{
  "frozen_cache": {
    "identity_axis_sha256": "c6765f386d066ec731442316c88395acee2ab6fbef009a5a2fd59696b738b6fd",
    "path": "inputs/responses_ab.npy",
    "sha256": "bb48bae7f864c66b242a77cef064ff967b418d22bb11416630548f6a6d094a94",
    "shape": [
      2,
      9205,
      8248
    ]
  },
  "gate_decision": "PASS: `view_specific_batch_weighted` reproduces every sampled FIT/SELECT delta element at atol=1e-05, rtol=1e-05. Gate 2 may materialize quarantined endpoint assets using this exact recipe, then must validate the invariant on all identities before release.",
  "pairing_statement": "Each endpoint candidate has a deterministic perturbation pseudobulk goal in each A/B batch-disjoint view. The source candidate is a deterministic weighted mixture of batch-specific control pseudobulks; this audit tests whether its weights are pooled across views or restricted to the endpoint view.",
  "raw": {
    "aggregation": "per-cell library-size 10000 then log1p; mean pseudobulk",
    "gene_order_exact_match": true,
    "path": "PUBLIC_SOURCE/ReplogleWeissman2022_K562_gwps.h5ad",
    "sha256": "d3269d9c863d96555eba768b42ab330cc1b57493cd33b4ac8fe7fbab8278f104",
    "shape": [
      1989578,
      8248
    ]
  },
  "sample": {
    "count": 64,
    "identities": [
      "OSBPL8",
      "SSX4",
      "ZNF576",
      "NFE2L1",
      "NRIP1",
      "SEC16A",
      "CSNK1A1",
      "CRADD",
      "SYVN1",
      "SPATA2L",
      "DNAJC30",
      "UPRT",
      "TLE3",
      "ARGFX",
      "IFT80",
      "ZSCAN23",
      "MLF2",
      "LARP4",
      "HIST1H2BL",
      "GEMIN7",
      "TKT",
      "ERVW-1",
      "C14orf178",
      "ZNF384",
      "NOTUM",
      "GAA",
      "BTBD10",
      "COX16",
      "MAP1LC3B",
      "ATF6",
      "PPP2R3B",
      "EBAG9",
      "SRP72",
      "EIF2B5",
      "L3HYPDH",
      "OTP",
      "OTX2",
      "ENTR1",
      "DCPS",
      "TICRR",
      "TAX1BP3",
      "COCH",
      "ZFPL1",
      "GNA13",
      "ZNF442",
      "VENTX",
      "ZBTB40",
      "STX6",
      "SMG6",
      "MTMR4",
      "RELA",
      "BBC3",
      "MOK",
      "CTPS2",
      "PSMC1",
      "ZNF48",
      "ATP1A1",
      "RAP2B",
      "DARS",
      "PIN4",
      "MIF",
      "ARL6IP1",
      "TASOR2",
      "CWC15"
    ],
    "roles": [
      "G_fit",
      "G_select"
    ],
    "selection": "SHA-256 deterministic identity order with salt SOURCE_GOAL_ASSET_RESOLUTION_V1|20260916"
  },
  "sampled_cache_recipe_comparison": {
    "all_batch_weighted": {
      "A": {
        "all_close": false,
        "fraction_close": 0.002911690712900097,
        "max_abs_error": 0.07813365560047059,
        "mean_abs_error": 0.0030257416010429335
      },
      "B": {
        "all_close": false,
        "fraction_close": 0.002907901915615907,
        "max_abs_error": 0.09024386034321341,
        "mean_abs_error": 0.003004935907370192
      }
    },
    "view_specific_batch_weighted": {
      "A": {
        "all_close": true,
        "fraction_close": 1.0,
        "max_abs_error": 1.4648724722121642e-06,
        "mean_abs_error": 9.106084045687916e-09
      },
      "B": {
        "all_close": true,
        "fraction_close": 1.0,
        "max_abs_error": 1.4948276128023963e-06,
        "mean_abs_error": 8.249161447296022e-09
      }
    }
  },
  "schema": "SOURCE_GOAL_ASSET_RESOLUTION_V1_GATE_1",
  "source_diversity": {
    "all_batch_weighted_shared_across_views": {
      "control_mean_matrix_rank": 267,
      "coordinate_variance_mean": 1.4186932821180593e-05,
      "distinct_control_mixture_profile_fraction": 1.0,
      "distinct_control_mixture_profiles": 9205,
      "distinct_source_expression_profile_fraction": 1.0,
      "distinct_source_expression_profiles_float32": 9205,
      "max_perturbations_per_control_mixture": 1,
      "queries": 9205,
      "sample_pair_count": 10000,
      "sample_pair_max_l2_distance": 1.3801618177203594,
      "sample_pair_mean_l2_distance": 0.4570262069036828,
      "sample_pair_median_l2_distance": 0.42392650150797745,
      "source_profile_identity_proven": true
    },
    "view_A_batch_weighted": {
      "control_mean_matrix_rank": 267,
      "coordinate_variance_mean": 2.707875577707947e-05,
      "distinct_control_mixture_profile_fraction": 1.0,
      "distinct_control_mixture_profiles": 9205,
      "distinct_source_expression_profile_fraction": 1.0,
      "distinct_source_expression_profiles_float32": 9205,
      "max_perturbations_per_control_mixture": 1,
      "queries": 9205,
      "sample_pair_count": 10000,
      "sample_pair_max_l2_distance": 2.3858092804354647,
      "sample_pair_mean_l2_distance": 0.6300420630208424,
      "sample_pair_median_l2_distance": 0.5824798516784221,
      "source_profile_identity_proven": true
    },
    "view_B_batch_weighted": {
      "control_mean_matrix_rank": 267,
      "coordinate_variance_mean": 2.9616065717047468e-05,
      "distinct_control_mixture_profile_fraction": 1.0,
      "distinct_control_mixture_profiles": 9205,
      "distinct_source_expression_profile_fraction": 1.0,
      "distinct_source_expression_profiles_float32": 9205,
      "max_perturbations_per_control_mixture": 1,
      "queries": 9205,
      "sample_pair_count": 9998,
      "sample_pair_max_l2_distance": 2.2753692170298243,
      "sample_pair_mean_l2_distance": 0.6546830657966001,
      "sample_pair_median_l2_distance": 0.6043989240791572,
      "source_profile_identity_proven": true
    }
  },
  "status": "GATE_1_PASS_PAIRING_SEMANTICS_RESOLVED",
  "tolerance": {
    "atol": 1e-05,
    "rtol": 1e-05
  }
}