{
  "task_id": "grpr-yap1-nuclear-localization",
  "task_version": "1.0.0",
  "groups": [
    {
      "group_id": "g1",
      "label": "1057: reported nuclear YAP1 percentage at 1 h",
      "item_ids": [
        "exp_e6289a602e28",
        "exp_9d9e09590f28",
        "exp_8dc15e7a1dbc",
        "exp_40b8c244b5a3"
      ],
      "direction": "ascending",
      "group_weight": 1.0,
      "k": 2,
      "epsilon": 0,
      "uncertainty_model": "optional_reported_uncertainty",
      "difference_standard_error": "sem_sum_upper_bound",
      "endpoint": {
        "name": "reported nuclear YAP1 percentage",
        "unit": "%",
        "definition_en": "Arithmetic mean of the reported percentages of cells displaying nuclear YAP1 localization. The endpoint is a positive-cell fraction, as explicitly defined by the figure caption. The exact image segmentation threshold and cell-level nuclear-positive classification algorithm are not supplied."
      }
    }
  ],
  "scoring_method": "spearman",
  "primary_score": "task_spearman",
  "spearman_range": [
    -1,
    1
  ],
  "spearman_tie_method": "average",
  "spearman_undefined_policy": "task_error",
  "spearman_aggregation": "Pearson correlation of true average ranks and submitted positions, separately within each group, then fixed group-weighted sum; do not pool groups or clip negative groups.",
  "secondary_scoring_method": "equal_pair_inversion_random95",
  "ranking_reward_range": [
    0,
    1
  ],
  "random_quantile": 0.95,
  "unknown_uncertainty_policy": "use_reported_value",
  "pair_rule": "For each unordered pair, count it iff abs(mu_i-mu_j)>k*s_ij+epsilon for known uncertainty, or >epsilon for unknown uncertainty. Each counted pair has equal weight within its group. Unknown uncertainty is not zero uncertainty.",
  "ranking_reward_formula": "Validate finite 0.5<=q<1 and 0<=A<=1; if A==1 return 1; else if A<=q+1e-12 return 0; otherwise clamp((A-q)/(1-q),0,1). A is the fixed weighted sum of group pair accuracies; q is the whole-task random 95th percentile.",
  "format_errors": {
    "whole_task": "Core=-1; auxiliary=0 for malformed/oversized/non-UTF8 JSON, duplicate object keys, wrong/missing identity, invalid top-level/rankings, unknown or unassignable group.",
    "known_group": "Missing/duplicate known group or invalid item permutation: raw group Spearman=null, aggregation value=-1, group pair accuracy=0; preserve group weight and apply auxiliary threshold after aggregation."
  },
  "max_submission_bytes": 1048576,
  "minimum_conditions_per_group": 2,
  "time_limit_sec": 28800,
  "solver_resources": {
    "cpus": 8,
    "memory_mb": 16384,
    "gpus": 1,
    "gpu_types": [
      "H20"
    ]
  },
  "submission_path": "/logs/artifacts/rankings.json",
  "report_path": "/logs/artifacts/report.md",
  "sources_path": "/logs/artifacts/sources.json",
  "analysis_path": "/logs/artifacts/analysis/",
  "forbidden_result_scope": "Measured outcomes of these or equivalent melanoma cell assays under GRP, RC-3095, receptor transfection or matched controls are prohibited. This covers same-type experimental cell-growth, anoikis, invasion, receptor-second-messenger and localization results, numerical/qualitative comparisons from other sources and models fitted to those outcomes; general drug/receptor chemistry and measurement theory remain permitted."
}