarbitone and carbamazepine without significantly altering their serum concentrations.", "completion": "{\"entities\": [{\"text\": \"curcumin\", \"type\": \"Chemical\"}, {\"text\": \"deterioration of cognitive functions\", \"type\": \"Disease\"}, {\"text\": \"phenobarbitone\", \"type\": \"Chemical\"}, {\"text\": \"carbamazepine\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03812", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These findings suggest that NRA0160", "completion": "{\"entities\": [{\"text\": \"NRA0160\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03460", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Patients who received enalapril experienced clinically and statistically significantly less symptomatic hypotension (5.", "completion": "{\"entities\": [{\"text\": \"enalapril\", \"type\": \"Chemical\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00212", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We propose that amphotericin, in the setting of reduced effective arterial volume, may activate tubuloglomerular feedback, thereby contributing to acute renal failure", "completion": "{\"entities\": [{\"text\": \"amphotericin\", \"type\": \"Chemical\"}, {\"text\": \"acute renal failure\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04021", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The hematoma was assessed in vivo by magnetic resonance imaging.", "completion": "{\"entities\": [{\"text\": \"hematoma\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04856", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Low - dose PDTC treatment almost completely protected from lesions in the piriform cortex.", "completion": "{\"entities\": [{\"text\": \"PDTC\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01819", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The effect of mazindol on GH secretion was estimated indirectly by comparing the postabsorptive IGF - I levels obtained following 3, 6, 9, and 12 months in the mazindol treated to those in the placebo groups.", "completion": "{\"entities\": [{\"text\": \"mazindol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05134", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Spatial learning capacity was assessed in the Morris water maze.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04685", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Histologic examination of the renal tissue showed evidence of intravascular coagulation, primarily affecting the small arteries, arterioles, and glomeruli.", "completion": "{\"entities\": [{\"text\": \"intravascular coagulation\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01117", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Reports of persistent paralysis after the discontinuance of these drugs have most often involved aminosteroid - based NMBAs such as vecuronium bromide, especially when used in conjunction with corticosteroids.", "completion": "{\"entities\": [{\"text\": \"paralysis\", \"type\": \"Disease\"}, {\"text\": \"vecuronium bromide\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04581", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The biochemical results of brain biogenic amines of BALB / C mouse strain suggest a probable decrease of catecholamine turnover rate and / or metabolism by monoamine oxidase and a resulting increase in O - methylation of norepinephrine which may account for a behavioral depression caused by amantadine", "completion": "{\"entities\": [{\"text\": \"amines\", \"type\": \"Chemical\"}, {\"text\": \"catecholamine\", \"type\": \"Chemical\"}, {\"text\": \"norepinephrine\", \"type\": \"Chemical\"}, {\"text\": \"behavioral depression\", \"type\": \"Disease\"}, {\"text\": \"amantadine\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-00951", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The typical fluoxetine - induced symptoms of restlessness, constant pacing, purposeless movements of the feet and legs, and marked anxiety were indistinguishable from those of neuroleptic - induced akathisia.", "completion": "{\"entities\": [{\"text\": \"fluoxetine\", \"type\": \"Chemical\"}, {\"text\": \"anxiety\", \"type\": \"Disease\"}, {\"text\": \"akathisia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04574", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Subsequent amantadine treatments produced enhancement of motility from corresponding control in all mouse strains with the BALB / C mice being the least sensitive.", "completion": "{\"entities\": [{\"text\": \"amantadine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02220", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We report a favorable response to treatment with citalopram by a 15 - year - old boy with major depression who exhibited palpebral twitching during his first 2 weeks of treatment.", "completion": "{\"entities\": [{\"text\": \"citalopram\", \"type\": \"Chemical\"}, {\"text\": \"major depression\", \"type\": \"Disease\"}, {\"text\": \"palpebral twitching\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03272", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Male SD rats (n = 30) were treated with Ato (50 mg / kg per day in drinking water) or tap water for 15 days.", "completion": "{\"entities\": [{\"text\": \"Ato\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02963", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Subjects were asked to aim at the centre of a target, subdivided in concentric circles, from 5 m distance.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02610", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Progressive abstinence from cocaine was associated with worsening of all measured polysomnographic sleep outcomes.", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00105", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Our findings show that long - term treatment with high doses of ketoconazole may induce enzyme blockade leading to mineralocorticoid - related hypertension", "completion": "{\"entities\": [{\"text\": \"ketoconazole\", \"type\": \"Chemical\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02074", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 %. Patients given prilocaine were more likely to develop hearing loss (10 out of 22) than those given bupivacaine (4 out of 22 )(P < 0.", "completion": "{\"entities\": [{\"text\": \"prilocaine\", \"type\": \"Chemical\"}, {\"text\": \"hearing loss\", \"type\": \"Disease\"}, {\"text\": \"bupivacaine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01426", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 mg / kg BW ), A (1 )- adenosine receptor agonist N(6)-cyclopentyl adenosine (CPA )(2.", "completion": "{\"entities\": [{\"text\": \"adenosine\", \"type\": \"Chemical\"}, {\"text\": \"N(6)-cyclopentyl adenosine\", \"type\": \"Chemical\"}, {\"text\": \"CPA\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01783", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In addition, the role of dopamine receptors in mediating nicotine - induced locomotor stimulation was investigated by examining the effects of selective D1 and D2 dopamine receptor antagonists on activity induced by nicotine.", "completion": "{\"entities\": [{\"text\": \"dopamine\", \"type\": \"Chemical\"}, {\"text\": \"nicotine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00323", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Age - dependent sensitivity of the rat to neurotoxic effects of streptomycin.", "completion": "{\"entities\": [{\"text\": \"neurotoxic\", \"type\": \"Disease\"}, {\"text\": \"streptomycin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00208", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In a 37 - year - old woman with documented pentazocine - induced fibrous myopathy of triceps and deltoid muscles bilaterally and a three - week history of right wrist drop, electrodiagnostic examination showed a severe but partial lesion of the right radial nerve distal to the branches to the triceps, in addition to the fibrous myopathy", "completion": "{\"entities\": [{\"text\": \"pentazocine\", \"type\": \"Chemical\"}, {\"text\": \"fibrous myopathy\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01181", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Median survival was 16 months.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02371", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 01 ). A warfarin - drug interaction could have contributed to the haemorrhage in 24 (41 %) of the warfarin patients and in 7 of these (12 %) the bleeding complication was considered being possible to avoid.", "completion": "{\"entities\": [{\"text\": \"warfarin\", \"type\": \"Chemical\"}, {\"text\": \"haemorrhage\", \"type\": \"Disease\"}, {\"text\": \"bleeding\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00271", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In a 6 - week double - blind parallel treatment study, dothiepin and amitriptyline were compared to placebo in the treatment of 33 depressed outpatients.", "completion": "{\"entities\": [{\"text\": \"dothiepin\", \"type\": \"Chemical\"}, {\"text\": \"amitriptyline\", \"type\": \"Chemical\"}, {\"text\": \"depressed\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03864", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 035 ), respectively, while nausea in the first 24 h was decreased from 42% to 27 %(P = 0.", "completion": "{\"entities\": [{\"text\": \"nausea\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01761", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Changes in depressive status associated with topical beta - blockers.", "completion": "{\"entities\": [{\"text\": \"depressive\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00989", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 02 ). It is concluded that increases in the SPV and the delta down are characteristic of a hypotensive state due to a predominant decrease in preload.", "completion": "{\"entities\": [{\"text\": \"hypotensive\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02918", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Evidence is accumulating that lindane can be toxic to the central nervous system and may be associated with aplastic anaemia.", "completion": "{\"entities\": [{\"text\": \"lindane\", \"type\": \"Chemical\"}, {\"text\": \"toxic to the central nervous system\", \"type\": \"Disease\"}, {\"text\": \"aplastic anaemia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04812", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the antinociceptive and antiamnesic dose range ,(+/-)- PG-9", "completion": "{\"entities\": [{\"text\": \"PG-9\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04379", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We report that prenatally protein deprived (PD) female rats showed an increased stereotypic response to apomorphine and an increased locomotor response to amphetamine in adulthood.", "completion": "{\"entities\": [{\"text\": \"apomorphine\", \"type\": \"Chemical\"}, {\"text\": \"amphetamine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03995", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The present study was designed to evaluate two endogenous and one synthetic neuroactive steroid that positively modulate the gamma-aminobutyric acid (GABA (A )) receptor against the increase in sensitivity to the convulsant effects of cocaine engendered by repeated cocaine administration (seizure kindling ). Allopregnanolone (3alpha-hydroxy-5alpha-pregnan-20-one ), pregnanolone (3alpha-hydroxy-5beta-pregnan-20-one) and ganaxolone (a synthetic derivative of allopregnanolone 3alpha-hydroxy-3beta-methyl-5alpha-pregnan-20-one) were tested for their ability to suppress the expression (anticonvulsant effect) and development (antiepileptogenic effect) of cocaine - kindled seizures in male, Swiss - Webster mice.", "completion": "{\"entities\": [{\"text\": \"steroid\", \"type\": \"Chemical\"}, {\"text\": \"gamma-aminobutyric acid\", \"type\": \"Chemical\"}, {\"text\": \"GABA\", \"type\": \"Chemical\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"seizure\", \"type\": \"Disease\"}, {\"text\": \"Allopregnanolone\", \"type\": \"Chemical\"}, {\"text\": \"pregnanolone\", \"type\": \"Chemical\"}, {\"text\": \"3alpha-hydroxy-5alpha-pregnan-20-one\", \"type\": \"Chemical\"}, {\"text\": \"3alpha-hydroxy-5beta-pregnan-20-one\", \"type\": \"Chemical\"}, {\"text\": \"ganaxolone\", \"type\": \"Chemical\"}, {\"text\": \"allopregnanolone\", \"type\": \"Chemical\"}, {\"text\": \"3alpha-hydroxy-3beta-methyl-5alpha-pregnan-20-one\", \"type\": \"Chemical\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}]}", "n_entities": 13}
{"ref": "bc5cdr-train-03119", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The emergency nurse ought to be familiar with some of the cardiovascular consequences of cocaine use.", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01160", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Our studies indicate that nephrotoxicity of MTX + 5-FU + CY", "completion": "{\"entities\": [{\"text\": \"nephrotoxicity\", \"type\": \"Disease\"}, {\"text\": \"MTX\", \"type\": \"Chemical\"}, {\"text\": \"5-FU\", \"type\": \"Chemical\"}, {\"text\": \"CY\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04519", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Octreotide - induced hypoxemia and pulmonary hypertension in premature neonates.", "completion": "{\"entities\": [{\"text\": \"Octreotide\", \"type\": \"Chemical\"}, {\"text\": \"hypoxemia\", \"type\": \"Disease\"}, {\"text\": \"pulmonary hypertension\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04352", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This pilot trial aimed to evaluate the role of glutamate supplementation for preventing PAC - induced peripheral neuropathy in a randomized, placebo - controlled, double - blinded clinical and electro - diagnostic study.", "completion": "{\"entities\": [{\"text\": \"glutamate\", \"type\": \"Chemical\"}, {\"text\": \"PAC\", \"type\": \"Chemical\"}, {\"text\": \"peripheral neuropathy\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02243", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These findings show a significant interaction between morphine and metamizol in chronically treated rats, suggesting that this combination could be useful for the treatment of chronic pain", "completion": "{\"entities\": [{\"text\": \"morphine\", \"type\": \"Chemical\"}, {\"text\": \"metamizol\", \"type\": \"Chemical\"}, {\"text\": \"chronic pain\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-reassigned-00006", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The implications of using famotidine", "completion": "{\"entities\": [{\"text\": \"famotidine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03729", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Differential effects of gamma-hexachlorocyclohexane (lindane) on pharmacologically - induced seizures.", "completion": "{\"entities\": [{\"text\": \"gamma-hexachlorocyclohexane\", \"type\": \"Chemical\"}, {\"text\": \"lindane\", \"type\": \"Chemical\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03815", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Jaundice occurred after administration of troleandomycin for 7 days and was associated with hypereosinophilia.", "completion": "{\"entities\": [{\"text\": \"Jaundice\", \"type\": \"Disease\"}, {\"text\": \"troleandomycin\", \"type\": \"Chemical\"}, {\"text\": \"hypereosinophilia\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04227", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The 65 dogs in the study received injections in the subarachnoid space as follows: 6 to 8 ml of bupivacaine (N = 15 ), 2-chloroprocaine-CE (N = 20 ), low pH normal saline (pH 3.", "completion": "{\"entities\": [{\"text\": \"bupivacaine\", \"type\": \"Chemical\"}, {\"text\": \"2-chloroprocaine-CE\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00601", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the present study, we tested the effects of i.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01534", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: o .) reduced significantly the brain acetylcholinesterase activity and cholesterol levels in young and aged mice.", "completion": "{\"entities\": [{\"text\": \"cholesterol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00850", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Previous studies have indicated that the globus pallidus receives neurotensinergic innervation from the striatum, and systemic administration of a neurotensin analog could produce antiparkinsonian effects.", "completion": "{\"entities\": [{\"text\": \"neurotensin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-reassigned-00597", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 001) Dex - induced hypertension.", "completion": "{\"entities\": [{\"text\": \"Dex\", \"type\": \"Chemical\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01110", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RAST was positive for AX in 22 patients (41 %) and to BPO in just 5 (9 %). of the sera with negative RAST for AX were positive to BPO.", "completion": "{\"entities\": [{\"text\": \"AX\", \"type\": \"Chemical\"}, {\"text\": \"BPO\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03694", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Preliminary results of an Eastern Cooperative Oncology Group study of single - agent paclitaxel (Taxol; Bristol - Myers Squibb Company, Princeton, NJ) reported a 37% response rate in patients with head and neck cancer, and the paclitaxel / cisplatin combination has been used successfully and has significantly improved median response duration in ovarian cancer patients.", "completion": "{\"entities\": [{\"text\": \"paclitaxel\", \"type\": \"Chemical\"}, {\"text\": \"Taxol\", \"type\": \"Chemical\"}, {\"text\": \"head and neck cancer\", \"type\": \"Disease\"}, {\"text\": \"cisplatin\", \"type\": \"Chemical\"}, {\"text\": \"ovarian cancer\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-04733", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It was also shown that both products of inducible NO synthase and neuronal NO synthase activation as well as bradykinin are involved in hyperalgesia produced by vincristine.", "completion": "{\"entities\": [{\"text\": \"NO\", \"type\": \"Chemical\"}, {\"text\": \"bradykinin\", \"type\": \"Chemical\"}, {\"text\": \"hyperalgesia\", \"type\": \"Disease\"}, {\"text\": \"vincristine\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00408", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Differences in the labelling pattern occurred with different antibodies which apparently depended on molecular weight class of NFs and phosphorylation state.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04938", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: PURPOSE: We reviewed the results of serum testosterone and prolactin determination in 1, 022 patients referred because of erectile dysfunction and compared the data with history, results of physical examination, other etiological investigations and effects of endocrine therapy to refine the rules of cost - effective endocrine screening and to pinpoint actual responsibility for hormonal abnormalities.", "completion": "{\"entities\": [{\"text\": \"testosterone\", \"type\": \"Chemical\"}, {\"text\": \"erectile dysfunction\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00258", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The anatomical and aetiological diagnoses of peripheral nerve disease excluding its primary benign and malignant disorders, as seen in 358 Nigerians are presented.", "completion": "{\"entities\": [{\"text\": \"peripheral nerve disease\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03470", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Interactive effects of variations in [Na] o and [Ca] o on rat atrial spontaneous frequency.", "completion": "{\"entities\": [{\"text\": \"Na\", \"type\": \"Chemical\"}, {\"text\": \"Ca\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00048", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The disease activity was primarily measured by a modified individual grading score.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04616", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The effects of aminophylline on the ventricular fibrillation threshold during normal acid - base conditions and during respiratory failure were studied in anesthetized open chest dogs.", "completion": "{\"entities\": [{\"text\": \"aminophylline\", \"type\": \"Chemical\"}, {\"text\": \"ventricular fibrillation\", \"type\": \"Disease\"}, {\"text\": \"respiratory failure\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01046", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The similarity between the histologic appearances of busulfan cystitis and both radiation and cyclophosphamide - induced cystitis is discussed and the world literature reviewed.", "completion": "{\"entities\": [{\"text\": \"busulfan\", \"type\": \"Chemical\"}, {\"text\": \"cystitis\", \"type\": \"Disease\"}, {\"text\": \"cyclophosphamide\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04915", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Our aim was to characterize both lines' sensitivities to various physiological effects of other ligands of the GABA (A) receptor.", "completion": "{\"entities\": [{\"text\": \"GABA\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03788", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A pyridoxine - dependent behavioral disorder unmasked by isoniazid.", "completion": "{\"entities\": [{\"text\": \"pyridoxine\", \"type\": \"Chemical\"}, {\"text\": \"behavioral disorder\", \"type\": \"Disease\"}, {\"text\": \"isoniazid\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01849", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The average time of death was delayed.", "completion": "{\"entities\": [{\"text\": \"death\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04563", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Desipramine - induced delirium at\" subtherapeutic\" concentrations: a case report.", "completion": "{\"entities\": [{\"text\": \"Desipramine\", \"type\": \"Chemical\"}, {\"text\": \"delirium\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02502", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: TAC has been shown to be a potent immunosuppressive agent for solid organ transplantation in pediatrics.", "completion": "{\"entities\": [{\"text\": \"TAC\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04806", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Based on these data, it can be postulated that (+/-)- PG-9 exerted an antinociceptive effect mediated by a central potentiation of cholinergic transmission .(+/-)- PG-9 (10 - 40 mg kg - 1 i.", "completion": "{\"entities\": [{\"text\": \"PG-9\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01286", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The three compounds vary in their affinities for sigma2 receptors and exhibit negligible affinities for dopamine, opioid, GABA (A) and NMDA receptors.", "completion": "{\"entities\": [{\"text\": \"dopamine\", \"type\": \"Chemical\"}, {\"text\": \"GABA\", \"type\": \"Chemical\"}, {\"text\": \"NMDA\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02809", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 1 minutes and 60 +/- 9 %, respectively.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01910", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The most frequently observed side effect was fecal occult blood (25% of patients ); however, there was no other evidence of gastrointestinal (GI) bleeding in these patients.", "completion": "{\"entities\": [{\"text\": \"fecal occult blood\", \"type\": \"Disease\"}, {\"text\": \"gastrointestinal (GI) bleeding\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03506", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: infusion of morphine (mean 73.", "completion": "{\"entities\": [{\"text\": \"morphine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02873", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, comparison with the baseline showed small but significant reduction in dyskinesia severity following real rTMS but not placebo.", "completion": "{\"entities\": [{\"text\": \"dyskinesia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02339", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The second episode was more severe than the first; and although both were treated with intensive corticosteroid therapy, renal function remained impaired.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04718", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: For three patients, the decision was made not to proceed with angiography after positive preangiographic testing.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04790", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Different mechanisms have been suggested for cocaine toxicity including an increase in oxidative stress but the association between oxidative status in the brain and cocaine induced - behaviour is poorly understood.", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01511", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 05 ). A significant correlation was found between baseline TAFI antigen concentrations and the duration of amenorrhea (P < 0.", "completion": "{\"entities\": [{\"text\": \"amenorrhea\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02664", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Glucocorticoid - induced hypertension (GC - HT) in the rat is associated with nitric oxide - redox imbalance.", "completion": "{\"entities\": [{\"text\": \"hypertension\", \"type\": \"Disease\"}, {\"text\": \"HT\", \"type\": \"Disease\"}, {\"text\": \"nitric oxide\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04826", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A total of sixty patients were trated with bromperidol first in open conditions (20 patients ), then on a double blind basis (40 patients) with haloperidol as the reference substance.", "completion": "{\"entities\": [{\"text\": \"bromperidol\", \"type\": \"Chemical\"}, {\"text\": \"haloperidol\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04042", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Hepatitis was usually reversible when treatment was stopped, with the results of liver function tests returning to normal after an average of 3.", "completion": "{\"entities\": [{\"text\": \"Hepatitis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02025", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After withdrawal of octreotide in 10 patients without gallstones, 8 patients assessed had return of normal gallbladder contractility within 1 month.", "completion": "{\"entities\": [{\"text\": \"octreotide\", \"type\": \"Chemical\"}, {\"text\": \"gallstones\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00782", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 7 %). It was\" serious\" for almost 2 / 3 of the patients (62.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04516", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The remaining 1 patient (20.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04049", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Haemodilution in groups B and C was produced by withdrawing approximately 1000 mL of blood and replacing it with the same amount of dextran solution, and final haematocrit values were 21 or 22 %. Controlled hypotension in groups A and C was induced with PGE1 to maintain mean arterial blood pressure at 55 mmHg for 180 min.", "completion": "{\"entities\": [{\"text\": \"Haemodilution\", \"type\": \"Disease\"}, {\"text\": \"dextran\", \"type\": \"Chemical\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}, {\"text\": \"PGE1\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04751", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Vigabatrin was also used in the treatment of two children.", "completion": "{\"entities\": [{\"text\": \"Vigabatrin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04737", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Therefore, concomitant administration of small doses of bradykinin receptor antagonists and NO synthase inhibitors can be effective in alleviation of neuropathic pain", "completion": "{\"entities\": [{\"text\": \"bradykinin\", \"type\": \"Chemical\"}, {\"text\": \"NO\", \"type\": \"Chemical\"}, {\"text\": \"neuropathic pain\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01357", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Prenatal dexamethasone programs hypertension and renal injury in the rat.", "completion": "{\"entities\": [{\"text\": \"dexamethasone\", \"type\": \"Chemical\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}, {\"text\": \"renal injury\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04330", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 001) for 30 minutes, increased left ventricular filling pressure to 17 +/- 2 mm Hg (P less than 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01280", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: We conclude that in transplants, there is a strong association between well - developed PTCR and TG, while the significance of mild PTCR and its predictive value in the absence of TG is unclear.", "completion": "{\"entities\": [{\"text\": \"TG\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03077", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Remission induction of meningeal leukemia with high - dose intravenous methotrexate.", "completion": "{\"entities\": [{\"text\": \"meningeal leukemia\", \"type\": \"Disease\"}, {\"text\": \"methotrexate\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04891", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 6 ). Serious adverse events were reported in 11 and 13 patients in the respective groups.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01586", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Progressive improvement occurred in 7 cases after commencement of prednisolone and methotrexate, and in one case spontaneously.", "completion": "{\"entities\": [{\"text\": \"prednisolone\", \"type\": \"Chemical\"}, {\"text\": \"methotrexate\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05211", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Treatment for ticlopidine - induced aplastic anemia with colony - stimulating factors seemed to have little effect.", "completion": "{\"entities\": [{\"text\": \"ticlopidine\", \"type\": \"Chemical\"}, {\"text\": \"aplastic anemia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03950", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The present study sought to characterize the cognitive - enhancing effects of the 5-HT (6) antagonist Ro4368554 (3-benzenesulfonyl-7-(4-methyl-piperazin-1-yl)1H-indole) in a rat object recognition task employing a cholinergic (scopolamine pretreatment) and a serotonergic -(tryptophan (TRP) depletion) deficient model, and compared its pattern of action with that of the acetylcholinesterase inhibitor metrifonate.", "completion": "{\"entities\": [{\"text\": \"5-HT\", \"type\": \"Chemical\"}, {\"text\": \"Ro4368554\", \"type\": \"Chemical\"}, {\"text\": \"3-benzenesulfonyl-7-(4-methyl-piperazin-1-yl)1H-indole\", \"type\": \"Chemical\"}, {\"text\": \"scopolamine\", \"type\": \"Chemical\"}, {\"text\": \"tryptophan\", \"type\": \"Chemical\"}, {\"text\": \"TRP\", \"type\": \"Chemical\"}, {\"text\": \"metrifonate\", \"type\": \"Chemical\"}]}", "n_entities": 7}
{"ref": "bc5cdr-train-00584", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 001 ). However, plasma CGRP concentrations failed to change during immediate headache and in the subjects with no migraine attack.", "completion": "{\"entities\": [{\"text\": \"CGRP\", \"type\": \"Chemical\"}, {\"text\": \"headache\", \"type\": \"Disease\"}, {\"text\": \"migraine\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01995", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Subjects in each drug group also received either exposure or relaxation.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00263", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 1 %) and presented mainly as sensory and sensori-motor neuropathy.", "completion": "{\"entities\": [{\"text\": \"sensori-motor neuropathy\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04469", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the current study, the frequency of thrombotic microangiopathy", "completion": "{\"entities\": [{\"text\": \"thrombotic microangiopathy\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05113", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Hepatitis B virus (HBV) is one of the major causes of chronic liver disease worldwide.", "completion": "{\"entities\": [{\"text\": \"Hepatitis B\", \"type\": \"Disease\"}, {\"text\": \"liver disease\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-01054", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Patients were randomized to receive 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03140", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: PATIENTS AND METHODS: Forty - six eligible patients with measurable lesions were included and were stratified according to previous chemotherapy.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04055", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Levodopa is the most effective drug for the treatment of Parkinson's disease.", "completion": "{\"entities\": [{\"text\": \"Levodopa\", \"type\": \"Chemical\"}, {\"text\": \"Parkinson's disease\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00336", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The temporal relationship between lipid peroxidation in the kidney and proteinuria was examined in this study.", "completion": "{\"entities\": [{\"text\": \"proteinuria\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00756", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After gastric surgery, rat stomachs were irrigated for 3 h with either simulated gastric juice or normal saline.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04629", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Carbachol concentrations in serum and urine on day 1 and 2 of hospital admission were analysed by HPLC - mass spectrometry.", "completion": "{\"entities\": [{\"text\": \"Carbachol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03200", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The incidence of coronary events was similar in both groups.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00144", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Multiple cytotoxic drug administration is the generally accepted treatment of patients with a high - risk stage of choriocarcinoma.", "completion": "{\"entities\": [{\"text\": \"choriocarcinoma\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02386", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: The administration of methylprednisolone and gentamicin in the posterior sub - Tenon' s space was related to a high incidence of side effects including nausea, vomiting, and headache", "completion": "{\"entities\": [{\"text\": \"methylprednisolone\", \"type\": \"Chemical\"}, {\"text\": \"gentamicin\", \"type\": \"Chemical\"}, {\"text\": \"nausea, vomiting\", \"type\": \"Disease\"}, {\"text\": \"headache\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-05103", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 002 ). The EDITS scores were 67.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04926", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pain intensity on a 0 to 10 numerical scale; nausea and vomiting, drowsiness, confusion, and dry mouth, using a scale from 0 to 3 (not at all, slight, a lot, awful ); Mini - Mental State Examination (MMSE )(0 - 30 ); and arterial pressure were recorded before administration of drugs (T0) and after 30 minutes (T30 ), 60 minutes (T60 ), 120 minutes (T120 ), and 180 minutes (T180 ). Ketamine, but not saline solution, significantly reduced the pain intensity in almost all the patients at both doses.", "completion": "{\"entities\": [{\"text\": \"Pain\", \"type\": \"Disease\"}, {\"text\": \"nausea\", \"type\": \"Disease\"}, {\"text\": \"vomiting\", \"type\": \"Disease\"}, {\"text\": \"confusion\", \"type\": \"Disease\"}, {\"text\": \"dry mouth\", \"type\": \"Disease\"}, {\"text\": \"Ketamine\", \"type\": \"Chemical\"}, {\"text\": \"pain\", \"type\": \"Disease\"}]}", "n_entities": 7}
{"ref": "bc5cdr-train-02858", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This indicates reversibility in captopril - induced renal failure", "completion": "{\"entities\": [{\"text\": \"captopril\", \"type\": \"Chemical\"}, {\"text\": \"renal failure\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00797", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: Direct thrombin inhibitors (DTIs) provide an alternative method of anticoagulation for patients with a history of heparin - induced thrombocytopenia (HIT) or HIT with thrombosis (HITT) undergoing cardiopulmonary bypass (CPB ). In the following report, a 65 - year - old critically ill patient with a suspected history of HITT was administered argatroban for anticoagulation on bypass during heart transplantation.", "completion": "{\"entities\": [{\"text\": \"heparin\", \"type\": \"Chemical\"}, {\"text\": \"thrombocytopenia\", \"type\": \"Disease\"}, {\"text\": \"HIT\", \"type\": \"Disease\"}, {\"text\": \"thrombosis\", \"type\": \"Disease\"}, {\"text\": \"HITT\", \"type\": \"Disease\"}, {\"text\": \"critically ill\", \"type\": \"Disease\"}, {\"text\": \"argatroban\", \"type\": \"Chemical\"}]}", "n_entities": 7}
{"ref": "bc5cdr-train-03588", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Epileptic seizures following cortical application of fibrin sealants containing tranexamic acid in rats.", "completion": "{\"entities\": [{\"text\": \"Epileptic seizures\", \"type\": \"Disease\"}, {\"text\": \"tranexamic acid\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02200", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In vivo protection of dna damage associated apoptotic and necrotic cell deaths during acetaminophen - induced nephrotoxicity, amiodarone - induced lung toxicity and doxorubicin - induced cardiotoxicity by a novel IH636 grape seed proanthocyanidin extract.", "completion": "{\"entities\": [{\"text\": \"necrotic\", \"type\": \"Disease\"}, {\"text\": \"acetaminophen\", \"type\": \"Chemical\"}, {\"text\": \"nephrotoxicity\", \"type\": \"Disease\"}, {\"text\": \"amiodarone\", \"type\": \"Chemical\"}, {\"text\": \"lung toxicity\", \"type\": \"Disease\"}, {\"text\": \"doxorubicin\", \"type\": \"Chemical\"}, {\"text\": \"cardiotoxicity\", \"type\": \"Disease\"}, {\"text\": \"IH636 grape seed proanthocyanidin extract\", \"type\": \"Chemical\"}]}", "n_entities": 8}
{"ref": "bc5cdr-train-01952", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A delayed complication in nine patients has been unilateral loss of vision secondary to a retinal vasculitis.", "completion": "{\"entities\": [{\"text\": \"loss of vision\", \"type\": \"Disease\"}, {\"text\": \"retinal vasculitis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01123", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, three case control studies, one each in North Carolina, northern Maryland, and West Berlin, Germany, showed that habitual use of acetaminophen is also associated with chronic renal failure and ESRD, with a relative risk in the range of 2 to 4.", "completion": "{\"entities\": [{\"text\": \"acetaminophen\", \"type\": \"Chemical\"}, {\"text\": \"chronic renal failure\", \"type\": \"Disease\"}, {\"text\": \"ESRD\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00898", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Repeated cerebral perfusion SPECT scans revealed decreased basal ganglia perfusion while the movement disorder was present, and a return to normal perfusion when the rabbit syndrome", "completion": "{\"entities\": [{\"text\": \"decreased basal ganglia perfusion\", \"type\": \"Disease\"}, {\"text\": \"movement disorder\", \"type\": \"Disease\"}, {\"text\": \"rabbit syndrome\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01883", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The aim of the study was to clarify the incidence and severity of adverse cardiac effects to this treatment.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03004", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: No thrombi or signs of microangiopathies were observed in arterial vessels.", "completion": "{\"entities\": [{\"text\": \"thrombi\", \"type\": \"Disease\"}, {\"text\": \"microangiopathies\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04267", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The prolactinoma cells at this time were well granulated, with vesiculated rough endoplasmic reticulum and markedly dilated Golgi cisternae.", "completion": "{\"entities\": [{\"text\": \"prolactinoma\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03149", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Given its excellent tolerance profile and low toxicity, further evaluation of VNB", "completion": "{\"entities\": [{\"text\": \"toxicity\", \"type\": \"Disease\"}, {\"text\": \"VNB\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04611", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 mm for control subjects (p less than 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03468", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: There was a significant reduction of thymidine incorporation into both erythroid and endothelial cells in cultures pre - treated with IGF - IL - 3 and EPO.", "completion": "{\"entities\": [{\"text\": \"thymidine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00063", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Ocular and auditory toxicity in hemodialyzed patients receiving desferrioxamine.", "completion": "{\"entities\": [{\"text\": \"Ocular and auditory toxicity\", \"type\": \"Disease\"}, {\"text\": \"desferrioxamine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01811", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: There is evidence that growth hormone may be related to the progression of weakness in Duchenne dystrophy.", "completion": "{\"entities\": [{\"text\": \"weakness\", \"type\": \"Disease\"}, {\"text\": \"Duchenne dystrophy\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04179", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 253 min, respectively) but prolonged after bupivacaine (200 and 299 min, respectively; P < 0.", "completion": "{\"entities\": [{\"text\": \"bupivacaine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04145", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND AND PURPOSE: The Intravenous Nimodipine West European Stroke Trial (INWEST) found a correlation between nimodipine - induced reduction in blood pressure (BP) and an unfavorable outcome in acute stroke.", "completion": "{\"entities\": [{\"text\": \"Nimodipine\", \"type\": \"Chemical\"}, {\"text\": \"Stroke\", \"type\": \"Disease\"}, {\"text\": \"nimodipine\", \"type\": \"Chemical\"}, {\"text\": \"reduction in blood pressure\", \"type\": \"Disease\"}, {\"text\": \"acute stroke\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-01185", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Eight patients were dead in the last follow - up; two of them died of treatment - related toxicity.", "completion": "{\"entities\": [{\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03570", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The haemodynamic effects of propofol in combination with ephedrine in elderly patients (ASA groups 3 and 4 ). The marked vasodilator and negative inotropic effects of propofol are disadvantages in frail elderly patients.", "completion": "{\"entities\": [{\"text\": \"propofol\", \"type\": \"Chemical\"}, {\"text\": \"ephedrine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03783", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: There is a need for a well - defined animal model in which these blood dyscrasias can be studied.", "completion": "{\"entities\": [{\"text\": \"blood dyscrasias\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00792", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Ecstasy - specific hypoactivity was evident in the right dorsal anterior cingulated cortex (ACC) and left posterior cingulated cortex.", "completion": "{\"entities\": [{\"text\": \"Ecstasy\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02047", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Alterations in the structural elements of the BBB coexisted with marked lesions of neurons of the cerebellum (Purkinje cells are earliest ). In electron micrographs both luminal and antiluminal sides of the BBB of the cerebellar cortex had similar lesions.", "completion": "{\"entities\": [{\"text\": \"luminal\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03616", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Male Sprague - Dawley rats were treated with D-penicillamine (D-pen) 500 mg / kg / day for 10 or 42 days.", "completion": "{\"entities\": [{\"text\": \"D-pen\", \"type\": \"Chemical\"}, {\"text\": \"D-penicillamine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01457", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Safety and adverse effects associated with raloxifene: multiple outcomes of raloxifene evaluation.", "completion": "{\"entities\": [{\"text\": \"raloxifene\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04588", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The results evinced no enhancement of the hepatocarcinogenicity of the choline - devoid diet by phenobarbital", "completion": "{\"entities\": [{\"text\": \"choline\", \"type\": \"Chemical\"}, {\"text\": \"phenobarbital\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04771", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Of those positive for p24 antigen at the commencement of the study 67% showed a positive response, and this was most likely in those with CD4 + lymphocyte subset counts above 100 mm3.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04950", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: in 5 men and was normal in 2 at repeat determination.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03177", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The ocular hypotensive effects were statistically significant for apraclonidine - treated eyes throughout the study and also statistically significant for contralateral eyes from three hours after topical administration of 1% apraclonidine.", "completion": "{\"entities\": [{\"text\": \"ocular hypotensive\", \"type\": \"Disease\"}, {\"text\": \"apraclonidine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02497", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Striatal microglia expressing eGFP constitutively show morphological changes after METH that are characteristic of activation.", "completion": "{\"entities\": [{\"text\": \"METH\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02068", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Although the exact mechanism of hepatotoxicity of these agents is not known, the results suggest that trifluoroacetyl", "completion": "{\"entities\": [{\"text\": \"hepatotoxicity\", \"type\": \"Disease\"}, {\"text\": \"trifluoroacetyl\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01638", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Neuropsychological testing showed impaired word fluency, psychomotor speed and working memory.", "completion": "{\"entities\": [{\"text\": \"impaired word fluency, psychomotor speed and working memory\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00328", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Crescentic fibrillary glomerulonephritis associated with intermittent rifampin therapy for pulmonary tuberculosis.", "completion": "{\"entities\": [{\"text\": \"glomerulonephritis\", \"type\": \"Disease\"}, {\"text\": \"rifampin\", \"type\": \"Chemical\"}, {\"text\": \"pulmonary tuberculosis\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04905", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: We present the first case report of a woman with hyperthyroidism treated with propylthiouracil in whom a syndrome of pericarditis, fever, and glomerulonephritis developed.", "completion": "{\"entities\": [{\"text\": \"hyperthyroidism\", \"type\": \"Disease\"}, {\"text\": \"propylthiouracil\", \"type\": \"Chemical\"}, {\"text\": \"pericarditis\", \"type\": \"Disease\"}, {\"text\": \"fever\", \"type\": \"Disease\"}, {\"text\": \"glomerulonephritis\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-04344", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSION: This study establishes a TAA model by periarterial CaCl(2)", "completion": "{\"entities\": [{\"text\": \"TAA\", \"type\": \"Disease\"}, {\"text\": \"CaCl(2)\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00097", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Clotiazepam withdrawal was followed by prompt recovery.", "completion": "{\"entities\": [{\"text\": \"Clotiazepam\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01634", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: There are also implications for recommendations and regulations regarding the use of clozapine", "completion": "{\"entities\": [{\"text\": \"clozapine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02335", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: mRNA levels for the alpha5 and the beta4 subunits were unchanged in alpha3 +/- brains.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04368", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In this study, the hypothesis was tested that there is a sexual dimorphism in HS - induced upregulation of intrarenal angiotensinogen mediated by testosterone that also causes increases in BP and renal injury.", "completion": "{\"entities\": [{\"text\": \"testosterone\", \"type\": \"Chemical\"}, {\"text\": \"renal injury\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01836", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cause of death among patients with Parkinson's disease: a rare mortality due to cerebral haemorrhage.", "completion": "{\"entities\": [{\"text\": \"death\", \"type\": \"Disease\"}, {\"text\": \"Parkinson's disease\", \"type\": \"Disease\"}, {\"text\": \"cerebral haemorrhage\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01822", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pentoxifylline (Trental) does not inhibit dipyridamole - induced coronary hyperemia: implications for dipyridamole - thallium - 201 myocardial imaging.", "completion": "{\"entities\": [{\"text\": \"Pentoxifylline\", \"type\": \"Chemical\"}, {\"text\": \"Trental\", \"type\": \"Chemical\"}, {\"text\": \"dipyridamole\", \"type\": \"Chemical\"}, {\"text\": \"hyperemia\", \"type\": \"Disease\"}, {\"text\": \"thallium\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-00710", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This was a case of acute palsy of the recurrent laryngeal nerve and superimposed severe acute sensorimotor axonal polyneuropathy caused by high - dose disulfiram", "completion": "{\"entities\": [{\"text\": \"palsy\", \"type\": \"Disease\"}, {\"text\": \"polyneuropathy\", \"type\": \"Disease\"}, {\"text\": \"disulfiram\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-reassigned-01784", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A case of thoracic hematomyelia", "completion": "{\"entities\": [{\"text\": \"thoracic hematomyelia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04909", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A literature review revealed no prior reports of pericarditis in anti - MPO pANCA - positive vasculitis associated with propylthio- uracil therapy.", "completion": "{\"entities\": [{\"text\": \"pericarditis\", \"type\": \"Disease\"}, {\"text\": \"vasculitis\", \"type\": \"Disease\"}, {\"text\": \"propylthio- uracil\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-reassigned-00988", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The patient also received simvastatin.", "completion": "{\"entities\": [{\"text\": \"simvastatin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04106", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Recurrence of hepatitis attack might have been avoided if the initial incident had been communicated to the attending physician who prescribed telithromycin the second time.", "completion": "{\"entities\": [{\"text\": \"hepatitis\", \"type\": \"Disease\"}, {\"text\": \"telithromycin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01054", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Following discontinuation of SNP, blood pressure in the control animals rebounded to 94 torr, as compared with 78 torr in the saralasin - treated rats.", "completion": "{\"entities\": [{\"text\": \"SNP\", \"type\": \"Chemical\"}, {\"text\": \"saralasin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00433", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The newer atypical agents have a lower risk of EPS, but are associated in varying degrees with sedation, cardiovascular effects, anticholinergic effects, weight gain, sexual dysfunction, hepatic effects, lowered seizure threshold (primarily clozapine ), and agranulocytosis (clozapine", "completion": "{\"entities\": [{\"text\": \"EPS\", \"type\": \"Disease\"}, {\"text\": \"weight gain\", \"type\": \"Disease\"}, {\"text\": \"sexual dysfunction\", \"type\": \"Disease\"}, {\"text\": \"seizure\", \"type\": \"Disease\"}, {\"text\": \"clozapine\", \"type\": \"Chemical\"}, {\"text\": \"agranulocytosis\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-01284", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cocaine' s ability to interact with sigma receptors suggests that these proteins mediate some of its behavioral effects.", "completion": "{\"entities\": [{\"text\": \"Cocaine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02159", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Under controlled conditions, infant rats emit ultrasonic vocalizations during extreme cold exposure and after administration of the alpha (2) adrenoceptor agonist, clonidine.", "completion": "{\"entities\": [{\"text\": \"clonidine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02435", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Mutations associated with lamivudine - resistance in therapy - na ve hepatitis B virus (HBV) infected patients with and without HIV co-infection: implications for antiretroviral therapy in HBV and HIV co-infected South African patients.", "completion": "{\"entities\": [{\"text\": \"lamivudine\", \"type\": \"Chemical\"}, {\"text\": \"na\", \"type\": \"Chemical\"}, {\"text\": \"hepatitis B virus (HBV) infected\", \"type\": \"Disease\"}, {\"text\": \"HIV co-infection\", \"type\": \"Disease\"}, {\"text\": \"HBV and HIV co-infected\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-00225", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: administration of flunitrazepam in volunteers.", "completion": "{\"entities\": [{\"text\": \"flunitrazepam\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-reassigned-05740", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Heparin - induced thrombocytopenia: a practical review.", "completion": "{\"entities\": [{\"text\": \"Heparin\", \"type\": \"Chemical\"}, {\"text\": \"thrombocytopenia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04189", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: OBJECTIVE: To report a case of venlafaxine overdose.", "completion": "{\"entities\": [{\"text\": \"venlafaxine\", \"type\": \"Chemical\"}, {\"text\": \"overdose\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03740", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Severe ocular and orbital toxicity after intracarotid injection of carboplatin for recurrent glioblastomas.", "completion": "{\"entities\": [{\"text\": \"ocular and orbital toxicity\", \"type\": \"Disease\"}, {\"text\": \"carboplatin\", \"type\": \"Chemical\"}, {\"text\": \"glioblastomas\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01237", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Circumstances leading to this event and the mechanisms enabling a neuromuscular blockade", "completion": "{\"entities\": [{\"text\": \"neuromuscular blockade\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00172", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: AV block, severe hypotension, and impairment of ventricular function.", "completion": "{\"entities\": [{\"text\": \"AV block\", \"type\": \"Disease\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}, {\"text\": \"impairment of ventricular function\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02850", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pain recall after one week was similarly precise (magnitude: p < 0.", "completion": "{\"entities\": [{\"text\": \"Pain\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03256", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Apamin, a selective blocker of calcium - dependent potassium channels, was administered intracerebroventricularly in rats anesthetized with 0.", "completion": "{\"entities\": [{\"text\": \"Apamin\", \"type\": \"Chemical\"}, {\"text\": \"calcium\", \"type\": \"Chemical\"}, {\"text\": \"potassium\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02580", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: To date there has been little documentation of clinically significant proteinuria linked with the use of sirolimus.", "completion": "{\"entities\": [{\"text\": \"proteinuria\", \"type\": \"Disease\"}, {\"text\": \"sirolimus\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00377", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 01) decrease in movement in coniine and nicotine sulfate treated chicks as determined by ultrasound.", "completion": "{\"entities\": [{\"text\": \"coniine\", \"type\": \"Chemical\"}, {\"text\": \"nicotine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-04339", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Trazodone at 2.", "completion": "{\"entities\": [{\"text\": \"Trazodone\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00288", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 2% and / or aspirin at a level of 0.", "completion": "{\"entities\": [{\"text\": \"aspirin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00682", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Associations between use of benzodiazepines or related drugs and health, physical abilities and cognitive function: a non - randomised clinical study in the elderly.", "completion": "{\"entities\": [{\"text\": \"benzodiazepines\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02949", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Three months after deafening, A1 was remapped.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04167", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 ml 2% lidocaine in 7.", "completion": "{\"entities\": [{\"text\": \"lidocaine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02903", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: There are no similar reports with renal transplantation.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04527", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 ), let the embryos develop exo utero until E18.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04766", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The use and toxicity of didanosine (ddI) in HIV antibody-positive individuals intolerant to zidovudine (AZT) One hundred and fifty - one patients intolerant to zidovudine (AZT) received didanosine (ddI) to a maximum dose of 12.", "completion": "{\"entities\": [{\"text\": \"toxicity\", \"type\": \"Disease\"}, {\"text\": \"didanosine\", \"type\": \"Chemical\"}, {\"text\": \"ddI\", \"type\": \"Chemical\"}, {\"text\": \"HIV antibody-positive\", \"type\": \"Disease\"}, {\"text\": \"zidovudine\", \"type\": \"Chemical\"}, {\"text\": \"AZT\", \"type\": \"Chemical\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-03518", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 - T whole - body system using a circular polarized head coil.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03817", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Finally, pruritus disappeared within 19 months, and liver tests returned to normal 27 months after the onset of hepatitis.", "completion": "{\"entities\": [{\"text\": \"pruritus\", \"type\": \"Disease\"}, {\"text\": \"hepatitis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01958", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Intrarenal compared with intravenous infusion of noradrenaline caused higher plasma noradrenaline concentrations and a shift of the plasma noradrenaline concentration - blood pressure effect curve towards lower plasma noradrenaline levels.", "completion": "{\"entities\": [{\"text\": \"noradrenaline\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02524", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 7) and the sum of regurgitation grades (n = 2.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04337", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: MMP - TIMP and ADAM mRNAs were semi - quantitatively analyzed and protein expressions were determined by immunohistochemistry.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04146", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We sought to confirm this correlation with and without adjustment for prognostic variables and to investigate outcome in subgroups with increasing levels of BP reduction.", "completion": "{\"entities\": [{\"text\": \"BP reduction\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05152", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pain intensity and pain period were statistically significantly lower for the 30 - second injection than for the 10 - second injection.", "completion": "{\"entities\": [{\"text\": \"Pain\", \"type\": \"Disease\"}, {\"text\": \"pain\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01553", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: She had a gradual return of motor function and ability of feeling Foley catheter.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02540", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The timing of papaverine application and ongoing operative events was reviewed relative to changes in neurophysiological recordings.", "completion": "{\"entities\": [{\"text\": \"papaverine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00585", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Basal CGRP concentration was significantly higher and platelet 5-HT content tended to be lower in subjects who experienced a migraine attack.", "completion": "{\"entities\": [{\"text\": \"CGRP\", \"type\": \"Chemical\"}, {\"text\": \"5-HT\", \"type\": \"Chemical\"}, {\"text\": \"migraine\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00364", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The purpose of this study was to evaluate and compare the effects of coniine and nicotine in the developing chick.", "completion": "{\"entities\": [{\"text\": \"coniine\", \"type\": \"Chemical\"}, {\"text\": \"nicotine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03219", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Preclinical toxicologic investigation suggested that a new calcium channel blocker, Ro 40-5967, induced cardiovascular alterations in rat fetuses exposed to this agent during organogenesis.", "completion": "{\"entities\": [{\"text\": \"calcium\", \"type\": \"Chemical\"}, {\"text\": \"Ro 40-5967\", \"type\": \"Chemical\"}, {\"text\": \"cardiovascular alterations\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04554", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We describe 3 episodes of microangiopathic hemolytic anemia (MAHA) in 2 solid organ recipients under FK506 (tacrolimus) therapy.", "completion": "{\"entities\": [{\"text\": \"microangiopathic hemolytic anemia\", \"type\": \"Disease\"}, {\"text\": \"MAHA\", \"type\": \"Disease\"}, {\"text\": \"FK506\", \"type\": \"Chemical\"}, {\"text\": \"tacrolimus\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-reassigned-03206", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: No serious adverse events were observed.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01239", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The epidemiological studies that assessed the risk of venous thromboembolism (VTE) associated with newer oral contraceptives (OC) did not distinguish between patterns of OC use, namely first - time users, repeaters and switchers.", "completion": "{\"entities\": [{\"text\": \"venous thromboembolism\", \"type\": \"Disease\"}, {\"text\": \"VTE\", \"type\": \"Disease\"}, {\"text\": \"oral contraceptives\", \"type\": \"Chemical\"}, {\"text\": \"OC\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01924", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Haematological complications were not troublesome and results of biochemical liver function tests remained normal.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02912", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Three patients on acetazolamide (15 %) developed renal calculi.", "completion": "{\"entities\": [{\"text\": \"acetazolamide\", \"type\": \"Chemical\"}, {\"text\": \"renal calculi\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02006", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Sodium bicarbonate alleviates penile pain induced by intracavernous injections for erectile dysfunction.", "completion": "{\"entities\": [{\"text\": \"Sodium bicarbonate\", \"type\": \"Chemical\"}, {\"text\": \"penile pain\", \"type\": \"Disease\"}, {\"text\": \"erectile dysfunction\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03537", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: cTnI was measured with Access (R )(ng / ml) and a research immunoassay (pg / ml ), and compared with cTnT, CK - MB mass and CK.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01959", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These results suggest that hypertension after chronic intrarenal noradrenaline infusion is produced by relatively higher levels of circulating noradrenaline", "completion": "{\"entities\": [{\"text\": \"hypertension\", \"type\": \"Disease\"}, {\"text\": \"noradrenaline\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01843", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 3 %). Cerebral haemorrhage was the 11th most frequent cause of death, accounting for only 0.", "completion": "{\"entities\": [{\"text\": \"Cerebral haemorrhage\", \"type\": \"Disease\"}, {\"text\": \"death\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03967", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: When discharged less than 24 hours later, he was receiving metoprolol and aspirin, with follow - up plans for echocardiography and nuclear imaging to assess perfusion.", "completion": "{\"entities\": [{\"text\": \"metoprolol\", \"type\": \"Chemical\"}, {\"text\": \"aspirin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-reassigned-03481", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Meloxicam - induced liver toxicity.", "completion": "{\"entities\": [{\"text\": \"Meloxicam\", \"type\": \"Chemical\"}, {\"text\": \"liver toxicity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02281", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These findings suggest that the effects of estradiol on seizure", "completion": "{\"entities\": [{\"text\": \"estradiol\", \"type\": \"Chemical\"}, {\"text\": \"seizure\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03734", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In vitro, gamma-HCH, pentylenetetrazol and picrotoxin were shown to inhibit 3H-TBOB binding in mouse whole brain, with IC50 values of 4.", "completion": "{\"entities\": [{\"text\": \"gamma-HCH\", \"type\": \"Chemical\"}, {\"text\": \"pentylenetetrazol\", \"type\": \"Chemical\"}, {\"text\": \"picrotoxin\", \"type\": \"Chemical\"}, {\"text\": \"3H-TBOB\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03008", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A 54 - year - old hypothyroid male taking thyroxine and simvastatin presented with bilateral leg compartment syndrome and myonecrosis.", "completion": "{\"entities\": [{\"text\": \"hypothyroid\", \"type\": \"Disease\"}, {\"text\": \"thyroxine\", \"type\": \"Chemical\"}, {\"text\": \"simvastatin\", \"type\": \"Chemical\"}, {\"text\": \"compartment syndrome\", \"type\": \"Disease\"}, {\"text\": \"myonecrosis\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-02194", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Surprisingly, the first dose of 50 mg of losartan resulted in a sudden anuria, which lasted eight hours despite high - dose furosemide and amine infusion.", "completion": "{\"entities\": [{\"text\": \"losartan\", \"type\": \"Chemical\"}, {\"text\": \"anuria\", \"type\": \"Disease\"}, {\"text\": \"furosemide\", \"type\": \"Chemical\"}, {\"text\": \"amine\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04570", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: in 6 increments of 100 mg / kg each over 30 hr, on mouse motility and whole brain content of selected biogenic amines and major metabolites was studied in 4 strains of mice.", "completion": "{\"entities\": [{\"text\": \"amines\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04064", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Over the long - term chronic phase (120 days after transplantation ), only 25% of BMC - treated epileptic animals had seizures, but with a lower frequency and duration compared to the epileptic control group.", "completion": "{\"entities\": [{\"text\": \"epileptic\", \"type\": \"Disease\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03144", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Six of 30 patients (20 %) without prior chemotherapy achieved a partial response (PR )(95% confidence interval [CI ], 8% to 39 %). The median duration of response was 21 weeks (range, 17 to 28 ). One of 16 patients (6 %) with prior chemotherapy had a complete response (CR) of 31 weeks' duration (95% CI, 0% to 30 %). The overall response rate (World Health Organization [WHO] criteria) was 15 %(CR, 2 %; PR 13 %; 95% CI, 6% to 29 %). The median dose - intensity (DI) was 20 mg / m2 / wk.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01557", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: High - dose testosterone is associated with atherosclerosis in postmenopausal women.", "completion": "{\"entities\": [{\"text\": \"testosterone\", \"type\": \"Chemical\"}, {\"text\": \"atherosclerosis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04752", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Frequency of absences increased in four children treated with carbamazepine and two of these developed myoclonic jerks, which resolved on withdrawal of carbamazepine.", "completion": "{\"entities\": [{\"text\": \"carbamazepine\", \"type\": \"Chemical\"}, {\"text\": \"myoclonic jerks\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01862", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Suppression of irCRF secretion in response to nitroprusside - induced hypotension is observed and occurs at a plasma corticosterone", "completion": "{\"entities\": [{\"text\": \"nitroprusside\", \"type\": \"Chemical\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}, {\"text\": \"corticosterone\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01307", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These data underline the need to maximize the therapeutic ratio with respect to TDP", "completion": "{\"entities\": [{\"text\": \"TDP\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02775", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Ninety - nine percent (sixty - eight) of the sixty - nine parents present during the reduction were pleased with the sedation and would allow it to be used again in a similar situation.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03391", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Valproic acid induced encephalopathy -- 19 new cases in Germany from 1994 to 2003 -- a side effect associated to VPA - therapy not only in young children.", "completion": "{\"entities\": [{\"text\": \"Valproic acid\", \"type\": \"Chemical\"}, {\"text\": \"encephalopathy\", \"type\": \"Disease\"}, {\"text\": \"VPA\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00101", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Two of 14 patients with Cushing's syndrome treated on a long - term basis with ketoconazole developed sustained hypertension.", "completion": "{\"entities\": [{\"text\": \"Cushing's syndrome\", \"type\": \"Disease\"}, {\"text\": \"ketoconazole\", \"type\": \"Chemical\"}, {\"text\": \"hypertension\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02333", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Using in situ hybridization probes for the alpha3 and alpha5 subunits, we showed that alpha5 mRNA levels are unchanged, whereas alpha3 mRNA levels are selectively decreased in the mitral cell layer of the olfactory bulb, and the inferior and the superior colliculus of beta4 -/- brains.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04459", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We aimed to determine the causes of thrombotic microangiopathy in a population of renal transplantation recipients and discuss the literature.", "completion": "{\"entities\": [{\"text\": \"thrombotic microangiopathy\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04560", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We report a case of variant ventricular tachycardia induced by desipramine toxicity.", "completion": "{\"entities\": [{\"text\": \"ventricular tachycardia\", \"type\": \"Disease\"}, {\"text\": \"desipramine\", \"type\": \"Chemical\"}, {\"text\": \"toxicity\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01033", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Small - and medium - sized hepatic veins were blocked by thrombosis", "completion": "{\"entities\": [{\"text\": \"thrombosis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02098", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Primary pulmonary hypertension is a rare, progressive and incurable disease, which has been associated with the intake of appetite suppressant drugs.", "completion": "{\"entities\": [{\"text\": \"Primary pulmonary hypertension\", \"type\": \"Disease\"}, {\"text\": \"appetite suppressant\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00204", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The rapid alternations of rigidity", "completion": "{\"entities\": [{\"text\": \"rigidity\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04415", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cell extracts were harvested, and lipid or total RNA was isolated.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00796", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Prolonged elevation of plasma argatroban in a cardiac transplant patient with a suspected history of heparin - induced thrombocytopenia with thrombosis.", "completion": "{\"entities\": [{\"text\": \"argatroban\", \"type\": \"Chemical\"}, {\"text\": \"heparin\", \"type\": \"Chemical\"}, {\"text\": \"thrombocytopenia\", \"type\": \"Disease\"}, {\"text\": \"thrombosis\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02861", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This is an addition to the list of drugs that must be considered in the evaluation of chronic liver disease", "completion": "{\"entities\": [{\"text\": \"liver disease\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00275", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: There were no clinically important changes in laboratory parameters.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04721", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 34 %), ten of which were mild reactions such as nausea, exanthema, urtication, itchiness, and urgency to defecate, and did not require treatment.", "completion": "{\"entities\": [{\"text\": \"nausea\", \"type\": \"Disease\"}, {\"text\": \"exanthema\", \"type\": \"Disease\"}, {\"text\": \"urtication\", \"type\": \"Disease\"}, {\"text\": \"itchiness\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04755", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Hemolytic anemia associated with the use of omeprazole.", "completion": "{\"entities\": [{\"text\": \"Hemolytic anemia\", \"type\": \"Disease\"}, {\"text\": \"omeprazole\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00764", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: The mechanisms underlying heart failure induced by adriamycin are very complicated and still unclear.", "completion": "{\"entities\": [{\"text\": \"heart failure\", \"type\": \"Disease\"}, {\"text\": \"adriamycin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04963", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Patients in Group C received 2 ml normal saline, Group L, 2 ml, lidocaine 2 %(40 mg) and Group T, 2 ml thiopentone 2.", "completion": "{\"entities\": [{\"text\": \"lidocaine\", \"type\": \"Chemical\"}, {\"text\": \"thiopentone\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04258", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Delaying induction of anesthesia should be considered whenever possible.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-reassigned-04557", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 8% of the whole series.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04216", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 53 )) and all had abnormally rapid cholesterol microcrystal nucleation times (< 4 days (range 1 - 4 )), whilst in four, the bile contained cholesterol microcrystals immediately after sampling.", "completion": "{\"entities\": [{\"text\": \"cholesterol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03574", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, marked tachycardia associated with the use of ephedrine in combination with propofol occurred in the majority of patients, occasionally reaching high levels in individual patients.", "completion": "{\"entities\": [{\"text\": \"tachycardia\", \"type\": \"Disease\"}, {\"text\": \"ephedrine\", \"type\": \"Chemical\"}, {\"text\": \"propofol\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03037", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The authors present three patients with de novo absence epilepsy after administration of carbamazepine and vigabatrin.", "completion": "{\"entities\": [{\"text\": \"absence epilepsy\", \"type\": \"Disease\"}, {\"text\": \"carbamazepine\", \"type\": \"Chemical\"}, {\"text\": \"vigabatrin\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03836", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After cessation of the sulfasalazine and completion of a six - week course of corticosteroids, these problems resolved over a period of four to six months.", "completion": "{\"entities\": [{\"text\": \"sulfasalazine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02346", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A case of valproate - induced encephalopathy", "completion": "{\"entities\": [{\"text\": \"valproate\", \"type\": \"Chemical\"}, {\"text\": \"encephalopathy\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01056", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This demonstrates the participation of the renin -- angiotensin system in antagonizing the combined hypotensive effects of halothane and SNP", "completion": "{\"entities\": [{\"text\": \"angiotensin\", \"type\": \"Chemical\"}, {\"text\": \"hypotensive\", \"type\": \"Disease\"}, {\"text\": \"halothane\", \"type\": \"Chemical\"}, {\"text\": \"SNP\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-reassigned-05246", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The hazard decreased 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00734", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: OBJECTIVE: To report a case of central retinal vein occlusion associated with clomiphene citrate (CC ). DESIGN: Case study.", "completion": "{\"entities\": [{\"text\": \"retinal vein occlusion\", \"type\": \"Disease\"}, {\"text\": \"clomiphene citrate\", \"type\": \"Chemical\"}, {\"text\": \"CC\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00658", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 8 mg / dL before SRL therapy and 2.", "completion": "{\"entities\": [{\"text\": \"SRL\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00110", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The contents of albumin in the lungs were not changed, indicating that Captopril did not influence the extravasation of protein.", "completion": "{\"entities\": [{\"text\": \"Captopril\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03488", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In contrast, in normal - salt rats creatinine clearance was decreased but to a lesser extent at week 2 and 3, and in salt - loaded rats creatinine clearance did not change for 2 weeks and was decreased by 43% at week 3.", "completion": "{\"entities\": [{\"text\": \"creatinine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03517", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Five females and 6 males, 21 - 59 years of age, were examined with a 1.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00128", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This treatment with CBZ had no apparent adverse effect on folate concentrations in the rat, and, indeed, the folate", "completion": "{\"entities\": [{\"text\": \"CBZ\", \"type\": \"Chemical\"}, {\"text\": \"folate\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04583", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: An experiment was performed to test whether inclusion of phenobarbital in a choline - devoid diet would increase the hepatocarcinogenicity of the diet.", "completion": "{\"entities\": [{\"text\": \"phenobarbital\", \"type\": \"Chemical\"}, {\"text\": \"choline\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00278", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The effects of oral doses of diazepam (single dose of 10 mg and a median dose of 30 mg / day for 2 weeks) and propranolol (single dose of 80 mg and a median dose of 240 mg / day for 2 weeks) on psychological performance of patients with panic disorders and agoraphobia were investigated in a double - blind, randomized and crossover design.", "completion": "{\"entities\": [{\"text\": \"diazepam\", \"type\": \"Chemical\"}, {\"text\": \"propranolol\", \"type\": \"Chemical\"}, {\"text\": \"panic disorders\", \"type\": \"Disease\"}, {\"text\": \"agoraphobia\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03844", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Nonpharmacologic concerns can help the Parkinson's disease", "completion": "{\"entities\": [{\"text\": \"Parkinson's disease\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00708", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Laryngoscopy revealed asymmetric vocal fold movements during phonation.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04353", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Forty - three ovarian cancer patients were available for analysis following six cycles of the same PAC - containing regimen: 23 had been supplemented by glutamate all along the treatment period, at a daily dose of three times 500 mg (group G ), and 20 had received a placebo (group P ). Patients were evaluated by neurological examinations, questionnaires and sensory - motor nerve conduction studies.", "completion": "{\"entities\": [{\"text\": \"ovarian cancer\", \"type\": \"Disease\"}, {\"text\": \"PAC\", \"type\": \"Chemical\"}, {\"text\": \"glutamate\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00773", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSION: Autophagic cardiomyocyte death plays an important role in the pathogenesis of heart failure in rats induced by adriamycin.", "completion": "{\"entities\": [{\"text\": \"death\", \"type\": \"Disease\"}, {\"text\": \"heart failure\", \"type\": \"Disease\"}, {\"text\": \"adriamycin\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03228", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We therefore systematically analyzed the functional impact of the most prevalent immune escape variants, the sG145R and sP120T mutants, on the viral replication efficacy and antiviral drug susceptibility of common treatment - associated mutants with resistance to lamivudine (LAM) and / or HBeAg negativity.", "completion": "{\"entities\": [{\"text\": \"lamivudine\", \"type\": \"Chemical\"}, {\"text\": \"LAM\", \"type\": \"Chemical\"}, {\"text\": \"HBeAg\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03136", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In patients requiring the concurrent use of statins and CYP3A4 inhibitors, pravastatin, fluvastatin, and rosuvastatin carry the lowest risk of drug interactions; atorvastatin carries moderate risk, whereas simvastatin and lovastatin", "completion": "{\"entities\": [{\"text\": \"statins\", \"type\": \"Chemical\"}, {\"text\": \"pravastatin\", \"type\": \"Chemical\"}, {\"text\": \"fluvastatin\", \"type\": \"Chemical\"}, {\"text\": \"rosuvastatin\", \"type\": \"Chemical\"}, {\"text\": \"atorvastatin\", \"type\": \"Chemical\"}, {\"text\": \"simvastatin\", \"type\": \"Chemical\"}, {\"text\": \"lovastatin\", \"type\": \"Chemical\"}]}", "n_entities": 7}
{"ref": "bc5cdr-train-01182", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Median progression - free survival was 5 months.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00412", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We report the increased amount of motor disability in four patients with idiopathic Parkinson's disease after exposure to the antidepressant fluoxetine.", "completion": "{\"entities\": [{\"text\": \"motor disability\", \"type\": \"Disease\"}, {\"text\": \"idiopathic Parkinson's disease\", \"type\": \"Disease\"}, {\"text\": \"antidepressant\", \"type\": \"Chemical\"}, {\"text\": \"fluoxetine\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03389", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The basic mechanisms of those reactions are not yet fully understood.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-05023", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The effect of a 6 - week treatment with the calcium channel blocker nitrendipine or the angiotensin converting enzyme inhibitor enalapril on blood pressure, albuminuria, renal hemodynamics, and morphology of the nonclipped kidney was studied in rats with two - kidney, one clip renovascular hypertension.", "completion": "{\"entities\": [{\"text\": \"calcium\", \"type\": \"Chemical\"}, {\"text\": \"nitrendipine\", \"type\": \"Chemical\"}, {\"text\": \"angiotensin\", \"type\": \"Chemical\"}, {\"text\": \"enalapril\", \"type\": \"Chemical\"}, {\"text\": \"albuminuria\", \"type\": \"Disease\"}, {\"text\": \"renovascular hypertension\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-04174", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the evening of postoperative day 1, patients were evaluated for TNSs by a physician unaware of the drug administered and the details of the anesthetic procedure.", "completion": "{\"entities\": [{\"text\": \"TNSs\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00688", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Of these, nearly half (n = 78) had used BZDs / RDs before admission, and the remainder (n = 86) were non - users.", "completion": "{\"entities\": [{\"text\": \"BZDs\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00661", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Five patients displayed CAN and Kaposi's sarcoma.", "completion": "{\"entities\": [{\"text\": \"CAN\", \"type\": \"Disease\"}, {\"text\": \"Kaposi's sarcoma\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01243", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The adjusted rate ratio of VTE for repeat users of third generation OC was 0.", "completion": "{\"entities\": [{\"text\": \"VTE\", \"type\": \"Disease\"}, {\"text\": \"OC\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02935", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 mg / kg ), and 2 lethalities occurred (one IV and one PO) following the 7.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02868", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The normalized reflex amplitude was significantly higher during pain, but only at faster stretches in the painful muscle.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"painful muscle\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00615", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Abnormal processing of somatosensory inputs in the central nervous system (central sensitization) is the mechanism accounting for the enhanced pain sensitivity in the skin surrounding tissue injury (secondary hyperalgesia ). Secondary hyperalgesia shares clinical characteristics with neurogenic hyperalgesia in patients with neuropathic pain.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}, {\"text\": \"tissue injury\", \"type\": \"Disease\"}, {\"text\": \"secondary hyperalgesia\", \"type\": \"Disease\"}, {\"text\": \"Secondary hyperalgesia\", \"type\": \"Disease\"}, {\"text\": \"neurogenic hyperalgesia\", \"type\": \"Disease\"}, {\"text\": \"neuropathic pain\", \"type\": \"Disease\"}]}", "n_entities": 6}
{"ref": "bc5cdr-train-04426", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This prompted us to study the brain expression of P - glycoprotein (Pgp ), a major drug efflux transporter in many tissues, including the BBB, in TR (-) rats compared with nonmutant (wild - type) Wistar rats.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00684", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: A non - randomised clinical study of patients aged > or = 65 years admitted to acute hospital wards during 1 month.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00195", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Rats treated for 11 days with morphine and withdrawn for 36 - 40 h showed differences in the development of tolerance: about half of the animals showed a rigidity after the test dose of morphine that was not significantly less than in the controls and were akinetic (A group ). The other rats showed a strong decrease in the rigidity and the occurrence of stereotyped (S) licking and / or gnawing in presence of akinetic or hyperkinetic (K) behaviour (AS / KS group ), suggesting signs of dopaminergic activation.", "completion": "{\"entities\": [{\"text\": \"morphine\", \"type\": \"Chemical\"}, {\"text\": \"rigidity\", \"type\": \"Disease\"}, {\"text\": \"akinetic\", \"type\": \"Disease\"}, {\"text\": \"hyperkinetic\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00306", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 4 times control levels, and PRL release in vitro was significantly and consistently higher than controls, after at least 8 days of DES exposure.", "completion": "{\"entities\": [{\"text\": \"DES\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02874", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The major effect was on dystonia subscore.", "completion": "{\"entities\": [{\"text\": \"dystonia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03292", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Histological studies demonstrated that the rats developed an infarct 18 h after isoproterenol administration.", "completion": "{\"entities\": [{\"text\": \"infarct\", \"type\": \"Disease\"}, {\"text\": \"isoproterenol\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04365", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Blood pressure (BP) is more salt sensitive in men than in premenopausal women.", "completion": "{\"entities\": [{\"text\": \"salt\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00162", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Dapsone - associated Heinz body hemolytic anemia in a Cambodian woman with hemoglobin E trait.", "completion": "{\"entities\": [{\"text\": \"Dapsone\", \"type\": \"Chemical\"}, {\"text\": \"hemolytic anemia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00319", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The adenylate energy charge was found to be significantly decreased, while the phophorylcreatine mole fraction was unchanged.", "completion": "{\"entities\": [{\"text\": \"phophorylcreatine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01279", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Mild PTCR in allografts without TG did not predict renal failure or significant proteinuria after follow - up periods of between 3 months and 1 year.", "completion": "{\"entities\": [{\"text\": \"TG\", \"type\": \"Disease\"}, {\"text\": \"renal failure\", \"type\": \"Disease\"}, {\"text\": \"proteinuria\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04783", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: We observed a significant decrease in haptoglobin levels at the end of the treatment period.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03044", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Procainamide - induced polymorphous ventricular tachycardia.", "completion": "{\"entities\": [{\"text\": \"Procainamide\", \"type\": \"Chemical\"}, {\"text\": \"ventricular tachycardia\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04144", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Effect of intravenous nimodipine on blood pressure and outcome after acute stroke.", "completion": "{\"entities\": [{\"text\": \"nimodipine\", \"type\": \"Chemical\"}, {\"text\": \"acute stroke\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01263", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This concerns 2 male patients who experienced incontinence while taking venlafaxine.", "completion": "{\"entities\": [{\"text\": \"incontinence\", \"type\": \"Disease\"}, {\"text\": \"venlafaxine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03339", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This supports the assumption that differences in renal ACE activity predispose to a less favourable course of renal damage", "completion": "{\"entities\": [{\"text\": \"renal damage\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00842", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: WHAT THE READER WILL GAIN: The reader will gain better insight into the safety of capecitabine in special populations such as patients with advanced age, renal and kidney disease.", "completion": "{\"entities\": [{\"text\": \"capecitabine\", \"type\": \"Chemical\"}, {\"text\": \"renal and kidney disease\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01198", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Forty seconds after injection of suxamethonium, bradycardia and cardiac arrest occurred.", "completion": "{\"entities\": [{\"text\": \"suxamethonium\", \"type\": \"Chemical\"}, {\"text\": \"bradycardia\", \"type\": \"Disease\"}, {\"text\": \"cardiac arrest\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04861", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Safety profile of a nicotine lozenge compared with that of nicotine gum in adult smokers with underlying medical conditions: a 12 - week, randomized, open - label study.", "completion": "{\"entities\": [{\"text\": \"nicotine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03398", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This paper describes the clinical features of six children who developed the haemolytic-uraemic syndrome after treatment with metronidazole.", "completion": "{\"entities\": [{\"text\": \"haemolytic-uraemic syndrome\", \"type\": \"Disease\"}, {\"text\": \"metronidazole\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02587", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In 21 patients an alternative cause of proteinuria was either obvious or insufficient data was available to be conclusive.", "completion": "{\"entities\": [{\"text\": \"proteinuria\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01614", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Autism is a neurodevelopmental disorder presenting before 3 years of age with deficits in communication and social skills and repetitive behaviors.", "completion": "{\"entities\": [{\"text\": \"Autism\", \"type\": \"Disease\"}, {\"text\": \"neurodevelopmental disorder\", \"type\": \"Disease\"}, {\"text\": \"deficits in communication and social skills\", \"type\": \"Disease\"}, {\"text\": \"repetitive behaviors\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00430", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Thus, clinicians should address patients' concerns about adverse effects and attempt to choose medications that will improve their patients' quality of life as well as overall health.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00554", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: DISCUSSION: Cholestatic hepatitis is a rare complication of the antiplatelet agent ticlopidine; several cases have been reported but few in the English literature.", "completion": "{\"entities\": [{\"text\": \"Cholestatic hepatitis\", \"type\": \"Disease\"}, {\"text\": \"ticlopidine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02268", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In ICH induction using 0.", "completion": "{\"entities\": [{\"text\": \"ICH\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04100", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 4 mg / dL ). No toxin, alcohol, or other drugs were reported.", "completion": "{\"entities\": [{\"text\": \"alcohol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03791", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After discontinuing isoniazid therapy a similar pattern of behavior was noted that was controlled by pyridoxine.", "completion": "{\"entities\": [{\"text\": \"isoniazid\", \"type\": \"Chemical\"}, {\"text\": \"pyridoxine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02460", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In cardiac transplantation, the incidence of proteinuria associated with Srl is unknown.", "completion": "{\"entities\": [{\"text\": \"proteinuria\", \"type\": \"Disease\"}, {\"text\": \"Srl\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00630", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The donor was a 40 - year - old female, first - time apheresis platelet donor.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00151", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In view of the close time association between the start of chemotherapy and the acute onset of massive embolism other explanations, such as spontaneous necrosis, must be considered less likely.", "completion": "{\"entities\": [{\"text\": \"embolism\", \"type\": \"Disease\"}, {\"text\": \"necrosis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01874", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 mmHg, delta CVP 5.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01944", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Such treatment did not diminish the ADR antitumor activity in L1210 leukemia and in Ehrlich ascites tumor", "completion": "{\"entities\": [{\"text\": \"ADR\", \"type\": \"Chemical\"}, {\"text\": \"L1210 leukemia\", \"type\": \"Disease\"}, {\"text\": \"Ehrlich ascites tumor\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02573", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Severe and long lasting cholestasis after high - dose co-trimoxazole treatment for Pneumocystis pneumonia in HIV-infected patients -- a report of two cases.", "completion": "{\"entities\": [{\"text\": \"cholestasis\", \"type\": \"Disease\"}, {\"text\": \"co-trimoxazole\", \"type\": \"Chemical\"}, {\"text\": \"Pneumocystis pneumonia\", \"type\": \"Disease\"}, {\"text\": \"HIV-infected\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00677", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 4-DAMP inhibited the tonic contractions in controls more potently than methoctramine and pirenzepine.", "completion": "{\"entities\": [{\"text\": \"4-DAMP\", \"type\": \"Chemical\"}, {\"text\": \"methoctramine\", \"type\": \"Chemical\"}, {\"text\": \"pirenzepine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-05155", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RELEVANCE TO CLINICAL PRACTICE: When administering subcutaneous heparin", "completion": "{\"entities\": [{\"text\": \"heparin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04402", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Estradiol enhanced these effects on SOCS - 3 and CIS.", "completion": "{\"entities\": [{\"text\": \"Estradiol\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02084", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A healthy 17 - year - old male received standard intermittent doses of pethidine via a patient - controlled analgesia (PCA) pump for management of postoperative pain control.", "completion": "{\"entities\": [{\"text\": \"pethidine\", \"type\": \"Chemical\"}, {\"text\": \"postoperative pain\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01155", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: After the administration of NG, 5-FU and CY neither a statistically significant increase in creatinine concentration nor an increase in creatinine clearance was observed compared to the group receiving no cytostatics.", "completion": "{\"entities\": [{\"text\": \"NG\", \"type\": \"Chemical\"}, {\"text\": \"5-FU\", \"type\": \"Chemical\"}, {\"text\": \"CY\", \"type\": \"Chemical\"}, {\"text\": \"creatinine\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00627", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: These data lend further support to the proposal that cognitive processes mediated by the prefrontal cortex may be impaired by recreational ecstasy", "completion": "{\"entities\": [{\"text\": \"ecstasy\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01608", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, by comparing each subgroup to control group, we found statistically significant decreases of TEOAEs amplitudes at 4000Hz for all three groups.", "completion": "{\"entities\": [{\"text\": \"decreases of TEOAEs amplitudes\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04768", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Patient response was assessed using changes in CD4 + lymphocyte subset count, HIV p24 antigen, weight, and quality of life.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02697", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: To our knowledge, this is the first case report of simvastatin-ezetimibe - induced liver failure that resulted in liver transplantation.", "completion": "{\"entities\": [{\"text\": \"simvastatin-ezetimibe\", \"type\": \"Chemical\"}, {\"text\": \"liver failure\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04503", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 1 pmol / 10 000 cells per 5 minutes, respectively, at an l-arginine concentration of 300 micromol / L) nor L-arginine extraction in the forearm (at 80 minutes, placebo vs active, 1 868 904 +/- 434 962 vs 2 013 910 +/- 770 619 disintegrations per minute) was affected by cortisol treatment; ie, that L-arginine uptake is not affected by short - term cortisol treatment.", "completion": "{\"entities\": [{\"text\": \"l-arginine\", \"type\": \"Chemical\"}, {\"text\": \"L-arginine\", \"type\": \"Chemical\"}, {\"text\": \"cortisol\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03875", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Proximal muscle weakness has developed during her follow - up.", "completion": "{\"entities\": [{\"text\": \"muscle weakness\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02344", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: It is usually but not necessarily associated with hyperammonemia.", "completion": "{\"entities\": [{\"text\": \"hyperammonemia\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03601", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 mg / ml tAMCA evoked generalized seizures in all tested rats (n = 6) while the lowest concentration of tAMCA (0.", "completion": "{\"entities\": [{\"text\": \"tAMCA\", \"type\": \"Chemical\"}, {\"text\": \"generalized seizures\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02168", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In a randomized, double - blind, placebo - controlled, crossover study, we studied 12 volunteers in three experiments.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02328", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Binding of nicotine to nicotinic acetylcholine receptors (nAChRs) elicits a series of dose - dependent behaviors that go from altered exploration, sedation, and tremors, to seizures and death.", "completion": "{\"entities\": [{\"text\": \"nicotine\", \"type\": \"Chemical\"}, {\"text\": \"acetylcholine\", \"type\": \"Chemical\"}, {\"text\": \"tremors\", \"type\": \"Disease\"}, {\"text\": \"seizures\", \"type\": \"Disease\"}, {\"text\": \"death\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-04702", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Bupropion is a monocyclic antidepressant structurally related to amphetamine.", "completion": "{\"entities\": [{\"text\": \"Bupropion\", \"type\": \"Chemical\"}, {\"text\": \"antidepressant\", \"type\": \"Chemical\"}, {\"text\": \"amphetamine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00349", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: During the night clomipramine ingestion altered the complete sleep architecture in that it suppressed REM sleep and the sleep cycles and induced increased wakefulness.", "completion": "{\"entities\": [{\"text\": \"clomipramine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00994", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Intense vasospasm with threatened gangrene arose in the arm used for the infusion.", "completion": "{\"entities\": [{\"text\": \"vasospasm\", \"type\": \"Disease\"}, {\"text\": \"gangrene\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00942", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The patient' s clinical course is described and correlated with initial urodynamic studies while on prazosin and subsequent studies while taking verapamil.", "completion": "{\"entities\": [{\"text\": \"prazosin\", \"type\": \"Chemical\"}, {\"text\": \"verapamil\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00437", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the in vivo study, the administration (50 mg / kg, i.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03880", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The present study was designed to study the effect of histamine H (3 )- receptor ligands on neuroleptic - induced catalepsy, apomorphine - induced climbing behavior and amphetamine - induced locomotor activities in mice.", "completion": "{\"entities\": [{\"text\": \"histamine\", \"type\": \"Chemical\"}, {\"text\": \"catalepsy\", \"type\": \"Disease\"}, {\"text\": \"apomorphine\", \"type\": \"Chemical\"}, {\"text\": \"amphetamine\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00715", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Forty of 94 HIT patients had thrombosis at diagnosis; 54 / 94 had isolated - HIT without thrombosis.", "completion": "{\"entities\": [{\"text\": \"HIT\", \"type\": \"Disease\"}, {\"text\": \"thrombosis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04428", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Immunofluorescence staining with the MRP2 antibody was found to label a high number of microvessels throughout the brain in normal Wistar rats, whereas such labeling was absent in TR (-) rats.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03572", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The haemodynamic effects of adding 15, 20 or 25 mg of ephedrine to 200 mg of propofol were compared to control in 40 ASA 3 / 4 patients over 60 years presenting for genito - urinary surgery.", "completion": "{\"entities\": [{\"text\": \"ephedrine\", \"type\": \"Chemical\"}, {\"text\": \"propofol\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01809", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 03 ). The pH adjustment of standard lidocaine can be accomplished easily in the catheterization laboratory before injection and results in a reduction of the pain", "completion": "{\"entities\": [{\"text\": \"lidocaine\", \"type\": \"Chemical\"}, {\"text\": \"pain\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05108", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 001 ). The ASEX score and CGI - SF score were correlated (P = 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01450", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The present study was done to investigate the protective effect of TCR on experimentally induced myocardial infarction in rats.", "completion": "{\"entities\": [{\"text\": \"TCR\", \"type\": \"Chemical\"}, {\"text\": \"myocardial infarction\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01739", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A case is reported of the hemolytic uremic syndrome (HUS) in a woman taking oral contraceptives.", "completion": "{\"entities\": [{\"text\": \"hemolytic uremic syndrome\", \"type\": \"Disease\"}, {\"text\": \"HUS\", \"type\": \"Disease\"}, {\"text\": \"oral contraceptives\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02272", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Data suggest that this sensitive hemoglobin assay is useful for ICH detection, and that a model with a small ICH induced with a low - dose collagenase should be used for evaluation of drugs that may affect ICH", "completion": "{\"entities\": [{\"text\": \"ICH\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02083", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Pethidine - associated seizure in a healthy adolescent receiving pethidine for postoperative pain control.", "completion": "{\"entities\": [{\"text\": \"Pethidine\", \"type\": \"Chemical\"}, {\"text\": \"seizure\", \"type\": \"Disease\"}, {\"text\": \"pethidine\", \"type\": \"Chemical\"}, {\"text\": \"postoperative pain\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02866", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Short - latency reflex responses were evoked in the masseter and temporalis muscles by a stretch device with different velocities and displacements before, during, and after the pain.", "completion": "{\"entities\": [{\"text\": \"pain\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01414", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: His echocardiographic abnormalities and heart failure resolved after posaconazole was substituted for AmB.", "completion": "{\"entities\": [{\"text\": \"heart failure\", \"type\": \"Disease\"}, {\"text\": \"posaconazole\", \"type\": \"Chemical\"}, {\"text\": \"AmB\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01670", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 %(95% confidence interval: 2.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03552", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 007 ). cTnI (ng / ml ), CK - MB mass and CK remained unchanged in DOX rats compared with controls.", "completion": "{\"entities\": [{\"text\": \"DOX\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01235", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Accumulation of atracurium in the intravenous line led to recurarization after flushing the line in the recovery room.", "completion": "{\"entities\": [{\"text\": \"atracurium\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04438", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Chromosome substitution strains (CSS ), in which a single chromosome from one inbred strain (donor) has been transferred onto a second strain (host) by repeated backcrossing, may be used to identify quantitative trait loci (QTLs) that contribute to seizure susceptibility.", "completion": "{\"entities\": [{\"text\": \"seizure\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01162", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: Lithium remains a first - line treatment for the acute and maintenance treatment of bipolar disorder.", "completion": "{\"entities\": [{\"text\": \"Lithium\", \"type\": \"Chemical\"}, {\"text\": \"bipolar disorder\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04175", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: Nine of 30 patients receiving lidocaine experienced TNSs, 1 of 30 patients receiving prilocaine (P = 0.", "completion": "{\"entities\": [{\"text\": \"lidocaine\", \"type\": \"Chemical\"}, {\"text\": \"TNSs\", \"type\": \"Disease\"}, {\"text\": \"prilocaine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03424", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Patients likely to have both raised trough - concentrations and mental confusion are those with both severe renal and hepatic dysfunction.", "completion": "{\"entities\": [{\"text\": \"confusion\", \"type\": \"Disease\"}, {\"text\": \"renal and hepatic dysfunction\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03397", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Haemolytic-uraemic syndrome after treatment with metronidazole.", "completion": "{\"entities\": [{\"text\": \"Haemolytic-uraemic syndrome\", \"type\": \"Disease\"}, {\"text\": \"metronidazole\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00143", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Death from chemotherapy in gestational trophoblastic disease.", "completion": "{\"entities\": [{\"text\": \"Death\", \"type\": \"Disease\"}, {\"text\": \"gestational trophoblastic disease\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02207", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Results indicate that GSPE preexposure prior to AAP, AMI and DOX, provided near complete protection in terms of serum chemistry changes (ALT, BUN and CPK ), and significantly reduced DNA fragmentation.", "completion": "{\"entities\": [{\"text\": \"GSPE\", \"type\": \"Chemical\"}, {\"text\": \"AAP\", \"type\": \"Chemical\"}, {\"text\": \"AMI\", \"type\": \"Chemical\"}, {\"text\": \"DOX\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01914", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Brain and spinal cord NTE activities were measured in Long - Evans male rats 1 hr post - exposure to various dosages of Mipafox (ip, 1 - 15 mg / kg ). These data were correlated with histologically scored cervical cord damage in a separate group of similarly dosed rats sampled 14 - 21 days post - exposure.", "completion": "{\"entities\": [{\"text\": \"Mipafox\", \"type\": \"Chemical\"}, {\"text\": \"cord damage\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00823", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 1 %), and seven (10 %) patients, respectively.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00678", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In inflamed preparations, the muscarinic receptor antagonism on the phasic component of the electrical field stimulation - evoked contraction was decreased and the pirenzepine and 4-DAMP antagonism on the tonic component was much less efficient than in controls.", "completion": "{\"entities\": [{\"text\": \"pirenzepine\", \"type\": \"Chemical\"}, {\"text\": \"4-DAMP\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00671", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In vitro characterization of parasympathetic and sympathetic responses in cyclophosphamide - induced cystitis in the rat.", "completion": "{\"entities\": [{\"text\": \"cyclophosphamide\", \"type\": \"Chemical\"}, {\"text\": \"cystitis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03553", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: All markers remained stable in controls.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02721", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Moreover, systemic lipopolysaccharide pretreatment (1 mg / kg) attenuated local methamphetamine infusion - produced dopamine and 3,4-dihydroxyphenylacetic acid depletions in the striatum, indicating that the protective effect of lipopolysaccharide is less likely due to interrupted peripheral distribution or metabolism of methamphetamine.", "completion": "{\"entities\": [{\"text\": \"lipopolysaccharide\", \"type\": \"Chemical\"}, {\"text\": \"methamphetamine\", \"type\": \"Chemical\"}, {\"text\": \"dopamine\", \"type\": \"Chemical\"}, {\"text\": \"3,4-dihydroxyphenylacetic acid\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03024", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This group was compared with a control group of 135 patients with ruptured aneurysms and no history of cocaine abuse.", "completion": "{\"entities\": [{\"text\": \"ruptured aneurysms\", \"type\": \"Disease\"}, {\"text\": \"cocaine abuse\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00087", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: administration does not contribute to bladder damage.", "completion": "{\"entities\": [{\"text\": \"bladder damage\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02354", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: L-NAME reduced gentamicin - induced hearing loss", "completion": "{\"entities\": [{\"text\": \"L-NAME\", \"type\": \"Chemical\"}, {\"text\": \"gentamicin\", \"type\": \"Chemical\"}, {\"text\": \"hearing loss\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04061", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In this study, we investigated the therapeutic potential of bone marrow mononuclear cells (BMCs) in a model of epilepsy induced by pilocarpine in rats.", "completion": "{\"entities\": [{\"text\": \"epilepsy\", \"type\": \"Disease\"}, {\"text\": \"pilocarpine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01951", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Seventeen of these had a response or were stable for a median of 20 weeks (range 6 to more than 66 weeks ). The catheterization procedure is safe, with no immediate complication in 111 infusions of BCNU.", "completion": "{\"entities\": [{\"text\": \"BCNU\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01338", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The efficacy of prochlorperazine in the treatment of headache and nausea", "completion": "{\"entities\": [{\"text\": \"prochlorperazine\", \"type\": \"Chemical\"}, {\"text\": \"headache\", \"type\": \"Disease\"}, {\"text\": \"nausea\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00382", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Epidural blood flow during prostaglandin E1 or trimethaphan induced hypotension.", "completion": "{\"entities\": [{\"text\": \"prostaglandin E1\", \"type\": \"Chemical\"}, {\"text\": \"trimethaphan\", \"type\": \"Chemical\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00909", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Renal papillary necrosis (RPN) and a decreased urinary concentrating ability developed during continuous long - term treatment with aspirin and paracetamol in female Fischer 344 rats.", "completion": "{\"entities\": [{\"text\": \"Renal papillary necrosis\", \"type\": \"Disease\"}, {\"text\": \"RPN\", \"type\": \"Disease\"}, {\"text\": \"aspirin\", \"type\": \"Chemical\"}, {\"text\": \"paracetamol\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-03623", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The endothelial ultrastructure was unaffected by D-pen, and no differences in aortic 131I - HSA radioactivity or aorta / serum - ratio were recorded between experimental and control groups 10 minutes after tracer injection, indicating that the permeability of the endothelial barrier to albumin remained unaffected by D-pen treatment.", "completion": "{\"entities\": [{\"text\": \"D-pen\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01710", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: Vasopressor agents are used to correct anesthesia - induced hypotension.", "completion": "{\"entities\": [{\"text\": \"hypotension\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01931", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Cross - sectional echocardiographic screening of newborns exposed to lithium during gestation can provide highly accurate, noninvasive assessment of the presence or absence of lithium - induced cardiac malformations", "completion": "{\"entities\": [{\"text\": \"lithium\", \"type\": \"Chemical\"}, {\"text\": \"cardiac malformations\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00181", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: d .) was prescribed in addition.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-02801", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: RESULTS: All patients (65 +/- 16 yrs; 58% males) finished the examination.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-reassigned-03476", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0 nmol mouse - 1, i.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00004", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Naloxone alone did not affect either blood pressure or heart rate.", "completion": "{\"entities\": [{\"text\": \"Naloxone\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01948", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Twelve patients with Grade III or IV astrocytomas were treated after partial resection of the tumor without prior radiation therapy.", "completion": "{\"entities\": [{\"text\": \"astrocytomas\", \"type\": \"Disease\"}, {\"text\": \"tumor\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03874", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Although tacrolimus was suspected to be the cause of late post - transplant renal acidosis and was replaced by sirolimus, acidosis, and electrolyte imbalance got worse.", "completion": "{\"entities\": [{\"text\": \"tacrolimus\", \"type\": \"Chemical\"}, {\"text\": \"acidosis\", \"type\": \"Disease\"}, {\"text\": \"sirolimus\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03628", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We measured the plasma level of brain natriuretic peptide (BNP) to determine whether BNP might serve as a simple diagnostic indicator of anthracycline - induced cardiotoxicity in patients with acute leukemia treated with a daunorubicin (DNR )- containing regimen.", "completion": "{\"entities\": [{\"text\": \"anthracycline\", \"type\": \"Chemical\"}, {\"text\": \"cardiotoxicity\", \"type\": \"Disease\"}, {\"text\": \"acute leukemia\", \"type\": \"Disease\"}, {\"text\": \"daunorubicin\", \"type\": \"Chemical\"}, {\"text\": \"DNR\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-01064", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Biological features of hepatitis disappeared in all cases after cessation of the incriminated drug, while biliary, viral and immunological searches were negative.", "completion": "{\"entities\": [{\"text\": \"hepatitis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03530", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Evaluation of cardiac troponin I and T levels as markers of myocardial damage in doxorubicin - induced cardiomyopathy rats, and their relationship with echocardiographic and histological findings.", "completion": "{\"entities\": [{\"text\": \"myocardial damage\", \"type\": \"Disease\"}, {\"text\": \"doxorubicin\", \"type\": \"Chemical\"}, {\"text\": \"cardiomyopathy\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-03861", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0012 ). Dexamethasone had no significant effect on the incidence or severity of postoperative nausea and vomiting.", "completion": "{\"entities\": [{\"text\": \"Dexamethasone\", \"type\": \"Chemical\"}, {\"text\": \"postoperative nausea and vomiting\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01193", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Plasma concentration of AVP and transcripts of AVP gene in the PVN and SON were significantly increased in the Li - treated rats compared with controls.", "completion": "{\"entities\": [{\"text\": \"AVP\", \"type\": \"Chemical\"}, {\"text\": \"Li\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01751", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: of fat - free dry weight ). Infusions of calcium chloride sufficient to raise serum calcium concentrations 2 mEq.", "completion": "{\"entities\": [{\"text\": \"calcium\", \"type\": \"Chemical\"}, {\"text\": \"calcium chloride\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04667", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 001 ), with rizatriptan being superior to ergotamine / caffeine within 30 min of dosing.", "completion": "{\"entities\": [{\"text\": \"rizatriptan\", \"type\": \"Chemical\"}, {\"text\": \"ergotamine\", \"type\": \"Chemical\"}, {\"text\": \"caffeine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04114", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 5 mg / dL ), and they were compared to 2 randomly selected controls per case.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01728", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A novel, multiple symptom model of obsessive-compulsive-like behaviors in animals.", "completion": "{\"entities\": [{\"text\": \"obsessive-compulsive-like behaviors\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05154", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This study should be repeated on a larger sample.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01626", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: There is an urgent need to raise awareness about this potentially fatal complication of clozapine use.", "completion": "{\"entities\": [{\"text\": \"clozapine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04464", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Three cases were related to cyclosporine, and 1 case was secondary to both cyclosporine and tacrolimus.", "completion": "{\"entities\": [{\"text\": \"cyclosporine\", \"type\": \"Chemical\"}, {\"text\": \"tacrolimus\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04277", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Midazolam hydrochloride is commonly used for dental or endoscopic procedures.", "completion": "{\"entities\": [{\"text\": \"Midazolam hydrochloride\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00549", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The later enhancement was attenuated after intra - accumbens shell treatment with GR 55562 (1 microg / side ). Our findings indicate that cocaine induced hyperlocomotion is modified by 5 - HT1B receptor ligands microinjected into the accumbens shell, but not core, this modification consisting in inhibitory and facilitatory effects of the 5 - HT1B receptor antagonist (GR 55562) and agonist (CP 93129", "completion": "{\"entities\": [{\"text\": \"GR 55562\", \"type\": \"Chemical\"}, {\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"hyperlocomotion\", \"type\": \"Disease\"}, {\"text\": \"CP 93129\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00098", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The administration of several benzodiazepines, chemically related to clotiazepam, did not interfere with recovery and did not induce any relapse of hepatitis.", "completion": "{\"entities\": [{\"text\": \"benzodiazepines\", \"type\": \"Chemical\"}, {\"text\": \"clotiazepam\", \"type\": \"Chemical\"}, {\"text\": \"hepatitis\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-00915", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Less frequent lithium administration and lower urine volume.", "completion": "{\"entities\": [{\"text\": \"lithium\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02244", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Ifosfamide encephalopathy presenting with asterixis.", "completion": "{\"entities\": [{\"text\": \"Ifosfamide\", \"type\": \"Chemical\"}, {\"text\": \"encephalopathy\", \"type\": \"Disease\"}, {\"text\": \"asterixis\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-01225", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: PG-9 was also able to increase the amount of NGF secreted in vitro by astrocytes in a dose - dependent manner.", "completion": "{\"entities\": [{\"text\": \"PG-9\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01077", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A 61 - year - old man was treated with combination chemotherapy incorporating cisplatinum, etoposide, high - dose 5-fluorouracil (2, 250 mg / m2 / 24 hours) and folinic acid for an inoperable gastric adenocarcinoma.", "completion": "{\"entities\": [{\"text\": \"cisplatinum\", \"type\": \"Chemical\"}, {\"text\": \"etoposide\", \"type\": \"Chemical\"}, {\"text\": \"5-fluorouracil\", \"type\": \"Chemical\"}, {\"text\": \"folinic acid\", \"type\": \"Chemical\"}, {\"text\": \"gastric adenocarcinoma\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-03780", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This report demonstrates for the first time that the pharmacodynamic properties of cyclosporin A", "completion": "{\"entities\": [{\"text\": \"cyclosporin A\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00140", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 001 ), respectively, but no tachycardia and no augmentation of the norepinephrine release rate (up to 0.", "completion": "{\"entities\": [{\"text\": \"tachycardia\", \"type\": \"Disease\"}, {\"text\": \"norepinephrine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03057", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 1 microM ). Phenylephrine infusion increased arterial pressure, arteriolar diameter and clearance of fluorescent dextran by a similar magnitude in both groups.", "completion": "{\"entities\": [{\"text\": \"Phenylephrine\", \"type\": \"Chemical\"}, {\"text\": \"dextran\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02869", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Increased sensitivity of the fusimotor system during acute muscle pain", "completion": "{\"entities\": [{\"text\": \"muscle pain\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00791", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A conjunction analysis of the encode and recall phases of the task revealed ecstasy - specific hyperactivity in bilateral frontal regions, left temporal, right parietal, bilateral temporal, and bilateral occipital brain regions.", "completion": "{\"entities\": [{\"text\": \"ecstasy\", \"type\": \"Chemical\"}, {\"text\": \"hyperactivity\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03094", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 25) blunted the early (< 60 min) free - field locomotor hypoactivity caused by nicotine (0.", "completion": "{\"entities\": [{\"text\": \"locomotor hypoactivity\", \"type\": \"Disease\"}, {\"text\": \"nicotine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02468", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 0024 ). Before the switch, 11.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01826", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Therefore, we studied the hyperemic response to dipyridamole in seven open - chest anesthetized dogs after pretreatment with either pentoxifylline (0, 7.", "completion": "{\"entities\": [{\"text\": \"dipyridamole\", \"type\": \"Chemical\"}, {\"text\": \"pentoxifylline\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-05217", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Test conditions influence the response to a drug challenge in rodents.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00668", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 93 mg / dL (P =. 02 ). Heavy proteinuria was common after the use of SRL as rescue therapy for renal transplantation.", "completion": "{\"entities\": [{\"text\": \"proteinuria\", \"type\": \"Disease\"}, {\"text\": \"SRL\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03866", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Fentanyl did reduce minor intraoperative movement but had no sevoflurane - sparing effect and increased respiratory depression, hypotension and bradycardia.", "completion": "{\"entities\": [{\"text\": \"Fentanyl\", \"type\": \"Chemical\"}, {\"text\": \"sevoflurane\", \"type\": \"Chemical\"}, {\"text\": \"respiratory depression\", \"type\": \"Disease\"}, {\"text\": \"hypotension\", \"type\": \"Disease\"}, {\"text\": \"bradycardia\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-03662", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 2 ), hypoplastic left heart syndrome (AOR = 4.", "completion": "{\"entities\": [{\"text\": \"hypoplastic left heart syndrome\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-03456", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Trial medication was 2.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04326", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Left ventricular filling pressure decreased from 19 +/- 2 to 11 +/- 2 mm Hg (P less than 0.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00479", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: High levels of matrix Gla protein are found at sites of artery calcification in rats treated with vitamin D plus Warfarin, and chemical analysis showed that the protein that accumulated was indeed not gamma-carboxylated.", "completion": "{\"entities\": [{\"text\": \"artery calcification\", \"type\": \"Disease\"}, {\"text\": \"vitamin D\", \"type\": \"Chemical\"}, {\"text\": \"Warfarin\", \"type\": \"Chemical\"}, {\"text\": \"gamma-carboxylated\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01923", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Azathioprine treatment benefited 19 (66 %) out of 29 patients suffering from severe psoriasis.", "completion": "{\"entities\": [{\"text\": \"Azathioprine\", \"type\": \"Chemical\"}, {\"text\": \"psoriasis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-01954", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Blood pressure response to chronic low - dose intrarenal noradrenaline infusion in conscious rats.", "completion": "{\"entities\": [{\"text\": \"noradrenaline\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00005", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In brain membranes from spontaneously hypertensive rats clonidine, 10 (- 8) to 10 (- 5) M, did not influence stereoselective binding of [3H]-naloxone (8 nM ), and naloxone, 10 (- 8) to 10 (- 4) M, did not influence clonidine - suppressible binding of [3H]-dihydroergocryptine (1 nM ). These findings indicate that in spontaneously hypertensive rats the effects of central alpha - adrenoceptor stimulation involve activation of opiate receptors.", "completion": "{\"entities\": [{\"text\": \"hypertensive\", \"type\": \"Disease\"}, {\"text\": \"clonidine\", \"type\": \"Chemical\"}, {\"text\": \"[3H]-naloxone\", \"type\": \"Chemical\"}, {\"text\": \"naloxone\", \"type\": \"Chemical\"}, {\"text\": \"[3H]-dihydroergocryptine\", \"type\": \"Chemical\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-00154", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The relationship of arthritis and sexual dysfunction was investigated among 169 patients with rheumatoid arthritis, osteoarthritis and spondyloarthropathy, 130 of whom were pair - matched to controls.", "completion": "{\"entities\": [{\"text\": \"arthritis\", \"type\": \"Disease\"}, {\"text\": \"sexual dysfunction\", \"type\": \"Disease\"}, {\"text\": \"rheumatoid arthritis\", \"type\": \"Disease\"}, {\"text\": \"osteoarthritis\", \"type\": \"Disease\"}, {\"text\": \"spondyloarthropathy\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-00611", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: We report the case of a woman complaining of dysphonia while she was treated by acitretin.", "completion": "{\"entities\": [{\"text\": \"dysphonia\", \"type\": \"Disease\"}, {\"text\": \"acitretin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03558", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSIONS: Among markers of ischemic injury after DOX in rats, cTnT showed the greatest ability to detect myocardial damage assessed by echocardiographic detection and histological changes.", "completion": "{\"entities\": [{\"text\": \"ischemic injury\", \"type\": \"Disease\"}, {\"text\": \"DOX\", \"type\": \"Chemical\"}, {\"text\": \"myocardial damage\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02674", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 01 ). Allopurinol decreased serum urate from 76 +/- 5 to 30 +/- 3 micromol / L (P < 0.", "completion": "{\"entities\": [{\"text\": \"Allopurinol\", \"type\": \"Chemical\"}, {\"text\": \"urate\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00978", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Analysis of the respiratory changes in the arterial pressure waveform enabled differentiation between the two groups.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03693", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Improved outcomes among patients with head and neck carcinomas require investigations of new drugs for induction therapy.", "completion": "{\"entities\": [{\"text\": \"head and neck carcinomas\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00979", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The SPV during hypotension was 15.", "completion": "{\"entities\": [{\"text\": \"hypotension\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-05186", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Until then, clinicians need to be aware of this possible complication associated with zonisamide", "completion": "{\"entities\": [{\"text\": \"zonisamide\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00639", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Laboratory measurement of pre - procedure serum calcium", "completion": "{\"entities\": [{\"text\": \"calcium\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00274", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Dothiepin also produced fewer CNS and cardiovascular effects.", "completion": "{\"entities\": [{\"text\": \"Dothiepin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02653", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In Group 1 the rats were trained under the influence of pentobarbital to run to the same shelf as in the normal state.", "completion": "{\"entities\": [{\"text\": \"pentobarbital\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04706", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Common features included tachycardia, drowsiness, hallucinations and convulsions.", "completion": "{\"entities\": [{\"text\": \"tachycardia\", \"type\": \"Disease\"}, {\"text\": \"hallucinations\", \"type\": \"Disease\"}, {\"text\": \"convulsions\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02094", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A previously healthy child who developed acute, severe, rapidly progressive vanishing bile duct syndrome shortly after Stevens-Johnson syndrome is described; this was temporally associated with ibuprofen use.", "completion": "{\"entities\": [{\"text\": \"vanishing bile duct syndrome\", \"type\": \"Disease\"}, {\"text\": \"Stevens-Johnson syndrome\", \"type\": \"Disease\"}, {\"text\": \"ibuprofen\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02902", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: This drug occasionally has been associated with acute interstitial nephritis in native kidneys.", "completion": "{\"entities\": [{\"text\": \"interstitial nephritis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-02318", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The blood flow responses seem to be mediated by the release of acetylcholine and VIP within the meninges.", "completion": "{\"entities\": [{\"text\": \"acetylcholine\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00759", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Severe gastric ulcers accompanied with increased ulcerogenic factors, including gastric acid back - diffusion, histamine release, LPO generation and luminal hemoglobin content were also observed in these rats.", "completion": "{\"entities\": [{\"text\": \"ulcers\", \"type\": \"Disease\"}, {\"text\": \"histamine\", \"type\": \"Chemical\"}, {\"text\": \"luminal\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-05072", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: d - 1 given for 4 weeks, elevated blood pressure from 102 +/- 13 to 152 +/- 15 mm Hg and increased the synthesis of ET - 1 and the levels of ET - 1 mRNA in the mesenteric artery (240% and 230 %, respectively ). Little change was observed in the expression of ECE - 1 mRNA and CNP mRNA.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03753", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Phase II study of the amsacrine analogue CI-921 (NSC 343499) in non-small cell lung cancer.", "completion": "{\"entities\": [{\"text\": \"amsacrine\", \"type\": \"Chemical\"}, {\"text\": \"CI-921\", \"type\": \"Chemical\"}, {\"text\": \"NSC 343499\", \"type\": \"Chemical\"}, {\"text\": \"non-small cell lung cancer\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02551", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Massive proteinuria and acute renal failure after oral bisphosphonate (alendronate) administration in a patient with focal segmental glomerulosclerosis.", "completion": "{\"entities\": [{\"text\": \"proteinuria\", \"type\": \"Disease\"}, {\"text\": \"acute renal failure\", \"type\": \"Disease\"}, {\"text\": \"bisphosphonate\", \"type\": \"Chemical\"}, {\"text\": \"alendronate\", \"type\": \"Chemical\"}, {\"text\": \"focal segmental glomerulosclerosis\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-04210", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Chemical analysis of gall stones retrieved at cholecystectomy from two patients, showed that they contained 71% and 87% cholesterol by weight.", "completion": "{\"entities\": [{\"text\": \"gall stones\", \"type\": \"Disease\"}, {\"text\": \"cholesterol\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00774", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Mitochondrial injury may be involved in the progression of heart failure caused by adriamycin", "completion": "{\"entities\": [{\"text\": \"heart failure\", \"type\": \"Disease\"}, {\"text\": \"adriamycin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00043", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Eight Crohn's disease patients were included.", "completion": "{\"entities\": [{\"text\": \"Crohn's disease\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04582", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: No enhancement by phenobarbital of the hepatocarcinogenicity of a choline - devoid diet in the rat.", "completion": "{\"entities\": [{\"text\": \"phenobarbital\", \"type\": \"Chemical\"}, {\"text\": \"choline\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-02703", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Dental patients abusing methamphetamine can present with poor oral hygiene, xerostomia, rampant caries (\" meth mouth \"), and excessive tooth wear.", "completion": "{\"entities\": [{\"text\": \"methamphetamine\", \"type\": \"Chemical\"}, {\"text\": \"xerostomia\", \"type\": \"Disease\"}, {\"text\": \"caries\", \"type\": \"Disease\"}, {\"text\": \"meth mouth\", \"type\": \"Disease\"}, {\"text\": \"tooth wear\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-02127", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Furthermore, it was observed that TAM inhibits the peroxidation of human erythrocytes induced by AAPH, thus ruling out TAM - induced cell oxidative stress.", "completion": "{\"entities\": [{\"text\": \"TAM\", \"type\": \"Chemical\"}, {\"text\": \"AAPH\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04758", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Although clinical experience with omeprazole is still limited, many controlled studies have established the short - term safety of this drug.", "completion": "{\"entities\": [{\"text\": \"omeprazole\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01794", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Reactions consisted mainly of seizures, acute psychoses, anxiety neurosis, and major disturbances of sleep-wake rhythm.", "completion": "{\"entities\": [{\"text\": \"seizures\", \"type\": \"Disease\"}, {\"text\": \"psychoses\", \"type\": \"Disease\"}, {\"text\": \"anxiety neurosis\", \"type\": \"Disease\"}, {\"text\": \"disturbances of sleep-wake rhythm\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04052", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In group C, AKBR showed a significant decrease at 120 min (- 40 %) and at 180 min (- 49 %) after the start of hypotension and at 60 min (- 32 %) after recovery of normotension, and SGOT, SGPT, LDH and total bilirubin showed significant increases after operation.", "completion": "{\"entities\": [{\"text\": \"hypotension\", \"type\": \"Disease\"}, {\"text\": \"bilirubin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-03002", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: An accurate autopsy revealed most organs with diffuse petechial haemorrhages.", "completion": "{\"entities\": [{\"text\": \"haemorrhages\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04269", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: However, only secretory granules showed the positive reaction products for prolactin 6 h after bromocriptine treatment of the adenoma cells.", "completion": "{\"entities\": [{\"text\": \"bromocriptine\", \"type\": \"Chemical\"}, {\"text\": \"adenoma\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00277", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Behavioral effects of diazepam and propranolol in patients with panic disorder and agoraphobia.", "completion": "{\"entities\": [{\"text\": \"diazepam\", \"type\": \"Chemical\"}, {\"text\": \"propranolol\", \"type\": \"Chemical\"}, {\"text\": \"panic disorder\", \"type\": \"Disease\"}, {\"text\": \"agoraphobia\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-02197", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Ultimately, an arteriography showed a 70 - 80% renal artery stenosis.", "completion": "{\"entities\": [{\"text\": \"renal artery stenosis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01743", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Effects of acetylsalicylic acid, dipyridamole, and hydrocortisone on epinephrine - induced myocardial injury in dogs.", "completion": "{\"entities\": [{\"text\": \"acetylsalicylic acid\", \"type\": \"Chemical\"}, {\"text\": \"dipyridamole\", \"type\": \"Chemical\"}, {\"text\": \"hydrocortisone\", \"type\": \"Chemical\"}, {\"text\": \"epinephrine\", \"type\": \"Chemical\"}, {\"text\": \"myocardial injury\", \"type\": \"Disease\"}]}", "n_entities": 5}
{"ref": "bc5cdr-train-00324", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Streptomycin sulfate (300 mg / kg s.", "completion": "{\"entities\": [{\"text\": \"Streptomycin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00546", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Such attenuation was not found in animals which had been injected with GR 55562 into the accumbens core.", "completion": "{\"entities\": [{\"text\": \"GR 55562\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-00576", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: The aim of the present study was to investigate changes in the plasma calcitonin gene-related peptide (CGRP) concentration and platelet serotonin (5-hydroxytriptamine, 5-HT) content during the immediate headache and the delayed genuine migraine attack provoked by nitroglycerin.", "completion": "{\"entities\": [{\"text\": \"calcitonin gene-related peptide\", \"type\": \"Chemical\"}, {\"text\": \"CGRP\", \"type\": \"Chemical\"}, {\"text\": \"serotonin\", \"type\": \"Chemical\"}, {\"text\": \"5-hydroxytriptamine\", \"type\": \"Chemical\"}, {\"text\": \"5-HT\", \"type\": \"Chemical\"}, {\"text\": \"headache\", \"type\": \"Disease\"}, {\"text\": \"migraine\", \"type\": \"Disease\"}, {\"text\": \"nitroglycerin\", \"type\": \"Chemical\"}]}", "n_entities": 8}
{"ref": "bc5cdr-train-04840", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Therefore, the present study was carried out to investigate the effect of chronic curcumin administration on phenobarbitone - and carbamazepine - induced cognitive impairment and oxidative stress in rats.", "completion": "{\"entities\": [{\"text\": \"curcumin\", \"type\": \"Chemical\"}, {\"text\": \"phenobarbitone\", \"type\": \"Chemical\"}, {\"text\": \"carbamazepine\", \"type\": \"Chemical\"}, {\"text\": \"cognitive impairment\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-00132", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: infusions of human alpha - atrial natriuretic factor.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-01442", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: SDRR was reduced only by alpha-methyldopa.", "completion": "{\"entities\": [{\"text\": \"alpha-methyldopa\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04173", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Details of spinal puncture, extension and regression of spinal block, and the times to reach discharge criteria were noted.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-03639", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: DESIGN, SETTING, AND PARTICIPANTS: Population - based, multisite, case - control study of women who had pregnancies affected by 1 of more than 30 eligible major birth defects identified via birth defect surveillance programs in 10 states (n = 13 155) and control women randomly selected from the same geographical regions (n = 4941 ). MAIN EXPOSURE: Reported maternal use of antibacterials (1 month before pregnancy through the end of the first trimester ). MAIN OUTCOME MEASURE: Odds ratios (ORs) measuring the association between antibacterial use and selected birth defects adjusted for potential confounders.", "completion": "{\"entities\": [{\"text\": \"birth defect\", \"type\": \"Disease\"}, {\"text\": \"birth defects\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00381", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In summary, the chick embryo provides a reliable and simple experimental animal model of coniine - induced arthrogryposis", "completion": "{\"entities\": [{\"text\": \"coniine\", \"type\": \"Chemical\"}, {\"text\": \"arthrogryposis\", \"type\": \"Disease\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04941", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Determination was repeated in case of abnormal first results.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-00828", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In multivariate analysis, three factors independently predicted mortality: serum bilirubin (> or = 10.", "completion": "{\"entities\": [{\"text\": \"bilirubin\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01291", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: To further validate the hypothesis that the anti - cocaine effects of the novel ligands involved antagonism of sigma receptors, an antisense oligodeoxynucleotide against sigma1 receptors was also shown to significantly attenuate the convulsive and locomotor stimulatory effects of cocaine.", "completion": "{\"entities\": [{\"text\": \"cocaine\", \"type\": \"Chemical\"}, {\"text\": \"oligodeoxynucleotide\", \"type\": \"Chemical\"}, {\"text\": \"convulsive\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-02795", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Safety of transesophageal echocardiography in adults: study in a multidisciplinary hospital.", "completion": "{\"entities\": []}", "n_entities": 0}
{"ref": "bc5cdr-train-04107", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: CONCLUSION: Here we report a case of acute hepatitis probably associated with the administration of telithromycin", "completion": "{\"entities\": [{\"text\": \"hepatitis\", \"type\": \"Disease\"}, {\"text\": \"telithromycin\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-00858", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Eighty - nine new referral hypertensive out - patients and 46 new referral non - hypertensive chronically physically ill out - patients completed a mood rating scale at regular intervals for one year.", "completion": "{\"entities\": [{\"text\": \"hypertensive\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01700", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: As a result, there is a growing interest in the development of pharmacological agents with potential antipsychotic properties that enhance the activity of the glutamatergic system via a modulation of the NMDA receptor.", "completion": "{\"entities\": [{\"text\": \"NMDA\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04373", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: HS diet for 4 wk caused a progressive increase in BP, protein and albumin excretion, and glomerular sclerosis in male DS rats, which were attenuated by castration.", "completion": "{\"entities\": [{\"text\": \"glomerular sclerosis\", \"type\": \"Disease\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-04697", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: A week later, fulminant drug-induced hepatitis, associated with the presence of anti - nuclear autoantibodies (but not with other markers of autoimmunity ), and accompanied by multi-organ failure and sepsis, supervened.", "completion": "{\"entities\": [{\"text\": \"drug-induced hepatitis\", \"type\": \"Disease\"}, {\"text\": \"autoimmunity\", \"type\": \"Disease\"}, {\"text\": \"multi-organ failure\", \"type\": \"Disease\"}, {\"text\": \"sepsis\", \"type\": \"Disease\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-01686", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Administration of green tea (100 mg / kg / day, p.", "completion": "{\"entities\": [{\"text\": \"green tea\", \"type\": \"Chemical\"}]}", "n_entities": 1}
{"ref": "bc5cdr-train-01740", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: She was treated with heparin, dipyridamole and hemodialysis; and after more than three months, her urinary output rose above 500 ml; and six months after the onset of anuria, dialysis treatment was stopped.", "completion": "{\"entities\": [{\"text\": \"heparin\", \"type\": \"Chemical\"}, {\"text\": \"dipyridamole\", \"type\": \"Chemical\"}, {\"text\": \"anuria\", \"type\": \"Disease\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04659", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: 2% of patients who preferred ergotamine / caffeine.", "completion": "{\"entities\": [{\"text\": \"ergotamine\", \"type\": \"Chemical\"}, {\"text\": \"caffeine\", \"type\": \"Chemical\"}]}", "n_entities": 2}
{"ref": "bc5cdr-train-04162", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: BACKGROUND: Recent evidence suggests that transient neurologic symptoms (TNSs) frequently follow lidocaine spinal anesthesia but are infrequent with bupivacaine.", "completion": "{\"entities\": [{\"text\": \"transient neurologic symptoms\", \"type\": \"Disease\"}, {\"text\": \"TNSs\", \"type\": \"Disease\"}, {\"text\": \"lidocaine\", \"type\": \"Chemical\"}, {\"text\": \"bupivacaine\", \"type\": \"Chemical\"}]}", "n_entities": 4}
{"ref": "bc5cdr-train-04284", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: Effect of L-alpha-glyceryl-phosphorylcholine on amnesia caused by scopolamine.", "completion": "{\"entities\": [{\"text\": \"L-alpha-glyceryl-phosphorylcholine\", \"type\": \"Chemical\"}, {\"text\": \"amnesia\", \"type\": \"Disease\"}, {\"text\": \"scopolamine\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-05158", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: In the present study, the authors induced orofacial dyskinesia by acute reserpine and subchronic haloperidol administration to rats.", "completion": "{\"entities\": [{\"text\": \"orofacial dyskinesia\", \"type\": \"Disease\"}, {\"text\": \"reserpine\", \"type\": \"Chemical\"}, {\"text\": \"haloperidol\", \"type\": \"Chemical\"}]}", "n_entities": 3}
{"ref": "bc5cdr-train-04166", "prompt": "Extract every chemical and disease entity from the biomedical text below.\nReturn only JSON in this form, with no other text:\n{\"entities\": [{\"text\": \"...\", \"type\": \"Chemical\"}]}\nUse \"Chemical\" or \"Disease\" for the type. If the text truly contains no chemical or disease entities, return {\"entities\": []}.\n\nText: METHODS: Ninety patients classified as American Society of Anesthesiologists physical status I or II who were scheduled for short gynecologic procedures under spinal anesthesia were randomly allocated to receive 2.", "completion": "{\"entities\": []}", "n_entities": 0}