text stringlengths 14 164 |
|---|
Cc1nn(C2(C#N)CC2)cc1Nc1nc(C2CC2)c(-c2cncc3c2ncn3C)nc1C(N)=O |
CC(C)(C)OC(=O)NNCCN(C(=O)OC(C)(C)C)c1cccc2c1OC(C)(c1ccc(Cl)cc1F)O2 |
Cn1c(=O)[nH]c2cccc([C@@H]3CCN(C(=O)OC(C)(C)C)C[C@H]3F)c21 |
CCOC(=O)/C=C/C[C@@H](CNC(=O)OCc1ccccc1)[C@@H](C)NC(=O)OC(C)(C)C |
O=P1([S-])OCC2OC3[C@H](F)[C@@H]2OP(=O)([S-])OC[C@H]2O[C@H]([C@H](F)[C@@H]2O1)n1cnc2c(ncnc21)NC/C=C/CCc1ncnc2c1ncn23 |
Cc1c(C#N)cccc1[C@@H](C)Nc1nncc2cnc(CCl)cc12 |
CNC(=O)COc1cc2cc(Nc3nc(N(C)C)ncc3Cl)ccc2n(CCOc2ccc3c(c2)C(=O)N(C2CCC(=O)NC2=O)C3=O)c1=O |
Cc1c(F)ccc2[nH]c(=O)c(C(F)(F)C(=O)NC(C)c3ncc(C#N)cn3)c(C#N)c12 |
CSc1nc2c3c(c(Cl)c(Br)c(F)c3n1)CCC[C@@H]1[C@@H]3CC[C@H](CN21)N3C(=O)OC(C)(C)C |
CC(C)(C(=O)NCc1cc(Cl)c(C2CCC(=O)NC2=O)c(Cl)c1)c1ccc2[nH]ccc2c1 |
Cc1c(N)cncc1-c1cc2cc(NC(=O)CCN)ncc2c(N)c1F |
Cc1nc(C)c(Cc2cc3c(cc2Cl)[C@@](C#CC2CC2)(C(F)(F)F)NC(=O)N3)c(=O)[nH]1 |
COc1cc(C(=O)N2C[C@H]3CC[C@@H]2[C@@H]3N)cc2nc3n(c12)Cc1cccc(c1)/C=C\CCCCn1c-3cc2cccnc21 |
[2H]C1([2H])Oc2ccc(OC3CCN(c4nc5c(c(C)c4C)C(=O)NC5)CC3)cc2OC1([2H])[2H] |
CN(C)Cc1nc(Nc2ccc(-c3cnc4cc(F)ccn34)c3c2C(=O)NC3)ccc1C1(C)CCCO1 |
CCc1c(N2CCN(C(=O)c3ncnc(C)c3O)CC2)c(=O)c2nc(C3CC3)cnc2n1CC(=O)Nc1ccc(C(F)(F)F)cc1Cl |
Cc1nnc(-c2c(C3CC3c3ccc(F)cc3)nc(CC(C)C)c(C(N)=O)c2-c2ccc(C(=O)NCc3ccc(F)c(F)c3)s2)o1 |
CN1C(=O)C(NC(=O)C2=NN=C(Cc3ccccc3)C2)Cn2ccc3ccnc1c32 |
COC(=O)C1=C(C(F)F)NC2=C(C(=O)OC2)C1c1cncc(F)c1C(C)F |
CC(C)(C)OC(=O)c1cc(OP(=O)(OC(C)(C)C)OC(C)(C)C)c(C(C)(C)CC(=O)O)c(C(=O)OC(C)(C)C)c1 |
Cc1c(C#N)cccc1[C@@H](C)Nc1nnc(N2CC[C@@H](N)C2)c2cnc(N3C[C@H]4C[C@@H]3CO4)cc12 |
C[C@@H](CC(F)Cn1ccc2cc(-c3ncc(C(F)(F)F)cn3)c(F)cc2c1=O)Nc1cn[nH]c(=O)c1C(F)(F)F |
CN(C)C(=O)c1cc2cnc(N[C@@H]3CCOC[C@H]3O)nc2n1-c1ccc2c(c1)C(F)(F)CCC2N(C)C |
CCCn1nc(C)c(O)c1-c1nc(-c2nc(C(N)=O)n3cc(C)ncc23)n(C)n1 |
C[C@H]1CC2(C[C@@H](c3cn(C)nn3)N1)OC(C(N)=O)c1ccc(Cl)cc12 |
[2H]C([2H])([2H])N(Cc1ccc(-c2[nH]c3ncc4c(c3c2-c2ccc3c(c2)CC(C)(C)O3)n([C@@H]2CC[C@@H](NC(=O)OC)C2)c(=O)n4C([2H])([2H])[2H])cc1)C([2H])([2H])[2H] |
CC[C@@H]1CN(Cc2cc(C(CC(=O)O)c3ccc4c(nnn4C)c3C)cc3ccsc23)S(=O)(=O)c2cc(Cl)cnc2O1 |
COc1ccc2c3c1CC=C3CCN2C1CCc2cc(NC(=O)C(F)(F)F)sc2C1 |
CC(C)Oc1ccc2[nH]nc(-c3cc(N4CCN(CCN5CC(OCCOc6ccc7c(c6)C(=O)N(C6CCC(=O)NC6=O)C7=O)C5)[C@@H](C)C4)ncn3)c2c1 |
CCN(C)S(=O)(=O)Nc1ccc(F)c(Oc2ccc3ncn([C@H]4COC5(CCC(S(=O)(=O)CC6(O)CCN(c7cc8c(cc7F)c(N7CCC(=O)NC7=O)nn8C)CC6)CC5)C4)c(=O)c3c2)c1C#N |
Nc1ncccc1-c1nc2ccc(-c3ccccc3)nc2n1-c1ccc(CN2CCC(c3ccc(O)c(C=O)c3)CC2)cc1 |
N=S(=O)(NC(=O)Nc1c2c(cc3c1CCC3)CCC2)c1cnn2c1CCOCC2 |
Nc1cc(C(F)(F)F)c2nc1-c1nnc(o1)[C@@](O)(C(F)(F)F)CC(F)(F)CCCCC2=O |
Cc1ccc(Nc2cnc3c(c2)ncn3-c2cc(F)c(C(C)O)c(-n3nc(C#N)cc3C)c2)nn1 |
O=C(N[C@H]1CCOc2ccccc21)c1cnc2c(-c3cc(F)cc(F)c3F)c(F)ccc2c1C1CC(F)C1 |
Cc1cc2c(CO)c3c(c(C)c2c2c1C1OC4(CN=[N+]=[N-])OC1[C@@](CO)(O2)[C@@]4(O)CBr)C(=O)CCC3 |
Clc1ccc(-c2c(-c3ccccc3Cl)nn3c(Cl)cc(Cl)nc23)cc1 |
C[C@H](NC(=O)CN1C(=O)Nc2ccc(C#N)nc2C12CC2)c1ncc(F)cc1F |
CC(C)n1nccc1C(=O)N[C@H](C(=O)Nc1ccc2c(c1)OC(CN1C[C@@H](C(F)(F)F)NC1=O)C2)C(C1CC1)C1CC1 |
COc1cc2ncc(-c3cncc(N[C@H]4CNCC[C@@H]4F)n3)n2nc1C(C)(O)C(F)(F)F |
Cc1cccc2cc(O)cc(Oc3nc4c(N5CC6CCC(C5)N6)nc(OCC56CCCN5CCC6)nc4s3)c12 |
Cn1cc(C2CCC3OC4(CC(Oc5cc(C#N)ncn5)C4)C(=O)N32)cn1 |
CO[C@@H]1COCC[C@@H]1N[C@@H]1CC[C@@](C(=O)N2Cc3cc(C(F)(F)F)cnc3[C@H](N)C2)(C(C)C)C1 |
N#Cc1c(NS(=O)(=O)N2CC[C@@H](F)C2)ccc(F)c1Oc1ccc2ncn(-c3ccc(N4CCNCC4)cc3)c(=O)c2c1 |
COCC1c2ccc(C3CC3)cc2CN1C(=O)Nc1ccc2c(c1)CN(C1CCC(=O)NC1=O)C2=O |
CCc1cc(NC(=O)C(=O)N2C[C@@H](C)CC[C@@H]2c2ccc3sc(C4CC5CC(F)(F)CC(C4)N5C)nc3c2)cnc1N |
CS(=O)(=O)CCn1cc(CN2CCC3(CC2)OCC(O)c2cc(Cl)sc23)cn1 |
CC1(C)Oc2ncc(-c3nc(-c4ncc(Cl)s4)no3)cc2C[C@@H]1O |
C[C@@H]([C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@@](C)(O)CC[C@]4(C)[C@H]3CC[C@]12C)[C@@H](O)CCc1ccccc1 |
COc1c([C@H]2[C@H](C(=O)Nc3ccnc(C(C)=O)c3)O[C@@](C)(C(F)(F)F)[C@H]2C)ccc(F)c1F |
COC[C@@H]1CN(Cc2cc(F)c3nc(C45CCC(C(C)(C)O)(CC4)CC5)ccc3c2)C[C@H]1Oc1ccc2c(c1)CN([C@H]1CCC(=O)NC1=O)C2=O |
CO[C@@H]1[C@H](OP(NN(C(C)C)C(C)C)OCCC#N)[C@@H](OCP(=O)(OC)OC)O[C@H]1n1ccc(=O)[nH]c1=O |
NS(=O)(=O)c1ccc(Cc2c(-c3ccc(F)c(C#CC4CC4)c3)nn(-c3nc(C(=O)O)co3)c2CC2CC2)cc1F |
O=C1CCCC(C(F)F)N1c1ccc(Br)cc1 |
CCC(=O)C(C(=O)c1sc(-c2ccnc(OC)c2)nc1N(Cc1ccc(OC)cc1)Cc1ccc(OC)cc1)N1CCN(C(=O)OC(C)(C)C)CC1 |
CC(C)n1nccc1C(=O)N[C@H](c1cn2ncc(CN3CC4(CC(F)(F)C4)NC3=O)cc2n1)C1CCC(F)(F)CC1 |
C[C@H]1[C@@H](c2ccc(F)c(F)c2OCCO)[C@H](C(=O)Nc2ccnc(C(N)=O)c2)O[C@@]1(C)C(F)(F)F |
COC(=O)Cn1cc(N(CCCCCCCCCCCCCCN)C(=O)[C@H]2CCCN(c3cncc4ccccc34)C2)ccc1=O |
CCP(=O)(CC)c1nc(N)c2[nH]c(=O)n(Cc3ccc(NCCN(C)C)nc3)c2n1 |
CC1(O)COCC1COc1nc(N2CC3CCC(C2)N3)c2cc(C(F)(F)F)c(-c3ccc(F)c4sc(N)c(C#N)c34)c(F)c2n1 |
C=CC(=O)N1CCN(c2cc3cnc(N)nc3n(-c3cccc(O)c3)c2=O)c2cccc(C)c21 |
COC(=O)N[C@H](C(=O)N1C[C@H]2[C@@H]([C@H]1C(=O)N[C@@H](CCC(C)(F)F)C(=O)C(=O)NC1CC1)C2(C)C)C(C)(C)C |
C=CC(=O)N1CCc2nc(-c3nc(-c4ccc5c(c4)CCNC5)c4ccsc4c3-c3ccc(F)cc3OCCOC)sc2C1 |
[2H]C1([2H])Cc2ncc(Nc3ccncc3F)cc2C([2H])([2H])N1c1nnc(C#N)cc1C |
COc1ccccc1-c1cc(C)ncc1C(=O)Nc1nc2c(s1)C(=O)N(C1CC1)C2 |
CC(C)(C)c1nnc(-c2cc3c(cc2F)C(F)(F)CC(N)C(=O)N3Cc2ccc(OC(F)(F)F)cc2)o1 |
CCS(=O)(=O)NC[C@@H]1[C@H](F)CN1C(=O)[C@@H]1C[C@@]1(F)c1ccc(F)cc1-c1c(F)cccc1F |
O=C(NCc1ccccc1)OCc1ccc(O/C=C/B(O)O)cc1 |
CO[C@@H](C)c1ncc(N2CCN(C)CC2)cc1-c1c2c3cc(c(F)cc3n1CC(F)(F)F)-c1csc(n1)C[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC[C@H](N1)C(=O)OCC(C)(C)C2 |
O=C(O)c1ccc2c(c1)CCCC(c1cccc3c1CCCO3)=C2c1ccc(C=C2CN(CCCF)C2)cc1 |
COC(=O)c1ccc2c(c1)CCC(C)C(c1cccc(Cl)c1)=C2c1cccc(O[C@@H]2CCN(CCCF)C2)c1 |
C=CC(=O)Nc1ccccc1-c1c(CC)n(CC(=O)Nc2ccc(C(F)(F)F)cc2)c2nc(C)c(-c3ccccc3)n2c1=O |
C[C@@H]1CN(C(=O)C(=O)Nc2cnc(N)c3cn[nH]c23)[C@@H](c2ccccc2)CN1C1(C)CC1 |
CCCCN(CCO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)c1nc(NC(=O)OC)nc2cn(Cc3ccc(CO)c4c3OCCC4)nc12 |
CC(C)(C)[S@@](=O)N[C@@H]1c2cnc(CO)cc2CC12CCNCC2 |
[2H]c1c(Oc2c(F)ccc(NS(=O)(=O)N(C)CC)c2C#N)c([2H])c2c(=O)n([C@H]3COC4(CCN(C(=O)CC5(O)CCN(c6cc7c(cc6F)c(N6CCC(=O)NC6=O)nn7C)CC5)CC4)C3)cnc2c1[2H] |
CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1cc3c(c4c1c2C(NC(C)=O)CC4)OC(F)(F)O3 |
CN(C(=O)CCN1CCC(=O)CC1)c1cccc(CS(=O)(=O)N2CCC(Nc3cccc(-c4sc(C(=O)O)c(OCC(=O)O)c4Cl)c3)CC2(C)C)c1 |
Cc1cc(C)c2nc1O[C@H](C)CCCCC[C@@](C)(O)c1nnc-2o1 |
COc1ccccc1-c1cnccc1C(=O)Nc1nnc(OCC2CCCc3[nH]ncc32)s1 |
C[C@@H]1CN(CC(=O)N2CC(C)(C)c3nc(O[Si](C)(C)C(C)(C)C)c(Cc4ccc(F)cc4)cc32)[C@@H](CO)CN1C(=O)OC(C)(C)C |
Cc1cc(-c2cc3c(cc2Nc2cccc4c2C(=O)N(C2CCC(=O)NC2=O)C4=O)N(C)S(=O)(=O)CC3)ccn1 |
C=CC(=O)Nc1ccccc1-n1c(CC)nc2c(c(C)c(C)n2CC(=O)Nc2ccc(C(F)(F)F)cc2)c1=O |
Cn1c(-c2cc3ccc(-c4cccc(O)c4F)nc3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H]1COCCN1)C3=O |
Cc1oc2cnc(OCc3cccnc3C(F)(F)F)cc2c1C(=O)N[C@@H]1CCNCC1(F)F |
CN(C)C(=O)CCNC(=O)OC[C@H](CCN)N1C(=O)C=CC1=O |
CC1(C)CCC(c2ccc(Cl)cc2)=C(CN2CCN(c3ccc(C(=O)NS(=O)(=O)c4ccc(C[C@H](CCN5CCOCC5)CSc5ccccc5)c(S(=O)(=O)C(F)(F)F)c4)cc3)CC2)C1 |
COc1cc(-n2nc3c(=O)c(N4CCN(C(=O)OC(C)(C)C)[C@H]5CC[C@@H]54)c4n(c3n2)C(C(=O)NC23CC(C5CC5)(C2)C3)CC4C)ccn1 |
NC1(CO)CCNC1=O |
CC(C)(C)OC(=O)N1CC[C@H]2C[C@@H]1c1c(F)cc(C(F)(F)F)cc1O2 |
Cc1cc(Nc2ncnc3cc(NS(=O)(=O)CCO)cc(N4CCC5(CC4)CC5)c23)cc(N2CCC(F)(F)CC2)n1 |
CC[C@@H]1CN(Cc2cc([C@@H](c3ccc4c(nnn4C)c3C)C(C)(C)C(=O)O)cc3c2CCC3)S(=O)(=O)c2cc(Cl)cnc2O1 |
CC(C)(C)OC(=O)N[C@@H]1CCCCc2c1ccc(-c1ncnn3cccc13)c2F |
OB(O)c1c(C2CC2)c(Cl)cc2c1cnn2C1CCCCO1 |
CCN(C)S(=O)(=O)Nc1ccc(F)c(Nc2ccc3ncn([C@H]4COC5(CCN(C(=O)CC6(O)CCN(c7cc8c(cc7F)c(N7CCC(=O)NC7=O)nn8C)CC6)CC5)C4)c(=O)c3c2F)c1C#N |
COc1cc2c(cc1C(=O)N[C@H]1[C@@H](C(=O)Nc3ccc(F)c(C(F)(F)F)c3)[C@H]3CC[C@@H]1/C3=C\C1CC1)CCN(CCCO)C2 |
Cc1nccc2[nH]c(=O)n(CC(=O)N[C@@H](C)c3ncc(C#N)cc3F)c(=O)c12 |
COC(=O)c1c(-c2cnn(CC34CC5CC(CC(C5)C3)C4)c2C)ccc2nc(-c3cccc4ccc(C(=O)Nc5nc6ccccc6s5)cc34)ccc12 |
CCc1c(N2CCN(C(=O)OC(C)(C)C)CC2)c(=O)c2nc(Br)c(CCN(C)C(=O)OCc3ccccc3)nc2n1Cc1ccc(OC)cc1 |
Cc1nnc(-c2c(CC3(c4ccc(F)cc4)CC3)nc(CC(C)C)c(C(N)=O)c2-c2ccc(C(=O)NCc3ccc(F)c(F)c3)s2)o1 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.