{
  "claim_levels": {
    "four_group_interaction": "auxiliary",
    "independent_validation": "not_achieved_without_verifiable_external_cohort",
    "main_C1": "observational",
    "therapeutic": "observational"
  },
  "completion_utc": "2026-11-04T22:16:12.916243+00:00",
  "main_C1_count": 83,
  "main_selected_all_contexts": 546,
  "output_root": "/kaggle/working/final_comutation_fresh_20261104_192636_UTC",
  "raw_source_policy": "ONLY_OFFICIAL_UPSTREAM_DATA; NO_HISTORICAL_RESULTS",
  "research_status": "RAW_DATA_COMPUTATIONAL_RUN_COMPLETE",
  "researcher_review": "PENDING",
  "run_seconds": 10176.768191217001,
  "therapeutic": {
    "causal_mechanism_established": false,
    "interpretation": "Conditional drug response support differs from A-by-B nonadditive interaction or clinical therapeutic effect",
    "n_AB_vs_Bonly_BH": 0,
    "n_AB_vs_Bonly_tested": 50,
    "n_PRISM_BH_concordant": 8,
    "n_PRISM_BY_concordant": 5,
    "n_PRISM_conditional_tested": 49,
    "n_annotated_drug_hypotheses": 62,
    "n_external_independently_validated": 0,
    "n_fresh_C1": 83,
    "n_strict_AxB_BH": 0,
    "n_strict_interactions_tested": 31,
    "raw_data_only_no_prior_results": true,
    "study": "FRESH raw-source drug-response followup"
  }
}